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Gene: AOC1 (amine oxidase copper containing 1) Homo sapiens
Symbol: AOC1
Name: amine oxidase copper containing 1
Description: Exhibits several functions, including heparin binding activity; metal ion binding activity; and oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor. Involved in several processes, including cellular response to azide; cellular response to copper ion starvation; and cellular response to histamine. Localizes to extracellular exosome and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABP; ABP1; amiloride binding protein 1; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride-binding protein 1; amiloride-binding protein-1; amiloride-sensitive amine oxidase; amiloride-sensitive amine oxidase [copper-containing]; amine oxidase copper domain-containing protein 1; amine oxidase, copper containing 1; DAO; DAO1; diamine oxidase; histaminase; KAO; kidney amine oxidase
Mus musculus (house mouse) : Aoc1 (amine oxidase, copper-containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aoc1 (amine oxidase, copper containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aoc1 (amine oxidase copper containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AOC1 (amine oxidase copper containing 1)
Canis lupus familiaris (dog) : AOC1 (amine oxidase copper containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aoc1 (amine oxidase copper containing 1)
Sus scrofa (pig) : AOC1 (amine oxidase copper containing 1)
Chlorocebus sabaeus (African green monkey) : AOC1 (amine oxidase copper containing 1)
Heterocephalus glaber (naked mole-rat) : Aoc1 (amine oxidase copper containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl7150,824,627 - 150,861,504 (+)EnsemblGRCh38hg38GRCh38
GRCh387150,824,875 - 150,861,504 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377150,524,336 - 150,558,379 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,180,506 - 150,189,312 (+)NCBINCBI36hg18NCBI36
Build 347149,987,239 - 149,996,025NCBI
Celera7145,106,596 - 145,115,402 (+)NCBI
Cytogenetic Map7q36.1ENTREZGENE
HuRef7144,361,610 - 144,370,427 (+)NCBIHuRef
CHM1_17150,557,803 - 150,566,593 (+)NCBICHM1_1
CRA_TCAGchr7v27149,878,851 - 149,887,665 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AOC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732341
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.