AOC1 (amine oxidase copper containing 1) - Rat Genome Database

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Gene: AOC1 (amine oxidase copper containing 1) Sus scrofa
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Symbol: AOC1
Name: amine oxidase copper containing 1
RGD ID: 13918368
Description: ENCODES a protein that exhibits diamine oxidase activity; copper ion binding (ortholog); heparin binding (ortholog); INVOLVED IN putrescine metabolic process; response to antibiotic; amiloride transport (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Experimental Diabetes Mellitus (ortholog); hypertension (ortholog); FOUND IN plasma membrane; bicellular tight junction (ortholog); extracellular space (ortholog); INTERACTS WITH cobalt dichloride; copper(II) chloride; Phenylamil
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ABP1; amiloride binding protein 1 (amine oxidase (copper-containing)); Amiloride-binding protein 1; Amiloride-sensitive amine oxidase; amiloride-sensitive amine oxidase [copper-containing]; Amine oxidase copper domain-containing protein 1; DAO; Diamine oxidase; Histaminase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,309,594 - 6,320,974 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,309,583 - 6,321,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,738,053 - 6,749,392 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:7626074   PMID:8144586   PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
AOC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,309,594 - 6,320,974 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1186,309,583 - 6,321,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,738,053 - 6,749,392 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AOC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387150,852,120 - 150,861,504 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl7150,824,627 - 150,861,504 (+)EnsemblGRCh38hg38GRCh38
GRCh377150,549,605 - 150,558,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,180,506 - 150,189,312 (+)NCBINCBI36hg18NCBI36
Build 347149,987,239 - 149,996,025NCBI
Celera7145,106,596 - 145,115,402 (+)NCBI
Cytogenetic Map7q36.1ENTREZGENE
HuRef7144,361,610 - 144,370,427 (+)NCBIHuRef
CHM1_17150,557,803 - 150,566,593 (+)NCBICHM1_1
T2T-CHM13v2.07152,025,287 - 152,034,270 (+)NCBI
CRA_TCAGchr7v27149,878,851 - 149,887,665 (+)NCBI
Aoc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39648,872,189 - 48,886,122 (+)NCBIGRCm39mm39
GRCm39 Ensembl648,849,830 - 48,886,122 (+)Ensembl
GRCm38648,895,255 - 48,909,188 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl648,872,896 - 48,909,188 (+)EnsemblGRCm38mm10GRCm38
MGSCv37648,845,254 - 48,859,186 (+)NCBIGRCm37mm9NCBIm37
MGSCv36648,824,840 - 48,838,774 (+)NCBImm8
Celera649,405,009 - 49,418,946 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map623.78NCBI
Aoc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2477,812,260 - 77,831,846 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl477,812,260 - 77,831,840 (+)Ensembl
Rnor_6.0478,496,043 - 78,515,582 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl478,496,043 - 78,515,584 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04143,183,686 - 143,203,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4476,957,477 - 76,977,643 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1477,247,444 - 77,253,779 (+)NCBI
Celera472,749,277 - 72,768,814 (+)NCBICelera
Cytogenetic Map4q24NCBI
Aoc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,316,476 - 5,326,305 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,316,482 - 5,326,262 (+)NCBIChiLan1.0ChiLan1.0
AOC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17154,586,931 - 154,595,248 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7154,563,523 - 154,595,248 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07142,434,732 - 142,443,050 (+)NCBIMhudiblu_PPA_v0panPan3
AOC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11614,955,528 - 14,963,283 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1614,958,658 - 15,036,651 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1615,563,706 - 15,571,546 (+)NCBI
ROS_Cfam_1.01616,671,139 - 16,678,130 (+)NCBI
UMICH_Zoey_3.11615,049,911 - 15,057,763 (+)NCBI
UNSW_CanFamBas_1.01615,631,448 - 15,639,287 (+)NCBI
UU_Cfam_GSD_1.01615,681,981 - 15,689,844 (+)NCBI
Aoc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051186,590,547 - 6,597,512 (-)NCBI
SpeTri2.0NW_0049365276,309,210 - 6,312,869 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AOC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,037,498 - 119,046,875 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,038,356 - 119,047,279 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607215,014,229 - 15,018,767 (+)NCBIVero_WHO_p1.0
Aoc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248005,739,034 - 5,749,608 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248005,739,076 - 5,749,567 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system hemolymphoid system renal system reproductive system respiratory system
High
Medium 8 2 2
Low 1 2 1 1
Below cutoff 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000037065   ⟹   ENSSSCP00000038000
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl186,309,594 - 6,320,974 (-)Ensembl
RefSeq Acc Id: XM_003134553   ⟹   XP_003134601
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,309,583 - 6,321,016 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078683   ⟹   XP_020934342
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,309,583 - 6,318,082 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078684   ⟹   XP_020934343
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,309,583 - 6,317,798 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078685   ⟹   XP_020934344
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,309,583 - 6,320,969 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078686   ⟹   XP_020934345
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1186,309,583 - 6,314,055 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_003134601   ⟸   XM_003134553
- UniProtKB: Q9TRC7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_020934344   ⟸   XM_021078685
- Sequence:
RefSeq Acc Id: XP_020934342   ⟸   XM_021078683
- Sequence:
RefSeq Acc Id: XP_020934343   ⟸   XM_021078684
- Sequence:
RefSeq Acc Id: XP_020934345   ⟸   XM_021078686
- Sequence:
RefSeq Acc Id: ENSSSCP00000038000   ⟸   ENSSSCT00000037065

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016442 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005005767 UniProtKB/TrEMBL
  ENSSSCG00025032943 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00030022841 UniProtKB/TrEMBL
  ENSSSCG00035015210 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSSSCG00040075350 UniProtKB/TrEMBL
  ENSSSCG00045013340 UniProtKB/TrEMBL
  ENSSSCG00055019473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000038000 ENTREZGENE
  ENSSSCP00000038000.2 UniProtKB/TrEMBL
  ENSSSCP00005005105.1 UniProtKB/TrEMBL
  ENSSSCP00005005141.1 UniProtKB/TrEMBL
  ENSSSCP00005005150.1 UniProtKB/TrEMBL
  ENSSSCP00005005187.1 UniProtKB/TrEMBL
  ENSSSCP00025019136 UniProtKB/Swiss-Prot
  ENSSSCP00025019184.1 UniProtKB/TrEMBL
  ENSSSCP00025019219.1 UniProtKB/TrEMBL
  ENSSSCP00030014254.1 UniProtKB/TrEMBL
  ENSSSCP00030014266.1 UniProtKB/TrEMBL
  ENSSSCP00035006878 UniProtKB/Swiss-Prot
  ENSSSCP00035006884.1 UniProtKB/TrEMBL
  ENSSSCP00035006888.1 UniProtKB/TrEMBL
  ENSSSCP00040047613.1 UniProtKB/TrEMBL
  ENSSSCP00040047631.1 UniProtKB/TrEMBL
  ENSSSCP00040047660.1 UniProtKB/TrEMBL
  ENSSSCP00045015695.1 UniProtKB/TrEMBL
  ENSSSCP00045015718.1 UniProtKB/TrEMBL
  ENSSSCP00045015746.1 UniProtKB/TrEMBL
  ENSSSCP00055030307.1 UniProtKB/TrEMBL
  ENSSSCP00055030417 UniProtKB/Swiss-Prot
  ENSSSCP00055030511.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000037065 ENTREZGENE
  ENSSSCT00000037065.2 UniProtKB/TrEMBL
  ENSSSCT00005008678.1 UniProtKB/TrEMBL
  ENSSSCT00005008715.1 UniProtKB/TrEMBL
  ENSSSCT00005008727.1 UniProtKB/TrEMBL
  ENSSSCT00005008779.1 UniProtKB/TrEMBL
  ENSSSCT00025044925 UniProtKB/Swiss-Prot
  ENSSSCT00025045024.1 UniProtKB/TrEMBL
  ENSSSCT00025045113.1 UniProtKB/TrEMBL
  ENSSSCT00030031720.1 UniProtKB/TrEMBL
  ENSSSCT00030031742.1 UniProtKB/TrEMBL
  ENSSSCT00035019360 UniProtKB/Swiss-Prot
  ENSSSCT00035019371.1 UniProtKB/TrEMBL
  ENSSSCT00035019376.1 UniProtKB/TrEMBL
  ENSSSCT00040104492.1 UniProtKB/TrEMBL
  ENSSSCT00040104515.1 UniProtKB/TrEMBL
  ENSSSCT00040104551.1 UniProtKB/TrEMBL
  ENSSSCT00045022749.1 UniProtKB/TrEMBL
  ENSSSCT00045022784.1 UniProtKB/TrEMBL
  ENSSSCT00045022822.1 UniProtKB/TrEMBL
  ENSSSCT00055038149.1 UniProtKB/TrEMBL
  ENSSSCT00055038288 UniProtKB/Swiss-Prot
  ENSSSCT00055038406.1 UniProtKB/TrEMBL
Gene3D-CATH 2.70.98.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cu_amine_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cu_amine_oxidase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cu_amine_oxidase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cu_amine_oxidase_N-reg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cu_amine_oxidase_N2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cu_amine_oxidase_N3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100517436 UniProtKB/Swiss-Prot
NCBI Gene AOC1 ENTREZGENE
PANTHER PTHR10638 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cu_amine_oxid UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cu_amine_oxidN2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cu_amine_oxidN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS CUDAOXIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE COPPER_AMINE_OXID_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  COPPER_AMINE_OXID_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49998 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54416 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5S6HCB7_PIG UniProtKB/TrEMBL
  A0A8D0I6N9_PIG UniProtKB/TrEMBL
  A0A8D0I6S2_PIG UniProtKB/TrEMBL
  A0A8D0RNC9_PIG UniProtKB/TrEMBL
  A0A8D0UPF3_PIG UniProtKB/TrEMBL
  A0A8D0W0E3_PIG UniProtKB/TrEMBL
  A0A8D0W0F4_PIG UniProtKB/TrEMBL
  A0A8D1H9W3_PIG UniProtKB/TrEMBL
  A0A8D1HA03_PIG UniProtKB/TrEMBL
  A0A8D1KMF3_PIG UniProtKB/TrEMBL
  A0A8D1KVB3_PIG UniProtKB/TrEMBL
  AOC1_PIG UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary F1SSL3 UniProtKB/Swiss-Prot
  Q29317 UniProtKB/Swiss-Prot
VGNC ID VGNC:85375 ENTREZGENE