Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: AQP1 (aquaporin 1 (Colton blood group)) Homo sapiens
Symbol: AQP1
Name: aquaporin 1 (Colton blood group)
Description: Exhibits identical protein binding activity and transmembrane transporter activity. Involved in several processes, including body fluid secretion; cellular response to reactive oxygen species; and water homeostasis. Localizes to several cellular components, including the basal plasma membrane; brush border membrane; and extracellular exosome. Colocalizes with the symbiont-containing vacuole membrane. Biomarker of central pontine myelinolysis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AQP-1; AQP-CHIP; aquaporin 1; aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; aquaporin 1aquaporin 1 (Colton blood group); aquaporin-1; aquaporin-CHIP; channel-like integral membrane protein, 28-kDa; CHIP28; CO; Colton blood group; MGC26324; urine water channel; water channel protein for red blood cells and kidney proximal tubule
Mus musculus (house mouse) : Aqp1 (aquaporin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aqp1 (aquaporin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aqp1 (aquaporin 1 (Colton blood group))
Pan paniscus (bonobo/pygmy chimpanzee) : AQP1 (aquaporin 1 (Colton blood group))
Canis lupus familiaris (dog) : AQP1 (aquaporin 1 (Colton blood group))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aqp1 (aquaporin 1 (Colton blood group))
Sus scrofa (pig) : AQP1 (aquaporin 1 (Colton blood group))
Chlorocebus sabaeus (green monkey) : AQP1 (aquaporin 1 (Colton blood group))
Heterocephalus glaber (naked mole-rat) : Aqp1 (aquaporin 1 (Colton blood group))
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl730,911,694 - 30,925,517 (+)Ensembl
GRCh38730,911,694 - 30,925,517 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37730,951,415 - 30,965,131 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,917,993 - 30,931,656 (+)NCBINCBI36hg18NCBI36
Build 34730,724,707 - 30,738,371NCBI
Celera730,940,621 - 30,954,337 (+)NCBI
Cytogenetic Map7p14.3NCBI
HuRef730,833,637 - 30,847,351 (+)NCBIHuRef
CHM1_1730,951,350 - 30,965,064 (+)NCBICHM1_1
CRA_TCAGchr7v2731,000,921 - 31,014,637 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AQP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70369
Created: 2002-03-20
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.