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Gene: MMP1 (matrix metallopeptidase 1) Homo sapiens
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Symbol: MMP1
Name: matrix metallopeptidase 1
Description: Exhibits metalloendopeptidase activity. Involved in positive regulation of protein complex assembly and proteolysis. Predicted to localize to the extracellular region. Implicated in several diseases, including artery disease (multiple); female reproductive organ cancer (multiple); intrinsic cardiomyopathy (multiple); obstructive lung disease (multiple); and urinary system cancer (multiple). Biomarker of several diseases, including artery disease (multiple); arthritis (multiple); idiopathic pulmonary fibrosis; psoriatic arthritis; and rheumatic disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLG; CLGN; fibroblast collagenase; interstitial collagenase; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1 (interstitial collagenase)
Orthologs:
Mus musculus (house mouse) : Mmp1a (matrix metallopeptidase 1a (interstitial collagenase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Mmp1 (matrix metallopeptidase 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MMP1 (matrix metallopeptidase 1)
Canis lupus familiaris (dog) : MMP1 (matrix metallopeptidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp1 (matrix metallopeptidase 1)
Sus scrofa (pig) : MMP1 (matrix metallopeptidase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811102,789,919 - 102,798,160 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711102,660,641 - 102,668,966 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,165,861 - 102,174,104 (-)NCBINCBI36hg18NCBI36
Build 3411102,165,860 - 102,174,104NCBI
Celera1199,822,300 - 99,830,624 (-)NCBI
Cytogenetic Map11q22.2NCBI
HuRef1198,588,616 - 98,596,940 (-)NCBIHuRef
CHM1_111102,543,487 - 102,551,813 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MMP1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317388
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.