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Gene: MMP1 (matrix metallopeptidase 1) Homo sapiens
Symbol: MMP1
Name: matrix metallopeptidase 1
Description: Exhibits metalloendopeptidase activity. Involved in positive regulation of protein complex assembly and proteolysis. Predicted to localize to the extracellular region. Implicated in several diseases, including artery disease (multiple); female reproductive organ cancer (multiple); intrinsic cardiomyopathy (multiple); obstructive lung disease (multiple); and urinary system cancer (multiple). Biomarker of several diseases, including artery disease (multiple); arthritis (multiple); idiopathic pulmonary fibrosis; psoriatic arthritis; and rheumatic disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLG; CLGN; fibroblast collagenase; interstitial collagenase; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1 (interstitial collagenase)
Mus musculus (house mouse) : Mmp1a (matrix metallopeptidase 1a (interstitial collagenase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Mmp1 (matrix metallopeptidase 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MMP1 (matrix metallopeptidase 1)
Canis lupus familiaris (dog) : MMP1 (matrix metallopeptidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp1 (matrix metallopeptidase 1)
Sus scrofa (pig) : MMP1 (matrix metallopeptidase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3811102,789,919 - 102,798,160 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711102,660,641 - 102,668,966 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,165,861 - 102,174,104 (-)NCBINCBI36hg18NCBI36
Build 3411102,165,860 - 102,174,104NCBI
Celera1199,822,300 - 99,830,624 (-)NCBI
Cytogenetic Map11q22.2NCBI
HuRef1198,588,616 - 98,596,940 (-)NCBIHuRef
CHM1_111102,543,487 - 102,551,813 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MMP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317388
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.