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Gene: ABAT (4-aminobutyrate aminotransferase) Homo sapiens
Symbol: ABAT
Name: 4-aminobutyrate aminotransferase
Description: Exhibits protein homodimerization activity and pyridoxal phosphate binding activity. Contributes to 4-aminobutyrate transaminase activity. Predicted to be involved in behavioral response to cocaine and gamma-aminobutyric acid catabolic process. Localizes to the 4-aminobutyrate transaminase complex and mitochondrion. Implicated in Alzheimer's disease; GABA aminotransferase deficiency; and Huntington's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase, mitochondrial; 4-aminobutyrate transaminase; FLJ17813; FLJ30272; GABA aminotransferase; GABA transaminase; GABA transferase; GABA-AT; GABAT; gamma-amino-N-butyrate transaminase; gamma-aminobutyrate aminotransferase; hCG1984265; NPD009
Mus musculus (house mouse) : Abat (4-aminobutyrate aminotransferase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abat (4-aminobutyrate aminotransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abat (4-aminobutyrate aminotransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ABAT (4-aminobutyrate aminotransferase)
Canis lupus familiaris (dog) : ABAT (4-aminobutyrate aminotransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abat (4-aminobutyrate aminotransferase)
Sus scrofa (pig) : ABAT (4-aminobutyrate aminotransferase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38168,674,617 - 8,784,575 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37168,768,444 - 8,878,432 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36168,675,928 - 8,785,933 (+)NCBINCBI36hg18NCBI36
Build 34168,675,945 - 8,785,932NCBI
Celera168,937,805 - 9,047,806 (+)NCBI
Cytogenetic Map16p13.2NCBI
HuRef168,691,116 - 8,800,895 (+)NCBIHuRef
CHM1_1168,768,357 - 8,878,342 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ABAT
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732065
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.