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Gene: ADD2 (adducin 2) Homo sapiens
Symbol: ADD2
Name: adducin 2
Description: Exhibits cytoskeletal protein binding activity; protein dimerization activity; and protein kinase binding activity. Involved in several processes, including actin filament bundle assembly; barbed-end actin filament capping; and leukocyte tethering or rolling. Localizes to the F-actin capping protein complex; cytoplasmic vesicle; and plasma membrane raft. Implicated in IgA glomerulonephritis and hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADDB; adducin 2 (beta); adducin 2, beta; beta adducin; beta-adducin; erythrocyte adducin subunit beta
Mus musculus (house mouse) : Add2 (adducin 2 (beta))  MGI  Alliance
Rattus norvegicus (Norway rat) : Add2 (adducin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Add2 (adducin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ADD2 (adducin 2)
Canis lupus familiaris (dog) : ADD2 (adducin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Add2 (adducin 2)
Sus scrofa (pig) : ADD2 (adducin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38270,656,784 - 70,768,200 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37270,888,334 - 70,995,375 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36270,742,770 - 70,848,837 (-)NCBINCBI36hg18NCBI36
Build 34270,800,919 - 70,906,984NCBI
Celera270,739,895 - 70,846,052 (-)NCBI
Cytogenetic Map2p13.3NCBI
HuRef270,626,283 - 70,732,257 (-)NCBIHuRef
CHM1_1270,818,535 - 70,924,705 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ADD2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736575
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.