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Gene: STRA6 (stimulated by retinoic acid 6) Homo sapiens
Symbol: STRA6
Name: stimulated by retinoic acid 6
Description: The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ12541; MCOPCB8; MCOPS9; PP14296; receptor for retinol uptake STRA6; retinol binding protein 4 receptor; retinol-binding protein receptor STRA6; stimulated by retinoic acid 6 homolog; stimulated by retinoic acid gene 6 homolog; stimulated by retinoic acid gene 6 protein homolog
Mus musculus (house mouse) : Stra6 (stimulated by retinoic acid gene 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Stra6 (stimulated by retinoic acid 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stra6 (stimulated by retinoic acid 6)
Pan paniscus (bonobo/pygmy chimpanzee) : STRA6 (stimulated by retinoic acid 6)
Canis lupus familiaris (dog) : STRA6 (stimulated by retinoic acid 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stra6 (stimulated by retinoic acid 6)
Sus scrofa (pig) : STRA6 (stimulated by retinoic acid 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381574,179,466 - 74,212,267 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371574,471,802 - 74,502,046 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,258,860 - 72,282,245 (-)NCBINCBI36hg18NCBI36
Build 341572,258,862 - 72,282,245NCBI
Celera1551,418,988 - 51,448,552 (-)NCBI
Cytogenetic Map15q24.1NCBI
HuRef1551,265,478 - 51,295,736 (-)NCBIHuRef
CHM1_11574,590,002 - 74,620,238 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on STRA6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347443
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.