NOX4 (NADPH oxidase 4) - Rat Genome Database

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Pathways
Gene: NOX4 (NADPH oxidase 4) Homo sapiens
Analyze
Symbol: NOX4
Name: NADPH oxidase 4
RGD ID: 731542
HGNC Page HGNC:7891
Description: Enables heme binding activity; modified amino acid binding activity; and oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor. Involved in several processes, including heart process; homocysteine metabolic process; and superoxide metabolic process. Located in several cellular components, including endoplasmic reticulum membrane; nucleolus; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: kidney oxidase-1; kidney superoxide-producing NADPH oxidase; KOX; KOX-1; renal NAD(P)H-oxidase; RENOX
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: NOX4P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381189,324,353 - 89,589,557 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1189,324,353 - 89,498,187 (-)Ensemblhg38GRCh38
GRCh371189,057,521 - 89,322,725 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361188,699,160 - 88,864,301 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341188,699,159 - 88,864,301NCBI
Celera1185,399,612 - 85,574,418 (+)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,294,642 - 85,559,923 (-)NCBIHuRef
CHM1_11188,940,465 - 89,205,767 (-)NCBICHM1_1
T2T-CHM13v2.01189,244,014 - 89,509,286 (-)NCBIT2T-CHM13v2.0
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(R)-lipoic acid  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (EXP)
1,4-bis(2-ethylhexyl) sulfosuccinate  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
acetamide  (ISO)
aflatoxin B1  (EXP)
Aflatoxin B2 alpha  (EXP)
agomelatine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP)
alpha-D-galactose  (ISO)
amitrole  (ISO)
amlodipine  (ISO)
ammonium chloride  (ISO)
amsacrine  (EXP)
angiotensin II  (EXP,ISO)
antirheumatic drug  (EXP)
apocynin  (EXP,ISO)
aristolochic acid A  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP)
atorvastatin calcium  (EXP,ISO)
aucubin  (EXP,ISO)
bellidifolin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (EXP)
beta-naphthoflavone  (ISO)
bezafibrate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
bosentan  (EXP)
bromobenzene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (EXP,ISO)
calcium oxalate  (ISO)
candesartan  (EXP,ISO)
cannabidiol  (EXP,ISO)
capsaicin  (EXP)
carbamazepine  (EXP)
carbon nanotube  (ISO)
carteolol  (EXP)
carvacrol  (ISO)
CGP-42112A  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium atom  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
colistin  (EXP,ISO)
corosolic acid  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
cytarabine  (EXP)
D-glucose  (EXP,ISO)
dapsone  (EXP,ISO)
daunorubicin  (EXP,ISO)
decabromodiphenyl ether  (EXP,ISO)
Deoxycorticosterone acetate  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Diallyl sulfide  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP)
dibenz[a,h]anthracene  (ISO)
dibenziodolium  (EXP)
dichloroacetic acid  (ISO)
diethyl phthalate  (ISO)
dihydrogen  (ISO)
dioxygen  (EXP,ISO)
diprotium  (ISO)
doxorubicin  (ISO)
doxycycline  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
erlotinib hydrochloride  (EXP)
ethanol  (ISO)
ethoxyquin  (ISO)
farrerol  (ISO)
fenthion  (ISO)
ferric oxide  (ISO)
fisetin  (ISO)
flavonoids  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (EXP)
fructose  (ISO)
furan  (ISO)
galactose  (ISO)
ginkgolide B  (ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
glyoxylic acid  (ISO)
GW 6471  (ISO)
hesperetin  (EXP,ISO)
homocysteine  (EXP)
hydrazine  (ISO)
hydrochlorothiazide  (ISO)
hydrogen peroxide  (EXP)
hydrogen sulfide  (ISO)
hydroquinone  (EXP)
hydroxylamine  (ISO)
Ile(5)-angiotensin II  (EXP,ISO)
indoxyl sulfate  (EXP)
inulin  (ISO)
isoprenaline  (ISO)
kaempferol  (EXP)
L-ascorbic acid  (EXP,ISO)
L-methionine  (ISO)
lanthanum trichloride  (ISO)
lead diacetate  (ISO)
lead(0)  (EXP,ISO)
lead(II) chloride  (EXP)
Leonurine  (ISO)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
liraglutide  (ISO)
loganin  (ISO)
lutein  (ISO)
LY294002  (EXP)
mancozeb  (ISO)
manidipine  (ISO)
melatonin  (EXP,ISO)
menadione  (ISO)
mercury atom  (EXP)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP)
methyl vanillate  (EXP)
methylphenidate  (ISO)
microcystin-LR  (ISO)
mitogen  (ISO)
monocrotaline  (ISO)
Morroniside  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naringin  (EXP)
nicotinamide  (ISO)
nicotine  (ISO)
nicotinic acid  (ISO)
nitroglycerin  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
PD123319  (ISO)
perfluorohexanesulfonic acid  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenethyl caffeate  (EXP)
phenobarbital  (ISO)
PhIP  (ISO)
phosphatidylcholine  (EXP)
pioglitazone  (ISO)
pirfenidone  (ISO)
pirinixic acid  (ISO)
potassium chromate  (EXP)
potassium iodide  (ISO)
probenecid  (EXP)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
roflumilast  (EXP)
rotenone  (ISO)
salubrinal  (ISO)
saxagliptin  (ISO)
SB 203580  (ISO)
selenium atom  (ISO)
sevoflurane  (ISO)
silibinin  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirtinol  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
streptozocin  (ISO)
sulforaphane  (ISO)
sunitinib  (EXP)
superoxide  (EXP)
telmisartan  (ISO)
teprenone  (EXP,ISO)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thioacetamide  (ISO)
thymoquinone  (ISO)
titanium dioxide  (EXP,ISO)
torcetrapib  (EXP)
trans-piceid  (ISO)
trichloroethene  (ISO)
triclosan  (EXP)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tyrphostin AG 1478  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
venetoclax  (EXP)
vinclozolin  (ISO)
zinc atom  (EXP)
zinc dichloride  (EXP)
zinc(0)  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. Cowley AW Jr, etal., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats. Gojo A, etal., Eur J Pharmacol. 2007 Jul 30;568(1-3):242-7. Epub 2007 Apr 20.
4. Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. Gorin Y, etal., J Biol Chem. 2005 Nov 25;280(47):39616-26. Epub 2005 Aug 31.
5. Spinal Cord Injury Leads to Hyperoxidation and Nitrosylation of Skeletal Muscle Ryanodine Receptor-1 Associated with Upregulation of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4. Liu XH, etal., J Neurotrauma. 2017 Jun 15;34(12):2069-2074. doi: 10.1089/neu.2016.4763. Epub 2017 Feb 27.
6. Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis. Matsunami T, etal., Int J Clin Exp Pathol. 2010 May 22;3(5):472-81.
7. Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats. McCann SK, etal., J Neurosci Res. 2008 Aug 15;86(11):2524-34.
8. Differential impacts of mineralocorticoid receptor antagonist potassium canrenoate on liver and renal changes in high fat diet-mediated early hepatocarcinogenesis model rats. Nakamura M, etal., J Toxicol Sci. 2018;43(10):611-621. doi: 10.2131/jts.43.611.
9. The role of NADPH oxidase in chronic intermittent hypoxia-induced pulmonary hypertension in mice. Nisbet RE, etal., Am J Respir Cell Mol Biol. 2009 May;40(5):601-9. Epub 2008 Oct 23.
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Reduced levels of cyclic AMP contribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats. Saha S, etal., Can J Physiol Pharmacol. 2008 Apr;86(4):190-8.
14. Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats. Tada Y, etal., Hypertension. 2009 Sep;54(3):552-7. Epub 2009 Jul 20.
15. Neuronal expression of the NADPH oxidase NOX4, and its regulation in mouse experimental brain ischemia. Vallet P, etal., Neuroscience. 2005;132(2):233-8.
16. Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin. Wang C, etal., Eur J Pharmacol. 2009 Oct 12;620(1-3):131-7. Epub 2009 Aug 15.
17. Upregulation of Nox4 promotes angiotensin II-induced epidermal growth factor receptor activation and subsequent cardiac hypertrophy by increasing ADAM17 expression. Zeng SY, etal., Can J Cardiol. 2013 Oct;29(10):1310-9. doi: 10.1016/j.cjca.2013.04.026. Epub 2013 Jul 11.
Additional References at PubMed
PMID:8889548   PMID:9882350   PMID:10869423   PMID:11032835   PMID:11376945   PMID:11997235   PMID:12477932   PMID:12482831   PMID:14670934   PMID:14702039   PMID:14966267   PMID:15102091  
PMID:15155719   PMID:15210697   PMID:15256399   PMID:15322091   PMID:15342556   PMID:15356101   PMID:15489334   PMID:15509740   PMID:15572675   PMID:15618545   PMID:15706079   PMID:15721269  
PMID:15883163   PMID:15927447   PMID:16019190   PMID:16179589   PMID:16230378   PMID:16249442   PMID:16324151   PMID:16344560   PMID:16532036   PMID:16563235   PMID:16754784   PMID:16987004  
PMID:17064675   PMID:17200123   PMID:17237347   PMID:17369289   PMID:17472580   PMID:17481637   PMID:17501721   PMID:17553579   PMID:17585072   PMID:17717289   PMID:17940286   PMID:17983808  
PMID:18473264   PMID:18508317   PMID:18539955   PMID:18573911   PMID:18593227   PMID:18760347   PMID:18783311   PMID:18845355   PMID:18849343   PMID:19036873   PMID:19057021   PMID:19061439  
PMID:19276355   PMID:19280689   PMID:19299420   PMID:19337723   PMID:19375500   PMID:19388821   PMID:19409979   PMID:19415232   PMID:19540572   PMID:19542021   PMID:19574552   PMID:19657056  
PMID:19671250   PMID:19681754   PMID:19701206   PMID:19779036   PMID:19834108   PMID:19843513   PMID:19913121   PMID:19941336   PMID:19995913   PMID:20031578   PMID:20039838   PMID:20056178  
PMID:20163138   PMID:20177149   PMID:20346360   PMID:20360249   PMID:20375612   PMID:20379614   PMID:20396861   PMID:20403426   PMID:20407038   PMID:20427574   PMID:20457132   PMID:20457808  
PMID:20523116   PMID:20531308   PMID:20628086   PMID:20708598   PMID:20715105   PMID:20925598   PMID:21075166   PMID:21131394   PMID:21273445   PMID:21343298   PMID:21391892   PMID:21399967  
PMID:21443946   PMID:21483469   PMID:21513813   PMID:21732365   PMID:21788590   PMID:21841825   PMID:21873635   PMID:21901141   PMID:21907277   PMID:21915726   PMID:21935366   PMID:21965295  
PMID:22038300   PMID:22095986   PMID:22108207   PMID:22181007   PMID:22277655   PMID:22303451   PMID:22326263   PMID:22456182   PMID:22496405   PMID:22572850   PMID:22659429   PMID:22713363  
PMID:22728268   PMID:22791246   PMID:22937798   PMID:22946340   PMID:23144758   PMID:23251661   PMID:23385065   PMID:23393389   PMID:23476056   PMID:23514110   PMID:23550626   PMID:23555559  
PMID:23612968   PMID:23767990   PMID:23824729   PMID:23824914   PMID:23825596   PMID:23840483   PMID:23917044   PMID:23958997   PMID:23977848   PMID:24027357   PMID:24048704   PMID:24113184  
PMID:24123012   PMID:24205282   PMID:24216508   PMID:24224404   PMID:24239742   PMID:24287775   PMID:24392026   PMID:24450852   PMID:24457954   PMID:24491913   PMID:24494202   PMID:24509161  
PMID:24511132   PMID:24520084   PMID:24560583   PMID:24608713   PMID:24632182   PMID:24714748   PMID:24718857   PMID:24719867   PMID:24755467   PMID:24816588   PMID:24831009   PMID:24947524  
PMID:24965120   PMID:25033544   PMID:25040787   PMID:25062272   PMID:25079350   PMID:25096929   PMID:25146963   PMID:25154738   PMID:25278128   PMID:25315297   PMID:25401479   PMID:25402870  
PMID:25428269   PMID:25504436   PMID:25515000   PMID:25526894   PMID:25557278   PMID:25589557   PMID:25612841   PMID:25645462   PMID:25646414   PMID:25697362   PMID:25706776   PMID:25707572  
PMID:25722086   PMID:25749103   PMID:25841779   PMID:25866826   PMID:25888935   PMID:25891879   PMID:25961022   PMID:25982278   PMID:25998423   PMID:26054376   PMID:26096997   PMID:26222337  
PMID:26238284   PMID:26308771   PMID:26408539   PMID:26473288   PMID:26521743   PMID:26572549   PMID:26582463   PMID:26620565   PMID:26715682   PMID:26742780   PMID:26812119   PMID:26861875  
PMID:26986073   PMID:27052425   PMID:27110716   PMID:27151672   PMID:27155970   PMID:27185859   PMID:27200149   PMID:27221536   PMID:27336467   PMID:27401113   PMID:27435477   PMID:27466293  
PMID:27509686   PMID:27515505   PMID:27525436   PMID:27576129   PMID:27576730   PMID:27614387   PMID:27655718   PMID:27856453   PMID:27870947   PMID:27932314   PMID:27941881   PMID:27986445  
PMID:27989748   PMID:28063381   PMID:28081539   PMID:28088644   PMID:28099519   PMID:28182006   PMID:28232723   PMID:28260074   PMID:28330417   PMID:28336812   PMID:28351775   PMID:28383062  
PMID:28389561   PMID:28422720   PMID:28424170   PMID:28431936   PMID:28487945   PMID:28514442   PMID:28557373   PMID:28592118   PMID:28605812   PMID:28688762   PMID:28751569   PMID:28840773  
PMID:28916474   PMID:29039574   PMID:29047077   PMID:29049376   PMID:29051480   PMID:29087944   PMID:29128359   PMID:29138836   PMID:29269309   PMID:29365138   PMID:29426376   PMID:29459227  
PMID:29491408   PMID:29496628   PMID:29571125   PMID:29674345   PMID:29684820   PMID:29986678   PMID:30012342   PMID:30087027   PMID:30125808   PMID:30178632   PMID:30245133   PMID:30281903  
PMID:30354218   PMID:30362963   PMID:30450923   PMID:30464227   PMID:30630561   PMID:30637800   PMID:30680933   PMID:30681251   PMID:30703252   PMID:30736297   PMID:30769285   PMID:30813866  
PMID:30837663   PMID:31081803   PMID:31119153   PMID:31167233   PMID:31178956   PMID:31179339   PMID:31247506   PMID:31318905   PMID:31434799   PMID:31443922   PMID:31539804   PMID:31585207  
PMID:31626946   PMID:31882567   PMID:31889545   PMID:32240965   PMID:32330605   PMID:32414400   PMID:32492552   PMID:32555397   PMID:32616654   PMID:32641980   PMID:32777344   PMID:32999298  
PMID:33046439   PMID:33153467   PMID:33325804   PMID:33515385   PMID:33548975   PMID:33675939   PMID:33769605   PMID:33774476   PMID:33821883   PMID:33881484   PMID:33961781   PMID:34023385  
PMID:34209278   PMID:34257808   PMID:34740322   PMID:34939720   PMID:35008579   PMID:35075615   PMID:35090586   PMID:35140544   PMID:35269843   PMID:35293283   PMID:35346198   PMID:35348887  
PMID:35377824   PMID:35469044   PMID:35696356   PMID:35719337   PMID:35920301   PMID:36012298   PMID:36043333   PMID:36122532   PMID:36278481   PMID:36372285   PMID:36567907   PMID:36608994  
PMID:36706635   PMID:36804453   PMID:36840500   PMID:36964576   PMID:37019912   PMID:37044213   PMID:37058998   PMID:37081190   PMID:37368156   PMID:37392558   PMID:37463530   PMID:37608820  
PMID:37722070   PMID:37989920   PMID:38092301   PMID:38340945   PMID:38348042   PMID:38379095   PMID:38387281   PMID:38593505   PMID:38663913   PMID:38690939   PMID:38748682   PMID:38943386  


Genomics

Comparative Map Data
NOX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381189,324,353 - 89,589,557 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1189,324,353 - 89,498,187 (-)Ensemblhg38GRCh38
GRCh371189,057,521 - 89,322,725 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361188,699,160 - 88,864,301 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341188,699,159 - 88,864,301NCBI
Celera1185,399,612 - 85,574,418 (+)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,294,642 - 85,559,923 (-)NCBIHuRef
CHM1_11188,940,465 - 89,205,767 (-)NCBICHM1_1
T2T-CHM13v2.01189,244,014 - 89,509,286 (-)NCBIT2T-CHM13v2.0
Nox4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39786,893,638 - 87,047,918 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl786,895,304 - 87,047,918 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38787,244,430 - 87,398,710 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl787,246,096 - 87,398,710 (+)Ensemblmm10GRCm38
MGSCv37794,395,305 - 94,547,116 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36787,122,556 - 87,274,367 (+)NCBIMGSCv36mm8
Celera784,613,741 - 84,757,901 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map748.96NCBI
Nox4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,313,736 - 150,491,480 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1150,313,728 - 150,491,483 (+)EnsemblGRCr8
mRatBN7.21140,900,886 - 141,078,844 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1140,901,097 - 141,077,406 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1148,877,339 - 149,042,590 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01156,047,993 - 156,213,233 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01148,921,890 - 149,087,126 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01150,796,359 - 150,976,186 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1150,797,084 - 150,976,194 (+)Ensemblrn6Rnor6.0
Rnor_5.01157,246,099 - 157,285,107 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01157,106,652 - 157,196,482 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41143,415,816 - 143,603,554 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1139,242,883 - 139,407,667 (+)NCBICelera
RGSC_v3.11143,494,221 - 143,681,960 (+)NCBI
Cytogenetic Map1q32NCBI
Nox4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554144,062,081 - 4,212,746 (+)Ensembl
ChiLan1.0NW_0049554144,062,337 - 4,220,032 (+)NCBIChiLan1.0ChiLan1.0
NOX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2990,148,233 - 90,362,455 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11191,239,494 - 91,406,480 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01184,330,362 - 84,496,755 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11187,911,335 - 88,171,535 (-)NCBIPanPan1.1PanPan1.1panPan2
NOX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12110,615,153 - 10,782,927 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2110,615,970 - 10,775,277 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2110,465,855 - 10,632,710 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02110,796,288 - 10,963,304 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2110,795,550 - 10,960,296 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12110,584,756 - 10,745,644 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02110,643,276 - 10,811,261 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02110,699,999 - 10,861,437 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nox4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494774,947,435 - 75,112,097 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936736230,476 - 396,708 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936736230,465 - 394,859 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl922,624,212 - 22,776,534 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1922,622,105 - 22,776,691 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2925,234,530 - 25,427,884 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NOX4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1180,470,418 - 80,642,513 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl180,470,826 - 80,642,722 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604345,091,781 - 45,259,250 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nox4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624845669,902 - 827,834 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624845669,880 - 829,471 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in NOX4
71 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q14.1-22.3(chr11:78232836-106779420)x1 copy number loss See cases [RCV000052710] Chr11:78232836..106779420 [GRCh38]
Chr11:77943882..106650146 [GRCh37]
Chr11:77621530..106155356 [NCBI36]
Chr11:11q14.1-22.3
pathogenic
GRCh38/hg38 11q14.1-22.2(chr11:85242847-102920097)x1 copy number loss See cases [RCV000052711] Chr11:85242847..102920097 [GRCh38]
Chr11:84953891..102738968 [GRCh37]
Chr11:84631539..102296037 [NCBI36]
Chr11:11q14.1-22.2
pathogenic
NM_001143837.1(NOX4):c.902G>A (p.Arg301Gln) single nucleotide variant Malignant melanoma [RCV000069734] Chr11:89400252 [GRCh38]
Chr11:89133420 [GRCh37]
Chr11:88773068 [NCBI36]
Chr11:11q14.3
not provided
NM_001143836.2(NOX4):c.1136-1662T>A single nucleotide variant Lung cancer [RCV000110399] Chr11:89356705 [GRCh38]
Chr11:89089873 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001143836.2(NOX4):c.629+1160A>G single nucleotide variant Lung cancer [RCV000110400] Chr11:89420742 [GRCh38]
Chr11:89153910 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_001143837.1(NOX4):c.-365+20074G>T single nucleotide variant Lung cancer [RCV000110401] Chr11:89569366 [GRCh38]
Chr11:89302534 [GRCh37]
Chr11:11q14.3
uncertain significance
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3
pathogenic
GRCh38/hg38 11q13.5-22.1(chr11:75941754-98357960)x1 copy number loss See cases [RCV000133838] Chr11:75941754..98357960 [GRCh38]
Chr11:75652798..98228688 [GRCh37]
Chr11:75330446..97733898 [NCBI36]
Chr11:11q13.5-22.1
pathogenic
GRCh38/hg38 11q14.3(chr11:89425778-90689442)x1 copy number loss See cases [RCV000141934] Chr11:89425778..90689442 [GRCh38]
Chr11:89158946..90422610 [GRCh37]
Chr11:88798594..90062258 [NCBI36]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q14.1-21(chr11:80318996-96116221)x1 copy number loss See cases [RCV000446395] Chr11:80318996..96116221 [GRCh37]
Chr11:11q14.1-21
pathogenic
GRCh37/hg19 11q14.2-14.3(chr11:87099219-91921385) copy number loss Abnormal esophagus morphology [RCV000416734] Chr11:87099219..91921385 [GRCh37]
Chr11:11q14.2-14.3
likely benign
GRCh37/hg19 11q14.1-21(chr11:84924674-93574799)x1 copy number loss See cases [RCV000448436] Chr11:84924674..93574799 [GRCh37]
Chr11:11q14.1-21
likely pathogenic
GRCh37/hg19 11q14.2-22.3(chr11:88152458-109414650)x1 copy number loss See cases [RCV000510457] Chr11:88152458..109414650 [GRCh37]
Chr11:11q14.2-22.3
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
NM_016931.5(NOX4):c.17G>A (p.Arg6Lys) single nucleotide variant not specified [RCV004327652] Chr11:89491230 [GRCh38]
Chr11:89224398 [GRCh37]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q13.4-23.3(chr11:71588805-116680918)x3 copy number gain not provided [RCV000683374] Chr11:71588805..116680918 [GRCh37]
Chr11:11q13.4-23.3
pathogenic
GRCh37/hg19 11q14.1-14.3(chr11:81771852-90851187) copy number loss Intellectual disability [RCV000721939] Chr11:81771852..90851187 [GRCh37]
Chr11:11q14.1-14.3
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q14.1-23.2(chr11:80053454-113316236)x1 copy number loss not provided [RCV000737595] Chr11:80053454..113316236 [GRCh37]
Chr11:11q14.1-23.2
pathogenic
GRCh37/hg19 11q14.3(chr11:89276166-89622304)x3 copy number gain not provided [RCV000737619] Chr11:89276166..89622304 [GRCh37]
Chr11:11q14.3
benign
GRCh37/hg19 11q14.3(chr11:89322065-89486848)x3 copy number gain not provided [RCV000737620] Chr11:89322065..89486848 [GRCh37]
Chr11:11q14.3
benign
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11q14.1-21(chr11:83179196-94716998)x3 copy number gain not provided [RCV000750120] Chr11:83179196..94716998 [GRCh37]
Chr11:11q14.1-21
pathogenic
NM_016931.5(NOX4):c.1408C>T (p.Arg470Cys) single nucleotide variant not provided [RCV000968681] Chr11:89340101 [GRCh38]
Chr11:89073269 [GRCh37]
Chr11:11q14.3
benign
NM_016931.5(NOX4):c.285G>A (p.Arg95=) single nucleotide variant not provided [RCV000883988] Chr11:89449504 [GRCh38]
Chr11:89182672 [GRCh37]
Chr11:11q14.3
likely benign
NM_016931.5(NOX4):c.888C>G (p.Ala296=) single nucleotide variant not provided [RCV000968231] Chr11:89400338 [GRCh38]
Chr11:89133506 [GRCh37]
Chr11:11q14.3
benign
NM_016931.5(NOX4):c.672C>T (p.Pro224=) single nucleotide variant not provided [RCV000896476] Chr11:89402500 [GRCh38]
Chr11:89135668 [GRCh37]
Chr11:11q14.3
likely benign
NM_016931.5(NOX4):c.291G>T (p.Leu97Phe) single nucleotide variant not provided [RCV000879136] Chr11:89449498 [GRCh38]
Chr11:89449498..89449499 [GRCh38]
Chr11:89182666 [GRCh37]
Chr11:89182666..89182667 [GRCh37]
Chr11:11q14.3
likely benign
GRCh37/hg19 11q14.3(chr11:88993686-89059590)x3 copy number gain not provided [RCV000847561] Chr11:88993686..89059590 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.28G>A (p.Ala10Thr) single nucleotide variant not specified [RCV004288083] Chr11:89491219 [GRCh38]
Chr11:89224387 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1218-6C>T single nucleotide variant not provided [RCV000974104] Chr11:89342199 [GRCh38]
Chr11:89075367 [GRCh37]
Chr11:11q14.3
benign
GRCh37/hg19 11q14.1-14.3(chr11:84830143-92029933)x3 copy number gain not provided [RCV001006426] Chr11:84830143..92029933 [GRCh37]
Chr11:11q14.1-14.3
pathogenic
GRCh37/hg19 11q14.3(chr11:89062443-89762600)x3 copy number gain not provided [RCV001006431] Chr11:89062443..89762600 [GRCh37]
Chr11:11q14.3
likely benign
GRCh37/hg19 11q14.3(chr11:89071360-89543740)x3 copy number gain not provided [RCV001006432] Chr11:89071360..89543740 [GRCh37]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q14.3(chr11:89278420-89407697)x1 copy number loss not provided [RCV001260142] Chr11:89278420..89407697 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.57+224_57+226dup duplication not provided [RCV001616376] Chr11:89490963..89490964 [GRCh38]
Chr11:89224131..89224132 [GRCh37]
Chr11:11q14.3
benign
NM_016931.5(NOX4):c.910C>T (p.Arg304Trp) single nucleotide variant not specified [RCV004295322] Chr11:89400316 [GRCh38]
Chr11:89133484 [GRCh37]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q14.1-21(chr11:80318996-96116221) copy number loss not specified [RCV002052941] Chr11:80318996..96116221 [GRCh37]
Chr11:11q14.1-21
pathogenic
GRCh37/hg19 11q14.1-23.3(chr11:85422071-118022671)x1 copy number loss not provided [RCV001832892] Chr11:85422071..118022671 [GRCh37]
Chr11:11q14.1-23.3
uncertain significance
GRCh37/hg19 11q14.1-21(chr11:84924674-93574799) copy number loss not specified [RCV002052942] Chr11:84924674..93574799 [GRCh37]
Chr11:11q14.1-21
likely pathogenic
GRCh37/hg19 11q14.1-22.1(chr11:77855209-98002445) copy number loss not specified [RCV002052940] Chr11:77855209..98002445 [GRCh37]
Chr11:11q14.1-22.1
pathogenic
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25
pathogenic
NM_016931.5(NOX4):c.1384G>A (p.Val462Ile) single nucleotide variant not specified [RCV004332105] Chr11:89340125 [GRCh38]
Chr11:89073293 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.352G>A (p.Val118Met) single nucleotide variant not specified [RCV004188925] Chr11:89444230 [GRCh38]
Chr11:89177398 [GRCh37]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q14.1-22.3(chr11:81478509-104667040)x1 copy number loss not provided [RCV002475722] Chr11:81478509..104667040 [GRCh37]
Chr11:11q14.1-22.3
pathogenic
NM_016931.5(NOX4):c.220C>T (p.Pro74Ser) single nucleotide variant not specified [RCV004231101] Chr11:89451829 [GRCh38]
Chr11:89184997 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.503T>C (p.Val168Ala) single nucleotide variant not specified [RCV004199834] Chr11:89432829 [GRCh38]
Chr11:89165997 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.862T>G (p.Ser288Ala) single nucleotide variant not specified [RCV004133117] Chr11:89400364 [GRCh38]
Chr11:89133532 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.232A>G (p.Thr78Ala) single nucleotide variant not specified [RCV004235891] Chr11:89451817 [GRCh38]
Chr11:89184985 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1001G>T (p.Arg334Ile) single nucleotide variant not specified [RCV004121612] Chr11:89400225 [GRCh38]
Chr11:89133393 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.260A>G (p.Gln87Arg) single nucleotide variant not specified [RCV004190214] Chr11:89451789 [GRCh38]
Chr11:89184957 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1472A>G (p.Tyr491Cys) single nucleotide variant not specified [RCV004194682] Chr11:89337490 [GRCh38]
Chr11:89070658 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.889G>A (p.Glu297Lys) single nucleotide variant not specified [RCV004154538] Chr11:89400337 [GRCh38]
Chr11:89133505 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.43A>G (p.Lys15Glu) single nucleotide variant not specified [RCV004180404] Chr11:89491204 [GRCh38]
Chr11:89224372 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1375T>A (p.Phe459Ile) single nucleotide variant not specified [RCV004081068] Chr11:89340134 [GRCh38]
Chr11:89073302 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.642G>T (p.Lys214Asn) single nucleotide variant not specified [RCV004252168] Chr11:89402530 [GRCh38]
Chr11:89135698 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.512T>C (p.Leu171Pro) single nucleotide variant not specified [RCV004266253] Chr11:89432820 [GRCh38]
Chr11:89165988 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.618G>T (p.Leu206Phe) single nucleotide variant not specified [RCV004278676] Chr11:89421913 [GRCh38]
Chr11:89155081 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1036G>A (p.Val346Ile) single nucleotide variant not specified [RCV004328827] Chr11:89400055 [GRCh38]
Chr11:89133223 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.858G>T (p.Trp286Cys) single nucleotide variant not specified [RCV004355319] Chr11:89400368 [GRCh38]
Chr11:89133536 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.943A>G (p.Met315Val) single nucleotide variant not specified [RCV004351149] Chr11:89400283 [GRCh38]
Chr11:89133451 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.502G>T (p.Val168Leu) single nucleotide variant not specified [RCV004354411] Chr11:89432830 [GRCh38]
Chr11:89165998 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1202C>A (p.Ser401Tyr) single nucleotide variant not specified [RCV004488315] Chr11:89354977 [GRCh38]
Chr11:89088145 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1375T>C (p.Phe459Leu) single nucleotide variant not specified [RCV004488316] Chr11:89340134 [GRCh38]
Chr11:89073302 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.311T>G (p.Phe104Cys) single nucleotide variant not specified [RCV004488317] Chr11:89449478 [GRCh38]
Chr11:89182646 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.858G>C (p.Trp286Cys) single nucleotide variant not specified [RCV004488318] Chr11:89400368 [GRCh38]
Chr11:89133536 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.578C>T (p.Thr193Ile) single nucleotide variant not specified [RCV004643993] Chr11:89421953 [GRCh38]
Chr11:89155121 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1081A>G (p.Thr361Ala) single nucleotide variant not specified [RCV004650128] Chr11:89373486 [GRCh38]
Chr11:89106654 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.466T>A (p.Phe156Ile) single nucleotide variant not specified [RCV004650129] Chr11:89440697 [GRCh38]
Chr11:89173865 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.130C>T (p.His44Tyr) single nucleotide variant not specified [RCV004650130] Chr11:89490481 [GRCh38]
Chr11:89223649 [GRCh37]
Chr11:11q14.3
likely benign
NM_016931.5(NOX4):c.1324C>G (p.Leu442Val) single nucleotide variant not specified [RCV004650131] Chr11:89342087 [GRCh38]
Chr11:89075255 [GRCh37]
Chr11:11q14.3
uncertain significance
GRCh37/hg19 11q14.1-22.1(chr11:81041448-98151664)x1 copy number loss not provided [RCV004819372] Chr11:81041448..98151664 [GRCh37]
Chr11:11q14.1-22.1
pathogenic
NM_016931.5(NOX4):c.965T>C (p.Met322Thr) single nucleotide variant not specified [RCV004830177] Chr11:89400261 [GRCh38]
Chr11:89133429 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.170G>A (p.Ser57Asn) single nucleotide variant not specified [RCV004830173] Chr11:89451879 [GRCh38]
Chr11:89185047 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.748C>A (p.Pro250Thr) single nucleotide variant not specified [RCV004830176] Chr11:89402424 [GRCh38]
Chr11:89135592 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1676T>G (p.Leu559Arg) single nucleotide variant not specified [RCV004830180] Chr11:89326817 [GRCh38]
Chr11:89059985 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1001G>A (p.Arg334Lys) single nucleotide variant not specified [RCV004830175] Chr11:89400225 [GRCh38]
Chr11:89133393 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.811A>G (p.Met271Val) single nucleotide variant not specified [RCV004830178] Chr11:89402361 [GRCh38]
Chr11:89135529 [GRCh37]
Chr11:11q14.3
likely benign
NM_016931.5(NOX4):c.508G>A (p.Val170Met) single nucleotide variant not specified [RCV004830179] Chr11:89432824 [GRCh38]
Chr11:89165992 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1567C>T (p.Arg523Cys) single nucleotide variant not specified [RCV004830174] Chr11:89335894 [GRCh38]
Chr11:89069062 [GRCh37]
Chr11:11q14.3
uncertain significance
NC_000011.9:g.89110945_89175769del deletion Oculocutaneous albinism type 1A [RCV005055030] Chr11:89110945..89175769 [GRCh37]
Chr11:11q14.3
likely pathogenic
NM_016931.5(NOX4):c.689A>G (p.Asn230Ser) single nucleotide variant not specified [RCV005377197] Chr11:89402483 [GRCh38]
Chr11:89135651 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.1201T>C (p.Ser401Pro) single nucleotide variant not specified [RCV005377199] Chr11:89354978 [GRCh38]
Chr11:89088146 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.971T>A (p.Ile324Asn) single nucleotide variant not specified [RCV005377195] Chr11:89400255 [GRCh38]
Chr11:89133423 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.158G>A (p.Gly53Glu) single nucleotide variant not specified [RCV005377198] Chr11:89451891 [GRCh38]
Chr11:89185059 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.163T>C (p.Cys55Arg) single nucleotide variant not specified [RCV005383147] Chr11:89451886 [GRCh38]
Chr11:89185054 [GRCh37]
Chr11:11q14.3
uncertain significance
NM_016931.5(NOX4):c.641A>G (p.Lys214Arg) single nucleotide variant not specified [RCV005377196] Chr11:89402531 [GRCh38]
Chr11:89135699 [GRCh37]
Chr11:11q14.3
uncertain significance
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:3422
Count of miRNA genes:871
Interacting mature miRNAs:990
Transcripts:ENST00000263317, ENST00000343727, ENST00000375979, ENST00000393282, ENST00000413594, ENST00000424319, ENST00000524473, ENST00000525196, ENST00000525278, ENST00000527626, ENST00000527956, ENST00000528341, ENST00000529343, ENST00000531342, ENST00000532825, ENST00000534731, ENST00000535633, ENST00000542487
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597306395GWAS1402469_Hpulse pressure measurement QTL GWAS1402469 (human)5e-41arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
406893379GWAS542355_Hpulse pressure measurement QTL GWAS542355 (human)2e-30arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
597319836GWAS1415910_Hdiastolic blood pressure, systolic blood pressure QTL GWAS1415910 (human)2e-08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118950467889504679Human
597159965GWAS1256039_Hpulse pressure measurement QTL GWAS1256039 (human)1e-11arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118949128589491286Human
407023177GWAS672153_Hhomocysteine measurement QTL GWAS672153 (human)2e-20blood homocysteine amount (VT:0006076)118941520489415205Human
597164181GWAS1260255_Hlipid measurement QTL GWAS1260255 (human)0.000001lipid amount (VT:0001547)blood lipid measurement (CMO:0000050)118935447589354476Human
406905550GWAS554526_Hpulse pressure measurement QTL GWAS554526 (human)9e-22arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
597607568GWAS1664428_Hsystolic blood pressure QTL GWAS1664428 (human)2e-25arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118949128589491286Human
406919630GWAS568606_Hdiastolic blood pressure QTL GWAS568606 (human)2e-11arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)118949130989491310Human
597247126GWAS1343200_Htriglyceride measurement QTL GWAS1343200 (human)0.0000003triglyceride amount (VT:0000187)blood triglyceride level (CMO:0000118)118949155089491551Human
596953222GWAS1072741_Hsize QTL GWAS1072741 (human)1e-12size118957248189572482Human
407023188GWAS672164_Hhomocysteine measurement QTL GWAS672164 (human)2e-08blood homocysteine amount (VT:0006076)118946845989468460Human
596976642GWAS1096161_Hbody height QTL GWAS1096161 (human)6e-10body height118934615389346154Human
597040527GWAS1136601_Hsoluble triggering receptor expressed on myeloid cells 2 measurement QTL GWAS1136601 (human)4e-12soluble triggering receptor expressed on myeloid cells 2 measurement118934181889341819Human
597212422GWAS1308496_Hhealth literacy measurement QTL GWAS1308496 (human)0.000005health literacy measurement118947568689475687Human
597099400GWAS1195474_Hbody mass index QTL GWAS1195474 (human)5e-09body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)118937140589371406Human
406916321GWAS565297_Hsystolic blood pressure QTL GWAS565297 (human)1e-09arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118948325789483258Human
406931937GWAS580913_Hsystolic blood pressure QTL GWAS580913 (human)9e-08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118944949889449499Human
407047782GWAS696758_Htriacylglycerol 52:2 measurement QTL GWAS696758 (human)0.000006blood triglyceride amount (VT:0002644)118948705489487055Human
597048112GWAS1144186_Hsuntan QTL GWAS1144186 (human)3e-23suntan118946454489464545Human
597421617GWAS1517691_Hsystolic blood pressure QTL GWAS1517691 (human)4e-11arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118949130989491310Human
597265205GWAS1361279_Hinsomnia QTL GWAS1361279 (human)2e-08sleep behavior trait (VT:0001501)118941194989411950Human
597267892GWAS1363966_Haortic measurement QTL GWAS1363966 (human)2e-08aortic measurementaorta measurement (CMO:0001474)118949128589491286Human
597062584GWAS1158658_Hpulse pressure measurement QTL GWAS1158658 (human)3e-09arterial blood pressure trait (VT:2000000)aorta measurement (CMO:0001474)118949128589491286Human
597137958GWAS1234032_Hdiastolic blood pressure, systolic blood pressure QTL GWAS1234032 (human)0.000004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118950467889504679Human
597064228GWAS1160302_Hpulse pressure measurement QTL GWAS1160302 (human)9e-16arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
406999162GWAS648138_Hadolescent idiopathic scoliosis QTL GWAS648138 (human)4e-38adolescent idiopathic scoliosis118942118689421187Human
597053742GWAS1149816_Hsunburn QTL GWAS1149816 (human)2e-09sunburn118945229389452294Human
597129519GWAS1225593_Hpulse pressure measurement QTL GWAS1225593 (human)1e-65arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
596974383GWAS1093902_Hvitamin D measurement QTL GWAS1093902 (human)2e-10vitamin D measurement118935263389352634Human
597102765GWAS1198839_Hgut microbiome measurement QTL GWAS1198839 (human)0.000008gut microbiome measurement118946770589467706Human
597129517GWAS1225591_Hpulse pressure measurement QTL GWAS1225591 (human)5e-29arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118946562889465629Human
597021865GWAS1117939_HTNF-related apoptosis-inducing ligand measurement QTL GWAS1117939 (human)0.000005TNF-related apoptosis-inducing ligand measurement118952704589527046Human
597161387GWAS1257461_Hlipid measurement QTL GWAS1257461 (human)0.000009lipid amount (VT:0001547)blood lipid measurement (CMO:0000050)118935447589354476Human
406931964GWAS580940_Hpulse pressure measurement QTL GWAS580940 (human)1e-16arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118944949889449499Human
597585953GWAS1642813_Hdiastolic blood pressure change measurement QTL GWAS1642813 (human)1e-14arterial blood pressure trait (VT:2000000)change in diastolic blood pressure (CMO:0001016)118949130989491310Human
597581790GWAS1638650_Hpulse pressure measurement QTL GWAS1638650 (human)5e-12arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118946562889465629Human
597581791GWAS1638651_Hpulse pressure measurement QTL GWAS1638651 (human)6e-35arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949130989491310Human
597319378GWAS1415452_Hopioid dependence QTL GWAS1415452 (human)0.000004response to addictive substance trait (VT:0010488)118941540389415404Human
597591252GWAS1648112_Hprotozoa infectious disease QTL GWAS1648112 (human)3e-11protozoa infectious disease118951635489516355Human
597616597GWAS1673457_HGenu varum, Genu valgum QTL GWAS1673457 (human)2e-11Genu varum, Genu valgum118934495189344952Human
597037658GWAS1133732_Hpulse pressure measurement QTL GWAS1133732 (human)2e-11arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
406901006GWAS549982_Hsystolic blood pressure QTL GWAS549982 (human)2e-09arterial blood pressure trait (VT:2000000)blood aspartate aminotransferase activity level (CMO:0000580)118949128589491286Human
407042704GWAS691680_Hhomocysteine measurement QTL GWAS691680 (human)0.000008blood homocysteine amount (VT:0006076)118937948289379483Human
597125443GWAS1221517_Hhomocysteine measurement QTL GWAS1221517 (human)2e-08blood homocysteine amount (VT:0006076)118940531789405318Human
597125442GWAS1221516_Hhomocysteine measurement QTL GWAS1221516 (human)3e-09blood homocysteine amount (VT:0006076)118945942089459421Human
597411781GWAS1507855_Hpulse pressure measurement QTL GWAS1507855 (human)0.0000009arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949525789495258Human
597097207GWAS1193281_Hdiabetic retinopathy QTL GWAS1193281 (human)4e-09retina integrity trait (VT:0010771)118936358989363590Human
597202681GWAS1298755_Hdiastolic blood pressure QTL GWAS1298755 (human)8e-09arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)118949128589491286Human
407073703GWAS722679_Hpulse pressure measurement QTL GWAS722679 (human)1e-28arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
597042928GWAS1139002_Htriglyceride measurement QTL GWAS1139002 (human)0.0000008triglyceride amount (VT:0000187)blood triglyceride level (CMO:0000118)118949155089491551Human
597066736GWAS1162810_Hsusceptibility to mumps measurement QTL GWAS1162810 (human)0.000005response to viral infection trait (VT:0010439)118947251289472513Human
597166846GWAS1262920_Hbody weight QTL GWAS1262920 (human)1e-08aorta integrity trait (VT:0010602)body weight (CMO:0000012)118949155089491551Human
597141757GWAS1237831_Hcystine measurement QTL GWAS1237831 (human)6e-19cystine measurement118935263389352634Human
597027198GWAS1123272_Hsystolic blood pressure QTL GWAS1123272 (human)0.000004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118949128589491286Human
406898605GWAS547581_Hpulse pressure measurement QTL GWAS547581 (human)1e-10arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
597615475GWAS1672335_Hsystolic blood pressure QTL GWAS1672335 (human)2e-19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118949128589491286Human
406898607GWAS547583_Hpulse pressure measurement QTL GWAS547583 (human)1e-14arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human
597591793GWAS1648653_Hskin disease QTL GWAS1648653 (human)5e-18skin disease118932493389324934Human
597270634GWAS1366708_Hpulse pressure measurement QTL GWAS1366708 (human)5e-17arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949076389490764Human
597270636GWAS1366710_Hpulse pressure measurement QTL GWAS1366710 (human)3e-16arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118946562889465629Human
597344879GWAS1440953_Hbody mass index QTL GWAS1440953 (human)5e-10body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)118934258689342587Human
597100911GWAS1196985_Hprotein measurement QTL GWAS1196985 (human)1e-08protein amount (VT:0010120)118936255389362554Human
597347808GWAS1443882_Hsystolic blood pressure QTL GWAS1443882 (human)4e-12arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118946562889465629Human
597347809GWAS1443883_Hsystolic blood pressure QTL GWAS1443883 (human)5e-18arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)118949128589491286Human
597072104GWAS1168178_Hpulse pressure measurement QTL GWAS1168178 (human)5e-12arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)118949128589491286Human

Markers in Region
D11S1326  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371149,324,506 - 49,324,756UniSTSGRCh37
GRCh371149,324,664 - 49,324,774UniSTSGRCh37
GRCh371189,138,204 - 89,138,314UniSTSGRCh37
GRCh371189,138,222 - 89,138,472UniSTSGRCh37
Build 361149,281,082 - 49,281,332RGDNCBI36
Celera1185,493,623 - 85,493,741UniSTS
Celera1149,475,503 - 49,475,613UniSTS
Celera1149,475,345 - 49,475,595RGD
Celera1185,493,465 - 85,493,723UniSTS
Cytogenetic Map11q14.2-q21UniSTS
HuRef1185,375,356 - 85,375,606UniSTS
HuRef1185,375,338 - 85,375,448UniSTS
HuRef1149,042,572 - 49,042,818UniSTS
HuRef1149,042,730 - 49,042,836UniSTS
Marshfield Genetic Map1158.4UniSTS
Marshfield Genetic Map1158.4RGD
Genethon Genetic Map1162.5UniSTS
TNG Radiation Hybrid Map1140964.0UniSTS
deCODE Assembly Map1163.81UniSTS
RH92457  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371189,059,579 - 89,059,743UniSTSGRCh37
GRCh371149,401,225 - 49,401,389UniSTSGRCh37
Build 361149,357,801 - 49,357,965RGDNCBI36
Celera1185,572,196 - 85,572,360UniSTS
Celera1149,552,062 - 49,552,226RGD
Cytogenetic Map11q14.2-q21UniSTS
Cytogenetic Map11p11.12UniSTS
HuRef1185,296,695 - 85,296,859UniSTS
HuRef1149,119,296 - 49,119,460UniSTS
D11S3741  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371189,078,463 - 89,078,747UniSTSGRCh37
GRCh371149,382,234 - 49,382,518UniSTSGRCh37
Build 361149,338,810 - 49,339,094RGDNCBI36
Celera1185,553,200 - 85,553,484UniSTS
Celera1149,533,070 - 49,533,354RGD
Cytogenetic Map11q14.2-q21UniSTS
Cytogenetic Map11p11.12UniSTS
HuRef1185,315,574 - 85,315,858UniSTS
HuRef1149,100,307 - 49,100,591UniSTS
NOX4_8033  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371149,400,971 - 49,401,560UniSTSGRCh37
GRCh371189,059,408 - 89,059,996UniSTSGRCh37
Build 361149,357,547 - 49,358,136RGDNCBI36
Celera1149,551,808 - 49,552,397RGD
Celera1185,571,943 - 85,572,531UniSTS
HuRef1185,296,524 - 85,297,112UniSTS
HuRef1149,119,042 - 49,119,631UniSTS
G35510  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q21UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map1q42UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map13q12.11UniSTS
Cytogenetic Map10p12UniSTS
Cytogenetic Map9q13-q21UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map20q11.2-q13.2UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic MapXp22UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map2p25-p24UniSTS
Cytogenetic Map16pUniSTS
Cytogenetic Map4q21.3UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map12q24.31-q24.32UniSTS
Cytogenetic Map1p35UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic MapXp11UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map9p12UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map14q13.2UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map6pter-q22.33UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic Map9q21.33UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map11q14.2-q21UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic Map3q28UniSTS
Cytogenetic Map9p21.3UniSTS
Cytogenetic Map7p15.1UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map5q31-q32UniSTS
Cytogenetic Map18p11.2UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map12p13.33UniSTS
Cytogenetic Map18p11.22-p11.21UniSTS
Cytogenetic Map5q34-q35UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map2p25.3UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map12q23.3UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map9q21.11UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map17q24.3UniSTS
Cytogenetic Map7p14.2UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map1p36.2UniSTS
Cytogenetic Map12q14.1UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map11q13.3UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map5q35.2UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map10q26.1UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map12q13.1-q13.2UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map1q42.3UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic MapXp22.32UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map1q23.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map6pter-p12.1UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map17pUniSTS
Cytogenetic Map3p26UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map20q13.33UniSTS
D11S1326  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11q14.2-q21UniSTS
TNG Radiation Hybrid Map1140964.0UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2332 2787 2232 4860 1658 2177 5 564 1005 402 2251 6195 5519 34 3644 820 1693 1508 166 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001143836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001300995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_016931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_120406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006718849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011542857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017017841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017017842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017017843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017017844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017017845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054369008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB041035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF254621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF261943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ704725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ704726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ704727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ704728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ704729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK057189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK311381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK311389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP002404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP003400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW207163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY288918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP376400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU730205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA970477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF455439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF455440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000263317   ⟹   ENSP00000263317
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,324,353 - 89,491,375 (-)Ensembl
Ensembl Acc Id: ENST00000343727   ⟹   ENSP00000344747
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,325,368 - 89,491,131 (-)Ensembl
Ensembl Acc Id: ENST00000375979   ⟹   ENSP00000365146
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,756 - 89,491,246 (-)Ensembl
Ensembl Acc Id: ENST00000393282   ⟹   ENSP00000376961
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,488,906 - 89,491,565 (-)Ensembl
Ensembl Acc Id: ENST00000424319   ⟹   ENSP00000412446
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,324,356 - 89,492,224 (-)Ensembl
Ensembl Acc Id: ENST00000524473
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,361 - 89,336,083 (-)Ensembl
Ensembl Acc Id: ENST00000525196   ⟹   ENSP00000436716
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,344 - 89,491,360 (-)Ensembl
Ensembl Acc Id: ENST00000525278
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,443,421 - 89,491,394 (-)Ensembl
Ensembl Acc Id: ENST00000527626   ⟹   ENSP00000436093
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,416 - 89,491,328 (-)Ensembl
Ensembl Acc Id: ENST00000527956   ⟹   ENSP00000433797
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,347 - 89,498,187 (-)Ensembl
Ensembl Acc Id: ENST00000528341   ⟹   ENSP00000436970
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,567 - 89,490,732 (-)Ensembl
Ensembl Acc Id: ENST00000529343   ⟹   ENSP00000435474
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,756 - 89,491,357 (-)Ensembl
Ensembl Acc Id: ENST00000531342   ⟹   ENSP00000435039
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,756 - 89,491,246 (-)Ensembl
Ensembl Acc Id: ENST00000532825   ⟹   ENSP00000434924
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,347 - 89,492,190 (-)Ensembl
Ensembl Acc Id: ENST00000534731   ⟹   ENSP00000436892
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1189,326,299 - 89,491,328 (-)Ensembl
RefSeq Acc Id: NM_001143836   ⟹   NP_001137308
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,324,353 - 89,491,375 (-)NCBI
GRCh371189,057,521 - 89,322,779 (-)NCBI
HuRef1185,294,642 - 85,559,923 (-)NCBI
CHM1_11188,940,465 - 89,107,736 (-)NCBI
T2T-CHM13v2.01189,244,014 - 89,411,075 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143837   ⟹   NP_001137309
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,324,353 - 89,589,557 (-)NCBI
GRCh371189,057,521 - 89,322,779 (-)NCBI
HuRef1185,294,642 - 85,559,923 (-)NCBI
CHM1_11188,940,465 - 89,205,767 (-)NCBI
T2T-CHM13v2.01189,244,014 - 89,509,286 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001291926   ⟹   NP_001278855
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,324,353 - 89,491,375 (-)NCBI
CHM1_11188,940,465 - 89,107,736 (-)NCBI
T2T-CHM13v2.01189,244,014 - 89,411,075 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001291927   ⟹   NP_001278856
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,324,353 - 89,490,978 (-)NCBI
CHM1_11188,940,465 - 89,107,148 (-)NCBI
T2T-CHM13v2.01189,244,014 - 89,410,677 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001291929   ⟹   NP_001278858
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,324,353 - 89,490,760 (-)NCBI
CHM1_11188,940,465 - 89,106,908 (-)NCBI
T2T-CHM13v2.01189,244,014 - 89,410,456 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001300995   ⟹   NP_001287924
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,324,353 - 89,492,219 (-)NCBI
CHM1_11188,940,465 - 89,108,391 (-)NCBI
T2T-CHM13v2.01189,244,014 - 89,411,920 (-)NCBI
Sequence:
RefSeq Acc Id: NM_016931   ⟹   NP_058627
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,324,353 - 89,491,375 (-)NCBI
GRCh371189,057,521 - 89,322,779 (-)NCBI
Build 361188,699,160 - 88,864,301 (-)NCBI Archive
HuRef1185,294,642 - 85,559,923 (-)NCBI
CHM1_11188,940,465 - 89,107,736 (-)NCBI
T2T-CHM13v2.01189,244,014 - 89,411,075 (-)NCBI
Sequence:
RefSeq Acc Id: NR_120406
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,488,849 - 89,491,375 (-)NCBI
CHM1_11189,105,020 - 89,107,736 (-)NCBI
T2T-CHM13v2.01189,408,544 - 89,411,075 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017017843   ⟹   XP_016873332
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,355,028 - 89,490,978 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054369008   ⟹   XP_054224983
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01189,274,688 - 89,410,677 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001137308 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137309 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278855 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278856 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278858 (Get FASTA)   NCBI Sequence Viewer  
  NP_001287924 (Get FASTA)   NCBI Sequence Viewer  
  NP_058627 (Get FASTA)   NCBI Sequence Viewer  
  XP_016873332 (Get FASTA)   NCBI Sequence Viewer  
  XP_054224983 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF68973 (Get FASTA)   NCBI Sequence Viewer  
  AAF87572 (Get FASTA)   NCBI Sequence Viewer  
  AAH40105 (Get FASTA)   NCBI Sequence Viewer  
  AAH51371 (Get FASTA)   NCBI Sequence Viewer  
  AAP41109 (Get FASTA)   NCBI Sequence Viewer  
  BAA95695 (Get FASTA)   NCBI Sequence Viewer  
  BAF84519 (Get FASTA)   NCBI Sequence Viewer  
  BAG51879 (Get FASTA)   NCBI Sequence Viewer  
  BAH12756 (Get FASTA)   NCBI Sequence Viewer  
  BAH12759 (Get FASTA)   NCBI Sequence Viewer  
  BAH12765 (Get FASTA)   NCBI Sequence Viewer  
  BAH12771 (Get FASTA)   NCBI Sequence Viewer  
  CAG28807 (Get FASTA)   NCBI Sequence Viewer  
  CAG28808 (Get FASTA)   NCBI Sequence Viewer  
  CAG28809 (Get FASTA)   NCBI Sequence Viewer  
  CAG28810 (Get FASTA)   NCBI Sequence Viewer  
  CAG28811 (Get FASTA)   NCBI Sequence Viewer  
  EAW59353 (Get FASTA)   NCBI Sequence Viewer  
  EAW59354 (Get FASTA)   NCBI Sequence Viewer  
  EAW59355 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000263317
  ENSP00000263317.4
  ENSP00000344747.5
  ENSP00000365146.3
  ENSP00000376961.2
  ENSP00000412446
  ENSP00000412446.1
  ENSP00000433797.1
  ENSP00000434924
  ENSP00000434924.1
  ENSP00000435039.1
  ENSP00000435474.1
  ENSP00000436892
  ENSP00000436892.1
  ENSP00000436970
GenBank Protein Q9NPH5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001137309   ⟸   NM_001143837
- Peptide Label: isoform c
- UniProtKB: B3KQ17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137308   ⟸   NM_001143836
- Peptide Label: isoform b
- UniProtKB: B3KQ17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_058627   ⟸   NM_016931
- Peptide Label: isoform a
- UniProtKB: Q9NPH5 (UniProtKB/Swiss-Prot),   Q7Z7G3 (UniProtKB/Swiss-Prot),   Q5K3R8 (UniProtKB/Swiss-Prot),   Q5K3R6 (UniProtKB/Swiss-Prot),   Q5K3R5 (UniProtKB/Swiss-Prot),   Q5K3R4 (UniProtKB/Swiss-Prot),   E7EMD7 (UniProtKB/Swiss-Prot),   B7Z520 (UniProtKB/Swiss-Prot),   A8K715 (UniProtKB/Swiss-Prot),   Q86V92 (UniProtKB/Swiss-Prot),   B3KQ17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001287924   ⟸   NM_001300995
- Peptide Label: isoform g
- UniProtKB: B3KQ17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278855   ⟸   NM_001291926
- Peptide Label: isoform d
- UniProtKB: B7Z529 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278856   ⟸   NM_001291927
- Peptide Label: isoform e
- UniProtKB: B7Z523 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278858   ⟸   NM_001291929
- Peptide Label: isoform f
- UniProtKB: E9PPP2 (UniProtKB/TrEMBL),   B7Z529 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016873332   ⟸   XM_017017843
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSP00000412446   ⟸   ENST00000424319
Ensembl Acc Id: ENSP00000435039   ⟸   ENST00000531342
Ensembl Acc Id: ENSP00000365146   ⟸   ENST00000375979
Ensembl Acc Id: ENSP00000434924   ⟸   ENST00000532825
Ensembl Acc Id: ENSP00000436892   ⟸   ENST00000534731
Ensembl Acc Id: ENSP00000436716   ⟸   ENST00000525196
Ensembl Acc Id: ENSP00000376961   ⟸   ENST00000393282
Ensembl Acc Id: ENSP00000263317   ⟸   ENST00000263317
Ensembl Acc Id: ENSP00000433797   ⟸   ENST00000527956
Ensembl Acc Id: ENSP00000436093   ⟸   ENST00000527626
Ensembl Acc Id: ENSP00000436970   ⟸   ENST00000528341
Ensembl Acc Id: ENSP00000344747   ⟸   ENST00000343727
Ensembl Acc Id: ENSP00000435474   ⟸   ENST00000529343
RefSeq Acc Id: XP_054224983   ⟸   XM_054369008
- Peptide Label: isoform X1
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NPH5-F1-model_v2 AlphaFold Q9NPH5 1-578 view protein structure

Promoters
RGD ID:7221785
Promoter ID:EPDNEW_H16638
Type:initiation region
Name:NOX4_2
Description:NADPH oxidase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16639  EPDNEW_H16640  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,491,273 - 89,491,333EPDNEW
RGD ID:7221787
Promoter ID:EPDNEW_H16639
Type:initiation region
Name:NOX4_1
Description:NADPH oxidase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16638  EPDNEW_H16640  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,491,375 - 89,491,435EPDNEW
RGD ID:7221789
Promoter ID:EPDNEW_H16640
Type:initiation region
Name:NOX4_3
Description:NADPH oxidase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16638  EPDNEW_H16639  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381189,491,508 - 89,491,568EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:7891 AgrOrtholog
COSMIC NOX4 COSMIC
Ensembl Genes ENSG00000086991 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000263317 ENTREZGENE
  ENST00000263317.9 UniProtKB/Swiss-Prot
  ENST00000343727.9 UniProtKB/Swiss-Prot
  ENST00000375979.7 UniProtKB/Swiss-Prot
  ENST00000393282.2 UniProtKB/Swiss-Prot
  ENST00000424319 ENTREZGENE
  ENST00000424319.5 UniProtKB/Swiss-Prot
  ENST00000527956.5 UniProtKB/Swiss-Prot
  ENST00000528341 ENTREZGENE
  ENST00000529343.5 UniProtKB/Swiss-Prot
  ENST00000531342.5 UniProtKB/Swiss-Prot
  ENST00000532825 ENTREZGENE
  ENST00000532825.5 UniProtKB/Swiss-Prot
  ENST00000534731 ENTREZGENE
  ENST00000534731.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.80 UniProtKB/Swiss-Prot
  Translation factors UniProtKB/Swiss-Prot
GTEx ENSG00000086991 GTEx
HGNC ID HGNC:7891 ENTREZGENE
Human Proteome Map NOX4 Human Proteome Map
InterPro Cyt_b245_heavy_chain UniProtKB/Swiss-Prot
  FAD-bd_8 UniProtKB/Swiss-Prot
  FAD-bd_FR_type UniProtKB/Swiss-Prot
  Fe3_Rdtase_TM_dom UniProtKB/Swiss-Prot
  Fe_red_NAD-bd_6 UniProtKB/Swiss-Prot
  FNR_nucleotide-bd UniProtKB/Swiss-Prot
  RBOH/FRE UniProtKB/Swiss-Prot
  Riboflavin_synthase-like_b-brl UniProtKB/Swiss-Prot
KEGG Report hsa:50507 UniProtKB/Swiss-Prot
NCBI Gene 50507 ENTREZGENE
OMIM 605261 OMIM
PANTHER NADPH OXIDASE UniProtKB/Swiss-Prot
  NADPH OXIDASE 4 UniProtKB/Swiss-Prot
Pfam FAD_binding_8 UniProtKB/Swiss-Prot
  Ferric_reduct UniProtKB/Swiss-Prot
  NAD_binding_6 UniProtKB/Swiss-Prot
PharmGKB PA31692 PharmGKB
PRINTS GP91PHOX UniProtKB/Swiss-Prot
PROSITE FAD_FR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52343 UniProtKB/Swiss-Prot
  SSF63380 UniProtKB/Swiss-Prot
UniProt A8K715 ENTREZGENE
  B3KQ17 ENTREZGENE, UniProtKB/TrEMBL
  B7Z520 ENTREZGENE
  B7Z523 ENTREZGENE, UniProtKB/TrEMBL
  B7Z529 ENTREZGENE, UniProtKB/TrEMBL
  E7EMD7 ENTREZGENE
  E9PI95_HUMAN UniProtKB/TrEMBL
  E9PPP2 ENTREZGENE, UniProtKB/TrEMBL
  E9PR43_HUMAN UniProtKB/TrEMBL
  NOX4_HUMAN UniProtKB/Swiss-Prot
  Q5K3R4 ENTREZGENE
  Q5K3R5 ENTREZGENE
  Q5K3R6 ENTREZGENE
  Q5K3R8 ENTREZGENE
  Q7Z7G3 ENTREZGENE
  Q86V92 ENTREZGENE
  Q9NPH5 ENTREZGENE
UniProt Secondary A8K715 UniProtKB/Swiss-Prot
  B7Z520 UniProtKB/Swiss-Prot
  E7EMD7 UniProtKB/Swiss-Prot
  Q5K3R4 UniProtKB/Swiss-Prot
  Q5K3R5 UniProtKB/Swiss-Prot
  Q5K3R6 UniProtKB/Swiss-Prot
  Q5K3R8 UniProtKB/Swiss-Prot
  Q7Z7G3 UniProtKB/Swiss-Prot
  Q86V92 UniProtKB/Swiss-Prot