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Gene: PARK7 (Parkinsonism associated deglycase) Homo sapiens
Symbol: PARK7
Name: Parkinsonism associated deglycase
RGD ID: 1344212
Description: Exhibits several functions, including enzyme binding activity; molecular function regulator; and transition metal ion binding activity. Involved in several processes, including negative regulation of apoptotic signaling pathway; protein deglycation; and regulation of cellular protein metabolic process. Localizes to several cellular components, including PML body; endoplasmic reticulum; and perinuclear region of cytoplasm. Implicated in Parkinson's disease; Parkinson's disease 7; cerebral infarction; and middle cerebral artery infarction.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DJ-1; DJ1; epididymis secretory sperm binding protein Li 67p; FLJ27376; FLJ34360; FLJ92274; GATD2; HEL-S-67p; maillard deglycase; oncogene DJ1; Parkinson disease (autosomal recessive, early onset) 7; Parkinson disease protein 7; parkinson protein 7; protein/nucleic acid deglycase DJ-1
Mus musculus (house mouse) : Park7 (Parkinson disease (autosomal recessive, early onset) 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Park7 (Parkinsonism associated deglycase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Park7 (Parkinsonism associated deglycase)
Pan paniscus (bonobo/pygmy chimpanzee) : PARK7 (Parkinsonism associated deglycase)
Canis lupus familiaris (dog) : PARK7 (Parkinsonism associated deglycase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Park7 (Parkinsonism associated deglycase)
Sus scrofa (pig) : PARK7 (Parkinsonism associated deglycase)
Chlorocebus sabaeus (African green monkey) : PARK7 (Parkinsonism associated deglycase)
Heterocephalus glaber (naked mole-rat) : Park7 (Parkinsonism associated deglycase)
more info ...
Related Pseudogenes: PARK7P1   PARK7P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl17,954,291 - 7,985,505 (+)EnsemblGRCh38hg38GRCh38
GRCh3817,961,711 - 7,985,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3718,021,714 - 8,045,342 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3617,944,380 - 7,967,926 (+)NCBINCBI36hg18NCBI36
Build 3417,956,058 - 7,979,602NCBI
Celera17,128,771 - 7,152,398 (+)NCBI
Cytogenetic Map1p36.23NCBI
HuRef17,169,316 - 7,193,163 (+)NCBIHuRef
CHM1_118,009,469 - 8,033,097 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PARK7
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344212
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.