Park7 (Parkinsonism associated deglycase)

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Gene: Park7 (Parkinsonism associated deglycase) Ictidomys tridecemlineatus

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Symbol:

Park7

Name:

Parkinsonism associated deglycase

RGD ID:

12649986

Description:

ENCODES a protein that exhibits double-stranded DNA binding (ortholog); protein deglycase activity (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN adult locomotory behavior (ortholog); cellular response to hypoxia (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIPATES IN Parkinson's disease pathway; transforming growth factor-beta signaling pathway; ASSOCIATED WITH amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 (ortholog); cerebral infarction (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN axon (ortholog); sperm head (ortholog); synaptic vesicle (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Parkinson disease protein 7; Parkinsonism associated deglycase, transcript variant X1; Parkinsonism associated deglycase, transcript variant X2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	31,937,508 - 31,951,577 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936623	2,422,833 - 2,436,817 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936623	2,422,780 - 2,436,817 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 (ISO)

cerebral infarction (ISO)

Chemical and Drug Induced Liver Injury (ISO)

chromosome 1p36 deletion syndrome (ISO)

early-onset Parkinson's disease (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

juvenile-onset Parkinson's disease (ISO)

late onset Parkinson's disease (ISO)

maturity-onset diabetes of the young type 5 (ISO)

middle cerebral artery infarction (ISO)

motor neuron disease (ISO)

Nerve Degeneration (ISO)

Neurodevelopmental Disorders (ISO)

osteoporosis (ISO)

Parkinson's disease (ISO)

Parkinson's disease 2 (ISO)

Parkinson's disease 6 (ISO)

Parkinson's disease 7 (ISO)

Parkinsonism (ISO)

perinatal necrotizing enterocolitis (ISO)

Pulmonary Arterial Hypertension (ISO)

Reticulocytosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult locomotory behavior (IEA,ISO)

androgen receptor signaling pathway (IEA)

cellular detoxification of aldehyde (IEA)

cellular detoxification of methylglyoxal (IEA)

cellular response to glyoxal (IEA)

cellular response to hydrogen peroxide (IEA)

cellular response to hypoxia (ISO)

cellular response to lipopolysaccharide (ISO)

cellular response to oxidative stress (IEA)

cellular response to reactive oxygen species (IEA,ISO)

detection of oxidative stress (IEA)

detoxification of copper ion (IEA)

detoxification of hydrogen peroxide (IEA)

detoxification of mercury ion (IEA)

DNA repair (IEA)

dopamine uptake involved in synaptic transmission (IEA,ISO)

glucose homeostasis (IEA)

glycolate biosynthetic process (IEA)

glyoxal catabolic process (IEA)

glyoxal metabolic process (IEA)

guanine deglycation (IEA)

guanine deglycation, glyoxal removal (IEA)

guanine deglycation, methylglyoxal removal (IEA)

hydrogen peroxide metabolic process (IEA,ISO)

insulin secretion (IEA)

lactate biosynthetic process (IEA)

maternal process involved in female pregnancy (ISO)

membrane depolarization (IEA,ISO)

membrane hyperpolarization (IEA,ISO)

methylglyoxal catabolic process to lactate (IEA)

methylglyoxal metabolic process (IEA,ISO)

mitochondrion organization (IEA)

negative regulation of cellular process (ISO)

negative regulation of death-inducing signaling complex assembly (IEA)

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (IEA)

negative regulation of extrinsic apoptotic signaling pathway (IEA)

negative regulation of gene expression (IEA)

negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway (IEA)

negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (IEA)

negative regulation of neuron apoptotic process (IEA)

negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway (IEA)

negative regulation of NMDA glutamate receptor activity (ISO)

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (IEA,ISO)

negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway (IEA)

negative regulation of proteasomal ubiquitin-dependent protein catabolic process (IEA,ISO)

negative regulation of protein acetylation (IEA)

negative regulation of protein catabolic process (IEA)

negative regulation of protein export from nucleus (IEA)

negative regulation of protein K48-linked deubiquitination (IEA)

negative regulation of protein phosphorylation (ISO)

negative regulation of protein sumoylation (IEA)

negative regulation of protein ubiquitination (IEA,ISO)

negative regulation of reactive oxygen species biosynthetic process (IEA)

negative regulation of smooth muscle cell migration (ISO)

negative regulation of TRAIL-activated apoptotic signaling pathway (IEA)

negative regulation of vascular associated smooth muscle cell proliferation (ISO)

positive regulation of acute inflammatory response to antigenic stimulus (IEA)

positive regulation of dopamine biosynthetic process (IEA)

positive regulation of fertilization (ISO)

positive regulation of gene expression (IEA)

positive regulation of interleukin-8 production (IEA,ISO)

positive regulation of L-dopa biosynthetic process (IEA,ISO)

positive regulation of mitochondrial electron transport, NADH to ubiquinone (IEA)

positive regulation of NAD(P)H oxidase activity (ISO)

positive regulation of oxidative phosphorylation uncoupler activity (ISO)

positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (IEA,ISO)

positive regulation of peptidyl-serine phosphorylation (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA)

positive regulation of protein localization to nucleus (IEA)

positive regulation of protein-containing complex assembly (IEA)

positive regulation of reactive oxygen species biosynthetic process (IEA,ISO)

positive regulation of reactive oxygen species metabolic process (IEA)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

protein repair (IEA)

protein stabilization (IEA,ISO)

proteolysis (IEA)

regulation of androgen receptor signaling pathway (IEA)

regulation of inflammatory response (IEA)

regulation of mitochondrial membrane potential (IEA)

regulation of neuron apoptotic process (IEA)

regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway (IEA)

regulation of synaptic vesicle endocytosis (IEA)

regulation of TRAIL production (ISO)

removal of superoxide radicals (IEA)

response to hydrogen peroxide (IEA,ISO)

response to oxidative stress (IEA,ISO)

response to xenobiotic stimulus (ISO)

single fertilization (IEA)

spermatogenesis (ISO)

synaptic transmission, dopaminergic (IEA,ISO)

Cellular Component

axon (ISO)

cell body (IEA)

chromatin (IEA)

cytoplasm (IEA)

cytosol (IEA)

endoplasmic reticulum (IEA)

membrane raft (IEA)

mitochondrial intermembrane space (IEA)

mitochondrial matrix (IEA)

mitochondrion (IEA)

neuron projection (IEA)

nucleoplasm (IEA)

nucleus (IEA)

perinuclear region of cytoplasm (IEA)

PML body (IEA)

sperm head (ISO)

synaptic vesicle (IEA,ISO)

Molecular Function

copper ion binding (IEA)

cupric ion binding (IEA)

cuprous ion binding (IEA)

cytokine binding (IEA)

DNA-binding transcription factor binding (IEA)

double-stranded DNA binding (ISO)

enzyme activator activity (IEA)

enzyme binding (IEA)

glyoxalase (glycolic acid-forming) activity (IEA)

identical protein binding (IEA)

kinase binding (IEA)

L-dopa decarboxylase activator activity (IEA)

mercury ion binding (IEA)

mRNA binding (IEA)

nuclear androgen receptor binding (IEA)

oxidoreductase activity, acting on peroxide as acceptor (IEA)

oxygen sensor activity (IEA)

peptidase activity (IEA)

peptidase inhibitor activity (IEA)

peroxiredoxin activity (IEA)

protein binding (ISO)

protein deglycase activity (IEA,ISO)

protein homodimerization activity (IEA)

scaffold protein binding (IEA)

signaling receptor activator activity (IEA)

signaling receptor binding (IEA)

single-stranded DNA binding (ISO)

small protein activating enzyme binding (IEA)

superoxide dismutase copper chaperone activity (IEA)

transcription coactivator activity (IEA)

tyrosine 3-monooxygenase activator activity (IEA)

ubiquitin-like protein conjugating enzyme binding (IEA)

ubiquitin-protein transferase inhibitor activity (IEA)

ubiquitin-specific protease binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

Parkinson's disease pathway (ISO)

transforming growth factor-beta signaling pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Park7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	31,937,508 - 31,951,577 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936623	2,422,833 - 2,436,817 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936623	2,422,780 - 2,436,817 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PARK7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	7,961,711 - 7,985,505 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	7,954,291 - 7,985,505 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	8,021,771 - 8,045,565 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	7,944,380 - 7,967,926 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	7,956,058 - 7,979,602	NCBI
Celera	1	7,128,771 - 7,152,398 (+)	NCBI		Celera
Cytogenetic Map	1	p36.23	NCBI
HuRef	1	7,169,316 - 7,193,163 (+)	NCBI		HuRef
CHM1_1	1	8,009,469 - 8,033,097 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	7,492,675 - 7,516,444 (+)	NCBI		T2T-CHM13v2.0

Park7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	150,981,590 - 150,994,378 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	150,981,590 - 150,998,894 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	150,897,133 - 150,909,921 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	150,897,133 - 150,914,437 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	150,271,242 - 150,284,030 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	149,740,942 - 149,753,650 (-)	NCBI		MGSCv36	mm8
Celera	4	153,174,297 - 153,187,100 (-)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	81.52	NCBI

Park7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	166,636,551 - 166,659,825 (-)	NCBI		GRCr8
mRatBN7.2	5	161,353,718 - 161,376,993 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	161,353,719 - 161,376,970 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	164,071,138 - 164,094,398 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	165,887,564 - 165,910,960 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	165,849,775 - 165,873,035 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	167,982,438 - 168,004,724 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	167,982,439 - 168,004,724 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	171,559,202 - 171,582,476 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	168,050,149 - 168,061,616 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	168,060,336 - 168,071,804 (-)	NCBI
Celera	5	159,607,648 - 159,630,713 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Park7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	4,969,497 - 4,985,885 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	4,974,130 - 4,985,927 (-)	NCBI	ChiLan1.0	ChiLan1.0

PARK7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	220,243,225 - 220,268,293 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	218,884,515 - 218,908,146 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	6,722,260 - 6,745,915 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	7,969,265 - 7,993,271 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	7,969,280 - 7,993,271 (+)	Ensembl	panpan1.1		panPan2

PARK7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	61,576,219 - 61,592,325 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	61,576,069 - 61,592,303 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	61,584,413 - 61,601,125 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	61,791,984 - 61,808,701 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	61,792,439 - 61,808,700 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	61,791,244 - 61,807,961 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	61,656,017 - 61,672,730 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	62,059,399 - 62,076,120 (+)	NCBI		UU_Cfam_GSD_1.0

PARK7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	68,629,214 - 68,645,516 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	68,629,327 - 68,645,147 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	63,023,779 - 63,033,855 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PARK7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	123,776,084 - 123,808,031 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	123,776,297 - 123,798,434 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	27,810,002 - 27,834,129 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Park7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	3,900,917 - 3,911,042 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624818	3,900,917 - 3,915,457 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005334740	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013362623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040287875	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040287876	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000022865 ⟹ ENSSTOP00000022415

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936623	2,422,833 - 2,436,817 (+)	Ensembl

RefSeq Acc Id:

XM_005334740 ⟹ XP_005334797

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	31,937,508 - 31,951,577 (+)	NCBI
SpeTri2.0	NW_004936623	2,422,780 - 2,436,817 (+)	NCBI

Sequence:

show sequence

CCACTGACGCGAGCGGCGCGAGTCTGCGCAGTGCAGCGCCGAGGGCCCGCGGCGCGTGCGTGCT
GGGGTGAGCAGCCTTCGCTCCGCGGGGTGTTAAAACAACATCAAAATGGCTTCAAAAAGAGCCC
TGGTCATCCTGGCCAAAGGAGCAGAGGAGATGGAGACCGTTATCCCTGTGGATGTCATGAGAAG
AGCTGGGATTAAGGTCACGGTTGCAGGTCTGTCTGGAAAAGACCCAGTACAGTGTAGCCGTGAT
GTTGTCATTTGTCCTGATGCCAGTCTTGAAGATGCACGAAAGCAGGGACCATACGATGTGGTGG
TTCTGCCAGGAGGTAATCTGGGTGCACAGAATTTATCTGAGTCTGCTGCTGTGAAGGAGATCCT
GAAGGAGCAGGAGAGCAGGAAGGGCCTCATAGCCGCCATCTGTGCAGGTCCTACGGCTCTTTTG
GCTCATGAAATAGGTTTTGGAAGTAAAGTTACAACACACCCACTTGCTAAAGACAAAATGATGA
ATGGGAGTCACTACAGCTATTCAGAGAGCCGCGTGGAACAGGACGGCCTGATCCTCACCAGCCG
TGGGCCTGGGACCAGCTTTGAGTTCGCCCTTGCCATCGTGGACGCGCTCATGGGCAAGGAGGTG
GCCAACCAGGTGAAGGCGCCCCTGGTTCTTAAGGATTAGAATGCCTGCCCCAAGGGGCCAGGCG
ACTGACGGTAGTCCTCACTGTGCTCACCAACGCCAGTTGGTAAGCACGGCAGCGGCAGCCTGCT
GTGTGACGTGGCCACCGCGTGCCCCCAGCCCGCACACTGTGCCCCTGCCTCCTGAACCTTGTGT
GCAGAATAAAGAGGGCGTTGAGTAACACT

hide sequence

RefSeq Acc Id:

XM_013362623 ⟹ XP_013218077

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	31,937,577 - 31,951,577 (+)	NCBI
SpeTri2.0	NW_004936623	2,422,832 - 2,436,817 (+)	NCBI

Sequence:

show sequence

CGCGTGCGTGCTGGGGTGAGCAGCCTTCGCTCCGCGGGGTGAGTGGGCCAGGCGTCGCGGAGCT
GCCGACCGCGTCGAGGCCTTCCACGGTGTTAAAACAACATCAAAATGGCTTCAAAAAGAGCCCT
GGTCATCCTGGCCAAAGGAGCAGAGGAGATGGAGACCGTTATCCCTGTGGATGTCATGAGAAGA
GCTGGGATTAAGGTCACGGTTGCAGGTCTGTCTGGAAAAGACCCAGTACAGTGTAGCCGTGATG
TTGTCATTTGTCCTGATGCCAGTCTTGAAGATGCACGAAAGCAGGGACCATACGATGTGGTGGT
TCTGCCAGGAGGTAATCTGGGTGCACAGAATTTATCTGAGTCTGCTGCTGTGAAGGAGATCCTG
AAGGAGCAGGAGAGCAGGAAGGGCCTCATAGCCGCCATCTGTGCAGGTCCTACGGCTCTTTTGG
CTCATGAAATAGGTTTTGGAAGTAAAGTTACAACACACCCACTTGCTAAAGACAAAATGATGAA
TGGGAGTCACTACAGCTATTCAGAGAGCCGCGTGGAACAGGACGGCCTGATCCTCACCAGCCGT
GGGCCTGGGACCAGCTTTGAGTTCGCCCTTGCCATCGTGGACGCGCTCATGGGCAAGGAGGTGG
CCAACCAGGTGAAGGCGCCCCTGGTTCTTAAGGATTAGAATGCCTGCCCCAAGGGGCCAGGCGA
CTGACGGTAGTCCTCACTGTGCTCACCAACGCCAGTTGGTAAGCACGGCAGCGGCAGCCTGCTG
TGTGACGTGGCCACCGCGTGCCCCCAGCCCGCACACTGTGCCCCTGCCTCCTGAACCTTGTGTG
CAGAATAAAGAGGGCGTTGAGTAACACT

hide sequence

RefSeq Acc Id:

XM_040287875 ⟹ XP_040143809

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	31,937,740 - 31,951,577 (+)	NCBI

RefSeq Acc Id:

XM_040287876 ⟹ XP_040143810

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	31,937,920 - 31,951,577 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005334797	(Get FASTA)	NCBI Sequence Viewer
	XP_013218077	(Get FASTA)	NCBI Sequence Viewer
	XP_040143809	(Get FASTA)	NCBI Sequence Viewer
	XP_040143810	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000022415.1
GenBank Protein	KAG3282049	(Get FASTA)	NCBI Sequence Viewer
	KAG3282050	(Get FASTA)	NCBI Sequence Viewer
	KAG3282051	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005334797 ⟸ XM_005334740
- UniProtKB:	I3NDG8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLSGKDPVQCSRDVVICPDASLEDARKQ GPYDVVVLPGGNLGAQNLSESAAVKEILKEQESRKGLIAAICAGPTALLAHEIGFGSKVTTHPL AKDKMMNGSHYSYSESRVEQDGLILTSRGPGTSFEFALAIVDALMGKEVANQVKAPLVLKD hide sequence

RefSeq Acc Id:	XP_013218077 ⟸ XM_013362623
- UniProtKB:	I3NDG8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLSGKDPVQCSRDVVICPDASLEDARKQ GPYDVVVLPGGNLGAQNLSESAAVKEILKEQESRKGLIAAICAGPTALLAHEIGFGSKVTTHPL AKDKMMNGSHYSYSESRVEQDGLILTSRGPGTSFEFALAIVDALMGKEVANQVKAPLVLKD hide sequence

RefSeq Acc Id:	XP_040143809 ⟸ XM_040287875
- UniProtKB:	I3NDG8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040143810 ⟸ XM_040287876
- UniProtKB:	I3NDG8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSSTOP00000022415 ⟸ ENSSTOT00000022865

Protein Domains

DJ-1/PfpI

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000025041	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000022865.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.880	UniProtKB/TrEMBL
InterPro	Class_I_gatase-like	UniProtKB/TrEMBL
	DJ-1	UniProtKB/TrEMBL
	DJ-1/PfpI	UniProtKB/TrEMBL
	Prot/Nucl_acid_deglycase	UniProtKB/TrEMBL
NCBI Gene	Park7	ENTREZGENE
PANTHER	PARKINSON DISEASE PROTEIN 7 HOMOLOG	UniProtKB/TrEMBL
	PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED	UniProtKB/TrEMBL
Pfam	DJ-1_PfpI	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52317	UniProtKB/TrEMBL
UniProt	I3NDG8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations