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Gene: HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1) Homo sapiens
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Symbol: HLA-DQA1
Name: major histocompatibility complex, class II, DQ alpha 1
Description: Predicted to have peptide antigen binding activity. Predicted to be involved in T cell receptor signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class II; and interferon-gamma-mediated signaling pathway. Localizes to membrane. Implicated in several diseases, including autoimmune hypersensitivity disease (multiple); bone inflammation disease (multiple); glucose metabolism disease (multiple); hematologic cancer (multiple); and liver disease (multiple). Biomarker of hepatitis C and juvenile rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD; CELIAC1; DC-1 alpha chain; DC-alpha; DQ-A1; DQA1; FLJ27088; FLJ27328; GSE; HLA class II histocompatibility antigen, DQ alpha 1 chain; HLA class II histocompatibility antigen, DQ(W3) alpha chain; HLA-DCA; HLA-DQA; leucocyte antigen DQA1; leukocyte antigen alpha chain; MGC149527; MHC class II antigen; MHC class II antigen DQA1; MHC class II DQ alpha chain; MHC class II DQA1; MHC class II HLA-D alpha glycoprotein; MHC class II HLA-DQ-alpha-1; MHC class II surface glycoprotein; MHC HLA-DQ alpha; truncated MHC class II antigen
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl632,628,179 - 32,647,062 (+)EnsemblGRCh38hg38GRCh38
GRCh38632,637,406 - 32,654,846 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37632,605,169 - 32,612,152 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,713,161 - 32,719,407 (+)NCBINCBI36hg18NCBI36
Build 34632,713,160 - 32,719,407NCBI
Cytogenetic Map6p21.32NCBI
HuRef632,346,937 - 32,353,106 (+)NCBIHuRef
CHM1_1632,607,658 - 32,613,904 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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