TLR3 (toll like receptor 3) - Rat Genome Database

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Gene: TLR3 (toll like receptor 3) Homo sapiens
Analyze
Symbol: TLR3
Name: toll like receptor 3
RGD ID: 1343581
HGNC Page HGNC:11849
Description: Enables double-stranded RNA binding activity; identical protein binding activity; and pattern recognition receptor activity. Involved in several processes, including pattern recognition receptor signaling pathway; positive regulation of cytokine production; and positive regulation of intracellular signal transduction. Acts upstream of or within response to exogenous dsRNA. Located in cytoplasm. Is active in early endosome. Implicated in several diseases, including hepatitis B; hepatitis C; human immunodeficiency virus infectious disease; liver cirrhosis; and primary immunodeficiency disease (multiple). Biomarker of several diseases, including Human papillomavirus infectious disease; Kuhnt-Junius degeneration; anogenital venereal wart; autoimmune disease (multiple); and gastrointestinal system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CD283; IIAE2; IMD83; toll-like receptor 3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in immune response or antiviral activity.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384186,069,156 - 186,088,073 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4186,068,911 - 186,088,073 (+)EnsemblGRCh38hg38GRCh38
GRCh374186,990,310 - 187,009,227 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364187,227,303 - 187,243,246 (+)NCBINCBI36Build 36hg18NCBI36
Build 344187,365,457 - 187,381,399NCBI
Celera4184,312,848 - 184,328,791 (+)NCBICelera
Cytogenetic Map4q35.1NCBI
HuRef4182,742,451 - 182,758,393 (+)NCBIHuRef
CHM1_14186,966,756 - 186,982,686 (+)NCBICHM1_1
T2T-CHM13v2.04189,409,568 - 189,428,483 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
1,2-dimethylhydrazine  (ISO)
1-Aminopyrene  (EXP)
1-nitropyrene  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-fluorouracil  (EXP)
acetamide  (ISO)
acetylsalicylic acid  (EXP)
actinomycin D  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (EXP)
aripiprazole  (EXP)
arsenous acid  (EXP)
benzene  (EXP)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisdemethoxycurcumin  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium dichloride  (ISO)
cadmium selenide  (EXP)
calcitriol  (EXP)
carbon nanotube  (EXP,ISO)
chenodeoxycholic acid  (EXP)
chlorogenic acid  (ISO)
chloroquine  (EXP)
chromium(6+)  (EXP)
cisplatin  (EXP,ISO)
cyanidin cation  (ISO)
cyclosporin A  (EXP)
deoxycholic acid  (EXP)
deoxynivalenol  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (EXP)
Dibutyl phosphate  (EXP)
dioxygen  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
folic acid  (EXP)
gentamycin  (ISO)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
GW 4064  (ISO)
hydroquinone  (EXP)
indole-3-methanol  (ISO)
indometacin  (EXP)
lidocaine  (ISO)
lipopolysaccharide  (EXP,ISO)
metam  (ISO)
metformin  (EXP)
methamphetamine  (ISO)
methotrexate  (EXP,ISO)
methoxychlor  (ISO)
nickel sulfate  (EXP)
nitrates  (ISO)
Nutlin-3  (EXP)
o-anisidine  (EXP)
ozone  (EXP)
paclitaxel  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentachlorophenol  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (EXP)
pirinixic acid  (ISO)
poly(I:C)  (EXP,ISO)
potassium chromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
pristane  (ISO)
pyrene  (EXP)
quinacrine  (EXP)
resveratrol  (ISO)
ruxolitinib  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 431542  (EXP)
serpentine asbestos  (EXP)
silicon dioxide  (EXP)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
sodium arsenite  (EXP)
sodium aurothiosulfate  (EXP)
sotorasib  (EXP)
streptozocin  (EXP,ISO)
Sunset Yellow FCF  (EXP)
tartrazine  (EXP)
testosterone  (EXP)
testosterone enanthate  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trametinib  (EXP)
triclosan  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
valproic acid  (EXP)
vinclozolin  (ISO)
zearalenone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of NF-kappaB-inducing kinase activity  (NAS)
cellular response to exogenous dsRNA  (IEA,ISO)
cellular response to interferon-beta  (IEA,ISO)
cellular response to mechanical stimulus  (IEP)
cellular response to type II interferon  (IEA,ISO)
cellular response to virus  (IEA)
cellular response to xenobiotic stimulus  (IEA,ISO)
defense response  (IEA,ISO)
defense response to bacterium  (TAS)
defense response to virus  (IEA,ISO,TAS)
detection of virus  (NAS)
extrinsic apoptotic signaling pathway  (IDA)
hyperosmotic response  (NAS)
I-kappaB phosphorylation  (IDA)
immune response  (IEA)
inflammatory response  (IEA)
inflammatory response to wounding  (IDA,IEA)
innate immune response  (IEA,TAS)
JNK cascade  (IEA,ISO)
male gonad development  (IEA,ISO)
MAPK cascade  (IEA)
microglial cell activation  (IEA,ISO)
necroptotic signaling pathway  (IDA)
negative regulation of osteoclast differentiation  (NAS)
positive regulation of angiogenesis  (IEA)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of canonical NF-kappaB signal transduction  (IEA,ISO)
positive regulation of chemokine production  (IDA,IEA,ISO)
positive regulation of cytokine production involved in inflammatory response  (IEA)
positive regulation of gene expression  (IMP)
positive regulation of inflammatory response  (IC)
positive regulation of interferon-alpha production  (IDA)
positive regulation of interferon-beta production  (IDA,IEA,IMP,ISS)
positive regulation of interleukin-12 production  (IEA,ISS)
positive regulation of interleukin-6 production  (IDA,IEA,ISO)
positive regulation of interleukin-8 production  (IDA)
positive regulation of JNK cascade  (IDA,IEA,ISO)
positive regulation of macrophage cytokine production  (IEA,ISO)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of non-canonical NF-kappaB signal transduction  (IDA)
positive regulation of transcription by RNA polymerase II  (IEA,ISS)
positive regulation of tumor necrosis factor production  (IEA,ISO,ISS)
positive regulation of type I interferon production  (IEA,ISO)
positive regulation of type II interferon production  (IDA)
positive regulation of type III interferon production  (IEA,ISO)
regulation of dendritic cell cytokine production  (IEA,ISO)
response to dsRNA  (IBA,IEA,ISO)
response to exogenous dsRNA  (IDA,IEA)
response to virus  (IEA,ISO)
signal transduction  (TAS)
toll-like receptor 3 signaling pathway  (IDA)
toll-like receptor signaling pathway  (IDA,IEA,ISO)
type III interferon production  (IEA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Toll-like receptor 3 gene expression in Egyptian patients with glomerulonephritis and hepatitis C virus infection. Abou-Zeid AA and El-Sayegh HK, Scand J Clin Lab Invest. 2011 Oct;71(6):456-61. doi: 10.3109/00365513.2011.585660. Epub 2011 May 30.
2. Toll-like receptor 3 polymorphism and its association with hepatitis B virus infection in Saudi Arabian patients. Al-Qahtani A, etal., J Med Virol. 2012 Sep;84(9):1353-9. doi: 10.1002/jmv.23271.
3. Activation of toll-like receptor 3 attenuates alcoholic liver injury by stimulating Kupffer cells and stellate cells to produce interleukin-10 in mice. Byun JS, etal., J Hepatol. 2013 Feb;58(2):342-9. doi: 10.1016/j.jhep.2012.09.016. Epub 2012 Sep 27.
4. Toll-like receptor 3 expressing tumor parenchyma and infiltrating natural killer cells in hepatocellular carcinoma patients. Chew V, etal., J Natl Cancer Inst. 2012 Dec 5;104(23):1796-807. doi: 10.1093/jnci/djs436. Epub 2012 Nov 29.
5. Rapidity of fibrosis progression in liver transplant recipients with recurrent hepatitis C is influenced by toll-like receptor 3 polymorphism. Citores MJ, etal., Clin Transplant. 2016 Jul;30(7):810-8. doi: 10.1111/ctr.12754. Epub 2016 May 23.
6. Association between toll-like receptor expression and human papillomavirus type 16 persistence. Daud II, etal., Int J Cancer. 2011 Feb 15;128(4):879-86. doi: 10.1002/ijc.25400.
7. The association of single nucleotide polymorphisms of Toll-like receptor 3, Toll-like receptor 7 and Toll-like receptor 8 genes with the susceptibility to HCV infection. El-Bendary M, etal., Br J Biomed Sci. 2018 Oct;75(4):175-181. doi: 10.1080/09674845.2018.1492186. Epub 2018 Aug 23.
8. Polymorphisms in the Toll-like receptor 3 (TLR3) gene are associated with the natural course of hepatitis B virus infection in Caucasian population. Fischer J, etal., Sci Rep. 2018 Aug 24;8(1):12737. doi: 10.1038/s41598-018-31065-6.
9. Up-regulation of Toll-like receptors 2, 3 and 4 in allergic rhinitis. Fransson M, etal., Respir Res. 2005 Sep 7;6:100.
10. Pre-activation of TLR3 enhances the therapeutic effect of BMMSCs through regulation the intestinal HIF-2α signaling pathway and balance of NKB cells in experimental alcoholic liver injury. Ge L, etal., Int Immunopharmacol. 2019 May;70:477-485. doi: 10.1016/j.intimp.2019.02.021. Epub 2019 Mar 12.
11. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
12. A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen. Greidinger EL, etal., Arthritis Rheum. 2006 Feb;54(2):661-9.
13. Combinations of TLR and NOD2 ligands stimulate rat microglial P2X4R expression. Guo LH, etal., Biochem Biophys Res Commun. 2006 Oct 27;349(3):1156-62. Epub 2006 Sep 1.
14. Association of Toll-like receptor 3 and Toll-like receptor 9 single-nucleotide polymorphisms with hepatitis C virus persistence among Egyptians. Hamdy S, etal., Arch Virol. 2018 Sep;163(9):2433-2442. doi: 10.1007/s00705-018-3893-8. Epub 2018 Jun 2.
15. Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis. Harii N, etal., Mol Endocrinol. 2005 May;19(5):1231-50. Epub 2005 Jan 20.
16. A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. Hayashida K and Eisenach JC, J Pain. 2011 Jan;12(1):94-100.
17. Epithelial Cells From Smokers Modify Dendritic Cell Responses in the Context of Influenza Infection. Horvath KM, etal., Am J Respir Cell Mol Biol. 2010 Oct 8.
18. Genetic polymorphisms in Toll-like receptor 3 gene are associated with the risk of hepatitis B virus-related liver diseases in a Chinese population. Huang X, etal., Gene. 2015 Sep 15;569(2):218-24. doi: 10.1016/j.gene.2015.05.054. Epub 2015 May 27.
19. TLR3 increases disease morbidity and mortality from vaccinia infection. Hutchens M, etal., J Immunol. 2008 Jan 1;180(1):483-91.
20. TH2 and TH1 lung inflammation induced by airway allergen sensitization with low and high doses of double-stranded RNA. Jeon SG, etal., J Allergy Clin Immunol. 2007 Oct;120(4):803-12. Epub 2007 Jul 5.
21. TLR3 modulates immunopathology during a Schistosoma mansoni egg-driven Th2 response in the lung. Joshi AD, etal., Eur J Immunol. 2008 Dec;38(12):3436-49.
22. Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway. Kang JW, etal., J Pineal Res. 2011 Feb 28. doi: 10.1111/j.1600-079X.2011.00858.x.
23. Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. Kang MJ, etal., J Clin Invest. 2008 Aug;118(8):2771-84.
24. Down regulation of TRIF, TLR3, and MAVS in HCV infected liver correlates with the outcome of infection. Kar P, etal., J Med Virol. 2017 Dec;89(12):2165-2172. doi: 10.1002/jmv.24849. Epub 2017 Sep 4.
25. Pathogen recognition by the innate immune system. Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34.
26. Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia. Le Goffic R, etal., PLoS Pathog. 2006 Jun;2(6):e53. Epub 2006 Jun 9.
27. Association between a functional polymorphism in Toll-like receptor 3 and chronic hepatitis C in liver transplant recipients. Lee SO, etal., Transpl Infect Dis. 2013 Apr;15(2):111-9. doi: 10.1111/tid.12033. Epub 2012 Dec 13.
28. Higher expression of Toll-like receptors 2, 3, 4, and 8 in ocular Behcet's disease. Liu X, etal., Invest Ophthalmol Vis Sci. 2013 Sep 5;54(9):6012-7. doi: 10.1167/iovs.13-12159.
29. Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis. Liu Y, etal., Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G442-50. Epub 2009 Jul 16.
30. TLR3 in human eosinophils: functional effects and decreased expression during allergic rhinitis. Mansson A, etal., Int Arch Allergy Immunol. 2010;151(2):118-28. Epub 2009 Sep 15.
31. Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome. McKernan DP, etal., PLoS One. 2009 Dec 9;4(12):e8226.
32. Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats. Meng L, etal., Arthritis Res Ther. 2010;12(3):R103. Epub 2010 May 25.
33. TLR3 and TLR7 Modulate IgE Production in Antigen Induced Pulmonary Inflammation via Influencing IL-4 Expression in Immune Organs. Meng L, etal., PLoS One. 2011 Feb 25;6(2):e17252.
34. Association between Toll-Like Receptor 3 (TLR3) rs3775290, TLR7 rs179008, TLR9 rs352140 and Chronic HCV. Mosaad YM, etal., Immunol Invest. 2019 Apr;48(3):321-332. doi: 10.1080/08820139.2018.1527851. Epub 2018 Oct 15.
35. Deleterious role of TLR3 during hyperoxia-induced acute lung injury. Murray LA, etal., Am J Respir Crit Care Med. 2008 Dec 15;178(12):1227-37. Epub 2008 Oct 10.
36. An association study of asthma and total serum immunoglobin E levels for Toll-like receptor polymorphisms in a Japanese population. Noguchi E, etal., Clin Exp Allergy. 2004 Feb;34(2):177-83.
37. The expression and function of Toll-like receptors 3 and 9 in human colon carcinoma. Nojiri K, etal., Oncol Rep. 2013 May;29(5):1737-43. doi: 10.3892/or.2013.2322. Epub 2013 Mar 4.
38. The bacteriostatic protein lipocalin 2 is induced in the central nervous system of mice with west Nile virus encephalitis. Noçon AL, etal., J Virol. 2014 Jan;88(1):679-89. doi: 10.1128/JVI.02094-13. Epub 2013 Oct 30.
39. Toll-like receptor 3 contributes to spinal glial activation and tactile allodynia after nerve injury. Obata K, etal., J Neurochem. 2008 Jun 1;105(6):2249-59.
40. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
41. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
42. Toll-like receptor 3 gene polymorphisms in South African Blacks with type 1 diabetes. Pirie FJ, etal., Tissue Antigens. 2005 Aug;66(2):125-30.
43. Impaired toll-like receptor 3-mediated immune responses from macrophages of patients chronically infected with hepatitis C virus. Qian F, etal., Clin Vaccine Immunol. 2013 Feb;20(2):146-55. doi: 10.1128/CVI.00530-12. Epub 2012 Dec 5.
44. Spinal toll like receptor 3 is involved in chronic pancreatitis-induced mechanical allodynia of rat. Qian NS, etal., Mol Pain. 2011 Feb 22;7(1):15.
45. Effects of single nucleotide polymorphisms on Toll-like receptor 3 activity and expression in cultured cells. Ranjith-Kumar CT, etal., J Biol Chem. 2007 Jun 15;282(24):17696-705. Epub 2007 Apr 13.
46. Toll-like receptor expression and activation in mice with experimental dry eye. Redfern RL, etal., Invest Ophthalmol Vis Sci. 2013 Feb 28;54(2):1554-63. doi: 10.1167/iovs.12-10739.
47. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
48. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
49. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
50. Expression of toll-like receptors 2, 4 and 9 is increased in gingival tissue from patients with type 2 diabetes and chronic periodontitis. Rojo-Botello NR, etal., J Periodontal Res. 2012 Feb;47(1):62-73. doi: 10.1111/j.1600-0765.2011.01405.x. Epub 2011 Aug 17.
51. Association of Toll-like receptor 3 polymorphisms with chronic hepatitis B and hepatitis B-related acute-on-chronic liver failure. Rong Y, etal., Inflammation. 2013 Apr;36(2):413-8. doi: 10.1007/s10753-012-9560-4.
52. Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection. Rudd BD, etal., J Immunol. 2006 Feb 1;176(3):1937-42.
53. Exosome-mediated activation of toll-like receptor 3 in stellate cells stimulates interleukin-17 production by γδ T cells in liver fibrosis. Seo W, etal., Hepatology. 2016 Aug;64(2):616-31. doi: 10.1002/hep.28644. Epub 2016 Jun 29.
54. Mechanistic investigation of immunosuppression in patients with condyloma acuminata. Shi YJ, etal., Mol Med Rep. 2013 Aug;8(2):480-6. doi: 10.3892/mmr.2013.1511. Epub 2013 Jun 6.
55. Toll-like receptor 3 activation during pregnancy elicits preeclampsia-like symptoms in rats. Tinsley JH, etal., Am J Hypertens. 2009 Dec;22(12):1314-9. Epub 2009 Sep 24.
56. Characterization of innate immune signalling receptors in virus-induced acute asthma. Wood LG, etal., Clin Exp Allergy. 2010 Dec 3. doi: 10.1111/j.1365-2222.2010.03669.x.
57. Hepatic Toll-Like Receptor 3 expression in chronic hepatitis C genotype 1 correlates with treatment response to peginterferon plus ribavirin. Yuki N, etal., J Viral Hepat. 2010 Feb 1;17(2):130-8. doi: 10.1111/j.1365-2893.2009.01155.x. Epub 2009 Aug 5.
58. Increase in peripheral blood mononuclear cell Toll-like receptor 2/3 expression and reactivity to their ligands in a cohort of patients with wet age-related macular degeneration. Zhu Y, etal., Mol Vis. 2013 Aug 6;19:1826-33. eCollection 2013.
Additional References at PubMed
PMID:9435236   PMID:10066798   PMID:10426995   PMID:10820283   PMID:11561001   PMID:11607032   PMID:11782555   PMID:12054664   PMID:12133979   PMID:12477932   PMID:12509442   PMID:12539043  
PMID:12609980   PMID:12646618   PMID:12672806   PMID:12692549   PMID:12855817   PMID:14519765   PMID:14557267   PMID:14575692   PMID:14729660   PMID:14982987   PMID:15064760   PMID:15107846  
PMID:15119015   PMID:15153468   PMID:15212709   PMID:15226270   PMID:15315972   PMID:15340161   PMID:15356140   PMID:15502848   PMID:15579900   PMID:15652398   PMID:15731229   PMID:15737993  
PMID:15767394   PMID:15778392   PMID:15845391   PMID:15935884   PMID:15961631   PMID:15972671   PMID:16035096   PMID:16043704   PMID:16111635   PMID:16115877   PMID:16144834   PMID:16160153  
PMID:16286015   PMID:16289658   PMID:16293707   PMID:16344560   PMID:16399790   PMID:16424203   PMID:16473828   PMID:16482523   PMID:16484229   PMID:16533755   PMID:16585585   PMID:16628196  
PMID:16720699   PMID:16847112   PMID:16858407   PMID:16877304   PMID:16914605   PMID:16935934   PMID:16950283   PMID:17043099   PMID:17085778   PMID:17128265   PMID:17142768   PMID:17142772  
PMID:17150911   PMID:17178723   PMID:17209042   PMID:17254392   PMID:17292969   PMID:17301562   PMID:17314152   PMID:17449641   PMID:17521732   PMID:17525119   PMID:17534115   PMID:17573354  
PMID:17602875   PMID:17626075   PMID:17660379   PMID:17703412   PMID:17786279   PMID:17805015   PMID:17851256   PMID:17872438   PMID:17878161   PMID:17897319   PMID:17908959   PMID:17939877  
PMID:17947455   PMID:17962643   PMID:17962701   PMID:17963596   PMID:17964520   PMID:17982077   PMID:18021446   PMID:18029758   PMID:18172197   PMID:18204787   PMID:18253710   PMID:18262679  
PMID:18325643   PMID:18367536   PMID:18385087   PMID:18394314   PMID:18437017   PMID:18442983   PMID:18508883   PMID:18541719   PMID:18544529   PMID:18562533   PMID:18566014   PMID:18566393  
PMID:18568036   PMID:18684960   PMID:18686608   PMID:18715647   PMID:18725521   PMID:18753640   PMID:18775079   PMID:18776324   PMID:18776592   PMID:18779317   PMID:18810425   PMID:18813073  
PMID:18818748   PMID:18832709   PMID:18946062   PMID:18949355   PMID:18978302   PMID:18988918   PMID:19001446   PMID:19016379   PMID:19019335   PMID:19035519   PMID:19055649   PMID:19120481  
PMID:19134117   PMID:19164128   PMID:19231996   PMID:19234180   PMID:19247444   PMID:19254290   PMID:19258923   PMID:19265130   PMID:19299748   PMID:19362356   PMID:19378782   PMID:19423540  
PMID:19437550   PMID:19475618   PMID:19494321   PMID:19505919   PMID:19522763   PMID:19527514   PMID:19542247   PMID:19593445   PMID:19597128   PMID:19625408   PMID:19628747   PMID:19631980  
PMID:19646728   PMID:19656899   PMID:19740627   PMID:19741468   PMID:19748983   PMID:19758322   PMID:19769802   PMID:19779021   PMID:19795416   PMID:19810822   PMID:19833099   PMID:19855253  
PMID:19878930   PMID:19887600   PMID:19890046   PMID:19902255   PMID:19914718   PMID:19948350   PMID:19951172   PMID:19966137   PMID:19966777   PMID:20009359   PMID:20047764   PMID:20100933  
PMID:20124101   PMID:20194452   PMID:20197609   PMID:20200155   PMID:20227302   PMID:20237496   PMID:20309865   PMID:20331378   PMID:20367642   PMID:20381870   PMID:20406303   PMID:20406964  
PMID:20422193   PMID:20438785   PMID:20452482   PMID:20472559   PMID:20483009   PMID:20483744   PMID:20483774   PMID:20503287   PMID:20514466   PMID:20523058   PMID:20588308   PMID:20595247  
PMID:20604744   PMID:20636339   PMID:20639488   PMID:20651983   PMID:20673868   PMID:20685081   PMID:20691286   PMID:20819670   PMID:20832341   PMID:20855885   PMID:20957750   PMID:20977567  
PMID:20978888   PMID:21061265   PMID:21079408   PMID:21093032   PMID:21129170   PMID:21132533   PMID:21148036   PMID:21173679   PMID:21179282   PMID:21189260   PMID:21216866   PMID:21220319  
PMID:21223583   PMID:21239167   PMID:21245912   PMID:21255094   PMID:21266579   PMID:21367858   PMID:21398612   PMID:21454254   PMID:21474651   PMID:21481769   PMID:21498625   PMID:21515789  
PMID:21563279   PMID:21646299   PMID:21691053   PMID:21695056   PMID:21708001   PMID:21712495   PMID:21722947   PMID:21730023   PMID:21735101   PMID:21737330   PMID:21802664   PMID:21829730  
PMID:21839239   PMID:21843566   PMID:21844166   PMID:21847628   PMID:21873635   PMID:21903422   PMID:21911421   PMID:21911422   PMID:21911501   PMID:21911973   PMID:21931545   PMID:21949112  
PMID:21952237   PMID:21960283   PMID:21978158   PMID:21990957   PMID:21998457   PMID:22016778   PMID:22024499   PMID:22030901   PMID:22038398   PMID:22039520   PMID:22057682   PMID:22065573  
PMID:22070917   PMID:22102050   PMID:22147891   PMID:22174453   PMID:22200507   PMID:22205631   PMID:22205660   PMID:22260507   PMID:22310660   PMID:22323545   PMID:22415225   PMID:22421267  
PMID:22421964   PMID:22429150   PMID:22457005   PMID:22466005   PMID:22479513   PMID:22504413   PMID:22537752   PMID:22549436   PMID:22552940   PMID:22568929   PMID:22572822   PMID:22579623  
PMID:22590509   PMID:22591330   PMID:22611194   PMID:22685032   PMID:22745793   PMID:22759966   PMID:22762377   PMID:22771581   PMID:22849850   PMID:22851595   PMID:22864531   PMID:22865861  
PMID:22912896   PMID:22944378   PMID:22948160   PMID:22950839   PMID:22960172   PMID:22989785   PMID:23053995   PMID:23056170   PMID:23056470   PMID:23103873   PMID:23115281   PMID:23151015  
PMID:23155421   PMID:23166319   PMID:23179584   PMID:23245579   PMID:23255072   PMID:23255358   PMID:23269203   PMID:23290562   PMID:23353987   PMID:23369718   PMID:23396947   PMID:23404408  
PMID:23425350   PMID:23489702   PMID:23497334   PMID:23534905   PMID:23541683   PMID:23548575   PMID:23647955   PMID:23668802   PMID:23673618   PMID:23716670   PMID:23717201   PMID:23721942  
PMID:23723066   PMID:23744559   PMID:23748743   PMID:23796347   PMID:23817958   PMID:23844087   PMID:23845419   PMID:23948864   PMID:23962581   PMID:23962979   PMID:24028589   PMID:24068346  
PMID:24070541   PMID:24084648   PMID:24105952   PMID:24131248   PMID:24146036   PMID:24155891   PMID:24165198   PMID:24198284   PMID:24286242   PMID:24321786   PMID:24371259   PMID:24408902  
PMID:24445780   PMID:24524192   PMID:24530528   PMID:24535857   PMID:24558379   PMID:24565447   PMID:24600555   PMID:24651439   PMID:24651829   PMID:24672048   PMID:24682730   PMID:24692849  
PMID:24693944   PMID:24701034   PMID:24708416   PMID:24709775   PMID:24712925   PMID:24719229   PMID:24739633   PMID:24760149   PMID:24766260   PMID:24768503   PMID:24786223   PMID:24791904  
PMID:24819172   PMID:24845156   PMID:24886842   PMID:24889229   PMID:24905199   PMID:24934575   PMID:25008898   PMID:25014275   PMID:25092290   PMID:25098814   PMID:25121361   PMID:25126563  
PMID:25127040   PMID:25171086   PMID:25171218   PMID:25204797   PMID:25214272   PMID:25217833   PMID:25226020   PMID:25257174   PMID:25304972   PMID:25309919   PMID:25339207   PMID:25348355  
PMID:25373689   PMID:25388852   PMID:25423559   PMID:25436985   PMID:25444175   PMID:25452586   PMID:25471749   PMID:25594115   PMID:25605704   PMID:25640309   PMID:25641411   PMID:25652132  
PMID:25668563   PMID:25689620   PMID:25695694   PMID:25720507   PMID:25736436   PMID:25754842   PMID:25754930   PMID:25780039   PMID:25794662   PMID:25867514   PMID:25880109   PMID:25891078  
PMID:25912131   PMID:25918231   PMID:25992926   PMID:26077030   PMID:26100173   PMID:26123900   PMID:26172457   PMID:26208481   PMID:26226228   PMID:26238371   PMID:26253200   PMID:26255864  
PMID:26296370   PMID:26298326   PMID:26303210   PMID:26313906   PMID:26318748   PMID:26318769   PMID:26367324   PMID:26417991   PMID:26418032   PMID:26466955   PMID:26512422   PMID:26536229  
PMID:26548749   PMID:26584291   PMID:26589477   PMID:26646717   PMID:26680366   PMID:26796995   PMID:26797279   PMID:26891958   PMID:26956584   PMID:26959380   PMID:26979086   PMID:26980049  
PMID:26980664   PMID:27031066   PMID:27059791   PMID:27121087   PMID:27129228   PMID:27162029   PMID:27183205   PMID:27191981   PMID:27227908   PMID:27270888   PMID:27277333   PMID:27314608  
PMID:27329385   PMID:27338037   PMID:27375111   PMID:27422384   PMID:27505671   PMID:27533082   PMID:27567430   PMID:27571579   PMID:27586271   PMID:27593154   PMID:27605546   PMID:27639618  
PMID:27649928   PMID:27682462   PMID:27729782   PMID:27791989   PMID:27793801   PMID:27805282   PMID:27810922   PMID:27830702   PMID:27940139   PMID:28009434   PMID:28017496   PMID:28046022  
PMID:28052863   PMID:28093541   PMID:28100320   PMID:28100913   PMID:28109979   PMID:28127569   PMID:28166799   PMID:28190199   PMID:28210837   PMID:28266028   PMID:28302793   PMID:28359509  
PMID:28368532   PMID:28479387   PMID:28510725   PMID:28544067   PMID:28621230   PMID:28626766   PMID:28659487   PMID:28703296   PMID:28717003   PMID:28823914   PMID:28844021   PMID:29070776  
PMID:29128906   PMID:29166644   PMID:29214775   PMID:29237089   PMID:29264743   PMID:29273868   PMID:29290528   PMID:29305044   PMID:29368829   PMID:29395019   PMID:29505789   PMID:29507755  
PMID:29528590   PMID:29535029   PMID:29567028   PMID:29616030   PMID:29676528   PMID:29679565   PMID:29698627   PMID:29702280   PMID:29742501   PMID:29791907   PMID:29845280   PMID:29959987  
PMID:29975469   PMID:30076830   PMID:30154162   PMID:30158588   PMID:30211629   PMID:30378322   PMID:30409294   PMID:30421643   PMID:30476912   PMID:30481825   PMID:30506923   PMID:30563052  
PMID:30614571   PMID:30649440   PMID:30659926   PMID:30664289   PMID:30735502   PMID:30758987   PMID:30808838   PMID:30842554   PMID:30944148   PMID:30954023   PMID:31021550   PMID:31024557  
PMID:31076723   PMID:31111539   PMID:31129058   PMID:31138474   PMID:31177052   PMID:31217193   PMID:31268141   PMID:31330219   PMID:31333667   PMID:31336144   PMID:31352487   PMID:31456484  
PMID:31481269   PMID:31511519   PMID:31570448   PMID:31582772   PMID:31604943   PMID:31686029   PMID:31776046   PMID:31801911   PMID:31838086   PMID:31896590   PMID:31902237   PMID:31969218  
PMID:32093313   PMID:32124747   PMID:32189594   PMID:32335220   PMID:32354189   PMID:32363951   PMID:32461989   PMID:32529819   PMID:32555540   PMID:32578708   PMID:32634389   PMID:32696505  
PMID:32715615   PMID:32770578   PMID:32888783   PMID:32912361   PMID:32936395   PMID:32939755   PMID:32988857   PMID:32999457   PMID:33036630   PMID:33138336   PMID:33144569   PMID:33148381  
PMID:33148838   PMID:33174085   PMID:33215406   PMID:33387195   PMID:33393505   PMID:33432245   PMID:33535235   PMID:33594613   PMID:33616867   PMID:33650302   PMID:33892179   PMID:33913550  
PMID:33961781   PMID:33965533   PMID:34001091   PMID:34011952   PMID:34061379   PMID:34207750   PMID:34223897   PMID:34315957   PMID:34342515   PMID:34369985   PMID:34657879   PMID:34726731  
PMID:34826050   PMID:34906906   PMID:34964709   PMID:34985402   PMID:35000541   PMID:35063671   PMID:35156780   PMID:35196173   PMID:35277480   PMID:35343654   PMID:35392757   PMID:35459743  
PMID:35579180   PMID:35584177   PMID:35750257   PMID:35758265   PMID:35790769   PMID:35801751   PMID:35855659   PMID:35912640   PMID:35967300   PMID:36048530   PMID:36112878   PMID:36271773  
PMID:36310878   PMID:36422693   PMID:36478230   PMID:36503883   PMID:36631495   PMID:37013819   PMID:37020259   PMID:37040285   PMID:37060811   PMID:37158982   PMID:37510216   PMID:37526179  
PMID:37894949   PMID:37933090   PMID:38019252   PMID:38031182   PMID:38049523   PMID:38062829   PMID:38102721   PMID:38173795   PMID:38316991   PMID:38551071   PMID:38864429   PMID:38868969  
PMID:38907187   PMID:39259342  


Genomics

Comparative Map Data
TLR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384186,069,156 - 186,088,073 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4186,068,911 - 186,088,073 (+)EnsemblGRCh38hg38GRCh38
GRCh374186,990,310 - 187,009,227 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364187,227,303 - 187,243,246 (+)NCBINCBI36Build 36hg18NCBI36
Build 344187,365,457 - 187,381,399NCBI
Celera4184,312,848 - 184,328,791 (+)NCBICelera
Cytogenetic Map4q35.1NCBI
HuRef4182,742,451 - 182,758,393 (+)NCBIHuRef
CHM1_14186,966,756 - 186,982,686 (+)NCBICHM1_1
T2T-CHM13v2.04189,409,568 - 189,428,483 (+)NCBIT2T-CHM13v2.0
Tlr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39845,848,702 - 45,864,112 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl845,848,702 - 45,864,117 (-)EnsemblGRCm39 Ensembl
GRCm38845,395,665 - 45,411,075 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl845,395,665 - 45,411,080 (-)EnsemblGRCm38mm10GRCm38
MGSCv37846,481,019 - 46,495,893 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36846,894,482 - 46,909,356 (-)NCBIMGSCv36mm8
Celera848,083,156 - 48,098,074 (-)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map825.31NCBI
Tlr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81653,554,916 - 53,572,321 (+)NCBIGRCr8
mRatBN7.21646,821,980 - 46,837,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1646,822,039 - 46,836,545 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1652,215,759 - 52,229,258 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01655,592,446 - 55,605,923 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01650,855,155 - 50,868,654 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01650,016,466 - 50,031,011 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1650,016,857 - 50,031,214 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01649,739,814 - 49,753,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41650,112,910 - 50,126,371 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11650,112,984 - 50,126,440 (+)NCBI
Celera1644,813,138 - 44,826,566 (+)NCBICelera
Cytogenetic Map16q11NCBI
Tlr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540322,979,120 - 23,001,467 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540322,977,882 - 23,001,392 (-)NCBIChiLan1.0ChiLan1.0
TLR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23183,809,517 - 183,827,550 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14184,159,046 - 184,176,924 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04178,238,352 - 178,256,264 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14190,446,487 - 190,462,728 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4190,446,487 - 190,462,728 (+)Ensemblpanpan1.1panPan2
TLR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11644,617,012 - 44,633,591 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1644,550,846 - 44,653,247 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1645,103,720 - 45,132,454 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01646,830,974 - 46,859,705 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1646,831,107 - 46,846,486 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11644,798,956 - 44,827,679 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01645,411,963 - 45,440,690 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01645,543,452 - 45,571,950 (-)NCBIUU_Cfam_GSD_1.0
Tlr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494334,721,792 - 34,740,517 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365543,369,469 - 3,385,907 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365543,370,766 - 3,388,125 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1546,969,006 - 46,979,291 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11546,966,262 - 46,977,774 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21553,839,254 - 53,852,671 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TLR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17131,991,068 - 132,014,366 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7131,991,029 - 132,016,232 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037112,309,987 - 112,333,459 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tlr3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476916,925,984 - 16,941,196 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476916,925,969 - 16,945,250 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TLR3
410 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_003265.3(TLR3):c.34G>C (p.Gly12Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000524712] Chr4:186076653 [GRCh38]
Chr4:186997807 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2209T>A (p.Ser737Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000528448] Chr4:186083895 [GRCh38]
Chr4:187005049 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.2385G>A (p.Ala795=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001494010] Chr4:186084071 [GRCh38]
Chr4:187005225 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1927C>A (p.Arg643Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000547764] Chr4:186083613 [GRCh38]
Chr4:187004767 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.1704C>T (p.Asn568=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000528537] Chr4:186083390 [GRCh38]
Chr4:187004544 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.1660C>T (p.Pro554Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647016]|Immunodeficiency 83, susceptibility to viral infections [RCV000007044]|Susceptibility to HIV infection [RCV002496289]|not specified [RCV000826059] Chr4:186083346 [GRCh38]
Chr4:187004500 [GRCh37]
Chr4:4q35.1		 risk factor|uncertain significance
GRCh38/hg38 4q34.3-35.1(chr4:181579626-186100199)x1 copy number loss See cases [RCV000050324] Chr4:181579626..186100199 [GRCh38]
Chr4:182500779..187021353 [GRCh37]
Chr4:182737773..187258347 [NCBI36]
Chr4:4q34.3-35.1		 pathogenic
NM_003265.3(TLR3):c.1234C>T (p.Leu412Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001519768]|Immunodeficiency 83, susceptibility to viral infections [RCV000610503]|Susceptibility to HIV infection [RCV000034357]|Susceptibility to HIV infection [RCV002490456]|TLR3-related disorder [RCV003974868]|not provided [RCV001642535]|not specified [RCV000455666] Chr4:186082920 [GRCh38]
Chr4:187004074 [GRCh37]
Chr4:4q35.1		 pathogenic|benign|likely benign|conflicting interpretations of pathogenicity|protective
GRCh38/hg38 4q34.1-35.2(chr4:173599911-188624331)x1 copy number loss See cases [RCV000050771] Chr4:173599911..188624331 [GRCh38]
Chr4:174521062..189545485 [GRCh37]
Chr4:174757637..189782479 [NCBI36]
Chr4:4q34.1-35.2		 pathogenic
GRCh38/hg38 4q32.2-35.2(chr4:162013220-189975519)x3 copy number gain See cases [RCV000050649] Chr4:162013220..189975519 [GRCh38]
Chr4:162934372..190828225 [GRCh37]
Chr4:163153822..191133668 [NCBI36]
Chr4:4q32.2-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:183528264-188624331)x1 copy number loss See cases [RCV000050665] Chr4:183528264..188624331 [GRCh38]
Chr4:184449417..189545485 [GRCh37]
Chr4:184686411..189782479 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q34.2-35.2(chr4:175483683-189975519)x1 copy number loss See cases [RCV000051215] Chr4:175483683..189975519 [GRCh38]
Chr4:176404834..190828225 [GRCh37]
Chr4:176641828..191133668 [NCBI36]
Chr4:4q34.2-35.2		 pathogenic
GRCh38/hg38 4q26-35.2(chr4:118065569-190042639)x3 copy number gain See cases [RCV000051785] Chr4:118065569..190042639 [GRCh38]
Chr4:118986724..190828225 [GRCh37]
Chr4:119206172..191200788 [NCBI36]
Chr4:4q26-35.2		 pathogenic
GRCh38/hg38 4q27-35.2(chr4:121518223-190062270)x3 copy number gain See cases [RCV000051786] Chr4:121518223..190062270 [GRCh38]
Chr4:122439378..190828225 [GRCh37]
Chr4:122658828..191220419 [NCBI36]
Chr4:4q27-35.2		 pathogenic
GRCh38/hg38 4q31.23-35.2(chr4:148356485-189548183)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051789]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051789]|See cases [RCV000051789] Chr4:148356485..189548183 [GRCh38]
Chr4:149277637..190469337 [GRCh37]
Chr4:149497087..190706331 [NCBI36]
Chr4:4q31.23-35.2		 pathogenic
GRCh38/hg38 4q32.3-35.2(chr4:167218288-189975519)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051792]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051792]|See cases [RCV000051792] Chr4:167218288..189975519 [GRCh38]
Chr4:168139439..190828225 [GRCh37]
Chr4:168376014..191133668 [NCBI36]
Chr4:4q32.3-35.2		 pathogenic
GRCh38/hg38 4q34.1-35.2(chr4:172200228-189975519)x3 copy number gain See cases [RCV000051804] Chr4:172200228..189975519 [GRCh38]
Chr4:173121379..190828225 [GRCh37]
Chr4:173357954..191133668 [NCBI36]
Chr4:4q34.1-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:179946068-189548183)x3 copy number gain See cases [RCV000051805] Chr4:179946068..189548183 [GRCh38]
Chr4:180867221..190469337 [GRCh37]
Chr4:181104215..190706331 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185738786-186557156)x3 copy number gain See cases [RCV000051657] Chr4:185738786..186557156 [GRCh38]
Chr4:186659940..187478310 [GRCh37]
Chr4:186896934..187715304 [NCBI36]
Chr4:4q35.1-35.2		 uncertain significance
GRCh38/hg38 4q32.1-35.2(chr4:158568335-189975660)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053325]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053325]|See cases [RCV000053325] Chr4:158568335..189975660 [GRCh38]
Chr4:159489487..190828225 [GRCh37]
Chr4:159708937..191133809 [NCBI36]
Chr4:4q32.1-35.2		 pathogenic
GRCh38/hg38 4q32.3-35.2(chr4:163651681-189975519)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053327]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053327]|See cases [RCV000053327] Chr4:163651681..189975519 [GRCh38]
Chr4:164572833..190828225 [GRCh37]
Chr4:164792283..191133668 [NCBI36]
Chr4:4q32.3-35.2		 pathogenic
GRCh38/hg38 4q32.3-35.2(chr4:164039530-189982708)x1 copy number loss See cases [RCV000053347] Chr4:164039530..189982708 [GRCh38]
Chr4:164960682..190828225 [GRCh37]
Chr4:165180132..191140857 [NCBI36]
Chr4:4q32.3-35.2		 pathogenic
GRCh38/hg38 4q34.1-35.2(chr4:171507704-189869726)x1 copy number loss See cases [RCV000053349] Chr4:171507704..189869726 [GRCh38]
Chr4:172428855..190790881 [GRCh37]
Chr4:172665430..191027875 [NCBI36]
Chr4:4q34.1-35.2		 pathogenic
GRCh38/hg38 4q34.1-35.2(chr4:172356988-189975519)x1 copy number loss See cases [RCV000053352] Chr4:172356988..189975519 [GRCh38]
Chr4:173278139..190828225 [GRCh37]
Chr4:173514714..191133668 [NCBI36]
Chr4:4q34.1-35.2		 pathogenic
GRCh38/hg38 4q34.1-35.2(chr4:173754675-189343295)x1 copy number loss See cases [RCV000053353] Chr4:173754675..189343295 [GRCh38]
Chr4:174675826..190264449 [GRCh37]
Chr4:174912401..190501443 [NCBI36]
Chr4:4q34.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:183354112-190042639)x1 copy number loss See cases [RCV000053378] Chr4:183354112..190042639 [GRCh38]
Chr4:184275265..190828225 [GRCh37]
Chr4:184512259..191200788 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185074103-189867552)x1 copy number loss See cases [RCV000053379] Chr4:185074103..189867552 [GRCh38]
Chr4:185995257..190788707 [GRCh37]
Chr4:186232251..191025701 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185351249-189867552)x1 copy number loss See cases [RCV000053394] Chr4:185351249..189867552 [GRCh38]
Chr4:186272403..190788707 [GRCh37]
Chr4:186509397..191025701 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185498280-186984787)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053395]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053395]|See cases [RCV000053395] Chr4:185498280..186984787 [GRCh38]
Chr4:186419434..187905941 [GRCh37]
Chr4:186656428..188142935 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q34.2-35.2(chr4:176263514-189975519)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053373]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053373]|See cases [RCV000053373] Chr4:176263514..189975519 [GRCh38]
Chr4:177184665..190828225 [GRCh37]
Chr4:177421659..191133668 [NCBI36]
Chr4:4q34.2-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:177442769-190042639)x1 copy number loss See cases [RCV000053374] Chr4:177442769..190042639 [GRCh38]
Chr4:178363923..190828225 [GRCh37]
Chr4:178600917..191200788 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:179669472-189975660)x1 copy number loss See cases [RCV000053375] Chr4:179669472..189975660 [GRCh38]
Chr4:180590625..190828225 [GRCh37]
Chr4:180827619..191133809 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:179945868-189975660)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053376]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053376]|See cases [RCV000053376] Chr4:179945868..189975660 [GRCh38]
Chr4:180867021..190828225 [GRCh37]
Chr4:181104015..191133809 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:181455566-189975660)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053377]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053377]|See cases [RCV000053377] Chr4:181455566..189975660 [GRCh38]
Chr4:182376719..190828225 [GRCh37]
Chr4:182613713..191133809 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
NM_003265.3(TLR3):c.138C>T (p.Pro46=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003087782] Chr4:186076757 [GRCh38]
Chr4:186997911 [GRCh37]
Chr4:187234905 [NCBI36]
Chr4:4q35.1		 likely benign|not provided
NM_003265.3(TLR3):c.1038T>A (p.Ile346=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001213666] Chr4:186082724 [GRCh38]
Chr4:187003878 [GRCh37]
Chr4:4q35.1		 likely benign|uncertain significance
GRCh38/hg38 4q35.1-35.2(chr4:184327081-189975519)x3 copy number gain See cases [RCV000133708] Chr4:184327081..189975519 [GRCh38]
Chr4:185248234..190828225 [GRCh37]
Chr4:185485228..191133668 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:184327081-189975519)x1 copy number loss See cases [RCV000133709] Chr4:184327081..189975519 [GRCh38]
Chr4:185248234..190896674 [GRCh37]
Chr4:185485228..191133668 [NCBI36]
Chr4:4q35.1-35.2		 likely pathogenic|likely benign
GRCh38/hg38 4q35.1-35.2(chr4:184406972-188915538)x3 copy number gain See cases [RCV000134158] Chr4:184406972..188915538 [GRCh38]
Chr4:185328126..189836692 [GRCh37]
Chr4:185565120..190073686 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:182437091-190018185)x1 copy number loss See cases [RCV000134276] Chr4:182437091..190018185 [GRCh38]
Chr4:183358244..190939340 [GRCh37]
Chr4:183595238..191176334 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q31.21-35.2(chr4:145042668-189975519)x3 copy number gain See cases [RCV000135845] Chr4:145042668..189975519 [GRCh38]
Chr4:145963820..190828225 [GRCh37]
Chr4:146183270..191133668 [NCBI36]
Chr4:4q31.21-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:180451652-190095391)x3 copy number gain See cases [RCV000135693] Chr4:180451652..190095391 [GRCh38]
Chr4:181372805..190828225 [GRCh37]
Chr4:181609799..191250527 [NCBI36]
Chr4:4q34.3-35.2		 likely pathogenic
GRCh38/hg38 4q34.1-35.2(chr4:173854560-189548183)x1 copy number loss See cases [RCV000136115] Chr4:173854560..189548183 [GRCh38]
Chr4:174775711..190469337 [GRCh37]
Chr4:175012286..190706331 [NCBI36]
Chr4:4q34.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:184239531-189975519)x1 copy number loss See cases [RCV000136942] Chr4:184239531..189975519 [GRCh38]
Chr4:185160684..190828225 [GRCh37]
Chr4:185397678..191133668 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:177985956-189975519)x1 copy number loss See cases [RCV000137101] Chr4:177985956..189975519 [GRCh38]
Chr4:178907110..190828225 [GRCh37]
Chr4:179144104..191133668 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q31.1-35.2(chr4:138510532-189963195)x3 copy number gain See cases [RCV000136810] Chr4:138510532..189963195 [GRCh38]
Chr4:139431686..190828225 [GRCh37]
Chr4:139651136..191121344 [NCBI36]
Chr4:4q31.1-35.2		 pathogenic
GRCh38/hg38 4q28.3-35.2(chr4:131985253-190095391)x3 copy number gain See cases [RCV000137721] Chr4:131985253..190095391 [GRCh38]
Chr4:132906408..190828225 [GRCh37]
Chr4:133125858..191250527 [NCBI36]
Chr4:4q28.3-35.2		 pathogenic|likely benign
GRCh38/hg38 4q32.3-35.2(chr4:166317587-190095391)x1 copy number loss See cases [RCV000137532] Chr4:166317587..190095391 [GRCh38]
Chr4:167238739..190828225 [GRCh37]
Chr4:167458189..191250527 [NCBI36]
Chr4:4q32.3-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:178014570-190095391)x1 copy number loss See cases [RCV000137343] Chr4:178014570..190095391 [GRCh38]
Chr4:178935724..190828225 [GRCh37]
Chr4:179172718..191250527 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:178549472-190095391)x1 copy number loss See cases [RCV000137262] Chr4:178549472..190095391 [GRCh38]
Chr4:179470626..190828225 [GRCh37]
Chr4:179707620..191250527 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:180574962-190095391)x1 copy number loss See cases [RCV000137345] Chr4:180574962..190095391 [GRCh38]
Chr4:181496115..190828225 [GRCh37]
Chr4:181733109..191250527 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:186037136-186271594)x1 copy number loss See cases [RCV000138100] Chr4:186037136..186271594 [GRCh38]
Chr4:186958290..187192748 [GRCh37]
Chr4:187195284..187429742 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q34.1-35.2(chr4:174150183-188259055)x1 copy number loss See cases [RCV000137925] Chr4:174150183..188259055 [GRCh38]
Chr4:175071334..189180209 [GRCh37]
Chr4:175307909..189417203 [NCBI36]
Chr4:4q34.1-35.2		 likely pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:183072743-190095391)x1 copy number loss See cases [RCV000138668] Chr4:183072743..190095391 [GRCh38]
Chr4:183993896..190828225 [GRCh37]
Chr4:184230890..191250527 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185790027-187829822)x4 copy number gain See cases [RCV000138568] Chr4:185790027..187829822 [GRCh38]
Chr4:186711181..188750976 [GRCh37]
Chr4:186948175..188987970 [NCBI36]
Chr4:4q35.1-35.2		 uncertain significance
GRCh38/hg38 4q33-35.2(chr4:169901205-190095391)x3 copy number gain See cases [RCV000138540] Chr4:169901205..190095391 [GRCh38]
Chr4:170822356..190828225 [GRCh37]
Chr4:171058931..191250527 [NCBI36]
Chr4:4q33-35.2		 uncertain significance
GRCh38/hg38 4q33-35.2(chr4:169873508-190018185)x1 copy number loss See cases [RCV000140396] Chr4:169873508..190018185 [GRCh38]
Chr4:170794659..190939340 [GRCh37]
Chr4:171031234..191176334 [NCBI36]
Chr4:4q33-35.2		 pathogenic
GRCh38/hg38 4q32.3-35.2(chr4:165281036-190018185)x1 copy number loss See cases [RCV000140414] Chr4:165281036..190018185 [GRCh38]
Chr4:166202188..190939340 [GRCh37]
Chr4:166421638..191176334 [NCBI36]
Chr4:4q32.3-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:179295511-190036318)x3 copy number gain See cases [RCV000140450] Chr4:179295511..190036318 [GRCh38]
Chr4:180216665..190957473 [GRCh37]
Chr4:180453659..191194467 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185698962-189975613)x1 copy number loss See cases [RCV000139618] Chr4:185698962..189975613 [GRCh38]
Chr4:186620116..190828225 [GRCh37]
Chr4:186857110..191133762 [NCBI36]
Chr4:4q35.1-35.2		 uncertain significance
GRCh38/hg38 4q35.1-35.2(chr4:184924265-186578389)x3 copy number gain See cases [RCV000141422] Chr4:184924265..186578389 [GRCh38]
Chr4:185845419..187499543 [GRCh37]
Chr4:186082413..187736537 [NCBI36]
Chr4:4q35.1-35.2		 pathogenic
GRCh38/hg38 4q32.1-35.2(chr4:160757699-190091407)x3 copy number gain See cases [RCV000140982] Chr4:160757699..190091407 [GRCh38]
Chr4:161678851..191012562 [GRCh37]
Chr4:161898301..191246543 [NCBI36]
Chr4:4q32.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185991833-186443602)x1 copy number loss See cases [RCV000140721] Chr4:185991833..186443602 [GRCh38]
Chr4:186912987..187364756 [GRCh37]
Chr4:187149981..187601750 [NCBI36]
Chr4:4q35.1-35.2		 uncertain significance
GRCh38/hg38 4q32.3-35.2(chr4:167373716-190036318)x1 copy number loss See cases [RCV000141964] Chr4:167373716..190036318 [GRCh38]
Chr4:168294867..190957473 [GRCh37]
Chr4:168531442..191194467 [NCBI36]
Chr4:4q32.3-35.2		 pathogenic
GRCh38/hg38 4q34.1-35.2(chr4:173989029-189975519)x1 copy number loss See cases [RCV000141490] Chr4:173989029..189975519 [GRCh38]
Chr4:174910180..190828225 [GRCh37]
Chr4:175146755..191133668 [NCBI36]
Chr4:4q34.1-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:182732498-187998523)x4 copy number gain See cases [RCV000141753] Chr4:182732498..187998523 [GRCh38]
Chr4:183653651..188919677 [GRCh37]
Chr4:183890645..189156671 [NCBI36]
Chr4:4q35.1-35.2		 likely pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185290811-187350114)x1 copy number loss See cases [RCV000141727] Chr4:185290811..187350114 [GRCh38]
Chr4:186211965..188271268 [GRCh37]
Chr4:186448959..188508262 [NCBI36]
Chr4:4q35.1-35.2		 likely benign
GRCh38/hg38 4q32.3-35.2(chr4:168970400-186936738)x1 copy number loss See cases [RCV000142368] Chr4:168970400..186936738 [GRCh38]
Chr4:169891551..187857892 [GRCh37]
Chr4:170128126..188094886 [NCBI36]
Chr4:4q32.3-35.2		 pathogenic
GRCh38/hg38 4q34.1-35.2(chr4:172501374-190095332)x1 copy number loss See cases [RCV000143079] Chr4:172501374..190095332 [GRCh38]
Chr4:173422525..190828225 [GRCh37]
Chr4:173659100..191250468 [NCBI36]
Chr4:4q34.1-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:180717850-190095391)x3 copy number gain See cases [RCV000143010] Chr4:180717850..190095391 [GRCh38]
Chr4:181639003..190828225 [GRCh37]
Chr4:181875997..191250527 [NCBI36]
Chr4:4q34.3-35.2		 pathogenic|likely benign
GRCh38/hg38 4q32.3-35.2(chr4:168119317-190095391)x3 copy number gain See cases [RCV000143331] Chr4:168119317..190095391 [GRCh38]
Chr4:169040468..190828225 [GRCh37]
Chr4:169277043..191250527 [NCBI36]
Chr4:4q32.3-35.2		 pathogenic
GRCh38/hg38 4q33-35.2(chr4:170899124-190036318)x1 copy number loss See cases [RCV000143232] Chr4:170899124..190036318 [GRCh38]
Chr4:171820275..190957473 [GRCh37]
Chr4:172056850..191194467 [NCBI36]
Chr4:4q33-35.2		 pathogenic
GRCh38/hg38 4q34.3-35.2(chr4:176756632-189621964)x1 copy number loss See cases [RCV000143626] Chr4:176756632..189621964 [GRCh38]
Chr4:177677786..190543118 [GRCh37]
Chr4:177914780..190780112 [NCBI36]
Chr4:4q34.3-35.2		 likely pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:186008491-186212590)x4 copy number gain See cases [RCV000143468] Chr4:186008491..186212590 [GRCh38]
Chr4:186929645..187133744 [GRCh37]
Chr4:187166639..187370738 [NCBI36]
Chr4:4q35.1-35.2		 likely benign|uncertain significance
GRCh38/hg38 4q28.3-35.2(chr4:134935616-190036318)x3 copy number gain See cases [RCV000143559] Chr4:134935616..190036318 [GRCh38]
Chr4:135856771..190957473 [GRCh37]
Chr4:136076221..191194467 [NCBI36]
Chr4:4q28.3-35.2		 pathogenic
GRCh38/hg38 4q35.1-35.2(chr4:185601825-187530334)x3 copy number gain See cases [RCV000143575] Chr4:185601825..187530334 [GRCh38]
Chr4:186522979..188451488 [GRCh37]
Chr4:186759973..188688482 [NCBI36]
Chr4:4q35.1-35.2		 uncertain significance
GRCh38/hg38 4q34.3-35.1(chr4:181579626-186100199)x1 copy number loss See cases [RCV000148272] Chr4:181579626..186100199 [GRCh38]
Chr4:182500779..187021353 [GRCh37]
Chr4:182737773..187258347 [NCBI36]
Chr4:4q34.3-35.1		 pathogenic
GRCh37/hg19 4q34.1-35.2(chr4:176270886-190713650)x1 copy number loss See cases [RCV000239790] Chr4:176270886..190713650 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
NC_000004.12:g.(?_186013132)_(186215992_?)dup duplication Autism spectrum disorder [RCV000208739] Chr4:186013132..186215992 [GRCh38]
Chr4:186934286..187137146 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q34.3-35.2(chr4:178243625-190713650)x1 copy number loss See cases [RCV000239851] Chr4:178243625..190713650 [GRCh37]
Chr4:4q34.3-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:185941418-189180194)x1 copy number loss See cases [RCV000240072] Chr4:185941418..189180194 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q26-35.2(chr4:119437495-190904301)x3 copy number gain See cases [RCV000240392] Chr4:119437495..190904301 [GRCh37]
Chr4:4q26-35.2		 pathogenic
NM_003265.3(TLR3):c.1677G>A (p.Lys559=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000548139] Chr4:186083363 [GRCh38]
Chr4:187004517 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.2553C>T (p.Phe851=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000553385] Chr4:186084711 [GRCh38]
Chr4:187005865 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.1079T>C (p.Leu360Pro) single nucleotide variant Immunodeficiency 83, susceptibility to viral infections [RCV000586170] Chr4:186082765 [GRCh38]
Chr4:187003919 [GRCh37]
Chr4:4q35.1		 risk factor
NM_003265.3(TLR3):c.2600G>A (p.Arg867Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001440832]|Immunodeficiency 83, susceptibility to viral infections [RCV000587136] Chr4:186084758 [GRCh38]
Chr4:187005912 [GRCh37]
Chr4:4q35.1		 risk factor|likely benign
GRCh37/hg19 4q35.1-35.2(chr4:185381293-190957473)x1 copy number loss See cases [RCV000449363] Chr4:185381293..190957473 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:185253508-190713591)x1 copy number loss See cases [RCV000449221] Chr4:185253508..190713591 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q34.1-35.2(chr4:175550289-190838582)x1 copy number loss See cases [RCV000446613] Chr4:175550289..190838582 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
GRCh37/hg19 4q32.3-35.2(chr4:167413365-190957473)x1 copy number loss See cases [RCV000446115] Chr4:167413365..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:185978583-188762387)x3 copy number gain See cases [RCV000446235] Chr4:185978583..188762387 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q35.1(chr4:186581661-187074987)x3 copy number gain See cases [RCV000446644] Chr4:186581661..187074987 [GRCh37]
Chr4:4q35.1		 likely benign
GRCh37/hg19 4q32.3-35.2(chr4:166735148-190957473)x3 copy number gain See cases [RCV000446531] Chr4:166735148..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:186252440-190713591)x1 copy number loss See cases [RCV000446459] Chr4:186252440..190713591 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q34.1-35.2(chr4:175749001-190957473)x1 copy number loss See cases [RCV000445881] Chr4:175749001..190957473 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
GRCh37/hg19 4q34.1-35.2(chr4:175550289-190957473)x1 copy number loss See cases [RCV000448048] Chr4:175550289..190957473 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
NM_003265.3(TLR3):c.1377C>T (p.Phe459=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001514931]|not provided [RCV001692126]|not specified [RCV000454544] Chr4:186083063 [GRCh38]
Chr4:187004217 [GRCh37]
Chr4:4q35.1		 benign
GRCh37/hg19 4q35.1-35.2(chr4:184852835-190957473)x1 copy number loss See cases [RCV000512074] Chr4:184852835..190957473 [GRCh37]
Chr4:4q35.1-35.2		 likely pathogenic
NM_003265.3(TLR3):c.919T>G (p.Tyr307Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000554243] Chr4:186082605 [GRCh38]
Chr4:187003759 [GRCh37]
Chr4:4q35.1		 benign
GRCh37/hg19 4q32.3-35.2(chr4:166436844-190957473)x3 copy number gain See cases [RCV000510222] Chr4:166436844..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:185958310-189223175)x3 copy number gain See cases [RCV000510660] Chr4:185958310..189223175 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q31.3-35.2(chr4:153890440-190957473)x3 copy number gain See cases [RCV000510713] Chr4:153890440..190957473 [GRCh37]
Chr4:4q31.3-35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q25-35.2(chr4:109199664-189752726)x3 copy number gain See cases [RCV000511945] Chr4:109199664..189752726 [GRCh37]
Chr4:4q25-35.2		 pathogenic
GRCh37/hg19 4q22.1-35.2(chr4:93071152-190957473)x3 copy number gain See cases [RCV000510970] Chr4:93071152..190957473 [GRCh37]
Chr4:4q22.1-35.2		 pathogenic
GRCh37/hg19 4q34.2-35.2(chr4:176306103-190957473)x3 copy number gain See cases [RCV000511078] Chr4:176306103..190957473 [GRCh37]
Chr4:4q34.2-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:186349585-190957473)x1 copy number loss See cases [RCV000510959] Chr4:186349585..190957473 [GRCh37]
Chr4:4q35.1-35.2		 likely pathogenic
NM_003265.3(TLR3):c.2265A>G (p.Glu755=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000540763] Chr4:186083951 [GRCh38]
Chr4:187005105 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2556T>G (p.Leu852=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647021] Chr4:186084714 [GRCh38]
Chr4:187005868 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.838G>A (p.Asp280Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647022] Chr4:186082524 [GRCh38]
Chr4:187003678 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.1834C>T (p.Leu612=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647023] Chr4:186083520 [GRCh38]
Chr4:187004674 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.957C>A (p.His319Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647024]|not specified [RCV004025720] Chr4:186082643 [GRCh38]
Chr4:187003797 [GRCh37]
Chr4:4q35.1		 likely benign|uncertain significance
NM_003265.3(TLR3):c.2079A>C (p.Thr693=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647030] Chr4:186083765 [GRCh38]
Chr4:187004919 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2011C>T (p.Leu671=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647032] Chr4:186083697 [GRCh38]
Chr4:187004851 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.165G>A (p.Val55=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001484660] Chr4:186076784 [GRCh38]
Chr4:186997938 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.727T>C (p.Leu243=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000541647]|not provided [RCV004546518] Chr4:186082413 [GRCh38]
Chr4:187003567 [GRCh37]
Chr4:4q35.1		 benign|likely benign
NM_003265.3(TLR3):c.671T>A (p.Phe224Tyr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003779920]|not specified [RCV004301117] Chr4:186082357 [GRCh38]
Chr4:187003511 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.889C>G (p.Leu297Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647014]|Immunodeficiency 83, susceptibility to viral infections [RCV000587900]|Multisystem inflammatory syndrome in children [RCV001779020] Chr4:186082575 [GRCh38]
Chr4:187003729 [GRCh37]
Chr4:4q35.1		 risk factor|likely benign|uncertain significance
NM_003265.3(TLR3):c.2236G>T (p.Glu746Ter) single nucleotide variant Immunodeficiency 83, susceptibility to viral infections [RCV000590389] Chr4:186083922 [GRCh38]
Chr4:187005076 [GRCh37]
Chr4:4q35.1		 risk factor
NM_003265.3(TLR3):c.1716C>T (p.Asn572=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001853712] Chr4:186083402 [GRCh38]
Chr4:187004556 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.958G>A (p.Gly320Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647013] Chr4:186082644 [GRCh38]
Chr4:187003798 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1489A>G (p.Ser497Gly) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647015] Chr4:186083175 [GRCh38]
Chr4:187004329 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2497C>T (p.His833Tyr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647017] Chr4:186084655 [GRCh38]
Chr4:187005809 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.634-10C>A single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000647019]|TLR3-related disorder [RCV003980254]|not provided [RCV001702539] Chr4:186082310 [GRCh38]
Chr4:187003464 [GRCh37]
Chr4:4q35.1		 benign|likely benign
GRCh37/hg19 4q34.3-35.2(chr4:180702769-190957473)x3 copy number gain See cases [RCV000512153] Chr4:180702769..190957473 [GRCh37]
Chr4:4q34.3-35.2		 pathogenic
GRCh37/hg19 4q32.1-35.2(chr4:156465633-190957473)x3 copy number gain See cases [RCV000512542] Chr4:156465633..190957473 [GRCh37]
Chr4:4q32.1-35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q32.3-35.2(chr4:169969014-190957473)x1 copy number loss not provided [RCV000682484] Chr4:169969014..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
GRCh37/hg19 4q34.1-35.2(chr4:175709188-190957473)x1 copy number loss not provided [RCV000682492] Chr4:175709188..190957473 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:185017749-190957473)x3 copy number gain not provided [RCV000682497] Chr4:185017749..190957473 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:186496069-189142432)x3 copy number gain not provided [RCV000682499] Chr4:186496069..189142432 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q32.1-35.2(chr4:159492464-190957473)x3 copy number gain not provided [RCV000682478] Chr4:159492464..190957473 [GRCh37]
Chr4:4q32.1-35.2		 pathogenic
GRCh37/hg19 4q34.3-35.2(chr4:178771936-190957473)x3 copy number gain not provided [RCV000682495] Chr4:178771936..190957473 [GRCh37]
Chr4:4q34.3-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:186555741-187379745)x1 copy number loss not provided [RCV000682500] Chr4:186555741..187379745 [GRCh37]
Chr4:4q35.1-35.2		 likely pathogenic
Single allele deletion not provided [RCV000677918] Chr4:176270886..190713650 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
GRCh37/hg19 4q34.2-35.2(chr4:176493246-190957473)x1 copy number loss not provided [RCV000682493] Chr4:176493246..190957473 [GRCh37]
Chr4:4q34.2-35.2		 pathogenic
NM_003265.3(TLR3):c.655G>A (p.Ala219Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000688142] Chr4:186082341 [GRCh38]
Chr4:187003495 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2693G>A (p.Gly898Glu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000684924] Chr4:186084851 [GRCh38]
Chr4:187006005 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1471G>A (p.Ala491Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000692710] Chr4:186083157 [GRCh38]
Chr4:187004311 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.554C>T (p.Ala185Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000691916]|Susceptibility to HIV infection [RCV003224374] Chr4:186078952 [GRCh38]
Chr4:187000106 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1854del (p.Lys619fs) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV000702041] Chr4:186083540 [GRCh38]
Chr4:187004694 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.176C>A (p.Thr59Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000690308]|Susceptibility to HIV infection [RCV002499225] Chr4:186076795 [GRCh38]
Chr4:186997949 [GRCh37]
Chr4:4q35.1		 uncertain significance
NC_000004.11:g.(?_186997754)_(187006047_?)dup duplication Herpes simplex encephalitis, susceptibility to, 1 [RCV000707799] Chr4:186076600..186084893 [GRCh38]
Chr4:186997754..187006047 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2228G>A (p.Gly743Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000691555] Chr4:186083914 [GRCh38]
Chr4:187005068 [GRCh37]
Chr4:4q35.1		 uncertain significance
Single allele duplication Autism [RCV000754289] Chr4:185324779..188495308 [GRCh38]
Chr4:4q35.1-35.2		 likely pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q34.3-35.2(chr4:183157313-191028879)x1 copy number loss not provided [RCV000744206] Chr4:183157313..191028879 [GRCh37]
Chr4:4q34.3-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:184040122-187880098)x3 copy number gain not provided [RCV000744219] Chr4:184040122..187880098 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:185137253-190915650)x1 copy number loss not provided [RCV000744226] Chr4:185137253..190915650 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:186953813-187201271)x1 copy number loss not provided [RCV000744246] Chr4:186953813..187201271 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q35.1(chr4:186983342-187054136)x3 copy number gain not provided [RCV000744247] Chr4:186983342..187054136 [GRCh37]
Chr4:4q35.1		 benign
GRCh37/hg19 4q35.1(chr4:186997767-187021315)x3 copy number gain not provided [RCV000744248] Chr4:186997767..187021315 [GRCh37]
Chr4:4q35.1		 benign
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
NM_003265.3(TLR3):c.1987G>A (p.Glu663Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001045314]|not specified [RCV004031395] Chr4:186083673 [GRCh38]
Chr4:187004827 [GRCh37]
Chr4:4q35.1		 likely benign|uncertain significance
NM_003265.3(TLR3):c.2664C>T (p.Ala888=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000885249]|TLR3-related disorder [RCV003968033] Chr4:186084822 [GRCh38]
Chr4:187005976 [GRCh37]
Chr4:4q35.1		 benign|likely benign
NM_003265.3(TLR3):c.1295A>G (p.His432Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000923258] Chr4:186082981 [GRCh38]
Chr4:187004135 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.735A>G (p.Leu245=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001469372] Chr4:186082421 [GRCh38]
Chr4:187003575 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1585C>T (p.Leu529Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000924250]|not provided [RCV001356067] Chr4:186083271 [GRCh38]
Chr4:187004425 [GRCh37]
Chr4:4q35.1		 likely benign|uncertain significance
NM_003265.3(TLR3):c.612G>A (p.Leu204=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000968899]|TLR3-related disorder [RCV003962857] Chr4:186079010 [GRCh38]
Chr4:187000164 [GRCh37]
Chr4:4q35.1		 benign|likely benign
NM_003265.3(TLR3):c.798A>G (p.Thr266=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000982316] Chr4:186082484 [GRCh38]
Chr4:187003638 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2710C>T (p.His904Tyr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001062497]|not specified [RCV004030458] Chr4:186084868 [GRCh38]
Chr4:187006022 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1559A>G (p.Asn520Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000792859] Chr4:186083245 [GRCh38]
Chr4:187004399 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q34.1-35.2(chr4:174610492-190427545) copy number loss not provided [RCV000767793] Chr4:174610492..190427545 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
NM_003265.3(TLR3):c.2217T>C (p.His739=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000964978]|not provided [RCV003438634] Chr4:186083903 [GRCh38]
Chr4:187005057 [GRCh37]
Chr4:4q35.1		 benign|likely benign
NM_003265.3(TLR3):c.1740G>A (p.Glu580=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001410960] Chr4:186083426 [GRCh38]
Chr4:187004580 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1296C>T (p.His432=) single nucleotide variant not provided [RCV000923654] Chr4:186082982 [GRCh38]
Chr4:187004136 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1683G>A (p.Leu561=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000921403] Chr4:186083369 [GRCh38]
Chr4:187004523 [GRCh37]
Chr4:4q35.1		 benign
GRCh37/hg19 4q33-35.2(chr4:171663620-190431429) copy number loss not provided [RCV000767673] Chr4:171663620..190431429 [GRCh37]
Chr4:4q33-35.2		 pathogenic
GRCh37/hg19 4q32.3-35.2(chr4:166623890-190957473)x1 copy number loss not provided [RCV000845722] Chr4:166623890..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
NM_003265.3(TLR3):c.1928G>A (p.Arg643His) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000797613] Chr4:186083614 [GRCh38]
Chr4:187004768 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2371A>G (p.Arg791Gly) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000794791] Chr4:186084057 [GRCh38]
Chr4:187005211 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:186925106-187129431)x3 copy number gain not provided [RCV000849830] Chr4:186925106..187129431 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q34.3-35.2(chr4:179996712-190957473)x1 copy number loss not provided [RCV000849865] Chr4:179996712..190957473 [GRCh37]
Chr4:4q34.3-35.2		 pathogenic
NM_003265.3(TLR3):c.1234C>G (p.Leu412Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000813289] Chr4:186082920 [GRCh38]
Chr4:187004074 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.585del (p.Asn196fs) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV000817148] Chr4:186078982 [GRCh38]
Chr4:187000136 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.71C>T (p.Ser24Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000801422] Chr4:186076690 [GRCh38]
Chr4:186997844 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.205G>A (p.Ala69Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000824342] Chr4:186076824 [GRCh38]
Chr4:186997978 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1072G>A (p.Glu358Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000798202] Chr4:186082758 [GRCh38]
Chr4:187003912 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.442-6C>G single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000812537] Chr4:186078834 [GRCh38]
Chr4:186999988 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.266A>C (p.Lys89Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000812780] Chr4:186076885 [GRCh38]
Chr4:186998039 [GRCh37]
Chr4:4q35.1		 uncertain significance
NC_000004.12:g.(?_185684754)_(186709827_?)del deletion not provided [RCV000798147] Chr4:185684754..186709827 [GRCh38]
Chr4:186605908..187630981 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
NM_003265.3(TLR3):c.1378G>A (p.Glu460Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000792842] Chr4:186083064 [GRCh38]
Chr4:187004218 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2654G>A (p.Arg885Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000802044]|not specified [RCV004028088] Chr4:186084812 [GRCh38]
Chr4:187005966 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2384C>T (p.Ala795Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000808130] Chr4:186084070 [GRCh38]
Chr4:187005224 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1774G>A (p.Asp592Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000794530] Chr4:186083460 [GRCh38]
Chr4:187004614 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1430C>T (p.Ala477Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000800885] Chr4:186083116 [GRCh38]
Chr4:187004270 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q32.3-35.2(chr4:169607746-190957473)x3 copy number gain not provided [RCV000847360] Chr4:169607746..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
GRCh37/hg19 4q34.2-35.2(chr4:177189906-190816266)x1 copy number loss not provided [RCV000846268] Chr4:177189906..190816266 [GRCh37]
Chr4:4q34.2-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:185785184-188207908)x3 copy number gain not provided [RCV001005631] Chr4:185785184..188207908 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:186950482-187204447)x1 copy number loss not provided [RCV000846394] Chr4:186950482..187204447 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:186925106-187135487)x3 copy number gain not provided [RCV000846403] Chr4:186925106..187135487 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:184648532-190957473)x1 copy number loss not provided [RCV000846185] Chr4:184648532..190957473 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q34.3-35.2(chr4:179752903-187987047)x3 copy number gain not provided [RCV001005627] Chr4:179752903..187987047 [GRCh37]
Chr4:4q34.3-35.2		 pathogenic
GRCh37/hg19 4q31.3-35.2(chr4:151174061-190957473)x3 copy number gain not provided [RCV000849098] Chr4:151174061..190957473 [GRCh37]
Chr4:4q31.3-35.2		 pathogenic
NM_003265.3(TLR3):c.343del (p.Ser115fs) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV001237595] Chr4:186076960 [GRCh38]
Chr4:186998114 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1385A>T (p.Tyr462Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001224743] Chr4:186083071 [GRCh38]
Chr4:187004225 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.499C>T (p.Gln167Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001225905] Chr4:186078897 [GRCh38]
Chr4:187000051 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:183245174-190948359)x1 copy number loss not provided [RCV000998343] Chr4:183245174..190948359 [GRCh37]
Chr4:4q35.1-35.2		 likely pathogenic
NM_003265.3(TLR3):c.634-10C>T single nucleotide variant not provided [RCV000949707] Chr4:186082310 [GRCh38]
Chr4:187003464 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.634-7C>T single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002547197] Chr4:186082313 [GRCh38]
Chr4:187003467 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.634-6C>T single nucleotide variant not provided [RCV000949709] Chr4:186082314 [GRCh38]
Chr4:187003468 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.900A>G (p.Leu300=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000941513] Chr4:186082586 [GRCh38]
Chr4:187003740 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1986C>T (p.Asn662=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001443070] Chr4:186083672 [GRCh38]
Chr4:187004826 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.442-8C>T single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000976275] Chr4:186078832 [GRCh38]
Chr4:186999986 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.972G>T (p.Val324=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001426159] Chr4:186082658 [GRCh38]
Chr4:187003812 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.44T>G (p.Leu15Trp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000886990] Chr4:186076663 [GRCh38]
Chr4:186997817 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.634-8A>T single nucleotide variant not provided [RCV000948689] Chr4:186082312 [GRCh38]
Chr4:187003466 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1284T>G (p.Ser428=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV000887798] Chr4:186082970 [GRCh38]
Chr4:187004124 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.2680C>A (p.Gln894Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001227082] Chr4:186084838 [GRCh38]
Chr4:187005992 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1510C>G (p.Pro504Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001231953] Chr4:186083196 [GRCh38]
Chr4:187004350 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2068C>A (p.Leu690Ile) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001227356] Chr4:186083754 [GRCh38]
Chr4:187004908 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2102C>T (p.Pro701Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001234605] Chr4:186083788 [GRCh38]
Chr4:187004942 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2615A>G (p.Lys872Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001206683] Chr4:186084773 [GRCh38]
Chr4:187005927 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1984A>C (p.Asn662His) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001046124] Chr4:186083670 [GRCh38]
Chr4:187004824 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1142T>C (p.Leu381Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001217990] Chr4:186082828 [GRCh38]
Chr4:187003982 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q34.3-35.2(chr4:178566256-190957473)x1 copy number loss not provided [RCV001005626] Chr4:178566256..190957473 [GRCh37]
Chr4:4q34.3-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:183694501-190957473)x1 copy number loss not provided [RCV002472626] Chr4:183694501..190957473 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
NM_003265.3(TLR3):c.1028T>C (p.Leu343Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001049024] Chr4:186082714 [GRCh38]
Chr4:187003868 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.755A>G (p.Asn252Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001035573] Chr4:186082441 [GRCh38]
Chr4:187003595 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.874G>A (p.Asp292Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001067331] Chr4:186082560 [GRCh38]
Chr4:187003714 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.458A>C (p.Asp153Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001046126] Chr4:186078856 [GRCh38]
Chr4:187000010 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2405C>A (p.Ala802Glu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001047929] Chr4:186084091 [GRCh38]
Chr4:187005245 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2164C>G (p.Leu722Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001207347] Chr4:186083850 [GRCh38]
Chr4:187005004 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1488T>A (p.Asp496Glu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001041562] Chr4:186083174 [GRCh38]
Chr4:187004328 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.157A>C (p.Ile53Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001056449] Chr4:186076776 [GRCh38]
Chr4:186997930 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2015C>G (p.Ser672Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001217714] Chr4:186083701 [GRCh38]
Chr4:187004855 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.242A>G (p.Asp81Gly) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001247828] Chr4:186076861 [GRCh38]
Chr4:186998015 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1927C>T (p.Arg643Cys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001040608] Chr4:186083613 [GRCh38]
Chr4:187004767 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.467A>G (p.His156Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001228496] Chr4:186078865 [GRCh38]
Chr4:187000019 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.994T>C (p.Ser332Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001205518] Chr4:186082680 [GRCh38]
Chr4:187003834 [GRCh37]
Chr4:4q35.1		 uncertain significance
NC_000004.12:g.(?_186076620)_(186210641_?)dup duplication not provided [RCV001033024] Chr4:186997774..187131795 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q32.3-35.2(chr4:165010461-190957473)x1 copy number loss not provided [RCV001005612] Chr4:165010461..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
NM_003265.3(TLR3):c.1012A>G (p.Ile338Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001050976] Chr4:186082698 [GRCh38]
Chr4:187003852 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.851A>T (p.Asn284Ile) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001052136] Chr4:186082537 [GRCh38]
Chr4:187003691 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1986C>G (p.Asn662Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001056644] Chr4:186083672 [GRCh38]
Chr4:187004826 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2516C>A (p.Ala839Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001063073]|not specified [RCV004030479] Chr4:186084674 [GRCh38]
Chr4:187005828 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1613A>C (p.Gln538Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001048903] Chr4:186083299 [GRCh38]
Chr4:187004453 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.109T>C (p.Cys37Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001228863] Chr4:186076728 [GRCh38]
Chr4:186997882 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1177T>A (p.Leu393Met) single nucleotide variant not specified [RCV004684148] Chr4:186082863 [GRCh38]
Chr4:187004017 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2039C>T (p.Pro680Leu) single nucleotide variant Immunodeficiency 83, susceptibility to viral infections [RCV001533543] Chr4:186083725 [GRCh38]
Chr4:187004879 [GRCh37]
Chr4:4q35.1		 risk factor
NM_003265.3(TLR3):c.628A>G (p.Lys210Glu) single nucleotide variant not specified [RCV004684151] Chr4:186079026 [GRCh38]
Chr4:187000180 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q34.3-35.2(chr4:179554876-190916678) copy number loss Atypical behavior [RCV001291982] Chr4:179554876..190916678 [GRCh37]
Chr4:4q34.3-35.2		 likely pathogenic
NM_003265.3(TLR3):c.597A>T (p.Leu199Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002568915]|Immunodeficiency 83, susceptibility to viral infections [RCV001533542]|not provided [RCV001815586] Chr4:186078995 [GRCh38]
Chr4:187000149 [GRCh37]
Chr4:4q35.1		 risk factor|uncertain significance
GRCh37/hg19 4q35.1(chr4:186858293-187097385)x1 copy number loss not provided [RCV001258669] Chr4:186858293..187097385 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1884G>C (p.Lys628Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001306817] Chr4:186083570 [GRCh38]
Chr4:187004724 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.448A>T (p.Ile150Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001301512] Chr4:186078846 [GRCh38]
Chr4:187000000 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1528A>G (p.Ile510Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001319374]|not specified [RCV004034967] Chr4:186083214 [GRCh38]
Chr4:187004368 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.368C>T (p.Thr123Met) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001342311] Chr4:186076987 [GRCh38]
Chr4:186998141 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.415A>T (p.Lys139Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001308872] Chr4:186077034 [GRCh38]
Chr4:186998188 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.392T>C (p.Met131Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001319922] Chr4:186077011 [GRCh38]
Chr4:186998165 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1468G>T (p.Val490Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001349773]|not specified [RCV004681135] Chr4:186083154 [GRCh38]
Chr4:187004308 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.86C>T (p.Thr29Ile) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001318314] Chr4:186076705 [GRCh38]
Chr4:186997859 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1015T>G (p.Ser339Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001341120]|TLR3-related disorder [RCV003399127] Chr4:186082701 [GRCh38]
Chr4:187003855 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.259A>G (p.Ile87Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001337790] Chr4:186076878 [GRCh38]
Chr4:186998032 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1383C>T (p.Ile461=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001397662] Chr4:186083069 [GRCh38]
Chr4:187004223 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.653A>G (p.His218Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001317246] Chr4:186082339 [GRCh38]
Chr4:187003493 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.333A>G (p.Leu111=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001433444] Chr4:186076952 [GRCh38]
Chr4:186998106 [GRCh37]
Chr4:4q35.1		 likely benign
NC_000004.11:g.(?_186997774)_(187630981_?)del deletion not provided [RCV001383167] Chr4:186997774..187630981 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
NM_003265.3(TLR3):c.165G>C (p.Val55=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001422450] Chr4:186076784 [GRCh38]
Chr4:186997938 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.952_953del (p.Leu318fs) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV001294312] Chr4:186082637..186082638 [GRCh38]
Chr4:187003791..187003792 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2324C>A (p.Ser775Tyr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001317657] Chr4:186084010 [GRCh38]
Chr4:187005164 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.293T>A (p.Leu98His) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001318437] Chr4:186076912 [GRCh38]
Chr4:186998066 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2059C>G (p.Pro687Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001371177] Chr4:186083745 [GRCh38]
Chr4:187004899 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2260T>C (p.Phe754Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001297890] Chr4:186083946 [GRCh38]
Chr4:187005100 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2158G>A (p.Val720Ile) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001321841] Chr4:186083844 [GRCh38]
Chr4:187004998 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1140C>A (p.Asn380Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001344910] Chr4:186082826 [GRCh38]
Chr4:187003980 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.17C>T (p.Pro6Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001359457] Chr4:186076636 [GRCh38]
Chr4:186997790 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2051A>G (p.His684Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001338767] Chr4:186083737 [GRCh38]
Chr4:187004891 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.749T>C (p.Ile250Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001346902] Chr4:186082435 [GRCh38]
Chr4:187003589 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2426G>A (p.Arg809Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001338082]|not specified [RCV004035854] Chr4:186084112 [GRCh38]
Chr4:187005266 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1684T>C (p.Ser562Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001309850]|not specified [RCV004034216] Chr4:186083370 [GRCh38]
Chr4:187004524 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2711A>T (p.His904Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001346126] Chr4:186084869 [GRCh38]
Chr4:187006023 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2599C>T (p.Arg867Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001298372]|Immunodeficiency 83, susceptibility to viral infections [RCV001810019] Chr4:186084757 [GRCh38]
Chr4:187005911 [GRCh37]
Chr4:4q35.1		 likely pathogenic|uncertain significance
NM_003265.3(TLR3):c.1181G>A (p.Arg394Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001339110] Chr4:186082867 [GRCh38]
Chr4:187004021 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1891G>A (p.Gly631Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001302277]|not specified [RCV004036234] Chr4:186083577 [GRCh38]
Chr4:187004731 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1546A>G (p.Asn516Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001361893]|not specified [RCV004036816] Chr4:186083232 [GRCh38]
Chr4:187004386 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2291A>G (p.Tyr764Cys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001325957] Chr4:186083977 [GRCh38]
Chr4:187005131 [GRCh37]
Chr4:4q35.1		 uncertain significance
NC_000004.11:g.(?_186997754)_(187006047_?)dup duplication Herpes simplex encephalitis 1 [RCV001319582] Chr4:186997754..187006047 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.934C>A (p.His312Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001364542] Chr4:186082620 [GRCh38]
Chr4:187003774 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.821C>T (p.Thr274Ile) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001360541] Chr4:186082507 [GRCh38]
Chr4:187003661 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.24C>T (p.Ile8=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001394987] Chr4:186076643 [GRCh38]
Chr4:186997797 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2542A>C (p.Ile848Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001307483] Chr4:186084700 [GRCh38]
Chr4:187005854 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1976A>G (p.Asn659Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001309905] Chr4:186083662 [GRCh38]
Chr4:187004816 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.633G>C (p.Glu211Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001298516] Chr4:186079031 [GRCh38]
Chr4:187000185 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1231A>G (p.Ile411Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001359231] Chr4:186082917 [GRCh38]
Chr4:187004071 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.72C>T (p.Ser24=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001485473] Chr4:186076691 [GRCh38]
Chr4:186997845 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.705C>G (p.Pro235=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001438539] Chr4:186082391 [GRCh38]
Chr4:187003545 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.-7C>A single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001515649]|not specified [RCV003487346] Chr4:186076613 [GRCh38]
Chr4:186997767 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.238T>C (p.Leu80=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001482172] Chr4:186076857 [GRCh38]
Chr4:186998011 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2502T>C (p.His834=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001484948] Chr4:186084660 [GRCh38]
Chr4:187005814 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.453A>G (p.Thr151=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001476637] Chr4:186078851 [GRCh38]
Chr4:187000005 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.717G>A (p.Glu239=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001466426] Chr4:186082403 [GRCh38]
Chr4:187003557 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.753G>A (p.Arg251=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001474349] Chr4:186082439 [GRCh38]
Chr4:187003593 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1773C>T (p.Ile591=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001403446] Chr4:186083459 [GRCh38]
Chr4:187004613 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2382G>A (p.Glu794=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001403865] Chr4:186084068 [GRCh38]
Chr4:187005222 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2523A>G (p.Glu841=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001432884] Chr4:186084681 [GRCh38]
Chr4:187005835 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1890C>T (p.Phe630=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001444037] Chr4:186083576 [GRCh38]
Chr4:187004730 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.39C>T (p.Gly13=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001425028] Chr4:186076658 [GRCh38]
Chr4:186997812 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1779A>G (p.Leu593=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001439908] Chr4:186083465 [GRCh38]
Chr4:187004619 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2400A>G (p.Leu800=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001417269] Chr4:186084086 [GRCh38]
Chr4:187005240 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.957C>T (p.His319=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001418428] Chr4:186082643 [GRCh38]
Chr4:187003797 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.450C>T (p.Ile150=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001403795] Chr4:186078848 [GRCh38]
Chr4:187000002 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2592C>T (p.Leu864=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001447455] Chr4:186084750 [GRCh38]
Chr4:187005904 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1605C>T (p.Leu535=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001447907] Chr4:186083291 [GRCh38]
Chr4:187004445 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.346G>A (p.Asp116Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001455117] Chr4:186076965 [GRCh38]
Chr4:186998119 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2487-4T>C single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001503047] Chr4:186084641 [GRCh38]
Chr4:187005795 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.66A>G (p.Ala22=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001405503] Chr4:186076685 [GRCh38]
Chr4:186997839 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.387T>C (p.His129=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001470480] Chr4:186077006 [GRCh38]
Chr4:186998160 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2224C>T (p.Leu742Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001523448]|Immunodeficiency 83, susceptibility to viral infections [RCV001533544] Chr4:186083910 [GRCh38]
Chr4:187005064 [GRCh37]
Chr4:4q35.1		 risk factor|benign
NM_003265.3(TLR3):c.2385G>T (p.Ala795=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001485362] Chr4:186084071 [GRCh38]
Chr4:187005225 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2172C>T (p.His724=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001435434] Chr4:186083858 [GRCh38]
Chr4:187005012 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.39C>A (p.Gly13=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001456547] Chr4:186076658 [GRCh38]
Chr4:186997812 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.805T>C (p.Leu269=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001495456] Chr4:186082491 [GRCh38]
Chr4:187003645 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2590C>G (p.Leu864Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001930085] Chr4:186084748 [GRCh38]
Chr4:187005902 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2672A>G (p.His891Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001930096] Chr4:186084830 [GRCh38]
Chr4:187005984 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.295C>G (p.Pro99Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001874031]|not specified [RCV004038986] Chr4:186076914 [GRCh38]
Chr4:186998068 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2284C>A (p.His762Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002007690] Chr4:186083970 [GRCh38]
Chr4:187005124 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2186G>A (p.Arg729Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002008763] Chr4:186083872 [GRCh38]
Chr4:187005026 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1173A>C (p.Thr391=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002025872] Chr4:186082859 [GRCh38]
Chr4:187004013 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1007A>G (p.Gln336Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002007794] Chr4:186082693 [GRCh38]
Chr4:187003847 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1301A>G (p.Glu434Gly) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001896459] Chr4:186082987 [GRCh38]
Chr4:187004141 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2678T>C (p.Leu893Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002023265] Chr4:186084836 [GRCh38]
Chr4:187005990 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.787A>G (p.Thr263Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001914556] Chr4:186082473 [GRCh38]
Chr4:187003627 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.903A>G (p.Glu301=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001985268] Chr4:186082589 [GRCh38]
Chr4:187003743 [GRCh37]
Chr4:4q35.1		 likely benign
GRCh37/hg19 4q32.1-35.2(chr4:159755174-190225765) copy number gain not specified [RCV002053465] Chr4:159755174..190225765 [GRCh37]
Chr4:4q32.1-35.2		 pathogenic
GRCh37/hg19 4q34.1-35.2(chr4:175855408-190957473) copy number gain not specified [RCV002053471] Chr4:175855408..190957473 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:183221828-190957473) copy number loss not specified [RCV002053473] Chr4:183221828..190957473 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
NM_003265.3(TLR3):c.1010G>A (p.Ser337Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001967276] Chr4:186082696 [GRCh38]
Chr4:187003850 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.287A>G (p.Gln96Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001928171] Chr4:186076906 [GRCh38]
Chr4:186998060 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2176G>A (p.Glu726Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001889315] Chr4:186083862 [GRCh38]
Chr4:187005016 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.752G>C (p.Arg251Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001894252] Chr4:186082438 [GRCh38]
Chr4:187003592 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2553C>G (p.Phe851Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001911018] Chr4:186084711 [GRCh38]
Chr4:187005865 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1571A>T (p.Asp524Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001889642] Chr4:186083257 [GRCh38]
Chr4:187004411 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2072T>C (p.Phe691Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001913010] Chr4:186083758 [GRCh38]
Chr4:187004912 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:185978583-188762387) copy number gain not specified [RCV002053476] Chr4:185978583..188762387 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:185381293-190957473) copy number loss not specified [RCV002053475] Chr4:185381293..190957473 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:186686044-190842022) copy number gain not specified [RCV002053478] Chr4:186686044..190842022 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
NM_003265.3(TLR3):c.2324C>T (p.Ser775Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001984274] Chr4:186084010 [GRCh38]
Chr4:187005164 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1498T>C (p.Ser500Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001872571] Chr4:186083184 [GRCh38]
Chr4:187004338 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1873G>A (p.Val625Ile) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001969554] Chr4:186083559 [GRCh38]
Chr4:187004713 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.256A>T (p.Thr86Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002038889] Chr4:186076875 [GRCh38]
Chr4:186998029 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1517G>A (p.Arg506His) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001876455] Chr4:186083203 [GRCh38]
Chr4:187004357 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2252_2255del (p.Thr751fs) microsatellite Herpes simplex encephalitis, susceptibility to, 1 [RCV001957627] Chr4:186083927..186083930 [GRCh38]
Chr4:187005081..187005084 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1275T>G (p.Asp425Glu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001944238] Chr4:186082961 [GRCh38]
Chr4:187004115 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2198A>G (p.Tyr733Cys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001900854] Chr4:186083884 [GRCh38]
Chr4:187005038 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1864A>G (p.Ile622Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002036985] Chr4:186083550 [GRCh38]
Chr4:187004704 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.338A>C (p.Gln113Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002033274] Chr4:186076957 [GRCh38]
Chr4:186998111 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1251T>A (p.Asn417Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001963537] Chr4:186082937 [GRCh38]
Chr4:187004091 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2687C>T (p.Ala896Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001883204] Chr4:186084845 [GRCh38]
Chr4:187005999 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.106_129del (p.Asp36_Thr43del) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV001963608] Chr4:186076723..186076746 [GRCh38]
Chr4:186997877..186997900 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1462C>T (p.Arg488Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001962810] Chr4:186083148 [GRCh38]
Chr4:187004302 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2147T>C (p.Phe716Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001989541] Chr4:186083833 [GRCh38]
Chr4:187004987 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.256A>G (p.Thr86Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002048042] Chr4:186076875 [GRCh38]
Chr4:186998029 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.38G>A (p.Gly13Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002028990] Chr4:186076657 [GRCh38]
Chr4:186997811 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2158G>T (p.Val720Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001916050] Chr4:186083844 [GRCh38]
Chr4:187004998 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.298A>T (p.Met100Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001877217] Chr4:186076917 [GRCh38]
Chr4:186998071 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.991C>T (p.Arg331Trp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001901913] Chr4:186082677 [GRCh38]
Chr4:187003831 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2530C>G (p.Leu844Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001937926] Chr4:186084688 [GRCh38]
Chr4:187005842 [GRCh37]
Chr4:4q35.1		 uncertain significance
NC_000004.11:g.(?_186064527)_(187630981_?)del deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV001877781]|not provided [RCV003120734] Chr4:186064527..187630981 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic|uncertain significance|no classifications from unflagged records
NM_003265.3(TLR3):c.535T>G (p.Ser179Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002029715] Chr4:186078933 [GRCh38]
Chr4:187000087 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2642T>C (p.Val881Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002027355] Chr4:186084800 [GRCh38]
Chr4:187005954 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.139G>A (p.Asp47Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001935682]|TLR3-related disorder [RCV003948818] Chr4:186076758 [GRCh38]
Chr4:186997912 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.140A>T (p.Asp47Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001886061]|not specified [RCV004041081] Chr4:186076759 [GRCh38]
Chr4:186997913 [GRCh37]
Chr4:4q35.1		 uncertain significance
NC_000004.11:g.(?_186423448)_(187630981_?)dup duplication not provided [RCV001982176] Chr4:186423448..187630981 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
NM_003265.3(TLR3):c.952T>A (p.Leu318Met) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002018032] Chr4:186082638 [GRCh38]
Chr4:187003792 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2487-18A>G single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001902650] Chr4:186084627 [GRCh38]
Chr4:187005781 [GRCh37]
Chr4:4q35.1		 likely benign|uncertain significance
NM_003265.3(TLR3):c.1708G>A (p.Glu570Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV001958538] Chr4:186083394 [GRCh38]
Chr4:187004548 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.369G>A (p.Thr123=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002185971] Chr4:186076988 [GRCh38]
Chr4:186998142 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.975G>A (p.Arg325=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002165172] Chr4:186082661 [GRCh38]
Chr4:187003815 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.555G>C (p.Ala185=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002170052] Chr4:186078953 [GRCh38]
Chr4:187000107 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2487-15C>T single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002147162] Chr4:186084630 [GRCh38]
Chr4:187005784 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2364G>T (p.Leu788=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002106238] Chr4:186084050 [GRCh38]
Chr4:187005204 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1714A>G (p.Asn572Asp) single nucleotide variant not provided [RCV002224678] Chr4:186083400 [GRCh38]
Chr4:187004554 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.193A>C (p.Arg65=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002129527] Chr4:186076812 [GRCh38]
Chr4:186997966 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1974T>G (p.Val658=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002071138] Chr4:186083660 [GRCh38]
Chr4:187004814 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2487-17T>C single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002111582] Chr4:186084628 [GRCh38]
Chr4:187005782 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1644C>T (p.His548=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002165037] Chr4:186083330 [GRCh38]
Chr4:187004484 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2328A>G (p.Ser776=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002215785]|TLR3-related disorder [RCV003893216] Chr4:186084014 [GRCh38]
Chr4:187005168 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1713C>T (p.Ser571=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002088878] Chr4:186083399 [GRCh38]
Chr4:187004553 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.972G>A (p.Val324=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002171495] Chr4:186082658 [GRCh38]
Chr4:187003812 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.144T>C (p.Asp48=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002086059] Chr4:186076763 [GRCh38]
Chr4:186997917 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.634-12del deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV002152669] Chr4:186082300 [GRCh38]
Chr4:187003454 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.915A>G (p.Leu305=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002205492] Chr4:186082601 [GRCh38]
Chr4:187003755 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2007T>C (p.Pro669=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002114081] Chr4:186083693 [GRCh38]
Chr4:187004847 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.174T>C (p.Leu58=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002170671] Chr4:186076793 [GRCh38]
Chr4:186997947 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.441+3A>G single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002111686]|not provided [RCV003438946] Chr4:186077063 [GRCh38]
Chr4:186998217 [GRCh37]
Chr4:4q35.1		 likely benign|uncertain significance
NM_003265.3(TLR3):c.2292T>C (p.Tyr764=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002194486] Chr4:186083978 [GRCh38]
Chr4:187005132 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2487-7dup duplication Herpes simplex encephalitis, susceptibility to, 1 [RCV002116147] Chr4:186084631..186084632 [GRCh38]
Chr4:187005785..187005786 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.2655G>T (p.Arg885=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002160670] Chr4:186084813 [GRCh38]
Chr4:187005967 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.873C>T (p.Asn291=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002161621] Chr4:186082559 [GRCh38]
Chr4:187003713 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.177C>T (p.Thr59=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002143497] Chr4:186076796 [GRCh38]
Chr4:186997950 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.765G>A (p.Leu255=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002101589] Chr4:186082451 [GRCh38]
Chr4:187003605 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2455C>T (p.His819Tyr) single nucleotide variant See cases [RCV004584473]|not provided [RCV003434451] Chr4:186084141 [GRCh38]
Chr4:187005295 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.333A>C (p.Leu111=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002217214] Chr4:186076952 [GRCh38]
Chr4:186998106 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.360C>T (p.Ala120=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002100728] Chr4:186076979 [GRCh38]
Chr4:186998133 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1552A>T (p.Ile518Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003118384] Chr4:186083238 [GRCh38]
Chr4:187004392 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1911G>A (p.Leu637=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003120002] Chr4:186083597 [GRCh38]
Chr4:187004751 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.233C>A (p.Thr78Asn) single nucleotide variant not specified [RCV004684150] Chr4:186076852 [GRCh38]
Chr4:186998006 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2668C>T (p.Arg890Cys) single nucleotide variant not specified [RCV004684149] Chr4:186084826 [GRCh38]
Chr4:187005980 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:185211271-190957473)x1 copy number loss See cases [RCV002292211] Chr4:185211271..190957473 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
GRCh37/hg19 4q34.1-35.2(chr4:174944132-190957473)x1 copy number loss FETAL DEMISE [RCV002282976] Chr4:174944132..190957473 [GRCh37]
Chr4:4q34.1-35.2		 pathogenic
GRCh37/hg19 4q32.3-35.2(chr4:167779888-190957473)x1 copy number loss See cases [RCV002292706] Chr4:167779888..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
GRCh37/hg19 4q32.1-35.2(chr4:159174483-190957473)x1 copy number loss See cases [RCV002292401] Chr4:159174483..190957473 [GRCh37]
Chr4:4q32.1-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:186473718-187912600)x3 copy number gain Craniofacial microsomia 1 [RCV002281676] Chr4:186473718..187912600 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
NM_003265.3(TLR3):c.1163A>C (p.Asn388Thr) single nucleotide variant not specified [RCV004303394] Chr4:186082849 [GRCh38]
Chr4:187004003 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:185748860-188413920)x1 copy number loss not provided [RCV002472580] Chr4:185748860..188413920 [GRCh37]
Chr4:4q35.1-35.2		 pathogenic
NM_003265.3(TLR3):c.1521C>A (p.Asn507Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002301563] Chr4:186083207 [GRCh38]
Chr4:187004361 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1408C>A (p.Gln470Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002304731] Chr4:186083094 [GRCh38]
Chr4:187004248 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1181G>T (p.Arg394Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002301857] Chr4:186082867 [GRCh38]
Chr4:187004021 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1124T>C (p.Phe375Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002299041] Chr4:186082810 [GRCh38]
Chr4:187003964 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.539A>G (p.Asn180Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002302267] Chr4:186078937 [GRCh38]
Chr4:187000091 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1987G>C (p.Glu663Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002299881] Chr4:186083673 [GRCh38]
Chr4:187004827 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1930T>C (p.Phe644Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002301858] Chr4:186083616 [GRCh38]
Chr4:187004770 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.154A>G (p.Asn52Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002970937] Chr4:186076773 [GRCh38]
Chr4:186997927 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2166C>T (p.Leu722=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002750150] Chr4:186083852 [GRCh38]
Chr4:187005006 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2095A>G (p.Ser699Gly) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003033062] Chr4:186083781 [GRCh38]
Chr4:187004935 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1737T>C (p.Val579=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002903084] Chr4:186083423 [GRCh38]
Chr4:187004577 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.968A>G (p.Asn323Ser) single nucleotide variant not specified [RCV004140620] Chr4:186082654 [GRCh38]
Chr4:187003808 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2472C>T (p.Asp824=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002967440] Chr4:186084158 [GRCh38]
Chr4:187005312 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2623T>A (p.Cys875Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603147]|not specified [RCV004239803] Chr4:186084781 [GRCh38]
Chr4:187005935 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2127T>C (p.Asn709=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003016321] Chr4:186083813 [GRCh38]
Chr4:187004967 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2432G>A (p.Arg811Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002975481] Chr4:186084118 [GRCh38]
Chr4:187005272 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2314G>A (p.Glu772Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003017265] Chr4:186084000 [GRCh38]
Chr4:187005154 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.742A>G (p.Thr248Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002756219] Chr4:186082428 [GRCh38]
Chr4:187003582 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1606G>A (p.Asp536Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002774847] Chr4:186083292 [GRCh38]
Chr4:187004446 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1177T>C (p.Leu393=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002727112] Chr4:186082863 [GRCh38]
Chr4:187004017 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1717G>A (p.Gly573Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603139]|not specified [RCV004126731] Chr4:186083403 [GRCh38]
Chr4:187004557 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.338_339del (p.Gln113fs) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV002903376] Chr4:186076957..186076958 [GRCh38]
Chr4:186998111..186998112 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.520C>G (p.Gln174Glu) single nucleotide variant not specified [RCV004106237] Chr4:186078918 [GRCh38]
Chr4:187000072 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1035G>A (p.Lys345=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003074819] Chr4:186082721 [GRCh38]
Chr4:187003875 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1787A>G (p.Asn596Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002755965] Chr4:186083473 [GRCh38]
Chr4:187004627 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2258A>T (p.Gln753Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003016607] Chr4:186083944 [GRCh38]
Chr4:187005098 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1617T>C (p.His539=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003076102] Chr4:186083303 [GRCh38]
Chr4:187004457 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.38G>C (p.Gly13Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002761639] Chr4:186076657 [GRCh38]
Chr4:186997811 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1489A>C (p.Ser497Arg) single nucleotide variant not specified [RCV004169986] Chr4:186083175 [GRCh38]
Chr4:187004329 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1997C>G (p.Thr666Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002638704] Chr4:186083683 [GRCh38]
Chr4:187004837 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2669G>C (p.Arg890Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002736589] Chr4:186084827 [GRCh38]
Chr4:187005981 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2122A>G (p.Ile708Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002760863] Chr4:186083808 [GRCh38]
Chr4:187004962 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.330G>A (p.Glu110=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003019847] Chr4:186076949 [GRCh38]
Chr4:186998103 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.13_14del (p.Leu5fs) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV002735910] Chr4:186076631..186076632 [GRCh38]
Chr4:186997785..186997786 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.442-16T>C single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003038013] Chr4:186078824 [GRCh38]
Chr4:186999978 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1025C>T (p.Ser342Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002705248] Chr4:186082711 [GRCh38]
Chr4:187003865 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1879AAG[1] (p.Lys628del) microsatellite Herpes simplex encephalitis, susceptibility to, 1 [RCV003077665] Chr4:186083563..186083565 [GRCh38]
Chr4:187004717..187004719 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1698C>T (p.Ile566=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003080809] Chr4:186083384 [GRCh38]
Chr4:187004538 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2487-8T>C single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002761169] Chr4:186084637 [GRCh38]
Chr4:187005791 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.752G>A (p.Arg251Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002824023] Chr4:186082438 [GRCh38]
Chr4:187003592 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2501A>T (p.His834Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002927158] Chr4:186084659 [GRCh38]
Chr4:187005813 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1180C>T (p.Arg394Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002913927] Chr4:186082866 [GRCh38]
Chr4:187004020 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2278A>G (p.Ile760Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002620498] Chr4:186083964 [GRCh38]
Chr4:187005118 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1950G>A (p.Thr650=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002638574] Chr4:186083636 [GRCh38]
Chr4:187004790 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2399T>C (p.Leu800Pro) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002658559] Chr4:186084085 [GRCh38]
Chr4:187005239 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2394del (p.Phe798fs) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV003085787]|Immunodeficiency 83, susceptibility to viral infections [RCV004577028] Chr4:186084076 [GRCh38]
Chr4:187005230 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.298A>G (p.Met100Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002766356] Chr4:186076917 [GRCh38]
Chr4:186998071 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2194T>C (p.Phe732Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003085924] Chr4:186083880 [GRCh38]
Chr4:187005034 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.751C>T (p.Arg251Trp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002805524] Chr4:186082437 [GRCh38]
Chr4:187003591 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.543T>C (p.Asn181=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003008114] Chr4:186078941 [GRCh38]
Chr4:187000095 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.411A>G (p.Lys137=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002917306] Chr4:186077030 [GRCh38]
Chr4:186998184 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.552A>C (p.Gln184His) single nucleotide variant not specified [RCV004147724] Chr4:186078950 [GRCh38]
Chr4:187000104 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.442-3C>T single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002711329] Chr4:186078837 [GRCh38]
Chr4:186999991 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1340T>A (p.Leu447His) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002623878] Chr4:186083026 [GRCh38]
Chr4:187004180 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2269_2270insGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGANNNNNNNNNNAAAAAAAAAAAAAAAAAAAAAGAACAGTTTGAATATG (p.Ala757fs) insertion Herpes simplex encephalitis, susceptibility to, 1 [RCV003024948] Chr4:186083938..186083939 [GRCh38]
Chr4:187005092..187005093 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1872C>T (p.Ser624=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002932178] Chr4:186083558 [GRCh38]
Chr4:187004712 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1995T>C (p.His665=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002829979] Chr4:186083681 [GRCh38]
Chr4:187004835 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.33G>C (p.Trp11Cys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003067728]|not specified [RCV004071670] Chr4:186076652 [GRCh38]
Chr4:186997806 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1947C>T (p.Cys649=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002700485] Chr4:186083633 [GRCh38]
Chr4:187004787 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1025C>A (p.Ser342Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002574047] Chr4:186082711 [GRCh38]
Chr4:187003865 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.906T>C (p.Tyr302=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003042491] Chr4:186082592 [GRCh38]
Chr4:187003746 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1977T>C (p.Asn659=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002871676] Chr4:186083663 [GRCh38]
Chr4:187004817 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.157A>G (p.Ile53Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002712149] Chr4:186076776 [GRCh38]
Chr4:186997930 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1569T>A (p.Asp523Glu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003028773] Chr4:186083255 [GRCh38]
Chr4:187004409 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1681C>T (p.Leu561=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002720028] Chr4:186083367 [GRCh38]
Chr4:187004521 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1902C>T (p.Phe634=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002811668] Chr4:186083588 [GRCh38]
Chr4:187004742 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1819A>G (p.Asn607Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003090159] Chr4:186083505 [GRCh38]
Chr4:187004659 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.848A>G (p.Tyr283Cys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002581812] Chr4:186082534 [GRCh38]
Chr4:187003688 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1747A>C (p.Lys583Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002720817] Chr4:186083433 [GRCh38]
Chr4:187004587 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1265T>C (p.Ile422Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003009942] Chr4:186082951 [GRCh38]
Chr4:187004105 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1220C>T (p.Ser407Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002600172] Chr4:186082906 [GRCh38]
Chr4:187004060 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1949C>G (p.Thr650Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003026294] Chr4:186083635 [GRCh38]
Chr4:187004789 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.938T>G (p.Leu313Trp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002806212] Chr4:186082624 [GRCh38]
Chr4:187003778 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2543T>C (p.Ile848Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003086560] Chr4:186084701 [GRCh38]
Chr4:187005855 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1501C>T (p.Pro501Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003064898] Chr4:186083187 [GRCh38]
Chr4:187004341 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.555G>A (p.Ala185=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002647882] Chr4:186078953 [GRCh38]
Chr4:187000107 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2156T>C (p.Ile719Thr) single nucleotide variant not specified [RCV004173634] Chr4:186083842 [GRCh38]
Chr4:187004996 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.965del (p.Phe322fs) deletion Herpes simplex encephalitis, susceptibility to, 1 [RCV003048652] Chr4:186082648 [GRCh38]
Chr4:187003802 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1118A>C (p.Asn373Thr) single nucleotide variant not specified [RCV004134550] Chr4:186082804 [GRCh38]
Chr4:187003958 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1561A>G (p.Ile521Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002770260] Chr4:186083247 [GRCh38]
Chr4:187004401 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1037T>C (p.Ile346Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002715185] Chr4:186082723 [GRCh38]
Chr4:187003877 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.33G>T (p.Trp11Cys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002962107] Chr4:186076652 [GRCh38]
Chr4:186997806 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1763T>A (p.Leu588Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003048596] Chr4:186083449 [GRCh38]
Chr4:187004603 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1811C>T (p.Ser604Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003051722] Chr4:186083497 [GRCh38]
Chr4:187004651 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.90T>C (p.Val30=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003068837] Chr4:186076709 [GRCh38]
Chr4:186997863 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1847A>C (p.Asn616Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003069349] Chr4:186083533 [GRCh38]
Chr4:187004687 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2090A>G (p.Lys697Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003092851] Chr4:186083776 [GRCh38]
Chr4:187004930 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2054G>A (p.Gly685Glu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003092474] Chr4:186083740 [GRCh38]
Chr4:187004894 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1691T>G (p.Leu564Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV002943809] Chr4:186083377 [GRCh38]
Chr4:187004531 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.634-18T>C single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003068628] Chr4:186082302 [GRCh38]
Chr4:187003456 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.335C>T (p.Ser112Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003052180] Chr4:186076954 [GRCh38]
Chr4:186998108 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.662G>T (p.Gly221Val) single nucleotide variant not specified [RCV004280632] Chr4:186082348 [GRCh38]
Chr4:187003502 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.493G>A (p.Gly165Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003497980]|not specified [RCV004267685] Chr4:186078891 [GRCh38]
Chr4:187000045 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.613T>A (p.Ser205Thr) single nucleotide variant not specified [RCV004274760] Chr4:186079011 [GRCh38]
Chr4:187000165 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1022C>A (p.Ala341Asp) single nucleotide variant not specified [RCV004267352] Chr4:186082708 [GRCh38]
Chr4:187003862 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1873G>T (p.Val625Phe) single nucleotide variant Immunodeficiency 83, susceptibility to viral infections [RCV003338178] Chr4:186083559 [GRCh38]
Chr4:187004713 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.89T>G (p.Val30Gly) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003873093] Chr4:186076708 [GRCh38]
Chr4:186997862 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2486+14G>A single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003881182] Chr4:186084186 [GRCh38]
Chr4:187005340 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.959G>A (p.Gly320Glu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604152] Chr4:186082645 [GRCh38]
Chr4:187003799 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q35.1-35.2(chr4:186805036-188558860)x1 copy number loss not provided [RCV003485444] Chr4:186805036..188558860 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
Single allele deletion not provided [RCV003448667] Chr4:180937545..190915069 [GRCh37]
Chr4:4q34.3-35.2		 pathogenic
GRCh37/hg19 4q35.1-35.2(chr4:186950483-187201211)x1 copy number loss not provided [RCV003485445] Chr4:186950483..187201211 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
NM_003265.3(TLR3):c.2486+50T>C single nucleotide variant not specified [RCV003488867] Chr4:186084222 [GRCh38]
Chr4:187005376 [GRCh37]
Chr4:4q35.1		 benign
NM_003265.3(TLR3):c.415A>C (p.Lys139Gln) single nucleotide variant TLR3-related disorder [RCV003418923] Chr4:186077034 [GRCh38]
Chr4:186998188 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q32.3-35.2(chr4:167409608-190957473)x3 copy number gain not provided [RCV003484595] Chr4:167409608..190957473 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
NM_003265.3(TLR3):c.2215C>A (p.His739Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003498008]|not provided [RCV003435219]|not specified [RCV004364600] Chr4:186083901 [GRCh38]
Chr4:187005055 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1645G>A (p.Ala549Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003498003]|TLR3-related disorder [RCV003410699] Chr4:186083331 [GRCh38]
Chr4:187004485 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1478A>G (p.Lys493Arg) single nucleotide variant TLR3-related disorder [RCV003410756] Chr4:186083164 [GRCh38]
Chr4:187004318 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.528T>G (p.Leu176=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603221] Chr4:186078926 [GRCh38]
Chr4:187000080 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.563G>A (p.Ser188Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603262] Chr4:186078961 [GRCh38]
Chr4:187000115 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.180T>A (p.His60Gln) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604211]|not specified [RCV004371669] Chr4:186076799 [GRCh38]
Chr4:186997953 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.898C>G (p.Leu300Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604390] Chr4:186082584 [GRCh38]
Chr4:187003738 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1555G>A (p.Ala519Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604647] Chr4:186083241 [GRCh38]
Chr4:187004395 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1159T>A (p.Ser387Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003602748] Chr4:186082845 [GRCh38]
Chr4:187003999 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.460C>T (p.Leu154=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003831635]|TLR3-related disorder [RCV003893479] Chr4:186078858 [GRCh38]
Chr4:187000012 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2268T>C (p.Tyr756=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603692] Chr4:186083954 [GRCh38]
Chr4:187005108 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2669G>A (p.Arg890His) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003605011] Chr4:186084827 [GRCh38]
Chr4:187005981 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1271G>A (p.Ser424Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603237] Chr4:186082957 [GRCh38]
Chr4:187004111 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2257C>A (p.Gln753Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603765] Chr4:186083943 [GRCh38]
Chr4:187005097 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1336G>A (p.Glu446Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003605058] Chr4:186083022 [GRCh38]
Chr4:187004176 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1044T>C (p.Asp348=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003602623] Chr4:186082730 [GRCh38]
Chr4:187003884 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.421A>G (p.Asn141Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003602709] Chr4:186077040 [GRCh38]
Chr4:186998194 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.674G>A (p.Gly225Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604643] Chr4:186082360 [GRCh38]
Chr4:187003514 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2517T>G (p.Ala839=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003877123] Chr4:186084675 [GRCh38]
Chr4:187005829 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1119T>C (p.Asn373=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604583] Chr4:186082805 [GRCh38]
Chr4:187003959 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1980G>A (p.Trp660Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604463] Chr4:186083666 [GRCh38]
Chr4:187004820 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2110C>T (p.Leu704Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003829961] Chr4:186083796 [GRCh38]
Chr4:187004950 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.441G>A (p.Lys147=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604023] Chr4:186077060 [GRCh38]
Chr4:186998214 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.632A>T (p.Glu211Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603763] Chr4:186079030 [GRCh38]
Chr4:187000184 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.753G>C (p.Arg251=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604497] Chr4:186082439 [GRCh38]
Chr4:187003593 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1991C>A (p.Thr664Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604430] Chr4:186083677 [GRCh38]
Chr4:187004831 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.32G>T (p.Trp11Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603958] Chr4:186076651 [GRCh38]
Chr4:186997805 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2498A>T (p.His833Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604584] Chr4:186084656 [GRCh38]
Chr4:187005810 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.522A>C (p.Gln174His) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604596] Chr4:186078920 [GRCh38]
Chr4:187000074 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1929C>T (p.Arg643=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604066] Chr4:186083615 [GRCh38]
Chr4:187004769 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2184G>A (p.Trp728Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604777] Chr4:186083870 [GRCh38]
Chr4:187005024 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1239C>A (p.Asn413Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003604853] Chr4:186082925 [GRCh38]
Chr4:187004079 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1923T>C (p.Asp641=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603710] Chr4:186083609 [GRCh38]
Chr4:187004763 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1318C>T (p.Leu440Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003832788] Chr4:186083004 [GRCh38]
Chr4:187004158 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1805C>T (p.Pro602Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003497586] Chr4:186083491 [GRCh38]
Chr4:187004645 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1461C>T (p.Leu487=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003497568] Chr4:186083147 [GRCh38]
Chr4:187004301 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.442-7C>G single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603402] Chr4:186078833 [GRCh38]
Chr4:186999987 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2682A>G (p.Gln894=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003498923] Chr4:186084840 [GRCh38]
Chr4:187005994 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.488A>C (p.Lys163Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499039] Chr4:186078886 [GRCh38]
Chr4:187000040 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2703C>G (p.Asn901Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003498677] Chr4:186084861 [GRCh38]
Chr4:187006015 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2608A>T (p.Met870Leu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499452] Chr4:186084766 [GRCh38]
Chr4:187005920 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1551C>T (p.Asn517=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003498740] Chr4:186083237 [GRCh38]
Chr4:187004391 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2348C>T (p.Ser783Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003603453] Chr4:186084034 [GRCh38]
Chr4:187005188 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2340A>C (p.Glu780Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003855081] Chr4:186084026 [GRCh38]
Chr4:187005180 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.847T>C (p.Tyr283His) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003810673] Chr4:186082533 [GRCh38]
Chr4:187003687 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.894A>T (p.Pro298=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003498565] Chr4:186082580 [GRCh38]
Chr4:187003734 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.813A>G (p.Leu271=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499992] Chr4:186082499 [GRCh38]
Chr4:187003653 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1925T>C (p.Met642Thr) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499256] Chr4:186083611 [GRCh38]
Chr4:187004765 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2092G>A (p.Asp698Asn) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499712] Chr4:186083778 [GRCh38]
Chr4:187004932 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2409T>C (p.Ile803=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003497545] Chr4:186084095 [GRCh38]
Chr4:187005249 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1172C>T (p.Thr391Ile) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499815] Chr4:186082858 [GRCh38]
Chr4:187004012 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.61T>C (p.Cys21Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003838030] Chr4:186076680 [GRCh38]
Chr4:186997834 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1141dup (p.Leu381fs) duplication Herpes simplex encephalitis, susceptibility to, 1 [RCV003499352] Chr4:186082825..186082826 [GRCh38]
Chr4:187003979..187003980 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1732C>T (p.Pro578Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499978] Chr4:186083418 [GRCh38]
Chr4:187004572 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1149C>T (p.Tyr383=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003497400] Chr4:186082835 [GRCh38]
Chr4:187003989 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.243T>C (p.Asp81=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003497795] Chr4:186076862 [GRCh38]
Chr4:186998016 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.526C>T (p.Leu176Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003497757] Chr4:186078924 [GRCh38]
Chr4:187000078 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1915G>A (p.Glu639Lys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003839022] Chr4:186083601 [GRCh38]
Chr4:187004755 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.441+1G>T single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003498355] Chr4:186077061 [GRCh38]
Chr4:186998215 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.789C>G (p.Thr263=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003813951] Chr4:186082475 [GRCh38]
Chr4:187003629 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.2238A>C (p.Glu746Asp) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003498830] Chr4:186083924 [GRCh38]
Chr4:187005078 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1148A>T (p.Tyr383Phe) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499255] Chr4:186082834 [GRCh38]
Chr4:187003988 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1061T>G (p.Leu354Arg) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499357] Chr4:186082747 [GRCh38]
Chr4:187003901 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1637G>A (p.Trp546Ter) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003499463] Chr4:186083323 [GRCh38]
Chr4:187004477 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1A>G (p.Met1Val) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003847047] Chr4:186076620 [GRCh38]
Chr4:186997774 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q32.1-35.2(chr4:161589441-190957473)x1 copy number loss not specified [RCV003986532] Chr4:161589441..190957473 [GRCh37]
Chr4:4q32.1-35.2		 pathogenic
NM_003265.3(TLR3):c.2204A>G (p.Asn735Ser) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003871217] Chr4:186083890 [GRCh38]
Chr4:187005044 [GRCh37]
Chr4:4q35.1		 uncertain significance
GRCh37/hg19 4q24-35.2(chr4:101203509-190957473)x3 copy number gain not specified [RCV003986496] Chr4:101203509..190957473 [GRCh37]
Chr4:4q24-35.2		 pathogenic
GRCh37/hg19 4q27-35.2(chr4:123399154-190957473)x3 copy number gain not specified [RCV003986533] Chr4:123399154..190957473 [GRCh37]
Chr4:4q27-35.2		 pathogenic
NM_003265.3(TLR3):c.1830G>A (p.Val610=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003870062] Chr4:186083516 [GRCh38]
Chr4:187004670 [GRCh37]
Chr4:4q35.1		 likely benign
NM_003265.3(TLR3):c.1261A>G (p.Lys421Glu) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003868115] Chr4:186082947 [GRCh38]
Chr4:187004101 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2180G>C (p.Gly727Ala) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003865741] Chr4:186083866 [GRCh38]
Chr4:187005020 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.395C>G (p.Ser132Cys) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003864431] Chr4:186077014 [GRCh38]
Chr4:186998168 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2661T>A (p.Gly887=) single nucleotide variant Herpes simplex encephalitis, susceptibility to, 1 [RCV003861890] Chr4:186084819 [GRCh38]
Chr4:187005973 [GRCh37]
Chr4:4q35.1		 likely benign
GRCh37/hg19 4q32.3-35.2(chr4:169060637-191154276)x1 copy number loss not provided [RCV003885510] Chr4:169060637..191154276 [GRCh37]
Chr4:4q32.3-35.2		 pathogenic
GRCh37/hg19 4p12-q35.2(chr4:45455621-191003541)x3 copy number gain not provided [RCV003885507] Chr4:45455621..191003541 [GRCh37]
Chr4:4p12-q35.2		 pathogenic
NM_003265.3(TLR3):c.1016C>G (p.Ser339Cys) single nucleotide variant not specified [RCV004470336] Chr4:186082702 [GRCh38]
Chr4:187003856 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1835T>C (p.Leu612Pro) single nucleotide variant not specified [RCV004470337] Chr4:186083521 [GRCh38]
Chr4:187004675 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.2077dup (p.Thr693fs) duplication Immunodeficiency 83, susceptibility to viral infections [RCV004577283] Chr4:186083762..186083763 [GRCh38]
Chr4:187004916..187004917 [GRCh37]
Chr4:4q35.1		 uncertain significance
NM_003265.3(TLR3):c.1942G>C (p.Asp648His) single nucleotide variant not specified [RCV004472405] Chr4:186083628 [GRCh38]
Chr4:187004782 [GRCh37]
Chr4:4q35.1		 uncertain significance
NC_000004.11:g.(?_186064502)_(187630981_?)dup duplication not provided [RCV004580822] Chr4:186064502..187630981 [GRCh37]
Chr4:4q35.1-35.2		 uncertain significance
NC_000004.11:g.(?_186997774)_(187000205_?)dup duplication Herpes simplex encephalitis, susceptibility to, 1 [RCV004580774] Chr4:186997774..187000205 [GRCh37]
Chr4:4q35.1		 uncertain significance
NC_000004.11:g.(?_186997774)_(187006027_?)dup duplication Herpes simplex encephalitis, susceptibility to, 1 [RCV004580773] Chr4:186997774..187006027 [GRCh37]
Chr4:4q35.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1107
Count of miRNA genes:690
Interacting mature miRNAs:766
Transcripts:ENST00000296795, ENST00000504367, ENST00000508051, ENST00000512264, ENST00000513189
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407249954GWAS898930_Hinterferon lambda-1 measurement QTL GWAS898930 (human)5e-13interferon lambda-1 measurement4186087860186087861Human
406949127GWAS598103_Hprotein measurement QTL GWAS598103 (human)1e-30protein measurement4186073205186073206Human
407393582GWAS1042558_Hhypothyroidism QTL GWAS1042558 (human)2e-09hypothyroidism4186082920186082921Human
407207916GWAS856892_Hprotein measurement QTL GWAS856892 (human)7e-842protein measurement4186082920186082921Human
407173918GWAS822894_Hautoimmune thyroid disease QTL GWAS822894 (human)7e-12autoimmune thyroid disease4186082920186082921Human
407364780GWAS1013756_Hresponse to ondansetron, QT interval QTL GWAS1013756 (human)0.0000002response to ondansetron, QT intervalQT interval (CMO:0000235)4186082920186082921Human
407389284GWAS1038260_Hprotein measurement QTL GWAS1038260 (human)1e-83protein measurement4186082920186082921Human
407298251GWAS947227_Hhypothyroidism QTL GWAS947227 (human)1e-13hypothyroidism4186086720186086721Human
2292972PRSTS190_HProstate tumor susceptibility QTL 190 (human)4.130.0018Prostate tumor susceptibility4175186665190214555Human
407414406GWAS1063382_HThyroid preparation use measurement QTL GWAS1063382 (human)1e-18Thyroid preparation use measurement4186080076186080077Human
407314184GWAS963160_HThyroid preparation use measurement QTL GWAS963160 (human)3e-18Thyroid preparation use measurement4186082920186082921Human
407356280GWAS1005256_Hlevel of Toll-like receptor 3 in blood serum QTL GWAS1005256 (human)1e-19level of Toll-like receptor 3 in blood serum4186082920186082921Human

Markers in Region
PMC128073P4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374186,997,885 - 186,998,152UniSTSGRCh37
Build 364187,234,879 - 187,235,146RGDNCBI36
Celera4184,320,424 - 184,320,691RGD
Cytogenetic Map4q35UniSTS
HuRef4182,750,028 - 182,750,295UniSTS
A009J16  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374187,006,007 - 187,006,175UniSTSGRCh37
Build 364187,243,001 - 187,243,169RGDNCBI36
Celera4184,328,546 - 184,328,714RGD
Cytogenetic Map4q35UniSTS
HuRef4182,758,148 - 182,758,316UniSTS
GeneMap99-GB4 RH Map4683.27UniSTS
NCBI RH Map41724.2UniSTS
D15S1477  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q32-q35UniSTS
Cytogenetic Map5q11UniSTS
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map10p12.1-p11.2UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map21q21.3UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map5q14UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map7p21.3UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map14q31-q32UniSTS
Cytogenetic Map10q25.2UniSTS
Cytogenetic Map16p13.13-p13.12UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map2p22.1UniSTS
Cytogenetic Map13q13.1UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map15q21.1UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map10q24.2UniSTS
Cytogenetic Map1q42.11UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map11q24UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map2q14UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic MapXq26.3UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map4q25UniSTS
Cytogenetic Map11q14.2UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map5q23UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map13q12.1UniSTS
Cytogenetic Map6p21.32UniSTS
Cytogenetic Map2q31UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map3p21.2UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map4q28.2UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map22q12.3UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map15q11-q13UniSTS
Cytogenetic Map19pUniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map8q11.21UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map10q23.2UniSTS
Cytogenetic Map7p22.3UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map1q31.3UniSTS
Cytogenetic Map4q35UniSTS
Cytogenetic Map9p13UniSTS
Cytogenetic Map3p24.2UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map6q25.2-q25.3UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map1q42.3UniSTS
Cytogenetic Map7q22.3UniSTS
Cytogenetic Map9q34.2UniSTS
Cytogenetic Map17q24UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map19q13.3-q13.4UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map20q13UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map17q22-q23UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map7p15.2UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map12q23.1UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map13q11UniSTS
Cytogenetic MapXp22.3UniSTS
Cytogenetic Map3p25-p24UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic MapXq22.1UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map3p12UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic MapXp11.2UniSTS
Cytogenetic Map11q13.1-q13.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map3q26.2UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map10q23.31UniSTS
Cytogenetic Map6p21.1-p12.2UniSTS
Cytogenetic Map12q14.1UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map1p35UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map8q23.1UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map14q11.1UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map19p13.3-p13.2UniSTS
Cytogenetic Map1p36.11-p34.2UniSTS
Cytogenetic Map9p22UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map9p22.1UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map11p15.1UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map3p21UniSTS
Cytogenetic Map20p11.23UniSTS
Cytogenetic Map15q15.2UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map8q12.1UniSTS
Cytogenetic Map14q21.2UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic MapXp11.22UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map18q12.3UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map12q11-q12UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map2p24UniSTS
Cytogenetic Map8q24.21UniSTS
Cytogenetic Map12q22-q23.1UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map15q21-q22UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map16p13.13UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic Map7p14-p13UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map6q22-q23UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map15q26.3UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map4q21.22UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map16p12.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map11q24.3UniSTS
Cytogenetic Map11q13.1-q13.3UniSTS
Cytogenetic Map14q24.2UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map2q24UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map10q25UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map15q21-q23UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map6p21UniSTS
Cytogenetic Map2p25.2UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map12p12.1UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map14q23.2UniSTS
Cytogenetic Map11q12UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map6p23UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map3q25.31UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map10q24.31UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map1p22.1UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map4q31.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map18q21.3UniSTS
Cytogenetic Map11q21UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map11q23.2UniSTS
Cytogenetic Map8q12UniSTS
Cytogenetic Map4q28-q32UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map12q24.11UniSTS
Cytogenetic Map9q21.12UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map20p11.22-p11.1UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map2q24.3UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map9q31-q33UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map10p11.23UniSTS
Cytogenetic Map6q15UniSTS
Cytogenetic Map5q35.2UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map3q26.1-q26.2UniSTS
Cytogenetic Map5q11.2-q13.2UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic MapXq13.3UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map5q35.1UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map4q21.21UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic MapXq21.1UniSTS
Cytogenetic Map10p11.21UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map5q34UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map16q23.2UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map15q24UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map12q21UniSTS
Cytogenetic Map8p11.2UniSTS
Cytogenetic Map7q22-q31UniSTS
Cytogenetic Map22q12UniSTS
Cytogenetic Map4q22UniSTS
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map12q14UniSTS
Cytogenetic Map11q23.1-q23.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map17qUniSTS
Cytogenetic Map2q33UniSTS
Cytogenetic Map7qUniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map13q22.1UniSTS
Cytogenetic Map3p25.2UniSTS
Cytogenetic Map5q21.3UniSTS
Cytogenetic Map9q22.2UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic Map6p24.2UniSTS
D8S2279  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map21q22.12UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map15q22.3UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map21q21.3UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map17q24.2UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map12q24.1UniSTS
Cytogenetic Map7p15.2UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map2p25.2UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map5q14UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map7q21.11UniSTS
Cytogenetic Map9q34.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map6p21.1-p12UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map7p21.3UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map22q11.22UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map1q12UniSTS
Cytogenetic Map8p23UniSTS
Cytogenetic Map11q13.2-q13.3UniSTS
Cytogenetic Map13q14.1-q14.3UniSTS
Cytogenetic Map3q22-q24UniSTS
Cytogenetic Map3q13.1-q13.2UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map5q23.3-q31.1UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7q32UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map17q11UniSTS
Cytogenetic Map17p13.1-p12UniSTS
Cytogenetic Map18q21.33UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map1q21-q23UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map17p12-p11.2UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map2q32UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map2q33UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map3q27UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map10q23-q24UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map14q31-q32UniSTS
Cytogenetic Map5p15.33UniSTS
Cytogenetic Map1q23.2UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map2q32.3UniSTS
Cytogenetic Map15q21.1UniSTS
Cytogenetic Map4q32.2UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map5q14.2UniSTS
Cytogenetic Map4q32.1UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map11q14.1UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map6q22UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map22q12.3UniSTS
Cytogenetic Map20q11UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map18p11.31UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map2p22.1UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map1p35.2UniSTS
Cytogenetic MapYp11.2UniSTS
Cytogenetic Map13q13.1UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map18q12UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map3q27.2UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map5p15.2UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map1q42UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map17q21.2-q21.3UniSTS
Cytogenetic Map5q32-q34UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map16q13UniSTS
Cytogenetic Map3q21.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map14q24.2UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map10p12UniSTS
Cytogenetic Map2q33.3UniSTS
Cytogenetic Map14q21.3UniSTS
Cytogenetic Map8p22-p21UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map12q21.33UniSTS
Cytogenetic Map20q13.32UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map7q31.1UniSTS
Cytogenetic Map1p33UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map3q25UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map14q31.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map22q13.31-q13.33UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map7q32.2UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map14q31-q32.1UniSTS
Cytogenetic Map1q42.11UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map2q11.2-q12.1UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map2q14UniSTS
Cytogenetic Map20p11.23-p11.21UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map8p11.23UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic MapXq26.3UniSTS
Cytogenetic Map8q24.11UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map9q22.33UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map9q21.32UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map20q12UniSTS
Cytogenetic Map4q21.23UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map2q21.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map12q24.11UniSTS
Cytogenetic Map18q21UniSTS
Cytogenetic Map10q11.1UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map7q34-q35UniSTS
Cytogenetic Map15q24.1UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map6p25.1-p23UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map18q12.1-q21.1UniSTS
Cytogenetic Map12p13.1UniSTS
Cytogenetic Map13q12.1UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map6p21.32UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map12p13.1-p12.3UniSTS
Cytogenetic Map3p25.2UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map3p21.2UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic MapXp21.2UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map9q21.12UniSTS
Cytogenetic Map15q23UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map7q33UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map4q21.22UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map10q24.31UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map2q24.3UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map3q13.31UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map6q25UniSTS
Cytogenetic Map6p21UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map12p13-p12UniSTS
Cytogenetic Map9p13.2UniSTS
Cytogenetic Map6p22UniSTS
Cytogenetic Map2q12.1UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map9q22.2UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map1p22.1UniSTS
Cytogenetic Map1p36UniSTS
Cytogenetic Map9q13-q21UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic MapXp11.2UniSTS
Cytogenetic Map19pUniSTS
Cytogenetic Map19p13.1-p12UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map12q24.33U