KDR (kinase insert domain receptor) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: KDR (kinase insert domain receptor) Homo sapiens
Analyze
Symbol: KDR
Name: kinase insert domain receptor
RGD ID: 731018
HGNC Page HGNC
Description: Enables several functions, including cell adhesion molecule binding activity; vascular endothelial growth factor binding activity; and vascular endothelial growth factor-activated receptor activity. Involved in several processes, including intracellular signal transduction; positive regulation of endothelial cell migration; and protein phosphorylation. Acts upstream of or within several processes, including branching involved in blood vessel morphogenesis; positive regulation of mitochondrial depolarization; and positive regulation of mitochondrial fission. Located in several cellular components, including Golgi apparatus; endosome; and membrane raft. Is integral component of plasma membrane. Implicated in several diseases, including artery disease (multiple); gastrointestinal system cancer (multiple); glioblastoma; macular degeneration (multiple); and pancreatic cancer (multiple). Biomarker of several diseases, including breast cancer (multiple); carcinoma (multiple); cerebrovascular disease (multiple); eye disease (multiple); and systemic scleroderma (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD309; fetal liver kinase 1; fetal liver kinase-1; FLK1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor; vascular endothelial growth factor receptor 2; VEGFR; VEGFR2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl455,078,481 - 55,125,595 (-)EnsemblGRCh38hg38GRCh38
GRCh38455,078,481 - 55,125,595 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37455,944,648 - 55,991,762 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36455,639,406 - 55,686,519 (-)NCBINCBI36hg18NCBI36
Build 34455,785,576 - 55,832,690NCBI
Celera453,446,341 - 53,493,673 (-)NCBI
Cytogenetic Map4q12NCBI
HuRef451,893,013 - 51,940,346 (-)NCBIHuRef
CHM1_1455,979,683 - 56,027,015 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Lung Injury  (ISO)
adenocarcinoma  (EXP)
adhesions of uterus  (IEP,ISO)
allergic contact dermatitis  (IEP)
amyotrophic lateral sclerosis  (IEP)
angiosarcoma  (EXP)
Animal Mammary Neoplasms  (ISO)
arteriosclerosis  (IEP,ISO)
arteriovenous malformations of the brain  (IEP)
asthma  (IEP,ISO)
atherosclerosis  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
breast cancer  (IEP)
breast carcinoma  (IEP)
Breast Neoplasms  (EXP,ISO)
cerebral cavernous malformation  (IEP)
Cerebral Hemorrhage  (EXP)
Choroidal Neovascularization  (IDA,ISO)
chronic obstructive pulmonary disease  (IEP)
colitis  (ISO)
colon carcinoma  (IAGP,ISO)
Colonic Neoplasms  (ISO)
colorectal adenocarcinoma  (IDA,IMP)
colorectal cancer  (IAGP)
Colorectal Neoplasms  (EXP)
contact dermatitis  (ISO)
corneal neovascularization  (ISO)
Coronary Disease  (IEP)
Crohn's disease  (IEP)
cystitis  (ISO)
decubitus ulcer  (IEP)
Diabetic Nephropathies  (EXP)
diffuse scleroderma  (IEP)
Endometrial Neoplasms  (IEP)
Endometrioid Carcinomas  (IEP)
endometriosis  (ISO)
Esophageal Neoplasms  (EXP)
esophagus adenocarcinoma  (IAGP)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Neoplasms  (EXP)
glioblastoma  (IMP)
Hand-Foot Syndrome  (IAGP)
hepatocellular carcinoma  (IAGP,IEP)
herpes simplex virus keratitis  (ISO)
high grade glioma  (IEP,ISO)
High Myopia  (IAGP)
Hirschsprung Disease 1  (IAGP)
hydrophthalmos  (ISO)
hypertension  (IAGP,ISO)
Hypoxia-Ischemia, Brain  (ISO)
impotence  (ISO)
Infantile Capillary Hemangioma  (IAGP)
inverted papilloma  (IEP)
Kidney Neoplasms  (ISO)
Kuhnt-Junius degeneration  (IAGP)
Lathyrism  (ISO)
limited scleroderma  (IEP)
liver cirrhosis  (IEP)
lung carcinoma  (ISO)
lung non-small cell carcinoma  (IAGP,IEP,ISO)
lymphangioma  (IEP)
Lymphatic Metastasis  (ISO)
macular degeneration  (IAGP,ISO)
macular retinal edema  (IEP)
Mammary Neoplasms, Experimental  (IMP,ISO)
melanoma  (IEP,ISO)
myocardial infarction  (IDA,ISO)
Myocardial Ischemia  (EXP)
Nasal Polyps  (IEP)
nasopharynx carcinoma  (IEP)
Neoplasm Metastasis  (IEP)
Neovascularization, Pathologic  (EXP)
Neuralgia  (ISO)
neurilemmoma  (IEP)
neurofibrosarcoma  (ISO)
osteochondrodysplasia  (EXP)
Otitis Media with Effusion  (ISO)
ovarian hyperstimulation syndrome  (ISO)
Ovarian Neoplasms  (IEP)
Oxygen-Induced Retinopathy  (ISO)
pancreatic cancer  (EXP,IDA)
pancreatic carcinoma  (IMP)
primary ovarian insufficiency  (IAGP)
prostate adenocarcinoma  (IEP,ISO)
prostate cancer  (IAGP)
prostatic hypertrophy  (ISO)
psoriasis  (IEP,ISO)
pterygium  (IEP)
renal cell carcinoma  (ISO)
Reperfusion Injury  (EXP,ISO)
retinal telangiectasia  (IEP)
retinopathy of prematurity  (IEP,ISO)
salivary gland carcinoma  (IEP)
sarcoma  (IEP)
schizophrenia  (EXP)
Seasonal Allergic Rhinitis  (IEP)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
stomach cancer  (IAGP)
Stroke  (ISO)
systemic scleroderma  (IEP)
temporal lobe epilepsy  (EXP)
tongue squamous cell carcinoma  (ISO)
transitional cell carcinoma  (IEP)
Transplant Rejection  (ISO)
type 2 diabetes mellitus  (IEP)
ulcerative colitis  (IEP)
uremia  (EXP)
urinary bladder cancer  (IEP,IMP)
Uterine Cervical Neoplasms  (IEP)
uveal melanoma  (IEP)
Venous Thrombosis  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3'-diindolylmethane  (EXP)
3,5,6-trichloro-2-pyridinol  (ISO)
3,5,6-trichloropyridine-2-one  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
afimoxifene  (EXP)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
amiodarone  (ISO)
andrographolide  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
aspartame  (EXP)
belinostat  (EXP)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzylpenicillin  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP)
bisphenol F  (ISO)
bortezomib  (EXP)
cadmium atom  (EXP)
calcidiol  (ISO)
calcitriol  (ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
coumarin  (EXP)
crocidolite asbestos  (EXP)
curcumin  (EXP,ISO)
Curcumol  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cypermethrin  (ISO)
D-glucose  (EXP,ISO)
Deguelin  (EXP)
demethoxycurcumin  (EXP)
diarsenic trioxide  (EXP)
diethylstilbestrol  (ISO)
dioscin  (EXP)
dioxygen  (EXP,ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
embelin  (EXP)
enalapril  (ISO)
Enterolactone  (ISO)
entinostat  (EXP,ISO)
ethanol  (ISO)
ethyl trans-caffeate  (EXP)
flutamide  (ISO)
folic acid  (ISO)
fructose  (ISO)
fumonisin B1  (ISO)
furosemide  (ISO)
gefitinib  (ISO)
genistein  (ISO)
geraniol  (ISO)
glafenine  (ISO)
glucose  (EXP,ISO)
glycidol  (ISO)
glyphosate  (EXP)
hexachlorobenzene  (EXP)
indoles  (ISO)
isoprenaline  (ISO)
L-ascorbic acid  (EXP)
L-ethionine  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lithium chloride  (ISO)
losartan  (ISO)
medroxyprogesterone acetate  (EXP)
melittin  (EXP)
methoxychlor  (ISO)
methyl caffeate  (EXP)
methylisothiazolinone  (EXP)
methylmercury chloride  (EXP)
mifepristone  (ISO)
monocrotaline  (ISO)
monosodium L-glutamate  (ISO)
N-acetyl-L-cysteine  (EXP)
N-acetylsphingosine  (EXP,ISO)
N-ethyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
nicotinic acid  (ISO)
O-methyleugenol  (EXP)
omeprazole  (ISO)
orantinib  (EXP)
orlistat  (EXP)
oxaliplatin  (ISO)
ozone  (ISO)
p-menthan-3-ol  (EXP)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
PCB138  (ISO)
PD123319  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenylephrine  (ISO)
phenytoin  (ISO)
phosgene  (ISO)
pirinixic acid  (ISO)
platycodin D  (EXP)
ponatinib  (EXP)
Ponicidin  (EXP)
potassium dichromate  (ISO)
progesterone  (EXP,ISO)
quercetin  (EXP)
quercitrin  (EXP)
quinazolines  (EXP)
resveratrol  (EXP)
riddelliine  (ISO)
rosuvastatin calcium  (ISO)
rotenone  (ISO)
saccharin  (ISO)
sarpogrelate  (ISO)
SB 431542  (EXP)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP)
sorafenib  (EXP)
sphingosine 1-phosphate  (EXP)
streptozocin  (ISO)
sunitinib  (EXP)
superoxide  (EXP)
tanespimycin  (EXP,ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thalidomide  (EXP)
thioacetamide  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
triclosan  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
undecane  (ISO)
urea  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
valsartan  (EXP,ISO)
vinclozolin  (ISO)
vorinostat  (EXP)
WIN 55212-2  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
angiogenesis  (TAS)
branching involved in blood vessel morphogenesis  (IMP)
branching morphogenesis of an epithelial tube  (ISO)
calcium ion homeostasis  (ISO)
calcium-mediated signaling using intracellular calcium source  (IMP)
cell fate commitment  (ISO)
cell maturation  (ISO)
cell migration  (IBA,ISO)
cell migration involved in sprouting angiogenesis  (ISS)
cellular response to hydrogen sulfide  (IDA)
cellular response to vascular endothelial growth factor stimulus  (IDA,IMP)
embryonic hemopoiesis  (ISS)
endocardium development  (ISO)
endochondral bone growth  (ISO)
endothelial cell differentiation  (IBA,ISO)
endothelial tube morphogenesis  (ISO)
endothelium development  (ISS)
ERK1 and ERK2 cascade  (IMP)
hematopoietic progenitor cell differentiation  (IBA)
hemopoiesis  (ISO)
lung alveolus development  (ISO)
lung development  (ISO)
lymph vessel development  (ISO)
male gonad development  (ISO)
negative regulation of apoptotic process  (IMP)
negative regulation of endothelial cell apoptotic process  (IDA)
negative regulation of gene expression  (IDA)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of systemic arterial blood pressure  (ISO)
neuron projection morphogenesis  (ISO)
ovarian follicle development  (ISO)
peptidyl-tyrosine autophosphorylation  (ISS)
peptidyl-tyrosine phosphorylation  (IDA)
positive regulation of angiogenesis  (IBA,IMP,ISO)
positive regulation of blood vessel endothelial cell migration  (IMP)
positive regulation of BMP signaling pathway  (ISO)
positive regulation of calcium-mediated signaling  (ISO)
positive regulation of cell migration  (IDA,IMP,ISO)
positive regulation of cell migration involved in sprouting angiogenesis  (IMP)
positive regulation of cell population proliferation  (IDA,IMP,ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway  (IDA)
positive regulation of endothelial cell migration  (IMP)
positive regulation of endothelial cell proliferation  (IMP,ISO)
positive regulation of epithelial cell proliferation  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IMP)
positive regulation of focal adhesion assembly  (IDA)
positive regulation of kinase activity  (IBA)
positive regulation of long-term neuronal synaptic plasticity  (ISO)
positive regulation of macroautophagy  (IGI)
positive regulation of MAPK cascade  (IDA)
positive regulation of mesenchymal cell proliferation  (ISO)
positive regulation of mitochondrial depolarization  (IGI)
positive regulation of mitochondrial fission  (IGI)
positive regulation of neurogenesis  (ISO)
positive regulation of nitric-oxide synthase biosynthetic process  (IDA,IMP)
positive regulation of phosphatidylinositol 3-kinase signaling  (IDA,ISO)
positive regulation of positive chemotaxis  (IDA)
positive regulation of protein phosphorylation  (IDA)
positive regulation of TOR signaling  (ISO)
positive regulation of vasculogenesis  (ISS)
post-embryonic camera-type eye morphogenesis  (ISO)
protein autophosphorylation  (IDA,ISO)
protein kinase B signaling  (IMP)
regulation of bone development  (ISO)
regulation of cell shape  (IDA)
regulation of hematopoietic progenitor cell differentiation  (ISO)
response to hypoxia  (ISO)
response to oxygen levels  (ISO)
response to xenobiotic stimulus  (ISO)
surfactant homeostasis  (ISO)
transmembrane receptor protein tyrosine kinase signaling pathway  (IBA)
vascular endothelial growth factor receptor signaling pathway  (IDA,IMP,ISO,TAS)
vascular endothelial growth factor receptor-2 signaling pathway  (IMP)
vascular endothelial growth factor signaling pathway  (IMP)
vascular wound healing  (IMP)
vasculogenesis  (ISO,ISS)
vasodilation  (ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
1. Angelov L, etal., Cancer Res. 1999 Nov 1;59(21):5536-41.
2. Arita S, etal., Int J Gynecol Cancer. 2005 Mar-Apr;15(2):329-36.
3. Aucejo F, etal., Liver Transpl. 2009 Feb;15(2):169-76. doi: 10.1002/lt.21678.
4. Azizi Y, etal., Eur J Pharmacol. 2015 Aug 15;761:101-8. doi: 10.1016/j.ejphar.2015.04.034. Epub 2015 May 1.
5. Badalian G, etal., Anticancer Res. 2007 Mar-Apr;27(2):889-94.
6. Bai AS, etal., Zhonghua Nan Ke Xue. 2007 Apr;13(4):324-6.
7. Brennan M, etal., Eur J Clin Pharmacol. 2012 May;68(5):645-55. Epub 2011 Dec 15.
8. Brockington A, etal., J Neuropathol Exp Neurol. 2006 Jan;65(1):26-36.
9. Brown LF, etal., J Immunol. 1995 Mar 15;154(6):2801-7.
10. Bruno S, etal., Cytokine. 2006 Apr;34(1-2):56-65. Epub 2006 May 15.
11. Butkiewicz D, etal., Int J Cancer. 2015 Nov 15;137(10):2332-42. doi: 10.1002/ijc.29605. Epub 2015 Jun 3.
12. Carrai V, etal., Rheumatology (Oxford). 2012 Jun;51(6):1042-8. doi: 10.1093/rheumatology/ker447. Epub 2012 Jan 23.
13. Carroll RS, etal., Cancer. 1999 Oct 1;86(7):1335-41.
14. Chae SS, etal., Clin Cancer Res. 2010 Jul 15;16(14):3618-27. Epub 2010 May 25.
15. Chae SW, etal., Acta Otolaryngol. 2003 Jun;123(5):559-63.
16. Chen JX, etal., Braz J Med Biol Res. 2019 Oct 7;52(10):e8324. doi: 10.1590/1414-431X20198324. eCollection 2019.
17. Choi JS, etal., J Histochem Cytochem. 2007 Aug;55(8):821-30. Epub 2007 Apr 4.
18. Choi JS, etal., J Neurotrauma. 2007 Mar;24(3):521-31.
19. Conrad C, etal., Anticancer Drugs. 2007 Jun;18(5):569-79. doi: 10.1097/CAD.0b013e3280147d13.
20. Davidoff AM, etal., Cancer Res. 2002 Jun 1;62(11):3077-83.
21. De Young L, etal., J Sex Med. 2005 Mar;2(2):199-206.
22. Di H, etal., Zhonghua Fu Chan Ke Za Zhi. 2000 Nov;35(11):670-2.
23. Ding M, etal., Chin J Cancer Res. 2014 Dec;26(6):669-77. doi: 10.3978/j.issn.1000-9604.2014.12.04.
24. Dong G, etal., Cancer Sci. 2012 Mar;103(3):561-8. doi: 10.1111/j.1349-7006.2011.02194.x. Epub 2012 Jan 16.
25. Fadini GP, etal., Stroke. 2006 Sep;37(9):2277-82. Epub 2006 Jul 27.
26. Feng Y, etal., Neuroscience. 2011 Apr 14;179:223-32. Epub 2011 Jan 28.
27. Foster KA, etal., Neurosci Res. 2009 Jan;63(1):10-6. Epub 2008 Oct 4.
28. Gakiopoulou-Givalou H, etal., Histopathology. 2003 Sep;43(3):272-9.
29. Gebhardt M, etal., Ophthalmology. 2005 Jun;112(6):1023-30.
30. Giatromanolaki A, etal., Cancer. 2001 Nov 15;92(10):2569-77.
31. Giatromanolaki A, etal., Clin Exp Metastasis. 2012 Jan;29(1):11-7. doi: 10.1007/s10585-011-9424-6. Epub 2011 Oct 9.
32. Giatromanolaki A, etal., Mod Pathol. 2006 May;19(5):701-7.
33. GOA_HUMAN data from the GO Consortium
34. Gumus K, etal., Br J Ophthalmol. 2013 Feb 1.
35. Han FJ, etal., Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2000 Feb;14(2):65-7.
36. Haymerle G, etal., Eur Arch Otorhinolaryngol. 2016 Sep;273(9):2717-26. doi: 10.1007/s00405-015-3805-4. Epub 2015 Oct 23.
37. Heffelfinger SC, etal., Lab Invest. 2004 Aug;84(8):989-98.
38. Henno A, etal., J Dermatol Sci. 2010 Mar;57(3):162-9. doi: 10.1016/j.jdermsci.2009.12.006. Epub 2010 Jan 7.
39. Hermann MM, etal., Ophthalmology. 2013 Dec 20. pii: S0161-6420(13)01056-7. doi: 10.1016/j.ophtha.2013.10.047.
40. Higashi-Kuwata N, etal., Eur J Dermatol. 2011 Jul-Aug;21(4):490-4. doi: 10.1684/ejd.2011.1284.
41. Holmes K, etal., Cell Signal. 2007 Oct;19(10):2003-12. Epub 2007 Jun 12.
42. Huang H, etal., PLoS One. 2011;6(6):e21411. Epub 2011 Jun 22.
43. Ibrahim A, etal., Nutrition. 2012 Jul;28(7-8):799-802. doi: 10.1016/j.nut.2011.10.008. Epub 2012 Jan 20.
44. Inan S, etal., Histol Histopathol. 2006 Oct;21(10):1055-64.
45. Jain L, etal., J Exp Clin Cancer Res. 2010 Jul 14;29:95. doi: 10.1186/1756-9966-29-95.
46. Jantus-Lewintre E, etal., Lung Cancer. 2011 Nov;74(2):326-31. doi: 10.1016/j.lungcan.2011.02.016. Epub 2011 Apr 9.
47. Jesmin S, etal., Exp Biol Med (Maywood). 2006 Jun;231(6):902-6.
48. Jesmin S, etal., Inflammation. 2011 Apr 29.
49. Jesmin S, etal., J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S160-4.
50. Jinnin M, etal., Br J Dermatol. 2010 Apr;162(4):751-8. doi: 10.1111/j.1365-2133.2009.09567.x. Epub 2009 Nov 3.
51. Karashima T, etal., Int J Oncol. 2007 Apr;30(4):937-45.
52. Kase S, etal., Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):57-62. doi: 10.1167/iovs.12-10613.
53. Keskin U, etal., Ophthalmic Res. 2012;47(1):13-8. doi: 10.1159/000324994. Epub 2011 Jun 21.
54. Kim B, etal., J Immunol. 2006 Sep 15;177(6):4122-31.
55. Kim BW, etal., Cell Signal. 2008 Apr;20(4):714-25. Epub 2007 Dec 17.
56. Kim DG, etal., MAbs. 2015;7(6):1195-204. doi: 10.1080/19420862.2015.1086854. Epub 2015 Sep 1.
57. Kim YS, etal., J Immunol. 2010 Nov 1;185(9):5648-55. Epub 2010 Oct 4.
58. Kinose F, etal., Mol Vis. 2005 May 27;11:366-73.
59. Kivela R, etal., FASEB J. 2006 Jul;20(9):1570-2.
60. Kranenburg AR, etal., Thorax. 2005 Feb;60(2):106-13.
61. Kranz A, etal., Int J Cancer. 1999 Jun 21;84(3):293-8.
62. Krishnan ST, etal., Diabetes Care. 2007 Dec;30(12):3058-62. Epub 2007 Sep 26.
63. Kusama-Eguchi K, etal., J Comp Neurol. 2010 Mar 15;518(6):928-42.
64. Lazzeri S, etal., ScientificWorldJournal. 2012;2012:420190. doi: 10.1100/2012/420190. Epub 2012 Aug 1.
65. Lee C and Agoston DV, Exp Neurol. 2009 Dec;220(2):400-3. Epub 2009 Sep 3.
66. Lin J, etal., Brain Res Bull. 2010 Oct 30;83(5):284-91. Epub 2010 Aug 10.
67. Lin YF, etal., Pol J Pathol. 2014 Oct;65(3):194-201. doi: 10.5114/pjp.2014.45781.
68. Liu L, etal., Urol Int. 2008;81(1):72-6. Epub 2008 Jul 16.
69. Liu X, etal., Zhonghua Er Ke Za Zhi. 2007 Jan;45(1):7-13.
70. Liu YF, etal., Int J Mol Sci. 2015 Jan 12;16(1):1576-89. doi: 10.3390/ijms16011576.
71. Machado DE, etal., Fertil Steril. 2010 May 15;93(8):2674-9. Epub 2010 Jan 13.
72. Machado MV, etal., Eur J Gastroenterol Hepatol. 2014 Apr;26(4):438-43. doi: 10.1097/MEG.0000000000000044.
73. McColl BK, etal., APMIS 2004 Jul-Aug;112(7-8):463-80.
74. Meng QW, etal., Zhonghua Yi Xue Za Zhi. 2013 Jan 29;93(5):341-4.
75. Meunier-Carpentier S, etal., Int J Oncol. 2005 Apr;26(4):977-84.
76. Miller DW, etal., Am J Pathol. 2005 Nov;167(5):1389-403.
77. Miyazawa M, etal., Cancer Sci. 2010 Feb;101(2):433-9. Epub 2009 Oct 27.
78. Mochimaru H, etal., Invest Ophthalmol Vis Sci. 2008 May;49(5):2172-7. doi: 10.1167/iovs.07-1396. Epub 2008 Feb 8.
79. Nagai R, etal., Adv Exp Med Biol 2003;538:57-65; discussion 66.
80. Nakopoulou L, etal., Hum Pathol. 2002 Sep;33(9):863-70.
81. Niethammer AG, etal., Nat Med. 2002 Dec;8(12):1369-75. doi: 10.1038/nm1202-794. Epub 2002 Nov 4.
82. Noma H, etal., JAMA Ophthalmol. 2013 Feb;131(2):160-5. doi: 10.1001/2013.jamaophthalmol.228.
83. Norgall S, etal., BMC Cancer. 2007 Jun 21;7:105.
84. Nykanen AI, etal., Transplantation. 2005 Jan 27;79(2):182-9.
85. Olsson AK, etal., Nat Rev Mol Cell Biol. 2006 May;7(5):359-71.
86. OMIM Disease Annotation Pipeline
87. Petrovan RJ, etal., Arterioscler Thromb Vasc Biol. 2007 May;27(5):1095-100. Epub 2007 Feb 15.
88. Pieh C, etal., Br J Ophthalmol. 2008 May;92(5):689-93. doi: 10.1136/bjo.2007.128371. Epub 2008 Apr 11.
89. Pipeline to import KEGG annotations from KEGG into RGD
90. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
91. Pipeline to import SMPDB annotations from SMPDB into RGD
92. Pisacane AM and Risio M, Melanoma Res. 2005 Feb;15(1):39-43.
93. Pufe T, etal., J Pathol. 2003 May;200(1):130-6.
94. Ran S, etal., Neoplasia. 2003 Jul-Aug;5(4):297-307.
95. Ratnasari N, etal., Kobe J Med Sci. 2015 Dec 18;61(3):E89-96.
96. Renno RZ, etal., Arch Ophthalmol. 2004 Jul;122(7):1002-11.
97. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
98. RGD automated import pipeline for gene-chemical interactions
99. RGD automated import pipeline for human HPO-to-gene-to-disease annotations
100. Roland CL, etal., PLoS One. 2009 Nov 3;4(11):e7669.
101. Roscoe WA, etal., J Neuroimmunol. 2009 Apr 30;209(1-2):6-15. Epub 2009 Feb 23.
102. Sano D, etal., Arch Otolaryngol Head Neck Surg. 2009 Apr;135(4):411-20. doi: 10.1001/archoto.2009.14.
103. Sano K, etal., Biochem Biophys Res Commun. 2012 Apr 6;420(2):422-7. doi: 10.1016/j.bbrc.2012.03.011. Epub 2012 Mar 9.
104. Sasso FC, etal., J Am Coll Cardiol. 2005 Sep 6;46(5):827-34.
105. Scaldaferri F, etal., Gastroenterology. 2009 Feb;136(2):585-95.e5. Epub 2008 Oct 7.
106. Schmid-Brunclik N, etal., Am J Physiol Regul Integr Comp Physiol. 2008 Sep;295(3):R864-73. Epub 2008 Jul 9.
107. Scotti L, etal., J Steroid Biochem Mol Biol. 2014 Oct;144 Pt B:392-401. doi: 10.1016/j.jsbmb.2014.08.013. Epub 2014 Aug 23.
108. Seto T, etal., Lung Cancer. 2006 Jul;53(1):91-6. doi: 10.1016/j.lungcan.2006.02.009. Epub 2006 May 11.
109. Sha D and He YJ, Ai Zheng. 2006 Feb;25(2):229-34.
110. Shao JC, etal., Zhonghua Nan Ke Xue. 2005 Jun;11(6):413-8.
111. Shimotake J, etal., Stroke. 2010 Feb;41(2):343-9.
112. Skold MK, etal., J Neurotrauma. 2005 Mar;22(3):353-67.
113. Soler R, etal., Neurourol Urodyn. 2011 Mar;30(3):428-34. doi: 10.1002/nau.21002. Epub 2010 Oct 29.
114. Takahashi H, etal., Curr Eye Res. 2008 Nov;33(11):1002-10. doi: 10.1080/02713680802492440.
115. Takahashi H, etal., Invest Ophthalmol Vis Sci. 2008 May;49(5):2143-7. doi: 10.1167/iovs.07-0523.
116. Takeda A, etal., Graefes Arch Clin Exp Ophthalmol. 2003 Sep;241(9):765-72. Epub 2003 Aug 23.
117. Tardy I, etal., Invest Radiol. 2010 Oct;45(10):573-8.
118. Uehara H, etal., FASEB J. 2013 Jan;27(1):76-85. doi: 10.1096/fj.12-213835. Epub 2012 Sep 20.
119. Uesaka T, etal., J Neurooncol. 2007 Jul;83(3):259-66. Epub 2007 Feb 14.
120. Uranishi R, etal., Neurosurgery. 2001 Feb;48(2):359-67; discussion 367-8.
121. Vihinen PP, etal., Melanoma Res. 2011 Oct;21(5):431-7. doi: 10.1097/CMR.0b013e32834941d3.
122. Waldner MJ, etal., J Exp Med. 2010 Dec 20;207(13):2855-68. Epub 2010 Nov 22.
123. Wang H, etal., Zhonghua Bing Li Xue Za Zhi. 2002 Oct;31(5):391-5.
124. Watanabe H, etal., Exp Dermatol. 2004 Nov;13(11):671-81.
125. Wilkinson-Berka JL, etal., Am J Pathol. 2004 Apr;164(4):1263-73.
126. Wu H, etal., Neurosurgery. 2011 May;68(5):1363-71; discussion 1371.
127. Wu IC, etal., Neoplasia. 2011 Apr;13(4):386-92. doi: 10.1593/neo.101722.
128. Xia G, etal., J Urol. 2006 Apr;175(4):1245-52.
129. Yan HX, etal., Mol Med Rep. 2013 Aug;8(2):434-8. doi: 10.3892/mmr.2013.1500. Epub 2013 May 31.
130. Yang F, etal., Cancer Res. 2011 Aug 15;71(16):5512-21. doi: 10.1158/0008-5472.CAN-10-2614. Epub 2011 Jul 1.
131. Yang J, etal., Chin Med J (Engl). 2002 Aug;115(8):1251-2.
132. Yazawa H, etal., Cancer Gene Ther. 2006 Nov;13(11):993-1001. doi: 10.1038/sj.cgt.7700970. Epub 2006 Jun 9.
133. Yockman JW, etal., Gene Ther. 2007 Oct;14(19):1399-405. Epub 2007 Jul 26.
134. Yuksel H, etal., Clin Exp Allergy. 2007 Aug;37(8):1183-8.
135. Zhang X, etal., Curr Eye Res. 2012 Jan;37(1):73-9. Epub 2011 Nov 28.
136. Zhang Z, etal., Chin Med J (Engl). 2002 Aug;115(8):1209-12.
137. Zheng YB, etal., Med Oncol. 2014 Oct;31(10):209. doi: 10.1007/s12032-014-0209-z. Epub 2014 Sep 3.
138. Zhu X, etal., Cancer Biol Ther. 2019;20(4):497-504. doi: 10.1080/15384047.2018.1537575. Epub 2018 Oct 31.
139. Zhuang PY, etal., Oncotarget. 2014 Nov 30;5(22):11121-32. doi: 10.18632/oncotarget.2553.
140. Zuo SG, etal., Biol Pharm Bull. 2010;33(2):174-82. doi: 10.1248/bpb.33.174.
Additional References at PubMed
PMID:1417831   PMID:1656371   PMID:1717995   PMID:7559454   PMID:7736781   PMID:7929439   PMID:7999104   PMID:8126087   PMID:8621427   PMID:8889548   PMID:8946838   PMID:9256359  
PMID:9398617   PMID:9405464   PMID:9435229   PMID:9621077   PMID:9790910   PMID:9804796   PMID:9837777   PMID:9973224   PMID:10022831   PMID:10037737   PMID:10102632   PMID:10319320  
PMID:10329451   PMID:10368301   PMID:10428027   PMID:10455194   PMID:10579917   PMID:10590123   PMID:10600473   PMID:10608891   PMID:10692392   PMID:10749680   PMID:10865839   PMID:10873597  
PMID:10961983   PMID:11145723   PMID:11166270   PMID:11332691   PMID:11333271   PMID:11387210   PMID:11409852   PMID:11494124   PMID:11688957   PMID:11693202   PMID:11807987   PMID:11809684  
PMID:11824379   PMID:11852061   PMID:11886873   PMID:11908876   PMID:11948691   PMID:11950700   PMID:11960378   PMID:11986954   PMID:11994280   PMID:12023952   PMID:12029087   PMID:12067897  
PMID:12114318   PMID:12154000   PMID:12174363   PMID:12213878   PMID:12214271   PMID:12426207   PMID:12439912   PMID:12456025   PMID:12464608   PMID:12477932   PMID:12509223   PMID:12529448  
PMID:12551914   PMID:12560084   PMID:12598525   PMID:12607599   PMID:12649282   PMID:12652295   PMID:12670961   PMID:12716911   PMID:12796773   PMID:12810080   PMID:12810700   PMID:12820653  
PMID:12887919   PMID:12920240   PMID:12949011   PMID:14532277   PMID:14600159   PMID:14602571   PMID:14635716   PMID:14654077   PMID:14674128   PMID:14687619   PMID:14691147   PMID:14704231  
PMID:14724572   PMID:14726393   PMID:14760936   PMID:14764537   PMID:14967383   PMID:14977921   PMID:14996703   PMID:15016828   PMID:15026417   PMID:15051508   PMID:15060076   PMID:15082792  
PMID:15111490   PMID:15135240   PMID:15135259   PMID:15166498   PMID:15175347   PMID:15183893   PMID:15215251   PMID:15217908   PMID:15247219   PMID:15284224   PMID:15291808   PMID:15342556  
PMID:15470196   PMID:15474514   PMID:15492987   PMID:15500293   PMID:15507525   PMID:15522955   PMID:15528360   PMID:15542434   PMID:15610528   PMID:15625130   PMID:15637071   PMID:15638384  
PMID:15673613   PMID:15693894   PMID:15806151   PMID:15845615   PMID:15857508   PMID:15941713   PMID:15962004   PMID:15962006   PMID:15975559   PMID:15980434   PMID:15985432   PMID:16007196  
PMID:16049137   PMID:16105658   PMID:16169405   PMID:16226108   PMID:16260429   PMID:16308314   PMID:16322069   PMID:16339483   PMID:16361360   PMID:16375118   PMID:16423422   PMID:16439688  
PMID:16453023   PMID:16467880   PMID:16513643   PMID:16516857   PMID:16530705   PMID:16574784   PMID:16617095   PMID:16630933   PMID:16648151   PMID:16678129   PMID:16682007   PMID:16684957  
PMID:16697675   PMID:16761623   PMID:16763549   PMID:16782059   PMID:16786116   PMID:16787925   PMID:16807673   PMID:16835467   PMID:16870555   PMID:16893970   PMID:16901919   PMID:16909199  
PMID:16914140   PMID:16914267   PMID:16930552   PMID:16951193   PMID:16966330   PMID:17013089   PMID:17018613   PMID:17088944   PMID:17222790   PMID:17242158   PMID:17293873   PMID:17318185  
PMID:17336974   PMID:17372230   PMID:17456229   PMID:17462601   PMID:17470361   PMID:17490619   PMID:17575273   PMID:17577783   PMID:17599955   PMID:17631646   PMID:17640715   PMID:17641225  
PMID:17646929   PMID:17702744   PMID:17707181   PMID:17721629   PMID:17722983   PMID:17765237   PMID:17850794   PMID:17868650   PMID:17881084   PMID:17891484   PMID:17927494   PMID:17928406  
PMID:17961532   PMID:17979890   PMID:17999592   PMID:18006432   PMID:18035072   PMID:18037047   PMID:18162457   PMID:18164591   PMID:18175243   PMID:18194650   PMID:18211808   PMID:18218912  
PMID:18223683   PMID:18261985   PMID:18317954   PMID:18325345   PMID:18337563   PMID:18356031   PMID:18377662   PMID:18379357   PMID:18396391   PMID:18421240   PMID:18443354   PMID:18509004  
PMID:18564921   PMID:18593464   PMID:18594014   PMID:18609713   PMID:18628209   PMID:18651620   PMID:18656381   PMID:18662404   PMID:18692535   PMID:18719373   PMID:18784964   PMID:18785001  
PMID:18818406   PMID:18824714   PMID:18840653   PMID:18922344   PMID:18931684   PMID:18936167   PMID:18975312   PMID:18977327   PMID:18987662   PMID:18996102   PMID:18997771   PMID:19014781  
PMID:19020728   PMID:19021062   PMID:19023980   PMID:19033661   PMID:19050761   PMID:19058181   PMID:19066962   PMID:19068081   PMID:19082506   PMID:19110567   PMID:19136612   PMID:19141860  
PMID:19160077   PMID:19176370   PMID:19179362   PMID:19199116   PMID:19200976   PMID:19218116   PMID:19244479   PMID:19246491   PMID:19261502   PMID:19265684   PMID:19267251   PMID:19287991  
PMID:19324448   PMID:19372376   PMID:19372461   PMID:19372622   PMID:19375500   PMID:19409555   PMID:19419943   PMID:19435508   PMID:19453261   PMID:19469899   PMID:19520980   PMID:19521715  
PMID:19558547   PMID:19563658   PMID:19570985   PMID:19595210   PMID:19605404   PMID:19633424   PMID:19636022   PMID:19665480   PMID:19695569   PMID:19701853   PMID:19706677   PMID:19706681  
PMID:19707156   PMID:19726758   PMID:19741061   PMID:19773544   PMID:19776290   PMID:19779861   PMID:19782046   PMID:19811263   PMID:19818105   PMID:19834490   PMID:19837659   PMID:19837976  
PMID:19850021   PMID:19857463   PMID:19860625   PMID:19862822   PMID:19875757   PMID:19881969   PMID:19884766   PMID:19888537   PMID:19902430   PMID:19913121   PMID:19924384   PMID:19936766  
PMID:19953880   PMID:19965681   PMID:20008289   PMID:20011623   PMID:20019880   PMID:20026801   PMID:20032607   PMID:20048182   PMID:20080685   PMID:20084021   PMID:20084057   PMID:20103598  
PMID:20103629   PMID:20124452   PMID:20135347   PMID:20143086   PMID:20145116   PMID:20158393   PMID:20158395   PMID:20164029   PMID:20167365   PMID:20170163   PMID:20179233   PMID:20182906  
PMID:20190562   PMID:20195243   PMID:20215856   PMID:20218294   PMID:20222950   PMID:20224550   PMID:20236940   PMID:20301658   PMID:20360595   PMID:20367641   PMID:20388479   PMID:20389299  
PMID:20395257   PMID:20446891   PMID:20453000   PMID:20463083   PMID:20471686   PMID:20473929   PMID:20484670   PMID:20485168   PMID:20501673   PMID:20510958   PMID:20529868   PMID:20538805  
PMID:20548028   PMID:20602615   PMID:20606037   PMID:20615131   PMID:20628086   PMID:20635108   PMID:20660291   PMID:20674013   PMID:20686603   PMID:20695190   PMID:20706192   PMID:20716285  
PMID:20800603   PMID:20824203   PMID:20842453   PMID:20851763   PMID:20854187   PMID:20923780   PMID:20959405   PMID:20963665   PMID:21041381   PMID:21047416   PMID:21048041   PMID:21062896  
PMID:21063020   PMID:21084743   PMID:21129272   PMID:21130043   PMID:21131553   PMID:21159176   PMID:21163065   PMID:21165437   PMID:21168388   PMID:21173732   PMID:21177802   PMID:21190990  
PMID:21191630   PMID:21208252   PMID:21208810   PMID:21219538   PMID:21220477   PMID:21257617   PMID:21303671   PMID:21343372   PMID:21382095   PMID:21382277   PMID:21388971   PMID:21389833  
PMID:21396771   PMID:21402774   PMID:21409488   PMID:21412269   PMID:21424032   PMID:21445972   PMID:21478036   PMID:21498704   PMID:21524919   PMID:21539813   PMID:21544626   PMID:21586748  
PMID:21590454   PMID:21596751   PMID:21599511   PMID:21605611   PMID:21612582   PMID:21635552   PMID:21636804   PMID:21653826   PMID:21658307   PMID:21659473   PMID:21667138   PMID:21671140  
PMID:21680174   PMID:21683519   PMID:21692879   PMID:21694464   PMID:21705026   PMID:21712447   PMID:21715322   PMID:21751212   PMID:21808992   PMID:21826315   PMID:21827221   PMID:21849059  
PMID:21858086   PMID:21864059   PMID:21867402   PMID:21873635   PMID:21882181   PMID:21885851   PMID:21893193   PMID:21900206   PMID:21909756   PMID:21937609   PMID:21980525   PMID:21985798  
PMID:22002459   PMID:22003972   PMID:22016416   PMID:22019447   PMID:22020326   PMID:22025615   PMID:22038228   PMID:22062947   PMID:22095559   PMID:22095860   PMID:22099303   PMID:22129133  
PMID:22153185   PMID:22159994   PMID:22169262   PMID:22170730   PMID:22174934   PMID:22184869   PMID:22199315   PMID:22203927   PMID:22203933   PMID:22207738   PMID:22208996   PMID:22227235  
PMID:22229497   PMID:22268049   PMID:22274884   PMID:22301682   PMID:22303475   PMID:22314185   PMID:22327338   PMID:22344734   PMID:22362758   PMID:22386962   PMID:22393126   PMID:22395975  
PMID:22404826   PMID:22407444   PMID:22426130   PMID:22473693   PMID:22499991   PMID:22507619   PMID:22510937   PMID:22520092   PMID:22528855   PMID:22539090   PMID:22541078   PMID:22541785  
PMID:22542663   PMID:22553146   PMID:22587628   PMID:22592917   PMID:22654102   PMID:22659165   PMID:22689825   PMID:22690749   PMID:22706170   PMID:22707264   PMID:22710795   PMID:22711876  
PMID:22718841   PMID:22723445   PMID:22730813   PMID:22763125   PMID:22772062   PMID:22789536   PMID:22828632   PMID:22897854   PMID:22955733   PMID:22956423   PMID:22965144   PMID:22975327  
PMID:23030506   PMID:23038639   PMID:23059888   PMID:23060442   PMID:23077562   PMID:23111153   PMID:23139789   PMID:23146028   PMID:23151382   PMID:23155052   PMID:23158831   PMID:23169005  
PMID:23171577   PMID:23172303   PMID:23174599   PMID:23187125   PMID:23202541   PMID:23250775   PMID:23254951   PMID:23258273   PMID:23262137   PMID:23273598   PMID:23293110   PMID:23331867  
PMID:23341459   PMID:23348691   PMID:23363445   PMID:23370473   PMID:23374253   PMID:23376830   PMID:23392734   PMID:23393131   PMID:23393387   PMID:23397142   PMID:23400753   PMID:23402259  
PMID:23418605   PMID:23424651   PMID:23454747   PMID:23475388   PMID:23511629   PMID:23516476   PMID:23529610   PMID:23533349   PMID:23536763   PMID:23548264   PMID:23551429   PMID:23555666  
PMID:23583373   PMID:23583911   PMID:23609797   PMID:23620752   PMID:23624620   PMID:23635398   PMID:23636508   PMID:23684887   PMID:23685409   PMID:23688497   PMID:23697367   PMID:23708980  
PMID:23709605   PMID:23723256   PMID:23746980   PMID:23749886   PMID:23754286   PMID:23759331   PMID:23771478   PMID:23772669   PMID:23792958   PMID:23794399   PMID:23798385   PMID:23799140  
PMID:23805312   PMID:23831629   PMID:23861747   PMID:23898208   PMID:23934537   PMID:23940030   PMID:23971975   PMID:23972086   PMID:23979202   PMID:23990986   PMID:24120473   PMID:24123039  
PMID:24170768   PMID:24184958   PMID:24205206   PMID:24260556   PMID:24296159   PMID:24300896   PMID:24303885   PMID:24335081   PMID:24341227   PMID:24385342   PMID:24409324   PMID:24442426  
PMID:24508097   PMID:24521356   PMID:24522370   PMID:24529377   PMID:24568071   PMID:24585635   PMID:24620033   PMID:24633336   PMID:24641672   PMID:24652518   PMID:24667918   PMID:24675699  
PMID:24686084   PMID:24687381   PMID:24713547   PMID:24738074   PMID:24845798   PMID:24863063   PMID:24880751   PMID:24886133   PMID:24903995   PMID:24952635   PMID:24952732   PMID:24982127  
PMID:25025175   PMID:25111127   PMID:25111568   PMID:25114179   PMID:25123269   PMID:25128562   PMID:25128838   PMID:25147336   PMID:25182240   PMID:25187647   PMID:25192841   PMID:25217645  
PMID:25217984   PMID:25245329   PMID:25261665   PMID:25269419   PMID:25293577   PMID:25322777   PMID:25329517   PMID:25331892   PMID:25340839   PMID:25353068   PMID:25354586   PMID:25378411  
PMID:25387128   PMID:25399804   PMID:25411163   PMID:25441661   PMID:25471788   PMID:25488616   PMID:25501707   PMID:25521357   PMID:25521758   PMID:25550804   PMID:25560472   PMID:25569182  
PMID:25644401   PMID:25657827   PMID:25682871   PMID:25698653   PMID:25707392   PMID:25713439   PMID:25738571   PMID:25754303   PMID:25756047   PMID:25775978   PMID:25787923   PMID:25810250  
PMID:25825981   PMID:25872462   PMID:25878330   PMID:25883000   PMID:25893857   PMID:25895461   PMID:25896473   PMID:25909285   PMID:25948043   PMID:25967108   PMID:25970161   PMID:25971967  
PMID:25976977   PMID:25978354   PMID:25979342   PMID:25986862   PMID:26014518   PMID:26021484   PMID:26021863   PMID:26028346   PMID:26037503   PMID:26059764   PMID:26080815   PMID:26081139  
PMID:26093379   PMID:26126033   PMID:26137585   PMID:26169036   PMID:26174951   PMID:26191229   PMID:26199386   PMID:26211596   PMID:26254223   PMID:26259755   PMID:26268996   PMID:26298629  
PMID:26307753   PMID:26337470   PMID:26345385   PMID:26375674   PMID:26420897   PMID:26459253   PMID:26476544   PMID:26496610   PMID:26510548   PMID:26541778   PMID:26577922   PMID:26600200  
PMID:26600539   PMID:26619847   PMID:26627848   PMID:26631613   PMID:26653034   PMID:26655705   PMID:26671532   PMID:26709129   PMID:26726843   PMID:26735859   PMID:26783205   PMID:26853422  
PMID:26866667   PMID:26879375   PMID:26881237   PMID:26890264   PMID:26902100   PMID:26909862   PMID:26934556   PMID:26935904   PMID:26940611   PMID:26967562   PMID:26981634   PMID:26993523  
PMID:27044328   PMID:27052314   PMID:27052508   PMID:27059553   PMID:27075652   PMID:27075925   PMID:27143427   PMID:27151212   PMID:27163696   PMID:27163716   PMID:27165081   PMID:27175642  
PMID:27178307   PMID:27221921   PMID:27248821   PMID:27298320   PMID:27365461   PMID:27401249   PMID:27420801   PMID:27426958   PMID:27438146   PMID:27438154   PMID:27453397   PMID:27461391  
PMID:27484635   PMID:27517319   PMID:27569654   PMID:27589831   PMID:27590851   PMID:27626484   PMID:27645229   PMID:27656109   PMID:27713170   PMID:27756875   PMID:27789775   PMID:27833959  
PMID:27834687   PMID:27836223   PMID:27836681   PMID:27837630   PMID:27846250   PMID:27872190   PMID:27922668   PMID:27930691   PMID:27989785   PMID:27999191   PMID:28011500   PMID:28026128  
PMID:28040437   PMID:28065597   PMID:28069703   PMID:28088809   PMID:28122380   PMID:28159803   PMID:28178265   PMID:28183800   PMID:28193911   PMID:28203682   PMID:28218664   PMID:28220020  
PMID:28271280   PMID:28275303   PMID:28283889   PMID:28303365   PMID:28315681   PMID:28339363   PMID:28358369   PMID:28401369   PMID:28410224   PMID:28424170   PMID:28467484   PMID:28478454  
PMID:28489720   PMID:28537244   PMID:28601637   PMID:28609170   PMID:28621236   PMID:28627623   PMID:28637396   PMID:28665417   PMID:28680264   PMID:28687357   PMID:28718364   PMID:28783175  
PMID:28812437   PMID:28847506   PMID:28854900   PMID:28865413   PMID:28927665   PMID:28948378   PMID:28991928   PMID:29039561   PMID:29051140   PMID:29058688   PMID:29203232   PMID:29226875  
PMID:29351188   PMID:29391273   PMID:29401587   PMID:29401597   PMID:29402992   PMID:29436685   PMID:29444818   PMID:29446853   PMID:29450744   PMID:29454091   PMID:29497919   PMID:29588308  
PMID:29608400   PMID:29630862   PMID:29734754   PMID:29743977   PMID:29777301   PMID:29787601   PMID:29845300   PMID:29904943   PMID:29925934   PMID:29984822   PMID:30021884   PMID:30027561  
PMID:30036530   PMID:30066848   PMID:30086460   PMID:30096614   PMID:30120232   PMID:30132564   PMID:30133118   PMID:30139844   PMID:30232381   PMID:30236477   PMID:30256387   PMID:30279732  
PMID:30289073   PMID:30396316   PMID:30401688   PMID:30417360   PMID:30423986   PMID:30456868   PMID:30475086   PMID:30483760   PMID:30540496   PMID:30589500   PMID:30615171   PMID:30700502  
PMID:30719715   PMID:30724452   PMID:30775874   PMID:30779868   PMID:30845284   PMID:30858542   PMID:30873824   PMID:30910851   PMID:30918240   PMID:30929546   PMID:30956148   PMID:30991288  
PMID:31023337   PMID:31096819   PMID:31115562   PMID:31169331   PMID:31236742   PMID:31240525   PMID:31307975   PMID:31340156   PMID:31363885   PMID:31370204   PMID:31376092   PMID:31381906  
PMID:31405022   PMID:31429823   PMID:31432097   PMID:31477752   PMID:31486713   PMID:31492751   PMID:31545422   PMID:31562188   PMID:31564130   PMID:31604823   PMID:31604908   PMID:31625068  
PMID:31717420   PMID:31755336   PMID:31876763   PMID:31896485   PMID:31922962   PMID:31932617   PMID:31980491   PMID:32019488   PMID:32074519   PMID:32088190   PMID:32123305   PMID:32169399  
PMID:32274611   PMID:32348765   PMID:32392440   PMID:32517158   PMID:32616654   PMID:32636303   PMID:32645858   PMID:32706142   PMID:32908134   PMID:32993587   PMID:32997825   PMID:33035615  
PMID:33051419   PMID:33099473   PMID:33223512   PMID:33274003   PMID:33405003   PMID:33466887  


Genomics

Comparative Map Data
KDR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl455,078,481 - 55,125,595 (-)EnsemblGRCh38hg38GRCh38
GRCh38455,078,481 - 55,125,595 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37455,944,648 - 55,991,762 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36455,639,406 - 55,686,519 (-)NCBINCBI36hg18NCBI36
Build 34455,785,576 - 55,832,690NCBI
Celera453,446,341 - 53,493,673 (-)NCBI
Cytogenetic Map4q12NCBI
HuRef451,893,013 - 51,940,346 (-)NCBIHuRef
CHM1_1455,979,683 - 56,027,015 (-)NCBICHM1_1
Kdr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39576,093,487 - 76,139,885 (-)NCBIGRCm39mm39
GRCm39 Ensembl576,093,487 - 76,139,118 (-)Ensembl
GRCm38575,932,827 - 75,979,072 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl575,932,827 - 75,978,458 (-)EnsemblGRCm38mm10GRCm38
MGSCv37576,329,290 - 76,374,453 (-)NCBIGRCm37mm9NCBIm37
MGSCv36576,214,962 - 76,260,125 (-)NCBImm8
Celera573,218,468 - 73,263,674 (-)NCBICelera
Cytogenetic Map5C3.3NCBI
cM Map540.23NCBI
Kdr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21432,217,871 - 32,261,018 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1432,217,871 - 32,261,018 (+)Ensembl
Rnor_6.01434,727,677 - 34,787,127 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1434,727,623 - 34,787,183 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01434,557,361 - 34,618,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1431,512,534 - 31,554,989 (+)NCBICelera
Cytogenetic Map14p11NCBI
Kdr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544715,810,815 - 15,853,583 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544715,810,816 - 15,851,702 (+)NCBIChiLan1.0ChiLan1.0
KDR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1475,377,847 - 75,424,927 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl475,377,375 - 75,427,109 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0468,813,894 - 68,861,018 (+)NCBIMhudiblu_PPA_v0panPan3
KDR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11347,442,861 - 47,484,574 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1347,442,764 - 47,485,042 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1347,400,610 - 47,442,293 (-)NCBI
ROS_Cfam_1.01348,053,730 - 48,095,387 (-)NCBI
UMICH_Zoey_3.11347,729,487 - 47,771,112 (-)NCBI
UNSW_CanFamBas_1.01347,258,117 - 47,299,735 (-)NCBI
UU_Cfam_GSD_1.01348,206,381 - 48,248,022 (-)NCBI
Kdr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528528,716,920 - 28,760,830 (+)NCBI
SpeTri2.0NW_00493648217,537,697 - 17,581,320 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KDR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl841,809,116 - 41,856,339 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1841,809,116 - 41,856,379 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2843,919,330 - 43,966,984 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KDR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1713,435,059 - 13,482,236 (+)NCBI
ChlSab1.1 Ensembl713,435,096 - 13,482,771 (+)Ensembl
Vero_WHO_p1.0NW_02366606614,207,326 - 14,254,753 (+)NCBI
Kdr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476114,330,224 - 14,380,680 (+)NCBI

Position Markers
RH70435  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,973,881 - 55,974,055UniSTSGRCh37
Build 36455,668,638 - 55,668,812RGDNCBI36
Celera453,475,795 - 53,475,969RGD
Cytogenetic Map4q11-q12UniSTS
HuRef451,922,466 - 51,922,640UniSTS
GeneMap99-GB4 RH Map4333.98UniSTS
NCBI RH Map4579.4UniSTS
GDB:626090  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,970,871 - 55,971,086UniSTSGRCh37
Build 36455,665,628 - 55,665,843RGDNCBI36
Celera453,472,785 - 53,473,000RGD
Cytogenetic Map4q11-q12UniSTS
HuRef451,919,456 - 51,919,671UniSTS
GDB:626093  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,945,968 - 55,946,110UniSTSGRCh37
Build 36455,640,725 - 55,640,867RGDNCBI36
Celera453,447,883 - 53,448,025RGD
Cytogenetic Map4q11-q12UniSTS
HuRef451,894,555 - 51,894,697UniSTS
KDR  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,946,175 - 55,946,251UniSTSGRCh37
GRCh37455,955,082 - 55,955,574UniSTSGRCh37
Build 36455,640,932 - 55,641,008RGDNCBI36
Celera453,456,997 - 53,457,489UniSTS
Celera453,448,090 - 53,448,166RGD
HuRef451,894,762 - 51,894,838UniSTS
HuRef451,903,669 - 51,904,161UniSTS
SHGC-50925  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,945,993 - 55,946,083UniSTSGRCh37
Build 36455,640,750 - 55,640,840RGDNCBI36
Celera453,447,908 - 53,447,998RGD
Cytogenetic Map4q11-q12UniSTS
HuRef451,894,580 - 51,894,670UniSTS
SHGC-59525  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,946,150 - 55,946,296UniSTSGRCh37
Build 36455,640,907 - 55,641,053RGDNCBI36
Celera453,448,065 - 53,448,211RGD
Cytogenetic Map4q11-q12UniSTS
HuRef451,894,737 - 51,894,883UniSTS
GeneMap99-GB4 RH Map4329.6UniSTS
NCBI RH Map4580.8UniSTS
G20520  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,944,821 - 55,945,026UniSTSGRCh37
Build 36455,639,578 - 55,639,783RGDNCBI36
Celera453,446,736 - 53,446,941RGD
Cytogenetic Map4q11-q12UniSTS
HuRef451,893,408 - 51,893,613UniSTS
A005U41  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,944,821 - 55,945,026UniSTSGRCh37
Build 36455,639,578 - 55,639,783RGDNCBI36
Celera453,446,736 - 53,446,941RGD
Cytogenetic Map4q11-q12UniSTS
HuRef451,893,408 - 51,893,613UniSTS
GeneMap99-GB4 RH Map4316.26UniSTS
NCBI RH Map4580.8UniSTS
SHGC-59221  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q11-q12UniSTS
GeneMap99-GB4 RH Map4335.57UniSTS
Whitehead-RH Map4417.1UniSTS
NCBI RH Map4680.6UniSTS
KDR  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37455,946,175 - 55,946,251UniSTSGRCh37
GRCh37455,955,082 - 55,955,574UniSTSGRCh37
Build 36455,640,932 - 55,641,008RGDNCBI36
Celera453,456,997 - 53,457,489UniSTS
Celera453,448,090 - 53,448,166RGD
HuRef451,894,762 - 51,894,838UniSTS
HuRef451,903,669 - 51,904,161UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR424hsa-miR-424-5pMirecordsexternal_info{changed}NA21885851
MIR200Bhsa-miR-200b-3pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI21544626

Predicted Target Of
Summary Value
Count of predictions:1226
Count of miRNA genes:603
Interacting mature miRNAs:671
Transcripts:ENST00000263923, ENST00000509309, ENST00000512566
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1342 1320 1280 206 212 154 2582 1015 940 274 721 1347 55 1 1202 1529 4
Low 978 926 410 392 369 281 1747 1132 2734 102 665 109 112 2 1259 2
Below cutoff 18 697 18 13 763 15 20 28 40 11 26 56 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_012004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC021220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC111194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF035121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF063658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC131822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM978033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP280621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU826563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ899739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP761779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP761780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP761781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP761782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP761783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP761784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP774600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP774601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP774602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT253192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT585185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L04947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X61656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X89776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000263923   ⟹   ENSP00000263923
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl455,078,481 - 55,125,595 (-)Ensembl
RefSeq Acc Id: ENST00000509309
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl455,094,850 - 55,096,720 (-)Ensembl
RefSeq Acc Id: ENST00000512566
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl455,104,593 - 55,125,293 (-)Ensembl
RefSeq Acc Id: ENST00000647068
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl455,078,531 - 55,122,921 (-)Ensembl
RefSeq Acc Id: NM_002253   ⟹   NP_002244
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38455,078,481 - 55,125,595 (-)NCBI
GRCh37455,944,426 - 55,991,762 (-)ENTREZGENE
Build 36455,639,406 - 55,686,519 (-)NCBI Archive
HuRef451,893,013 - 51,940,346 (-)ENTREZGENE
CHM1_1455,979,683 - 56,027,015 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_002244 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA59459 (Get FASTA)   NCBI Sequence Viewer  
  AAB88005 (Get FASTA)   NCBI Sequence Viewer  
  AAC16450 (Get FASTA)   NCBI Sequence Viewer  
  AAI31823 (Get FASTA)   NCBI Sequence Viewer  
  ACF47599 (Get FASTA)   NCBI Sequence Viewer  
  ACR78514 (Get FASTA)   NCBI Sequence Viewer  
  AKN45942 (Get FASTA)   NCBI Sequence Viewer  
  AKN45943 (Get FASTA)   NCBI Sequence Viewer  
  AKN45944 (Get FASTA)   NCBI Sequence Viewer  
  AKN45945 (Get FASTA)   NCBI Sequence Viewer  
  AKN45946 (Get FASTA)   NCBI Sequence Viewer  
  AKN45947 (Get FASTA)   NCBI Sequence Viewer  
  AKN45948 (Get FASTA)   NCBI Sequence Viewer  
  AKN45949 (Get FASTA)   NCBI Sequence Viewer  
  AKN45950 (Get FASTA)   NCBI Sequence Viewer  
  ALS54733 (Get FASTA)   NCBI Sequence Viewer  
  ALS54734 (Get FASTA)   NCBI Sequence Viewer  
  ALS54735 (Get FASTA)   NCBI Sequence Viewer  
  ALS54736 (Get FASTA)   NCBI Sequence Viewer  
  ALS54737 (Get FASTA)   NCBI Sequence Viewer  
  ALS54738 (Get FASTA)   NCBI Sequence Viewer  
  ALS54739 (Get FASTA)   NCBI Sequence Viewer  
  ALS54740 (Get FASTA)   NCBI Sequence Viewer  
  ALS54741 (Get FASTA)   NCBI Sequence Viewer  
  BAD93138 (Get FASTA)   NCBI Sequence Viewer  
  BAG57114 (Get FASTA)   NCBI Sequence Viewer  
  CAA43837 (Get FASTA)   NCBI Sequence Viewer  
  CAA61916 (Get FASTA)   NCBI Sequence Viewer  
  EAX05462 (Get FASTA)   NCBI Sequence Viewer  
  EAX05463 (Get FASTA)   NCBI Sequence Viewer  
  EAX05464 (Get FASTA)   NCBI Sequence Viewer  
  P35968 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_002244   ⟸   NM_002253
- Peptide Label: precursor
- UniProtKB: P35968 (UniProtKB/Swiss-Prot),   A0A024RD88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000263923   ⟸   ENST00000263923
Protein Domains
Ig-like C2-type   Pkinase_Tyr   Protein kinase

Promoters
RGD ID:6867474
Promoter ID:EPDNEW_H6902
Type:initiation region
Name:KDR_1
Description:kinase insert domain receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38455,125,595 - 55,125,655EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_002253.3(KDR):c.3439C>T (p.Pro1147Ser) single nucleotide variant Hemangioma, capillary infantile [RCV000013110]|not specified [RCV000121300] Chr4:55088939 [GRCh38]
Chr4:55955106 [GRCh37]
Chr4:4q12		 pathogenic|other|not provided
NM_002253.3(KDR):c.1444T>C (p.Cys482Arg) single nucleotide variant Hemangioma, capillary infantile [RCV000013111]|not provided [RCV001355593]|not specified [RCV000121295] Chr4:55106779 [GRCh38]
Chr4:55972946 [GRCh37]
Chr4:4q12		 risk factor|likely benign|not provided
GRCh38/hg38 4q12(chr4:51870025-55102392)x1 copy number loss See cases [RCV000050988] Chr4:51870025..55102392 [GRCh38]
Chr4:52736191..55968559 [GRCh37]
Chr4:52430948..55663316 [NCBI36]
Chr4:4q12		 pathogenic
GRCh38/hg38 4p13-q13.1(chr4:44356201-62245882)x3 copy number gain See cases [RCV000050683] Chr4:44356201..62245882 [GRCh38]
Chr4:44358218..63111600 [GRCh37]
Chr4:44052975..62794195 [NCBI36]
Chr4:4p13-q13.1		 pathogenic
GRCh38/hg38 4q12-13.2(chr4:51831622-66991489)x3 copy number gain See cases [RCV000051771] Chr4:51831622..66991489 [GRCh38]
Chr4:52697788..67857207 [GRCh37]
Chr4:52392545..67539802 [NCBI36]
Chr4:4q12-13.2		 pathogenic
GRCh38/hg38 4q12-22.3(chr4:51831622-97505618)x3 copy number gain See cases [RCV000051772] Chr4:51831622..97505618 [GRCh38]
Chr4:52697788..98426769 [GRCh37]
Chr4:52392545..98645792 [NCBI36]
Chr4:4q12-22.3		 pathogenic
GRCh38/hg38 4q12-13.1(chr4:51899860-59984479)x3 copy number gain See cases [RCV000051773] Chr4:51899860..59984479 [GRCh38]
Chr4:52766026..60850197 [GRCh37]
Chr4:52460783..60532792 [NCBI36]
Chr4:4q12-13.1		 pathogenic
GRCh38/hg38 4q12-13.1(chr4:52639018-59984479)x1 copy number loss See cases [RCV000053265] Chr4:52639018..59984479 [GRCh38]
Chr4:53505185..60850197 [GRCh37]
Chr4:53199942..60532792 [NCBI36]
Chr4:4q12-13.1		 pathogenic
GRCh38/hg38 4q12-13.1(chr4:54198601-62270115)x1 copy number loss See cases [RCV000053266] Chr4:54198601..62270115 [GRCh38]
Chr4:55064768..63135833 [GRCh37]
Chr4:54759525..62818428 [NCBI36]
Chr4:4q12-13.1		 pathogenic
NM_002253.2(KDR):c.3357G>A (p.Leu1119=) single nucleotide variant Malignant melanoma [RCV000066459] Chr4:55089421 [GRCh38]
Chr4:55955588 [GRCh37]
Chr4:55650345 [NCBI36]
Chr4:4q12		 not provided
NM_002253.2(KDR):c.3728C>T (p.Pro1243Leu) single nucleotide variant Malignant melanoma [RCV000061012] Chr4:55082570 [GRCh38]
Chr4:55948737 [GRCh37]
Chr4:55643494 [NCBI36]
Chr4:4q12		 not provided
NM_002253.2(KDR):c.1338G>A (p.Thr446=) single nucleotide variant Malignant melanoma [RCV000061013] Chr4:55107811 [GRCh38]
Chr4:55973978 [GRCh37]
Chr4:55668735 [NCBI36]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.1384T>G (p.Leu462Val) single nucleotide variant not provided [RCV000861138]|not specified [RCV000121292] Chr4:55107765 [GRCh38]
Chr4:55973932 [GRCh37]
Chr4:4q12		 benign|not provided
NM_002253.3(KDR):c.1416A>T (p.Gln472His) single nucleotide variant not specified [RCV000121293] Chr4:55106807 [GRCh38]
Chr4:55972974 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.1493A>T (p.Glu498Val) single nucleotide variant not specified [RCV000121294] Chr4:55106730 [GRCh38]
Chr4:55972897 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.1615G>A (p.Gly539Arg) single nucleotide variant not provided [RCV000862412]|not specified [RCV000121296] Chr4:55105862 [GRCh38]
Chr4:55972029 [GRCh37]
Chr4:4q12		 likely benign|not provided
NM_002253.3(KDR):c.2066C>T (p.Thr689Met) single nucleotide variant Hirschsprung disease 1 [RCV000201301]|not provided [RCV000861134]|not specified [RCV000121297] Chr4:55102430 [GRCh38]
Chr4:55968597 [GRCh37]
Chr4:4q12		 benign|uncertain significance|not provided
NM_002253.3(KDR):c.2305G>A (p.Val769Ile) single nucleotide variant not specified [RCV000121298] Chr4:55098765 [GRCh38]
Chr4:55964932 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.2674A>G (p.Ile892Val) single nucleotide variant not specified [RCV000121299] Chr4:55096283 [GRCh38]
Chr4:55962450 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.3808A>C (p.Lys1270Gln) single nucleotide variant not specified [RCV000121301] Chr4:55081996 [GRCh38]
Chr4:55948163 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.170G>C (p.Arg57Thr) single nucleotide variant not provided [RCV001356648]|not specified [RCV000121302] Chr4:55118792 [GRCh38]
Chr4:55984959 [GRCh37]
Chr4:4q12		 uncertain significance|not provided
NM_002253.3(KDR):c.406G>A (p.Val136Met) single nucleotide variant not provided [RCV000861192]|not specified [RCV000121303] Chr4:55115364 [GRCh38]
Chr4:55981531 [GRCh37]
Chr4:4q12		 benign|not provided
NM_002253.3(KDR):c.724C>T (p.Leu242Phe) single nucleotide variant Premature ovarian failure [RCV001270196]|not specified [RCV000121304] Chr4:55114200 [GRCh38]
Chr4:55980367 [GRCh37]
Chr4:4q12		 likely pathogenic|not provided
NM_002253.3(KDR):c.787C>T (p.Pro263Ser) single nucleotide variant not specified [RCV000121305] Chr4:55114137 [GRCh38]
Chr4:55980304 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.794C>T (p.Ser265Leu) single nucleotide variant not specified [RCV000121306] Chr4:55114130 [GRCh38]
Chr4:55980297 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.895C>T (p.Arg299Trp) single nucleotide variant not specified [RCV000121307] Chr4:55113385 [GRCh38]
Chr4:55979552 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.889G>A (p.Val297Ile) single nucleotide variant not specified [RCV000121308] Chr4:55113391 [GRCh38]
Chr4:55979558 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.1055C>T (p.Ala352Val) single nucleotide variant not provided [RCV000865154]|not specified [RCV000121309] Chr4:55110690 [GRCh38]
Chr4:55976857 [GRCh37]
Chr4:4q12		 benign|not provided
NM_002253.3(KDR):c.1151C>T (p.Thr384Met) single nucleotide variant not provided [RCV001460346]|not specified [RCV000121310] Chr4:55110507 [GRCh38]
Chr4:55976674 [GRCh37]
Chr4:4q12		 likely benign|not provided
NM_002253.3(KDR):c.1116G>C (p.Glu372Asp) single nucleotide variant not provided [RCV000861936]|not specified [RCV000121311] Chr4:55110542 [GRCh38]
Chr4:55976709 [GRCh37]
Chr4:4q12		 benign|not provided
NM_002253.3(KDR):c.1192G>A (p.Val398Ile) single nucleotide variant not specified [RCV000121312] Chr4:55110466 [GRCh38]
Chr4:55976633 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.1987+28C>T single nucleotide variant not specified [RCV000122411] Chr4:55104615 [GRCh38]
Chr4:55970782 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.-1G>T single nucleotide variant not specified [RCV000122412] Chr4:55125294 [GRCh38]
Chr4:55991461 [GRCh37]
Chr4:4q12		 not provided
NM_002253.3(KDR):c.3848+15T>C single nucleotide variant Hemangioma, capillary infantile [RCV000612206] Chr4:55081941 [GRCh38]
Chr4:55948108 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.2360G>A (p.Arg787Gln) single nucleotide variant Malignant tumor of prostate [RCV000149129] Chr4:55098710 [GRCh38]
Chr4:55964877 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2615-23C>T single nucleotide variant Carcinoma of colon [RCV000186516] Chr4:55096365 [GRCh38]
Chr4:55962532 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2656C>A (p.Leu886Ile) single nucleotide variant Carcinoma of colon [RCV000186517] Chr4:55096301 [GRCh38]
Chr4:55962468 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2676T>A (p.Ile892=) single nucleotide variant Carcinoma of colon [RCV000186518] Chr4:55096281 [GRCh38]
Chr4:55962448 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2705T>A (p.Leu902Gln) single nucleotide variant Carcinoma of colon [RCV000186519] Chr4:55096252 [GRCh38]
Chr4:55962419 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2721G>C (p.Lys907Asn) single nucleotide variant Carcinoma of colon [RCV000186520] Chr4:55096236 [GRCh38]
Chr4:55962403 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2380G>A (p.Gly794Arg) single nucleotide variant Carcinoma of colon [RCV000186521] Chr4:55098266 [GRCh38]
Chr4:55964433 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2509+20T>A single nucleotide variant Carcinoma of colon [RCV000186522] Chr4:55098117 [GRCh38]
Chr4:55964284 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2510-27del deletion Carcinoma of colon [RCV000186523] Chr4:55097793 [GRCh38]
Chr4:55963960 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2544G>T (p.Val848=) single nucleotide variant Carcinoma of colon [RCV000186524] Chr4:55097732 [GRCh38]
Chr4:55963899 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2598A>C (p.Ala866=) single nucleotide variant Carcinoma of colon [RCV000186525] Chr4:55097678 [GRCh38]
Chr4:55963845 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.3405-4C>T single nucleotide variant Carcinoma of colon [RCV000186526] Chr4:55088977 [GRCh38]
Chr4:55955144 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.3441C>G (p.Pro1147=) single nucleotide variant Carcinoma of colon [RCV000186527] Chr4:55088937 [GRCh38]
Chr4:55955104 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.3465G>A (p.Glu1155=) single nucleotide variant Carcinoma of colon [RCV000186528] Chr4:55088913 [GRCh38]
Chr4:55955080 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.3487C>T (p.Leu1163Phe) single nucleotide variant Carcinoma of colon [RCV000186529] Chr4:55088891 [GRCh38]
Chr4:55955058 [GRCh37]
Chr4:4q12		 uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
NM_002253.3(KDR):c.2266+1G>T single nucleotide variant not provided [RCV000426580] Chr4:55101896 [GRCh38]
Chr4:55968063 [GRCh37]
Chr4:4q12		 uncertain significance
NM_002253.3(KDR):c.2971+3A>G single nucleotide variant not provided [RCV000483185] Chr4:55094799 [GRCh38]
Chr4:55960966 [GRCh37]
Chr4:4q12		 uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q13.1(chr4:68345-66440622)x3 copy number gain See cases [RCV000511193] Chr4:68345..66440622 [GRCh37]
Chr4:4p16.3-q13.1		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
NM_002253.3(KDR):c.2743A>G (p.Ile915Val) single nucleotide variant not provided [RCV000861318] Chr4:55095651 [GRCh38]
Chr4:55961818 [GRCh37]
Chr4:4q12		 likely benign
NM_002253.3(KDR):c.1137G>A (p.Ala379=) single nucleotide variant not provided [RCV000866539] Chr4:55110521 [GRCh38]
Chr4:55976688 [GRCh37]
Chr4:4q12		 likely benign
NM_002253.3(KDR):c.2022G>C (p.Glu674Asp) single nucleotide variant not provided [RCV000868619] Chr4:55102474 [GRCh38]
Chr4:55968641 [GRCh37]
Chr4:4q12		 likely benign
NM_002253.3(KDR):c.2556T>C (p.Asp852=) single nucleotide variant not provided [RCV000867925] Chr4:55097720 [GRCh38]
Chr4:55963887 [GRCh37]
Chr4:4q12		 likely benign
NM_002253.3(KDR):c.837C>T (p.Thr279=) single nucleotide variant not provided [RCV000926263] Chr4:55113443 [GRCh38]
Chr4:55979610 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.1092-6T>C single nucleotide variant not provided [RCV000864481] Chr4:55110572 [GRCh38]
Chr4:55976739 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.1440C>T (p.Tyr480=) single nucleotide variant not provided [RCV000943497] Chr4:55106783 [GRCh38]
Chr4:55972950 [GRCh37]
Chr4:4q12		 likely benign
NM_002253.3(KDR):c.1593A>G (p.Glu531=) single nucleotide variant not provided [RCV000924663] Chr4:55105884 [GRCh38]
Chr4:55972051 [GRCh37]
Chr4:4q12		 likely benign
NM_002253.3(KDR):c.3888T>A (p.Ser1296=) single nucleotide variant not provided [RCV000869240] Chr4:55080124 [GRCh38]
Chr4:55946291 [GRCh37]
Chr4:4q12		 likely benign
NM_002253.3(KDR):c.3132C>A (p.Ile1044=) single nucleotide variant not provided [RCV000862377] Chr4:55090016 [GRCh38]
Chr4:55956183 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.1256-10C>T single nucleotide variant not provided [RCV000860953] Chr4:55107903 [GRCh38]
Chr4:55974070 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.1638C>T (p.His546=) single nucleotide variant not provided [RCV000863804] Chr4:55105839 [GRCh38]
Chr4:55972006 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.2312C>T (p.Thr771Met) single nucleotide variant Severe Myopia [RCV000785688]|not provided [RCV000862978] Chr4:55098758 [GRCh38]
Chr4:55964925 [GRCh37]
Chr4:4q12		 likely benign|uncertain significance
NM_002253.3(KDR):c.3090G>A (p.Ala1030=) single nucleotide variant not provided [RCV000861204] Chr4:55090058 [GRCh38]
Chr4:55956225 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.204T>C (p.Ser68=) single nucleotide variant not provided [RCV000861467] Chr4:55118758 [GRCh38]
Chr4:55984925 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.1029G>A (p.Thr343=) single nucleotide variant not provided [RCV000863943] Chr4:55110716 [GRCh38]
Chr4:55976883 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.2012G>A (p.Gly671Glu) single nucleotide variant not provided [RCV001200283] Chr4:55102484 [GRCh38]
Chr4:55968651 [GRCh37]
Chr4:4q12		 conflicting interpretations of pathogenicity|uncertain significance
NM_002253.3(KDR):c.1326G>A (p.Thr442=) single nucleotide variant not provided [RCV000865952] Chr4:55107823 [GRCh38]
Chr4:55973990 [GRCh37]
Chr4:4q12		 likely benign
NM_002253.3(KDR):c.1575A>G (p.Ser525=) single nucleotide variant not provided [RCV000867420] Chr4:55105902 [GRCh38]
Chr4:55972069 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.1834T>C (p.Leu612=) single nucleotide variant not provided [RCV000861395] Chr4:55104796 [GRCh38]
Chr4:55970963 [GRCh37]
Chr4:4q12		 benign
NM_002253.3(KDR):c.1596G>A (p.Ala532=) single nucleotide variant not provided [RCV000861466] Chr4:55105881 [GRCh38]
Chr4:55972048 [GRCh37]
Chr4:4q12		 benign
Q1149E single nucleotide variant not provided [RCV001357814] Chr4:55088933 [GRCh38]
Chr4:55955100 [GRCh37]
Chr4:4q12		 uncertain significance
GRCh38/hg38 4q12-21.1(chr4:51891814-76009719)x1 copy number loss Partial albinism [RCV001420508] Chr4:51891814..76009719 [GRCh38]
Chr4:4q12-21.1		 pathogenic
NC_000004.11:g.55963918C>T single nucleotide variant not provided [RCV001437104] Chr4:55097751 [GRCh38]
Chr4:55963918 [GRCh37]
Chr4:4q12		 likely benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6307 AgrOrtholog
COSMIC KDR COSMIC
Ensembl Genes ENSG00000128052 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000263923 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000263923 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
GTEx ENSG00000128052 GTEx
HGNC ID HGNC:6307 ENTREZGENE
Human Proteome Map KDR Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Immunoglobulin UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot
  Tyr_kinase_rcpt_3_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VEGFR-2_TMD UniProtKB/Swiss-Prot
  VEGFR2_rcpt UniProtKB/Swiss-Prot
KEGG Report hsa:3791 UniProtKB/Swiss-Prot
NCBI Gene 3791 ENTREZGENE
OMIM 191306 OMIM
  602089 OMIM
Pfam I-set UniProtKB/Swiss-Prot
  PF00047 UniProtKB/Swiss-Prot
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VEGFR-2_TMD UniProtKB/Swiss-Prot
PharmGKB KDR RGD, PharmGKB
PRINTS VEGFRECEPTR2 UniProtKB/Swiss-Prot
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot
  RECEPTOR_TYR_KIN_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
  TyrKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024RD88 ENTREZGENE
  A0A0H4A777_HUMAN UniProtKB/TrEMBL
  A0A0H4A7S0_HUMAN UniProtKB/TrEMBL
  A0A0H4A7S4_HUMAN UniProtKB/TrEMBL
  A0A0H4ADZ1_HUMAN UniProtKB/TrEMBL
  A0A0H4AF76_HUMAN UniProtKB/TrEMBL
  A0A0H4AF85_HUMAN UniProtKB/TrEMBL
  A0A0U2VU55_HUMAN UniProtKB/TrEMBL
  A0A0U2WZU8_HUMAN UniProtKB/TrEMBL
  A0A0U2X4C8_HUMAN UniProtKB/TrEMBL
  P35968 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A2RRS0 UniProtKB/Swiss-Prot
  B5A925 UniProtKB/Swiss-Prot
  C5IFA0 UniProtKB/Swiss-Prot
  O60723 UniProtKB/Swiss-Prot
  Q14178 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-12-23 KDR  kinase insert domain receptor  KDR  kinase insert domain receptor (a type III receptor tyrosine kinase)  Symbol and/or name change 5135510 APPROVED