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Gene: H2AX (H2A.X variant histone) Homo sapiens
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Symbol: H2AX
Name: H2A.X variant histone
Description: Exhibits enzyme binding activity and histone binding activity. Involved in DNA damage checkpoint. Localizes to the centrosome; nuclear speck; and site of double-strand break. Colocalizes with the chromosome, telomeric region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2A histone family member X; H2A histone family, member X; H2A.X; H2A/X; H2AFX; H2AX histone; histone H2A.x; histone H2AX
Orthologs:
Mus musculus (house mouse) : H2ax (H2A.X variant histone)  MGI  Alliance
Rattus norvegicus (Norway rat) : H2ax (H2A.X variant histone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102025775 (histone H2AX)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100994157 (histone H2AX)
Canis lupus familiaris (dog) : H2AX (H2A.X variant histone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101966907 (histone H2AX)
Sus scrofa (pig) : LOC100522201 (histone H2AX)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,093,874 - 119,095,467 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,964,580 - 118,966,177 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,469,794 - 118,471,387 (-)NCBINCBI36hg18NCBI36
Build 3411118,469,796 - 118,471,387NCBI
Celera11116,121,998 - 116,123,592 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11114,904,032 - 114,905,625 (-)NCBIHuRef
CHM1_111118,850,886 - 118,852,479 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on H2AX
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1346464
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.