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Gene: NOX1 (NADPH oxidase 1) Homo sapiens
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Symbol: NOX1
Name: NADPH oxidase 1
Description: Exhibits Rac GTPase binding activity and superoxide-generating NADPH oxidase activity. Involved in several processes, including cellular stress response to acidic pH; positive regulation of vascular endothelial growth factor production; and superoxide anion generation. Localizes to the NADPH oxidase complex; early endosome; and invadopodium membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX-1; MOX1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1 variant NOH-1L; NADPH oxidase homolog-1; NOH-1; NOH1; NOX-1
Orthologs:
Mus musculus (house mouse) : Nox1 (NADPH oxidase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nox1 (NADPH oxidase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nox1 (NADPH oxidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NOX1 (NADPH oxidase 1)
Canis lupus familiaris (dog) : NOX1 (NADPH oxidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nox1 (NADPH oxidase 1)
Sus scrofa (pig) : NOX1 (NADPH oxidase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X100,843,324 - 100,874,359 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X100,098,313 - 100,129,334 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X99,984,969 - 100,015,990 (-)NCBINCBI36hg18NCBI36
Build 34X99,904,969 - 99,935,343NCBI
CeleraX100,617,105 - 100,648,120 (-)NCBI
Cytogenetic MapXq22.1NCBI
HuRefX89,897,075 - 89,927,719 (-)NCBIHuRef
CHM1_1X99,991,243 - 100,022,267 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NOX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732308
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.