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Gene: CBS (cystathionine beta-synthase) Homo sapiens
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Symbol: CBS
Name: cystathionine beta-synthase
Description: Exhibits several functions, including coenzyme binding activity; cystathionine beta-synthase activity; and heme binding activity. Involved in DNA protection; alpha-amino acid metabolic process; and hydrogen sulfide biosynthetic process. Localizes to cytoplasm and nucleus. Implicated in coronary artery disease; homocystinuria; and neural tube defect.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-thionase; CBSL; cystathionine beta synthase; cystathionine-beta-synthase; HIP4; methylcysteine synthase; serine sulfhydrase
Orthologs:
Mus musculus (house mouse) : Cbs (cystathionine beta-synthase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cbs (cystathionine beta synthase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cbs (cystathionine beta-synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : CBS (cystathionine beta-synthase)
Canis lupus familiaris (dog) : CBS (cystathionine beta-synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cbs (cystathionine beta-synthase)
Sus scrofa (pig) : CBS (cystathionine beta-synthase)
Chlorocebus sabaeus (African green monkey) : CBS (cystathionine beta-synthase)
Heterocephalus glaber (naked mole-rat) : Cbs (cystathionine beta-synthase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2143,053,191 - 43,076,943 (-)EnsemblGRCh38hg38GRCh38
GRCh382143,053,190 - 43,076,861 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372144,473,301 - 44,496,472 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,346,370 - 43,369,490 (-)NCBINCBI36hg18NCBI36
Build 342143,346,369 - 43,369,493NCBI
Celera2129,625,968 - 29,649,139 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2129,891,797 - 29,914,621 (-)NCBIHuRef
CHM1_12144,034,200 - 44,057,827 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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