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Gene: ADRB1 (adrenoceptor beta 1) Homo sapiens
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Symbol: ADRB1
Name: adrenoceptor beta 1
Description: The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADRB1R; adrenergic receptor, beta 1; adrenergic, beta-1-, receptor; B1AR; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor; BETA1AR; RHR
Orthologs:
Mus musculus (house mouse) : Adrb1 (adrenergic receptor, beta 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adrb1 (adrenoceptor beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adrb1 (adrenoceptor beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRB1 (adrenoceptor beta 1)
Canis lupus familiaris (dog) : ADRB1 (adrenoceptor beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adrb1 (adrenoceptor beta 1)
Sus scrofa (pig) : ADRB1 (adrenoceptor beta 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810114,044,047 - 114,046,908 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710115,803,806 - 115,806,667 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610115,793,796 - 115,796,657 (+)NCBINCBI36hg18NCBI36
Build 3410115,793,804 - 115,795,518NCBI
Celera10109,531,177 - 109,534,039 (+)NCBI
Cytogenetic Map10q25.3ENTREZGENE
HuRef10109,429,477 - 109,432,333 (+)NCBIHuRef
CHM1_110116,087,711 - 116,090,573 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

Comparative Map Data
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Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ADRB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731289
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.