(+)-alpha-tocopherol multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein] more ... CTD PMID:12684028 more ... (+)-alpha-tocopherol increases phosphorylation EXP 6480464 alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein CTD PMID:20686688 (+)-pilocarpine multiple interactions EXP 6480464 1 more ... CTD PMID:19927300 (+)-pilocarpine increases activity EXP 6480464 Pilocarpine results in increased activity of MAPK8 protein CTD PMID:19927300 (+)-taxifolin multiple interactions EXP 6480464 taxifolin inhibits the reaction [IFNG protein results in increased phosphorylation of MAPK8 protein] CTD PMID:12044887 (-)-anisomycin increases activity EXP 6480464 Anisomycin results in increased activity of MAPK8 protein CTD PMID:12902192 (-)-anisomycin multiple interactions EXP 6480464 Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15737997 , PMID:18241849 (-)-anisomycin increases phosphorylation ISO RGD:732272 6480464 Anisomycin results in increased phosphorylation of MAPK8 protein CTD PMID:15772366 , PMID:16038797 (-)-anisomycin multiple interactions ISO RGD:621506 6480464 Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15961565 (-)-anisomycin multiple interactions ISO RGD:732272 6480464 4-amino-5-4-methylphenyl-7-tert-butylpyrazolo3, 4-dpyrimidine inhibits the reaction [Anisomycin results in increased phosphorylation of MAPK8 protein] CTD PMID:15772366 (-)-anisomycin increases phosphorylation EXP 6480464 Anisomycin results in increased phosphorylation of MAPK8 protein CTD PMID:12967334 (-)-citrinin increases phosphorylation EXP 6480464 Citrinin results in increased phosphorylation of MAPK8 protein CTD PMID:19361540 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 protein], epigallocatechin gallate inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK8 protein] CTD PMID:19944065 , PMID:31252129 (-)-epigallocatechin 3-gallate increases activity EXP 6480464 epigallocatechin gallate results in increased activity of MAPK8 protein CTD PMID:15705601 (R)-lipoic acid multiple interactions ISO RGD:621506 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA CTD PMID:23830814 (R)-noradrenaline multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK8 protein] CTD PMID:17041759 (R)-noradrenaline increases phosphorylation ISO RGD:621506 6480464 Norepinephrine results in increased phosphorylation of MAPK8 protein CTD PMID:17041759 (R)-Salsolinol increases activity ISO RGD:621506 6480464 salsolinol results in increased activity of MAPK8 protein CTD PMID:11502874 (S)-colchicine increases phosphorylation EXP 6480464 Colchicine results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 (S)-colchicine multiple interactions EXP 6480464 TP53 protein affects the reaction [Colchicine results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 (S)-naringenin increases phosphorylation EXP 6480464 naringenin results in increased phosphorylation of MAPK8 protein CTD PMID:27838343 (S)-nicotine multiple interactions EXP 6480464 Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11592233 , PMID:20727180 (S)-nicotine increases activity ISO RGD:621506 6480464 Nicotine results in increased activity of MAPK8 protein CTD PMID:17021677 (S)-nicotine multiple interactions ISO RGD:621506 6480464 Nicotine promotes the reaction [MAPK8 protein results in increased phosphorylation of JUN protein] CTD PMID:17021677 (S)-nicotine increases expression ISO RGD:621506 6480464 Nicotine results in increased expression of MAPK8 mRNA CTD PMID:20426880 (S)-nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:20727180 (S)-nicotine increases phosphorylation ISO RGD:732272 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:21511693 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO RGD:732272 6480464 o more ... CTD PMID:18840457 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [o, p'-DDT results in increased phosphorylation of MAPK8 protein] CTD PMID:20678559 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases phosphorylation EXP 6480464 o, p'-DDT results in increased phosphorylation of MAPK8 protein CTD PMID:20678559 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose multiple interactions ISO RGD:732272 6480464 beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein], beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:30721698 1,2-dichloroethane decreases expression ISO RGD:732272 6480464 ethylene dichloride results in decreased expression of MAPK8 mRNA CTD PMID:28960355 1,2-dimethylhydrazine decreases expression ISO RGD:732272 6480464 1, 2-Dimethylhydrazine results in decreased expression of MAPK8 mRNA CTD PMID:22206623 1,3-dichloropropan-2-ol increases phosphorylation ISO RGD:621506 6480464 1, 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein CTD PMID:26143167 1,3-dichloropropan-2-ol multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [1, 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein] CTD PMID:29248572 1,3-dichloropropan-2-ol increases phosphorylation ISO RGD:732272 6480464 1, 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein CTD PMID:29248572 1,3-Dinitropyrene increases phosphorylation ISO RGD:732272 6480464 1, 3-dinitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 1,4-phenylenediamine increases phosphorylation EXP 6480464 4-phenylenediamine results in increased phosphorylation of MAPK8 protein CTD PMID:23172806 1,8-cineole multiple interactions EXP 6480464 Eucalyptol inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased phosphorylation of MAPK8 protein] CTD PMID:23872422 1-chloro-2,4,6-trinitrobenzene increases phosphorylation ISO RGD:732272 6480464 Picryl Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:20381601 1-chloro-2,4-dinitrobenzene increases phosphorylation EXP 6480464 Dinitrochlorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:18495191 1-fluoro-2,4-dinitrobenzene increases phosphorylation EXP 6480464 Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 1-fluoro-2,4-dinitrobenzene multiple interactions EXP 6480464 Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 1-hydroxy-2-naphthoic acid multiple interactions ISO RGD:732272 6480464 1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein] CTD PMID:21667204 1-nitropyrene increases phosphorylation ISO RGD:732272 6480464 1-nitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of MAPK8 mRNA CTD PMID:16029874 17beta-estradiol multiple interactions ISO RGD:621506 6480464 Estradiol inhibits the reaction [Gentamicins results in increased activity of MAPK8 protein] CTD PMID:20074632 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone multiple interactions ISO RGD:732272 6480464 2' more ... CTD PMID:31029725 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone increases phosphorylation ISO RGD:732272 6480464 2' more ... CTD PMID:31029725 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:22543052 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 ERN1 protein affects the reaction [2 more ... CTD PMID:22543052 2,3',4,4',5-Pentachlorobiphenyl multiple interactions ISO RGD:621506 6480464 MAPK8 affects the reaction [2 more ... CTD PMID:26519956 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:732272 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects response to substance EXP 6480464 MAPK8 affects the susceptibility to Tetrachlorodibenzodioxin CTD PMID:9677421 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK8 protein CTD PMID:24469321 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732272 6480464 Tetrachlorodibenzodioxin affects the expression of MAPK8 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732272 6480464 Tetrachlorodibenzodioxin results in decreased expression of MAPK8 mRNA CTD PMID:19465110 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:732272 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK8 protein CTD PMID:20181658 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732272 6480464 MAPK8 protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of INSR protein] more ... CTD PMID:20181658 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 1 more ... CTD PMID:16619036 , PMID:24469321 2,3,7,8-tetrachlorodibenzodioxine increases response to substance EXP 6480464 MAPK8 results in increased susceptibility to Tetrachlorodibenzodioxin CTD PMID:9677421 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:621506 6480464 Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA CTD PMID:23537331 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO RGD:621506 6480464 Verapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15936777 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases phosphorylation ISO RGD:621506 6480464 4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein CTD PMID:30790395 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions ISO RGD:621506 6480464 gastrodin inhibits the reaction [4-iodo-2 more ... CTD PMID:30790395 2-acetamidofluorene multiple interactions ISO RGD:621506 6480464 2-Acetylaminofluorene affects the phosphorylation of and affects the activity of MAPK8 protein CTD PMID:17546627 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... 2-amino-2-deoxy-D-glucopyranose increases phosphorylation EXP 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 2-butoxyethanol decreases expression ISO RGD:732272 6480464 n-butoxyethanol results in decreased expression of MAPK8 mRNA CTD PMID:19812364 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO RGD:732272 6480464 6-methyl-2-phenylethynylpyridine promotes the reaction [Biological Products results in increased phosphorylation of MAPK8 protein] CTD PMID:29458170 2-trans,6-trans-farnesyl diphosphate multiple interactions ISO RGD:732272 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 3',5'-cyclic GMP increases activity EXP 6480464 Cyclic GMP analog results in increased activity of MAPK8 protein CTD PMID:11051267 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions ISO RGD:621506 6480464 Puromycin Aminonucleoside binds to and results in increased activity of MAPK8 protein CTD PMID:15351692 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:621506 6480464 tetrabromobisphenol A results in decreased expression of MAPK8 mRNA CTD PMID:28970181 3,3',5,5'-tetrabromobisphenol A increases phosphorylation EXP 6480464 tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein CTD PMID:30766661 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein], diphenyleneiodonium inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein] CTD PMID:30766661 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [puag-haad results in increased expression of MAPK8 mRNA] CTD PMID:28780155 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione decreases expression EXP 6480464 bisindolylmaleimide I results in decreased expression of MAPK8 mRNA CTD PMID:28780155 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:732272 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein, beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:30721698 3-methylcholanthrene multiple interactions EXP 6480464 Methylcholanthrene results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16619036 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamic aldehyde results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15964311 3-phenylprop-2-enal multiple interactions ISO RGD:732272 6480464 cinnamic aldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:17868967 3-phenylprop-2-enal increases phosphorylation EXP 6480464 cinnamic aldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:21469739 4,4'-diaminodiphenylmethane increases expression ISO RGD:732272 6480464 4, 4'-diaminodiphenylmethane results in increased expression of MAPK8 mRNA CTD PMID:18648102 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions ISO RGD:732272 6480464 4 more ... CTD PMID:19815690 4-hydroxynon-2-enal increases activity EXP 6480464 4-hydroxy-2-nonenal results in increased activity of MAPK8 protein CTD PMID:11488593 4-hydroxynon-2-enal increases phosphorylation EXP 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein CTD PMID:24825450 4-hydroxynon-2-enal affects response to substance ISO RGD:732272 6480464 MAPK8 protein affects the susceptibility to 4-hydroxy-2-nonenal CTD PMID:17263905 4-hydroxynon-2-enal increases phosphorylation ISO RGD:732272 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein CTD PMID:15064094 4-hydroxynon-2-enal increases activity ISO RGD:732272 6480464 4-hydroxy-2-nonenal results in increased activity of MAPK8 protein CTD PMID:17263905 4-hydroxynon-2-enal multiple interactions ISO RGD:732272 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15064094 , PMID:16322078 4-hydroxynon-2-enal multiple interactions EXP 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein, Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:12684028 4-hydroxyphenyl retinamide increases phosphorylation EXP 6480464 Fenretinide results in increased phosphorylation of MAPK8 protein CTD PMID:16407847 4-hydroxyphenyl retinamide increases activity EXP 6480464 Fenretinide results in increased activity of MAPK8 protein CTD PMID:16407847 4-hydroxyphenyl retinamide multiple interactions EXP 6480464 [IL24 protein co-treated with Fenretinide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:15580305 , PMID:16407847 4-nonylphenol increases phosphorylation ISO RGD:732272 6480464 4-nonylphenol analog results in increased phosphorylation of MAPK8 protein CTD PMID:27086933 4-phenylbutyric acid multiple interactions ISO RGD:621506 6480464 4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK8 protein] CTD PMID:21147958 4-vinylcyclohexene dioxide increases expression ISO RGD:732272 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of MAPK8 mRNA CTD PMID:20829426 5-aza-2'-deoxycytidine decreases expression ISO RGD:732272 6480464 Decitabine results in decreased expression of MAPK8 mRNA CTD PMID:27915011 5-chloro-7-iodoquinolin-8-ol multiple interactions EXP 6480464 [Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:16648635 acetaldehyde increases phosphorylation EXP 6480464 Acetaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:19110045 acetaldehyde increases activity ISO RGD:621506 6480464 Acetaldehyde results in increased activity of MAPK8 protein CTD PMID:10733585 acetaldehyde multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:19110045 acetic acid multiple interactions ISO RGD:621506 6480464 Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:32045587 acetic acid increases phosphorylation ISO RGD:621506 6480464 Acetic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:32045587 acetylleucyl-leucyl-norleucinal increases phosphorylation ISO RGD:732272 6480464 acetylleucyl-leucyl-norleucinal results in increased phosphorylation of MAPK8 protein CTD PMID:15618349 acrolein multiple interactions EXP 6480464 Phenylbutyrates inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein], RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:11329622 , PMID:18951912 acrolein increases phosphorylation EXP 6480464 Acrolein results in increased phosphorylation of MAPK8 protein CTD PMID:11329622 more ... acrolein multiple interactions ISO RGD:621506 6480464 SB 203580 promotes the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:12487375 acrolein increases phosphorylation ISO RGD:621506 6480464 [Acrolein results in increased phosphorylation of MAPK8 protein] which results in increased phosphorylation of JUN protein, Acrolein results in increased phosphorylation of MAPK8 protein CTD PMID:12487375 acrylamide increases phosphorylation ISO RGD:732272 6480464 Acrylamide results in increased phosphorylation of MAPK8 protein CTD PMID:25531190 , PMID:31081568 acrylamide increases expression ISO RGD:621506 6480464 Acrylamide results in increased expression of MAPK8 protein modified form CTD PMID:29426002 acrylamide multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:25531190 , PMID:31081568 ADP multiple interactions EXP 6480464 Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] CTD PMID:24466103 afimoxifene decreases response to substance EXP 6480464 MAPK8 results in decreased susceptibility to afimoxifene CTD PMID:21233418 aldehydo-D-glucosamine multiple interactions EXP 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... aldehydo-D-glucosamine increases phosphorylation EXP 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 aldehydo-D-glucose increases phosphorylation ISO RGD:621506 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 aldehydo-D-glucose multiple interactions EXP 6480464 Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:14505347 all-trans-retinoic acid multiple interactions ISO RGD:732272 6480464 pyrazolanthrone inhibits the reaction [Tretinoin results in increased activity of MAPK8 protein], SPAG9 protein promotes the reaction [Tretinoin results in increased phosphorylation of MAPK8 protein] CTD PMID:16619266 , PMID:21626648 all-trans-retinoic acid increases activity ISO RGD:732272 6480464 Tretinoin results in increased activity of MAPK8 protein CTD PMID:21626648 all-trans-retinoic acid decreases expression ISO RGD:732272 6480464 Tretinoin results in decreased expression of MAPK8 mRNA CTD PMID:22498432 all-trans-retinoic acid increases phosphorylation ISO RGD:732272 6480464 Tretinoin results in increased phosphorylation of MAPK8 protein CTD PMID:16619266 all-trans-retinoic acid decreases phosphorylation ISO RGD:732272 6480464 Tretinoin results in decreased phosphorylation of MAPK8 protein CTD PMID:16084493 alpha-Chaconine multiple interactions ISO RGD:732272 6480464 alpha-chaconine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:25913072 alpha-mangostin increases phosphorylation EXP 6480464 mangostin analog results in increased phosphorylation of MAPK8 protein CTD PMID:28722351 alvocidib multiple interactions EXP 6480464 [alvocidib co-treated with ethyl 2-amino-6-bromo-4-1-cyano-2-ethoxy-2-oxoethyl-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK8 protein, alvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15039284 , PMID:15634644 amidotrizoic acid increases phosphorylation EXP 6480464 Diatrizoate results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 amiloride multiple interactions ISO RGD:732272 6480464 Amiloride inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein] CTD PMID:19815690 amino acid multiple interactions ISO RGD:732272 6480464 Amino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein], H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein]] CTD PMID:25309793 ammonium chloride affects expression ISO RGD:621506 6480464 Ammonium Chloride affects the expression of MAPK8 mRNA CTD PMID:16483693 ammonium chloride multiple interactions ISO RGD:621506 6480464 TLR5 gene mutant form inhibits the reaction [Ammonium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:30508503 ammonium chloride increases phosphorylation ISO RGD:621506 6480464 Ammonium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:30508503 amodiaquine multiple interactions EXP 6480464 [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein, [CYP3A4 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein CTD PMID:31629065 amphetamine multiple interactions ISO RGD:621506 6480464 MAPK8 protein promotes the reaction [Amphetamine results in increased expression of GJA1 protein] CTD PMID:15194466 anethole multiple interactions EXP 6480464 anethole inhibits the reaction [TNF protein results in increased activity of MAPK8 protein] CTD PMID:10871845 aniline increases phosphorylation ISO RGD:621506 6480464 aniline results in increased phosphorylation of MAPK8 protein CTD PMID:16169568 , PMID:18420242 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [5-4-methylphenylmethylene-2-phenylamino-45H-thiazolone results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:14610070 more ... anthra[1,9-cd]pyrazol-6(2H)-one increases expression ISO RGD:621506 6480464 pyrazolanthrone results in increased expression of MAPK8 protein CTD PMID:16046226 anthra[1,9-cd]pyrazol-6(2H)-one decreases phosphorylation ISO RGD:621506 6480464 pyrazolanthrone results in decreased phosphorylation of MAPK8 protein CTD PMID:22085843 , PMID:24833599 anthra[1,9-cd]pyrazol-6(2H)-one decreases activity EXP 6480464 pyrazolanthrone results in decreased activity of MAPK8 protein CTD PMID:12534346 , PMID:21112663 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16687388 more ... anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:732272 6480464 [pyrazolanthrone co-treated with 6 more ... CTD PMID:16374168 more ... Antimony trioxide multiple interactions EXP 6480464 [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein more ... CTD PMID:16112521 Antimony trioxide multiple interactions ISO RGD:732272 6480464 MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein] CTD PMID:16112521 Antimony trioxide increases activity EXP 6480464 antimony trioxide results in increased activity of MAPK8 protein CTD PMID:16112521 apigenin multiple interactions ISO RGD:621506 6480464 Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:25557508 apocynin multiple interactions ISO RGD:732272 6480464 acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:20354174 apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21391979 more ... arachidonic acid multiple interactions EXP 6480464 MAPK8 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein] more ... CTD PMID:19540902 arsane multiple interactions EXP 6480464 Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:14633691 arsane multiple interactions ISO RGD:621506 6480464 Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein more ... CTD PMID:11756236 , PMID:15210857 arsenic atom multiple interactions ISO RGD:621506 6480464 Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein more ... CTD PMID:11756236 , PMID:15210857 arsenic atom multiple interactions EXP 6480464 Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:14633691 arsenic trichloride multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK8 protein] CTD PMID:22696236 arsenic trichloride increases phosphorylation EXP 6480464 arsenic trichloride results in increased phosphorylation of MAPK8 protein CTD PMID:22696236 , PMID:24434654 arsenic trichloride multiple interactions ISO RGD:732272 6480464 MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased activity of AKT1 protein], MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] CTD PMID:22696236 arsenite(3-) decreases expression ISO RGD:732272 6480464 arsenite results in decreased expression of MAPK8 mRNA CTD PMID:18191166 arsenite(3-) increases phosphorylation ISO RGD:732272 6480464 arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:19808956 arsenite(3-) multiple interactions ISO RGD:732272 6480464 arsenite results in increased phosphorylation of and results in increased activity of MAPK8 protein, MAP3K8 protein affects the reaction [arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:15014438 , PMID:19808956 arsenous acid increases activity EXP 6480464 Arsenic Trioxide results in increased activity of MAPK8 protein CTD PMID:11304686 more ... arsenous acid increases phosphorylation ISO RGD:621506 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:21145380 more ... arsenous acid affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to Arsenic Trioxide CTD PMID:16818652 arsenous acid multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein], pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein] CTD PMID:21145380 , PMID:27174766 arsenous acid increases response to substance ISO RGD:732272 6480464 MAPK8 protein results in increased susceptibility to Arsenic Trioxide, MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:16818652 arsenous acid increases response to substance EXP 6480464 MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:20799280 arsenous acid multiple interactions EXP 6480464 [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:14610070 more ... arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MAPK8 protein CTD PMID:17374990 arsenous acid increases phosphorylation ISO RGD:732272 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:15688020 arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:18412143 more ... asbestos multiple interactions ISO RGD:732272 6480464 Asbestos results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:11280724 asiatic acid multiple interactions ISO RGD:732272 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein], asiatic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:30802477 atrazine increases expression EXP 6480464 Atrazine results in increased expression of MAPK8 mRNA CTD PMID:22378314 atrazine decreases expression ISO RGD:621506 6480464 Atrazine results in decreased expression of MAPK8 mRNA CTD PMID:31187311 atropine multiple interactions ISO RGD:621506 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 aureusidin increases phosphorylation ISO RGD:621506 6480464 aureusidin results in increased phosphorylation of MAPK8 protein CTD PMID:31790703 aureusidin multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK8 protein] CTD PMID:31790703 Azaspiracid multiple interactions ISO RGD:732272 6480464 4 more ... CTD PMID:19815690 bafilomycin A1 increases phosphorylation ISO RGD:732272 6480464 bafilomycin A1 results in increased phosphorylation of MAPK8 protein CTD PMID:31310755 baicalein multiple interactions EXP 6480464 baicalein results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:10718847 BAPTA multiple interactions EXP 6480464 1 more ... CTD PMID:19927300 bathocuproine disulfonic acid multiple interactions ISO RGD:621506 6480464 bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] more ... CTD PMID:10941151 more ... benzo[a]pyrene multiple interactions EXP 6480464 Nitrogen Oxides inhibits the reaction [Benzoapyrene results in increased expression of MAPK8 protein], pyrazolanthrone inhibits the reaction [Benzoapyrene results in increased expression of MAPK8 protein] CTD PMID:16041517 benzo[a]pyrene affects methylation EXP 6480464 Benzoapyrene affects the methylation of MAPK8 promoter CTD PMID:27901495 benzo[a]pyrene increases phosphorylation ISO RGD:732272 6480464 Benzoapyrene results in increased phosphorylation of MAPK8 protein CTD PMID:18321868 benzo[a]pyrene multiple interactions ISO RGD:732272 6480464 Curcumin inhibits the reaction [Benzoapyrene results in increased phosphorylation of MAPK8 protein] CTD PMID:18321868 benzo[a]pyrene increases phosphorylation EXP 6480464 Benzoapyrene results in increased phosphorylation of MAPK8 protein CTD PMID:15698582 benzo[a]pyrene increases expression EXP 6480464 Benzoapyrene results in increased expression of MAPK8 protein CTD PMID:16041517 benzo[a]pyrene diol epoxide I increases phosphorylation ISO RGD:732272 6480464 7 more ... CTD PMID:21501596 benzo[a]pyrene diol epoxide I increases phosphorylation EXP 6480464 7 more ... CTD PMID:20382639 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:732272 6480464 AG 1879 inhibits the reaction [7 more ... CTD PMID:21501596 Benzo[a]pyrene-7,8-diol increases phosphorylation EXP 6480464 benzoapyrene 7, 8-dihydrodiol results in increased phosphorylation of MAPK8 protein CTD PMID:15698582 , PMID:22053912 benzyl isothiocyanate increases phosphorylation EXP 6480464 benzyl isothiocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:31587482 benzyl isothiocyanate multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [benzyl isothiocyanate results in increased phosphorylation of MAPK8 protein] CTD PMID:31587482 beta-D-glucosamine multiple interactions EXP 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... beta-D-glucosamine increases phosphorylation EXP 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 beta-hexachlorocyclohexane multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein] CTD PMID:19760616 beta-hexachlorocyclohexane increases phosphorylation ISO RGD:621506 6480464 beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein CTD PMID:19760616 bicuculline multiple interactions ISO RGD:732272 6480464 [Bicuculline co-treated with Ethanol] results in increased expression of MAPK8 protein CTD PMID:29044621 bis(2-chloroethyl) sulfide increases phosphorylation ISO RGD:732272 6480464 Mustard Gas results in increased phosphorylation of MAPK8 protein CTD PMID:18200059 bis(2-ethylhexyl) phthalate increases phosphorylation EXP 6480464 Diethylhexyl Phthalate results in increased phosphorylation of MAPK8 protein CTD PMID:30944277 bisphenol A multiple interactions ISO RGD:621506 6480464 bisphenol A results in increased expression of and results in increased phosphorylation of MAPK8 protein CTD PMID:17322771 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MAPK8 mRNA CTD PMID:29275510 bisphenol A affects expression ISO RGD:621506 6480464 bisphenol A affects the expression of MAPK8 mRNA CTD PMID:25181051 bisphenol A increases phosphorylation ISO RGD:621506 6480464 bisphenol A results in increased phosphorylation of MAPK8 protein CTD PMID:20096755 , PMID:30496632 Bisphenol A diglycidyl ether multiple interactions ISO RGD:621506 6480464 2, 2-bis4-glycidyloxyphenylpropane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]] CTD PMID:27274199 bortezomib multiple interactions EXP 6480464 [[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:12893773 more ... bortezomib increases phosphorylation EXP 6480464 Bortezomib results in increased phosphorylation of MAPK8 protein CTD PMID:18559525 bufalin decreases activity EXP 6480464 bufalin results in decreased activity of MAPK8 protein CTD PMID:21922632 bupropion multiple interactions EXP 6480464 Bupropion results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:21354251 butanal decreases expression EXP 6480464 butyraldehyde results in decreased expression of MAPK8 mRNA CTD PMID:26079696 butylated hydroxyanisole multiple interactions EXP 6480464 Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK8 protein] CTD PMID:16407847 butylated hydroxyanisole multiple interactions ISO RGD:621506 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein] CTD PMID:18593901 butylated hydroxyanisole multiple interactions ISO RGD:732272 6480464 Butylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein] more ... CTD PMID:15989949 more ... butyric acid increases phosphorylation EXP 6480464 Butyric Acid results in increased phosphorylation of MAPK8 protein CTD PMID:28600122 butyric acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:28600122 cadmium atom multiple interactions ISO RGD:732272 6480464 1 more ... CTD PMID:15254339 more ... cadmium atom increases phosphorylation EXP 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:26187450 , PMID:26514923 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein more ... CTD PMID:26187450 more ... cadmium atom increases phosphorylation ISO RGD:732272 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:15212812 , PMID:15254339 cadmium atom decreases response to substance EXP 6480464 MAPK8 mutant form results in decreased susceptibility to Cadmium CTD PMID:10874022 cadmium atom increases phosphorylation ISO RGD:621506 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 cadmium atom affects response to substance ISO RGD:621506 6480464 MAPK8 protein affects the susceptibility to Cadmium CTD PMID:16516943 cadmium atom multiple interactions ISO RGD:621506 6480464 Cadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16568437 cadmium dichloride multiple interactions ISO RGD:732272 6480464 1 more ... CTD PMID:11958953 more ... cadmium dichloride increases response to substance EXP 6480464 MAPK8 protein results in increased susceptibility to Cadmium Chloride CTD PMID:25374377 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of MAPK8 protein modified form CTD PMID:24419708 cadmium dichloride increases phosphorylation ISO RGD:621506 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:18021293 more ... cadmium dichloride increases phosphorylation ISO RGD:732272 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:11958953 , PMID:18348256 cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:10874044 more ... cadmium dichloride increases activity ISO RGD:621506 6480464 Cadmium Chloride results in increased activity of MAPK8 protein CTD PMID:10637132 cadmium dichloride multiple interactions EXP 6480464 1 more ... CTD PMID:21219922 more ... cadmium dichloride multiple interactions ISO RGD:621506 6480464 1 more ... CTD PMID:15618353 more ... cadmium selenide multiple interactions EXP 6480464 [cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK8 mRNA CTD PMID:22342292 cadmium sulfate multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein], cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:14687664 cadmium sulfate multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein], Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:22767315 cadmium sulfate increases phosphorylation ISO RGD:621506 6480464 cadmium sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:22767315 Calcimycin multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA, fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA] CTD PMID:21331654 calcipotriol decreases response to substance ISO RGD:732272 6480464 MAPK8 gene mutant form results in decreased susceptibility to calcipotriene CTD PMID:24046278 calcitriol multiple interactions EXP 6480464 Calcitriol results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:12761878 camptothecin increases phosphorylation EXP 6480464 Camptothecin results in increased phosphorylation of MAPK8 protein CTD PMID:30885713 , PMID:31255635 camptothecin multiple interactions EXP 6480464 MAPK8 protein affects the reaction [Camptothecin results in increased activity of SP1 protein] more ... CTD PMID:30885713 candesartan multiple interactions ISO RGD:732272 6480464 candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:20562518 cantharidic acid increases phosphorylation EXP 6480464 cantharidic acid results in increased phosphorylation of MAPK8 protein CTD PMID:29345422 , PMID:31916385 capsaicin multiple interactions EXP 6480464 5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:17292493 more ... capsaicin increases activity EXP 6480464 Capsaicin results in increased activity of MAPK8 protein CTD PMID:12478662 more ... capsaicin increases phosphorylation EXP 6480464 Capsaicin results in increased phosphorylation of MAPK8 protein CTD PMID:20619260 capsazepine multiple interactions EXP 6480464 capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:22171160 carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of MAPK8 mRNA CTD PMID:24752500 carbon nanotube increases phosphorylation EXP 6480464 Nanotubes, Carbon results in increased phosphorylation of MAPK8 protein CTD PMID:32493873 carnosic acid multiple interactions ISO RGD:621506 6480464 salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:25446857 carnosic acid multiple interactions ISO RGD:732272 6480464 salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:29854073 carnosine multiple interactions ISO RGD:732272 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein], Carnosine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:30802477 celecoxib multiple interactions EXP 6480464 Celecoxib inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein] CTD PMID:16442704 celecoxib multiple interactions ISO RGD:732272 6480464 Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein] CTD PMID:32416088 chalcone multiple interactions ISO RGD:732272 6480464 Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:22155221 chenodeoxycholic acid multiple interactions ISO RGD:732272 6480464 Chenodeoxycholic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein], Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 chlordecone decreases expression ISO RGD:732272 6480464 Chlordecone results in decreased expression of MAPK8 mRNA CTD PMID:29980752 chloroprene increases expression ISO RGD:621506 6480464 Chloroprene results in increased expression of MAPK8 mRNA CTD PMID:23125180 chloroquine multiple interactions ISO RGD:732272 6480464 Chloroquine inhibits the reaction [lipopolysaccharide more ... CTD PMID:22341560 , PMID:28134560 chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]], Chloroquine promotes the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 chlorpromazine multiple interactions ISO RGD:732272 6480464 [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:23238562 chlorpyrifos increases phosphorylation ISO RGD:621506 6480464 Chlorpyrifos results in increased phosphorylation of MAPK8 protein CTD PMID:22714038 cholate increases phosphorylation ISO RGD:732272 6480464 Cholates results in increased phosphorylation of MAPK8 protein CTD PMID:15750181 choline multiple interactions ISO RGD:732272 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein, Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 chromium atom multiple interactions ISO RGD:732272 6480464 Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:21134603 chromium(6+) multiple interactions ISO RGD:732272 6480464 [Arsenates co-treated with chromium hexavalent ion] results in increased expression of MAPK8 protein more ... CTD PMID:19654923 , PMID:19895865 chromium(6+) increases activity EXP 6480464 chromium hexavalent ion results in increased activity of MAPK8 protein CTD PMID:12902192 chromium(6+) multiple interactions EXP 6480464 4-amino-5-4-methylphenyl-7-tert-butylpyrazolo3 more ... CTD PMID:12902192 chromium(6+) increases phosphorylation ISO RGD:732272 6480464 chromium hexavalent ion results in increased phosphorylation of MAPK8 protein CTD PMID:19654923 , PMID:19895865 chromium(6+) increases expression ISO RGD:732272 6480464 chromium hexavalent ion results in increased expression of MAPK8 protein CTD PMID:19895865 chromium(6+) increases phosphorylation EXP 6480464 chromium hexavalent ion results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 chrysophanol affects phosphorylation EXP 6480464 chrysophanic acid affects the phosphorylation of MAPK8 protein CTD PMID:30300626 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with 2 more ... CTD PMID:11592233 more ... cisplatin increases phosphorylation EXP 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:30550853 , PMID:32238696 cisplatin multiple interactions ISO RGD:732272 6480464 hesperetin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:31153982 cisplatin increases phosphorylation ISO RGD:732272 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:31153982 cisplatin increases expression ISO RGD:621506 6480464 Cisplatin results in increased expression of MAPK8 protein modified form CTD PMID:26739623 cisplatin multiple interactions ISO RGD:621506 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form], N-Acetylcysteinamide inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:15147517 , PMID:26739623 cisplatin increases phosphorylation ISO RGD:621506 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:15147517 cisplatin increases expression ISO RGD:732272 6480464 Cisplatin results in increased expression of MAPK8 mRNA CTD PMID:20883750 cobalt dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein], ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:24386346 cobalt dichloride multiple interactions ISO RGD:621506 6480464 iodopravadoline inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein], Protein Kinase Inhibitors inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21925238 , PMID:31472278 cobalt dichloride increases phosphorylation ISO RGD:621506 6480464 cobaltous chloride results in increased phosphorylation of MAPK8 protein CTD PMID:21925238 more ... cobalt dichloride increases phosphorylation EXP 6480464 cobaltous chloride results in increased phosphorylation of MAPK8 protein CTD PMID:19101624 , PMID:24386346 cocaine multiple interactions ISO RGD:732272 6480464 acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:20354174 copper atom multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of MAPK8 mRNA more ... CTD PMID:16648635 more ... copper atom multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:24690739 , PMID:30768131 copper atom multiple interactions ISO RGD:621506 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:10941151 more ... copper(0) multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of MAPK8 mRNA more ... CTD PMID:16648635 more ... copper(0) multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:24690739 , PMID:30768131 copper(0) multiple interactions ISO RGD:621506 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:10941151 more ... copper(II) chloride multiple interactions ISO RGD:621506 6480464 [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein more ... CTD PMID:11239917 , PMID:20920558 copper(II) chloride multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 crocidolite asbestos increases expression ISO RGD:732272 6480464 Asbestos, Crocidolite results in increased expression of MAPK8 mRNA CTD PMID:19446018 crocidolite asbestos increases expression EXP 6480464 Asbestos, Crocidolite results in increased expression of MAPK8 mRNA CTD PMID:25757056 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK8 mRNA] more ... CTD PMID:18316600 more ... curcumin decreases phosphorylation ISO RGD:621506 6480464 Curcumin results in decreased phosphorylation of MAPK8 protein CTD PMID:18332871 curcumin multiple interactions ISO RGD:621506 6480464 Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11981161 more ... curcumin multiple interactions ISO RGD:732272 6480464 Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16678799 more ... curcumin increases expression EXP 6480464 Curcumin results in increased expression of MAPK8 mRNA CTD PMID:16101141 curcumin increases phosphorylation EXP 6480464 Curcumin results in increased phosphorylation of MAPK8 protein CTD PMID:18316600 cyclophosphamide increases phosphorylation ISO RGD:732272 6480464 Cyclophosphamide results in increased phosphorylation of MAPK8 protein CTD PMID:19696094 cyclophosphamide multiple interactions ISO RGD:621506 6480464 Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein, NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19996110 cyclophosphamide multiple interactions ISO RGD:732272 6480464 GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:19696094 cyclosporin A increases expression ISO RGD:621506 6480464 Cyclosporine results in increased expression of MAPK8 protein CTD PMID:10617104 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of MAPK8 mRNA CTD PMID:25562108 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of MAPK8 mRNA CTD PMID:27704156 cypermethrin multiple interactions ISO RGD:732272 6480464 [[[cypermethrin results in decreased expression of MIR155 mRNA] which results in increased expression of BCL6 mRNA] which results in decreased expression of MAP2K4 protein] which results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:29471534 D-glucose increases phosphorylation ISO RGD:621506 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 D-glucose multiple interactions EXP 6480464 Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:14505347 D-mannitol multiple interactions EXP 6480464 Mannitol promotes the reaction [potassium chromateVI results in increased phosphorylation of MAPK8 protein] CTD PMID:10910949 DDT decreases phosphorylation EXP 6480464 DDT results in decreased phosphorylation of MAPK8 protein CTD PMID:14604893 decabromodiphenyl ether affects expression EXP 6480464 decabromobiphenyl ether affects the expression of MAPK8 mRNA CTD PMID:24834073 delphinidin multiple interactions EXP 6480464 delphinidin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15740068 deoxynivalenol decreases activity EXP 6480464 deoxynivalenol results in decreased activity of MAPK8 protein CTD PMID:20708668 deoxynivalenol increases phosphorylation ISO RGD:732272 6480464 deoxynivalenol results in increased phosphorylation of MAPK8 protein CTD PMID:12377986 more ... deoxynivalenol multiple interactions ISO RGD:732272 6480464 4-amino-5-4-methylphenyl-7-tert-butylpyrazolo3 more ... CTD PMID:14644621 more ... deoxynivalenol multiple interactions EXP 6480464 [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein, deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:18485432 more ... desferrioxamine B increases phosphorylation EXP 6480464 Deferoxamine results in increased phosphorylation of MAPK8 protein CTD PMID:20368581 desferrioxamine B multiple interactions EXP 6480464 Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein] CTD PMID:20206247 desipramine multiple interactions EXP 6480464 1 more ... CTD PMID:18606486 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein], Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]] CTD PMID:10807665 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of MAPK8 mRNA CTD PMID:31181236 dexamethasone affects phosphorylation ISO RGD:621506 6480464 Dexamethasone affects the phosphorylation of MAPK8 protein CTD PMID:18234956 dexamethasone multiple interactions ISO RGD:732272 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10874129 more ... diallyl disulfide increases phosphorylation EXP 6480464 diallyl disulfide results in increased phosphorylation of MAPK8 protein CTD PMID:14522920 diallyl disulfide multiple interactions EXP 6480464 diallyl disulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17647244 Diallyl sulfide multiple interactions EXP 6480464 allyl sulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17647244 diarsenic trioxide multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein], pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein] CTD PMID:21145380 , PMID:27174766 diarsenic trioxide increases phosphorylation ISO RGD:732272 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:15688020 diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:18412143 more ... diarsenic trioxide increases activity EXP 6480464 Arsenic Trioxide results in increased activity of MAPK8 protein CTD PMID:11304686 more ... diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MAPK8 protein CTD PMID:17374990 diarsenic trioxide multiple interactions EXP 6480464 [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:14610070 more ... diarsenic trioxide affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to Arsenic Trioxide CTD PMID:16818652 diarsenic trioxide increases phosphorylation ISO RGD:621506 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:21145380 more ... diarsenic trioxide increases response to substance ISO RGD:732272 6480464 MAPK8 protein results in increased susceptibility to Arsenic Trioxide, MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:16818652 diarsenic trioxide increases response to substance EXP 6480464 MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:20799280 diazepam multiple interactions ISO RGD:621506 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 diazinon increases expression ISO RGD:621506 6480464 Diazinon results in increased expression of MAPK8 mRNA CTD PMID:29108742 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21391979 more ... dibutyl phthalate decreases expression ISO RGD:621506 6480464 Dibutyl Phthalate results in decreased expression of MAPK8 mRNA CTD PMID:21266533 diclofenac affects expression EXP 6480464 Diclofenac affects the expression of MAPK8 mRNA CTD PMID:24752500 dicoumarol multiple interactions EXP 6480464 Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein], Dicumarol inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK8 protein] CTD PMID:14701702 , PMID:24466103 dicrotophos decreases expression EXP 6480464 dicrotophos results in decreased expression of MAPK8 mRNA CTD PMID:28302478 Dictamnine multiple interactions EXP 6480464 dictamnine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:30266538 diethylstilbestrol multiple interactions ISO RGD:732272 6480464 Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15171707 diltiazem decreases activity ISO RGD:621506 6480464 Diltiazem results in decreased activity of MAPK8 protein CTD PMID:11937779 dimethylarsinic acid increases expression ISO RGD:732272 6480464 Cacodylic Acid results in increased expression of MAPK8 mRNA CTD PMID:17441966 dimethylarsinic acid decreases expression ISO RGD:621506 6480464 Cacodylic Acid results in decreased expression of MAPK8 mRNA CTD PMID:17481689 dinophysistoxin 1 increases expression EXP 6480464 dinophysistoxin 1 results in increased expression of MAPK8 mRNA CTD PMID:28939011 dioscin increases expression EXP 6480464 dioscin results in increased expression of MAPK8 mRNA CTD PMID:29990575 dioxygen multiple interactions EXP 6480464 dictamnine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10780954 more ... dioxygen increases activity EXP 6480464 Oxygen deficiency results in increased activity of MAPK8 protein CTD PMID:10780954 , PMID:13679210 dioxygen increases phosphorylation ISO RGD:621506 6480464 Oxygen results in increased phosphorylation of MAPK8 protein CTD PMID:20812253 dioxygen multiple interactions ISO RGD:621506 6480464 2 more ... CTD PMID:12892836 , PMID:27274199 dioxygen increases activity ISO RGD:621506 6480464 Oxygen deficiency results in increased activity of MAPK8 protein CTD PMID:12892836 dioxygen increases phosphorylation EXP 6480464 Oxygen deficiency results in increased phosphorylation of MAPK8 protein CTD PMID:19196431 , PMID:30266538 diphenhydramine increases activity EXP 6480464 Diphenhydramine results in increased activity of MAPK8 CTD PMID:17390763 dipyridamole increases activity EXP 6480464 Dipyridamole results in increased activity of MAPK8 protein CTD PMID:11051267 disodium selenite multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:10644709 , PMID:18728404 disodium selenite multiple interactions ISO RGD:732272 6480464 Sodium Selenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein], Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein] CTD PMID:18481333 , PMID:26522834 disodium selenite decreases expression EXP 6480464 Sodium Selenite results in decreased expression of MAPK8 mRNA CTD PMID:18175754 disodium selenite decreases activity EXP 6480464 Sodium Selenite results in decreased activity of MAPK8 protein CTD PMID:10644709 disulfiram multiple interactions ISO RGD:621506 6480464 [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein, bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein] CTD PMID:11239917 disulfiram multiple interactions EXP 6480464 [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein CTD PMID:24690739 disulfiram multiple interactions ISO RGD:732272 6480464 [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein CTD PMID:24690739 donepezil hydrochloride multiple interactions ISO RGD:621506 6480464 Donepezil inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MAPK8 protein] CTD PMID:19345205 dopamine multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein], Glutathione inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:17481858 dopamine increases phosphorylation ISO RGD:732272 6480464 Dopamine results in increased phosphorylation of MAPK8 protein CTD PMID:17481858 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 dorsomorphin multiple interactions ISO RGD:621506 6480464 dorsomorphin inhibits the reaction [Resveratrol results in decreased expression of MAPK8 protein modified form] CTD PMID:27093858 doxorubicin multiple interactions EXP 6480464 [DLJ14 compound co-treated with Doxorubicin] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:15494689 more ... doxorubicin increases phosphorylation ISO RGD:621506 6480464 Doxorubicin results in increased phosphorylation of MAPK8 protein CTD PMID:15623433 more ... doxorubicin increases expression ISO RGD:621506 6480464 Doxorubicin results in increased expression of MAPK8 mRNA CTD PMID:26335259 doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of MAPK8 protein CTD PMID:15917298 more ... doxorubicin multiple interactions ISO RGD:621506 6480464 [Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased expression of MAPK8 mRNA] more ... CTD PMID:18346979 , PMID:26335259 doxorubicin increases response to substance EXP 6480464 MAPK8 protein results in increased susceptibility to Doxorubicin CTD PMID:15917298 doxorubicin increases activity EXP 6480464 Doxorubicin results in increased activity of MAPK8 protein CTD PMID:15880572 doxorubicin affects activity EXP 6480464 Doxorubicin affects the activity of MAPK8 protein CTD PMID:15870702 edaravone increases phosphorylation EXP 6480464 Edaravone results in increased phosphorylation of MAPK8 protein CTD PMID:19954754 edaravone decreases phosphorylation ISO RGD:732272 6480464 Edaravone results in decreased phosphorylation of MAPK8 protein CTD PMID:15824197 efavirenz multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein], Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein] CTD PMID:21958719 efavirenz increases phosphorylation EXP 6480464 efavirenz metabolite results in increased phosphorylation of MAPK8 protein, efavirenz results in increased phosphorylation of MAPK8 protein CTD PMID:21958719 elemental selenium decreases phosphorylation ISO RGD:732272 6480464 Selenium results in decreased phosphorylation of MAPK8 protein CTD PMID:17997286 elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:26187450 elemental selenium decreases expression ISO RGD:732272 6480464 Selenium results in decreased expression of MAPK8 mRNA CTD PMID:28810182 ellagic acid multiple interactions EXP 6480464 [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein CTD PMID:15735102 emetine multiple interactions ISO RGD:732272 6480464 4-amino-5-4-methylphenyl-7-tert-butylpyrazolo3, 4-dpyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK8 protein] CTD PMID:15772366 emetine increases phosphorylation ISO RGD:732272 6480464 Emetine results in increased phosphorylation of MAPK8 protein CTD PMID:15772366 enilconazole increases expression EXP 6480464 enilconazole results in increased expression of MAPK8 mRNA CTD PMID:32201337 entinostat multiple interactions EXP 6480464 [3-4-methylphenylsulfonyl-2-propenenitrile co-treated with entinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15964800 entinostat decreases expression EXP 6480464 entinostat results in decreased expression of MAPK8 mRNA CTD PMID:27188386 eriodictyol multiple interactions ISO RGD:732272 6480464 eriodictyol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21544733 esculetin multiple interactions EXP 6480464 [esculetin co-treated with Paclitaxel] results in increased expression of MAPK8 protein CTD PMID:16051289 esculetin increases phosphorylation EXP 6480464 esculetin results in increased phosphorylation of MAPK8 protein CTD PMID:19786087 esculetin increases expression EXP 6480464 esculetin results in increased expression of MAPK8 protein CTD PMID:16051289 Estragole increases phosphorylation ISO RGD:621506 6480464 estragole results in increased phosphorylation of MAPK8 protein CTD PMID:29054680 etacrynic acid decreases expression EXP 6480464 Ethacrynic Acid results in decreased expression of MAPK8 protein CTD PMID:14556662 ethanol multiple interactions ISO RGD:621506 6480464 Polysaccharides inhibits the reaction [Ethanol results in increased phosphorylation of MAPK8 protein] CTD PMID:19735724 ethanol multiple interactions EXP 6480464 MAPK8 promotes the reaction [Ethanol results in increased expression of and results in increased activity of RUNX2 protein] CTD PMID:32198086 ethanol multiple interactions ISO RGD:732272 6480464 [Bicuculline co-treated with Ethanol] results in increased expression of MAPK8 protein more ... CTD PMID:29044621 ethanol increases phosphorylation EXP 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:28062356 ethanol increases phosphorylation ISO RGD:732272 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:28119953 , PMID:29044621 ethanol increases phosphorylation ISO RGD:621506 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:19735724 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:621506 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein], Egtazic Acid inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein] CTD PMID:11981161 , PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:732272 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein], Egtazic Acid inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:15254339 , PMID:21544200 Evodiamine multiple interactions EXP 6480464 1 more ... CTD PMID:23774672 Evodiamine increases expression EXP 6480464 evodiamine results in increased expression of MAPK8 protein modified form CTD PMID:23774672 farnesyl diphosphate multiple interactions ISO RGD:732272 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 fenvalerate multiple interactions EXP 6480464 fenvalerate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein] CTD PMID:28949029 ferrosoferric oxide multiple interactions EXP 6480464 [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 ferulic acid decreases activity ISO RGD:621506 6480464 ferulic acid results in decreased activity of MAPK8 protein CTD PMID:15363954 ferulic acid multiple interactions ISO RGD:732272 6480464 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21291945 flubendazole increases activity EXP 6480464 flubendazole results in increased activity of MAPK8 protein CTD PMID:32652169 fluorescein 5-isothiocyanate increases phosphorylation EXP 6480464 Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 fluorescein 5-isothiocyanate multiple interactions EXP 6480464 Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein], Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 fluoxetine decreases expression ISO RGD:621506 6480464 Fluoxetine results in decreased expression of MAPK8 mRNA CTD PMID:20924750 flutamide increases expression ISO RGD:621506 6480464 Flutamide results in increased expression of MAPK8 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:732272 6480464 [pyrazolanthrone co-treated with 6 more ... CTD PMID:21528358 more ... folic acid decreases expression ISO RGD:732272 6480464 Folic Acid results in decreased expression of MAPK8 mRNA CTD PMID:25629700 folic acid increases phosphorylation ISO RGD:732272 6480464 Folic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:31447676 fomepizole multiple interactions ISO RGD:732272 6480464 Fomepizole inhibits the reaction [Acetaminophen results in increased phosphorylation of and affects the localization of MAPK8 protein] CTD PMID:30903181 fomepizole affects binding ISO RGD:732272 6480464 Fomepizole binds to MAPK8 protein CTD PMID:30903181 formoterol fumarate multiple interactions ISO RGD:621506 6480464 [Formoterol Fumarate co-treated with desisobutyrylciclesonide] inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein], Formoterol Fumarate inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein] CTD PMID:26003274 fructose increases expression ISO RGD:621506 6480464 Fructose results in increased expression of MAPK8 protein CTD PMID:29430716 fructose multiple interactions ISO RGD:621506 6480464 imoxin inhibits the reaction [Fructose results in increased expression of MAPK8 protein] CTD PMID:29430716 gallic acid multiple interactions EXP 6480464 Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:21420233 gamma-aminobutyric acid multiple interactions ISO RGD:732272 6480464 gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased expression of MAPK8 protein] CTD PMID:29044621 gamma-hexachlorocyclohexane multiple interactions ISO RGD:621506 6480464 Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:23927878 Gastrodin multiple interactions ISO RGD:621506 6480464 gastrodin inhibits the reaction [4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein] CTD PMID:30790395 gefitinib increases phosphorylation EXP 6480464 gefitinib results in increased phosphorylation of MAPK8 protein CTD PMID:20846305 Geniposide pentaacetate multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein] CTD PMID:17651887 Geniposide pentaacetate increases phosphorylation ISO RGD:621506 6480464 pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein CTD PMID:17651887 gentamycin multiple interactions ISO RGD:621506 6480464 CAT protein inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:15936777 more ... gentamycin increases activity ISO RGD:621506 6480464 Gentamicins results in increased activity of MAPK8 protein CTD PMID:20074632 gentamycin increases phosphorylation ISO RGD:621506 6480464 Gentamicins results in increased phosphorylation of MAPK8 protein CTD PMID:16401625 ginkgolide B multiple interactions EXP 6480464 ginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19464278 ginsenoside Rg1 multiple interactions EXP 6480464 ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:24386346 gliclazide multiple interactions ISO RGD:621506 6480464 Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:32045587 gliotoxin multiple interactions ISO RGD:621506 6480464 Gliotoxin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17466404 glucose increases phosphorylation ISO RGD:621506 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 glucose multiple interactions EXP 6480464 Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:14505347 glutathione multiple interactions EXP 6480464 Glutathione deficiency promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein] CTD PMID:16112521 glutathione multiple interactions ISO RGD:621506 6480464 Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:22767315 glutathione multiple interactions ISO RGD:732272 6480464 Glutathione inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein], Glutathione inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:17481858 , PMID:20423716 glyphosate increases expression EXP 6480464 glyphosate results in increased expression of MAPK8 mRNA CTD PMID:31874349 Goe 6976 multiple interactions EXP 6480464 Go 6976 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:28087840 guggulsterone increases activity EXP 6480464 pregna-4 more ... CTD PMID:17475222 GW 4064 multiple interactions EXP 6480464 GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:25496033 GW 4064 increases expression ISO RGD:732272 6480464 GW 4064 results in increased expression of MAPK8 mRNA CTD PMID:26655953 GW 4064 multiple interactions ISO RGD:732272 6480464 GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein], GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 haloperidol increases phosphorylation ISO RGD:621506 6480464 Haloperidol results in increased phosphorylation of MAPK8 protein CTD PMID:17092607 hemin multiple interactions ISO RGD:621506 6480464 Hemin promotes the reaction [Paraquat results in increased phosphorylation of MAPK8 protein] CTD PMID:19080378 hesperetin multiple interactions EXP 6480464 [Cisplatin co-treated with hesperetin] results in decreased phosphorylation of MAPK8 protein CTD PMID:31153982 hesperetin multiple interactions ISO RGD:621506 6480464 hesperetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:19222219 hesperetin multiple interactions ISO RGD:732272 6480464 hesperetin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:31153982 hesperidin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:19110045 hexachlorobenzene increases phosphorylation ISO RGD:621506 6480464 Hexachlorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:23708402 hexadecanoic acid multiple interactions EXP 6480464 Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:21745629 hexadecanoic acid increases expression ISO RGD:621506 6480464 Palmitic Acid results in increased expression of MAPK8 mRNA CTD PMID:30259999 hexadecanoic acid multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA] more ... CTD PMID:30259999 hexadecanoic acid increases phosphorylation ISO RGD:732272 6480464 Palmitic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:21134603 hexadecanoic acid multiple interactions ISO RGD:732272 6480464 Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:21134603 hexadecanoic acid increases phosphorylation EXP 6480464 Palmitic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:21745629 hexamethylene diisocyanate increases phosphorylation EXP 6480464 1, 6-hexamethylene diisocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 hexamethylene diisocyanate multiple interactions EXP 6480464 1, 6-hexamethylene diisocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 histamine multiple interactions ISO RGD:621506 6480464 Histamine inhibits the reaction [decamethrin results in decreased nitrosation of MAPK8 protein] CTD PMID:25299849 homocysteine increases phosphorylation EXP 6480464 Homocysteine results in increased phosphorylation of MAPK8 protein CTD PMID:25888188 homocysteine multiple interactions EXP 6480464 fulvic acid inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK8 protein] CTD PMID:25888188 hydrogen peroxide multiple interactions EXP 6480464 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10910949 more ... hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of MAPK8 mRNA CTD PMID:31521693 hydrogen peroxide increases phosphorylation ISO RGD:621506 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:16284289 more ... hydrogen peroxide increases phosphorylation ISO RGD:732272 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:15064094 , PMID:25496033 hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:10910949 more ... hydrogen peroxide increases activity EXP 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:12215205 , PMID:12902192 hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of MAPK8 protein CTD PMID:21179406 hydrogen peroxide increases activity ISO RGD:732272 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:10843682 more ... hydrogen peroxide increases activity ISO RGD:621506 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:15574683 hydrogen peroxide multiple interactions ISO RGD:621506 6480464 2-4-dimethylaminomethylbenzylidene-5 more ... CTD PMID:11562448 more ... hydrogen peroxide multiple interactions ISO RGD:732272 6480464 Chenodeoxycholic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10843682 more ... hydroquinone O-beta-D-glucopyranoside decreases expression EXP 6480464 Arbutin results in decreased expression of MAPK8 mRNA CTD PMID:17103032 hydroxyurea decreases phosphorylation ISO RGD:621506 6480464 Hydroxyurea results in decreased phosphorylation of MAPK8 protein CTD PMID:15557822 hypochlorous acid multiple interactions EXP 6480464 Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:18156441 icatibant multiple interactions ISO RGD:621506 6480464 icatibant inhibits the reaction [KLK1 protein inhibits the reaction [Gentamicins results in increased phosphorylation of MAPK8 protein]] CTD PMID:16401625 ifosfamide multiple interactions ISO RGD:621506 6480464 morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] CTD PMID:31722249 ifosfamide increases activity ISO RGD:621506 6480464 Ifosfamide results in increased activity of MAPK8 protein CTD PMID:31722249 indoxyl sulfate multiple interactions ISO RGD:732272 6480464 Indican results in increased expression of and results in increased phosphorylation of MAPK8 protein CTD PMID:30849338 indoxyl sulfate increases phosphorylation ISO RGD:621506 6480464 Indican results in increased phosphorylation of MAPK8 protein CTD PMID:32045570 iomeprol increases phosphorylation EXP 6480464 iomeprol results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 isoprenaline multiple interactions ISO RGD:732272 6480464 candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:20562518 isoprenaline increases activity ISO RGD:621506 6480464 Isoproterenol results in increased activity of MAPK8 protein CTD PMID:10591028 isoprenaline multiple interactions ISO RGD:621506 6480464 2-2-piperidin-1-ylethylthioquinazolin-43H-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:15951400 isoprenaline increases phosphorylation ISO RGD:621506 6480464 Isoproterenol results in increased phosphorylation of MAPK8 protein CTD PMID:15951400 isoprenaline increases phosphorylation ISO RGD:732272 6480464 Isoproterenol results in increased phosphorylation of MAPK8 protein CTD PMID:20562518 isorhamnetin multiple interactions ISO RGD:621506 6480464 3-methylquercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:19222219 ivermectin multiple interactions ISO RGD:732272 6480464 Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein] CTD PMID:19168156 kaempferol increases phosphorylation EXP 6480464 kaempferol results in increased phosphorylation of MAPK8 protein CTD PMID:30499162 kanamycin A increases phosphorylation ISO RGD:621506 6480464 Kanamycin results in increased phosphorylation of MAPK8 protein CTD PMID:17570507 ketoconazole increases phosphorylation EXP 6480464 Ketoconazole results in increased phosphorylation of MAPK8 protein CTD PMID:19631732 ketoconazole increases expression ISO RGD:621506 6480464 Ketoconazole results in increased expression of MAPK8 mRNA CTD PMID:25787151 KN-93 multiple interactions ISO RGD:621506 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21933187 kojic acid decreases expression EXP 6480464 kojic acid results in decreased expression of MAPK8 mRNA CTD PMID:16595896 L-1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 L-ascorbic acid multiple interactions EXP 6480464 [Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:20206247 , PMID:24488945 L-cysteine multiple interactions ISO RGD:621506 6480464 [Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK8 protein, MAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency] CTD PMID:11312036 , PMID:11709198 L-methionine increases activity EXP 6480464 Methionine deficiency results in increased activity of MAPK8 protein CTD PMID:11880182 L-methionine multiple interactions ISO RGD:732272 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein, Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 L-methionine multiple interactions ISO RGD:621506 6480464 [Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK8 protein, MAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency] CTD PMID:11312036 , PMID:11709198 lactacystin increases activity ISO RGD:732272 6480464 lactacystin results in increased activity of MAPK8 protein CTD PMID:15618349 lactacystin increases phosphorylation ISO RGD:621506 6480464 lactacystin results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 lactacystin increases activity ISO RGD:621506 6480464 lactacystin results in increased activity of MAPK8 protein CTD PMID:15618349 lead diacetate multiple interactions ISO RGD:621506 6480464 2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:20829427 , PMID:25088297 lead diacetate affects expression ISO RGD:621506 6480464 lead acetate affects the expression of MAPK8 CTD PMID:24293362 lead diacetate increases phosphorylation ISO RGD:621506 6480464 lead acetate results in increased phosphorylation of MAPK8 protein CTD PMID:25088297 lead(II) chloride increases expression EXP 6480464 lead chloride results in increased expression of MAPK8 protein modified form CTD PMID:24419708 lipoic acid multiple interactions ISO RGD:621506 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA CTD PMID:23830814 lipopolysaccharide increases phosphorylation ISO RGD:732272 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:11123339 more ... lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:20307528 more ... lipopolysaccharide multiple interactions EXP 6480464 1 more ... CTD PMID:17698565 more ... lipopolysaccharide increases phosphorylation ISO RGD:621506 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:16934299 more ... lipopolysaccharide multiple interactions ISO RGD:621506 6480464 Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16934299 more ... lipopolysaccharide increases expression ISO RGD:732272 6480464 Lipopolysaccharides results in increased expression of MAPK8 protein modified form CTD PMID:15832817 lipopolysaccharide multiple interactions ISO RGD:732272 6480464 [Lipopolysaccharides co-treated with Eicosapentaenoic Acid] results in decreased phosphorylation of MAPK8 protein more ... CTD PMID:11123339 more ... lipoteichoic acid multiple interactions ISO RGD:732272 6480464 [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein, TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein] CTD PMID:23238562 lithium atom increases expression ISO RGD:621506 6480464 Lithium results in increased expression of MAPK8 protein CTD PMID:18296634 lithium atom increases phosphorylation ISO RGD:621506 6480464 Lithium results in increased phosphorylation of MAPK8 protein CTD PMID:18296634 lithium hydride increases phosphorylation ISO RGD:621506 6480464 Lithium results in increased phosphorylation of MAPK8 protein CTD PMID:18296634 lithium hydride increases expression ISO RGD:621506 6480464 Lithium results in increased expression of MAPK8 protein CTD PMID:18296634 Longikaurin A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein] CTD PMID:28801140 Longikaurin A increases phosphorylation EXP 6480464 longikaurin A results in increased phosphorylation of MAPK8 protein CTD PMID:28801140 lovastatin multiple interactions ISO RGD:621506 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form] CTD PMID:26739623 luteolin multiple interactions EXP 6480464 Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10718847 more ... luteolin increases phosphorylation EXP 6480464 Luteolin results in increased phosphorylation of MAPK8 protein CTD PMID:21601631 LY294002 multiple interactions ISO RGD:732272 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 LY294002 multiple interactions ISO RGD:621506 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16018989 LY294002 multiple interactions EXP 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tricarbonyldichlororuthenium II dimer results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21420390 , PMID:26385185 lycopene decreases expression EXP 6480464 lycopene results in decreased expression of MAPK8 protein CTD PMID:17337101 Magnolol multiple interactions ISO RGD:732272 6480464 magnolol inhibits the reaction [trimethyltin results in increased phosphorylation of MAPK8 protein] CTD PMID:26756313 malonaldehyde multiple interactions ISO RGD:621506 6480464 MAPK8 protein promotes the reaction [Malondialdehyde results in increased expression of COL1A2 mRNA] CTD PMID:11295527 Malonoben multiple interactions EXP 6480464 tyrphostin A9 inhibits the reaction [S100A4 protein results in increased phosphorylation of MAPK8 protein] CTD PMID:16948116 manganese atom increases phosphorylation EXP 6480464 Manganese results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 manganese atom multiple interactions ISO RGD:621506 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 , PMID:32574669 manganese(0) increases phosphorylation EXP 6480464 Manganese results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 manganese(0) multiple interactions ISO RGD:621506 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 , PMID:32574669 manganese(II) chloride increases activity EXP 6480464 manganese chloride results in increased activity of MAPK8 protein CTD PMID:20152896 manganese(II) chloride multiple interactions ISO RGD:621506 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 , PMID:32574669 manganese(II) chloride increases methylation EXP 6480464 manganese chloride results in increased methylation of MAPK8 gene CTD PMID:27913844 manganese(II) chloride increases phosphorylation ISO RGD:621506 6480464 manganese chloride results in increased phosphorylation of MAPK8 protein CTD PMID:24324973 manganese(II) chloride increases phosphorylation EXP 6480464 manganese chloride results in increased phosphorylation of MAPK8 protein CTD PMID:19084589 , PMID:20152896 mangiferin decreases expression ISO RGD:732272 6480464 mangiferin results in decreased expression of MAPK8 mRNA CTD PMID:15135318 Manumycin A multiple interactions ISO RGD:732272 6480464 manumycin inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19739265 marimastat multiple interactions ISO RGD:621506 6480464 marimastat inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein] CTD PMID:15574683 masoprocol multiple interactions EXP 6480464 Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of MAPK8 protein modified form] CTD PMID:17395008 mebendazole increases phosphorylation EXP 6480464 Mebendazole results in increased phosphorylation of MAPK8 protein CTD PMID:20848085 Mecamylamine multiple interactions ISO RGD:621506 6480464 Mecamylamine inhibits the reaction [Potassium deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:18222492 mechlorethamine increases phosphorylation ISO RGD:732272 6480464 Mechlorethamine results in increased phosphorylation of MAPK8 protein CTD PMID:25891025 melatonin increases expression EXP 6480464 Melatonin results in increased expression of MAPK8 protein CTD PMID:19012662 menadione multiple interactions ISO RGD:621506 6480464 Vitamin K 3 results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:19386027 menadione increases activity EXP 6480464 Vitamin K 3 results in increased activity of MAPK8 protein CTD PMID:12215205 menadione affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to Vitamin K 3 CTD PMID:12215205 menadione increases phosphorylation ISO RGD:621506 6480464 Vitamin K 3 results in increased phosphorylation of MAPK8 protein CTD PMID:16310883 mercaptoethanol multiple interactions EXP 6480464 Mercaptoethanol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 mercury dichloride increases phosphorylation ISO RGD:732272 6480464 Mercuric Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:10861847 more ... Mesna multiple interactions ISO RGD:732272 6480464 Mesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:19696094 metam multiple interactions ISO RGD:732272 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:15933225 methotrexate increases phosphorylation ISO RGD:621506 6480464 Methotrexate results in increased phosphorylation of MAPK8 protein CTD PMID:20885979 methotrexate multiple interactions EXP 6480464 MAPK8 gene mutant form inhibits the reaction [Methotrexate results in increased expression of CDKN1A protein] CTD PMID:22183962 methoxychlor increases expression ISO RGD:732272 6480464 Methoxychlor results in increased expression of MAPK8 mRNA CTD PMID:20829426 methylglyoxal multiple interactions EXP 6480464 sulforafan inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:25933243 methylglyoxal multiple interactions ISO RGD:732272 6480464 MAPK8 protein affects the reaction [Pyruvaldehyde results in increased expression of ACP5 mRNA] more ... CTD PMID:31103701 methylglyoxal increases phosphorylation ISO RGD:732272 6480464 Pyruvaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:31103701 methylglyoxal increases phosphorylation EXP 6480464 Pyruvaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:25933243 methylmercury chloride increases phosphorylation ISO RGD:732272 6480464 methylmercuric chloride results in increased phosphorylation of MAPK8 protein CTD PMID:27667695 methylphenidate increases expression ISO RGD:732272 6480464 Methylphenidate results in increased expression of MAPK8 mRNA CTD PMID:22470460 methylseleninic acid increases expression EXP 6480464 methylselenic acid results in increased expression of MAPK8 mRNA CTD PMID:12517777 miconazole increases expression ISO RGD:621506 6480464 Miconazole results in increased expression of MAPK8 mRNA CTD PMID:22262564 microcystin-LR multiple interactions EXP 6480464 [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK8 protein CTD PMID:29984889 mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]] CTD PMID:10807665 minocycline decreases phosphorylation EXP 6480464 Minocycline results in decreased phosphorylation of MAPK8 protein CTD PMID:17872917 mitomycin C multiple interactions EXP 6480464 Mitomycin results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:16186332 mono(2-ethylhexyl) phthalate affects phosphorylation EXP 6480464 mono-2-ethylhexylphthalate affects the phosphorylation of MAPK8 protein CTD PMID:30810372 monodansylcadaverine multiple interactions ISO RGD:732272 6480464 monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:22341560 monosodium L-glutamate decreases expression ISO RGD:621506 6480464 Sodium Glutamate results in decreased expression of MAPK8 mRNA CTD PMID:28954212 morin multiple interactions ISO RGD:621506 6480464 morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] CTD PMID:31722249 muscimol multiple interactions ISO RGD:732272 6480464 Muscimol inhibits the reaction [Ethanol results in increased expression of MAPK8 protein] CTD PMID:29044621 mycophenolic acid multiple interactions EXP 6480464 Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:20302854 mycophenolic acid decreases expression ISO RGD:621506 6480464 Mycophenolic Acid results in decreased expression of MAPK8 protein modified form CTD PMID:20302854 myricitrin multiple interactions EXP 6480464 myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 N(6),N(6)-dimethyladenine multiple interactions ISO RGD:621506 6480464 N6, N6-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15618353 N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide multiple interactions ISO RGD:621506 6480464 Tiapride Hydrochloride inhibits the reaction [4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein] CTD PMID:30790395 N-acetyl-L-cysteine multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:10397638 more ... N-acetyl-L-cysteine decreases phosphorylation EXP 6480464 Acetylcysteine results in decreased phosphorylation of MAPK8 protein CTD PMID:24735948 N-acetyl-L-cysteine multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:17041759 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:12684028 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases phosphorylation ISO RGD:621506 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases response to substance ISO RGD:732272 6480464 MAPK8 gene mutant form results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde CTD PMID:23593480 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:732272 6480464 MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA] CTD PMID:23593480 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions EXP 6480464 N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein, nordy inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:17377739 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions ISO RGD:621506 6480464 MAPK8 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Reactive Oxygen Species], N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17560994 N-methyl-4-phenylpyridinium increases activity ISO RGD:732272 6480464 1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein CTD PMID:11181820 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of MAPK8 mRNA CTD PMID:25234470 N-methyl-4-phenylpyridinium increases activity EXP 6480464 1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein CTD PMID:17240529 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 RNF7 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein] CTD PMID:17240529 N-methyl-N'-nitro-N-nitrosoguanidine increases phosphorylation EXP 6480464 Methylnitronitrosoguanidine results in increased phosphorylation of MAPK8 protein CTD PMID:22001597 N-methyl-N-nitrosourea multiple interactions ISO RGD:732272 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein], MAPK8 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein] CTD PMID:18593901 N-methyl-N-nitrosourea increases phosphorylation ISO RGD:621506 6480464 Methylnitrosourea results in increased phosphorylation of MAPK8 protein CTD PMID:16168987 N-methyl-N-nitrosourea increases activity ISO RGD:621506 6480464 Methylnitrosourea results in increased activity of MAPK8 protein CTD PMID:18593901 N-methyl-N-nitrosourea multiple interactions ISO RGD:621506 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein] more ... CTD PMID:12693035 more ... N-methyl-N-nitrosourea increases activity ISO RGD:732272 6480464 Methylnitrosourea results in increased activity of MAPK8 protein CTD PMID:18593901 N-methyl-N-nitrosourea decreases response to substance ISO RGD:732272 6480464 MAPK8 gene mutant form results in decreased susceptibility to Methylnitrosourea CTD PMID:18593901 N-Nitroso-N-methylurethane multiple interactions ISO RGD:621506 6480464 Nitrosomethylurethane results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:12693035 N-nitrosodiethylamine multiple interactions ISO RGD:732272 6480464 Butylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein] more ... CTD PMID:15989949 more ... N-nitrosodiethylamine multiple interactions ISO RGD:621506 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA, [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK8 mRNA CTD PMID:23830814 N-nitrosodiethylamine increases response to substance ISO RGD:732272 6480464 MAPK8 protein results in increased susceptibility to Diethylnitrosamine, MAPK8 results in increased susceptibility to Diethylnitrosamine CTD PMID:16807293 , PMID:25496033 N-nitrosodiethylamine increases activity ISO RGD:732272 6480464 Diethylnitrosamine results in increased activity of MAPK8 protein CTD PMID:15989949 , PMID:18691550 N-nitrosodimethylamine multiple interactions ISO RGD:621506 6480464 Dimethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:12971962 Narciclasine multiple interactions ISO RGD:732272 6480464 narciclasine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:30738987 naringin multiple interactions ISO RGD:732272 6480464 naringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein] CTD PMID:22198281 neocuproine multiple interactions ISO RGD:621506 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:18056745 nickel dichloride multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21843586 nickel dichloride multiple interactions ISO RGD:732272 6480464 MAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 mRNA], MAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 protein] CTD PMID:17065197 nickel dichloride increases phosphorylation ISO RGD:621506 6480464 nickel chloride results in increased phosphorylation of MAPK8 protein CTD PMID:21843586 nickel sulfate multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein], SB 203580 promotes the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:18495191 nickel sulfate increases phosphorylation ISO RGD:732272 6480464 nickel sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:18467339 nickel sulfate multiple interactions ISO RGD:732272 6480464 MAP3K1 protein affects the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:18467339 nickel sulfate increases phosphorylation EXP 6480464 nickel sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:15588916 more ... niclosamide multiple interactions ISO RGD:732272 6480464 Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:28824321 nicotinamide multiple interactions ISO RGD:621506 6480464 Niacinamide inhibits the reaction [Methylnitrosourea results in increased phosphorylation of MAPK8 protein] CTD PMID:16168987 nicotine multiple interactions EXP 6480464 Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11592233 , PMID:20727180 nicotine increases activity ISO RGD:621506 6480464 Nicotine results in increased activity of MAPK8 protein CTD PMID:17021677 nicotine increases phosphorylation ISO RGD:732272 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:21511693 nicotine multiple interactions ISO RGD:621506 6480464 Nicotine promotes the reaction [MAPK8 protein results in increased phosphorylation of JUN protein] CTD PMID:17021677 nicotine increases expression ISO RGD:621506 6480464 Nicotine results in increased expression of MAPK8 mRNA CTD PMID:20426880 nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:20727180 nitroprusside decreases expression ISO RGD:621506 6480464 Nitroprusside results in decreased expression of MAPK8 protein modified form CTD PMID:20132804 nitroprusside affects response to substance ISO RGD:621506 6480464 MAPK8 protein affects the susceptibility to Nitroprusside CTD PMID:20132804 nitroprusside multiple interactions ISO RGD:621506 6480464 MAPK8 protein affects the susceptibility to [Nitroprusside results in decreased expression of BCL2L1 mRNA] CTD PMID:20132804 nocodazole multiple interactions EXP 6480464 TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 nocodazole increases phosphorylation EXP 6480464 Nocodazole results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 notoginsenoside R1 multiple interactions ISO RGD:621506 6480464 notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK8 protein] CTD PMID:24975829 ochratoxin A multiple interactions ISO RGD:621506 6480464 ochratoxin A results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17651772 ochratoxin A increases phosphorylation EXP 6480464 ochratoxin A results in increased phosphorylation of MAPK8 protein CTD PMID:31154016 okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of MAPK8 mRNA CTD PMID:28939011 oleanolic acid decreases phosphorylation EXP 6480464 Oleanolic Acid analog results in decreased phosphorylation of MAPK8 protein CTD PMID:26612655 olmesartan decreases activity ISO RGD:732272 6480464 olmesartan results in decreased activity of MAPK8 protein CTD PMID:17208988 olmesartan decreases expression ISO RGD:732272 6480464 olmesartan results in decreased expression of MAPK8 protein modified form CTD PMID:17208988 osthole increases phosphorylation EXP 6480464 osthol results in increased phosphorylation of MAPK8 protein CTD PMID:29319219 oxidopamine increases phosphorylation ISO RGD:621506 6480464 Oxidopamine results in increased phosphorylation of MAPK8 protein CTD PMID:25446857 oxidopamine multiple interactions EXP 6480464 puag-haad inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18675900 , PMID:31176653 oxidopamine multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]] more ... CTD PMID:10397638 oxidopamine multiple interactions ISO RGD:621506 6480464 salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:25446857 oxidopamine increases phosphorylation EXP 6480464 Oxidopamine results in increased phosphorylation of MAPK8 protein CTD PMID:18675900 , PMID:31176653 ozone increases phosphorylation EXP 6480464 Ozone results in increased phosphorylation of MAPK8 protein CTD PMID:19536146 p-menthan-3-ol increases phosphorylation EXP 6480464 Menthol results in increased phosphorylation of MAPK8 protein CTD PMID:18955132 paclitaxel increases activity EXP 6480464 Paclitaxel results in increased activity of MAPK8 protein CTD PMID:11160861 paclitaxel increases phosphorylation EXP 6480464 Paclitaxel results in increased phosphorylation of MAPK8 protein CTD PMID:19426673 paclitaxel increases phosphorylation ISO RGD:732272 6480464 Paclitaxel results in increased phosphorylation of MAPK8 protein CTD PMID:11123339 paclitaxel multiple interactions EXP 6480464 [esculetin co-treated with Paclitaxel] results in increased expression of MAPK8 protein more ... CTD PMID:10075725 more ... paclitaxel multiple interactions ISO RGD:732272 6480464 CD14 protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein], ITGAM protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein] CTD PMID:11123339 paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of MAPK8 protein CTD PMID:16051289 paracetamol multiple interactions ISO RGD:732272 6480464 Acetaminophen results in increased activity of and affects the localization of MAPK8 protein more ... CTD PMID:17185352 more ... paracetamol increases phosphorylation ISO RGD:732272 6480464 Acetaminophen results in increased phosphorylation of MAPK8 protein CTD PMID:19931551 more ... paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of MAPK8 mRNA CTD PMID:27761495 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of MAPK8 mRNA CTD PMID:20732408 , PMID:27761495 paracetamol increases response to substance ISO RGD:621506 6480464 MAPK8 results in increased susceptibility to Acetaminophen CTD PMID:11562448 paracetamol multiple interactions ISO RGD:621506 6480464 Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein, MAP2K4 mutant form inhibits the reaction [Acetaminophen results in increased activity of MAPK8 protein] CTD PMID:11562448 paracetamol increases response to substance ISO RGD:732272 6480464 MAPK8 protein results in increased susceptibility to Acetaminophen CTD PMID:18700144 paracetamol multiple interactions EXP 6480464 Acetaminophen results in increased phosphorylation of and affects the activity of MAPK8 protein CTD PMID:17185352 paraquat multiple interactions ISO RGD:621506 6480464 2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16687388 more ... paraquat increases phosphorylation EXP 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:28474156 paraquat increases phosphorylation ISO RGD:732272 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:28215578 paraquat increases phosphorylation ISO RGD:621506 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:16687388 more ... paraquat multiple interactions EXP 6480464 MAPK8 protein affects the reaction [Paraquat results in increased expression of MUC5AC mRNA] more ... CTD PMID:17018646 more ... paroxetine increases activity ISO RGD:621506 6480464 Paroxetine results in increased activity of MAPK8 protein CTD PMID:17728140 paroxetine multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [Paroxetine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:17728140 parthenolide multiple interactions EXP 6480464 parthenolide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16921510 parthenolide multiple interactions ISO RGD:621506 6480464 parthenolide inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA] CTD PMID:30259999 parthenolide increases expression EXP 6480464 parthenolide results in increased expression of MAPK8 mRNA CTD PMID:16921510 PD 168393 multiple interactions EXP 6480464 PD168393 inhibits the reaction [2 more ... CTD PMID:16778083 pentanal decreases expression EXP 6480464 pentanal results in decreased expression of MAPK8 mRNA CTD PMID:26079696 Pentoxifylline increases expression EXP 6480464 Pentoxifylline results in increased expression of MAPK8 protein, Pentoxifylline results in increased expression of MAPK8 protein modified form CTD PMID:20804743 peptidoglycan increases phosphorylation EXP 6480464 Peptidoglycan results in increased phosphorylation of MAPK8 protein CTD PMID:21647617 perfluorooctane-1-sulfonic acid decreases phosphorylation ISO RGD:621506 6480464 perfluorooctane sulfonic acid results in decreased phosphorylation of MAPK8 protein CTD PMID:28973641 perifosine multiple interactions EXP 6480464 [perifosine co-treated with Butyrates] results in increased activity of MAPK8 protein more ... CTD PMID:15781658 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of MAPK8 mRNA CTD PMID:19159669 phenylephrine multiple interactions ISO RGD:621506 6480464 GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:16385079 more ... phenylephrine increases phosphorylation ISO RGD:621506 6480464 Phenylephrine results in increased phosphorylation of MAPK8 protein CTD PMID:10727428 , PMID:16385079 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA more ... CTD PMID:14610070 more ... phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:732272 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein CTD PMID:20172950 more ... phorbol 13-acetate 12-myristate multiple interactions ISO RGD:732272 6480464 Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein], GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 phorbol 13-acetate 12-myristate increases phosphorylation EXP 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein CTD PMID:16838270 more ... phorone multiple interactions ISO RGD:732272 6480464 [phorone co-treated with tert-Butylhydroperoxide] results in increased phosphorylation of MAPK8 protein CTD PMID:20423716 phosgene multiple interactions ISO RGD:621506 6480464 ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein] CTD PMID:21818760 phosgene increases phosphorylation ISO RGD:621506 6480464 Phosgene results in increased phosphorylation of MAPK8 protein CTD PMID:21818760 phthalic anhydride increases phosphorylation EXP 6480464 phthalic anhydride results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 phthalic anhydride multiple interactions EXP 6480464 phthalic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 pipoxolan multiple interactions ISO RGD:732272 6480464 pipoxolan inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:32677756 pirinixic acid increases expression ISO RGD:621506 6480464 pirinixic acid results in increased expression of MAPK8 mRNA CTD PMID:12832660 pirinixic acid increases expression ISO RGD:732272 6480464 pirinixic acid results in increased expression of MAPK8 mRNA CTD PMID:17426115 , PMID:18301758 platycodin D increases activity EXP 6480464 platycodin D results in increased activity of MAPK8 protein CTD PMID:20412017 plitidepsin increases activity EXP 6480464 plitidepsin results in increased activity of MAPK8 protein CTD PMID:18089842 plitidepsin multiple interactions EXP 6480464 AKT1 protein affects the reaction [plitidepsin results in increased activity of MAPK8 protein] CTD PMID:18089842 potassium atom multiple interactions ISO RGD:621506 6480464 Mecamylamine inhibits the reaction [Potassium deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:18222492 potassium atom increases phosphorylation ISO RGD:621506 6480464 Potassium deficiency results in increased phosphorylation of MAPK8 protein CTD PMID:18222492 potassium chromate multiple interactions EXP 6480464 4-4-fluorophenyl-2-4-hydroxyphenyl-5-4-pyridylimidazole inhibits the reaction [potassium chromateVI results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10910949 potassium chromate increases phosphorylation EXP 6480464 potassium chromateVI results in increased phosphorylation of MAPK8 protein CTD PMID:10910949 pramipexole multiple interactions ISO RGD:621506 6480464 pramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:16362428 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:621506 6480464 Pregnenolone Carbonitrile results in increased expression of MAPK8 mRNA CTD PMID:19162173 proanthocyanidin multiple interactions ISO RGD:621506 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25088297 procyanidin B3 multiple interactions ISO RGD:732272 6480464 [Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein more ... CTD PMID:22169119 prodigiosin decreases phosphorylation EXP 6480464 Prodigiosin results in decreased phosphorylation of MAPK8 protein CTD PMID:31077745 progesterone multiple interactions ISO RGD:621506 6480464 Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:16284289 prostaglandin E2 increases activity ISO RGD:732272 6480464 Dinoprostone results in increased activity of MAPK8 protein CTD PMID:16644903 prostaglandin E2 multiple interactions ISO RGD:732272 6480464 L-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK8 protein] CTD PMID:16644903 prostaglandin F2alpha increases phosphorylation ISO RGD:732272 6480464 Dinoprost results in increased phosphorylation of MAPK8 protein CTD PMID:24333336 prostaglandin F2alpha multiple interactions ISO RGD:732272 6480464 resveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein], SRT1720 inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein] CTD PMID:24333336 protein kinase inhibitor multiple interactions EXP 6480464 Protein Kinase Inhibitors inhibits the reaction [tricarbonyldichlororuthenium II dimer results in increased phosphorylation of MAPK8 protein] CTD PMID:26385185 protein kinase inhibitor multiple interactions ISO RGD:621506 6480464 Protein Kinase Inhibitors inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21925238 pterostilbene multiple interactions EXP 6480464 pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein], pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:19447859 , PMID:24154491 puerarin multiple interactions EXP 6480464 arsenic trioxide promotes the reaction [puerarin results in increased expression of MAPK8 protein] CTD PMID:20416161 puerarin increases phosphorylation EXP 6480464 puerarin results in increased phosphorylation of MAPK8 protein CTD PMID:21884717 puerarin increases expression EXP 6480464 puerarin results in increased expression of MAPK8 protein CTD PMID:20416161 pyrrolidine dithiocarbamate multiple interactions ISO RGD:621506 6480464 [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10941151 more ... pyrrolidine dithiocarbamate increases activity ISO RGD:621506 6480464 pyrrolidine dithiocarbamic acid results in increased activity of MAPK8 protein CTD PMID:10658192 quercetin increases phosphorylation EXP 6480464 Quercetin results in increased phosphorylation of MAPK8 protein CTD PMID:18377872 more ... quercetin increases expression EXP 6480464 Quercetin results in increased expression of MAPK8 mRNA, Quercetin results in increased expression of MAPK8 protein modified form CTD PMID:19017364 , PMID:23727915 quercetin multiple interactions EXP 6480464 [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10718847 more ... quinoline multiple interactions EXP 6480464 quinoline analog inhibits the reaction [MAP3K20 protein promotes the reaction [Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein]], quinoline analog results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:15737997 ramipril multiple interactions ISO RGD:621506 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein], Ramipril inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:31062909 razoxane affects activity EXP 6480464 Razoxane affects the activity of MAPK8 CTD PMID:10487526 reactive oxygen species multiple interactions EXP 6480464 [[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15173093 more ... reactive oxygen species multiple interactions ISO RGD:621506 6480464 MAPK8 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Reactive Oxygen Species] CTD PMID:17560994 resiniferatoxin increases activity EXP 6480464 resiniferatoxin results in increased activity of MAPK8 protein CTD PMID:9580328 resveratrol multiple interactions ISO RGD:732272 6480464 [resveratrol results in increased activity of MAPK8 protein] which results in increased phosphorylation of and results in increased activity of TRP53 protein more ... CTD PMID:11933078 more ... resveratrol decreases expression ISO RGD:621506 6480464 resveratrol results in decreased expression of MAPK8 protein modified form CTD PMID:27093858 resveratrol multiple interactions ISO RGD:621506 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:27093858 more ... resveratrol affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to resveratrol CTD PMID:20082299 resveratrol multiple interactions EXP 6480464 MAPK8 protein affects the reaction [resveratrol results in increased expression of PRF1 protein] more ... CTD PMID:15217905 more ... resveratrol increases phosphorylation EXP 6480464 resveratrol results in increased phosphorylation of MAPK8 protein CTD PMID:18347188 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of MAPK8 protein CTD PMID:18089832 resveratrol increases activity ISO RGD:732272 6480464 resveratrol results in increased activity of MAPK8 protein CTD PMID:11933078 , PMID:21679764 resveratrol decreases activity EXP 6480464 resveratrol results in decreased activity of MAPK8 protein CTD PMID:11408617 resveratrol decreases phosphorylation EXP 6480464 resveratrol results in decreased phosphorylation of MAPK8 protein CTD PMID:23437203 rifampicin multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]], Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 rimonabant multiple interactions ISO RGD:732272 6480464 Rimonabant inhibits the reaction [3-2-hydroxy-4-1 more ... CTD PMID:18950629 Ro 31-8220 multiple interactions ISO RGD:621506 6480464 Ro 31-8220 inhibits the reaction [Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein] CTD PMID:11756236 rosmarinic acid decreases phosphorylation ISO RGD:621506 6480464 rosmarinic acid results in decreased phosphorylation of MAPK8 protein CTD PMID:28789951 rotenone increases activity EXP 6480464 Rotenone results in increased activity of MAPK8 protein CTD PMID:10780954 rotenone multiple interactions ISO RGD:621506 6480464 1-1-acetyl-piperidine-4-yl-3-adamantan-1-yl-urea inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:30472438 rotenone increases phosphorylation ISO RGD:621506 6480464 Rotenone results in increased phosphorylation of MAPK8 protein CTD PMID:30472438 rotenone multiple interactions ISO RGD:732272 6480464 Rotenone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:29906494 rotenone increases phosphorylation EXP 6480464 Rotenone results in increased phosphorylation of MAPK8 protein CTD PMID:31648047 rotenone increases activity ISO RGD:732272 6480464 Rotenone results in increased activity of MAPK8 protein CTD PMID:11181820 rotenone multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]] more ... CTD PMID:10780954 more ... rottlerin multiple interactions EXP 6480464 rottlerin inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein], rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:15917298 , PMID:20599481 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein more ... CTD PMID:14701702 , PMID:16112521 salubrinal multiple interactions ISO RGD:621506 6480464 [salubrinal results in increased expression of EIF2S1 protein modified form] which results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 salubrinal multiple interactions EXP 6480464 salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein], salubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:20686688 , PMID:21809093 Salvianolic acid A multiple interactions ISO RGD:732272 6480464 salvianolic acid A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:31654708 sanguinarine multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [sanguinarine results in increased phosphorylation of MAPK8 protein] CTD PMID:19135517 sanguinarine increases phosphorylation EXP 6480464 sanguinarine results in increased phosphorylation of MAPK8 protein CTD PMID:19135517 sappanchalcone increases phosphorylation EXP 6480464 sappanchalcone results in increased phosphorylation of MAPK8 protein CTD PMID:21963806 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [4-vinyl-2 more ... CTD PMID:13679210 more ... SB 203580 increases phosphorylation ISO RGD:621506 6480464 SB 203580 results in increased phosphorylation of MAPK8 protein CTD PMID:28087833 SB 203580 decreases activity EXP 6480464 SB 203580 results in decreased activity of MAPK8 protein CTD PMID:18089842 SB 203580 multiple interactions ISO RGD:621506 6480464 SB 203580 promotes the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:12487375 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 selenium atom decreases phosphorylation ISO RGD:732272 6480464 Selenium results in decreased phosphorylation of MAPK8 protein CTD PMID:17997286 selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:26187450 selenium atom decreases expression ISO RGD:732272 6480464 Selenium results in decreased expression of MAPK8 mRNA CTD PMID:28810182 selenomethionine multiple interactions EXP 6480464 Selenomethionine inhibits the reaction [Spermine results in increased activity of MAPK8 protein] CTD PMID:20121705 serpentine asbestos multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein] CTD PMID:24735948 serpentine asbestos increases phosphorylation EXP 6480464 Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein CTD PMID:15882436 , PMID:24735948 sertraline multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein], Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17728140 silibinin increases phosphorylation EXP 6480464 Silybin results in increased phosphorylation of MAPK8 protein CTD PMID:16777994 silibinin multiple interactions EXP 6480464 pifithrin inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein], pyrazolanthrone inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein] CTD PMID:16777994 silicon dioxide decreases expression ISO RGD:732272 6480464 Silicon Dioxide results in decreased expression of MAPK8 mRNA CTD PMID:19073995 silicon dioxide increases phosphorylation EXP 6480464 Silicon Dioxide analog results in increased phosphorylation of MAPK8 protein, Silicon Dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:24844442 more ... silicon dioxide increases phosphorylation ISO RGD:732272 6480464 Silicon Dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:27616297 silver atom affects expression EXP 6480464 Silver affects the expression of MAPK8 mRNA CTD PMID:22342292 silver atom increases phosphorylation ISO RGD:621506 6480464 Silver results in increased phosphorylation of MAPK8 protein CTD PMID:26702581 silver(0) affects expression EXP 6480464 Silver affects the expression of MAPK8 mRNA CTD PMID:22342292 silver(0) increases phosphorylation ISO RGD:621506 6480464 Silver results in increased phosphorylation of MAPK8 protein CTD PMID:26702581 simvastatin multiple interactions ISO RGD:732272 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]], Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein] CTD PMID:18310456 simvastatin increases activity ISO RGD:732272 6480464 Simvastatin results in increased activity of MAPK8 protein CTD PMID:15187114 simvastatin multiple interactions ISO RGD:621506 6480464 Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:18047562 sirolimus multiple interactions EXP 6480464 [7-hydroxystaurosporine co-treated with Sirolimus] results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased phosphorylation of MAPK8 protein] CTD PMID:15767555 sodium arsenate increases phosphorylation EXP 6480464 sodium arsenate results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 sodium arsenite multiple interactions EXP 6480464 MAPK8 mutant form inhibits the reaction [sodium arsenite results in increased expression of ELK1 mRNA] more ... CTD PMID:21642427 more ... sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of MAPK8 mRNA CTD PMID:29301061 sodium arsenite decreases expression ISO RGD:732272 6480464 sodium arsenite results in decreased expression of MAPK8 mRNA CTD PMID:31233874 sodium arsenite increases phosphorylation ISO RGD:621506 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:11408547 more ... sodium arsenite increases expression ISO RGD:621506 6480464 sodium arsenite results in increased expression of MAPK8 mRNA, sodium arsenite results in increased expression of MAPK8 protein CTD PMID:24497207 , PMID:27966075 sodium arsenite increases activity ISO RGD:621506 6480464 sodium arsenite results in increased activity of MAPK8 protein CTD PMID:17658681 sodium arsenite decreases expression ISO RGD:621506 6480464 sodium arsenite results in decreased expression of MAPK8 protein CTD PMID:19072884 sodium arsenite multiple interactions ISO RGD:621506 6480464 2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11312036 more ... sodium arsenite increases phosphorylation ISO RGD:732272 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:16973625 more ... sodium arsenite increases expression ISO RGD:732272 6480464 sodium arsenite results in increased expression of MAPK8 mRNA more ... CTD PMID:19822182 more ... sodium arsenite multiple interactions ISO RGD:732272 6480464 CDKN1B protein affects the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16973625 more ... sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:12482858 more ... sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of MAPK8 protein modified form CTD PMID:23219847 sodium arsenite increases activity EXP 6480464 sodium arsenite results in increased activity of MAPK8 protein CTD PMID:22706169 , PMID:23219847 sodium arsenite increases response to substance EXP 6480464 MAPK8 protein results in increased susceptibility to sodium arsenite CTD PMID:21726611 sodium dichromate affects expression ISO RGD:621506 6480464 sodium bichromate affects the expression of MAPK8 mRNA CTD PMID:11960910 sodium fluoride increases expression ISO RGD:621506 6480464 Sodium Fluoride results in increased expression of MAPK8 mRNA CTD PMID:30633982 sodium fluoride increases expression ISO RGD:732272 6480464 Sodium Fluoride results in increased expression of MAPK8 mRNA CTD PMID:32156525 sodium fluoride multiple interactions ISO RGD:732272 6480464 PTH protein promotes the reaction [Sodium Fluoride results in increased expression of MAPK8 mRNA] CTD PMID:32156525 sodium fluoride multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of MAPK8 mRNA] CTD PMID:30633982 Soman increases phosphorylation ISO RGD:621506 6480464 Soman results in increased phosphorylation of MAPK8 protein CTD PMID:21971501 Soman multiple interactions ISO RGD:621506 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 sorafenib multiple interactions EXP 6480464 [Bortezomib co-treated with Sorafenib] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:16985072 , PMID:30187994 sorafenib decreases phosphorylation EXP 6480464 Sorafenib results in decreased phosphorylation of MAPK8 protein CTD PMID:30187994 spermine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Spermine results in increased activity of MAPK8 protein], Selenomethionine inhibits the reaction [Spermine results in increased activity of MAPK8 protein] CTD PMID:20121705 spermine increases activity EXP 6480464 Spermine results in increased activity of MAPK8 protein CTD PMID:20121705 SR 144528 multiple interactions ISO RGD:732272 6480464 SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK8 protein] CTD PMID:24184660 stavudine decreases phosphorylation EXP 6480464 Stavudine results in decreased phosphorylation of MAPK8 protein CTD PMID:27041070 streptozocin multiple interactions EXP 6480464 Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein] CTD PMID:25541468 streptozocin increases phosphorylation ISO RGD:621506 6480464 Streptozocin results in increased phosphorylation of MAPK8 protein CTD PMID:31062909 streptozocin multiple interactions ISO RGD:621506 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:31062909 streptozocin increases phosphorylation ISO RGD:732272 6480464 Streptozocin results in increased phosphorylation of MAPK8 protein CTD PMID:30802477 streptozocin multiple interactions ISO RGD:732272 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:26522834 , PMID:30802477 succimer multiple interactions ISO RGD:732272 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of MAPK8 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of MAPK8 mRNA CTD PMID:21641980 , PMID:26378955 sucrose multiple interactions EXP 6480464 Oligosaccharides inhibits the reaction [[Sucrose co-treated with Dietary Fats] affects the expression of MAPK8 mRNA] CTD PMID:31181236 sulforaphane increases activity EXP 6480464 sulforafan results in increased activity of MAPK8 protein CTD PMID:16201852 sulforaphane multiple interactions EXP 6480464 sulforafan inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:25933243 sulindac multiple interactions EXP 6480464 CDKN1A protein promotes the reaction [Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:15713900 more ... sulindac increases phosphorylation ISO RGD:732272 6480464 Sulindac results in increased phosphorylation of MAPK8 protein CTD PMID:17292881 sulindac increases expression ISO RGD:732272 6480464 Sulindac results in increased expression of MAPK8 mRNA CTD PMID:17292881 sulindac sulfide increases activity EXP 6480464 sulindac sulfide results in increased activity of MAPK8 protein CTD PMID:11051267 sulindac sulfone increases activity EXP 6480464 sulindac sulfone results in increased activity of MAPK8 protein CTD PMID:11051267 more ... sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of MAPK8 mRNA CTD PMID:31533062 tacrolimus hydrate decreases activity ISO RGD:621506 6480464 Tacrolimus results in decreased activity of MAPK8 protein CTD PMID:12892836 tacrolimus hydrate multiple interactions ISO RGD:621506 6480464 Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein] CTD PMID:12892836 tamoxifen multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK8 protein] CTD PMID:14645110 tamoxifen multiple interactions ISO RGD:732272 6480464 Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein], Tamoxifen inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 tamoxifen increases activity EXP 6480464 Tamoxifen results in increased activity of MAPK8 protein CTD PMID:14645110 Tanshinone I multiple interactions ISO RGD:732272 6480464 tanshinone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:29906494 taurine decreases expression ISO RGD:621506 6480464 Taurine results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 taurine multiple interactions ISO RGD:621506 6480464 [[Taurine binds to Zinc] which co-treated with polyN-vinylpyrrolidine] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 , PMID:27501764 taurocholic acid multiple interactions ISO RGD:732272 6480464 NR1H4 gene mutant form promotes the reaction [Taurocholic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:28505368 tenofovir disoproxil fumarate affects phosphorylation EXP 6480464 Tenofovir affects the phosphorylation of MAPK8 protein CTD PMID:27041070 tert-butyl hydroperoxide multiple interactions ISO RGD:732272 6480464 [phorone co-treated with tert-Butylhydroperoxide] results in increased phosphorylation of MAPK8 protein CTD PMID:20423716 tert-butyl hydroperoxide multiple interactions EXP 6480464 LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein] CTD PMID:28063877 tert-butyl hydroperoxide increases phosphorylation EXP 6480464 tert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein CTD PMID:28063877 tetracaine multiple interactions ISO RGD:621506 6480464 1 more ... CTD PMID:11981161 tetracaine increases phosphorylation ISO RGD:621506 6480464 Tetracaine results in increased phosphorylation of MAPK8 protein CTD PMID:11981161 tetrachloromethane increases phosphorylation ISO RGD:732272 6480464 Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein CTD PMID:20589743 more ... tetrachloromethane increases expression ISO RGD:621506 6480464 Carbon Tetrachloride results in increased expression of MAPK8 mRNA CTD PMID:31150632 tetrachloromethane increases phosphorylation ISO RGD:621506 6480464 Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein CTD PMID:17285312 , PMID:19066852 tetrachloromethane multiple interactions ISO RGD:732272 6480464 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein], Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein] CTD PMID:20589743 , PMID:21291945 tetramethylpyrazine multiple interactions EXP 6480464 tetramethylpyrazine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:26404762 thapsigargin increases phosphorylation ISO RGD:621506 6480464 Thapsigargin results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 , PMID:32574669 thapsigargin multiple interactions ISO RGD:732272 6480464 imoxin inhibits the reaction [Thapsigargin results in increased phosphorylation of MAPK8 protein] CTD PMID:24150608 thapsigargin increases phosphorylation ISO RGD:732272 6480464 Thapsigargin results in increased phosphorylation of MAPK8 protein CTD PMID:24150608 thapsigargin multiple interactions ISO RGD:621506 6480464 GW 506033X inhibits the reaction [Thapsigargin results in increased phosphorylation of MAPK8 protein] CTD PMID:32574669 thimerosal increases phosphorylation EXP 6480464 Thimerosal results in increased phosphorylation of MAPK8 protein CTD PMID:18495191 thimerosal increases expression EXP 6480464 Thimerosal results in increased expression of MAPK8 mRNA CTD PMID:27188386 thioacetamide multiple interactions ISO RGD:621506 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA, [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK8 mRNA CTD PMID:23830814 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of MAPK8 mRNA CTD PMID:22342292 titanium dioxide multiple interactions EXP 6480464 [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 titanium dioxide increases phosphorylation EXP 6480464 titanium dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 titanium dioxide increases expression ISO RGD:732272 6480464 titanium dioxide results in increased expression of MAPK8 mRNA CTD PMID:23557971 tofacitinib multiple interactions EXP 6480464 tofacitinib inhibits the reaction [OSM protein results in increased phosphorylation of MAPK8 protein] CTD PMID:21548952 trans-anethole multiple interactions EXP 6480464 anethole inhibits the reaction [TNF protein results in increased activity of MAPK8 protein] CTD PMID:10871845 trans-chalcone multiple interactions ISO RGD:732272 6480464 Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:22155221 tributylstannane increases phosphorylation EXP 6480464 tributyltin results in increased phosphorylation of MAPK8 protein CTD PMID:21626652 tricetin multiple interactions EXP 6480464 tricetin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:31176653 trichostatin A multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:15781658 more ... trichostatin A affects expression EXP 6480464 trichostatin A affects the expression of MAPK8 mRNA CTD PMID:28542535 trichostatin A decreases expression EXP 6480464 trichostatin A results in decreased expression of MAPK8 mRNA CTD PMID:22723015 , PMID:26272509 trifluoperazine multiple interactions EXP 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trifluoperazine multiple interactions ISO RGD:732272 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trifluoperazine multiple interactions ISO RGD:621506 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trimellitic anhydride increases phosphorylation EXP 6480464 trimellitic anhydride results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 trimellitic anhydride multiple interactions EXP 6480464 trimellitic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 trimethylarsine oxide decreases expression ISO RGD:621506 6480464 trimethylarsine oxide results in decreased expression of MAPK8 mRNA CTD PMID:17481689 trimethyltin multiple interactions ISO RGD:732272 6480464 magnolol inhibits the reaction [trimethyltin results in increased phosphorylation of MAPK8 protein] CTD PMID:26756313 trimethyltin increases phosphorylation ISO RGD:732272 6480464 trimethyltin results in increased phosphorylation of MAPK8 protein CTD PMID:26756313 troglitazone decreases expression ISO RGD:732272 6480464 troglitazone results in decreased expression of MAPK8 mRNA CTD PMID:28973697 troglitazone multiple interactions EXP 6480464 troglitazone results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15064713 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO RGD:621506 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 tunicamycin increases expression ISO RGD:732272 6480464 Tunicamycin results in increased expression of MAPK8 mRNA CTD PMID:17127020 tunicamycin increases phosphorylation ISO RGD:621506 6480464 Tunicamycin results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein], RTKI cpd inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:11329622 , PMID:26514923 tyrphostin AG 1478 multiple interactions ISO RGD:621506 6480464 RTKI cpd inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein] CTD PMID:15574683 U-73122 multiple interactions EXP 6480464 1-6-3-methoxyestra-1 more ... CTD PMID:19927300 urethane increases expression EXP 6480464 Urethane results in increased expression of MAPK8 mRNA CTD PMID:28818685 ursolic acid multiple interactions ISO RGD:621506 6480464 2 more ... CTD PMID:27274199 valproic acid decreases expression ISO RGD:732272 6480464 Valproic Acid results in decreased expression of MAPK8 mRNA CTD PMID:21427059 valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of MAPK8 gene CTD PMID:29501571 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of MAPK8 mRNA CTD PMID:25716160 , PMID:29501571 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of MAPK8 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in decreased expression of MAPK8 mRNA CTD PMID:27188386 valproic acid increases phosphorylation ISO RGD:621506 6480464 Valproic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:23378038 verapamil multiple interactions ISO RGD:621506 6480464 Verapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15936777 vincaleukoblastine increases phosphorylation EXP 6480464 Vinblastine results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 vincaleukoblastine multiple interactions EXP 6480464 TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 vitamin E multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein] more ... CTD PMID:12684028 more ... vitamin E decreases expression EXP 6480464 Vitamin E results in decreased expression of MAPK8 mRNA CTD PMID:19244175 vitamin E increases activity EXP 6480464 Vitamin E results in increased activity of MAPK8 protein CTD PMID:11522656 vitamin E increases phosphorylation EXP 6480464 alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein CTD PMID:20686688 vorinostat multiple interactions EXP 6480464 [3-4-methylphenylsulfonyl-2-propenenitrile co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:12893773 more ... WIN 55212-2 increases phosphorylation EXP 6480464 Win 55212-2 results in increased phosphorylation of MAPK8 protein CTD PMID:20619260 withaferin A increases phosphorylation EXP 6480464 withaferin A results in increased phosphorylation of MAPK8 protein CTD PMID:21964475 wogonin multiple interactions ISO RGD:732272 6480464 wogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:23362215 wortmannin multiple interactions ISO RGD:732272 6480464 wortmannin inhibits the reaction [3-2-hydroxy-4-1 more ... CTD PMID:18950629 wortmannin multiple interactions ISO RGD:621506 6480464 Wortmannin inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased phosphorylation of MAPK8 protein] CTD PMID:10611455 wortmannin decreases phosphorylation ISO RGD:732272 6480464 wortmannin results in decreased phosphorylation of MAPK8 protein CTD PMID:18950629 Yessotoxin increases activity ISO RGD:732272 6480464 yessotoxin results in increased activity of MAPK8 protein CTD PMID:21945047 zearalenone increases phosphorylation ISO RGD:732272 6480464 Zearalenone results in increased phosphorylation of MAPK8 protein CTD PMID:21767629 zearalenone increases expression ISO RGD:732272 6480464 Zearalenone results in increased expression of MAPK8 mRNA CTD PMID:30717214 zidovudine increases phosphorylation EXP 6480464 Zidovudine results in increased phosphorylation of MAPK8 protein CTD PMID:27041070 zinc acetate multiple interactions ISO RGD:621506 6480464 [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 zinc atom increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc atom multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 zinc atom multiple interactions ISO RGD:621506 6480464 [[Taurine binds to Zinc] which co-treated with polyN-vinylpyrrolidine] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 , PMID:27501764 zinc atom multiple interactions EXP 6480464 [Clioquinol co-treated with Zinc] results in increased phosphorylation of MAPK8 protein CTD PMID:16648635 zinc dichloride multiple interactions ISO RGD:732272 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein] more ... CTD PMID:11306679 more ... zinc sulfate increases phosphorylation EXP 6480464 Zinc Sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc(0) increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc(0) multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 zinc(0) multiple interactions ISO RGD:621506 6480464 [[Taurine binds to Zinc] which co-treated with polyN-vinylpyrrolidine] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 , PMID:27501764 zinc(0) multiple interactions EXP 6480464 [Clioquinol co-treated with Zinc] results in increased phosphorylation of MAPK8 protein CTD PMID:16648635 zoledronic acid multiple interactions EXP 6480464 zoledronic acid promotes the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:17059425
