(+)-pilocarpine multiple interactions EXP 6480464 1 more ... CTD PMID:19927300 (+)-pilocarpine increases activity EXP 6480464 Pilocarpine results in increased activity of MAPK8 protein CTD PMID:19927300 (+)-taxifolin multiple interactions EXP 6480464 taxifolin inhibits the reaction [IFNG protein results in increased phosphorylation of MAPK8 protein] CTD PMID:12044887 (-)-anisomycin increases activity EXP 6480464 Anisomycin results in increased activity of MAPK8 protein CTD PMID:12902192 (-)-anisomycin multiple interactions EXP 6480464 Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15737997 , PMID:18241849 (-)-anisomycin increases phosphorylation ISO RGD:732272 6480464 Anisomycin results in increased phosphorylation of MAPK8 protein CTD PMID:15772366 , PMID:16038797 (-)-anisomycin multiple interactions ISO RGD:621506 6480464 Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15961565 (-)-anisomycin multiple interactions ISO RGD:732272 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3, 4-d)pyrimidine inhibits the reaction [Anisomycin results in increased phosphorylation of MAPK8 protein] CTD PMID:15772366 (-)-anisomycin increases phosphorylation EXP 6480464 Anisomycin results in increased phosphorylation of MAPK8 protein CTD PMID:12967334 , PMID:33075463 (-)-citrinin increases phosphorylation EXP 6480464 Citrinin results in increased phosphorylation of MAPK8 protein CTD PMID:19361540 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [[Paclitaxel co-treated with F2 protein] results in increased phosphorylation of MAPK8 protein], epigallocatechin gallate inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK8 protein] CTD PMID:19944065 , PMID:31252129 (-)-epigallocatechin 3-gallate increases activity EXP 6480464 epigallocatechin gallate results in increased activity of MAPK8 protein CTD PMID:15705601 (R)-lipoic acid multiple interactions ISO RGD:621506 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA CTD PMID:23830814 (R)-noradrenaline multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK8 protein] CTD PMID:17041759 (R)-noradrenaline increases phosphorylation ISO RGD:621506 6480464 Norepinephrine results in increased phosphorylation of MAPK8 protein CTD PMID:17041759 (R)-Salsolinol increases activity ISO RGD:621506 6480464 salsolinol results in increased activity of MAPK8 protein CTD PMID:11502874 (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK8 protein] more ... CTD PMID:12684028 more ... (R,R,R)-alpha-tocopherol increases phosphorylation EXP 6480464 alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein CTD PMID:20686688 (S)-colchicine increases phosphorylation EXP 6480464 Colchicine results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 (S)-colchicine multiple interactions EXP 6480464 TP53 protein affects the reaction [Colchicine results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 (S)-naringenin increases phosphorylation EXP 6480464 naringenin results in increased phosphorylation of MAPK8 protein CTD PMID:27838343 (S)-nicotine multiple interactions EXP 6480464 Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11592233 , PMID:20727180 (S)-nicotine increases activity ISO RGD:621506 6480464 Nicotine results in increased activity of MAPK8 protein CTD PMID:17021677 (S)-nicotine multiple interactions ISO RGD:621506 6480464 Nicotine promotes the reaction [MAPK8 protein results in increased phosphorylation of JUN protein] CTD PMID:17021677 (S)-nicotine increases expression ISO RGD:621506 6480464 Nicotine results in increased expression of MAPK8 mRNA CTD PMID:20426880 (S)-nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:20727180 (S)-nicotine increases phosphorylation ISO RGD:732272 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:21511693 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO RGD:732272 6480464 o more ... CTD PMID:18840457 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [o, p'-DDT results in increased phosphorylation of MAPK8 protein] CTD PMID:20678559 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases phosphorylation EXP 6480464 o, p'-DDT results in increased phosphorylation of MAPK8 protein CTD PMID:20678559 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose multiple interactions ISO RGD:732272 6480464 beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein], beta-penta-O-galloyl-glucose inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:30721698 1,2-dichloroethane decreases expression ISO RGD:732272 6480464 ethylene dichloride results in decreased expression of MAPK8 mRNA CTD PMID:28960355 1,2-dimethylhydrazine decreases expression ISO RGD:732272 6480464 1, 2-Dimethylhydrazine results in decreased expression of MAPK8 mRNA CTD PMID:22206623 1,3-dichloropropan-2-ol increases phosphorylation ISO RGD:621506 6480464 1, 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein CTD PMID:26143167 1,3-dichloropropan-2-ol multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [1, 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein] CTD PMID:29248572 1,3-dichloropropan-2-ol increases phosphorylation ISO RGD:732272 6480464 1, 3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein CTD PMID:29248572 1,3-Dinitropyrene increases phosphorylation ISO RGD:732272 6480464 1, 3-dinitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 1,4-phenylenediamine increases phosphorylation EXP 6480464 4-phenylenediamine results in increased phosphorylation of MAPK8 protein CTD PMID:23172806 1,8-cineole multiple interactions EXP 6480464 Eucalyptol inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased phosphorylation of MAPK8 protein] CTD PMID:23872422 1-chloro-2,4,6-trinitrobenzene increases phosphorylation ISO RGD:732272 6480464 Picryl Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:20381601 1-chloro-2,4-dinitrobenzene increases phosphorylation EXP 6480464 Dinitrochlorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:18495191 1-fluoro-2,4-dinitrobenzene increases phosphorylation EXP 6480464 Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 1-fluoro-2,4-dinitrobenzene multiple interactions EXP 6480464 Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 1-hydroxy-2-naphthoic acid multiple interactions ISO RGD:732272 6480464 1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein] CTD PMID:21667204 1-nitropyrene increases phosphorylation ISO RGD:732272 6480464 1-nitropyrene results in increased phosphorylation of MAPK8 protein CTD PMID:17240030 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of MAPK8 mRNA CTD PMID:16029874 17beta-estradiol multiple interactions ISO RGD:621506 6480464 Estradiol inhibits the reaction [Gentamicins results in increased activity of MAPK8 protein] CTD PMID:20074632 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone multiple interactions ISO RGD:732272 6480464 2' more ... CTD PMID:31029725 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone increases phosphorylation ISO RGD:732272 6480464 2' more ... CTD PMID:31029725 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:22543052 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 ERN1 protein affects the reaction [2 more ... CTD PMID:22543052 2,3',4,4',5-Pentachlorobiphenyl multiple interactions ISO RGD:621506 6480464 MAPK8 affects the reaction [2 more ... CTD PMID:26519956 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:732272 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects response to substance EXP 6480464 MAPK8 affects the susceptibility to Tetrachlorodibenzodioxin CTD PMID:9677421 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK8 protein CTD PMID:24469321 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732272 6480464 Tetrachlorodibenzodioxin affects the expression of MAPK8 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732272 6480464 Tetrachlorodibenzodioxin results in decreased expression of MAPK8 mRNA CTD PMID:19465110 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:732272 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK8 protein CTD PMID:20181658 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732272 6480464 MAPK8 protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of INSR protein] more ... CTD PMID:20181658 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 1 more ... CTD PMID:16619036 , PMID:24469321 2,3,7,8-tetrachlorodibenzodioxine increases response to substance EXP 6480464 MAPK8 results in increased susceptibility to Tetrachlorodibenzodioxin CTD PMID:9677421 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:621506 6480464 Trinitrobenzenesulfonic Acid results in increased expression of MAPK8 mRNA CTD PMID:23537331 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO RGD:621506 6480464 Verapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15936777 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine increases phosphorylation ISO RGD:621506 6480464 4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein CTD PMID:30790395 2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine multiple interactions ISO RGD:621506 6480464 gastrodin inhibits the reaction [4-iodo-2 more ... CTD PMID:30790395 2-acetamidofluorene multiple interactions ISO RGD:621506 6480464 2-Acetylaminofluorene affects the phosphorylation of and affects the activity of MAPK8 protein CTD PMID:17546627 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... 2-amino-2-deoxy-D-glucopyranose increases phosphorylation EXP 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 2-butoxyethanol decreases expression ISO RGD:732272 6480464 n-butoxyethanol results in decreased expression of MAPK8 mRNA CTD PMID:19812364 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO RGD:732272 6480464 6-methyl-2-(phenylethynyl)pyridine affects the reaction [[GOPC protein affects the susceptibility to Oxidopamine] which affects the phosphorylation of MAPK8 protein] more ... CTD PMID:29458170 , PMID:33571554 2-trans,6-trans-farnesyl diphosphate multiple interactions ISO RGD:732272 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 3',5'-cyclic GMP increases activity EXP 6480464 Cyclic GMP analog results in increased activity of MAPK8 protein CTD PMID:11051267 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions ISO RGD:621506 6480464 Puromycin Aminonucleoside binds to and results in increased activity of MAPK8 protein CTD PMID:15351692 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:621506 6480464 tetrabromobisphenol A results in decreased expression of MAPK8 mRNA CTD PMID:28970181 3,3',5,5'-tetrabromobisphenol A increases phosphorylation EXP 6480464 tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein CTD PMID:30766661 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein], diphenyleneiodonium inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein] CTD PMID:30766661 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [puag-haad results in increased expression of MAPK8 mRNA] CTD PMID:28780155 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione decreases expression EXP 6480464 bisindolylmaleimide I results in decreased expression of MAPK8 mRNA CTD PMID:28780155 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:732272 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein, beta-penta-O-galloyl-glucose inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:30721698 3-methylcholanthrene multiple interactions EXP 6480464 Methylcholanthrene results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16619036 3-O-Caffeoyl-1-O-methylquinic acid increases phosphorylation EXP 6480464 3-O-caffeoyl-1-methylquinic acid results in increased phosphorylation of MAPK8 protein CTD PMID:16631525 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamaldehyde results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15964311 3-phenylprop-2-enal multiple interactions ISO RGD:732272 6480464 cinnamaldehyde inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:17868967 3-phenylprop-2-enal increases phosphorylation EXP 6480464 cinnamaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:21469739 4,4'-diaminodiphenylmethane increases expression ISO RGD:732272 6480464 4, 4'-diaminodiphenylmethane results in increased expression of MAPK8 mRNA CTD PMID:18648102 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions ISO RGD:732272 6480464 4 more ... CTD PMID:19815690 4-hydroxynon-2-enal increases activity EXP 6480464 4-hydroxy-2-nonenal results in increased activity of MAPK8 protein CTD PMID:11488593 4-hydroxynon-2-enal increases phosphorylation EXP 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein CTD PMID:24825450 4-hydroxynon-2-enal affects response to substance ISO RGD:732272 6480464 MAPK8 protein affects the susceptibility to 4-hydroxy-2-nonenal CTD PMID:17263905 4-hydroxynon-2-enal increases phosphorylation ISO RGD:732272 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of MAPK8 protein CTD PMID:15064094 4-hydroxynon-2-enal increases activity ISO RGD:732272 6480464 4-hydroxy-2-nonenal results in increased activity of MAPK8 protein CTD PMID:17263905 4-hydroxynon-2-enal multiple interactions ISO RGD:732272 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15064094 , PMID:16322078 4-hydroxynon-2-enal multiple interactions EXP 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein, Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:12684028 4-hydroxyphenyl retinamide increases phosphorylation EXP 6480464 Fenretinide results in increased phosphorylation of MAPK8 protein CTD PMID:16407847 4-hydroxyphenyl retinamide increases activity EXP 6480464 Fenretinide results in increased activity of MAPK8 protein CTD PMID:16407847 4-hydroxyphenyl retinamide multiple interactions EXP 6480464 [IL24 protein co-treated with Fenretinide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:15580305 , PMID:16407847 4-nonylphenol increases phosphorylation ISO RGD:732272 6480464 4-nonylphenol analog results in increased phosphorylation of MAPK8 protein CTD PMID:27086933 4-phenylbutyric acid multiple interactions ISO RGD:621506 6480464 4-phenylbutyric acid inhibits the reaction [Cytotoxins results in increased phosphorylation of MAPK8 protein] CTD PMID:21147958 4-vinylcyclohexene dioxide increases expression ISO RGD:732272 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of MAPK8 mRNA CTD PMID:20829426 5-aza-2'-deoxycytidine decreases expression ISO RGD:732272 6480464 Decitabine results in decreased expression of MAPK8 mRNA CTD PMID:27915011 5-chloro-7-iodoquinolin-8-ol multiple interactions EXP 6480464 [Clioquinol co-treated with Copper] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:16648635 acetaldehyde increases phosphorylation EXP 6480464 Acetaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:19110045 acetaldehyde increases activity ISO RGD:621506 6480464 Acetaldehyde results in increased activity of MAPK8 protein CTD PMID:10733585 acetaldehyde multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:19110045 acetic acid multiple interactions ISO RGD:621506 6480464 Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:32045587 acetic acid increases phosphorylation ISO RGD:621506 6480464 Acetic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:32045587 acetylleucyl-leucyl-norleucinal increases phosphorylation ISO RGD:732272 6480464 acetylleucyl-leucyl-norleucinal results in increased phosphorylation of MAPK8 protein CTD PMID:15618349 Aciculatin multiple interactions ISO RGD:732272 6480464 aciculatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21548916 acrolein multiple interactions EXP 6480464 Phenylbutyrates inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein], RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:11329622 , PMID:18951912 acrolein increases phosphorylation EXP 6480464 Acrolein results in increased phosphorylation of MAPK8 protein CTD PMID:11329622 more ... acrolein multiple interactions ISO RGD:621506 6480464 SB 203580 promotes the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:12487375 acrolein increases phosphorylation ISO RGD:621506 6480464 [Acrolein results in increased phosphorylation of MAPK8 protein] which results in increased phosphorylation of JUN protein, Acrolein results in increased phosphorylation of MAPK8 protein CTD PMID:12487375 acrylamide increases phosphorylation ISO RGD:732272 6480464 Acrylamide results in increased phosphorylation of MAPK8 protein CTD PMID:25531190 , PMID:31081568 acrylamide increases expression ISO RGD:621506 6480464 Acrylamide results in increased expression of MAPK8 protein modified form CTD PMID:29426002 acrylamide multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:25531190 , PMID:31081568 ADP multiple interactions EXP 6480464 Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] CTD PMID:24466103 afimoxifene decreases response to substance EXP 6480464 MAPK8 results in decreased susceptibility to afimoxifene CTD PMID:21233418 aldehydo-D-glucosamine multiple interactions EXP 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... aldehydo-D-glucosamine increases phosphorylation EXP 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 aldehydo-D-glucose increases phosphorylation ISO RGD:621506 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 aldehydo-D-glucose multiple interactions EXP 6480464 Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:14505347 all-trans-retinoic acid multiple interactions ISO RGD:732272 6480464 pyrazolanthrone inhibits the reaction [Tretinoin results in increased activity of MAPK8 protein], SPAG9 protein promotes the reaction [Tretinoin results in increased phosphorylation of MAPK8 protein] CTD PMID:16619266 , PMID:21626648 all-trans-retinoic acid increases activity ISO RGD:732272 6480464 Tretinoin results in increased activity of MAPK8 protein CTD PMID:21626648 all-trans-retinoic acid decreases expression ISO RGD:732272 6480464 Tretinoin results in decreased expression of MAPK8 mRNA CTD PMID:22498432 all-trans-retinoic acid increases phosphorylation ISO RGD:732272 6480464 Tretinoin results in increased phosphorylation of MAPK8 protein CTD PMID:16619266 all-trans-retinoic acid decreases phosphorylation ISO RGD:732272 6480464 Tretinoin results in decreased phosphorylation of MAPK8 protein CTD PMID:16084493 alpha-Chaconine multiple interactions ISO RGD:732272 6480464 alpha-chaconine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:25913072 alpha-mangostin increases phosphorylation EXP 6480464 mangostin analog results in increased phosphorylation of MAPK8 protein CTD PMID:28722351 alvocidib multiple interactions EXP 6480464 [alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK8 protein, alvocidib promotes the reaction [Bortezomib results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15039284 , PMID:15634644 amidotrizoic acid increases phosphorylation EXP 6480464 Diatrizoate results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 amiloride multiple interactions ISO RGD:732272 6480464 Amiloride inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein] CTD PMID:19815690 amino acid multiple interactions ISO RGD:732272 6480464 Amino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein], H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in increased phosphorylation of MAPK8 protein]] CTD PMID:25309793 ammonium chloride affects expression ISO RGD:621506 6480464 Ammonium Chloride affects the expression of MAPK8 mRNA CTD PMID:16483693 ammonium chloride multiple interactions ISO RGD:621506 6480464 TLR5 gene mutant form inhibits the reaction [Ammonium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:30508503 ammonium chloride increases phosphorylation ISO RGD:621506 6480464 Ammonium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:30508503 amodiaquine multiple interactions EXP 6480464 [CYP2C8 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein, [CYP3A4 protein results in increased susceptibility to Amodiaquine] which results in increased phosphorylation of MAPK8 protein CTD PMID:31629065 amphetamine multiple interactions ISO RGD:621506 6480464 MAPK8 protein promotes the reaction [Amphetamine results in increased expression of GJA1 protein] CTD PMID:15194466 anethole multiple interactions EXP 6480464 anethole inhibits the reaction [TNF protein results in increased activity of MAPK8 protein] CTD PMID:10871845 aniline increases phosphorylation ISO RGD:621506 6480464 aniline results in increased phosphorylation of MAPK8 protein CTD PMID:16169568 , PMID:18420242 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:14610070 more ... anthra[1,9-cd]pyrazol-6(2H)-one increases expression ISO RGD:621506 6480464 pyrazolanthrone results in increased expression of MAPK8 protein CTD PMID:16046226 anthra[1,9-cd]pyrazol-6(2H)-one decreases phosphorylation ISO RGD:621506 6480464 pyrazolanthrone results in decreased phosphorylation of MAPK8 protein CTD PMID:22085843 , PMID:24833599 anthra[1,9-cd]pyrazol-6(2H)-one decreases activity EXP 6480464 pyrazolanthrone results in decreased activity of MAPK8 protein CTD PMID:12534346 , PMID:21112663 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16687388 more ... anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:732272 6480464 [pyrazolanthrone co-treated with 6 more ... CTD PMID:16374168 more ... Antimony trioxide multiple interactions EXP 6480464 [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein more ... CTD PMID:16112521 Antimony trioxide multiple interactions ISO RGD:732272 6480464 MAP2K4 protein affects the reaction [antimony trioxide results in increased activity of MAPK8 protein] CTD PMID:16112521 Antimony trioxide increases activity EXP 6480464 antimony trioxide results in increased activity of MAPK8 protein CTD PMID:16112521 ANTIMYCIN decreases phosphorylation ISO RGD:732272 6480464 antimycin results in decreased phosphorylation of MAPK8 protein CTD PMID:33290831 apigenin multiple interactions ISO RGD:621506 6480464 Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:25557508 apocynin multiple interactions ISO RGD:732272 6480464 acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:20354174 apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21391979 more ... arachidonic acid multiple interactions EXP 6480464 MAPK8 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein] more ... CTD PMID:19540902 aristolochic acid decreases expression EXP 6480464 aristolochic acid I results in decreased expression of MAPK8 mRNA CTD PMID:33212167 arsane multiple interactions EXP 6480464 Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:14633691 arsane multiple interactions ISO RGD:732272 6480464 [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein], [sodium arsenite results in increased abundance of Arsenic] which results in decreased phosphorylation of MAPK8 protein CTD PMID:33049506 arsane multiple interactions ISO RGD:621506 6480464 Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein more ... CTD PMID:11756236 , PMID:15210857 arsenic atom multiple interactions ISO RGD:621506 6480464 Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein more ... CTD PMID:11756236 , PMID:15210857 arsenic atom multiple interactions ISO RGD:732272 6480464 [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein], [sodium arsenite results in increased abundance of Arsenic] which results in decreased phosphorylation of MAPK8 protein CTD PMID:33049506 arsenic atom multiple interactions EXP 6480464 Arsenic results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:14633691 arsenic trichloride multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK8 protein] CTD PMID:22696236 arsenic trichloride increases phosphorylation EXP 6480464 arsenic trichloride results in increased phosphorylation of MAPK8 protein CTD PMID:22696236 , PMID:24434654 arsenic trichloride multiple interactions ISO RGD:732272 6480464 MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased activity of AKT1 protein], MAPK8 gene mutant form inhibits the reaction [arsenic trichloride results in increased phosphorylation of STAT3 protein] CTD PMID:22696236 arsenite(3-) decreases expression ISO RGD:732272 6480464 arsenite results in decreased expression of MAPK8 mRNA CTD PMID:18191166 arsenite(3-) increases phosphorylation ISO RGD:732272 6480464 arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:19808956 arsenite(3-) multiple interactions ISO RGD:732272 6480464 arsenite results in increased phosphorylation of and results in increased activity of MAPK8 protein, MAP3K8 protein affects the reaction [arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:15014438 , PMID:19808956 arsenous acid increases activity EXP 6480464 Arsenic Trioxide results in increased activity of MAPK8 protein CTD PMID:11304686 more ... arsenous acid increases phosphorylation ISO RGD:621506 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:21145380 more ... arsenous acid affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to Arsenic Trioxide CTD PMID:16818652 arsenous acid multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein], pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein] CTD PMID:21145380 , PMID:27174766 arsenous acid increases response to substance ISO RGD:732272 6480464 MAPK8 protein results in increased susceptibility to Arsenic Trioxide, MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:16818652 arsenous acid increases response to substance EXP 6480464 MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:20799280 arsenous acid multiple interactions EXP 6480464 [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:14610070 more ... arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MAPK8 protein CTD PMID:17374990 arsenous acid increases phosphorylation ISO RGD:732272 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:15688020 arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:18412143 more ... asbestos multiple interactions ISO RGD:732272 6480464 Asbestos results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:11280724 asiatic acid multiple interactions ISO RGD:732272 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein], asiatic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:30802477 atrazine increases expression EXP 6480464 Atrazine results in increased expression of MAPK8 mRNA CTD PMID:22378314 atrazine decreases expression ISO RGD:621506 6480464 Atrazine results in decreased expression of MAPK8 mRNA CTD PMID:31187311 atropine multiple interactions ISO RGD:621506 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 aureusidin increases phosphorylation ISO RGD:621506 6480464 aureusidin results in increased phosphorylation of MAPK8 protein CTD PMID:31790703 aureusidin multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK8 protein] CTD PMID:31790703 Azaspiracid multiple interactions ISO RGD:732272 6480464 4 more ... CTD PMID:19815690 bafilomycin A1 increases phosphorylation ISO RGD:732272 6480464 bafilomycin A1 results in increased phosphorylation of MAPK8 protein CTD PMID:31310755 baicalein multiple interactions EXP 6480464 baicalein results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:10718847 BAPTA multiple interactions EXP 6480464 1 more ... CTD PMID:19927300 bathocuproine disulfonic acid multiple interactions ISO RGD:621506 6480464 bathocuproine sulfonate inhibits the reaction [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] more ... CTD PMID:10941151 more ... benomyl increases expression ISO RGD:621506 6480464 Benomyl results in increased expression of MAPK8 mRNA CTD PMID:33930522 benzo[a]pyrene multiple interactions EXP 6480464 Nitrogen Oxides inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein], pyrazolanthrone inhibits the reaction [Benzo(a)pyrene results in increased expression of MAPK8 protein] CTD PMID:16041517 benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of MAPK8 promoter CTD PMID:27901495 benzo[a]pyrene increases phosphorylation ISO RGD:732272 6480464 Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein CTD PMID:18321868 benzo[a]pyrene multiple interactions ISO RGD:732272 6480464 Curcumin inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein] CTD PMID:18321868 benzo[a]pyrene increases phosphorylation EXP 6480464 Benzo(a)pyrene results in increased phosphorylation of MAPK8 protein CTD PMID:15698582 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of MAPK8 protein CTD PMID:16041517 benzo[a]pyrene diol epoxide I increases phosphorylation ISO RGD:732272 6480464 7 more ... CTD PMID:21501596 benzo[a]pyrene diol epoxide I increases phosphorylation EXP 6480464 7 more ... CTD PMID:20382639 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:732272 6480464 AG 1879 inhibits the reaction [7 more ... CTD PMID:21501596 Benzo[a]pyrene-7,8-diol increases phosphorylation EXP 6480464 benzo(a)pyrene 7, 8-dihydrodiol results in increased phosphorylation of MAPK8 protein CTD PMID:15698582 , PMID:22053912 benzyl isothiocyanate increases phosphorylation EXP 6480464 benzyl isothiocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:31587482 benzyl isothiocyanate multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [benzyl isothiocyanate results in increased phosphorylation of MAPK8 protein] CTD PMID:31587482 beta-D-glucosamine multiple interactions EXP 6480464 Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18080321 more ... beta-D-glucosamine increases phosphorylation EXP 6480464 Glucosamine analog results in increased phosphorylation of MAPK8 protein CTD PMID:18080321 beta-hexachlorocyclohexane multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein] CTD PMID:19760616 beta-hexachlorocyclohexane increases phosphorylation ISO RGD:621506 6480464 beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein CTD PMID:19760616 bicuculline multiple interactions ISO RGD:732272 6480464 [Bicuculline co-treated with Ethanol] results in increased expression of MAPK8 protein CTD PMID:29044621 bis(2-chloroethyl) sulfide increases phosphorylation ISO RGD:732272 6480464 Mustard Gas results in increased phosphorylation of MAPK8 protein CTD PMID:18200059 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:732272 6480464 Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein] CTD PMID:33484791 bis(2-ethylhexyl) phthalate increases phosphorylation EXP 6480464 Diethylhexyl Phthalate results in increased phosphorylation of MAPK8 protein CTD PMID:30944277 bis(2-ethylhexyl) phthalate increases phosphorylation ISO RGD:732272 6480464 Diethylhexyl Phthalate results in increased phosphorylation of MAPK8 protein CTD PMID:33484791 bisphenol A multiple interactions ISO RGD:621506 6480464 bisphenol A results in increased expression of and results in increased phosphorylation of MAPK8 protein CTD PMID:17322771 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MAPK8 mRNA CTD PMID:29275510 bisphenol A affects expression ISO RGD:621506 6480464 bisphenol A affects the expression of MAPK8 mRNA CTD PMID:25181051 bisphenol A increases phosphorylation ISO RGD:621506 6480464 bisphenol A results in increased phosphorylation of MAPK8 protein CTD PMID:20096755 , PMID:30496632 Bisphenol A diglycidyl ether multiple interactions ISO RGD:621506 6480464 2, 2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased phosphorylation of MAPK8 protein]] CTD PMID:27274199 bortezomib multiple interactions EXP 6480464 [[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:12893773 more ... bortezomib increases phosphorylation EXP 6480464 Bortezomib results in increased phosphorylation of MAPK8 protein CTD PMID:18559525 bufalin decreases activity EXP 6480464 bufalin results in decreased activity of MAPK8 protein CTD PMID:21922632 bupropion multiple interactions EXP 6480464 Bupropion results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:21354251 butanal decreases expression EXP 6480464 butyraldehyde results in decreased expression of MAPK8 mRNA CTD PMID:26079696 butylated hydroxyanisole multiple interactions EXP 6480464 Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK8 protein] CTD PMID:16407847 butylated hydroxyanisole multiple interactions ISO RGD:621506 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein] CTD PMID:18593901 butylated hydroxyanisole multiple interactions ISO RGD:732272 6480464 Butylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein] more ... CTD PMID:15989949 more ... butyric acid increases phosphorylation EXP 6480464 Butyric Acid results in increased phosphorylation of MAPK8 protein CTD PMID:28600122 butyric acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:28600122 cadmium atom multiple interactions ISO RGD:732272 6480464 1 more ... CTD PMID:15254339 more ... cadmium atom increases phosphorylation EXP 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:26187450 , PMID:26514923 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein more ... CTD PMID:26187450 more ... cadmium atom increases phosphorylation ISO RGD:732272 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:15212812 , PMID:15254339 cadmium atom decreases response to substance EXP 6480464 MAPK8 mutant form results in decreased susceptibility to Cadmium CTD PMID:10874022 cadmium atom increases phosphorylation ISO RGD:621506 6480464 Cadmium results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 cadmium atom affects response to substance ISO RGD:621506 6480464 MAPK8 protein affects the susceptibility to Cadmium CTD PMID:16516943 cadmium atom multiple interactions ISO RGD:621506 6480464 Cadmium results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16568437 cadmium dichloride multiple interactions ISO RGD:732272 6480464 1 more ... CTD PMID:11958953 more ... cadmium dichloride increases response to substance EXP 6480464 MAPK8 protein results in increased susceptibility to Cadmium Chloride CTD PMID:25374377 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of MAPK8 protein modified form CTD PMID:24419708 cadmium dichloride increases phosphorylation ISO RGD:621506 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:18021293 more ... cadmium dichloride increases phosphorylation ISO RGD:732272 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:11958953 , PMID:18348256 cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:10874044 more ... cadmium dichloride increases activity ISO RGD:621506 6480464 Cadmium Chloride results in increased activity of MAPK8 protein CTD PMID:10637132 cadmium dichloride multiple interactions EXP 6480464 1 more ... CTD PMID:21219922 more ... cadmium dichloride multiple interactions ISO RGD:621506 6480464 1 more ... CTD PMID:15618353 more ... cadmium selenide multiple interactions EXP 6480464 [cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK8 mRNA CTD PMID:22342292 cadmium sulfate multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein], cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:14687664 cadmium sulfate multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein], Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:22767315 cadmium sulfate increases phosphorylation ISO RGD:621506 6480464 cadmium sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:22767315 Calcimycin multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA, fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA] CTD PMID:21331654 calcipotriol decreases response to substance ISO RGD:732272 6480464 MAPK8 gene mutant form results in decreased susceptibility to calcipotriene CTD PMID:24046278 calcitriol multiple interactions EXP 6480464 Calcitriol results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:12761878 camptothecin increases phosphorylation EXP 6480464 Camptothecin results in increased phosphorylation of MAPK8 protein CTD PMID:30885713 , PMID:31255635 camptothecin multiple interactions EXP 6480464 MAPK8 protein affects the reaction [Camptothecin results in increased activity of SP1 protein] more ... CTD PMID:30885713 candesartan multiple interactions ISO RGD:732272 6480464 candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:20562518 cantharidic acid increases phosphorylation EXP 6480464 cantharidic acid results in increased phosphorylation of MAPK8 protein CTD PMID:29345422 , PMID:31916385 capsaicin multiple interactions EXP 6480464 5-7-oxo-zeaenol inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:17292493 more ... capsaicin increases activity EXP 6480464 Capsaicin results in increased activity of MAPK8 protein CTD PMID:12478662 more ... capsaicin increases phosphorylation EXP 6480464 Capsaicin results in increased phosphorylation of MAPK8 protein CTD PMID:20619260 capsazepine multiple interactions EXP 6480464 capsazepine inhibits the reaction [Capsaicin results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:22171160 carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of MAPK8 mRNA CTD PMID:24752500 carbon nanotube increases phosphorylation EXP 6480464 Nanotubes, Carbon results in increased phosphorylation of MAPK8 protein CTD PMID:32493873 carnosic acid multiple interactions ISO RGD:621506 6480464 salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:25446857 carnosic acid multiple interactions ISO RGD:732272 6480464 salvin inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:29854073 carnosine multiple interactions ISO RGD:732272 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein], Carnosine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:30802477 celecoxib multiple interactions EXP 6480464 Celecoxib inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein] CTD PMID:16442704 celecoxib multiple interactions ISO RGD:732272 6480464 Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein] CTD PMID:32416088 chalcone multiple interactions ISO RGD:732272 6480464 Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:22155221 chenodeoxycholic acid multiple interactions ISO RGD:732272 6480464 Chenodeoxycholic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein], Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 chlordecone decreases expression ISO RGD:732272 6480464 Chlordecone results in decreased expression of MAPK8 mRNA CTD PMID:29980752 chloroprene increases expression ISO RGD:621506 6480464 Chloroprene results in increased expression of MAPK8 mRNA CTD PMID:23125180 chloroquine multiple interactions ISO RGD:732272 6480464 Chloroquine inhibits the reaction [lipopolysaccharide more ... CTD PMID:22341560 , PMID:28134560 chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]], Chloroquine promotes the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 chlorpromazine multiple interactions ISO RGD:732272 6480464 [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:23238562 chlorpyrifos increases phosphorylation ISO RGD:621506 6480464 Chlorpyrifos results in increased phosphorylation of MAPK8 protein CTD PMID:22714038 cholate increases phosphorylation ISO RGD:732272 6480464 Cholates results in increased phosphorylation of MAPK8 protein CTD PMID:15750181 choline multiple interactions ISO RGD:732272 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein, Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 chromium atom multiple interactions ISO RGD:732272 6480464 Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:21134603 chromium(6+) multiple interactions ISO RGD:732272 6480464 [Arsenates co-treated with chromium hexavalent ion] results in increased expression of MAPK8 protein more ... CTD PMID:19654923 , PMID:19895865 chromium(6+) increases activity EXP 6480464 chromium hexavalent ion results in increased activity of MAPK8 protein CTD PMID:12902192 chromium(6+) multiple interactions EXP 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:12902192 chromium(6+) increases phosphorylation ISO RGD:732272 6480464 chromium hexavalent ion results in increased phosphorylation of MAPK8 protein CTD PMID:19654923 , PMID:19895865 chromium(6+) increases expression ISO RGD:732272 6480464 chromium hexavalent ion results in increased expression of MAPK8 protein CTD PMID:19895865 chromium(6+) increases phosphorylation EXP 6480464 chromium hexavalent ion results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 chrysophanol affects phosphorylation EXP 6480464 chrysophanic acid affects the phosphorylation of MAPK8 protein CTD PMID:30300626 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with 2 more ... CTD PMID:11592233 more ... cisplatin increases phosphorylation EXP 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:30550853 , PMID:32238696 cisplatin multiple interactions ISO RGD:732272 6480464 hesperetin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:31153982 cisplatin increases phosphorylation ISO RGD:732272 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:31153982 cisplatin increases expression ISO RGD:621506 6480464 Cisplatin results in increased expression of MAPK8 protein modified form CTD PMID:26739623 cisplatin multiple interactions ISO RGD:621506 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form], N-Acetylcysteinamide inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:15147517 , PMID:26739623 cisplatin increases phosphorylation ISO RGD:621506 6480464 Cisplatin results in increased phosphorylation of MAPK8 protein CTD PMID:15147517 cisplatin increases expression ISO RGD:732272 6480464 Cisplatin results in increased expression of MAPK8 mRNA CTD PMID:20883750 cobalt dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein], ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:24386346 cobalt dichloride multiple interactions ISO RGD:621506 6480464 iodopravadoline inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein], Protein Kinase Inhibitors inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21925238 , PMID:31472278 cobalt dichloride increases phosphorylation ISO RGD:621506 6480464 cobaltous chloride results in increased phosphorylation of MAPK8 protein CTD PMID:21925238 more ... cobalt dichloride increases phosphorylation EXP 6480464 cobaltous chloride results in increased phosphorylation of MAPK8 protein CTD PMID:19101624 , PMID:24386346 cocaine multiple interactions ISO RGD:732272 6480464 acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:20354174 copper atom multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of MAPK8 mRNA more ... CTD PMID:16648635 more ... copper atom multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:24690739 , PMID:30768131 copper atom multiple interactions ISO RGD:621506 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:10941151 more ... copper(0) multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of MAPK8 mRNA more ... CTD PMID:16648635 more ... copper(0) multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:24690739 , PMID:30768131 copper(0) multiple interactions ISO RGD:621506 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:10941151 more ... copper(II) chloride multiple interactions ISO RGD:621506 6480464 [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein more ... CTD PMID:11239917 , PMID:20920558 copper(II) chloride multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 copper(II) sulfate increases phosphorylation ISO RGD:732272 6480464 Copper Sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:33744278 copper(II) sulfate increases expression ISO RGD:732272 6480464 Copper Sulfate results in increased expression of MAPK8 mRNA CTD PMID:33744278 crocidolite asbestos increases expression ISO RGD:732272 6480464 Asbestos, Crocidolite results in increased expression of MAPK8 mRNA CTD PMID:19446018 crocidolite asbestos increases expression EXP 6480464 Asbestos, Crocidolite results in increased expression of MAPK8 mRNA CTD PMID:25757056 Cuprizon decreases expression ISO RGD:621506 6480464 Cuprizone results in decreased expression of MAPK8 mRNA CTD PMID:26577399 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK8 mRNA] more ... CTD PMID:18316600 more ... curcumin increases phosphorylation EXP 150429751 Curcumin increases phosphorylation of MAPK8 protein in uterine cervix RGD curcumin decreases phosphorylation ISO RGD:621506 6480464 Curcumin results in decreased phosphorylation of MAPK8 protein CTD PMID:18332871 curcumin multiple interactions ISO RGD:621506 6480464 Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11981161 more ... curcumin multiple interactions ISO RGD:732272 6480464 Curcumin inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16678799 more ... curcumin increases expression EXP 6480464 Curcumin results in increased expression of MAPK8 mRNA CTD PMID:16101141 curcumin increases phosphorylation EXP 6480464 Curcumin results in increased phosphorylation of MAPK8 protein CTD PMID:18316600 cyclophosphamide increases phosphorylation ISO RGD:732272 6480464 Cyclophosphamide results in increased phosphorylation of MAPK8 protein CTD PMID:19696094 cyclophosphamide multiple interactions ISO RGD:621506 6480464 Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein, NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19996110 cyclophosphamide multiple interactions ISO RGD:732272 6480464 GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:19696094 cyclosporin A increases expression ISO RGD:621506 6480464 Cyclosporine results in increased expression of MAPK8 protein CTD PMID:10617104 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of MAPK8 mRNA CTD PMID:25562108 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of MAPK8 mRNA CTD PMID:27704156 cypermethrin multiple interactions ISO RGD:732272 6480464 [[[cypermethrin results in decreased expression of MIR155 mRNA] which results in increased expression of BCL6 mRNA] which results in decreased expression of MAP2K4 protein] which results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:29471534 D-glucose increases phosphorylation ISO RGD:621506 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 D-glucose multiple interactions EXP 6480464 Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:14505347 D-mannitol multiple interactions EXP 6480464 Mannitol promotes the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein] CTD PMID:10910949 DDT decreases phosphorylation EXP 6480464 DDT results in decreased phosphorylation of MAPK8 protein CTD PMID:14604893 decabromodiphenyl ether affects expression EXP 6480464 decabromobiphenyl ether affects the expression of MAPK8 mRNA CTD PMID:24834073 delphinidin multiple interactions EXP 6480464 delphinidin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15740068 deoxynivalenol decreases activity EXP 6480464 deoxynivalenol results in decreased activity of MAPK8 protein CTD PMID:20708668 deoxynivalenol increases phosphorylation ISO RGD:732272 6480464 deoxynivalenol results in increased phosphorylation of MAPK8 protein CTD PMID:12377986 more ... deoxynivalenol multiple interactions ISO RGD:732272 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:14644621 more ... deoxynivalenol multiple interactions EXP 6480464 [deoxynivalenol results in increased expression of DUSP1 protein] which results in decreased activity of MAPK8 protein, deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:18485432 more ... desferrioxamine B increases phosphorylation EXP 6480464 Deferoxamine results in increased phosphorylation of MAPK8 protein CTD PMID:20368581 desferrioxamine B multiple interactions EXP 6480464 Deferoxamine inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein] CTD PMID:20206247 desipramine multiple interactions EXP 6480464 1 more ... CTD PMID:18606486 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein], Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]] CTD PMID:10807665 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of MAPK8 mRNA CTD PMID:31181236 dexamethasone affects phosphorylation ISO RGD:621506 6480464 Dexamethasone affects the phosphorylation of MAPK8 protein CTD PMID:18234956 dexamethasone multiple interactions ISO RGD:732272 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10874129 more ... diallyl disulfide increases phosphorylation EXP 6480464 diallyl disulfide results in increased phosphorylation of MAPK8 protein CTD PMID:14522920 diallyl disulfide multiple interactions EXP 6480464 diallyl disulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17647244 Diallyl sulfide multiple interactions EXP 6480464 allyl sulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17647244 diarsenic trioxide multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein], pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein] CTD PMID:21145380 , PMID:27174766 diarsenic trioxide increases phosphorylation ISO RGD:732272 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:15688020 diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:18412143 more ... diarsenic trioxide increases activity EXP 6480464 Arsenic Trioxide results in increased activity of MAPK8 protein CTD PMID:11304686 more ... diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of MAPK8 protein CTD PMID:17374990 diarsenic trioxide multiple interactions EXP 6480464 [IL24 protein co-treated with Arsenic Trioxide] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:14610070 more ... diarsenic trioxide affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to Arsenic Trioxide CTD PMID:16818652 diarsenic trioxide increases phosphorylation ISO RGD:621506 6480464 Arsenic Trioxide results in increased phosphorylation of MAPK8 protein CTD PMID:21145380 more ... diarsenic trioxide increases response to substance ISO RGD:732272 6480464 MAPK8 protein results in increased susceptibility to Arsenic Trioxide, MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:16818652 diarsenic trioxide increases response to substance EXP 6480464 MAPK8 results in increased susceptibility to Arsenic Trioxide CTD PMID:20799280 diazepam multiple interactions ISO RGD:621506 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 diazinon increases expression ISO RGD:621506 6480464 Diazinon results in increased expression of MAPK8 mRNA CTD PMID:29108742 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21391979 more ... dibutyl phthalate decreases expression ISO RGD:621506 6480464 Dibutyl Phthalate results in decreased expression of MAPK8 mRNA CTD PMID:21266533 diclofenac affects expression EXP 6480464 Diclofenac affects the expression of MAPK8 mRNA CTD PMID:24752500 dicoumarol multiple interactions EXP 6480464 Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein], Dicumarol inhibits the reaction [Arsenic Trioxide results in increased activity of MAPK8 protein] CTD PMID:14701702 , PMID:24466103 dicrotophos decreases expression EXP 6480464 dicrotophos results in decreased expression of MAPK8 mRNA CTD PMID:28302478 Dictamnine multiple interactions EXP 6480464 dictamnine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:30266538 diethylstilbestrol multiple interactions ISO RGD:732272 6480464 Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15171707 diltiazem decreases activity ISO RGD:621506 6480464 Diltiazem results in decreased activity of MAPK8 protein CTD PMID:11937779 dimethylarsinic acid increases expression ISO RGD:732272 6480464 Cacodylic Acid results in increased expression of MAPK8 mRNA CTD PMID:17441966 dimethylarsinic acid decreases expression ISO RGD:621506 6480464 Cacodylic Acid results in decreased expression of MAPK8 mRNA CTD PMID:17481689 Dinitramine increases phosphorylation ISO RGD:732272 6480464 dinitramine results in increased phosphorylation of MAPK8 protein CTD PMID:33288293 dinophysistoxin 1 increases expression EXP 6480464 dinophysistoxin 1 results in increased expression of MAPK8 mRNA CTD PMID:28939011 dioscin increases expression EXP 6480464 dioscin results in increased expression of MAPK8 mRNA CTD PMID:29990575 dioxygen multiple interactions EXP 6480464 dictamnine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10780954 more ... dioxygen increases activity EXP 6480464 Oxygen deficiency results in increased activity of MAPK8 protein CTD PMID:10780954 , PMID:13679210 dioxygen increases phosphorylation ISO RGD:621506 6480464 Oxygen results in increased phosphorylation of MAPK8 protein CTD PMID:20812253 dioxygen multiple interactions ISO RGD:621506 6480464 2 more ... CTD PMID:12892836 , PMID:27274199 dioxygen increases activity ISO RGD:621506 6480464 Oxygen deficiency results in increased activity of MAPK8 protein CTD PMID:12892836 dioxygen increases phosphorylation EXP 6480464 Oxygen deficiency results in increased phosphorylation of MAPK8 protein CTD PMID:19196431 , PMID:30266538 diphenhydramine increases activity EXP 6480464 Diphenhydramine results in increased activity of MAPK8 CTD PMID:17390763 dipyridamole increases activity EXP 6480464 Dipyridamole results in increased activity of MAPK8 protein CTD PMID:11051267 disodium selenite multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:10644709 , PMID:18728404 disodium selenite multiple interactions ISO RGD:732272 6480464 Sodium Selenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK8 protein], Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein] CTD PMID:18481333 , PMID:26522834 disodium selenite decreases expression EXP 6480464 Sodium Selenite results in decreased expression of MAPK8 mRNA CTD PMID:18175754 disodium selenite decreases activity EXP 6480464 Sodium Selenite results in decreased activity of MAPK8 protein CTD PMID:10644709 disulfiram multiple interactions ISO RGD:621506 6480464 [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein, bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein] CTD PMID:11239917 disulfiram multiple interactions EXP 6480464 [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein CTD PMID:24690739 disulfiram multiple interactions ISO RGD:732272 6480464 [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein CTD PMID:24690739 donepezil hydrochloride multiple interactions ISO RGD:621506 6480464 Donepezil inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of MAPK8 protein] CTD PMID:19345205 dopamine multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein], Glutathione inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:17481858 dopamine increases phosphorylation ISO RGD:732272 6480464 Dopamine results in increased phosphorylation of MAPK8 protein CTD PMID:17481858 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 dorsomorphin multiple interactions ISO RGD:621506 6480464 dorsomorphin inhibits the reaction [Resveratrol results in decreased expression of MAPK8 protein modified form] CTD PMID:27093858 doxorubicin multiple interactions EXP 6480464 [DLJ14 compound co-treated with Doxorubicin] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:15494689 more ... doxorubicin increases phosphorylation ISO RGD:621506 6480464 Doxorubicin results in increased phosphorylation of MAPK8 protein CTD PMID:15623433 more ... doxorubicin increases expression ISO RGD:621506 6480464 Doxorubicin results in increased expression of MAPK8 mRNA CTD PMID:26335259 doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of MAPK8 protein CTD PMID:15917298 more ... doxorubicin multiple interactions ISO RGD:621506 6480464 [Taurine binds to Zinc] inhibits the reaction [Doxorubicin results in increased expression of MAPK8 mRNA] more ... CTD PMID:18346979 , PMID:26335259 doxorubicin increases response to substance EXP 6480464 MAPK8 protein results in increased susceptibility to Doxorubicin CTD PMID:15917298 doxorubicin increases activity EXP 6480464 Doxorubicin results in increased activity of MAPK8 protein CTD PMID:15880572 doxorubicin affects activity EXP 6480464 Doxorubicin affects the activity of MAPK8 protein CTD PMID:15870702 edaravone increases phosphorylation EXP 6480464 Edaravone results in increased phosphorylation of MAPK8 protein CTD PMID:19954754 edaravone decreases phosphorylation ISO RGD:732272 6480464 Edaravone results in decreased phosphorylation of MAPK8 protein CTD PMID:15824197 efavirenz multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein], Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein] CTD PMID:21958719 efavirenz increases phosphorylation EXP 6480464 efavirenz metabolite results in increased phosphorylation of MAPK8 protein, efavirenz results in increased phosphorylation of MAPK8 protein CTD PMID:21958719 elemental selenium decreases phosphorylation ISO RGD:732272 6480464 Selenium results in decreased phosphorylation of MAPK8 protein CTD PMID:17997286 elemental selenium multiple interactions EXP 6480464 Selenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:26187450 elemental selenium decreases expression ISO RGD:732272 6480464 Selenium results in decreased expression of MAPK8 mRNA CTD PMID:28810182 ellagic acid multiple interactions EXP 6480464 [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein CTD PMID:15735102 emetine multiple interactions ISO RGD:732272 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3, 4-d)pyrimidine inhibits the reaction [Emetine results in increased phosphorylation of MAPK8 protein] CTD PMID:15772366 emetine increases phosphorylation ISO RGD:732272 6480464 Emetine results in increased phosphorylation of MAPK8 protein CTD PMID:15772366 enilconazole increases expression EXP 6480464 enilconazole results in increased expression of MAPK8 mRNA CTD PMID:32201337 entinostat multiple interactions EXP 6480464 [3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with entinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15964800 entinostat decreases expression EXP 6480464 entinostat results in decreased expression of MAPK8 mRNA CTD PMID:27188386 erastin multiple interactions ISO RGD:732272 6480464 GW 506033X inhibits the reaction [erastin results in increased phosphorylation of MAPK8 protein] CTD PMID:30817950 erastin increases phosphorylation ISO RGD:732272 6480464 erastin results in increased phosphorylation of MAPK8 protein CTD PMID:30817950 eriodictyol multiple interactions ISO RGD:732272 6480464 eriodictyol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21544733 esculetin multiple interactions EXP 6480464 [esculetin co-treated with Paclitaxel] results in increased expression of MAPK8 protein CTD PMID:16051289 esculetin increases phosphorylation EXP 6480464 esculetin results in increased phosphorylation of MAPK8 protein CTD PMID:19786087 esculetin increases expression EXP 6480464 esculetin results in increased expression of MAPK8 protein CTD PMID:16051289 Estragole increases phosphorylation ISO RGD:621506 6480464 estragole results in increased phosphorylation of MAPK8 protein CTD PMID:29054680 etacrynic acid decreases expression EXP 6480464 Ethacrynic Acid results in decreased expression of MAPK8 protein CTD PMID:14556662 ethanol multiple interactions ISO RGD:621506 6480464 Polysaccharides inhibits the reaction [Ethanol results in increased phosphorylation of MAPK8 protein] CTD PMID:19735724 ethanol multiple interactions EXP 6480464 MAPK8 promotes the reaction [Ethanol results in increased expression of and results in increased activity of RUNX2 protein] CTD PMID:32198086 ethanol multiple interactions ISO RGD:732272 6480464 [Bicuculline co-treated with Ethanol] results in increased expression of MAPK8 protein more ... CTD PMID:29044621 ethanol increases phosphorylation EXP 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:28062356 ethanol increases phosphorylation ISO RGD:732272 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:28119953 , PMID:29044621 ethanol increases phosphorylation ISO RGD:621506 6480464 Ethanol results in increased phosphorylation of MAPK8 protein CTD PMID:19735724 Ethyl pyruvate multiple interactions ISO RGD:621506 6480464 ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein] CTD PMID:21818760 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:621506 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein], Egtazic Acid inhibits the reaction [Tetracaine results in increased phosphorylation of MAPK8 protein] CTD PMID:11981161 , PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:732272 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein], Egtazic Acid inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:15254339 , PMID:21544200 Evodiamine multiple interactions EXP 6480464 1 more ... CTD PMID:23774672 Evodiamine increases expression EXP 6480464 evodiamine results in increased expression of MAPK8 protein modified form CTD PMID:23774672 farnesyl diphosphate multiple interactions ISO RGD:732272 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]] CTD PMID:18310456 fenvalerate multiple interactions EXP 6480464 fenvalerate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein] CTD PMID:28949029 ferrosoferric oxide multiple interactions EXP 6480464 [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 ferulic acid decreases activity ISO RGD:621506 6480464 ferulic acid results in decreased activity of MAPK8 protein CTD PMID:15363954 ferulic acid multiple interactions ISO RGD:732272 6480464 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21291945 flubendazole increases activity EXP 6480464 flubendazole results in increased activity of MAPK8 protein CTD PMID:32652169 flufenoxuron increases phosphorylation ISO RGD:732272 6480464 flufenoxuron results in increased phosphorylation of MAPK8 protein CTD PMID:33771252 flufenoxuron multiple interactions ISO RGD:732272 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [flufenoxuron results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:33771252 fluorescein 5-isothiocyanate increases phosphorylation EXP 6480464 Fluorescein-5-isothiocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 fluorescein 5-isothiocyanate multiple interactions EXP 6480464 Fluorescein-5-isothiocyanate inhibits the reaction [Dinitrofluorobenzene results in increased phosphorylation of MAPK8 protein], Fluorescein-5-isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 fluoxetine decreases expression ISO RGD:621506 6480464 Fluoxetine results in decreased expression of MAPK8 mRNA CTD PMID:20924750 flutamide increases expression ISO RGD:621506 6480464 Flutamide results in increased expression of MAPK8 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:732272 6480464 [pyrazolanthrone co-treated with 6 more ... CTD PMID:21528358 more ... folic acid decreases expression ISO RGD:732272 6480464 Folic Acid results in decreased expression of MAPK8 mRNA CTD PMID:25629700 folic acid increases phosphorylation ISO RGD:732272 6480464 Folic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:31447676 fomepizole multiple interactions ISO RGD:732272 6480464 Fomepizole inhibits the reaction [Acetaminophen results in increased phosphorylation of and affects the localization of MAPK8 protein] CTD PMID:29739258 , PMID:30903181 fomepizole affects binding ISO RGD:732272 6480464 Fomepizole binds to MAPK8 protein CTD PMID:30903181 formononetin multiple interactions EXP 6480464 formononetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:34077701 formoterol fumarate multiple interactions ISO RGD:621506 6480464 [Formoterol Fumarate co-treated with desisobutyrylciclesonide] inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein], Formoterol Fumarate inhibits the reaction [dinitrophenyl-bovine serum albumin results in increased phosphorylation of MAPK8 protein] CTD PMID:26003274 fructose increases expression ISO RGD:621506 6480464 Fructose results in increased expression of MAPK8 protein CTD PMID:29430716 fructose multiple interactions ISO RGD:621506 6480464 imoxin inhibits the reaction [Fructose results in increased expression of MAPK8 protein] CTD PMID:29430716 gallic acid multiple interactions EXP 6480464 Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:21420233 gamma-aminobutyric acid multiple interactions ISO RGD:732272 6480464 gamma-Aminobutyric Acid inhibits the reaction [Ethanol results in increased expression of MAPK8 protein] CTD PMID:29044621 gamma-hexachlorocyclohexane multiple interactions ISO RGD:621506 6480464 Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:23927878 Gastrodin multiple interactions ISO RGD:621506 6480464 gastrodin inhibits the reaction [4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein] CTD PMID:30790395 gefitinib increases phosphorylation EXP 6480464 gefitinib results in increased phosphorylation of MAPK8 protein CTD PMID:20846305 Geniposide pentaacetate multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein] CTD PMID:17651887 Geniposide pentaacetate increases phosphorylation ISO RGD:621506 6480464 pentaacetyl geniposide results in increased phosphorylation of MAPK8 protein CTD PMID:17651887 gentamycin multiple interactions ISO RGD:621506 6480464 CAT protein inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:15936777 more ... gentamycin increases activity ISO RGD:621506 6480464 Gentamicins results in increased activity of MAPK8 protein CTD PMID:20074632 gentamycin increases phosphorylation ISO RGD:621506 6480464 Gentamicins results in increased phosphorylation of MAPK8 protein CTD PMID:16401625 ginkgolide B multiple interactions EXP 6480464 ginkgolide B inhibits the reaction [APP protein results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19464278 ginsenoside Rg1 multiple interactions EXP 6480464 ginsenoside Rg1 inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:24386346 gliclazide multiple interactions ISO RGD:621506 6480464 Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:32045587 gliotoxin multiple interactions ISO RGD:621506 6480464 Gliotoxin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17466404 glucose increases phosphorylation ISO RGD:621506 6480464 Glucose results in increased phosphorylation of MAPK8 protein CTD PMID:19861503 glucose multiple interactions EXP 6480464 Glucose deficiency results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:14505347 glutathione multiple interactions EXP 6480464 Glutathione deficiency promotes the reaction [antimony trioxide results in increased activity of MAPK8 protein] CTD PMID:16112521 glutathione multiple interactions ISO RGD:621506 6480464 Glutathione inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:22767315 glutathione multiple interactions ISO RGD:732272 6480464 Glutathione inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein], Glutathione inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:17481858 , PMID:20423716 glyphosate increases expression EXP 6480464 glyphosate results in increased expression of MAPK8 mRNA CTD PMID:31874349 Goe 6976 multiple interactions EXP 6480464 Go 6976 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:28087840 guggulsterone increases activity EXP 6480464 pregna-4 more ... CTD PMID:17475222 GW 4064 multiple interactions EXP 6480464 GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:25496033 GW 4064 increases expression ISO RGD:732272 6480464 GW 4064 results in increased expression of MAPK8 mRNA CTD PMID:26655953 GW 4064 multiple interactions ISO RGD:732272 6480464 GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein], GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 haloperidol increases phosphorylation ISO RGD:621506 6480464 Haloperidol results in increased phosphorylation of MAPK8 protein CTD PMID:17092607 hemin multiple interactions ISO RGD:621506 6480464 Hemin promotes the reaction [Paraquat results in increased phosphorylation of MAPK8 protein] CTD PMID:19080378 hesperetin multiple interactions EXP 6480464 [Cisplatin co-treated with hesperetin] results in decreased phosphorylation of MAPK8 protein CTD PMID:31153982 hesperetin multiple interactions ISO RGD:621506 6480464 hesperetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:19222219 hesperetin multiple interactions ISO RGD:732272 6480464 hesperetin inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein] CTD PMID:31153982 hesperidin multiple interactions EXP 6480464 Hesperidin inhibits the reaction [Acetaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:19110045 hexachlorobenzene increases phosphorylation ISO RGD:621506 6480464 Hexachlorobenzene results in increased phosphorylation of MAPK8 protein CTD PMID:23708402 hexadecanoic acid multiple interactions EXP 6480464 Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:21745629 hexadecanoic acid increases expression ISO RGD:621506 6480464 Palmitic Acid results in increased expression of MAPK8 mRNA CTD PMID:30259999 hexadecanoic acid multiple interactions ISO RGD:621506 6480464 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of MAPK8 protein]] more ... CTD PMID:25109277 , PMID:30259999 hexadecanoic acid increases phosphorylation ISO RGD:732272 6480464 Palmitic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:21134603 hexadecanoic acid multiple interactions ISO RGD:732272 6480464 Chromium inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:21134603 hexadecanoic acid increases phosphorylation EXP 6480464 Palmitic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:21745629 hexamethylene diisocyanate increases phosphorylation EXP 6480464 1, 6-hexamethylene diisocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 hexamethylene diisocyanate multiple interactions EXP 6480464 1, 6-hexamethylene diisocyanate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 histamine multiple interactions ISO RGD:621506 6480464 Histamine inhibits the reaction [decamethrin results in decreased nitrosation of MAPK8 protein] CTD PMID:25299849 homocysteine increases phosphorylation EXP 6480464 Homocysteine results in increased phosphorylation of MAPK8 protein CTD PMID:25888188 homocysteine multiple interactions EXP 6480464 fulvic acid inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK8 protein] CTD PMID:25888188 hydrogen peroxide multiple interactions EXP 6480464 2''-galloylhyperin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10910949 more ... hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of MAPK8 mRNA CTD PMID:31521693 hydrogen peroxide increases phosphorylation ISO RGD:621506 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:16284289 more ... hydrogen peroxide increases phosphorylation ISO RGD:732272 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:15064094 more ... hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein CTD PMID:10910949 more ... hydrogen peroxide increases activity EXP 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:12215205 , PMID:12902192 hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of MAPK8 protein CTD PMID:21179406 hydrogen peroxide increases activity ISO RGD:732272 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:10843682 more ... hydrogen peroxide increases activity ISO RGD:621506 6480464 Hydrogen Peroxide results in increased activity of MAPK8 protein CTD PMID:15574683 hydrogen peroxide multiple interactions ISO RGD:621506 6480464 2-(4-((dimethylamino)methyl)benzylidene)-5 more ... CTD PMID:11562448 more ... hydrogen peroxide multiple interactions ISO RGD:732272 6480464 Chenodeoxycholic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10843682 more ... hydroquinone O-beta-D-glucopyranoside decreases expression EXP 6480464 Arbutin results in decreased expression of MAPK8 mRNA CTD PMID:17103032 hydroxyurea decreases phosphorylation ISO RGD:621506 6480464 Hydroxyurea results in decreased phosphorylation of MAPK8 protein CTD PMID:15557822 hypochlorous acid multiple interactions EXP 6480464 Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:18156441 icatibant multiple interactions ISO RGD:621506 6480464 icatibant inhibits the reaction [KLK1 protein inhibits the reaction [Gentamicins results in increased phosphorylation of MAPK8 protein]] CTD PMID:16401625 ifosfamide multiple interactions ISO RGD:621506 6480464 morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] CTD PMID:31722249 ifosfamide increases activity ISO RGD:621506 6480464 Ifosfamide results in increased activity of MAPK8 protein CTD PMID:31722249 indoxyl sulfate multiple interactions ISO RGD:732272 6480464 Indican results in increased expression of and results in increased phosphorylation of MAPK8 protein CTD PMID:30849338 indoxyl sulfate increases phosphorylation ISO RGD:621506 6480464 Indican results in increased phosphorylation of MAPK8 protein CTD PMID:32045570 iomeprol increases phosphorylation EXP 6480464 iomeprol results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 isoprenaline multiple interactions ISO RGD:732272 6480464 candesartan inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:20562518 isoprenaline increases activity ISO RGD:621506 6480464 Isoproterenol results in increased activity of MAPK8 protein CTD PMID:10591028 isoprenaline multiple interactions ISO RGD:621506 6480464 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK8 protein] CTD PMID:15951400 isoprenaline increases phosphorylation ISO RGD:621506 6480464 Isoproterenol results in increased phosphorylation of MAPK8 protein CTD PMID:15951400 isoprenaline increases phosphorylation ISO RGD:732272 6480464 Isoproterenol results in increased phosphorylation of MAPK8 protein CTD PMID:20562518 isorhamnetin multiple interactions ISO RGD:621506 6480464 3-methylquercetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:19222219 Isorhapontigenin multiple interactions ISO RGD:621506 6480464 isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 ivermectin multiple interactions ISO RGD:732272 6480464 Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein] CTD PMID:19168156 ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of MAPK8 protein CTD PMID:32959892 kaempferol increases phosphorylation EXP 6480464 kaempferol results in increased phosphorylation of MAPK8 protein CTD PMID:30499162 kanamycin A increases phosphorylation ISO RGD:621506 6480464 Kanamycin results in increased phosphorylation of MAPK8 protein CTD PMID:17570507 ketoconazole increases phosphorylation EXP 6480464 Ketoconazole results in increased phosphorylation of MAPK8 protein CTD PMID:19631732 ketoconazole increases expression ISO RGD:621506 6480464 Ketoconazole results in increased expression of MAPK8 mRNA CTD PMID:25787151 KN-93 multiple interactions ISO RGD:621506 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21933187 kojic acid decreases expression EXP 6480464 kojic acid results in decreased expression of MAPK8 mRNA CTD PMID:16595896 L-1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 L-ascorbic acid multiple interactions EXP 6480464 [Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:20206247 , PMID:24488945 L-cysteine multiple interactions ISO RGD:621506 6480464 [Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK8 protein, MAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency] CTD PMID:11312036 , PMID:11709198 L-methionine increases activity EXP 6480464 Methionine deficiency results in increased activity of MAPK8 protein CTD PMID:11880182 L-methionine multiple interactions ISO RGD:732272 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein, Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 L-methionine multiple interactions ISO RGD:621506 6480464 [Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK8 protein, MAPK8 mutant form results in decreased susceptibility to [sodium arsenite co-treated with Cysteine deficiency co-treated with Methionine deficiency] CTD PMID:11312036 , PMID:11709198 lactacystin increases activity ISO RGD:732272 6480464 lactacystin results in increased activity of MAPK8 protein CTD PMID:15618349 lactacystin increases phosphorylation ISO RGD:621506 6480464 lactacystin results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 lactacystin increases activity ISO RGD:621506 6480464 lactacystin results in increased activity of MAPK8 protein CTD PMID:15618349 lead diacetate multiple interactions ISO RGD:621506 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:20829427 , PMID:25088297 lead diacetate affects expression ISO RGD:621506 6480464 lead acetate affects the expression of MAPK8 CTD PMID:24293362 lead diacetate increases phosphorylation ISO RGD:621506 6480464 lead acetate results in increased phosphorylation of MAPK8 protein CTD PMID:25088297 lead(II) chloride increases expression EXP 6480464 lead chloride results in increased expression of MAPK8 protein modified form CTD PMID:24419708 Licochalcone A decreases phosphorylation EXP 6480464 licochalcone A results in decreased phosphorylation of MAPK8 protein CTD PMID:30187994 Licochalcone A multiple interactions EXP 6480464 licochalcone A promotes the reaction [Sorafenib results in decreased phosphorylation of MAPK8 protein], Sorafenib promotes the reaction [licochalcone A results in decreased phosphorylation of MAPK8 protein] CTD PMID:30187994 Licochalcone A increases expression EXP 6480464 licochalcone A results in increased expression of MAPK8 mRNA CTD PMID:30055311 Licochalcone B multiple interactions ISO RGD:732272 6480464 licochalcone B analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:25451593 lipoic acid multiple interactions ISO RGD:621506 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA CTD PMID:23830814 lipopolysaccharide increases phosphorylation EXP 150429951 lipopolysaccharide increases phosphorylation of MAPK8 protein in the pulmonary alveolus epithelium RGD lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:20307528 more ... lipopolysaccharide multiple interactions EXP 6480464 1 more ... CTD PMID:17698565 more ... lipopolysaccharide increases phosphorylation ISO RGD:621506 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:16934299 more ... lipopolysaccharide multiple interactions ISO RGD:621506 6480464 Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16934299 more ... lipopolysaccharide increases expression ISO RGD:732272 6480464 Lipopolysaccharides results in increased expression of MAPK8 protein modified form CTD PMID:15832817 lipopolysaccharide multiple interactions ISO RGD:732272 6480464 2'-hydroxyflavanone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11123339 more ... lipopolysaccharide increases phosphorylation ISO RGD:732272 6480464 Lipopolysaccharides results in increased phosphorylation of MAPK8 protein CTD PMID:11123339 more ... lipoteichoic acid multiple interactions ISO RGD:732272 6480464 [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein, TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein] CTD PMID:23238562 lithium atom increases expression ISO RGD:621506 6480464 Lithium results in increased expression of MAPK8 protein CTD PMID:18296634 lithium atom increases phosphorylation ISO RGD:621506 6480464 Lithium results in increased phosphorylation of MAPK8 protein CTD PMID:18296634 lithium hydride increases phosphorylation ISO RGD:621506 6480464 Lithium results in increased phosphorylation of MAPK8 protein CTD PMID:18296634 lithium hydride increases expression ISO RGD:621506 6480464 Lithium results in increased expression of MAPK8 protein CTD PMID:18296634 Longikaurin A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein] CTD PMID:28801140 Longikaurin A increases phosphorylation EXP 6480464 longikaurin A results in increased phosphorylation of MAPK8 protein CTD PMID:28801140 lovastatin multiple interactions ISO RGD:621506 6480464 Lovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form] CTD PMID:26739623 luteolin multiple interactions EXP 6480464 Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10718847 more ... luteolin increases phosphorylation EXP 6480464 Luteolin results in increased phosphorylation of MAPK8 protein CTD PMID:21601631 LY294002 multiple interactions ISO RGD:732272 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [flufenoxuron results in increased phosphorylation of MAPK8 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein] CTD PMID:11306679 , PMID:33771252 LY294002 multiple interactions ISO RGD:621506 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16018989 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:21420390 , PMID:26385185 lycopene decreases expression EXP 6480464 lycopene results in decreased expression of MAPK8 protein CTD PMID:17337101 Magnolol multiple interactions ISO RGD:732272 6480464 magnolol inhibits the reaction [trimethyltin results in increased phosphorylation of MAPK8 protein] CTD PMID:26756313 malonaldehyde multiple interactions ISO RGD:621506 6480464 MAPK8 protein promotes the reaction [Malondialdehyde results in increased expression of COL1A2 mRNA] CTD PMID:11295527 Malonoben multiple interactions EXP 6480464 tyrphostin A9 inhibits the reaction [S100A4 protein results in increased phosphorylation of MAPK8 protein] CTD PMID:16948116 manganese atom increases phosphorylation EXP 6480464 Manganese results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 manganese atom multiple interactions ISO RGD:621506 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 , PMID:32574669 manganese(0) increases phosphorylation EXP 6480464 Manganese results in increased phosphorylation of MAPK8 protein CTD PMID:17045426 manganese(0) multiple interactions ISO RGD:621506 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 , PMID:32574669 manganese(II) chloride increases activity EXP 6480464 manganese chloride results in increased activity of MAPK8 protein CTD PMID:20152896 manganese(II) chloride multiple interactions ISO RGD:621506 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of MAPK8 protein] CTD PMID:30951808 , PMID:32574669 manganese(II) chloride increases methylation EXP 6480464 manganese chloride results in increased methylation of MAPK8 gene CTD PMID:27913844 manganese(II) chloride increases phosphorylation ISO RGD:621506 6480464 manganese chloride results in increased phosphorylation of MAPK8 protein CTD PMID:24324973 manganese(II) chloride increases phosphorylation EXP 6480464 manganese chloride results in increased phosphorylation of MAPK8 protein CTD PMID:19084589 , PMID:20152896 mangiferin decreases expression ISO RGD:732272 6480464 mangiferin results in decreased expression of MAPK8 mRNA CTD PMID:15135318 manumycin A multiple interactions ISO RGD:732272 6480464 manumycin inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:19739265 marimastat multiple interactions ISO RGD:621506 6480464 marimastat inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein] CTD PMID:15574683 masoprocol multiple interactions EXP 6480464 Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of MAPK8 protein modified form] CTD PMID:17395008 mebendazole increases phosphorylation EXP 6480464 Mebendazole results in increased phosphorylation of MAPK8 protein CTD PMID:20848085 Mecamylamine multiple interactions ISO RGD:621506 6480464 Mecamylamine inhibits the reaction [Potassium deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:18222492 mechlorethamine increases phosphorylation ISO RGD:732272 6480464 Mechlorethamine results in increased phosphorylation of MAPK8 protein CTD PMID:25891025 melatonin increases expression EXP 6480464 Melatonin results in increased expression of MAPK8 protein CTD PMID:19012662 menadione multiple interactions ISO RGD:621506 6480464 Vitamin K 3 results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:19386027 menadione increases activity EXP 6480464 Vitamin K 3 results in increased activity of MAPK8 protein CTD PMID:12215205 menadione affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to Vitamin K 3 CTD PMID:12215205 menadione increases phosphorylation ISO RGD:621506 6480464 Vitamin K 3 results in increased phosphorylation of MAPK8 protein CTD PMID:16310883 mercaptoethanol multiple interactions EXP 6480464 Mercaptoethanol inhibits the reaction [Sodium Selenite results in decreased activity of MAPK8 protein] CTD PMID:10644709 mercury dichloride increases phosphorylation ISO RGD:732272 6480464 Mercuric Chloride results in increased phosphorylation of MAPK8 protein CTD PMID:10861847 more ... Mesna multiple interactions ISO RGD:732272 6480464 Mesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:19696094 metam multiple interactions ISO RGD:732272 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:15933225 methamphetamine increases phosphorylation ISO RGD:732272 6480464 Methamphetamine results in increased phosphorylation of MAPK8 protein CTD PMID:32768653 methotrexate increases phosphorylation ISO RGD:621506 6480464 Methotrexate results in increased phosphorylation of MAPK8 protein CTD PMID:20885979 methotrexate multiple interactions EXP 6480464 MAPK8 gene mutant form inhibits the reaction [Methotrexate results in increased expression of CDKN1A protein] CTD PMID:22183962 methoxychlor increases expression ISO RGD:732272 6480464 Methoxychlor results in increased expression of MAPK8 mRNA CTD PMID:20829426 methylglyoxal multiple interactions EXP 6480464 sulforaphane inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein] CTD PMID:25933243 methylglyoxal multiple interactions ISO RGD:732272 6480464 MAPK8 protein affects the reaction [Pyruvaldehyde results in increased expression of ACP5 mRNA] more ... CTD PMID:31103701 methylglyoxal increases phosphorylation ISO RGD:732272 6480464 Pyruvaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:31103701 methylglyoxal increases phosphorylation EXP 6480464 Pyruvaldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:25933243 methylmercury chloride increases phosphorylation ISO RGD:732272 6480464 methylmercuric chloride results in increased phosphorylation of MAPK8 protein CTD PMID:27667695 methylphenidate increases expression ISO RGD:732272 6480464 Methylphenidate results in increased expression of MAPK8 mRNA CTD PMID:22470460 methylseleninic acid increases expression EXP 6480464 methylselenic acid results in increased expression of MAPK8 mRNA CTD PMID:12517777 miconazole increases expression ISO RGD:621506 6480464 Miconazole results in increased expression of MAPK8 mRNA CTD PMID:22262564 microcystin-LR multiple interactions EXP 6480464 [IGBP1 protein results in increased susceptibility to cyanoginosin LR] which results in increased phosphorylation of MAPK8 protein CTD PMID:29984889 mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein results in increased phosphorylation of MAPK8 protein]] CTD PMID:10807665 minocycline decreases phosphorylation EXP 6480464 Minocycline results in decreased phosphorylation of MAPK8 protein CTD PMID:17872917 mitomycin C multiple interactions EXP 6480464 Mitomycin results in increased activity of and results in increased phosphorylation of MAPK8 protein CTD PMID:16186332 mono(2-ethylhexyl) phthalate affects phosphorylation EXP 6480464 mono-(2-ethylhexyl)phthalate affects the phosphorylation of MAPK8 protein CTD PMID:30810372 monodansylcadaverine multiple interactions ISO RGD:732272 6480464 monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:22341560 monosodium L-glutamate decreases expression ISO RGD:621506 6480464 Sodium Glutamate results in decreased expression of MAPK8 mRNA CTD PMID:28954212 morin multiple interactions ISO RGD:621506 6480464 morin inhibits the reaction [Ifosfamide results in increased activity of MAPK8 protein] CTD PMID:31722249 muscimol multiple interactions ISO RGD:732272 6480464 Muscimol inhibits the reaction [Ethanol results in increased expression of MAPK8 protein] CTD PMID:29044621 mycophenolic acid multiple interactions EXP 6480464 Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:20302854 mycophenolic acid decreases expression ISO RGD:621506 6480464 Mycophenolic Acid results in decreased expression of MAPK8 protein modified form CTD PMID:20302854 myricitrin multiple interactions EXP 6480464 myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 N(6),N(6)-dimethyladenine multiple interactions ISO RGD:621506 6480464 N(6), N(6)-dimethyladenine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15618353 N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide multiple interactions ISO RGD:621506 6480464 Tiapride Hydrochloride inhibits the reaction [4-iodo-2, 5-dimethoxyphenylisopropylamine results in increased phosphorylation of MAPK8 protein] CTD PMID:30790395 N-acetyl-L-cysteine multiple interactions ISO RGD:732272 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:10397638 more ... N-acetyl-L-cysteine multiple interactions EXP 150429751 N-acetyl-L-cysteine inhibits the reaction [Curcumin increases phosphorylation of MAPK8 protein in uterine cervix] RGD N-acetyl-L-cysteine decreases phosphorylation EXP 6480464 Acetylcysteine results in decreased phosphorylation of MAPK8 protein CTD PMID:24735948 N-acetyl-L-cysteine multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:17041759 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:12684028 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases phosphorylation ISO RGD:621506 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of MAPK8 protein CTD PMID:18463101 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases response to substance ISO RGD:732272 6480464 MAPK8 gene mutant form results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde CTD PMID:23593480 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:732272 6480464 MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA] CTD PMID:23593480 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions EXP 6480464 N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein, nordy inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:17377739 N-formyl-L-methionyl-L-leucyl-L-phenylalanine multiple interactions ISO RGD:621506 6480464 MAPK8 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Reactive Oxygen Species], N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17560994 N-methyl-4-phenylpyridinium increases activity ISO RGD:732272 6480464 1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein CTD PMID:11181820 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of MAPK8 mRNA CTD PMID:25234470 N-methyl-4-phenylpyridinium increases activity EXP 6480464 1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein CTD PMID:17240529 N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 RNF7 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of MAPK8 protein] CTD PMID:17240529 N-methyl-N'-nitro-N-nitrosoguanidine increases phosphorylation EXP 6480464 Methylnitronitrosoguanidine results in increased phosphorylation of MAPK8 protein CTD PMID:22001597 N-methyl-N-nitrosourea multiple interactions ISO RGD:732272 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein], MAPK8 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein] CTD PMID:18593901 N-methyl-N-nitrosourea increases phosphorylation ISO RGD:621506 6480464 Methylnitrosourea results in increased phosphorylation of MAPK8 protein CTD PMID:16168987 N-methyl-N-nitrosourea increases activity ISO RGD:621506 6480464 Methylnitrosourea results in increased activity of MAPK8 protein CTD PMID:18593901 N-methyl-N-nitrosourea multiple interactions ISO RGD:621506 6480464 Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein] more ... CTD PMID:12693035 more ... N-methyl-N-nitrosourea increases activity ISO RGD:732272 6480464 Methylnitrosourea results in increased activity of MAPK8 protein CTD PMID:18593901 N-methyl-N-nitrosourea decreases response to substance ISO RGD:732272 6480464 MAPK8 gene mutant form results in decreased susceptibility to Methylnitrosourea CTD PMID:18593901 N-Nitroso-N-methylurethane multiple interactions ISO RGD:621506 6480464 Nitrosomethylurethane results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:12693035 N-nitrosodiethylamine multiple interactions ISO RGD:732272 6480464 Butylated Hydroxyanisole inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein] more ... CTD PMID:15989949 more ... N-nitrosodiethylamine multiple interactions ISO RGD:621506 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA, [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK8 mRNA CTD PMID:23830814 N-nitrosodiethylamine increases response to substance ISO RGD:732272 6480464 MAPK8 protein results in increased susceptibility to Diethylnitrosamine, MAPK8 results in increased susceptibility to Diethylnitrosamine CTD PMID:16807293 , PMID:25496033 N-nitrosodiethylamine increases activity ISO RGD:732272 6480464 Diethylnitrosamine results in increased activity of MAPK8 protein CTD PMID:15989949 , PMID:18691550 N-nitrosodimethylamine multiple interactions ISO RGD:621506 6480464 Dimethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:12971962 Narciclasine multiple interactions ISO RGD:732272 6480464 narciclasine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:30738987 naringin multiple interactions ISO RGD:732272 6480464 naringin inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein] CTD PMID:22198281 neocuproine multiple interactions ISO RGD:621506 6480464 [[Copper binds to neocuproine] which results in increased activity of MAPK8 protein] which results in increased phosphorylation of JUN protein more ... CTD PMID:18056745 nickel dichloride multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [nickel chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21843586 nickel dichloride multiple interactions ISO RGD:732272 6480464 MAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 mRNA], MAPK8 affects the reaction [nickel chloride results in increased expression of PTGS2 protein] CTD PMID:17065197 nickel dichloride increases phosphorylation ISO RGD:621506 6480464 nickel chloride results in increased phosphorylation of MAPK8 protein CTD PMID:21843586 nickel sulfate multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein], SB 203580 promotes the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:18495191 nickel sulfate increases phosphorylation ISO RGD:732272 6480464 nickel sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:18467339 nickel sulfate multiple interactions ISO RGD:732272 6480464 MAP3K1 protein affects the reaction [nickel sulfate results in increased phosphorylation of MAPK8 protein] CTD PMID:18467339 nickel sulfate increases phosphorylation EXP 6480464 nickel sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:15588916 more ... niclosamide multiple interactions ISO RGD:732272 6480464 Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:28824321 nicotinamide multiple interactions ISO RGD:621506 6480464 Niacinamide inhibits the reaction [Methylnitrosourea results in increased phosphorylation of MAPK8 protein] CTD PMID:16168987 nicotine multiple interactions EXP 6480464 Curcumin inhibits the reaction [Nicotine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11592233 , PMID:20727180 nicotine increases activity ISO RGD:621506 6480464 Nicotine results in increased activity of MAPK8 protein CTD PMID:17021677 nicotine increases phosphorylation ISO RGD:732272 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:21511693 nicotine multiple interactions ISO RGD:621506 6480464 Nicotine promotes the reaction [MAPK8 protein results in increased phosphorylation of JUN protein] CTD PMID:17021677 nicotine increases expression ISO RGD:621506 6480464 Nicotine results in increased expression of MAPK8 mRNA CTD PMID:20426880 nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of MAPK8 protein CTD PMID:20727180 nitroprusside decreases expression ISO RGD:621506 6480464 Nitroprusside results in decreased expression of MAPK8 protein modified form CTD PMID:20132804 nitroprusside affects response to substance ISO RGD:621506 6480464 MAPK8 protein affects the susceptibility to Nitroprusside CTD PMID:20132804 nitroprusside multiple interactions ISO RGD:621506 6480464 MAPK8 protein affects the susceptibility to [Nitroprusside results in decreased expression of BCL2L1 mRNA] CTD PMID:20132804 nocodazole multiple interactions EXP 6480464 TP53 protein affects the reaction [Nocodazole results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 nocodazole increases phosphorylation EXP 6480464 Nocodazole results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 notoginsenoside R1 multiple interactions ISO RGD:621506 6480464 notoginsenoside R1 inhibits the reaction [APP protein modified form results in increased phosphorylation of MAPK8 protein] CTD PMID:24975829 ochratoxin A multiple interactions ISO RGD:621506 6480464 ochratoxin A results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17651772 ochratoxin A increases phosphorylation EXP 6480464 ochratoxin A results in increased phosphorylation of MAPK8 protein CTD PMID:31154016 okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of MAPK8 mRNA CTD PMID:28939011 oleanolic acid decreases phosphorylation EXP 6480464 Oleanolic Acid analog results in decreased phosphorylation of MAPK8 protein CTD PMID:26612655 olmesartan decreases activity ISO RGD:732272 6480464 olmesartan results in decreased activity of MAPK8 protein CTD PMID:17208988 olmesartan decreases expression ISO RGD:732272 6480464 olmesartan results in decreased expression of MAPK8 protein modified form CTD PMID:17208988 osthole increases phosphorylation EXP 6480464 osthol results in increased phosphorylation of MAPK8 protein CTD PMID:29319219 oxidopamine increases phosphorylation ISO RGD:621506 6480464 Oxidopamine results in increased phosphorylation of MAPK8 protein CTD PMID:25446857 oxidopamine multiple interactions EXP 6480464 puag-haad inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:18675900 , PMID:31176653 oxidopamine multiple interactions ISO RGD:732272 6480464 2-chloro-5-hydroxyphenylglycine affects the reaction [[GOPC protein affects the susceptibility to Oxidopamine] which affects the phosphorylation of MAPK8 protein] more ... CTD PMID:10397638 , PMID:33571554 oxidopamine multiple interactions ISO RGD:621506 6480464 salvin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:25446857 oxidopamine increases phosphorylation ISO RGD:732272 6480464 Oxidopamine results in increased phosphorylation of MAPK8 protein CTD PMID:33571554 oxidopamine increases phosphorylation EXP 6480464 Oxidopamine results in increased phosphorylation of MAPK8 protein CTD PMID:18675900 , PMID:31176653 ozone increases phosphorylation EXP 6480464 Ozone results in increased phosphorylation of MAPK8 protein CTD PMID:19536146 p-menthan-3-ol increases phosphorylation EXP 6480464 Menthol results in increased phosphorylation of MAPK8 protein CTD PMID:18955132 paclitaxel increases activity EXP 6480464 Paclitaxel results in increased activity of MAPK8 protein CTD PMID:11160861 paclitaxel increases phosphorylation EXP 6480464 Paclitaxel results in increased phosphorylation of MAPK8 protein CTD PMID:19426673 paclitaxel increases phosphorylation ISO RGD:732272 6480464 Paclitaxel results in increased phosphorylation of MAPK8 protein CTD PMID:11123339 paclitaxel multiple interactions EXP 6480464 [esculetin co-treated with Paclitaxel] results in increased expression of MAPK8 protein more ... CTD PMID:10075725 more ... paclitaxel multiple interactions ISO RGD:732272 6480464 CD14 protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein], ITGAM protein affects the reaction [Paclitaxel results in increased phosphorylation of MAPK8 protein] CTD PMID:11123339 paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of MAPK8 protein CTD PMID:16051289 paracetamol multiple interactions ISO RGD:732272 6480464 Acetaminophen results in increased activity of and affects the localization of MAPK8 protein more ... CTD PMID:17185352 more ... paracetamol increases phosphorylation ISO RGD:732272 6480464 Acetaminophen results in increased phosphorylation of MAPK8 protein CTD PMID:19931551 more ... paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of MAPK8 mRNA CTD PMID:27761495 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of MAPK8 mRNA CTD PMID:20732408 , PMID:27761495 paracetamol increases response to substance ISO RGD:621506 6480464 MAPK8 results in increased susceptibility to Acetaminophen CTD PMID:11562448 paracetamol multiple interactions ISO RGD:621506 6480464 Acetaminophen results in increased phosphorylation of and results in increased activity of MAPK8 protein, MAP2K4 mutant form inhibits the reaction [Acetaminophen results in increased activity of MAPK8 protein] CTD PMID:11562448 paracetamol increases response to substance ISO RGD:732272 6480464 MAPK8 protein results in increased susceptibility to Acetaminophen CTD PMID:18700144 paracetamol multiple interactions EXP 6480464 Acetaminophen results in increased phosphorylation of and affects the activity of MAPK8 protein CTD PMID:17185352 paraquat multiple interactions ISO RGD:621506 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Paraquat results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16687388 more ... paraquat increases phosphorylation EXP 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:28474156 paraquat increases phosphorylation ISO RGD:732272 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:28215578 paraquat increases phosphorylation ISO RGD:621506 6480464 Paraquat results in increased phosphorylation of MAPK8 protein CTD PMID:16687388 more ... paraquat multiple interactions EXP 6480464 MAPK8 protein affects the reaction [Paraquat results in increased expression of MUC5AC mRNA] more ... CTD PMID:17018646 more ... paroxetine increases activity ISO RGD:621506 6480464 Paroxetine results in increased activity of MAPK8 protein CTD PMID:17728140 paroxetine multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [Paroxetine results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:17728140 parthenolide multiple interactions EXP 6480464 parthenolide results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16921510 parthenolide multiple interactions ISO RGD:621506 6480464 parthenolide inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA] CTD PMID:30259999 parthenolide increases expression EXP 6480464 parthenolide results in increased expression of MAPK8 mRNA CTD PMID:16921510 PD 168393 multiple interactions EXP 6480464 PD168393 inhibits the reaction [2 more ... CTD PMID:16778083 pentanal decreases expression EXP 6480464 pentanal results in decreased expression of MAPK8 mRNA CTD PMID:26079696 Pentoxifylline increases expression EXP 6480464 Pentoxifylline results in increased expression of MAPK8 protein, Pentoxifylline results in increased expression of MAPK8 protein modified form CTD PMID:20804743 peptidoglycan increases phosphorylation EXP 6480464 Peptidoglycan results in increased phosphorylation of MAPK8 protein CTD PMID:21647617 perfluorooctane-1-sulfonic acid decreases phosphorylation ISO RGD:621506 6480464 perfluorooctane sulfonic acid results in decreased phosphorylation of MAPK8 protein CTD PMID:28973641 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid results in increased phosphorylation of and results in increased activity of MAPK8 protein] which affects the localization of BAX protein, perfluorooctane sulfonic acid results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:34006824 perifosine multiple interactions EXP 6480464 [perifosine co-treated with Butyrates] results in increased activity of MAPK8 protein more ... CTD PMID:15781658 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of MAPK8 mRNA CTD PMID:19159669 phenylephrine multiple interactions ISO RGD:621506 6480464 GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein] more ... CTD PMID:16385079 more ... phenylephrine increases phosphorylation ISO RGD:621506 6480464 Phenylephrine results in increased phosphorylation of MAPK8 protein CTD PMID:10727428 , PMID:16385079 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA more ... CTD PMID:14610070 more ... phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:732272 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein CTD PMID:20172950 more ... phorbol 13-acetate 12-myristate multiple interactions ISO RGD:732272 6480464 Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein], GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25496033 phorbol 13-acetate 12-myristate increases phosphorylation EXP 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein CTD PMID:16838270 more ... phorone multiple interactions ISO RGD:732272 6480464 [phorone co-treated with tert-Butylhydroperoxide] results in increased phosphorylation of MAPK8 protein CTD PMID:20423716 phosgene multiple interactions ISO RGD:621506 6480464 ethyl pyruvate inhibits the reaction [Phosgene results in increased phosphorylation of MAPK8 protein] CTD PMID:21818760 phosgene increases phosphorylation ISO RGD:621506 6480464 Phosgene results in increased phosphorylation of MAPK8 protein CTD PMID:21818760 phthalic anhydride increases phosphorylation EXP 6480464 phthalic anhydride results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 phthalic anhydride multiple interactions EXP 6480464 phthalic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 pipoxolan multiple interactions ISO RGD:732272 6480464 pipoxolan inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:32677756 pirinixic acid increases expression ISO RGD:621506 6480464 pirinixic acid results in increased expression of MAPK8 mRNA CTD PMID:12832660 pirinixic acid increases expression ISO RGD:732272 6480464 pirinixic acid results in increased expression of MAPK8 mRNA CTD PMID:17426115 , PMID:18301758 platycodin D increases activity EXP 6480464 platycodin D results in increased activity of MAPK8 protein CTD PMID:20412017 plitidepsin increases activity EXP 6480464 plitidepsin results in increased activity of MAPK8 protein CTD PMID:18089842 plitidepsin multiple interactions EXP 6480464 AKT1 protein affects the reaction [plitidepsin results in increased activity of MAPK8 protein] CTD PMID:18089842 potassium atom multiple interactions ISO RGD:621506 6480464 Mecamylamine inhibits the reaction [Potassium deficiency results in increased phosphorylation of MAPK8 protein] CTD PMID:18222492 potassium atom increases phosphorylation ISO RGD:621506 6480464 Potassium deficiency results in increased phosphorylation of MAPK8 protein CTD PMID:18222492 potassium chromate multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:10910949 potassium chromate increases phosphorylation EXP 6480464 potassium chromate(VI) results in increased phosphorylation of MAPK8 protein CTD PMID:10910949 pramipexole multiple interactions ISO RGD:621506 6480464 pramipexole inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:16362428 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:621506 6480464 Pregnenolone Carbonitrile results in increased expression of MAPK8 mRNA CTD PMID:19162173 proanthocyanidin multiple interactions ISO RGD:621506 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:25088297 procyanidin B3 multiple interactions ISO RGD:732272 6480464 [Lipopolysaccharides co-treated with procyanidin B3] results in decreased phosphorylation of MAPK8 protein more ... CTD PMID:22169119 prodigiosin decreases phosphorylation EXP 6480464 Prodigiosin results in decreased phosphorylation of MAPK8 protein CTD PMID:31077745 progesterone multiple interactions ISO RGD:621506 6480464 Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:16284289 prostaglandin E2 increases activity ISO RGD:732272 6480464 Dinoprostone results in increased activity of MAPK8 protein CTD PMID:16644903 prostaglandin E2 multiple interactions ISO RGD:732272 6480464 L-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK8 protein] CTD PMID:16644903 prostaglandin F2alpha increases phosphorylation ISO RGD:732272 6480464 Dinoprost results in increased phosphorylation of MAPK8 protein CTD PMID:24333336 prostaglandin F2alpha multiple interactions ISO RGD:732272 6480464 resveratrol inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein], SRT1720 inhibits the reaction [Dinoprost results in increased phosphorylation of MAPK8 protein] CTD PMID:24333336 protein kinase inhibitor multiple interactions EXP 6480464 Protein Kinase Inhibitors inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased phosphorylation of MAPK8 protein] CTD PMID:26385185 protein kinase inhibitor multiple interactions ISO RGD:621506 6480464 Protein Kinase Inhibitors inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21925238 pterostilbene multiple interactions EXP 6480464 pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein], pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:19447859 , PMID:24154491 puerarin multiple interactions EXP 6480464 arsenic trioxide promotes the reaction [puerarin results in increased expression of MAPK8 protein] CTD PMID:20416161 puerarin increases phosphorylation EXP 6480464 puerarin results in increased phosphorylation of MAPK8 protein CTD PMID:21884717 puerarin increases expression EXP 6480464 puerarin results in increased expression of MAPK8 protein CTD PMID:20416161 pyrrolidine dithiocarbamate multiple interactions ISO RGD:621506 6480464 [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10941151 more ... pyrrolidine dithiocarbamate increases activity ISO RGD:621506 6480464 pyrrolidine dithiocarbamic acid results in increased activity of MAPK8 protein CTD PMID:10658192 quercetin increases phosphorylation EXP 6480464 Quercetin results in increased phosphorylation of MAPK8 protein CTD PMID:18377872 more ... quercetin increases expression EXP 6480464 Quercetin results in increased expression of MAPK8 mRNA, Quercetin results in increased expression of MAPK8 protein modified form CTD PMID:19017364 , PMID:23727915 quercetin multiple interactions EXP 6480464 [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:10718847 more ... quinoline multiple interactions EXP 6480464 quinoline analog inhibits the reaction [MAP3K20 protein promotes the reaction [Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein]], quinoline analog results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:15737997 ramipril multiple interactions ISO RGD:621506 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein], Ramipril inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] CTD PMID:31062909 razoxane affects activity EXP 6480464 Razoxane affects the activity of MAPK8 CTD PMID:10487526 reactive oxygen species multiple interactions EXP 6480464 [[Bortezomib co-treated with Butyrates] results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:15173093 more ... reactive oxygen species multiple interactions ISO RGD:621506 6480464 MAPK8 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Reactive Oxygen Species] CTD PMID:17560994 resiniferatoxin increases activity EXP 6480464 resiniferatoxin results in increased activity of MAPK8 protein CTD PMID:9580328 resveratrol multiple interactions ISO RGD:732272 6480464 [resveratrol results in increased activity of MAPK8 protein] which results in increased phosphorylation of and results in increased activity of TRP53 protein more ... CTD PMID:11933078 more ... resveratrol decreases expression ISO RGD:621506 6480464 resveratrol results in decreased expression of MAPK8 protein modified form CTD PMID:27093858 resveratrol multiple interactions ISO RGD:621506 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:27093858 more ... resveratrol affects response to substance EXP 6480464 MAPK8 protein affects the susceptibility to resveratrol CTD PMID:20082299 resveratrol multiple interactions EXP 6480464 MAPK8 protein affects the reaction [resveratrol results in increased expression of PRF1 protein] more ... CTD PMID:15217905 more ... resveratrol increases phosphorylation EXP 6480464 resveratrol results in increased phosphorylation of MAPK8 protein CTD PMID:18347188 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of MAPK8 protein CTD PMID:18089832 resveratrol increases activity ISO RGD:732272 6480464 resveratrol results in increased activity of MAPK8 protein CTD PMID:11933078 , PMID:21679764 resveratrol decreases activity EXP 6480464 resveratrol results in decreased activity of MAPK8 protein CTD PMID:11408617 resveratrol decreases phosphorylation EXP 6480464 resveratrol results in decreased phosphorylation of MAPK8 protein CTD PMID:23437203 rifampicin multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]], Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 rimonabant multiple interactions ISO RGD:732272 6480464 Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1 more ... CTD PMID:18950629 Ro 31-8220 multiple interactions ISO RGD:621506 6480464 Ro 31-8220 inhibits the reaction [Arsenic results in decreased phosphorylation of and results in decreased activity of MAPK8 protein] CTD PMID:11756236 rosmarinic acid decreases phosphorylation ISO RGD:621506 6480464 rosmarinic acid results in decreased phosphorylation of MAPK8 protein CTD PMID:28789951 rotenone increases activity EXP 6480464 Rotenone results in increased activity of MAPK8 protein CTD PMID:10780954 rotenone increases expression EXP 6480464 Rotenone results in increased expression of MAPK8 mRNA CTD PMID:32368861 rotenone multiple interactions ISO RGD:621506 6480464 1-(1-acetyl-piperidine-4-yl)-3-adamantan-1-yl-urea inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:30472438 rotenone increases phosphorylation ISO RGD:621506 6480464 Rotenone results in increased phosphorylation of MAPK8 protein CTD PMID:30472438 rotenone multiple interactions ISO RGD:732272 6480464 Rotenone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:29906494 rotenone increases phosphorylation EXP 6480464 Rotenone results in increased phosphorylation of MAPK8 protein CTD PMID:31648047 , PMID:32368861 rotenone increases activity ISO RGD:732272 6480464 Rotenone results in increased activity of MAPK8 protein CTD PMID:11181820 rotenone multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]] more ... CTD PMID:10780954 more ... rottlerin multiple interactions EXP 6480464 rottlerin inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK8 protein], rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] CTD PMID:15917298 , PMID:20599481 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 [antimony trioxide co-treated with Buthionine Sulfoximine] results in decreased expression of MAPK8 protein more ... CTD PMID:14701702 , PMID:16112521 salubrinal multiple interactions ISO RGD:621506 6480464 [salubrinal results in increased expression of EIF2S1 protein modified form] which results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 salubrinal multiple interactions EXP 6480464 salubrinal inhibits the reaction [alpha-Tocopherol analog results in increased phosphorylation of MAPK8 protein], salubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:20686688 , PMID:21809093 Salvianolic acid A multiple interactions ISO RGD:732272 6480464 salvianolic acid A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:31654708 sanguinarine multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [sanguinarine results in increased phosphorylation of MAPK8 protein] CTD PMID:19135517 sanguinarine increases phosphorylation EXP 6480464 sanguinarine results in increased phosphorylation of MAPK8 protein CTD PMID:19135517 sappanchalcone increases phosphorylation EXP 6480464 sappanchalcone results in increased phosphorylation of MAPK8 protein CTD PMID:21963806 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [4-vinyl-2 more ... CTD PMID:13679210 more ... SB 203580 increases phosphorylation ISO RGD:621506 6480464 SB 203580 results in increased phosphorylation of MAPK8 protein CTD PMID:28087833 SB 203580 decreases activity EXP 6480464 SB 203580 results in decreased activity of MAPK8 protein CTD PMID:18089842 SB 203580 multiple interactions ISO RGD:621506 6480464 SB 203580 promotes the reaction [Acrolein results in increased phosphorylation of MAPK8 protein] CTD PMID:12487375 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SCH772984 multiple interactions ISO RGD:621506 6480464 SCH772984 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK8 protein] CTD PMID:28087833 SCH772984 decreases expression ISO RGD:621506 6480464 SCH772984 results in decreased expression of MAPK8 protein CTD PMID:28087833 selenium atom decreases phosphorylation ISO RGD:732272 6480464 Selenium results in decreased phosphorylation of MAPK8 protein CTD PMID:17997286 selenium atom multiple interactions EXP 6480464 Selenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:26187450 selenium atom decreases expression ISO RGD:732272 6480464 Selenium results in decreased expression of MAPK8 mRNA CTD PMID:28810182 selenomethionine multiple interactions EXP 6480464 Selenomethionine inhibits the reaction [Spermine results in increased activity of MAPK8 protein] CTD PMID:20121705 serpentine asbestos multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein] CTD PMID:24735948 serpentine asbestos increases phosphorylation EXP 6480464 Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein CTD PMID:15882436 , PMID:24735948 sertraline multiple interactions ISO RGD:621506 6480464 pyrazolanthrone inhibits the reaction [Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein], Sertraline results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:17728140 silibinin increases phosphorylation EXP 6480464 Silybin results in increased phosphorylation of MAPK8 protein CTD PMID:16777994 silibinin multiple interactions EXP 6480464 pifithrin inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein], pyrazolanthrone inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein] CTD PMID:16777994 silicon dioxide decreases expression ISO RGD:732272 6480464 Silicon Dioxide results in decreased expression of MAPK8 mRNA CTD PMID:19073995 silicon dioxide increases phosphorylation EXP 6480464 Silicon Dioxide analog results in increased phosphorylation of MAPK8 protein, Silicon Dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:24844442 more ... silicon dioxide increases phosphorylation ISO RGD:732272 6480464 Silicon Dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:27616297 silver atom affects expression EXP 6480464 Silver affects the expression of MAPK8 mRNA CTD PMID:22342292 silver atom increases phosphorylation ISO RGD:621506 6480464 Silver results in increased phosphorylation of MAPK8 protein CTD PMID:26702581 silver(0) affects expression EXP 6480464 Silver affects the expression of MAPK8 mRNA CTD PMID:22342292 silver(0) increases phosphorylation ISO RGD:621506 6480464 Silver results in increased phosphorylation of MAPK8 protein CTD PMID:26702581 simvastatin multiple interactions ISO RGD:732272 6480464 farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]], Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein] CTD PMID:18310456 simvastatin increases activity ISO RGD:732272 6480464 Simvastatin results in increased activity of MAPK8 protein CTD PMID:15187114 simvastatin multiple interactions ISO RGD:621506 6480464 Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:18047562 sirolimus multiple interactions EXP 6480464 [7-hydroxystaurosporine co-treated with Sirolimus] results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased phosphorylation of MAPK8 protein] CTD PMID:15767555 sodium arsenate increases phosphorylation EXP 6480464 sodium arsenate results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 sodium arsenite multiple interactions EXP 6480464 MAPK8 mutant form inhibits the reaction [sodium arsenite results in increased expression of ELK1 mRNA] more ... CTD PMID:21642427 more ... sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of MAPK8 mRNA CTD PMID:29301061 sodium arsenite decreases expression ISO RGD:732272 6480464 sodium arsenite results in decreased expression of MAPK8 mRNA CTD PMID:31233874 sodium arsenite increases phosphorylation ISO RGD:621506 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:11408547 more ... sodium arsenite increases expression ISO RGD:621506 6480464 sodium arsenite results in increased expression of MAPK8 mRNA, sodium arsenite results in increased expression of MAPK8 protein CTD PMID:24497207 , PMID:27966075 sodium arsenite increases activity ISO RGD:621506 6480464 sodium arsenite results in increased activity of MAPK8 protein CTD PMID:17658681 sodium arsenite decreases expression ISO RGD:621506 6480464 sodium arsenite results in decreased expression of MAPK8 protein CTD PMID:19072884 sodium arsenite multiple interactions ISO RGD:621506 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite co-treated with lead acetate] results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:11312036 more ... sodium arsenite increases phosphorylation ISO RGD:732272 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:16973625 more ... sodium arsenite increases expression ISO RGD:732272 6480464 sodium arsenite results in increased expression of MAPK8 mRNA more ... CTD PMID:19822182 more ... sodium arsenite multiple interactions ISO RGD:732272 6480464 [sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:16973625 more ... sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of MAPK8 protein CTD PMID:12482858 more ... sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of MAPK8 protein modified form CTD PMID:23219847 sodium arsenite increases activity EXP 6480464 sodium arsenite results in increased activity of MAPK8 protein CTD PMID:22706169 , PMID:23219847 sodium arsenite increases response to substance EXP 6480464 MAPK8 protein results in increased susceptibility to sodium arsenite CTD PMID:21726611 sodium dichromate affects expression ISO RGD:621506 6480464 sodium bichromate affects the expression of MAPK8 mRNA CTD PMID:11960910 sodium fluoride increases expression ISO RGD:621506 6480464 Sodium Fluoride results in increased expression of MAPK8 mRNA CTD PMID:30633982 sodium fluoride increases expression ISO RGD:732272 6480464 Sodium Fluoride results in increased expression of MAPK8 mRNA CTD PMID:32156525 sodium fluoride multiple interactions ISO RGD:732272 6480464 PTH protein promotes the reaction [Sodium Fluoride results in increased expression of MAPK8 mRNA] CTD PMID:32156525 sodium fluoride multiple interactions ISO RGD:621506 6480464 Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of MAPK8 mRNA] CTD PMID:30633982 Soman increases phosphorylation ISO RGD:621506 6480464 Soman results in increased phosphorylation of MAPK8 protein CTD PMID:21971501 Soman multiple interactions ISO RGD:621506 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 sorafenib multiple interactions EXP 6480464 [Bortezomib co-treated with Sorafenib] results in increased phosphorylation of MAPK8 protein more ... CTD PMID:16985072 , PMID:30187994 sorafenib decreases phosphorylation EXP 6480464 Sorafenib results in decreased phosphorylation of MAPK8 protein CTD PMID:30187994 spermine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Spermine results in increased activity of MAPK8 protein], Selenomethionine inhibits the reaction [Spermine results in increased activity of MAPK8 protein] CTD PMID:20121705 spermine increases activity EXP 6480464 Spermine results in increased activity of MAPK8 protein CTD PMID:20121705 SR 144528 multiple interactions ISO RGD:732272 6480464 SR 144528 inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK8 protein] CTD PMID:24184660 stavudine decreases phosphorylation EXP 6480464 Stavudine results in decreased phosphorylation of MAPK8 protein CTD PMID:27041070 streptozocin multiple interactions EXP 6480464 Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein] CTD PMID:25541468 streptozocin increases phosphorylation ISO RGD:621506 6480464 Streptozocin results in increased phosphorylation of MAPK8 protein CTD PMID:31062909 streptozocin multiple interactions ISO RGD:621506 6480464 [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:31062909 streptozocin increases phosphorylation ISO RGD:732272 6480464 Streptozocin results in increased phosphorylation of MAPK8 protein CTD PMID:30802477 streptozocin multiple interactions ISO RGD:732272 6480464 [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:26522834 more ... succimer multiple interactions ISO RGD:732272 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of MAPK8 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of MAPK8 mRNA CTD PMID:21641980 , PMID:26378955 sucrose multiple interactions EXP 6480464 Oligosaccharides inhibits the reaction [[Sucrose co-treated with Dietary Fats] affects the expression of MAPK8 mRNA] CTD PMID:31181236 sulforaphane increases activity EXP 6480464 sulforaphane results in increased activity of MAPK8 protein CTD PMID:16201852 sulforaphane multiple interactions EXP 6480464 sulforaphane inhibits the reaction [Pyruvaldehyde results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:25933243 , PMID:32387680 sulindac multiple interactions EXP 6480464 CDKN1A protein promotes the reaction [Sulindac results in increased expression of and results in increased phosphorylation of MAPK8 protein] more ... CTD PMID:15713900 more ... sulindac increases phosphorylation ISO RGD:732272 6480464 Sulindac results in increased phosphorylation of MAPK8 protein CTD PMID:17292881 sulindac increases expression ISO RGD:732272 6480464 Sulindac results in increased expression of MAPK8 mRNA CTD PMID:17292881 sulindac sulfide increases activity EXP 6480464 sulindac sulfide results in increased activity of MAPK8 protein CTD PMID:11051267 sulindac sulfone increases activity EXP 6480464 sulindac sulfone results in increased activity of MAPK8 protein CTD PMID:11051267 more ... sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of MAPK8 mRNA CTD PMID:31533062 superoxide increases phosphorylation ISO RGD:732272 6480464 Superoxides results in increased phosphorylation of MAPK8 protein CTD PMID:33290831 syringic acid decreases expression EXP 6480464 syringic acid results in decreased expression of MAPK8 mRNA CTD PMID:33759321 tacrolimus hydrate decreases activity ISO RGD:621506 6480464 Tacrolimus results in decreased activity of MAPK8 protein CTD PMID:12892836 tacrolimus hydrate multiple interactions ISO RGD:621506 6480464 Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of MAPK8 protein] CTD PMID:12892836 tamoxifen multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK8 protein] CTD PMID:14645110 tamoxifen multiple interactions ISO RGD:732272 6480464 Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased phosphorylation of MAPK8 protein], Tamoxifen inhibits the reaction [Dietary Fats results in increased phosphorylation of MAPK8 protein] CTD PMID:23038002 tamoxifen increases activity EXP 6480464 Tamoxifen results in increased activity of MAPK8 protein CTD PMID:14645110 Tanshinone I multiple interactions ISO RGD:732272 6480464 tanshinone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:29906494 taurine decreases expression ISO RGD:621506 6480464 Taurine results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 taurine multiple interactions ISO RGD:621506 6480464 [[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 , PMID:27501764 taurocholic acid multiple interactions ISO RGD:732272 6480464 NR1H4 gene mutant form promotes the reaction [Taurocholic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:28505368 TEMPO multiple interactions ISO RGD:732272 6480464 TEMPO inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] CTD PMID:33290831 tenofovir disoproxil fumarate affects phosphorylation EXP 6480464 Tenofovir affects the phosphorylation of MAPK8 protein CTD PMID:27041070 tert-butyl hydroperoxide multiple interactions ISO RGD:732272 6480464 [phorone co-treated with tert-Butylhydroperoxide] results in increased phosphorylation of MAPK8 protein CTD PMID:20423716 tert-butyl hydroperoxide multiple interactions EXP 6480464 LY96 protein promotes the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein] CTD PMID:28063877 tert-butyl hydroperoxide increases phosphorylation EXP 6480464 tert-Butylhydroperoxide results in increased phosphorylation of MAPK8 protein CTD PMID:28063877 tetracaine multiple interactions ISO RGD:621506 6480464 1 more ... CTD PMID:11981161 tetracaine increases phosphorylation ISO RGD:621506 6480464 Tetracaine results in increased phosphorylation of MAPK8 protein CTD PMID:11981161 tetrachloromethane increases phosphorylation ISO RGD:732272 6480464 Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein CTD PMID:20589743 more ... tetrachloromethane increases expression ISO RGD:621506 6480464 Carbon Tetrachloride results in increased expression of MAPK8 mRNA CTD PMID:31150632 tetrachloromethane increases phosphorylation ISO RGD:621506 6480464 Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein CTD PMID:17285312 , PMID:19066852 tetrachloromethane multiple interactions ISO RGD:732272 6480464 ferulic acid inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein], Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of MAPK8 protein] CTD PMID:20589743 , PMID:21291945 tetramethylpyrazine multiple interactions EXP 6480464 tetramethylpyrazine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein] CTD PMID:26404762 thapsigargin increases phosphorylation ISO RGD:621506 6480464 Thapsigargin results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 , PMID:32574669 thapsigargin multiple interactions ISO RGD:732272 6480464 imoxin inhibits the reaction [Thapsigargin results in increased phosphorylation of MAPK8 protein] CTD PMID:24150608 thapsigargin increases phosphorylation ISO RGD:732272 6480464 Thapsigargin results in increased phosphorylation of MAPK8 protein CTD PMID:24150608 thapsigargin multiple interactions ISO RGD:621506 6480464 GW 506033X inhibits the reaction [Thapsigargin results in increased phosphorylation of MAPK8 protein] CTD PMID:32574669 thimerosal increases phosphorylation EXP 6480464 Thimerosal results in increased phosphorylation of MAPK8 protein CTD PMID:18495191 thimerosal increases expression EXP 6480464 Thimerosal results in increased expression of MAPK8 mRNA CTD PMID:27188386 thioacetamide multiple interactions ISO RGD:621506 6480464 [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK8 mRNA, [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK8 mRNA CTD PMID:23830814 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of MAPK8 mRNA CTD PMID:22342292 titanium dioxide multiple interactions EXP 6480464 [Ferrosoferric Oxide binds to titanium dioxide] which results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 titanium dioxide increases phosphorylation EXP 6480464 titanium dioxide results in increased phosphorylation of MAPK8 protein CTD PMID:30098274 titanium dioxide increases expression ISO RGD:732272 6480464 titanium dioxide results in increased expression of MAPK8 mRNA CTD PMID:23557971 tofacitinib multiple interactions EXP 6480464 tofacitinib inhibits the reaction [OSM protein results in increased phosphorylation of MAPK8 protein] CTD PMID:21548952 toluene 2,4-diisocyanate increases phosphorylation EXP 6480464 Toluene 2, 4-Diisocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:33075463 toluene 2,4-diisocyanate multiple interactions ISO RGD:732272 6480464 pyrazolanthrone inhibits the reaction [Toluene 2, 4-Diisocyanate results in increased phosphorylation of MAPK8 protein] CTD PMID:33075463 toluene 2,4-diisocyanate increases phosphorylation ISO RGD:732272 6480464 Toluene 2, 4-Diisocyanate results in increased phosphorylation of MAPK8 protein CTD PMID:33075463 toluene 2,4-diisocyanate multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Toluene 2, 4-Diisocyanate results in increased phosphorylation of MAPK8 protein] CTD PMID:33075463 trans-anethole multiple interactions EXP 6480464 anethole inhibits the reaction [TNF protein results in increased activity of MAPK8 protein] CTD PMID:10871845 trans-chalcone multiple interactions ISO RGD:732272 6480464 Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:22155221 tributylstannane increases phosphorylation EXP 6480464 tributyltin results in increased phosphorylation of MAPK8 protein CTD PMID:21626652 tricetin multiple interactions EXP 6480464 tricetin inhibits the reaction [Oxidopamine results in increased phosphorylation of MAPK8 protein] CTD PMID:31176653 trichostatin A multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:15781658 more ... trichostatin A affects expression EXP 6480464 trichostatin A affects the expression of MAPK8 mRNA CTD PMID:28542535 trichostatin A decreases expression EXP 6480464 trichostatin A results in decreased expression of MAPK8 mRNA CTD PMID:22723015 , PMID:26272509 trifluoperazine multiple interactions EXP 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trifluoperazine multiple interactions ISO RGD:732272 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trifluoperazine multiple interactions ISO RGD:621506 6480464 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 trimellitic anhydride increases phosphorylation EXP 6480464 trimellitic anhydride results in increased phosphorylation of MAPK8 protein CTD PMID:27129696 trimellitic anhydride multiple interactions EXP 6480464 trimellitic anhydride inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:27129696 trimethylarsine oxide decreases expression ISO RGD:621506 6480464 trimethylarsine oxide results in decreased expression of MAPK8 mRNA CTD PMID:17481689 trimethyltin multiple interactions ISO RGD:732272 6480464 magnolol inhibits the reaction [trimethyltin results in increased phosphorylation of MAPK8 protein] CTD PMID:26756313 trimethyltin increases phosphorylation ISO RGD:732272 6480464 trimethyltin results in increased phosphorylation of MAPK8 protein CTD PMID:26756313 troglitazone decreases expression ISO RGD:732272 6480464 troglitazone results in decreased expression of MAPK8 mRNA CTD PMID:28973697 troglitazone multiple interactions EXP 6480464 troglitazone results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15064713 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO RGD:621506 6480464 [asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK8 protein] CTD PMID:21971501 trovafloxacin multiple interactions EXP 6480464 ATG5 protein affects the reaction [trovafloxacin results in increased phosphorylation of MAPK8 protein] CTD PMID:33609687 trovafloxacin increases phosphorylation EXP 6480464 trovafloxacin results in increased phosphorylation of MAPK8 protein CTD PMID:33609687 tunicamycin increases expression ISO RGD:732272 6480464 Tunicamycin results in increased expression of MAPK8 mRNA CTD PMID:17127020 tunicamycin increases phosphorylation ISO RGD:621506 6480464 Tunicamycin results in increased phosphorylation of MAPK8 protein CTD PMID:21147958 tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK8 protein], RTKI cpd inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein] CTD PMID:11329622 , PMID:26514923 tyrphostin AG 1478 multiple interactions ISO RGD:621506 6480464 RTKI cpd inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK8 protein] CTD PMID:15574683 U-73122 multiple interactions EXP 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:19927300 urethane increases expression EXP 6480464 Urethane results in increased expression of MAPK8 mRNA CTD PMID:28818685 ursolic acid multiple interactions ISO RGD:621506 6480464 2 more ... CTD PMID:27274199 valproic acid decreases expression ISO RGD:732272 6480464 Valproic Acid results in decreased expression of MAPK8 mRNA CTD PMID:21427059 valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of MAPK8 gene CTD PMID:29501571 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of MAPK8 mRNA CTD PMID:25716160 , PMID:29501571 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of MAPK8 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA CTD PMID:27188386 valproic acid increases phosphorylation ISO RGD:621506 6480464 Valproic Acid results in increased phosphorylation of MAPK8 protein CTD PMID:23378038 verapamil multiple interactions ISO RGD:621506 6480464 Verapamil inhibits the reaction [Gentamicins results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:15936777 Vernodalin multiple interactions EXP 6480464 MAPK8 protein affects the reaction [vernodalin results in increased phosphorylation of JUN protein] CTD PMID:32726518 vincaleukoblastine increases phosphorylation EXP 6480464 Vinblastine results in increased phosphorylation of MAPK8 protein CTD PMID:12221076 vincaleukoblastine multiple interactions EXP 6480464 TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein] CTD PMID:12221076 vinclozolin affects expression ISO RGD:732272 6480464 vinclozolin affects the expression of MAPK8 mRNA CTD PMID:34182078 vitamin E increases activity EXP 6480464 Vitamin E results in increased activity of MAPK8 protein CTD PMID:11522656 vitamin E decreases expression EXP 6480464 Vitamin E results in decreased expression of MAPK8 mRNA CTD PMID:19244175 vorinostat multiple interactions EXP 6480464 [3-(4-methylphenylsulfonyl)-2-propenenitrile co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein more ... CTD PMID:12893773 more ... WIN 55212-2 increases phosphorylation EXP 6480464 (3R)-((2 more ... CTD PMID:20619260 withaferin A increases phosphorylation EXP 6480464 withaferin A results in increased phosphorylation of MAPK8 protein CTD PMID:21964475 wogonin multiple interactions ISO RGD:732272 6480464 wogonin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:23362215 wortmannin multiple interactions ISO RGD:732272 6480464 wortmannin inhibits the reaction [3-(2-hydroxy-4-(1 more ... CTD PMID:18950629 wortmannin multiple interactions ISO RGD:621506 6480464 Wortmannin inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased phosphorylation of MAPK8 protein] CTD PMID:10611455 wortmannin decreases phosphorylation ISO RGD:732272 6480464 wortmannin results in decreased phosphorylation of MAPK8 protein CTD PMID:18950629 Yessotoxin increases activity ISO RGD:732272 6480464 yessotoxin results in increased activity of MAPK8 protein CTD PMID:21945047 zearalenone increases phosphorylation ISO RGD:732272 6480464 Zearalenone results in increased phosphorylation of MAPK8 protein CTD PMID:21767629 zearalenone increases expression ISO RGD:732272 6480464 Zearalenone results in increased expression of MAPK8 mRNA CTD PMID:30717214 zidovudine increases phosphorylation EXP 6480464 Zidovudine results in increased phosphorylation of MAPK8 protein CTD PMID:27041070 zinc acetate multiple interactions ISO RGD:621506 6480464 [Taurine co-treated with Zinc Acetate] results in decreased expression of MAPK8 protein modified form CTD PMID:27501764 zinc atom increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc atom multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 zinc atom multiple interactions ISO RGD:621506 6480464 [[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 , PMID:27501764 zinc atom multiple interactions EXP 6480464 [Clioquinol co-treated with Zinc] results in increased phosphorylation of MAPK8 protein CTD PMID:16648635 zinc dichloride multiple interactions ISO RGD:732272 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein] more ... CTD PMID:11306679 more ... zinc sulfate increases phosphorylation EXP 6480464 Zinc Sulfate results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc(0) increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of MAPK8 protein CTD PMID:16606632 zinc(0) multiple interactions ISO RGD:732272 6480464 [[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein, pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of MAPK8 protein] CTD PMID:30768131 zinc(0) multiple interactions ISO RGD:621506 6480464 [[Taurine binds to Zinc] which co-treated with poly(N-vinylpyrrolidine)] results in decreased expression of MAPK8 protein modified form more ... CTD PMID:26335259 , PMID:27501764 zinc(0) multiple interactions EXP 6480464 [Clioquinol co-treated with Zinc] results in increased phosphorylation of MAPK8 protein CTD PMID:16648635 zoledronic acid multiple interactions EXP 6480464 zoledronic acid promotes the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] CTD PMID:17059425
