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Gene: MAPK3 (mitogen-activated protein kinase 3) Homo sapiens
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Symbol: MAPK3
Name: mitogen-activated protein kinase 3
Description: Exhibits MAP kinase activity; identical protein binding activity; and phosphatase binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of macromolecule metabolic process; and protein phosphorylation. Localizes to the nuclear envelope. Implicated in colon adenocarcinoma; colorectal adenocarcinoma; endometrial adenocarcinoma; pancreatic ductal carcinoma; and pulmonary hypertension. Biomarker of endometrial adenocarcinoma; endometrial carcinoma; obesity; and schizophrenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ERK-1; ERK1; ERT2; extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; HS44KDAP; HUMKER1A; insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAPK 1; MAPK 3; MGC20180; microtubule-associated protein 2 kinase; mitogen-activated protein kinase 1; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3
Orthologs:
Mus musculus (house mouse) : Mapk3 (mitogen-activated protein kinase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mapk3 (mitogen activated protein kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk3 (mitogen-activated protein kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK3 (mitogen-activated protein kinase 3)
Canis lupus familiaris (dog) : MAPK3 (mitogen-activated protein kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk3 (mitogen-activated protein kinase 3)
Sus scrofa (pig) : MAPK3 (mitogen-activated protein kinase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,114,105 - 30,123,309 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371630,125,426 - 30,134,630 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,032,927 - 30,042,131 (-)NCBINCBI36hg18NCBI36
Build 341630,032,927 - 30,042,039NCBI
Celera1672,661,419 - 72,670,625 (+)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1627,786,557 - 27,795,763 (-)NCBIHuRef
CHM1_11631,341,181 - 31,350,385 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model