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Gene: TLR2 (toll like receptor 2) Homo sapiens
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Symbol: TLR2
Name: toll like receptor 2
Description: Exhibits several functions, including lipopolysaccharide binding activity; peptide binding activity; and peptidoglycan binding activity. Involved in several processes, including positive regulation of protein secretion; positive regulation of signal transduction; and response to bacterium. Localizes to several cellular components, including the Golgi apparatus; Toll-like receptor 1-Toll-like receptor 2 protein complex; and membrane raft. Implicated in several diseases, including Behcet's disease; autoimmune hypersensitivity disease (multiple); dermatitis (multiple); rhinitis (multiple); and tuberculosis (multiple). Biomarker of several diseases, including Behcet's disease; eye disease (multiple); lung disease (multiple); middle ear disease (multiple); and nose disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD282; TIL4; toll-like receptor 2; toll/interleukin 1 receptor-like 4; toll/interleukin-1 receptor-like protein 4
Orthologs:
Mus musculus (house mouse) : Tlr2 (toll-like receptor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tlr2 (toll-like receptor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr2 (toll like receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TLR2 (toll like receptor 2)
Canis lupus familiaris (dog) : TLR2 (toll like receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlr2 (toll like receptor 2)
Sus scrofa (pig) : TLR2 (toll like receptor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384153,684,080 - 153,710,643 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374154,605,404 - 154,627,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364154,824,891 - 154,846,693 (+)NCBINCBI36hg18NCBI36
Build 344154,966,670 - 154,984,135NCBI
Celera4151,929,928 - 151,951,730 (+)NCBI
Cytogenetic Map4q31.3NCBI
HuRef4150,336,457 - 150,358,268 (+)NCBIHuRef
CHM1_14154,583,774 - 154,605,783 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

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Sequence

Nucleotide Sequences
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