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Gene: PLAUR (plasminogen activator, urokinase receptor) Homo sapiens
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Symbol: PLAUR
Name: plasminogen activator, urokinase receptor
Description: Exhibits enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of homotypic cell-cell adhesion; and regulation of apoptotic signaling pathway. Localizes to the cell surface and plasma membrane. Implicated in rheumatoid arthritis. Biomarker of several diseases, including Lyme disease; cardiovascular system disease (multiple); end stage renal failure; hepatitis B; and melioidosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD87; monocyte activation antigen Mo3; U-PAR; u-plasminogen activator receptor form 2; UPAR; URKR; urokinase plasminogen activator surface receptor; urokinase-type plasminogen activator (uPA) receptor
Orthologs:
Mus musculus (house mouse) : Plaur (plasminogen activator, urokinase receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plaur (plasminogen activator, urokinase receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plaur (plasminogen activator, urokinase receptor)
Canis lupus familiaris (dog) : PLAUR (plasminogen activator, urokinase receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plaur (plasminogen activator, urokinase receptor)
Sus scrofa (pig) : PLAUR (plasminogen activator, urokinase receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1943,646,095 - 43,670,547 (-)Ensembl
GRCh381943,646,095 - 43,670,346 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371944,150,247 - 44,174,498 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361948,842,088 - 48,866,342 (-)NCBINCBI36hg18NCBI36
Build 341948,844,571 - 48,866,342NCBI
Celera1940,952,740 - 40,977,471 (-)NCBI
Cytogenetic Map19q13.31NCBI
HuRef1940,580,832 - 40,605,572 (-)NCBIHuRef
CHM1_11944,151,900 - 44,176,634 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PLAUR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735638
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-01-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.