MOXD2P (monooxygenase DBH like 2, pseudogene) - Rat Genome Database

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Gene: MOXD2P (monooxygenase DBH like 2, pseudogene) Homo sapiens
Analyze
Symbol: MOXD2P
Name: monooxygenase DBH like 2, pseudogene
RGD ID: 1641965
HGNC Page HGNC:33605
Description: Predicted to enable copper ion binding activity and dopamine beta-monooxygenase activity. Predicted to be involved in dopamine catabolic process; norepinephrine biosynthetic process; and octopamine biosynthetic process. Predicted to be active in extracellular space and secretory granule membrane.
Type: pseudo (Ensembl: transcribed_unprocessed_pseudogene)
RefSeq Status: VALIDATED
Previously known as: monooxygenase, DBH-like 2, pseudogene; MOXD2
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387142,240,737 - 142,247,067 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7142,240,740 - 142,247,067 (-)EnsemblGRCh38hg38GRCh38
GRCh377141,940,556 - 141,946,886 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367141,587,033 - 141,593,382 (+)NCBINCBI36Build 36hg18NCBI36
Celera7136,718,050 - 136,724,380 (-)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7136,235,297 - 136,241,627 (-)NCBIHuRef
CHM1_17141,874,709 - 141,881,039 (-)NCBICHM1_1
T2T-CHM13v2.07143,555,786 - 143,562,117 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27141,278,759 - 141,285,091 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
hypertension  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2144610   PMID:2426193   PMID:3011602   PMID:3860845   PMID:3983641   PMID:8650574   PMID:12853948   PMID:15489334   PMID:17642472   PMID:18523312   PMID:18777093   PMID:19051206  
PMID:19056690   PMID:19380806   PMID:21873635  


Genomics

Comparative Map Data
MOXD2P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387142,240,737 - 142,247,067 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7142,240,740 - 142,247,067 (-)EnsemblGRCh38hg38GRCh38
GRCh377141,940,556 - 141,946,886 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367141,587,033 - 141,593,382 (+)NCBINCBI36Build 36hg18NCBI36
Celera7136,718,050 - 136,724,380 (-)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7136,235,297 - 136,241,627 (-)NCBIHuRef
CHM1_17141,874,709 - 141,881,039 (-)NCBICHM1_1
T2T-CHM13v2.07143,555,786 - 143,562,117 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27141,278,759 - 141,285,091 (-)NCBI
Moxd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39640,855,728 - 40,864,428 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl640,855,728 - 40,864,428 (-)EnsemblGRCm39 Ensembl
GRCm38640,878,794 - 40,887,494 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl640,878,794 - 40,887,494 (-)EnsemblGRCm38mm10GRCm38
MGSCv37640,828,793 - 40,837,493 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36640,808,401 - 40,817,101 (-)NCBIMGSCv36mm8
Celera640,865,046 - 40,873,746 (-)NCBICelera
Cytogenetic Map6B1NCBI
cM Map618.92NCBI
Moxd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8470,691,373 - 70,699,868 (-)NCBIGRCr8
mRatBN7.2469,724,693 - 69,733,188 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl469,724,239 - 69,733,299 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx474,648,079 - 74,656,571 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0470,569,220 - 70,577,712 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0468,982,774 - 68,991,265 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0469,117,477 - 69,125,972 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl469,117,477 - 69,125,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04133,906,617 - 133,915,610 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4468,505,742 - 68,514,237 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera464,715,240 - 64,723,735 (-)NCBICelera
Cytogenetic Map4q23NCBI
MOXD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1167,019,646 - 7,042,005 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,878,452 - 7,900,885 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,940,707 - 6,963,133 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,941,194 - 6,963,034 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,894,193 - 6,904,823 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,735,320 - 6,745,957 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,804,208 - 6,826,638 (+)NCBIUU_Cfam_GSD_1.0
MOXD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1187,742,254 - 7,751,098 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2188,009,635 - 8,019,554 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:497
Count of miRNA genes:282
Interacting mature miRNAs:306
Transcripts:ENST00000460233, ENST00000477615
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium
Low 4 9 2 1 11 1 2 1 1 301 2 2
Below cutoff 385 538 161 125 620 29 449 143 522 25 161 128 97 101 337

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000460233
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7142,240,740 - 142,247,067 (-)Ensembl
RefSeq Acc Id: ENST00000477615
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7142,240,774 - 142,243,784 (-)Ensembl
RefSeq Acc Id: NR_024346
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387142,240,737 - 142,247,067 (-)NCBI
GRCh377141,940,556 - 141,946,886 (-)RGD
Celera7136,718,050 - 136,724,380 (-)RGD
HuRef7136,235,297 - 136,241,627 (-)RGD
CHM1_17141,874,709 - 141,881,039 (-)NCBI
T2T-CHM13v2.07143,555,786 - 143,562,117 (-)NCBI
CRA_TCAGchr7v27141,278,759 - 141,285,091 (-)ENTREZGENE
Sequence:
Protein Sequences
GenBank Protein A6NHM9 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
Protein Domains
DOMON

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6NHM9-F1-model_v2 AlphaFold A6NHM9 1-499 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:33605 AgrOrtholog
COSMIC MOXD2P COSMIC
Ensembl Genes ENSG00000240268 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000460233 ENTREZGENE
Gene3D-CATH 2.60.120.230 UniProtKB/Swiss-Prot
  2.60.120.310 UniProtKB/Swiss-Prot
GTEx ENSG00000240268 GTEx
HGNC ID HGNC:33605 ENTREZGENE
Human Proteome Map MOXD2P Human Proteome Map
InterPro Cu2_ascorb_mOase-like_C UniProtKB/Swiss-Prot
  Cu2_ascorb_mOase_N UniProtKB/Swiss-Prot
  Cu2_ascorb_mOase_N_sf UniProtKB/Swiss-Prot
  Cu2_monoox_C UniProtKB/Swiss-Prot
  DBH-like UniProtKB/Swiss-Prot
  DOH_DOMON UniProtKB/Swiss-Prot
  DOMON_domain UniProtKB/Swiss-Prot
  PHM/PNGase_F_dom_sf UniProtKB/Swiss-Prot
  Tbh/DBH UniProtKB/Swiss-Prot
NCBI Gene 100289017 ENTREZGENE
PANTHER PTHR10157 UniProtKB/Swiss-Prot
  PTHR10157:SF31 UniProtKB/Swiss-Prot
Pfam Cu2_monoox_C UniProtKB/Swiss-Prot
  Cu2_monooxygen UniProtKB/Swiss-Prot
  DOMON UniProtKB/Swiss-Prot
PRINTS DBMONOXGNASE UniProtKB/Swiss-Prot
PROSITE DOMON UniProtKB/Swiss-Prot
SMART DoH UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49742 UniProtKB/Swiss-Prot
UniProt A6NHM9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-26 MOXD2P  monooxygenase DBH like 2, pseudogene    monooxygenase, DBH-like 2, pseudogene  Symbol and/or name change 5135510 APPROVED
2011-07-27 MOXD2P  monooxygenase, DBH-like 2, pseudogene  MOXD2  monooxygenase, DBH-like 2 pseudogene  Symbol and/or name change 5135510 APPROVED