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Gene: AGTR2 (angiotensin II receptor type 2) Homo sapiens
Symbol: AGTR2
Name: angiotensin II receptor type 2
Description: Exhibits angiotensin type II receptor activity. Involved in several processes, including positive regulation of phosphoprotein phosphatase activity; regulation of signal transduction; and vasodilation. Predicted to localize to the plasma membrane. Implicated in IgA glomerulonephritis; end stage renal failure; hypoglycemia; intellectual disability; and vesicoureteral reflux. Biomarker of IgA glomerulonephritis; dilated cardiomyopathy; pancreatic cancer; renal cell carcinoma; and vesicoureteral reflux.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: angiotensin II receptor, type 2; angiotensin II type-2 receptor; AT2; ATGR2; MRX88; type-2 angiotensin II receptor
Mus musculus (house mouse) : Agtr2 (angiotensin II receptor, type 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Agtr2 (angiotensin II receptor, type 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Agtr2 (angiotensin II receptor type 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AGTR2 (angiotensin II receptor type 2)
Canis lupus familiaris (dog) : AGTR2 (angiotensin II receptor type 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Agtr2 (angiotensin II receptor type 2)
Sus scrofa (pig) : AGTR2 (angiotensin II receptor type 2)
Chlorocebus sabaeus (African green monkey) : AGTR2 (angiotensin II receptor type 2)
Heterocephalus glaber (naked mole-rat) : Agtr2 (angiotensin II receptor type 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX116,170,744 - 116,174,974 (+)Ensembl
GRCh38X116,170,744 - 116,174,974 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X115,301,958 - 115,306,225 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X115,215,986 - 115,220,253 (+)NCBINCBI36hg18NCBI36
Build 34X115,113,884 - 115,117,702NCBI
CeleraX115,832,555 - 115,836,822 (-)NCBI
Cytogenetic MapXq23NCBI
HuRefX104,838,955 - 104,843,260 (+)NCBIHuRef
CHM1_1X115,212,791 - 115,217,059 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Protein Structures
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on AGTR2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619558
Created: 2002-07-23
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.