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Gene: FBXO31 (F-box protein 31) Homo sapiens
Symbol: FBXO31
Name: F-box protein 31
Description: Exhibits cyclin binding activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; anaphase-promoting complex-dependent catabolic process; and mitotic G1 DNA damage checkpoint. Localizes to SCF ubiquitin ligase complex. Implicated in autosomal recessive non-syndromic intellectual disability.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp434B027; DKFZp434J1815; F-box only protein 31; FBX14; Fbx31; FBXO14; FLJ22477; MGC15419; MGC9527; MRT45; pp2386; putative breast cancer tumor-suppressor; SCF ubiquitin ligase specificity factor
Mus musculus (house mouse) : Fbxo31 (F-box protein 31)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxo31 (F-box protein 31)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo31 (F-box protein 31)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO31 (F-box protein 31)
Canis lupus familiaris (dog) : FBXO31 (F-box protein 31)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo31 (F-box protein 31)
Sus scrofa (pig) : FBXO31 (F-box protein 31)
Chlorocebus sabaeus (African green monkey) : FBXO31 (F-box protein 31)
Heterocephalus glaber (naked mole-rat) : Fbxo31 (F-box protein 31)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1687,326,987 - 87,392,142 (-)EnsemblGRCh38hg38GRCh38
GRCh381687,326,987 - 87,392,121 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371687,362,942 - 87,425,708 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361685,920,443 - 85,974,864 (-)NCBINCBI36hg18NCBI36
Build 341685,920,444 - 85,974,864NCBI
Celera1671,659,646 - 71,722,476 (-)NCBI
Cytogenetic Map16q24.2NCBI
HuRef1673,106,044 - 73,168,796 (-)NCBIHuRef
CHM1_11688,772,405 - 88,837,523 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FBXO31
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351564
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.