TP53 (tumor protein p53) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: TP53 (tumor protein p53) Homo sapiens
Analyze
Symbol: TP53
Name: tumor protein p53
RGD ID: 70502
HGNC Page HGNC
Description: Exhibits several functions, including enzyme binding activity; transcription factor binding activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including intracellular signal transduction; regulation of apoptotic process; and regulation of nucleobase-containing compound metabolic process. Localizes to several cellular components, including centrosome; chromatin; and nuclear lumen. Colocalizes with nuclear body and transcription factor TFIID complex. Implicated in several diseases, including Li-Fraumeni syndrome (multiple); carcinoma (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and open-angle glaucoma (multiple). Biomarker of several diseases, including carcinoma (multiple); hematologic cancer (multiple); oral mucosa leukoplakia; oral submucous fibrosis; and serous cystadenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antigen NY-CO-13; BCC7; BMFS5; cellular tumor antigen p53; FLJ92943; LFS1; mutant p53 protein; mutant tumor protein 53; P53; p53 antigen; p53 transformation suppressor; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; TRP53; truncated p53 protein; tumor protein 53; tumor suppressor p53; tumor suppressor TP53; tumor supressor p53
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl177,661,779 - 7,687,538 (-)EnsemblGRCh38hg38GRCh38
GRCh38177,668,421 - 7,687,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37177,571,739 - 7,590,808 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,512,445 - 7,531,642 (-)NCBINCBI36hg18NCBI36
Build 34177,512,463 - 7,531,642NCBI
Celera177,598,099 - 7,617,224 (-)NCBI
Cytogenetic Map17p13.1NCBI
HuRef177,465,169 - 7,484,283 (-)NCBIHuRef
CHM1_1177,580,866 - 7,600,003 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model