Gene: IL13RA1 (interleukin 13 receptor subunit alpha 1) Homo sapiens
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Symbol: IL13RA1
Name: interleukin 13 receptor subunit alpha 1
Description: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bB128O4.2.1 (interleukin 13 receptor, alpha 1); cancer/testis antigen 19; CD213A1; CD213a1 antigen; CT19; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13Ra; IL-13RA1; IL13 receptor alpha-1 chain; interleukin 13 receptor, alpha 1; interleukin-13 receptor subunit alpha-1; NR4
Orthologs:
Mus musculus (house mouse) : Il13ra1 (interleukin 13 receptor, alpha 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il13ra1 (interleukin 13 receptor subunit alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il13ra1 (interleukin 13 receptor subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IL13RA1 (interleukin 13 receptor subunit alpha 1)
Canis lupus familiaris (dog) : IL13RA1 (interleukin 13 receptor subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il13ra1 (interleukin 13 receptor subunit alpha 1)
Sus scrofa (pig) : IL13RA1 (interleukin 13 receptor subunit alpha 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X118,726,954 - 118,794,533 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X117,861,514 - 117,928,496 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X117,745,587 - 117,812,524 (+)NCBINCBI36hg18NCBI36
Build 34X117,643,440 - 117,710,378NCBI
CeleraX118,316,317 - 118,383,340 (+)NCBI
Cytogenetic MapXq24NCBI
HuRefX107,355,737 - 107,421,582 (+)NCBIHuRef
CHM1_1X117,772,468 - 117,839,397 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IL13RA1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347132
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-05-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.