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Gene: BDKRB2 (bradykinin receptor B2) Homo sapiens
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Symbol: BDKRB2
Name: bradykinin receptor B2
RGD ID: 737386
Description: Exhibits several functions, including bradykinin receptor activity; protein heterodimerization activity; and type 1 angiotensin receptor binding activity. Involved in arachidonic acid secretion. Localizes to endosome and plasma membrane. Implicated in asthma; chronic obstructive pulmonary disease; diabetic retinopathy; hypertension; and rhinitis. Biomarker of asthma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B2 bradykinin receptor; B2R; BK-2; BK-2 receptor; BK2; BKR2; BRB2; DKFZp686O088
Orthologs:
Mus musculus (house mouse) : Bdkrb2 (bradykinin receptor, beta 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bdkrb2 (bradykinin receptor B2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bdkrb2 (bradykinin receptor B2)
Pan paniscus (bonobo/pygmy chimpanzee) : BDKRB2 (bradykinin receptor B2)
Canis lupus familiaris (dog) : BDKRB2 (bradykinin receptor B2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bdkrb2 (bradykinin receptor B2)
Sus scrofa (pig) : BDKRB2 (bradykinin receptor B2)
Chlorocebus sabaeus (African green monkey) : BDKRB2 (bradykinin receptor B2)
Heterocephalus glaber (naked mole-rat) : Bdkrb2 (bradykinin receptor B2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1496,204,679 - 96,244,166 (+)EnsemblGRCh38hg38GRCh38
GRCh381496,204,839 - 96,244,164 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371496,671,016 - 96,710,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361495,740,950 - 95,780,542 (+)NCBINCBI36hg18NCBI36
Build 341495,740,949 - 95,780,536NCBI
Celera1476,726,862 - 76,766,386 (+)NCBI
Cytogenetic Map14q32.2NCBI
HuRef1476,856,277 - 76,895,774 (+)NCBIHuRef
CHM1_11496,610,085 - 96,649,595 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on BDKRB2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737386
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.