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GENE - TERM ANNOTATION REPORT

10 Annotations Found.

An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred from experiment (EXP)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:8952600 PMID:19047579 PMID:23603059 PMID:27292124


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Iwai J, etal., Eur J Pharmacol. 1993 Dec 1;248(4):341-4.
  • The annotation has been inferred from sequence orthology with Agtr1a (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 2 additional annotations were made from Iwai J, etal., Eur J Pharmacol. 1993 Dec 1;248(4):341-4.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1
  • Curation Notes: mRNA:increased expression:aortic endothelial cell


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred from electronic annotation (IEA)
    		•  
  • The annotation was made from Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
  • 619 additional annotations were made from Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Obata J, etal., J Hypertens. 2000 Sep;18(9):1247-55.
  • The annotation has been inferred from sequence orthology with Agtr1a (Rattus norvegicus)
  • 2 additional annotations were made from Obata J, etal., J Hypertens. 2000 Sep;18(9):1247-55.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Susic D, etal., J Hypertens. 2011 Apr;29(4):716-23.
  • The annotation has been inferred from sequence orthology with Agtr1a (Rattus norvegicus) [(IMP) inferred from mutant phenotype]
  • 5 additional annotations were made from Susic D, etal., J Hypertens. 2011 Apr;29(4):716-23.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Zhu S and Meng QH, Clin Chem Lab Med. 2006;44(3):282-4.
  • 5 additional annotations were made from Zhu S and Meng QH, Clin Chem Lab Med. 2006;44(3):282-4.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1
  • Qualifier: susceptibility
  • Curation Notes: DNA:polymorphism:3' utr:g.1166A>C


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from da Silva AQ, etal., Brain Res. 2011 Jan 12;1368:231-8. Epub 2010 Oct 30.
  • The annotation has been inferred from sequence orthology with Agtr1a (Rattus norvegicus) [(IMP) inferred from mutant phenotype]
  • 8 additional annotations were made from da Silva AQ, etal., Brain Res. 2011 Jan 12;1368:231-8. Epub 2010 Oct 30.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1
  • Curation Notes: associated with Sleep Apnea Syndromes


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred by association of genotype and phenotype (IAGP)
    		•  
  • The annotation was made from Xiang K, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1998 Feb 10;15(1):9-12.
  • 5 additional annotations were made from Xiang K, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 1998 Feb 10;15(1):9-12.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1
  • Qualifier: no_association
  • Curation Notes: DNA:polymorphism:3' utr:1166A>C


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Peng JF, etal., Hypertension. 1998 Jun;31(6):1317-23.
  • The annotation has been inferred from sequence orthology with Agtr1a (Rattus norvegicus) [(IMP) inferred from mutant phenotype]
  • 7 additional annotations were made from Peng JF, etal., Hypertension. 1998 Jun;31(6):1317-23.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1


    • An association has been curated linking AGTR1 and hypertension in Homo sapiens.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Hsu CN, etal., Int J Mol Sci. 2018 Aug 20;19(8):2459. doi: 10.3390/ijms19082459.
  • The annotation has been inferred from sequence orthology with Agtr1a (Rattus norvegicus) [(IEP) inferred from expression pattern]
  • 65 additional annotations were made from Hsu CN, etal., Int J Mol Sci. 2018 Aug 20;19(8):2459. doi: 10.3390/ijms19082459.
  • 1178 RGD objects have been annotated to hypertension  (DOID:10763)
  • 93 papers in RGD have been used to annotate AGTR1
  • Qualifier: treatment


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