GSK3B Human (+)-Tetrandrine decreases expression EXP 6480464 tetrandrine results in decreased expression of GSK3B protein modified form CTD PMID:25266202 GSK3B Human (-)-Arctigenin multiple interactions EXP 6480464 Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of GSK3B protein] CTD PMID:25380086 GSK3B Human (-)-Arctigenin decreases phosphorylation EXP 6480464 arctigenin results in decreased phosphorylation of GSK3B protein CTD PMID:25380086 GSK3B Human (-)-epigallocatechin 3-gallate increases phosphorylation EXP 6480464 epigallocatechin gallate results in increased phosphorylation of GSK3B protein CTD PMID:16968065 GSK3B Human (-)-epigallocatechin 3-gallate decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 epigallocatechin gallate results in decreased phosphorylation of GSK3B protein CTD PMID:34600025 GSK3B Human (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of GSK3B mRNA CTD PMID:22079256 GSK3B Human (-)-gambogic acid decreases activity EXP 6480464 gambogic acid results in decreased activity of GSK3B protein CTD PMID:19433130 GSK3B Human (25R)-cholest-5-ene-3beta,26-diol increases phosphorylation EXP 6480464 27-hydroxycholesterol results in increased phosphorylation of GSK3B protein CTD PMID:33131013 GSK3B Human (25R)-cholest-5-ene-3beta,26-diol multiple interactions EXP 6480464 27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein] more ... CTD PMID:33131013 GSK3B Human (R)-lipoic acid increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Thioctic Acid results in increased phosphorylation of GSK3B protein CTD PMID:19879292 GSK3B Human (R)-lipoic acid multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [amyloid beta-protein (25-35) results in decreased phosphorylation of GSK3B protein] and Thioctic Acid inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of GSK3B protein] CTD PMID:34133789 GSK3B Human (R)-lipoic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in increased expression of GSK3B mRNA] CTD PMID:27260466 GSK3B Human (R)-salsolinol decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 salsolinol results in decreased phosphorylation of GSK3B protein CTD PMID:23261589 GSK3B Human (S)-colchicine decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Colchicine results in decreased expression of GSK3B mRNA CTD PMID:18255150 GSK3B Human (S)-nicotine multiple interactions EXP 6480464 [Nicotine results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein CTD PMID:12511591 GSK3B Human (S)-nicotine multiple interactions ISO Gsk3b (Mus musculus) 6480464 Carbon Tetrachloride inhibits the reaction [Nicotine results in decreased expression of GSK3B mRNA] more ... CTD PMID:31945395 more ... GSK3B Human (S)-nicotine decreases expression ISO Gsk3b (Mus musculus) 6480464 Nicotine results in decreased expression of GSK3B mRNA and Nicotine results in decreased expression of GSK3B protein CTD PMID:33640489 and PMID:35411647 GSK3B Human (S)-nicotine increases expression ISO Gsk3b (Mus musculus) 6480464 Nicotine results in increased expression of GSK3B mRNA CTD PMID:31945395 and PMID:35411647 GSK3B Human 1,2-dimethylhydrazine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [chlorophyllin affects the reaction [1 and 2-Dimethylhydrazine results in increased mutagenesis of CTNNB1 gene]] inhibits the reaction [GSK3B protein results in increased phosphorylation of and results in increased ubiquitination of CTNNB1 protein] CTD PMID:12628520 GSK3B Human 1,2-dimethylhydrazine increases expression ISO Gsk3b (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of GSK3B mRNA CTD PMID:22206623 GSK3B Human 1,8-cineole multiple interactions ISO Gsk3b (Mus musculus) 6480464 Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein] and RHOA protein inhibits the reaction [Eucalyptol inhibits the reaction [Glucose results in increased expression of GSK3B protein]] CTD PMID:31483951 GSK3B Human 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea multiple interactions EXP 6480464 [N-(4-methoxybenzyl)-N'-(5-nitro-1 more ... CTD PMID:20540935 more ... GSK3B Human 1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea decreases activity ISO Gsk3b (Rattus norvegicus) 6480464 N-(4-methoxybenzyl)-N'-(5-nitro-1 and 3-thiazol-2-yl)urea results in decreased activity of GSK3B protein CTD PMID:16202587 GSK3B Human 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 chlorcyclizine results in decreased expression of GSK3B mRNA CTD PMID:21058326 GSK3B Human 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of GSK3B mRNA CTD PMID:17374397 GSK3B Human 1-chloro-2,4-dinitrobenzene increases expression ISO Gsk3b (Mus musculus) 6480464 Dinitrochlorobenzene results in increased expression of GSK3B mRNA CTD PMID:28219650 GSK3B Human 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Gsk3b (Mus musculus) 6480464 2 more ... CTD PMID:22891246 and PMID:23911879 GSK3B Human 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:22891246 and PMID:23911879 GSK3B Human 14-Deoxy-11,12-didehydroandrographolide multiple interactions ISO Gsk3b (Mus musculus) 6480464 14-deoxy-11 and 12-didehydroandrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein] CTD PMID:30248417 GSK3B Human 17alpha-ethynylestradiol increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of GSK3B mRNA CTD PMID:12655037 more ... GSK3B Human 17beta-estradiol increases phosphorylation EXP 6480464 Estradiol results in increased phosphorylation of GSK3B protein CTD PMID:16076840 GSK3B Human 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of GSK3B mRNA CTD PMID:22574217 GSK3B Human 17beta-estradiol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Estradiol inhibits the reaction [Progesterone results in decreased expression of GSK3B mRNA] CTD PMID:17170212 GSK3B Human 17beta-estradiol increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Estradiol results in increased phosphorylation of GSK3B protein CTD PMID:15845746 GSK3B Human 17beta-estradiol multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein] and Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein] CTD PMID:15845746 GSK3B Human 17beta-estradiol multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]] more ... CTD PMID:16076840 and PMID:26990689 GSK3B Human 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 1H-(1 more ... CTD PMID:19135050 GSK3B Human 2,2',4,4',5,5'-hexachlorobiphenyl decreases phosphorylation EXP 6480464 2 more ... CTD PMID:20394812 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA CTD PMID:11007951 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA CTD PMID:33387578 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein CTD PMID:27312872 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein CTD PMID:24231000 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein] CTD PMID:24231000 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased phosphorylation of GSK3B protein CTD PMID:23639626 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Gsk3b (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of GSK3B mRNA CTD PMID:15034205 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Gsk3b (Mus musculus) 6480464 AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSK3B mRNA] CTD PMID:15034205 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of GSK3B protein CTD PMID:18996433 GSK3B Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA] CTD PMID:11007951 GSK3B Human 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein CTD PMID:26165751 GSK3B Human 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] and Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] CTD PMID:26165751 GSK3B Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2 more ... CTD PMID:24218147 GSK3B Human 2,5-hexanedione decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 2 and 5-hexanedione results in decreased expression of GSK3B protein CTD PMID:31760062 GSK3B Human 2,6-dinitrotoluene affects expression ISO Gsk3b (Rattus norvegicus) 6480464 2 and 6-dinitrotoluene affects the expression of GSK3B mRNA CTD PMID:21346803 GSK3B Human 2-amino-2-deoxy-D-glucopyranose decreases phosphorylation EXP 6480464 Glucosamine results in decreased phosphorylation of GSK3B protein CTD PMID:33812996 GSK3B Human 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein] more ... CTD PMID:33812996 GSK3B Human 2-chloroethanol increases expression ISO Gsk3b (Mus musculus) 6480464 Ethylene Chlorohydrin results in increased expression of GSK3B mRNA CTD PMID:26962056 GSK3B Human 2-deoxy-D-glucose multiple interactions EXP 6480464 Deoxyglucose inhibits the reaction [arsenic trioxide results in increased phosphorylation of GSK3B protein] and Deoxyglucose inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 GSK3B Human 2-methylcholine affects expression EXP 6480464 beta-methylcholine affects the expression of GSK3B mRNA CTD PMID:21179406 GSK3B Human 2-nitrotoluene affects expression ISO Gsk3b (Rattus norvegicus) 6480464 2-nitrotoluene affects the expression of GSK3B mRNA CTD PMID:16460773 GSK3B Human 20-hydroxyecdysone multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ecdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein]] and Ecdysterone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein] CTD PMID:26048653 GSK3B Human 26-hydroxycholesterol increases phosphorylation EXP 6480464 27-hydroxycholesterol results in increased phosphorylation of GSK3B protein CTD PMID:33131013 GSK3B Human 26-hydroxycholesterol multiple interactions EXP 6480464 27-hydroxycholesterol inhibits the reaction [CTNNB1 protein binds to GSK3B protein] more ... CTD PMID:33131013 GSK3B Human 3',5'-cyclic AMP multiple interactions ISO Gsk3b (Mus musculus) 6480464 GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 GSK3B Human 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 mizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of GSK3B protein] CTD PMID:20502051 GSK3B Human 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Puromycin Aminonucleoside results in increased phosphorylation of GSK3B protein CTD PMID:20502051 GSK3B Human 3,3',4,4',5-pentachlorobiphenyl affects expression ISO Gsk3b (Mus musculus) 6480464 3 more ... CTD PMID:37080397 GSK3B Human 3,3',5,5'-tetrabromobisphenol A decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 tetrabromobisphenol A results in decreased expression of GSK3B mRNA CTD PMID:27914987 GSK3B Human 3,3',5-triiodo-L-thyronine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Triiodothyronine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of GSK3B protein] CTD PMID:36868496 GSK3B Human 3,3'-diindolylmethane decreases phosphorylation EXP 6480464 3 and 3'-diindolylmethane results in decreased phosphorylation of GSK3B protein CTD PMID:22290291 GSK3B Human 3,4-methylenedioxymethamphetamine increases expression ISO Gsk3b (Mus musculus) 6480464 N-Methyl-3 more ... CTD PMID:19285098 and PMID:20188158 GSK3B Human 3,4-methylenedioxymethamphetamine affects expression ISO Gsk3b (Rattus norvegicus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine affects the expression of GSK3B mRNA CTD PMID:30071829 GSK3B Human 3,5-diethoxycarbonyl-1,4-dihydrocollidine multiple interactions ISO Gsk3b (Mus musculus) 6480464 3 more ... CTD PMID:20512997 GSK3B Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Gsk3b (Mus musculus) 6480464 14-deoxy-11 more ... CTD PMID:27475717 more ... GSK3B Human 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [chlorophyllin affects the reaction [2-amino-3-methylimidazo(4 and 5-f)quinoline results in increased mutagenesis of CTNNB1 gene]] inhibits the reaction [GSK3B protein results in increased phosphorylation of and results in increased ubiquitination of CTNNB1 protein] CTD PMID:12628520 GSK3B Human 3-methyladenine multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] CTD PMID:30362509 GSK3B Human 3-methyladenine multiple interactions ISO Gsk3b (Mus musculus) 6480464 3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of GSK3B protein] CTD PMID:36402210 GSK3B Human 3-nitropropanoic acid multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 topiramate inhibits the reaction [3-nitropropionic acid results in decreased phosphorylation of GSK3B protein] CTD PMID:29753867 GSK3B Human 3-nitropropanoic acid decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 3-nitropropionic acid results in decreased phosphorylation of GSK3B protein CTD PMID:29753867 GSK3B Human 3-phenylprop-2-enal decreases expression ISO Gsk3b (Mus musculus) 6480464 cinnamaldehyde results in decreased expression of GSK3B mRNA CTD PMID:28219650 GSK3B Human 3alpha-hydroxy-5beta-pregnan-20-one decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Pregnanolone results in decreased expression of GSK3B protein CTD PMID:17443805 GSK3B Human 4,4'-sulfonyldiphenol decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 bisphenol S results in decreased expression of GSK3B mRNA CTD PMID:26186136 GSK3B Human 4,4'-sulfonyldiphenol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of GSK3B mRNA CTD PMID:36041667 GSK3B Human 4,4'-sulfonyldiphenol decreases methylation EXP 6480464 bisphenol S results in decreased methylation of GSK3B gene CTD PMID:31601247 GSK3B Human 4,4'-sulfonyldiphenol decreases expression ISO Gsk3b (Mus musculus) 6480464 bisphenol S results in decreased expression of GSK3B protein modified form CTD PMID:32750123 GSK3B Human 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions EXP 6480464 [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein CTD PMID:12511591 GSK3B Human 4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside multiple interactions ISO Gsk3b (Mus musculus) 6480464 lac dye inhibits the reaction [Dietary Fats results in decreased phosphorylation of GSK3B protein] CTD PMID:36828244 GSK3B Human 4-hydroxynon-2-enal decreases expression EXP 6480464 4-hydroxy-2-nonenal results in decreased expression of GSK3B mRNA CTD PMID:12419474 GSK3B Human 4-hydroxynon-2-enal decreases phosphorylation EXP 6480464 4-hydroxy-2-nonenal results in decreased phosphorylation of GSK3B protein CTD PMID:24825450 GSK3B Human 4-hydroxyphenyl retinamide decreases expression ISO Gsk3b (Mus musculus) 6480464 Fenretinide results in decreased expression of GSK3B mRNA CTD PMID:28973697 GSK3B Human 4-hydroxyphenyl retinamide multiple interactions EXP 6480464 6-Aminonicotinamide inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] more ... CTD PMID:25246272 GSK3B Human 4-hydroxyphenyl retinamide increases phosphorylation EXP 6480464 Fenretinide results in increased phosphorylation of GSK3B protein CTD PMID:25246272 GSK3B Human 4-nitrophenol decreases expression ISO Gsk3b (Mus musculus) 6480464 4-nitrophenol results in decreased expression of GSK3B mRNA CTD PMID:34673133 GSK3B Human 4-vinylcyclohexene dioxide affects expression ISO Gsk3b (Mus musculus) 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of GSK3B mRNA CTD PMID:20829426 GSK3B Human 5-(2-chloroethyl)-4-methylthiazole multiple interactions ISO Gsk3b (Mus musculus) 6480464 Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of GSK3B protein] CTD PMID:24892905 GSK3B Human 5-aza-2'-deoxycytidine decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Decitabine results in decreased expression of GSK3B protein CTD PMID:34536542 GSK3B Human 5-methoxypsoralen multiple interactions ISO Gsk3b (Mus musculus) 6480464 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] CTD PMID:34428446 GSK3B Human 5alpha-pregnane-3,20-dione decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 5-alpha-Dihydroprogesterone results in decreased expression of GSK3B protein CTD PMID:17443805 GSK3B Human 6-aminonicotinamide multiple interactions EXP 6480464 6-Aminonicotinamide inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 GSK3B Human 6-bromoindirubin-3'-oxime decreases activity EXP 6480464 6-bromoindirubin-3'-oxime results in decreased activity of GSK3B protein CTD PMID:17991738 GSK3B Human 6-bromoindirubin-3'-oxime increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 6-bromoindirubin-3'-oxime results in increased phosphorylation of GSK3B protein CTD PMID:17329570 GSK3B Human 6-bromoindirubin-3'-oxime multiple interactions ISO Gsk3b (Mus musculus) 6480464 [trametinib co-treated with 6-bromoindirubin-3'-oxime] affects the phosphorylation of GSK3B protein CTD PMID:37116855 GSK3B Human 6-bromoindirubin-3'-oxime increases phosphorylation EXP 6480464 6-bromoindirubin-3'-oxime results in increased phosphorylation of GSK3B protein CTD PMID:19727391 GSK3B Human 6-bromoindirubin-3'-oxime multiple interactions EXP 6480464 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]] more ... CTD PMID:19727391 and PMID:28414160 GSK3B Human 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:25536389 GSK3B Human [6]-Shogaol multiple interactions EXP 6480464 shogaol results in increased expression of and results in increased phosphorylation of GSK3B protein CTD PMID:27645308 GSK3B Human acetylsalicylic acid decreases phosphorylation EXP 6480464 Aspirin results in decreased phosphorylation of GSK3B protein CTD PMID:11593435 GSK3B Human acetylsalicylic acid increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Aspirin results in increased phosphorylation of GSK3B protein CTD PMID:12813129 GSK3B Human acetylsalicylic acid decreases activity EXP 6480464 Aspirin results in decreased activity of GSK3B protein CTD PMID:19966835 GSK3B Human acrylamide decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Acrylamide results in decreased phosphorylation of GSK3B protein CTD PMID:33421551 GSK3B Human acrylamide increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Acrylamide results in increased expression of GSK3B mRNA CTD PMID:38604440 GSK3B Human adenosine increases phosphorylation EXP 6480464 Adenosine results in increased phosphorylation of GSK3B protein CTD PMID:34070360 GSK3B Human adenosine increases expression EXP 6480464 Adenosine results in increased expression of GSK3B mRNA CTD PMID:34070360 GSK3B Human aflatoxin B1 multiple interactions EXP 6480464 [CYP2A13 protein co-treated with Aflatoxin B1] results in increased phosphorylation of GSK3B protein and MIR138-1 mRNA alternative form inhibits the reaction [[CYP2A13 protein co-treated with Aflatoxin B1] results in increased phosphorylation of GSK3B protein] CTD PMID:26084420 GSK3B Human aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of GSK3B gene CTD PMID:27153756 GSK3B Human AH23848 multiple interactions EXP 6480464 [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [GSK3B protein binds to AKT1 protein] more ... CTD PMID:19407222 GSK3B Human alachlor multiple interactions ISO Gsk3b (Mus musculus) 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 GSK3B Human aldehydo-D-glucosamine decreases phosphorylation EXP 6480464 Glucosamine results in decreased phosphorylation of GSK3B protein CTD PMID:33812996 GSK3B Human aldehydo-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein] more ... CTD PMID:33812996 GSK3B Human aldehydo-D-glucose multiple interactions EXP 6480464 [[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose more ... CTD PMID:21031461 more ... GSK3B Human aldehydo-D-glucose decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:33764184 GSK3B Human aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of GSK3B protein CTD PMID:35385194 GSK3B Human aldehydo-D-glucose increases expression ISO Gsk3b (Mus musculus) 6480464 Glucose results in increased expression of GSK3B protein CTD PMID:31483951 GSK3B Human aldehydo-D-glucose decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:26054749 and PMID:33764184 GSK3B Human aldehydo-D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of GSK3B protein CTD PMID:23690508 GSK3B Human aldehydo-D-glucose multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B mRNA more ... CTD PMID:18004065 more ... GSK3B Human aldehydo-D-glucose multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose more ... CTD PMID:22180358 more ... GSK3B Human aldehydo-D-glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:23954465 and PMID:35385194 GSK3B Human all-trans-retinoic acid decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Tretinoin results in decreased phosphorylation of GSK3B protein CTD PMID:16288212 GSK3B Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of GSK3B mRNA CTD PMID:33167477 GSK3B Human all-trans-retinoic acid multiple interactions EXP 6480464 [Tretinoin co-treated with BDNF protein] results in increased expression of GSK3B protein more ... CTD PMID:25614230 and PMID:37409350 GSK3B Human all-trans-retinoic acid increases phosphorylation EXP 6480464 Tretinoin results in increased phosphorylation of GSK3B protein CTD PMID:25614230 GSK3B Human all-trans-retinoic acid affects expression EXP 6480464 Tretinoin affects the expression of GSK3B mRNA CTD PMID:15498508 GSK3B Human all-trans-retinoic acid increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Tretinoin results in increased phosphorylation of GSK3B protein CTD PMID:16288212 GSK3B Human alpha-D-galactose multiple interactions ISO Gsk3b (Mus musculus) 6480464 Galactose results in increased expression of and results in decreased phosphorylation of GSK3B protein and gentiopicroside analog inhibits the reaction [Galactose results in increased expression of and results in decreased phosphorylation of GSK3B protein] CTD PMID:36878094 GSK3B Human alsterpaullone decreases activity EXP 6480464 alsterpaullone results in decreased activity of GSK3B protein CTD PMID:12534346 GSK3B Human aluminium hydroxide increases expression EXP 6480464 Aluminum Hydroxide results in increased expression of GSK3B protein CTD PMID:37409350 GSK3B Human aluminium hydroxide multiple interactions EXP 6480464 Aluminum Hydroxide promotes the reaction [[Tretinoin co-treated with BDNF protein] results in increased expression of GSK3B protein] more ... CTD PMID:37409350 GSK3B Human amino acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 Amino Acids inhibits the reaction [KL gene mutant form results in decreased phosphorylation of GSK3B protein] and H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in decreased phosphorylation of GSK3B protein]] CTD PMID:25309793 GSK3B Human amiodarone decreases phosphorylation EXP 6480464 Amiodarone results in decreased phosphorylation of GSK3B protein CTD PMID:26515726 GSK3B Human amiodarone decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Amiodarone results in decreased phosphorylation of GSK3B protein CTD PMID:26515726 GSK3B Human amitrole decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Amitrole results in decreased expression of GSK3B mRNA CTD PMID:38685447 GSK3B Human ammonium chloride affects expression ISO Gsk3b (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of GSK3B mRNA CTD PMID:16483693 GSK3B Human amphetamine increases response to substance ISO Gsk3b (Mus musculus) 6480464 GSK3B gene mutant form results in increased susceptibility to Amphetamine CTD PMID:20357757 GSK3B Human amphetamine decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Amphetamine results in decreased expression of GSK3B protein CTD PMID:16144542 GSK3B Human andrographolide multiple interactions ISO Gsk3b (Mus musculus) 6480464 andrographolide inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of GSK3B protein] CTD PMID:27475717 GSK3B Human andrographolide decreases phosphorylation EXP 6480464 andrographolide results in decreased phosphorylation of GSK3B protein CTD PMID:35917943 GSK3B Human antirheumatic drug increases expression EXP 6480464 Antirheumatic Agents results in increased expression of GSK3B mRNA CTD PMID:24449571 GSK3B Human Antrocin decreases phosphorylation EXP 6480464 antrocin results in decreased phosphorylation of GSK3B protein CTD PMID:21158420 GSK3B Human arachidonic acid multiple interactions EXP 6480464 [SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron] CTD PMID:19620254 GSK3B Human aristolochic acid A decreases expression EXP 6480464 aristolochic acid I results in decreased expression of GSK3B mRNA CTD PMID:33212167 GSK3B Human arsane increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Arsenic results in increased phosphorylation of GSK3B protein CTD PMID:22552367 GSK3B Human arsane multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 4 more ... CTD PMID:35993674 GSK3B Human arsane multiple interactions EXP 6480464 GSK3B affects the susceptibility to [Fluorides co-treated with Arsenic] CTD PMID:30890376 GSK3B Human arsane increases expression EXP 6480464 Arsenic results in increased expression of GSK3B protein CTD PMID:30890376 GSK3B Human arsane decreases expression EXP 6480464 Arsenic results in decreased expression of GSK3B mRNA CTD PMID:29107899 GSK3B Human arsane increases phosphorylation EXP 6480464 Arsenic results in increased phosphorylation of GSK3B protein CTD PMID:22552367 GSK3B Human arsenic atom increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Arsenic results in increased phosphorylation of GSK3B protein CTD PMID:22552367 GSK3B Human arsenic atom multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 4 more ... CTD PMID:35993674 GSK3B Human arsenic atom multiple interactions EXP 6480464 GSK3B affects the susceptibility to [Fluorides co-treated with Arsenic] CTD PMID:30890376 GSK3B Human arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of GSK3B protein CTD PMID:30890376 GSK3B Human arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of GSK3B mRNA CTD PMID:29107899 GSK3B Human arsenic atom increases phosphorylation EXP 6480464 Arsenic results in increased phosphorylation of GSK3B protein CTD PMID:22552367 GSK3B Human arsenite(3-) increases expression EXP 6480464 arsenite metabolite results in increased expression of GSK3B mRNA CTD PMID:18242949 GSK3B Human arsenite(3-) increases expression ISO Gsk3b (Mus musculus) 6480464 arsenite results in increased expression of GSK3B protein and arsenite results in increased expression of GSK3B protein modified form CTD PMID:24457827 GSK3B Human arsenous acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein] and Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] CTD PMID:30362509 and PMID:35226250 GSK3B Human arsenous acid affects response to substance EXP 6480464 GSK3B protein affects the susceptibility to Arsenic Trioxide CTD PMID:21278055 GSK3B Human arsenous acid decreases phosphorylation EXP 6480464 Arsenic Trioxide results in decreased phosphorylation of GSK3B protein CTD PMID:25416439 and PMID:32305283 GSK3B Human arsenous acid multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] more ... CTD PMID:21278055 more ... GSK3B Human arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GSK3B mRNA CTD PMID:22521957 GSK3B Human arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of GSK3B protein CTD PMID:21278055 more ... GSK3B Human arsenous acid increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Arsenic Trioxide results in increased phosphorylation of GSK3B protein CTD PMID:30362509 GSK3B Human aspartame increases phosphorylation EXP 6480464 Aspartame results in increased phosphorylation of GSK3B protein CTD PMID:33992720 GSK3B Human Atipamezole multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in decreased phosphorylation of GSK3B protein]] CTD PMID:30597158 GSK3B Human atrazine increases expression EXP 6480464 Atrazine results in increased expression of GSK3B mRNA CTD PMID:22378314 GSK3B Human avobenzone increases phosphorylation EXP 6480464 avobenzone results in increased phosphorylation of GSK3B protein CTD PMID:29981360 GSK3B Human Azoxymethane increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Azoxymethane results in increased phosphorylation of GSK3B protein CTD PMID:20681671 GSK3B Human Azoxymethane multiple interactions ISO Gsk3b (Mus musculus) 6480464 pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of GSK3B protein] CTD PMID:20681671 GSK3B Human baicalein decreases phosphorylation EXP 6480464 baicalein results in decreased phosphorylation of GSK3B protein CTD PMID:22820424 and PMID:36988316 GSK3B Human baicalein multiple interactions EXP 6480464 baicalein inhibits the reaction [Mitomycin results in increased phosphorylation of GSK3B protein] CTD PMID:34624459 GSK3B Human BAPTA multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 1 more ... CTD PMID:25433145 GSK3B Human Bardoxolone methyl increases phosphorylation EXP 6480464 bardoxolone methyl results in increased phosphorylation of GSK3B protein CTD PMID:25246272 GSK3B Human Bardoxolone methyl multiple interactions EXP 6480464 GSK3B protein mutant form inhibits the reaction [bardoxolone methyl results in increased expression of HMOX1 protein] and GSK3B protein mutant form inhibits the reaction [bardoxolone methyl results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 GSK3B Human belinostat increases phosphorylation EXP 6480464 belinostat results in increased phosphorylation of GSK3B protein CTD PMID:23671600 GSK3B Human bellidifolin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 bellidifolin inhibits the reaction [Hydrogen Peroxide results in increased expression of GSK3B mRNA] and bellidifolin inhibits the reaction [Hydrogen Peroxide results in increased expression of GSK3B protein] CTD PMID:36518482 GSK3B Human benzene multiple interactions ISO Gsk3b (Mus musculus) 6480464 Benzene affects the expression of and results in increased phosphorylation of GSK3B protein CTD PMID:30567741 GSK3B Human benzo[a]pyrene multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 GSK3B protein affects the reaction [Benzo(a)pyrene results in increased expression of HK2 mRNA] CTD PMID:22100782 GSK3B Human benzo[a]pyrene increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Benzo(a)pyrene results in increased expression of GSK3B protein CTD PMID:34283317 GSK3B Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of GSK3B intron CTD PMID:30157460 GSK3B Human benzo[a]pyrene decreases phosphorylation EXP 6480464 Benzo(a)pyrene results in decreased phosphorylation of GSK3B protein CTD PMID:30659931 GSK3B Human benzo[a]pyrene decreases methylation ISO Gsk3b (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of GSK3B exon and Benzo(a)pyrene results in decreased methylation of GSK3B intron CTD PMID:27901495 GSK3B Human benzo[a]pyrene decreases expression ISO Gsk3b (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of GSK3B mRNA CTD PMID:15034205 GSK3B Human benzo[a]pyrene multiple interactions ISO Gsk3b (Mus musculus) 6480464 AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of GSK3B mRNA] CTD PMID:15034205 GSK3B Human benzo[a]pyrene diol epoxide I affects expression EXP 6480464 7 more ... CTD PMID:20382639 GSK3B Human benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7 more ... CTD PMID:19150397 GSK3B Human berberine multiple interactions ISO Gsk3b (Mus musculus) 6480464 Berberine inhibits the reaction [Dexamethasone results in decreased expression of GSK3B mRNA] CTD PMID:20462044 GSK3B Human berberine increases phosphorylation EXP 6480464 Berberine results in increased phosphorylation of GSK3B protein CTD PMID:23954465 GSK3B Human berberine multiple interactions EXP 6480464 Berberine inhibits the reaction [Glucose results in decreased phosphorylation of GSK3B protein] CTD PMID:23954465 GSK3B Human beta-D-glucosamine decreases phosphorylation EXP 6480464 Glucosamine results in decreased phosphorylation of GSK3B protein CTD PMID:33812996 GSK3B Human beta-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein] more ... CTD PMID:33812996 GSK3B Human betulin multiple interactions EXP 6480464 [betulin co-treated with Oxygen deficiency] affects the phosphorylation of GSK3B protein CTD PMID:33181113 GSK3B Human betulinic acid increases phosphorylation EXP 6480464 Betulinic Acid results in increased phosphorylation of GSK3B protein CTD PMID:33181113 GSK3B Human betulinic acid multiple interactions EXP 6480464 [Betulinic Acid co-treated with Oxygen deficiency] results in increased phosphorylation of GSK3B protein CTD PMID:33181113 GSK3B Human bis(2-ethylhexyl) phthalate decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in decreased phosphorylation of GSK3B protein CTD PMID:22610992 and PMID:37364752 GSK3B Human bis(2-ethylhexyl) phthalate increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased phosphorylation of GSK3B protein CTD PMID:29669060 GSK3B Human bis(2-ethylhexyl) phthalate increases phosphorylation EXP 6480464 Diethylhexyl Phthalate results in increased phosphorylation of GSK3B protein CTD PMID:30944277 GSK3B Human bis(2-ethylhexyl) phthalate increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased phosphorylation of GSK3B protein CTD PMID:33484791 GSK3B Human bis(2-ethylhexyl) phthalate multiple interactions ISO Gsk3b (Mus musculus) 6480464 Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein] CTD PMID:33484791 GSK3B Human bis(2-ethylhexyl) phthalate multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Diethylhexyl Phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein] and MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of GSK3B protein] CTD PMID:28526321 and PMID:29669060 GSK3B Human bisphenol A multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of GSK3B mRNA more ... CTD PMID:25112833 more ... GSK3B Human bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of GSK3B protein CTD PMID:36232920 GSK3B Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GSK3B protein CTD PMID:34186270 GSK3B Human bisphenol A decreases expression ISO Gsk3b (Mus musculus) 6480464 bisphenol A results in decreased expression of GSK3B mRNA CTD PMID:35489422 GSK3B Human bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of GSK3B gene CTD PMID:31601247 GSK3B Human bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of GSK3B gene CTD PMID:31601247 GSK3B Human bisphenol A affects binding EXP 6480464 bisphenol A binds to GSK3B protein CTD PMID:34706627 GSK3B Human bisphenol A increases methylation ISO Gsk3b (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of GSK3B gene CTD PMID:28505145 GSK3B Human bisphenol A multiple interactions ISO Gsk3b (Mus musculus) 6480464 [bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in decreased expression of GSK3B mRNA more ... CTD PMID:28483554 more ... GSK3B Human bisphenol A decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 bisphenol A results in decreased phosphorylation of GSK3B protein CTD PMID:25112833 more ... GSK3B Human bisphenol A decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of GSK3B mRNA CTD PMID:26186136 GSK3B Human bisphenol A increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 bisphenol A results in increased phosphorylation of GSK3B protein CTD PMID:26923231 GSK3B Human bisphenol A decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 bisphenol A results in decreased phosphorylation of GSK3B protein CTD PMID:25637671 more ... GSK3B Human bisphenol A increases expression ISO Gsk3b (Rattus norvegicus) 6480464 bisphenol A results in increased expression of GSK3B mRNA CTD PMID:25181051 more ... GSK3B Human Bisphenol B increases expression EXP 6480464 bisphenol B results in increased expression of GSK3B protein CTD PMID:34186270 GSK3B Human bisphenol F decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 4 and 4'-bisphenol F results in decreased expression of GSK3B mRNA CTD PMID:26186136 GSK3B Human bisphenol F multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of GSK3B mRNA CTD PMID:36041667 GSK3B Human bisphenol F decreases expression ISO Gsk3b (Mus musculus) 6480464 bisphenol F results in decreased expression of GSK3B protein modified form CTD PMID:32750123 GSK3B Human bleomycin A2 multiple interactions EXP 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin and [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 GSK3B Human bleomycin A2 increases phosphorylation EXP 6480464 Bleomycin results in increased phosphorylation of GSK3B protein CTD PMID:19429264 GSK3B Human bortezomib multiple interactions EXP 6480464 [Bortezomib co-treated with lonafarnib] results in decreased expression of GSK3B protein modified form more ... CTD PMID:16118318 and PMID:24085292 GSK3B Human brazilein decreases expression EXP 6480464 brazilein results in decreased expression of GSK3B protein modified form CTD PMID:23948132 GSK3B Human bromochloroacetic acid affects expression ISO Gsk3b (Rattus norvegicus) 6480464 bromochloroacetic acid affects the expression of GSK3B mRNA CTD PMID:16460773 GSK3B Human Butylbenzyl phthalate increases phosphorylation EXP 6480464 butylbenzyl phthalate results in increased phosphorylation of GSK3B protein CTD PMID:22552774 GSK3B Human Butylbenzyl phthalate multiple interactions EXP 6480464 HDAC6 mutant form inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of GSK3B protein] CTD PMID:22552774 GSK3B Human Butylparaben decreases phosphorylation EXP 6480464 butylparaben results in decreased phosphorylation of GSK3B protein CTD PMID:29319206 GSK3B Human cadmium atom multiple interactions ISO Gsk3b (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein] CTD PMID:19126599 GSK3B Human cadmium atom increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Cadmium results in increased expression of GSK3B mRNA CTD PMID:39025289 GSK3B Human cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of GSK3B mRNA CTD PMID:36321828 GSK3B Human cadmium atom increases phosphorylation EXP 6480464 Cadmium results in increased phosphorylation of GSK3B protein CTD PMID:22884995 GSK3B Human cadmium atom multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of GSK3B protein more ... CTD PMID:27658547 and PMID:36868496 GSK3B Human cadmium atom affects response to substance ISO Gsk3b (Rattus norvegicus) 6480464 GSK3B protein affects the susceptibility to Cadmium CTD PMID:27658547 GSK3B Human cadmium atom multiple interactions EXP 6480464 [GSK3B mutant form results in decreased susceptibility to Cadmium] which results in decreased expression of ABCC1 mRNA more ... CTD PMID:22884995 and PMID:25273023 GSK3B Human cadmium atom decreases response to substance EXP 6480464 GSK3B mutant form results in decreased susceptibility to Cadmium CTD PMID:25273023 GSK3B Human cadmium atom increases response to substance ISO Gsk3b (Mus musculus) 6480464 GSK3B protein results in increased susceptibility to Cadmium CTD PMID:19126599 GSK3B Human cadmium atom increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Cadmium results in increased phosphorylation of GSK3B protein CTD PMID:19126599 GSK3B Human cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of GSK3B protein CTD PMID:24057571 and PMID:25118938 GSK3B Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of GSK3B mRNA CTD PMID:33129824 GSK3B Human cadmium dichloride decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased phosphorylation of GSK3B protein CTD PMID:31809235 GSK3B Human cadmium dichloride multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased phosphorylation of GSK3B protein more ... CTD PMID:31809235 and PMID:36868496 GSK3B Human cadmium dichloride multiple interactions EXP 6480464 Cadmium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:28527916 GSK3B Human cadmium dichloride increases expression ISO Gsk3b (Mus musculus) 6480464 Cadmium Chloride results in increased expression of GSK3B mRNA CTD PMID:26026611 and PMID:27377441 GSK3B Human cadmium dichloride multiple interactions ISO Gsk3b (Mus musculus) 6480464 [[Cadmium Chloride results in decreased activity of CHRM1 protein] which affects the expression of ACHE mRNA alternative form] which results in increased expression of GSK3B mRNA more ... CTD PMID:26026611 and PMID:27377441 GSK3B Human caffeine increases phosphorylation EXP 6480464 Caffeine results in increased phosphorylation of GSK3B protein CTD PMID:21229324 GSK3B Human caffeine decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Caffeine results in decreased phosphorylation of GSK3B protein CTD PMID:15126379 GSK3B Human caffeine multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Caffeine results in increased phosphorylation of GSK3B protein] CTD PMID:21229324 GSK3B Human calycosin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 7 more ... CTD PMID:36195188 GSK3B Human calyculin a multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 calyculin A promotes the reaction [Lithium Chloride results in increased phosphorylation of GSK3B protein] CTD PMID:12813129 GSK3B Human cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of GSK3B mRNA more ... CTD PMID:28025562 GSK3B Human cannabidiol multiple interactions EXP 6480464 [Cannabidiol co-treated with moringin] results in increased expression of GSK3B mRNA more ... CTD PMID:28025562 and PMID:30096889 GSK3B Human capsaicin multiple interactions EXP 6480464 Capsaicin promotes the reaction [CEBPB protein binds to ATF3 protein binds to GSK3B protein] and GSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA] CTD PMID:20110283 GSK3B Human capsazepine multiple interactions EXP 6480464 capsazepine inhibits the reaction [Cannabidiol results in decreased expression of GSK3B protein modified form] and capsazepine inhibits the reaction [Cannabidiol results in decreased expression of GSK3B protein] CTD PMID:28025562 GSK3B Human captan multiple interactions ISO Gsk3b (Mus musculus) 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 GSK3B Human carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of GSK3B mRNA CTD PMID:24752500 GSK3B Human carbon monoxide multiple interactions ISO Gsk3b (Mus musculus) 6480464 Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of GSK3B protein] CTD PMID:18037988 GSK3B Human carbon monoxide increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Carbon Monoxide results in increased phosphorylation of GSK3B protein CTD PMID:18845810 GSK3B Human carbon nanotube affects expression ISO Gsk3b (Mus musculus) 6480464 Nanotubes and Carbon affects the expression of GSK3B mRNA CTD PMID:23845593 GSK3B Human carbon nanotube decreases expression ISO Gsk3b (Mus musculus) 6480464 Nanotubes and Carbon analog results in decreased expression of GSK3B mRNA CTD PMID:25554681 GSK3B Human carboxy-PTIO multiple interactions EXP 6480464 1 more ... CTD PMID:35985571 GSK3B Human celastrol multiple interactions ISO Gsk3b (Mus musculus) 6480464 celastrol affects the reaction [APC protein mutant form affects the phosphorylation of GSK3B protein] CTD PMID:31715269 GSK3B Human celastrol decreases phosphorylation EXP 6480464 celastrol results in decreased phosphorylation of GSK3B protein CTD PMID:31715269 GSK3B Human celastrol multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [celastrol results in decreased phosphorylation of GSK3B protein] more ... CTD PMID:31715269 GSK3B Human celecoxib decreases phosphorylation EXP 6480464 Celecoxib results in decreased phosphorylation of GSK3B protein CTD PMID:17257745 GSK3B Human celecoxib multiple interactions EXP 6480464 GSK3B mutant form inhibits the reaction [Celecoxib results in increased expression of GDF15] CTD PMID:17257745 GSK3B Human chaetoglobosin A increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 chaetoglobosins results in increased phosphorylation of GSK3B protein CTD PMID:18040759 GSK3B Human chaetoglobosin A multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein] CTD PMID:18040759 GSK3B Human Chikusetsusaponin-V increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 ginsenoside Ro results in increased phosphorylation of GSK3B protein CTD PMID:32535096 GSK3B Human CHIR 99021 affects phosphorylation EXP 6480464 Chir 99021 affects the phosphorylation of GSK3B protein CTD PMID:27752740 GSK3B Human CHIR 99021 multiple interactions EXP 6480464 Chir 99021 inhibits the reaction [SC-66 compound results in decreased phosphorylation of GSK3B protein] CTD PMID:34687144 GSK3B Human CHIR 99021 multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Chir 99021 inhibits the reaction [Ketamine results in increased phosphorylation of GSK3B protein] CTD PMID:36334642 GSK3B Human CHIR 99021 decreases activity ISO Gsk3b (Rattus norvegicus) 6480464 Chir 99021 results in decreased activity of GSK3B protein CTD PMID:34283317 GSK3B Human CHIR 99021 multiple interactions ISO Gsk3b (Mus musculus) 6480464 Chir 99021 inhibits the reaction [1-Methyl-4-phenylpyridinium promotes the reaction [GSK3B protein binds to TFEB protein]] more ... CTD PMID:29883716 and PMID:30165626 GSK3B Human CHIR 99021 decreases activity ISO Gsk3b (Mus musculus) 6480464 Chir 99021 results in decreased activity of GSK3B protein CTD PMID:30165626 GSK3B Human chitosan multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of GSK3B protein] CTD PMID:28732690 GSK3B Human chloroethene increases expression ISO Gsk3b (Mus musculus) 6480464 Vinyl Chloride metabolite results in increased expression of GSK3B mRNA CTD PMID:26962056 GSK3B Human chloroethene multiple interactions ISO Gsk3b (Mus musculus) 6480464 Vinyl Chloride results in increased expression of and results in increased phosphorylation of GSK3B protein CTD PMID:36892438 GSK3B Human chlorogenic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 Chlorogenic Acid inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein] CTD PMID:36048341 GSK3B Human chlorophyllin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [chlorophyllin affects the reaction [1 more ... CTD PMID:12628520 GSK3B Human chlorpyrifos decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Chlorpyrifos results in decreased expression of GSK3B mRNA CTD PMID:18668222 GSK3B Human chlorpyrifos affects activity EXP 6480464 Chlorpyrifos affects the activity of GSK3B protein CTD PMID:34424684 GSK3B Human chlorpyrifos decreases expression ISO Gsk3b (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of GSK3B mRNA CTD PMID:37019170 GSK3B Human chlorpyrifos multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide affects the reaction [Chlorpyrifos affects the activity of GSK3B protein] more ... CTD PMID:33930485 and PMID:34424684 GSK3B Human chlorpyrifos increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Chlorpyrifos results in increased expression of GSK3B mRNA CTD PMID:30497708 GSK3B Human chlorpyrifos multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 kaempferol inhibits the reaction [Chlorpyrifos results in increased expression of GSK3B mRNA] CTD PMID:30497708 GSK3B Human chlorpyrifos increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Chlorpyrifos results in increased phosphorylation of GSK3B protein CTD PMID:29404631 GSK3B Human chlorpyrifos increases expression ISO Gsk3b (Mus musculus) 6480464 Chlorpyrifos results in increased expression of GSK3B mRNA CTD PMID:29665406 GSK3B Human chlorpyrifos multiple interactions ISO Gsk3b (Mus musculus) 6480464 [APOE protein results in increased susceptibility to Chlorpyrifos] which results in decreased phosphorylation of GSK3B protein and GSK3B protein affects the reaction [Chlorpyrifos results in increased phosphorylation of MAPT protein] CTD PMID:29404631 and PMID:29665406 GSK3B Human cholesterol multiple interactions EXP 6480464 CYP7A1 mRNA inhibits the reaction [Cholesterol results in increased phosphorylation of GSK3B protein] CTD PMID:28275691 GSK3B Human cholesterol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein more ... CTD PMID:31877369 GSK3B Human cholesterol increases phosphorylation EXP 6480464 Cholesterol results in increased phosphorylation of GSK3B protein CTD PMID:28275691 GSK3B Human choline multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GSK3B gene CTD PMID:20938992 GSK3B Human chromium atom multiple interactions ISO Gsk3b (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of GSK3B protein] CTD PMID:18569013 GSK3B Human chromium atom decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Chromium results in decreased phosphorylation of GSK3B protein CTD PMID:18569013 GSK3B Human chromium(6+) increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 chromium hexavalent ion results in increased phosphorylation of GSK3B protein CTD PMID:22552367 GSK3B Human chrysin 5,7-dimethyl ether multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 5 and 7-dimethoxyflavone promotes the reaction [Diethylnitrosamine results in increased phosphorylation of GSK3B protein] CTD PMID:21554863 GSK3B Human cilostazol affects phosphorylation ISO Gsk3b (Mus musculus) 6480464 cilostazol affects the phosphorylation of GSK3B protein CTD PMID:24254769 GSK3B Human cilostazol multiple interactions ISO Gsk3b (Mus musculus) 6480464 SIRT1 protein affects the reaction [cilostazol affects the phosphorylation of GSK3B protein] CTD PMID:24254769 GSK3B Human Cinobufagin multiple interactions EXP 6480464 GSK3B protein mutant form inhibits the reaction [cinobufagin results in decreased expression of RELA protein] more ... CTD PMID:23164673 GSK3B Human Cinobufagin affects response to substance EXP 6480464 GSK3B protein affects the susceptibility to cinobufagin CTD PMID:23164673 GSK3B Human Cinobufagin increases expression EXP 6480464 cinobufagin results in increased expression of GSK3B protein modified form CTD PMID:23164673 GSK3B Human cisplatin multiple interactions EXP 6480464 [NEAT1 protein affects the susceptibility to Cisplatin] which affects the expression of and affects the phosphorylation of GSK3B protein more ... CTD PMID:21821001 more ... GSK3B Human cisplatin increases expression ISO Gsk3b (Mus musculus) 6480464 Cisplatin results in increased expression of GSK3B protein CTD PMID:38014886 GSK3B Human cisplatin increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Cisplatin results in increased phosphorylation of GSK3B protein CTD PMID:31220555 GSK3B Human cisplatin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Lithium Chloride co-treated with Cisplatin] results in increased phosphorylation of GSK3B protein CTD PMID:31220555 GSK3B Human cisplatin multiple interactions ISO Gsk3b (Mus musculus) 6480464 cordycepin inhibits the reaction [Cisplatin results in increased expression of GSK3B protein] more ... CTD PMID:31220555 and PMID:38014886 GSK3B Human cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of GSK3B mRNA CTD PMID:27594783 GSK3B Human cisplatin decreases phosphorylation EXP 6480464 Cisplatin results in decreased phosphorylation of GSK3B protein CTD PMID:21603599 more ... GSK3B Human cisplatin decreases expression ISO Gsk3b (Mus musculus) 6480464 Cisplatin results in decreased expression of GSK3B mRNA CTD PMID:21151649 GSK3B Human clozapine increases phosphorylation EXP 6480464 Clozapine results in increased phosphorylation of GSK3B protein CTD PMID:19440698 GSK3B Human clozapine increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Clozapine results in increased expression of GSK3B protein CTD PMID:16144542 and PMID:19359144 GSK3B Human clozapine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3B protein] CTD PMID:16144542 GSK3B Human cobalt dichloride multiple interactions EXP 6480464 [lysophosphatidylethanolamine analog co-treated with cobaltous chloride] results in increased phosphorylation of GSK3B protein CTD PMID:25125499 GSK3B Human cocaine multiple interactions ISO Gsk3b (Mus musculus) 6480464 Cocaine results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:19328817 GSK3B Human cocaine increases activity ISO Gsk3b (Mus musculus) 6480464 Cocaine results in increased activity of GSK3B protein CTD PMID:19328817 GSK3B Human coenzyme Q10 multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 coenzyme Q10 inhibits the reaction [APP protein results in decreased phosphorylation of GSK3B protein] CTD PMID:22186599 GSK3B Human coenzyme Q10 multiple interactions ISO Gsk3b (Mus musculus) 6480464 coenzyme Q10 promotes the reaction [Acetaminophen results in increased phosphorylation of GSK3B protein] CTD PMID:34668565 GSK3B Human colforsin daropate hydrochloride multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Colforsin results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:15950778 GSK3B Human columbamine increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 columbamine results in increased phosphorylation of GSK3B protein CTD PMID:32535096 GSK3B Human conjugated linoleic acid increases activity EXP 6480464 Linoleic Acids and Conjugated results in increased activity of GSK3B protein CTD PMID:19800873 GSK3B Human conjugated linoleic acid decreases phosphorylation EXP 6480464 Linoleic Acids and Conjugated results in decreased phosphorylation of GSK3B protein CTD PMID:19800873 GSK3B Human copper atom multiple interactions EXP 6480464 [Copper binds to Thiosemicarbazones analog] which results in decreased activity of GSK3B protein more ... CTD PMID:19122148 more ... GSK3B Human copper atom multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of GSK3B protein more ... CTD PMID:34577062 GSK3B Human copper(0) multiple interactions EXP 6480464 [Copper binds to Thiosemicarbazones analog] which results in decreased activity of GSK3B protein more ... CTD PMID:19122148 more ... GSK3B Human copper(0) multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of GSK3B protein more ... CTD PMID:34577062 GSK3B Human copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of GSK3B mRNA CTD PMID:19549813 GSK3B Human copper(II) sulfate multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of GSK3B protein more ... CTD PMID:34577062 GSK3B Human cordycepin multiple interactions EXP 6480464 cordycepin inhibits the reaction [erastin results in increased expression of GSK3B protein] CTD PMID:38014886 GSK3B Human cordycepin increases expression EXP 6480464 cordycepin results in increased expression of GSK3B mRNA CTD PMID:34070360 GSK3B Human cordycepin increases phosphorylation EXP 6480464 cordycepin results in increased phosphorylation of GSK3B protein CTD PMID:34070360 GSK3B Human cordycepin multiple interactions ISO Gsk3b (Mus musculus) 6480464 cordycepin inhibits the reaction [Cisplatin results in increased expression of GSK3B protein] CTD PMID:38014886 GSK3B Human corynoline increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 corynoline results in increased phosphorylation of GSK3B protein CTD PMID:34477289 GSK3B Human coumarin increases phosphorylation EXP 6480464 coumarin results in increased phosphorylation of GSK3B protein CTD PMID:35688186 GSK3B Human crocidolite asbestos decreases phosphorylation EXP 6480464 Asbestos and Crocidolite results in decreased phosphorylation of GSK3B protein CTD PMID:17191120 GSK3B Human crocidolite asbestos decreases expression EXP 6480464 Asbestos and Crocidolite results in decreased expression of GSK3B mRNA CTD PMID:29523930 GSK3B Human Cryptotanshinone multiple interactions EXP 6480464 cryptotanshinone inhibits the reaction [Dinoprostone results in decreased expression of GSK3B protein] CTD PMID:30208247 GSK3B Human curcumin decreases phosphorylation EXP 6480464 Curcumin results in decreased phosphorylation of GSK3B protein CTD PMID:18790744 GSK3B Human curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [IL1B protein results in decreased expression of GSK3B mRNA] more ... CTD PMID:27645308 GSK3B Human curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of GSK3B mRNA CTD PMID:27645308 GSK3B Human curcumin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of GSK3B protein]] more ... CTD PMID:25541178 more ... GSK3B Human curcumin decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Curcumin results in decreased expression of GSK3B mRNA CTD PMID:25963729 GSK3B Human curcumin increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Curcumin results in increased phosphorylation of GSK3B protein CTD PMID:25963729 GSK3B Human curcumin decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Curcumin results in decreased phosphorylation of GSK3B protein CTD PMID:18006147 GSK3B Human curcumin increases expression EXP 6480464 Curcumin results in increased expression of GSK3B protein CTD PMID:19573523 GSK3B Human cyanidin cation multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 cyanidin inhibits the reaction [bisphenol A results in increased expression of GSK3B mRNA] CTD PMID:37843801 GSK3B Human cycloastragenol multiple interactions ISO Gsk3b (Rattus norvegicus) 267358468 cycloastragenol inhibits the reaction [acute myocardial infarction decreases expression of Gsk3b protein in myocardium] RGD GSK3B Human cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA] CTD PMID:11007951 GSK3B Human cyclosporin A multiple interactions EXP 6480464 [GSK3A protein co-treated with GSK3B protein] affects the reaction [Cyclosporine results in increased expression of SNAI1 protein] CTD PMID:22416070 GSK3B Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of GSK3B mRNA CTD PMID:22147139 and PMID:25562108 GSK3B Human cyclosporin A increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Cyclosporine results in increased phosphorylation of GSK3B protein CTD PMID:22416070 GSK3B Human cyclosporin A increases phosphorylation EXP 6480464 Cyclosporine results in increased phosphorylation of GSK3B protein CTD PMID:22416070 GSK3B Human D-glucose multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B mRNA more ... CTD PMID:18004065 more ... GSK3B Human D-glucose decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:33764184 GSK3B Human D-glucose increases expression EXP 6480464 Glucose results in increased expression of GSK3B protein CTD PMID:35385194 GSK3B Human D-glucose increases expression ISO Gsk3b (Mus musculus) 6480464 Glucose results in increased expression of GSK3B protein CTD PMID:31483951 GSK3B Human D-glucose decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:26054749 and PMID:33764184 GSK3B Human D-glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of GSK3B protein CTD PMID:23690508 GSK3B Human D-glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:23954465 and PMID:35385194 GSK3B Human D-glucose multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose more ... CTD PMID:22180358 more ... GSK3B Human D-glucose multiple interactions EXP 6480464 [[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose more ... CTD PMID:21031461 more ... GSK3B Human DDE affects activity EXP 6480464 Dichlorodiphenyl Dichloroethylene affects the activity of GSK3B protein CTD PMID:25386960 GSK3B Human DDE decreases expression EXP 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of GSK3B mRNA CTD PMID:38568856 GSK3B Human DDT increases phosphorylation EXP 6480464 DDT results in increased phosphorylation of GSK3B protein CTD PMID:24968063 GSK3B Human DDT multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of GSK3B protein] CTD PMID:24968063 GSK3B Human deguelin decreases phosphorylation EXP 6480464 deguelin results in decreased phosphorylation of GSK3B protein CTD PMID:19336726 and PMID:21472727 GSK3B Human deoxynivalenol increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 deoxynivalenol results in increased phosphorylation of GSK3B protein CTD PMID:15976193 GSK3B Human desferrioxamine B decreases phosphorylation EXP 6480464 Deferoxamine results in decreased phosphorylation of GSK3B protein CTD PMID:25246272 GSK3B Human desferrioxamine B multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Deferoxamine inhibits the reaction [[Copper Sulfate results in increased abundance of Copper] which results in decreased phosphorylation of GSK3B protein] CTD PMID:34577062 GSK3B Human desferrioxamine B multiple interactions EXP 6480464 Deferoxamine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 GSK3B Human desmopressin multiple interactions ISO Gsk3b (Mus musculus) 6480464 GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 GSK3B Human dexamethasone increases ubiquitination ISO Gsk3b (Rattus norvegicus) 6480464 Dexamethasone results in increased ubiquitination of GSK3B protein CTD PMID:24451375 GSK3B Human dexamethasone multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Dexamethasone results in increased expression of and results in decreased phosphorylation of GSK3B protein CTD PMID:20501703 GSK3B Human dexamethasone decreases expression ISO Gsk3b (Mus musculus) 6480464 Dexamethasone results in decreased expression of GSK3B mRNA CTD PMID:20462044 GSK3B Human dexamethasone multiple interactions ISO Gsk3b (Mus musculus) 6480464 14-deoxy-11 more ... CTD PMID:20462044 more ... GSK3B Human dexmedetomidine increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Dexmedetomidine results in increased phosphorylation of GSK3B protein CTD PMID:30597158 GSK3B Human dexmedetomidine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide more ... CTD PMID:30597158 and PMID:31187143 GSK3B Human Di-n-hexyl phthalate increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 di-n-hexyl phthalate results in increased phosphorylation of GSK3B protein CTD PMID:32693021 GSK3B Human diallyl disulfide increases phosphorylation EXP 6480464 diallyl disulfide results in increased phosphorylation of GSK3B protein CTD PMID:23663050 GSK3B Human diallyl trisulfide decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 diallyl trisulfide results in decreased expression of GSK3B protein CTD PMID:23453443 GSK3B Human diallyl trisulfide decreases expression EXP 6480464 diallyl trisulfide results in decreased expression of GSK3B protein modified form CTD PMID:29626521 GSK3B Human diallyl trisulfide increases phosphorylation EXP 6480464 diallyl trisulfide results in increased phosphorylation of GSK3B protein CTD PMID:23663050 GSK3B Human diarsenic trioxide affects response to substance EXP 6480464 GSK3B protein affects the susceptibility to Arsenic Trioxide CTD PMID:21278055 GSK3B Human diarsenic trioxide increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Arsenic Trioxide results in increased phosphorylation of GSK3B protein CTD PMID:30362509 GSK3B Human diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GSK3B mRNA CTD PMID:22521957 GSK3B Human diarsenic trioxide multiple interactions ISO Gsk3b (Mus musculus) 6480464 Arsenic Trioxide inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein] and Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] CTD PMID:30362509 and PMID:35226250 GSK3B Human diarsenic trioxide decreases phosphorylation EXP 6480464 Arsenic Trioxide results in decreased phosphorylation of GSK3B protein CTD PMID:25416439 and PMID:32305283 GSK3B Human diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of GSK3B protein CTD PMID:21278055 more ... GSK3B Human diarsenic trioxide multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] more ... CTD PMID:21278055 more ... GSK3B Human diazinon multiple interactions ISO Gsk3b (Mus musculus) 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 GSK3B Human diazinon affects expression ISO Gsk3b (Rattus norvegicus) 6480464 Diazinon affects the expression of GSK3B mRNA CTD PMID:22546817 GSK3B Human dibutyl phthalate decreases expression ISO Gsk3b (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of GSK3B mRNA CTD PMID:21266533 GSK3B Human dibutyl phthalate multiple interactions EXP 6480464 HDAC6 mutant form inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of GSK3B protein] CTD PMID:22552774 GSK3B Human dibutyl phthalate increases phosphorylation EXP 6480464 Dibutyl Phthalate results in increased phosphorylation of GSK3B protein CTD PMID:22552774 GSK3B Human diclofenac affects expression EXP 6480464 Diclofenac affects the expression of GSK3B mRNA CTD PMID:24752500 GSK3B Human Dictamnine multiple interactions EXP 6480464 dictamnine inhibits the reaction [FGF protein results in increased phosphorylation of GSK3B protein] and dictamnine inhibits the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein] CTD PMID:30266538 and PMID:34861243 GSK3B Human Dictamnine decreases phosphorylation EXP 6480464 dictamnine results in decreased phosphorylation of GSK3B protein CTD PMID:34861243 GSK3B Human Didymin multiple interactions EXP 6480464 didymin inhibits the reaction [INS protein results in decreased phosphorylation of GSK3B protein] CTD PMID:30928401 GSK3B Human dihydrolipoic acid multiple interactions EXP 6480464 dihydrolipoic acid inhibits the reaction [[Tretinoin co-treated with BDNF protein] results in increased expression of GSK3B protein] more ... CTD PMID:37409350 GSK3B Human dihydrolipoic acid increases expression EXP 6480464 dihydrolipoic acid results in increased expression of GSK3B protein CTD PMID:37409350 GSK3B Human dioxygen increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Oxygen deficiency results in increased phosphorylation of GSK3B protein CTD PMID:24658657 and PMID:36940862 GSK3B Human dioxygen increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of GSK3B mRNA CTD PMID:36940862 GSK3B Human dioxygen multiple interactions EXP 6480464 [betulin co-treated with Oxygen deficiency] affects the phosphorylation of GSK3B protein more ... CTD PMID:30266538 more ... GSK3B Human dioxygen decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Oxygen deficiency results in decreased phosphorylation of GSK3B protein CTD PMID:31610156 and PMID:33111559 GSK3B Human dioxygen multiple interactions ISO Gsk3b (Mus musculus) 6480464 PHLPP2 protein inhibits the reaction [Oxygen deficiency results in decreased phosphorylation of GSK3B protein] and SGMS2 protein promotes the reaction [Oxygen deficiency results in decreased phosphorylation of GSK3B protein] CTD PMID:31610156 and PMID:33111559 GSK3B Human dioxygen increases phosphorylation EXP 6480464 Oxygen deficiency results in increased phosphorylation of GSK3B protein CTD PMID:30266538 GSK3B Human dioxygen multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein] more ... CTD PMID:24058562 more ... GSK3B Human disodium cromoglycate multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Cromolyn Sodium co-treated with Chitosan] inhibits the reaction [Dimethylhydrazines results in increased expression of GSK3B protein] CTD PMID:28732690 GSK3B Human disodium selenite decreases expression EXP 6480464 Sodium Selenite results in decreased expression of GSK3B mRNA CTD PMID:18175754 GSK3B Human dizocilpine maleate increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Dizocilpine Maleate results in increased phosphorylation of GSK3B protein CTD PMID:15877933 GSK3B Human dizocilpine maleate increases expression EXP 6480464 Dizocilpine Maleate results in increased expression of GSK3B mRNA CTD PMID:31563592 GSK3B Human dizocilpine maleate multiple interactions EXP 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:31563592 GSK3B Human dobutamine affects response to substance ISO Gsk3b (Mus musculus) 6480464 GSK3B gene mutant form affects the susceptibility to Dobutamine CTD PMID:17901358 GSK3B Human donepezil hydrochloride multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Donepezil inhibits the reaction [amyloid beta-protein (1-42) results in increased phosphorylation of GSK3B protein] CTD PMID:36474082 GSK3B Human donepezil hydrochloride multiple interactions ISO Gsk3b (Mus musculus) 6480464 Donepezil inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein] CTD PMID:34874107 GSK3B Human dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:19620254 more ... GSK3B Human dorsomorphin multiple interactions ISO Gsk3b (Mus musculus) 6480464 dorsomorphin inhibits the reaction [[Resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose] CTD PMID:22180358 GSK3B Human doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of GSK3B protein CTD PMID:17339365 GSK3B Human doxorubicin multiple interactions ISO Gsk3b (Mus musculus) 6480464 Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased phosphorylation of GSK3B protein] CTD PMID:18037988 GSK3B Human doxorubicin decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Doxorubicin results in decreased phosphorylation of GSK3B protein CTD PMID:18037988 GSK3B Human doxorubicin multiple interactions EXP 6480464 methylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein] and Selenium inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein] CTD PMID:17339365 GSK3B Human elemental selenium multiple interactions EXP 6480464 [Selenium co-treated with Vitamin E] results in increased expression of GSK3B mRNA and Selenium inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein] CTD PMID:17339365 and PMID:19244175 GSK3B Human elemental selenium decreases phosphorylation EXP 6480464 Selenium results in decreased phosphorylation of GSK3B protein CTD PMID:17339365 GSK3B Human elemental selenium decreases expression EXP 6480464 Selenium results in decreased expression of GSK3B mRNA CTD PMID:19244175 GSK3B Human enalapril multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Enalapril inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein] CTD PMID:18806606 GSK3B Human endosulfan increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Endosulfan results in increased expression of GSK3B mRNA CTD PMID:29391264 GSK3B Human endosulfan multiple interactions ISO Gsk3b (Mus musculus) 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 GSK3B Human entinostat multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GSK3B mRNA CTD PMID:27188386 GSK3B Human entinostat decreases expression EXP 6480464 entinostat results in decreased expression of GSK3B mRNA CTD PMID:26272509 GSK3B Human enzacamene increases phosphorylation EXP 6480464 enzacamene results in increased phosphorylation of GSK3B protein CTD PMID:30597193 GSK3B Human erastin increases expression EXP 6480464 erastin results in increased expression of GSK3B protein CTD PMID:38014886 GSK3B Human erastin multiple interactions EXP 6480464 cordycepin inhibits the reaction [erastin results in increased expression of GSK3B protein] CTD PMID:38014886 GSK3B Human erlotinib hydrochloride decreases expression EXP 6480464 Erlotinib Hydrochloride results in decreased expression of GSK3B protein modified form CTD PMID:30136359 GSK3B Human estragole increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 estragole results in increased phosphorylation of GSK3B protein CTD PMID:29054680 GSK3B Human ethanol decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Ethanol results in decreased phosphorylation of GSK3B protein CTD PMID:19429258 more ... GSK3B Human ethanol affects splicing ISO Gsk3b (Mus musculus) 6480464 Ethanol affects the splicing of GSK3B mRNA CTD PMID:30319688 GSK3B Human ethanol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Ethanol results in decreased susceptibility to INS1 protein] which results in increased activity of GSK3B protein and Ethanol results in increased activity of and results in decreased phosphorylation of GSK3B protein CTD PMID:12700235 GSK3B Human ethanol increases phosphorylation EXP 6480464 Ethanol results in increased phosphorylation of GSK3B protein CTD PMID:26220687 GSK3B Human ethanol increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Ethanol results in increased phosphorylation of GSK3B protein CTD PMID:22459179 and PMID:28962519 GSK3B Human ethanol multiple interactions EXP 6480464 [Ethanol co-treated with sodium arsenite] results in increased phosphorylation of GSK3B protein more ... CTD PMID:19429258 more ... GSK3B Human ethanol multiple interactions ISO Gsk3b (Mus musculus) 6480464 Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of GSK3B protein] more ... CTD PMID:24892905 more ... GSK3B Human ethosuximide decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Ethosuximide results in decreased expression of GSK3B mRNA CTD PMID:26420483 GSK3B Human ethosuximide multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Ethosuximide inhibits the reaction [APP protein modified form results in increased expression of GSK3B mRNA] CTD PMID:26420483 GSK3B Human ethosuximide increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Ethosuximide results in increased phosphorylation of GSK3B protein CTD PMID:26420483 GSK3B Human ethosuximide multiple interactions EXP 6480464 DKK1 protein inhibits the reaction [Ethosuximide results in increased phosphorylation of GSK3B protein] CTD PMID:26420483 GSK3B Human ethyl methanesulfonate increases expression EXP 6480464 Ethyl Methanesulfonate results in increased expression of GSK3B mRNA CTD PMID:23649840 GSK3B Human etoposide multiple interactions ISO Gsk3b (Mus musculus) 6480464 BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein] CTD PMID:19408126 GSK3B Human etoposide increases activity ISO Gsk3b (Mus musculus) 6480464 [Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein and Etoposide results in increased activity of GSK3B protein CTD PMID:19408126 GSK3B Human eugenol increases expression EXP 6480464 Eugenol results in increased expression of GSK3B mRNA CTD PMID:17374397 GSK3B Human Evodiamine increases expression EXP 6480464 evodiamine results in increased expression of GSK3B protein CTD PMID:32425601 GSK3B Human excitatory amino acid agonist multiple interactions EXP 6480464 resveratrol inhibits the reaction [Excitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein] CTD PMID:24675465 GSK3B Human excitatory amino acid agonist multiple interactions ISO Gsk3b (Mus musculus) 6480464 Excitatory Amino Acid Agonists results in decreased expression of and results in decreased phosphorylation of GSK3B protein more ... CTD PMID:31586550 GSK3B Human excitatory amino acid agonist affects phosphorylation EXP 6480464 Excitatory Amino Acid Agonists affects the phosphorylation of GSK3B protein CTD PMID:24675465 GSK3B Human excitatory amino acid agonist multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Ascorbic Acid inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of GSK3B protein] more ... CTD PMID:24675465 GSK3B Human excitatory amino acid agonist increases response to substance ISO Gsk3b (Rattus norvegicus) 6480464 GSK3B protein results in increased susceptibility to Excitatory Amino Acid Agonists CTD PMID:24675465 GSK3B Human famotidine multiple interactions EXP 6480464 Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased phosphorylation of and results in increased activity of GSK3B protein] and Famotidine inhibits the reaction [Dizocilpine Maleate results in increased expression of GSK3B mRNA] CTD PMID:31563592 GSK3B Human fipronil decreases phosphorylation EXP 6480464 fipronil results in decreased phosphorylation of GSK3B protein CTD PMID:21296133 GSK3B Human fipronil affects response to substance EXP 6480464 GSK3B protein affects the susceptibility to fipronil CTD PMID:21296133 GSK3B Human fipronil multiple interactions EXP 6480464 kenpaullone inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein] and Lithium Chloride inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein] CTD PMID:21296133 GSK3B Human fisetin multiple interactions EXP 6480464 fisetin inhibits the reaction [Tobacco Smoke Pollution results in increased expression of GSK3B protein modified form] CTD PMID:31606474 GSK3B Human fluoxetine increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Fluoxetine results in increased expression of GSK3B protein CTD PMID:19359144 GSK3B Human folic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GSK3B gene CTD PMID:20938992 GSK3B Human folic acid decreases expression ISO Gsk3b (Mus musculus) 6480464 Folic Acid results in decreased expression of GSK3B mRNA CTD PMID:25629700 GSK3B Human folic acid increases expression ISO Gsk3b (Mus musculus) 6480464 Folic Acid results in increased expression of GSK3B mRNA CTD PMID:25006883 GSK3B Human formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of GSK3B mRNA CTD PMID:23649840 GSK3B Human FR900359 decreases phosphorylation EXP 6480464 FR900359 results in decreased phosphorylation of GSK3B protein CTD PMID:37730182 GSK3B Human fructose multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Fructose results in increased expression of and results in decreased phosphorylation of GSK3B protein CTD PMID:36049592 GSK3B Human fulvestrant multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 fulvestrant inhibits the reaction [gypenoside analog results in increased phosphorylation of GSK3B protein] and fulvestrant inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein] CTD PMID:24726523 GSK3B Human fulvestrant multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of GSK3B gene CTD PMID:31601247 GSK3B Human fulvestrant multiple interactions ISO Gsk3b (Mus musculus) 6480464 fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]] CTD PMID:23170834 GSK3B Human Fusaric acid increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Fusaric Acid results in increased phosphorylation of GSK3B protein CTD PMID:32156565 GSK3B Human galactose multiple interactions ISO Gsk3b (Mus musculus) 6480464 Galactose results in increased expression of and results in decreased phosphorylation of GSK3B protein and gentiopicroside analog inhibits the reaction [Galactose results in increased expression of and results in decreased phosphorylation of GSK3B protein] CTD PMID:36878094 GSK3B Human Gastrodin multiple interactions ISO Gsk3b (Mus musculus) 6480464 gastrodin inhibits the reaction [Glucose results in decreased phosphorylation of GSK3B protein] CTD PMID:33764184 GSK3B Human Gastrodin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 gastrodin inhibits the reaction [Glucose results in decreased phosphorylation of GSK3B protein] CTD PMID:33764184 GSK3B Human Gastrodin increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 gastrodin results in increased phosphorylation of GSK3B protein CTD PMID:33764184 GSK3B Human Gastrodin increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 gastrodin results in increased phosphorylation of GSK3B protein CTD PMID:33764184 GSK3B Human gefitinib decreases expression EXP 6480464 Gefitinib results in decreased expression of GSK3B protein modified form CTD PMID:30136359 GSK3B Human gemcitabine increases phosphorylation EXP 6480464 Gemcitabine results in increased phosphorylation of GSK3B protein CTD PMID:16570353 GSK3B Human Gentiopicrin multiple interactions ISO Gsk3b (Mus musculus) 6480464 gentiopicroside analog inhibits the reaction [Galactose results in increased expression of and results in decreased phosphorylation of GSK3B protein] CTD PMID:36878094 GSK3B Human geraniol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] CTD PMID:26165751 GSK3B Human gingerol multiple interactions EXP 6480464 gingerol inhibits the reaction [IL1B protein results in increased expression of GSK3B protein] more ... CTD PMID:18058799 and PMID:27645308 GSK3B Human gingerol increases response to substance ISO Gsk3b (Mus musculus) 6480464 GSK3B protein results in increased susceptibility to gingerol CTD PMID:26498061 GSK3B Human gingerol multiple interactions ISO Gsk3b (Mus musculus) 6480464 GSK3B protein promotes the reaction [gingerol results in decreased expression of CEBPA mRNA] more ... CTD PMID:26498061 GSK3B Human gingerol increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 gingerol results in increased phosphorylation of GSK3B protein CTD PMID:26498061 GSK3B Human gingerol increases expression EXP 6480464 gingerol results in increased expression of GSK3B protein CTD PMID:27645308 GSK3B Human ginsenoside Re increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 ginsenoside Re results in increased phosphorylation of GSK3B protein CTD PMID:17885204 GSK3B Human ginsenoside Rg1 multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein]] and ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein] CTD PMID:34859534 GSK3B Human ginsenoside Rg2 multiple interactions EXP 6480464 [[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose and dorsomorphin inhibits the reaction [ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] CTD PMID:22062806 GSK3B Human ginsenoside Rg2 increases phosphorylation EXP 6480464 ginsenoside Rg2 results in increased phosphorylation of GSK3B protein CTD PMID:22062806 GSK3B Human glucose multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GSK3B mRNA more ... CTD PMID:18004065 more ... GSK3B Human glucose decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:33764184 GSK3B Human glucose increases expression EXP 6480464 Glucose results in increased expression of GSK3B protein CTD PMID:35385194 GSK3B Human glucose increases expression ISO Gsk3b (Mus musculus) 6480464 Glucose results in increased expression of GSK3B protein CTD PMID:31483951 GSK3B Human glucose decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:26054749 and PMID:33764184 GSK3B Human glucose increases phosphorylation EXP 6480464 Glucose results in increased phosphorylation of GSK3B protein CTD PMID:23690508 GSK3B Human glucose decreases phosphorylation EXP 6480464 Glucose results in decreased phosphorylation of GSK3B protein CTD PMID:23954465 and PMID:35385194 GSK3B Human glucose multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Resveratrol results in increased phosphorylation of GSK3B protein] which results in increased uptake of Glucose more ... CTD PMID:22180358 more ... GSK3B Human glucose multiple interactions EXP 6480464 [[ginsenoside Rg2 results in increased phosphorylation of GSK3B protein] co-treated with [ginsenoside Rg2 results in increased expression of NR0B2 mRNA]] results in decreased chemical synthesis of Glucose more ... CTD PMID:21031461 more ... GSK3B Human glutathione increases abundance EXP 6480464 GSK3B protein mutant form results in increased abundance of Glutathione CTD PMID:25246272 GSK3B Human Glutathione ethyl ester increases phosphorylation EXP 6480464 S-ethyl glutathione results in increased phosphorylation of GSK3B protein CTD PMID:25246272 GSK3B Human Glutathione ethyl ester multiple interactions EXP 6480464 S-ethyl glutathione inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 GSK3B Human glycidol decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 glycidol results in decreased expression of GSK3B mRNA CTD PMID:33150645 GSK3B Human glycidol increases methylation ISO Gsk3b (Rattus norvegicus) 6480464 glycidol results in increased methylation of GSK3B promoter CTD PMID:33150595 GSK3B Human glycidyl methacrylate increases expression EXP 6480464 glycidyl methacrylate results in increased expression of GSK3B protein CTD PMID:36641056 GSK3B Human GSK2193874 multiple interactions ISO Gsk3b (Mus musculus) 6480464 GSK2193874 inhibits the reaction [Toluene 2 and 4-Diisocyanate results in increased phosphorylation of GSK3B protein] CTD PMID:30517707 GSK3B Human GSK690693 decreases phosphorylation EXP 6480464 GSK690693 results in decreased phosphorylation of GSK3B protein CTD PMID:31962201 GSK3B Human GSK690693 increases expression ISO Gsk3b (Mus musculus) 6480464 GSK690693 results in increased expression of GSK3B protein CTD PMID:35639300 GSK3B Human haloperidol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein] CTD PMID:16144542 GSK3B Human haloperidol increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Haloperidol results in increased expression of GSK3B mRNA and Haloperidol results in increased expression of GSK3B protein CTD PMID:16144542 and PMID:19359144 GSK3B Human hesperetin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein] CTD PMID:34922902 GSK3B Human hexachlorobenzene decreases activity ISO Gsk3b (Rattus norvegicus) 6480464 Hexachlorobenzene results in decreased activity of GSK3B protein CTD PMID:16679308 GSK3B Human hexachlorobenzene multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Hexachlorobenzene results in decreased activity of GSK3B protein] which results in decreased expression of CDH1 protein CTD PMID:16679308 GSK3B Human hexadecanoic acid multiple interactions EXP 6480464 Palmitic Acid inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] and Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein] CTD PMID:30362509 and PMID:38431059 GSK3B Human hexadecanoic acid multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 4-hydroxyisoleucine inhibits the reaction [Palmitic Acid inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]] more ... CTD PMID:25109277 and PMID:34774660 GSK3B Human hexadecanoic acid increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Palmitic Acid results in increased phosphorylation of GSK3B protein CTD PMID:34774660 GSK3B Human hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of GSK3B protein CTD PMID:20302854 and PMID:30296409 GSK3B Human hydrogen peroxide increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased expression of GSK3B mRNA and Hydrogen Peroxide results in increased expression of GSK3B protein CTD PMID:36518482 GSK3B Human hydrogen peroxide increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased phosphorylation of GSK3B protein CTD PMID:34047419 GSK3B Human hydrogen peroxide decreases phosphorylation EXP 6480464 Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein CTD PMID:31173752 GSK3B Human hydrogen peroxide decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein CTD PMID:23352507 GSK3B Human hydrogen peroxide multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [5-aminoisoquinolinone inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein]] more ... CTD PMID:23352507 more ... GSK3B Human hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of GSK3B mRNA CTD PMID:21179406 GSK3B Human hydrogen peroxide multiple interactions EXP 6480464 AKT1 protein modified form affects the reaction [ATM protein affects the reaction [N-(oxo-5 more ... CTD PMID:20302854 more ... GSK3B Human hydroquinone multiple interactions EXP 6480464 hydroquinone results in increased expression of and results in decreased phosphorylation of and results in increased activity of GSK3B protein more ... CTD PMID:28886972 GSK3B Human IC-87114 decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 IC 87114 results in decreased phosphorylation of GSK3B protein CTD PMID:16179367 GSK3B Human icariside II decreases phosphorylation EXP 6480464 baohuoside I results in decreased phosphorylation of GSK3B protein CTD PMID:25119583 GSK3B Human Icaritin multiple interactions ISO Gsk3b (Mus musculus) 6480464 icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein] CTD PMID:30731080 GSK3B Human Icaritin increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 icaritin results in increased phosphorylation of GSK3B protein CTD PMID:30731080 GSK3B Human indirubin-3'-monoxime decreases activity EXP 6480464 indirubin-3'-monoxime results in decreased activity of GSK3B protein CTD PMID:12534346 GSK3B Human indometacin increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Indomethacin results in increased expression of GSK3B mRNA CTD PMID:18299717 GSK3B Human iron atom multiple interactions EXP 6480464 [SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron] CTD PMID:19620254 GSK3B Human iron(0) multiple interactions EXP 6480464 [SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron] CTD PMID:19620254 GSK3B Human iron(2+) sulfate (anhydrous) increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 ferrous sulfate results in increased phosphorylation of GSK3B protein CTD PMID:19608791 GSK3B Human isoorientin decreases phosphorylation EXP 6480464 homoorientin results in decreased phosphorylation of GSK3B protein CTD PMID:34019859 GSK3B Human isoprenaline multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-((2-piperidin-1-ylethyl)thio)quinazolin-4(3H)-one inhibits the reaction [Isoproterenol results in decreased phosphorylation of GSK3B protein] more ... CTD PMID:15951400 more ... GSK3B Human isoprenaline increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Isoproterenol results in increased phosphorylation of GSK3B protein CTD PMID:31009642 GSK3B Human isoprenaline multiple interactions ISO Gsk3b (Mus musculus) 6480464 plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] and Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:31009642 GSK3B Human isoprenaline increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Isoproterenol results in increased phosphorylation of GSK3B protein CTD PMID:15951400 more ... GSK3B Human isoprenaline decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Isoproterenol results in decreased phosphorylation of GSK3B protein CTD PMID:18806606 GSK3B Human isorhapontigenin multiple interactions EXP 6480464 [sodium bichromate co-treated with isorhapontigenin] results in increased phosphorylation of GSK3B protein CTD PMID:37619952 GSK3B Human ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of GSK3B protein CTD PMID:32959892 GSK3B Human kaempferol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [kaempferol co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein] more ... CTD PMID:30497708 and PMID:36940862 GSK3B Human kahweol increases phosphorylation EXP 6480464 kahweol results in increased phosphorylation of GSK3B protein CTD PMID:27424123 GSK3B Human kahweol decreases phosphorylation EXP 6480464 kahweol results in decreased phosphorylation of GSK3B protein CTD PMID:30205135 GSK3B Human kainic acid decreases activity ISO Gsk3b (Mus musculus) 6480464 Kainic Acid results in decreased activity of GSK3B protein CTD PMID:18619545 GSK3B Human kainic acid decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Kainic Acid results in decreased phosphorylation of GSK3B protein CTD PMID:25453207 GSK3B Human kainic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 4-benzyl-2-methyl-1 more ... CTD PMID:25453207 GSK3B Human kenpaullone multiple interactions EXP 6480464 kenpaullone inhibits the reaction [fipronil results in decreased phosphorylation of GSK3B protein] CTD PMID:21296133 GSK3B Human kenpaullone decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 kenpaullone results in decreased phosphorylation of GSK3B protein CTD PMID:17993264 GSK3B Human kenpaullone decreases activity EXP 6480464 kenpaullone results in decreased activity of GSK3B protein CTD PMID:12534346 and PMID:21111724 GSK3B Human ketamine decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Ketamine results in decreased phosphorylation of GSK3B protein CTD PMID:17952604 GSK3B Human ketamine increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Ketamine results in increased phosphorylation of GSK3B protein CTD PMID:36334642 GSK3B Human ketamine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Chir 99021 inhibits the reaction [Ketamine results in increased phosphorylation of GSK3B protein] CTD PMID:36334642 GSK3B Human KT 5823 decreases activity EXP 6480464 KT 5823 results in decreased activity of GSK3B protein CTD PMID:12534346 GSK3B Human L-ascorbic acid decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Ascorbic Acid results in decreased expression of GSK3B mRNA CTD PMID:15372504 GSK3B Human L-ascorbic acid multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Ascorbic Acid inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of GSK3B protein] CTD PMID:24675465 GSK3B Human L-glutamic acid multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein]] more ... CTD PMID:32092300 GSK3B Human L-methionine multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of GSK3B gene CTD PMID:20938992 GSK3B Human L-serine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [LAMC1 protein modified form co-treated with ANGPT1 protein co-treated with Serine] inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein] and Serine inhibits the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein] CTD PMID:30476904 GSK3B Human lead diacetate increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 lead acetate results in increased phosphorylation of GSK3B protein CTD PMID:27012722 GSK3B Human lead diacetate increases expression ISO Gsk3b (Mus musculus) 6480464 lead acetate results in increased expression of GSK3B protein CTD PMID:37385299 GSK3B Human lead diacetate multiple interactions ISO Gsk3b (Mus musculus) 6480464 3 more ... CTD PMID:37385299 and PMID:37436718 GSK3B Human lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of GSK3B mRNA CTD PMID:38568856 GSK3B Human lead nitrate multiple interactions ISO Gsk3b (Mus musculus) 6480464 [lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein and icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein] CTD PMID:30731080 GSK3B Human lead(0) affects splicing EXP 6480464 Lead affects the splicing of GSK3B mRNA CTD PMID:28903495 GSK3B Human lead(0) multiple interactions ISO Gsk3b (Mus musculus) 6480464 [lead acetate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein more ... CTD PMID:30731080 and PMID:37436718 GSK3B Human lipoic acid increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Thioctic Acid results in increased phosphorylation of GSK3B protein CTD PMID:19879292 GSK3B Human lipoic acid multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [amyloid beta-protein (25-35) results in decreased phosphorylation of GSK3B protein] and Thioctic Acid inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of GSK3B protein] CTD PMID:34133789 GSK3B Human lipoic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Dietary Fats results in increased expression of GSK3B mRNA] CTD PMID:27260466 GSK3B Human lipopolysaccharide decreases expression ISO Gsk3b (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of GSK3B protein modified form CTD PMID:23170834 GSK3B Human lipopolysaccharide decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Lipopolysaccharides results in decreased phosphorylation of GSK3B protein CTD PMID:34874107 and PMID:37815058 GSK3B Human lipopolysaccharide decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lipopolysaccharides results in decreased phosphorylation of GSK3B protein CTD PMID:34859534 GSK3B Human lipopolysaccharide multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ginsenoside Rg1 inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein]] more ... CTD PMID:18047562 and PMID:34859534 GSK3B Human lipopolysaccharide increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased phosphorylation of GSK3B protein CTD PMID:18047562 GSK3B Human lipopolysaccharide multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Drugs more ... CTD PMID:23170834 more ... GSK3B Human liraglutide multiple interactions EXP 6480464 Liraglutide inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein] and Wortmannin inhibits the reaction [Liraglutide inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of GSK3B protein]] CTD PMID:31173752 GSK3B Human lithium atom multiple interactions EXP 6480464 Lithium inhibits the reaction [GSK3B protein binds to TP53 protein] more ... CTD PMID:10998351 more ... GSK3B Human lithium atom decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in decreased phosphorylation of GSK3B protein CTD PMID:25433145 GSK3B Human lithium atom increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in increased expression of GSK3B mRNA and Lithium results in increased expression of GSK3B protein CTD PMID:18296634 and PMID:19359144 GSK3B Human lithium atom multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:15950778 and PMID:21711903 GSK3B Human lithium atom increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in increased phosphorylation of GSK3B protein CTD PMID:18296634 GSK3B Human lithium atom decreases activity ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in decreased activity of GSK3B protein CTD PMID:16288908 GSK3B Human lithium atom increases phosphorylation EXP 6480464 Lithium results in increased phosphorylation of GSK3B protein CTD PMID:15475000 and PMID:19440698 GSK3B Human lithium atom multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Lithium results in decreased activity of GSK3B protein] which results in increased activity of MTOR protein more ... CTD PMID:17921520 more ... GSK3B Human lithium atom decreases activity ISO Gsk3b (Mus musculus) 6480464 Lithium results in decreased activity of GSK3B protein CTD PMID:19621015 GSK3B Human lithium atom decreases activity EXP 6480464 Lithium results in decreased activity of GSK3B protein CTD PMID:10998351 GSK3B Human lithium chloride multiple interactions ISO Gsk3b (Mus musculus) 6480464 [[Lithium Chloride results in increased phosphorylation of and results in decreased activity of GSK3B protein] which results in increased localization of CTNNB1 protein] which results in increased expression of GIP mRNA more ... CTD PMID:19440036 more ... GSK3B Human lithium chloride increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Lithium Chloride results in increased phosphorylation of GSK3B protein CTD PMID:27018151 GSK3B Human lithium chloride increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lithium Chloride results in increased phosphorylation of GSK3B protein CTD PMID:23651617 more ... GSK3B Human lithium chloride increases expression EXP 6480464 Lithium Chloride results in increased expression of GSK3B protein modified form CTD PMID:22944069 and PMID:30703377 GSK3B Human lithium chloride decreases activity EXP 6480464 Lithium Chloride results in decreased activity of GSK3B protein CTD PMID:19101580 more ... GSK3B Human lithium chloride increases phosphorylation EXP 6480464 Lithium Chloride results in increased phosphorylation of GSK3B protein CTD PMID:18830594 more ... GSK3B Human lithium chloride decreases activity ISO Gsk3b (Mus musculus) 6480464 Lithium Chloride results in decreased activity of GSK3B protein CTD PMID:15364539 more ... GSK3B Human lithium chloride decreases activity ISO Gsk3b (Rattus norvegicus) 6480464 Lithium Chloride results in decreased activity of GSK3B protein CTD PMID:15247282 and PMID:18972237 GSK3B Human lithium chloride increases stability ISO Gsk3b (Mus musculus) 6480464 Lithium Chloride results in increased stability of GSK3B protein CTD PMID:19448134 GSK3B Human lithium chloride affects phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lithium Chloride affects the phosphorylation of GSK3B protein CTD PMID:21364661 GSK3B Human lithium chloride decreases phosphorylation EXP 6480464 Lithium Chloride results in decreased phosphorylation of GSK3B protein CTD PMID:20093106 GSK3B Human lithium chloride multiple interactions EXP 6480464 [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of and results in increased phosphorylation of CTNNB1 protein more ... CTD PMID:15753396 more ... GSK3B Human lithium chloride decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Lithium Chloride results in decreased expression of GSK3B mRNA CTD PMID:18932008 GSK3B Human lithium chloride multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [[Lithium Chloride results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein] which affects the expression of GJA1 protein more ... CTD PMID:12813129 more ... GSK3B Human lithium hydride multiple interactions EXP 6480464 Lithium inhibits the reaction [GSK3B protein binds to TP53 protein] more ... CTD PMID:10998351 more ... GSK3B Human lithium hydride decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in decreased phosphorylation of GSK3B protein CTD PMID:25433145 GSK3B Human lithium hydride decreases activity ISO Gsk3b (Mus musculus) 6480464 Lithium results in decreased activity of GSK3B protein CTD PMID:19621015 GSK3B Human lithium hydride multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:15950778 and PMID:21711903 GSK3B Human lithium hydride increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in increased phosphorylation of GSK3B protein CTD PMID:18296634 GSK3B Human lithium hydride decreases activity ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in decreased activity of GSK3B protein CTD PMID:16288908 GSK3B Human lithium hydride multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Lithium results in decreased activity of GSK3B protein] which results in increased activity of MTOR protein more ... CTD PMID:17921520 more ... GSK3B Human lithium hydride increases phosphorylation EXP 6480464 Lithium results in increased phosphorylation of GSK3B protein CTD PMID:15475000 and PMID:19440698 GSK3B Human lithium hydride increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Lithium results in increased expression of GSK3B mRNA and Lithium results in increased expression of GSK3B protein CTD PMID:18296634 and PMID:19359144 GSK3B Human lithium hydride decreases activity EXP 6480464 Lithium results in decreased activity of GSK3B protein CTD PMID:10998351 GSK3B Human lithocholic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 Lithocholic Acid results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:20512997 GSK3B Human Lobetyolin multiple interactions EXP 6480464 AKT1 protein inhibits the reaction [lobetyolin results in decreased phosphorylation of GSK3B protein] CTD PMID:34075790 GSK3B Human Lobetyolin decreases phosphorylation EXP 6480464 lobetyolin results in decreased phosphorylation of GSK3B protein CTD PMID:34075790 GSK3B Human loliolide increases phosphorylation EXP 6480464 loliolide results in increased phosphorylation of GSK3B protein CTD PMID:31601058 GSK3B Human lonafarnib multiple interactions EXP 6480464 [Bortezomib co-treated with lonafarnib] results in decreased expression of GSK3B protein modified form CTD PMID:16118318 GSK3B Human losartan multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Losartan inhibits the reaction [AGT protein modified form results in increased phosphorylation of GSK3B protein] CTD PMID:22982863 GSK3B Human lovastatin decreases phosphorylation EXP 6480464 Lovastatin results in decreased phosphorylation of GSK3B protein CTD PMID:17234346 GSK3B Human lovastatin increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Lovastatin results in increased phosphorylation of GSK3B protein CTD PMID:19741129 GSK3B Human lupeol affects binding ISO Gsk3b (Rattus norvegicus) 6480464 lupeol binds to GSK3B protein CTD PMID:18222664 GSK3B Human LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[oxyphylla A co-treated with APP protein] results in increased phosphorylation of GSK3B protein] more ... CTD PMID:14750165 more ... GSK3B Human LY294002 decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein CTD PMID:34283317 and PMID:34455488 GSK3B Human LY294002 decreases phosphorylation EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein CTD PMID:21821001 more ... GSK3B Human LY294002 affects response to substance ISO Gsk3b (Mus musculus) 6480464 GSK3B mRNA affects the susceptibility to 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one CTD PMID:21832246 GSK3B Human LY294002 decreases response to substance EXP 6480464 GSK3B results in decreased susceptibility to 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one CTD PMID:21821001 GSK3B Human LY294002 decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein CTD PMID:16179367 GSK3B Human LY294002 increases activity EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased activity of GSK3B protein CTD PMID:15753396 GSK3B Human LY294002 multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of GSK3B protein] more ... CTD PMID:17952604 more ... GSK3B Human LY294002 multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Drugs more ... CTD PMID:15845746 more ... GSK3B Human lysophosphatidylethanolamine multiple interactions EXP 6480464 [lysophosphatidylethanolamine analog co-treated with cobaltous chloride] results in increased phosphorylation of GSK3B protein CTD PMID:25125499 GSK3B Human magnesium atom multiple interactions EXP 6480464 Magnesium affects the reaction [Lithium results in decreased activity of GSK3B protein] CTD PMID:10998351 GSK3B Human Magnolol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 magnolol inhibits the reaction [Monocrotaline results in increased phosphorylation of GSK3B protein] CTD PMID:30466619 GSK3B Human malathion increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Malathion results in increased expression of GSK3B mRNA CTD PMID:25449180 GSK3B Human malvidin multiple interactions ISO Gsk3b (Mus musculus) 6480464 malvidin promotes the reaction [[endotoxin and Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein] CTD PMID:23755222 GSK3B Human mancozeb multiple interactions ISO Gsk3b (Mus musculus) 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 GSK3B Human maneb multiple interactions ISO Gsk3b (Mus musculus) 6480464 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 GSK3B Human manganese(II) chloride increases activity ISO Gsk3b (Rattus norvegicus) 6480464 manganese chloride results in increased activity of GSK3B protein CTD PMID:20937724 GSK3B Human manganese(II) chloride multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride results in decreased phosphorylation of GSK3B protein] more ... CTD PMID:20937724 and PMID:24464479 GSK3B Human manganese(II) chloride decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 manganese chloride results in decreased phosphorylation of GSK3B protein CTD PMID:20937724 GSK3B Human melatonin multiple interactions ISO Gsk3b (Mus musculus) 6480464 Melatonin inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form] CTD PMID:15842767 GSK3B Human melatonin decreases expression EXP 6480464 Melatonin results in decreased expression of GSK3B protein CTD PMID:37755321 GSK3B Human melatonin multiple interactions EXP 6480464 MIR532 promotes the reaction [Melatonin results in decreased expression of GSK3B protein] CTD PMID:37755321 GSK3B Human melatonin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Aluminum Chloride results in increased expression of GSK3B protein modified form] more ... CTD PMID:31809235 and PMID:35526705 GSK3B Human memantine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein]] and Memantine analog inhibits the reaction [Glutamic Acid results in decreased phosphorylation of and results in increased activity of GSK3B protein] CTD PMID:32092300 GSK3B Human menadione increases expression EXP 6480464 Vitamin K 3 results in increased expression of GSK3B protein CTD PMID:31238027 GSK3B Human mercury dichloride multiple interactions ISO Gsk3b (Mus musculus) 6480464 GSK3B protein promotes the reaction [Mercuric Chloride results in increased activity of BAX protein] and GSK3B protein promotes the reaction [Mercuric Chloride results in increased cleavage of CASP3 protein] CTD PMID:22785175 GSK3B Human metformin increases phosphorylation EXP 6480464 Metformin results in increased phosphorylation of GSK3B protein CTD PMID:21054339 and PMID:26835874 GSK3B Human metformin multiple interactions ISO Gsk3b (Mus musculus) 6480464 Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] CTD PMID:34649470 GSK3B Human metformin decreases expression EXP 6480464 Metformin results in decreased expression of GSK3B protein modified form CTD PMID:33838154 GSK3B Human metformin multiple interactions EXP 6480464 AKT1 protein modified form inhibits the reaction [Metformin promotes the reaction [plantamajoside results in decreased phosphorylation of GSK3B protein]] more ... CTD PMID:30928401 more ... GSK3B Human metformin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein] and Metformin inhibits the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein] CTD PMID:30742852 and PMID:31877369 GSK3B Human methamphetamine multiple interactions ISO Gsk3b (Mus musculus) 6480464 Rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of GSK3B protein] more ... CTD PMID:29981415 and PMID:32278788 GSK3B Human methamphetamine affects phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Methamphetamine affects the phosphorylation of GSK3B protein CTD PMID:35863504 GSK3B Human methamphetamine increases expression ISO Gsk3b (Mus musculus) 6480464 Methamphetamine results in increased expression of GSK3B protein modified form CTD PMID:32278788 GSK3B Human methamphetamine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein] and Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein CTD PMID:30742852 GSK3B Human methamphetamine affects phosphorylation EXP 6480464 Methamphetamine affects the phosphorylation of GSK3B protein CTD PMID:31270305 GSK3B Human methamphetamine multiple interactions EXP 6480464 Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of GSK3B protein] CTD PMID:31270305 GSK3B Human methamphetamine decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Methamphetamine results in decreased phosphorylation of GSK3B protein CTD PMID:30367931 GSK3B Human methamphetamine increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Methamphetamine results in increased phosphorylation of GSK3B protein CTD PMID:29981415 GSK3B Human methapyrilene increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Methapyrilene results in increased expression of GSK3B mRNA CTD PMID:16393664 GSK3B Human methotrexate multiple interactions EXP 6480464 Methotrexate promotes the reaction [6-bromoindirubin-3'-oxime results in increased phosphorylation of GSK3B protein] CTD PMID:19727391 GSK3B Human methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of GSK3B mRNA CTD PMID:23649840 GSK3B Human methylglyoxal decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Pyruvaldehyde results in decreased phosphorylation of GSK3B protein CTD PMID:34455488 GSK3B Human methylglyoxal multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Phosphocreatine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of GSK3B protein] CTD PMID:34455488 GSK3B Human methylmercury chloride increases expression ISO Gsk3b (Mus musculus) 6480464 methylmercuric chloride results in increased expression of GSK3B mRNA CTD PMID:20061341 GSK3B Human methylmercury chloride decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 methylmercuric chloride results in decreased phosphorylation of GSK3B protein CTD PMID:29258870 GSK3B Human methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of GSK3B mRNA CTD PMID:28001369 GSK3B Human methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of GSK3B mRNA CTD PMID:28001369 GSK3B Human methylmercury chloride multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 methylmercuric chloride results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:28821999 GSK3B Human methylmercury chloride increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 methylmercuric chloride results in increased phosphorylation of GSK3B protein CTD PMID:28736149 GSK3B Human methylseleninic acid multiple interactions EXP 6480464 methylselenic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein] CTD PMID:17339365 GSK3B Human methylseleninic acid decreases phosphorylation EXP 6480464 methylselenic acid results in decreased phosphorylation of GSK3B protein CTD PMID:17339365 GSK3B Human microcystin-LR increases phosphorylation EXP 6480464 cyanoginosin LR results in increased phosphorylation of GSK3B protein CTD PMID:20421190 more ... GSK3B Human microcystin-LR increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 cyanoginosin LR results in increased phosphorylation of GSK3B protein CTD PMID:32073747 GSK3B Human microcystin-LR multiple interactions ISO Gsk3b (Mus musculus) 6480464 cyanoginosin LR results in increased expression of and results in increased phosphorylation of GSK3B protein and cyanoginosin LR results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:28984034 and PMID:36115647 GSK3B Human microcystin-LR multiple interactions EXP 6480464 cyanoginosin LR promotes the reaction [INS protein results in increased phosphorylation of and results in decreased activity of GSK3B protein] more ... CTD PMID:28984034 more ... GSK3B Human mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Progesterone results in increased phosphorylation of GSK3B protein] CTD PMID:16882987 GSK3B Human mitomycin C increases phosphorylation EXP 6480464 Mitomycin results in increased phosphorylation of GSK3B protein CTD PMID:34624459 GSK3B Human mitomycin C multiple interactions EXP 6480464 baicalein inhibits the reaction [Mitomycin results in increased phosphorylation of GSK3B protein] more ... CTD PMID:34624459 GSK3B Human Mizoribine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 mizoribine inhibits the reaction [Puromycin Aminonucleoside results in increased phosphorylation of GSK3B protein] CTD PMID:20502051 GSK3B Human MK-2206 multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 MK 2206 inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of GSK3B protein] and MK 2206 promotes the reaction [PHLDA3 protein promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased phosphorylation of GSK3B protein]] CTD PMID:29669060 and PMID:34351043 GSK3B Human MK-2206 multiple interactions EXP 6480464 MK 2206 inhibits the reaction [cyanoginosin LR results in increased expression of and results in increased phosphorylation of GSK3B protein] more ... CTD PMID:34758370 more ... GSK3B Human mono(2-ethylhexyl) phthalate multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased phosphorylation of GSK3B protein] CTD PMID:28526321 GSK3B Human mono(2-ethylhexyl) phthalate decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of GSK3B protein CTD PMID:37364752 GSK3B Human mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [mono-(2-ethylhexyl)phthalate results in decreased activity of INS protein] which results in decreased phosphorylation of GSK3B protein more ... CTD PMID:31228551 GSK3B Human mono(2-ethylhexyl) phthalate decreases phosphorylation EXP 6480464 mono-(2-ethylhexyl)phthalate results in decreased phosphorylation of GSK3B protein CTD PMID:31228551 GSK3B Human monocrotaline multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 magnolol inhibits the reaction [Monocrotaline results in increased phosphorylation of GSK3B protein] CTD PMID:30466619 GSK3B Human monocrotaline increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Monocrotaline results in increased phosphorylation of GSK3B protein CTD PMID:30466619 GSK3B Human monodansylcadaverine decreases expression EXP 6480464 monodansylcadaverine results in decreased expression of GSK3B protein CTD PMID:16170020 GSK3B Human morin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of GSK3B protein] and morin inhibits the reaction [Diethylnitrosamine results in increased expression of GSK3B protein modified form] CTD PMID:19931519 and PMID:26767949 GSK3B Human morphine increases expression ISO Gsk3b (Mus musculus) 6480464 Morphine results in increased expression of GSK3B protein modified form CTD PMID:20600172 GSK3B Human morphine multiple interactions ISO Gsk3b (Mus musculus) 6480464 Naloxone inhibits the reaction [Morphine results in increased expression of GSK3B protein modified form] CTD PMID:20600172 GSK3B Human mycophenolic acid multiple interactions EXP 6480464 Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GSK3B protein] CTD PMID:20302854 GSK3B Human N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Caffeine results in increased phosphorylation of GSK3B protein] CTD PMID:21229324 GSK3B Human N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [oxyphylla A results in increased phosphorylation of GSK3B protein] CTD PMID:39233265 GSK3B Human N-acetyl-L-cysteine multiple interactions ISO Gsk3b (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein] and Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of GSK3B protein] CTD PMID:18569013 and PMID:19126599 GSK3B Human N-acetyl-L-cysteine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein] CTD PMID:27658547 GSK3B Human N-acetyl-L-cysteine multiple interactions EXP 6480464 [Acetylcysteine co-treated with Chlorpyrifos] results in increased activity of GSK3B protein more ... CTD PMID:24968063 more ... GSK3B Human N-acetylsphingosine decreases phosphorylation EXP 6480464 N-acetylsphingosine results in decreased phosphorylation of GSK3B protein CTD PMID:21821001 GSK3B Human N-acetylsphingosine decreases expression EXP 6480464 N-acetylsphingosine results in decreased expression of GSK3B protein modified form CTD PMID:24420784 GSK3B Human N-acetylsphingosine multiple interactions EXP 6480464 GSK3B mutant form inhibits the reaction [N-acetylsphingosine results in increased expression of LGALS3 protein] CTD PMID:21821001 GSK3B Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]] CTD PMID:26990689 GSK3B Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSK3B protein modified form CTD PMID:30703377 GSK3B Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases phosphorylation EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of GSK3B protein CTD PMID:24085292 GSK3B Human N-ethyl-N-nitrosourea decreases expression ISO Gsk3b (Mus musculus) 6480464 Ethylnitrosourea results in decreased expression of GSK3B protein CTD PMID:28549617 GSK3B Human N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of and results in increased activity of GSK3B protein more ... CTD PMID:20064577 more ... GSK3B Human N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of GSK3B mRNA and 1-Methyl-4-phenylpyridinium results in increased expression of GSK3B protein CTD PMID:28484287 and PMID:30302821 GSK3B Human N-methyl-4-phenylpyridinium multiple interactions ISO Gsk3b (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium promotes the reaction [ABL1 protein binds to and results in increased phosphorylation of and results in increased activity of GSK3B protein] more ... CTD PMID:30165626 and PMID:32763437 GSK3B Human N-methyl-4-phenylpyridinium decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in decreased phosphorylation of GSK3B protein CTD PMID:22891246 GSK3B Human N-methyl-4-phenylpyridinium increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in increased phosphorylation of GSK3B protein CTD PMID:20064577 GSK3B Human N-methyl-4-phenylpyridinium multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in decreased activity of GSK3B protein more ... CTD PMID:20064577 more ... GSK3B Human N-methyl-D-aspartic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 N-Methylaspartate inhibits the reaction [gelsenicine results in increased phosphorylation of GSK3B protein] CTD PMID:34389372 GSK3B Human N-methyl-N-nitrosourea multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein and Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein] CTD PMID:25164625 GSK3B Human N-nitrosodiethylamine multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of GSK3B protein and CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of GSK3B protein] CTD PMID:20583210 and PMID:30826251 GSK3B Human N-nitrosodiethylamine affects phosphorylation ISO Gsk3b (Mus musculus) 6480464 Diethylnitrosamine affects the phosphorylation of GSK3B protein CTD PMID:24535843 GSK3B Human N-nitrosodiethylamine increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased phosphorylation of GSK3B protein CTD PMID:21554863 GSK3B Human N-nitrosodiethylamine increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of GSK3B protein modified form CTD PMID:19931519 GSK3B Human N-nitrosodiethylamine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 5 more ... CTD PMID:19931519 and PMID:21554863 GSK3B Human N-nitrosodiethylamine increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Diethylnitrosamine results in increased phosphorylation of GSK3B protein CTD PMID:20583210 GSK3B Human N-phosphocreatine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Phosphocreatine inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] more ... CTD PMID:34455488 GSK3B Human NAD zwitterion increases abundance EXP 6480464 GSK3B protein mutant form results in increased abundance of NAD metabolite CTD PMID:25246272 GSK3B Human NAD zwitterion multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:25536389 GSK3B Human NAD(+) increases abundance EXP 6480464 GSK3B protein mutant form results in increased abundance of NAD metabolite CTD PMID:25246272 GSK3B Human NAD(+) multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:25536389 GSK3B Human NADP zwitterion increases abundance EXP 6480464 GSK3B protein mutant form results in increased abundance of NADP metabolite CTD PMID:25246272 GSK3B Human NADP(+) increases abundance EXP 6480464 GSK3B protein mutant form results in increased abundance of NADP metabolite CTD PMID:25246272 GSK3B Human naloxone multiple interactions ISO Gsk3b (Mus musculus) 6480464 Naloxone inhibits the reaction [Morphine results in increased expression of GSK3B protein modified form] CTD PMID:20600172 GSK3B Human nickel dichloride multiple interactions EXP 6480464 [nickel chloride results in increased phosphorylation of AKT1 protein] which results in decreased activity of and results in increased phosphorylation of GSK3B protein and nickel chloride promotes the reaction [Tretinoin results in increased phosphorylation of GSK3B protein] CTD PMID:21837363 and PMID:25614230 GSK3B Human nickel dichloride affects expression ISO Gsk3b (Rattus norvegicus) 6480464 nickel chloride affects the expression of GSK3B mRNA CTD PMID:22546817 GSK3B Human nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of GSK3B mRNA CTD PMID:17374397 GSK3B Human niclosamide decreases expression EXP 6480464 Niclosamide results in decreased expression of GSK3B mRNA CTD PMID:22576131 GSK3B Human niclosamide increases phosphorylation EXP 6480464 Niclosamide results in increased phosphorylation of GSK3B protein CTD PMID:35115509 GSK3B Human niclosamide decreases phosphorylation EXP 6480464 Niclosamide results in decreased phosphorylation of GSK3B protein CTD PMID:30143678 GSK3B Human nicotine multiple interactions EXP 6480464 [Nicotine results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein CTD PMID:12511591 GSK3B Human nicotine multiple interactions ISO Gsk3b (Mus musculus) 6480464 Carbon Tetrachloride inhibits the reaction [Nicotine results in decreased expression of GSK3B mRNA] more ... CTD PMID:31945395 more ... GSK3B Human nicotine increases expression ISO Gsk3b (Mus musculus) 6480464 Nicotine results in increased expression of GSK3B mRNA CTD PMID:31945395 and PMID:35411647 GSK3B Human nicotine decreases expression ISO Gsk3b (Mus musculus) 6480464 Nicotine results in decreased expression of GSK3B mRNA and Nicotine results in decreased expression of GSK3B protein CTD PMID:33640489 and PMID:35411647 GSK3B Human nimesulide decreases activity EXP 6480464 nimesulide results in decreased activity of GSK3B protein CTD PMID:16331303 GSK3B Human nitrofurazone affects binding ISO Gsk3b (Rattus norvegicus) 6480464 Nitrofurazone binds to GSK3B protein CTD PMID:18222664 GSK3B Human nitroprusside multiple interactions ISO Gsk3b (Mus musculus) 6480464 Nitroprusside results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:29353218 GSK3B Human nitroprusside multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Nitroprusside results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:29353218 GSK3B Human nordihydroguaiaretic acid increases phosphorylation ISO Gsk3b (Rattus norvegicus) 329955565 NDGA increases phosphorylation in liver of high fructose fed rats RGD GSK3B Human notoginsenoside R1 multiple interactions ISO Gsk3b (Mus musculus) 6480464 fulvestrant inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]] more ... CTD PMID:23170834 GSK3B Human notoginsenoside R1 increases expression ISO Gsk3b (Rattus norvegicus) 6480464 notoginsenoside R1 results in increased expression of GSK3B protein modified form CTD PMID:24720662 GSK3B Human ochratoxin A increases phosphorylation EXP 6480464 ochratoxin A results in increased phosphorylation of GSK3B protein CTD PMID:25002221 GSK3B Human okadaic acid affects phosphorylation ISO Gsk3b (Mus musculus) 6480464 Okadaic Acid affects the phosphorylation of GSK3B protein CTD PMID:27050422 GSK3B Human okadaic acid increases phosphorylation EXP 6480464 Okadaic Acid results in increased phosphorylation of GSK3B protein CTD PMID:26836014 GSK3B Human okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of GSK3B protein and Okadaic Acid results in increased expression of GSK3B protein modified form CTD PMID:21715663 GSK3B Human okadaic acid multiple interactions EXP 6480464 [5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form] more ... CTD PMID:21715663 and PMID:23292070 GSK3B Human okadaic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]] more ... CTD PMID:27050422 GSK3B Human olanzapine increases phosphorylation EXP 6480464 olanzapine results in increased phosphorylation of GSK3B protein CTD PMID:19440698 GSK3B Human olanzapine decreases expression EXP 6480464 Olanzapine results in decreased expression of GSK3B mRNA CTD PMID:31563592 GSK3B Human olanzapine multiple interactions EXP 6480464 Olanzapine inhibits the reaction [Dizocilpine Maleate results in increased expression of GSK3B mRNA] CTD PMID:31563592 GSK3B Human oleic acid decreases phosphorylation EXP 6480464 Oleic Acid results in decreased phosphorylation of GSK3B protein CTD PMID:25536389 GSK3B Human oleic acid multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:25536389 GSK3B Human oleuropein multiple interactions ISO Gsk3b (Mus musculus) 6480464 oleuropein inhibits the reaction [Rotenone results in decreased expression of and results in decreased phosphorylation of GSK3B protein] CTD PMID:36774383 GSK3B Human omethoate multiple interactions EXP 6480464 1 more ... CTD PMID:31574243 GSK3B Human omethoate increases phosphorylation EXP 6480464 dimethoxon results in increased phosphorylation of GSK3B protein CTD PMID:31574243 GSK3B Human oxaliplatin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of GSK3B mRNA CTD PMID:25729387 GSK3B Human ozone multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of GSK3B mRNA more ... CTD PMID:33217375 more ... GSK3B Human ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of GSK3B mRNA CTD PMID:35430440 GSK3B Human ozone increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Ozone results in increased phosphorylation of GSK3B protein CTD PMID:33146391 GSK3B Human paclitaxel increases phosphorylation EXP 6480464 Paclitaxel results in increased phosphorylation of GSK3B protein CTD PMID:19426673 GSK3B Human paclitaxel multiple interactions EXP 6480464 [Paclitaxel co-treated with FV-429 compound] inhibits the reaction [Oxygen deficiency results in increased phosphorylation of GSK3B protein] and [Paclitaxel co-treated with FV-429 compound] promotes the reaction [Oxygen deficiency results in increased expression of GSK3B protein] CTD PMID:34648812 GSK3B Human palmatine multiple interactions ISO Gsk3b (Mus musculus) 6480464 palmatine inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of GSK3B protein] CTD PMID:37815058 GSK3B Human Panaxadiol increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 panaxadiol results in increased phosphorylation of GSK3B protein CTD PMID:32535096 GSK3B Human paracetamol increases expression ISO Gsk3b (Mus musculus) 6480464 Acetaminophen results in increased expression of GSK3B protein modified form CTD PMID:19679878 GSK3B Human paracetamol increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Acetaminophen results in increased phosphorylation of GSK3B protein CTD PMID:22687999 more ... GSK3B Human paracetamol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 morin inhibits the reaction [Acetaminophen results in decreased phosphorylation of GSK3B protein] CTD PMID:26767949 GSK3B Human paracetamol decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Acetaminophen results in decreased phosphorylation of GSK3B protein CTD PMID:26767949 GSK3B Human paracetamol multiple interactions ISO Gsk3b (Mus musculus) 6480464 coenzyme Q10 promotes the reaction [Acetaminophen results in increased phosphorylation of GSK3B protein] more ... CTD PMID:22687999 more ... GSK3B Human paracetamol affects expression ISO Gsk3b (Rattus norvegicus) 6480464 Acetaminophen affects the expression of GSK3B mRNA CTD PMID:16701773 GSK3B Human paraquat multiple interactions ISO Gsk3b (Mus musculus) 6480464 Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein] and Paraquat results in increased expression of and results in increased phosphorylation of GSK3B protein CTD PMID:22292029 and PMID:30171970 GSK3B Human paraquat decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Paraquat results in decreased phosphorylation of GSK3B protein CTD PMID:34048864 and PMID:36394833 GSK3B Human paraquat decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Paraquat results in decreased phosphorylation of GSK3B protein CTD PMID:30171970 GSK3B Human paraquat increases phosphorylation EXP 6480464 Paraquat results in increased phosphorylation of GSK3B protein CTD PMID:30205152 GSK3B Human paraquat multiple interactions EXP 6480464 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]] more ... CTD PMID:28414160 and PMID:30171970 GSK3B Human paraquat increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Paraquat results in increased phosphorylation of GSK3B protein CTD PMID:24634145 GSK3B Human paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of GSK3B protein CTD PMID:28414160 GSK3B Human parecoxib increases expression EXP 6480464 parecoxib results in increased expression of GSK3B protein CTD PMID:35917206 GSK3B Human parecoxib decreases expression EXP 6480464 parecoxib results in decreased expression of GSK3B protein modified form CTD PMID:35917206 GSK3B Human pentetrazol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Sitagliptin Phosphate inhibits the reaction [Pentylenetetrazole results in decreased phosphorylation of GSK3B protein] CTD PMID:32653415 GSK3B Human pentetrazol decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Pentylenetetrazole results in decreased phosphorylation of GSK3B protein CTD PMID:32653415 GSK3B Human perfluorododecanoic acid decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 perfluorododecanoic acid results in decreased expression of GSK3B protein and perfluorododecanoic acid results in decreased expression of GSK3B protein modified form CTD PMID:23353032 GSK3B Human perfluorododecanoic acid affects response to substance ISO Gsk3b (Rattus norvegicus) 6480464 GSK3B protein affects the susceptibility to perfluorododecanoic acid CTD PMID:23353032 GSK3B Human perfluorononanoic acid increases expression ISO Gsk3b (Rattus norvegicus) 6480464 perfluoro-n-nonanoic acid results in increased expression of GSK3B protein modified form CTD PMID:22387981 GSK3B Human perfluorooctane-1-sulfonic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 Lithium Chloride inhibits the reaction [perfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein] CTD PMID:27018151 GSK3B Human perfluorooctane-1-sulfonic acid decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 perfluorooctane sulfonic acid results in decreased phosphorylation of GSK3B protein CTD PMID:27018151 GSK3B Human perfluorooctanoic acid increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 perfluorooctanoic acid results in increased phosphorylation of GSK3B protein CTD PMID:28947262 GSK3B Human phenethyl isothiocyanate multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased phosphorylation of GSK3B protein] CTD PMID:25246272 GSK3B Human phenethyl isothiocyanate increases phosphorylation EXP 6480464 phenethyl isothiocyanate results in increased phosphorylation of GSK3B protein CTD PMID:25246272 GSK3B Human phenobarbital decreases expression ISO Gsk3b (Mus musculus) 6480464 Phenobarbital results in decreased expression of GSK3B mRNA CTD PMID:23091169 GSK3B Human phenylephrine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 GRK2 protein affects the reaction [Phenylephrine results in increased phosphorylation of GSK3B protein] and SGK1 protein promotes the reaction [Phenylephrine results in increased phosphorylation of GSK3B protein] CTD PMID:15795328 and PMID:28759639 GSK3B Human phenylephrine increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Phenylephrine results in increased phosphorylation of GSK3B protein CTD PMID:15795328 and PMID:28759639 GSK3B Human phloretin decreases activity EXP 6480464 Phloretin results in decreased activity of GSK3B protein CTD PMID:16968061 GSK3B Human phloroglucinol decreases phosphorylation EXP 6480464 Phloroglucinol analog results in decreased phosphorylation of GSK3B protein CTD PMID:23178381 GSK3B Human phorbol 13-acetate 12-myristate increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein CTD PMID:17993264 GSK3B Human phorbol 13-acetate 12-myristate multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein] CTD PMID:17993264 GSK3B Human phytoestrogen increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Phytoestrogens results in increased phosphorylation of GSK3B protein CTD PMID:24726523 GSK3B Human phytoestrogen multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein] and fulvestrant inhibits the reaction [Phytoestrogens results in increased phosphorylation of GSK3B protein] CTD PMID:24726523 GSK3B Human pioglitazone increases expression EXP 6480464 Pioglitazone results in increased expression of GSK3B mRNA CTD PMID:32589349 GSK3B Human Plantamajoside multiple interactions ISO Gsk3b (Mus musculus) 6480464 plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:31009642 GSK3B Human Plantamajoside multiple interactions EXP 6480464 AKT1 protein modified form inhibits the reaction [Metformin promotes the reaction [plantamajoside results in decreased phosphorylation of GSK3B protein]] and Metformin promotes the reaction [plantamajoside results in decreased phosphorylation of GSK3B protein] CTD PMID:35350904 GSK3B Human Plantamajoside decreases phosphorylation EXP 6480464 plantamajoside results in decreased phosphorylation of GSK3B protein CTD PMID:35350904 GSK3B Human Plantamajoside multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 plantamajoside inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:31009642 GSK3B Human PNU-282987 multiple interactions EXP 6480464 [PNU-282987 binds to and results in increased activity of CHRNA7 protein] inhibits the reaction [Okadaic Acid results in increased expression of GSK3B protein modified form] more ... CTD PMID:21715663 GSK3B Human potassium atom multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 GW 506033X promotes the reaction [Potassium deficiency results in decreased phosphorylation of GSK3B protein] and Potassium results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:15950778 and PMID:19046382 GSK3B Human potassium atom decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Potassium deficiency results in decreased phosphorylation of GSK3B protein CTD PMID:19046382 GSK3B Human potassium chromate multiple interactions EXP 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of GSK3B mRNA CTD PMID:22079256 GSK3B Human potassium chromate decreases expression EXP 6480464 potassium chromate(VI) results in decreased expression of GSK3B mRNA CTD PMID:22079256 GSK3B Human proanthocyanidin multiple interactions EXP 6480464 Lithium Chloride inhibits the reaction [Proanthocyanidins results in decreased phosphorylation of GSK3B protein] CTD PMID:37551626 GSK3B Human proanthocyanidin decreases phosphorylation EXP 6480464 Proanthocyanidins results in decreased phosphorylation of GSK3B protein CTD PMID:37551626 GSK3B Human procyanidin B1 multiple interactions EXP 6480464 [p-coumaric acid co-treated with procyanidin B1] results in decreased expression of and results in decreased phosphorylation of GSK3B protein and procyanidin B1 results in decreased expression of and results in decreased phosphorylation of GSK3B protein CTD PMID:34342938 GSK3B Human procyanidin B2 multiple interactions EXP 6480464 procyanidin B2 inhibits the reaction [MFGE8 protein results in decreased expression of GSK3B protein modified form] CTD PMID:21505870 GSK3B Human procyanidin B2 increases expression EXP 6480464 procyanidin B2 results in increased expression of GSK3B protein modified form CTD PMID:21505870 GSK3B Human progesterone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Progesterone results in increased phosphorylation of GSK3B protein] CTD PMID:16882987 GSK3B Human progesterone decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Progesterone results in decreased expression of GSK3B mRNA and Progesterone results in decreased expression of GSK3B protein CTD PMID:17170212 and PMID:17443805 GSK3B Human progesterone decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Progesterone results in decreased phosphorylation of GSK3B protein CTD PMID:17443805 GSK3B Human progesterone multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Estradiol inhibits the reaction [Progesterone results in decreased expression of GSK3B mRNA] CTD PMID:17170212 GSK3B Human progesterone multiple interactions ISO Gsk3b (Mus musculus) 6480464 Progesterone inhibits the reaction [Estradiol results in increased phosphorylation of GSK3B protein] CTD PMID:15845746 GSK3B Human progesterone increases phosphorylation EXP 6480464 Progesterone results in increased phosphorylation of GSK3B protein CTD PMID:16882987 GSK3B Human propofol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Dexmedetomidine inhibits the reaction [Propofol results in decreased phosphorylation of and results in increased activity of GSK3B protein] and Propofol results in decreased phosphorylation of and results in increased activity of GSK3B protein CTD PMID:31187143 GSK3B Human propranolol decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Propranolol results in decreased phosphorylation of GSK3B protein CTD PMID:22982863 GSK3B Human prostaglandin E2 increases phosphorylation EXP 6480464 Dinoprostone results in increased phosphorylation of GSK3B protein CTD PMID:18395713 GSK3B Human prostaglandin E2 multiple interactions EXP 6480464 cryptotanshinone inhibits the reaction [Dinoprostone results in decreased expression of GSK3B protein] CTD PMID:30208247 GSK3B Human prostaglandin E2 decreases expression EXP 6480464 Dinoprostone results in decreased expression of GSK3B protein CTD PMID:30208247 GSK3B Human prostaglandin E2 increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Dinoprostone results in increased phosphorylation of GSK3B protein CTD PMID:20578217 GSK3B Human pterostilbene multiple interactions ISO Gsk3b (Mus musculus) 6480464 pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of GSK3B protein] CTD PMID:20681671 GSK3B Human puerarin multiple interactions ISO Gsk3b (Mus musculus) 6480464 [1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased phosphorylation of GSK3B protein CTD PMID:32763437 GSK3B Human puerarin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [1-Methyl-4-phenylpyridinium co-treated with puerarin] results in increased phosphorylation of GSK3B protein CTD PMID:32763437 GSK3B Human pyrithione multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein more ... CTD PMID:17098228 GSK3B Human pyrrolidine dithiocarbamate increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 pyrrolidine dithiocarbamic acid results in increased phosphorylation of GSK3B protein CTD PMID:17409235 GSK3B Human quercetin multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [Okadaic Acid affects the phosphorylation of GSK3B protein]] more ... CTD PMID:27050422 and PMID:27260466 GSK3B Human quercetin decreases phosphorylation EXP 6480464 Quercetin results in decreased phosphorylation of GSK3B protein CTD PMID:35688186 GSK3B Human quercetin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein] more ... CTD PMID:23117658 more ... GSK3B Human quercetin multiple interactions EXP 6480464 Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of GSK3B protein] CTD PMID:25380086 GSK3B Human quercetin decreases activity EXP 6480464 Quercetin results in decreased activity of GSK3B protein CTD PMID:16968061 GSK3B Human quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of GSK3B mRNA and Quercetin results in decreased expression of GSK3B protein CTD PMID:16968065 and PMID:23727915 GSK3B Human quinacrine increases expression EXP 6480464 Quinacrine results in increased expression of GSK3B mRNA CTD PMID:28720477 GSK3B Human quinacrine multiple interactions EXP 6480464 GSK3B protein affects the reaction [Quinacrine results in decreased expression of CCND1 protein] more ... CTD PMID:28720477 GSK3B Human radon atom decreases expression EXP 6480464 Radon results in decreased expression of GSK3B protein CTD PMID:32949624 GSK3B Human radon(0) decreases expression EXP 6480464 Radon results in decreased expression of GSK3B protein CTD PMID:32949624 GSK3B Human raffinose increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Raffinose results in increased phosphorylation of GSK3B protein CTD PMID:29458019 GSK3B Human raffinose increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Raffinose results in increased phosphorylation of GSK3B protein CTD PMID:29458019 GSK3B Human Rebamipide increases expression ISO Gsk3b (Rattus norvegicus) 6480464 rebamipide results in increased expression of GSK3B mRNA CTD PMID:18299717 GSK3B Human resveratrol affects phosphorylation ISO Gsk3b (Mus musculus) 6480464 resveratrol affects the phosphorylation of GSK3B protein CTD PMID:24254769 GSK3B Human resveratrol decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 resveratrol results in decreased phosphorylation of GSK3B protein CTD PMID:24675465 GSK3B Human resveratrol increases phosphorylation EXP 6480464 resveratrol results in increased phosphorylation of GSK3B protein CTD PMID:14750165 more ... GSK3B Human resveratrol decreases phosphorylation EXP 6480464 resveratrol results in decreased phosphorylation of GSK3B protein CTD PMID:14750165 more ... GSK3B Human resveratrol multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol results in increased phosphorylation of and results in decreased activity of GSK3B protein] more ... CTD PMID:20542495 more ... GSK3B Human resveratrol increases activity EXP 6480464 resveratrol results in increased activity of GSK3B protein CTD PMID:17868649 and PMID:20090934 GSK3B Human resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of GSK3B protein modified form CTD PMID:20133117 and PMID:20457218 GSK3B Human resveratrol affects expression EXP 6480464 resveratrol affects the expression of GSK3B protein modified form CTD PMID:22234583 GSK3B Human resveratrol decreases activity EXP 6480464 resveratrol results in decreased activity of GSK3B protein CTD PMID:19620254 GSK3B Human resveratrol multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of GSK3B protein] more ... CTD PMID:14750165 more ... GSK3B Human resveratrol increases expression EXP 6480464 resveratrol results in increased expression of GSK3B protein modified form CTD PMID:21505870 GSK3B Human resveratrol multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 1H-(1 more ... CTD PMID:16860989 more ... GSK3B Human resveratrol increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Resveratrol results in increased phosphorylation of GSK3B protein CTD PMID:22180358 and PMID:23129026 GSK3B Human riboflavin increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Riboflavin analog results in increased phosphorylation of GSK3B protein and Riboflavin results in increased phosphorylation of GSK3B protein CTD PMID:20688149 GSK3B Human risperidone multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 DRD2 protein affects the reaction [Risperidone results in increased expression of GSK3B protein] CTD PMID:16144542 GSK3B Human risperidone increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Risperidone results in increased expression of GSK3B protein CTD PMID:16144542 GSK3B Human Ro 31-8220 decreases activity EXP 6480464 Ro 31-8220 results in decreased activity of GSK3B protein CTD PMID:10998351 GSK3B Human rotenone affects expression ISO Gsk3b (Mus musculus) 6480464 Rotenone affects the expression of GSK3B mRNA CTD PMID:23186747 GSK3B Human rotenone decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Rotenone results in decreased phosphorylation of GSK3B protein CTD PMID:36048341 GSK3B Human rotenone multiple interactions ISO Gsk3b (Mus musculus) 6480464 Chlorogenic Acid inhibits the reaction [Rotenone results in decreased phosphorylation of GSK3B protein] more ... CTD PMID:36048341 and PMID:36774383 GSK3B Human rotenone increases expression EXP 6480464 Rotenone results in increased expression of GSK3B mRNA CTD PMID:33512557 GSK3B Human rotenone decreases phosphorylation EXP 6480464 Rotenone results in decreased phosphorylation of GSK3B protein CTD PMID:28245986 GSK3B Human rotenone multiple interactions EXP 6480464 1 more ... CTD PMID:28245986 GSK3B Human rotenone multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 1 more ... CTD PMID:25433145 and PMID:28245986 GSK3B Human rotenone decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Rotenone results in decreased phosphorylation of GSK3B protein CTD PMID:25433145 and PMID:28245986 GSK3B Human rottlerin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Cadmium co-treated with rottlerin] results in decreased expression of GSK3B protein and rottlerin inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein] CTD PMID:27658547 GSK3B Human rottlerin decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 rottlerin results in decreased expression of GSK3B protein CTD PMID:27658547 GSK3B Human royal jelly multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 royal jelly inhibits the reaction [Fluorides results in increased expression of GSK3B protein] CTD PMID:34227456 GSK3B Human rubimaillin increases phosphorylation EXP 6480464 rubimaillin results in increased phosphorylation of GSK3B protein CTD PMID:23466342 GSK3B Human ruthenium atom decreases activity EXP 6480464 Ruthenium results in decreased activity of GSK3B protein CTD PMID:17210701 GSK3B Human Salinomycin decreases expression EXP 6480464 salinomycin results in decreased expression of GSK3B mRNA CTD PMID:19682730 GSK3B Human Salvianolic acid A multiple interactions ISO Gsk3b (Mus musculus) 6480464 salvianolic acid A affects the reaction [[Streptozocin co-treated with [APOE protein affects the susceptibility to Dietary Fats]] affects the phosphorylation of GSK3B protein] CTD PMID:39047806 GSK3B Human SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [DEFA1 protein results in increased phosphorylation of GSK3B protein] and SB 203580 inhibits the reaction [DEFA2 protein results in increased phosphorylation of GSK3B protein] CTD PMID:19814765 GSK3B Human SB 203580 decreases activity EXP 6480464 SB 203580 results in decreased activity of GSK3B protein CTD PMID:10998351 GSK3B Human SB 415286 multiple interactions EXP 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:15753396 and PMID:31563592 GSK3B Human SB 415286 multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 and 5-dione inhibits the reaction [Sevoflurane results in decreased phosphorylation of GSK3B protein] CTD PMID:33548343 GSK3B Human SB 415286 multiple interactions ISO Gsk3b (Mus musculus) 6480464 [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 and 5-dione results in decreased activity of GSK3B protein] which results in increased expression of CTNNB1 protein CTD PMID:19159680 GSK3B Human SB 415286 decreases activity ISO Gsk3b (Mus musculus) 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 and 5-dione results in decreased activity of GSK3B protein CTD PMID:19159680 GSK3B Human SB 431542 multiple interactions EXP 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:37664457 GSK3B Human SB-239063 multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased susceptibility to SB 239063] which results in increased phosphorylation of GSK3B protein CTD PMID:26116440 GSK3B Human sclareol decreases phosphorylation EXP 6480464 sclareol results in decreased phosphorylation of GSK3B protein CTD PMID:33164868 GSK3B Human selenium atom multiple interactions EXP 6480464 [Selenium co-treated with Vitamin E] results in increased expression of GSK3B mRNA and Selenium inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein] CTD PMID:17339365 and PMID:19244175 GSK3B Human selenium atom decreases phosphorylation EXP 6480464 Selenium results in decreased phosphorylation of GSK3B protein CTD PMID:17339365 GSK3B Human selenium atom decreases expression EXP 6480464 Selenium results in decreased expression of GSK3B mRNA CTD PMID:19244175 GSK3B Human serotonin increases phosphorylation EXP 6480464 Serotonin results in increased phosphorylation of GSK3B protein CTD PMID:20190034 GSK3B Human serpentine asbestos multiple interactions EXP 6480464 1 more ... CTD PMID:26685284 GSK3B Human serpentine asbestos increases phosphorylation EXP 6480464 Asbestos and Serpentine results in increased phosphorylation of GSK3B protein CTD PMID:26685284 and PMID:30609805 GSK3B Human sesquiterpene multiple interactions EXP 6480464 Sesquiterpenes analog results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:30672058 GSK3B Human sevoflurane decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Sevoflurane results in decreased phosphorylation of GSK3B protein CTD PMID:20807582 and PMID:33548343 GSK3B Human sevoflurane multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:20807582 and PMID:33548343 GSK3B Human silicon dioxide decreases phosphorylation EXP 6480464 Silicon Dioxide analog results in decreased phosphorylation of GSK3B protein CTD PMID:24831964 GSK3B Human silicon dioxide increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Silicon Dioxide results in increased phosphorylation of GSK3B protein CTD PMID:36223831 GSK3B Human silicon dioxide increases phosphorylation EXP 6480464 Silicon Dioxide results in increased phosphorylation of GSK3B protein CTD PMID:36223831 GSK3B Human silicon dioxide decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Silicon Dioxide analog results in decreased phosphorylation of GSK3B protein CTD PMID:24831964 GSK3B Human silver atom affects phosphorylation EXP 6480464 Silver affects the phosphorylation of GSK3B protein CTD PMID:27593553 GSK3B Human silver(0) affects phosphorylation EXP 6480464 Silver affects the phosphorylation of GSK3B protein CTD PMID:27593553 GSK3B Human simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of GSK3B CTD PMID:19461118 GSK3B Human simvastatin increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Simvastatin results in increased expression of GSK3B protein modified form CTD PMID:18004065 GSK3B Human simvastatin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Simvastatin inhibits the reaction [Glucose results in decreased phosphorylation of and results in increased activity of GSK3B protein] and Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of GSK3B protein] CTD PMID:18004065 and PMID:18047562 GSK3B Human sirolimus multiple interactions EXP 6480464 [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2 more ... CTD PMID:15753396 and PMID:17908691 GSK3B Human sirolimus multiple interactions ISO Gsk3b (Mus musculus) 6480464 Sirolimus inhibits the reaction [TSC1 gene mutant form results in decreased phosphorylation of GSK3B protein] CTD PMID:18495876 GSK3B Human sirolimus increases activity EXP 6480464 Sirolimus results in increased activity of GSK3B protein CTD PMID:15753396 GSK3B Human sodium arsenate decreases expression ISO Gsk3b (Mus musculus) 6480464 sodium arsenate results in decreased expression of GSK3B mRNA CTD PMID:21795629 GSK3B Human sodium arsenate increases expression ISO Gsk3b (Mus musculus) 6480464 sodium arsenate results in increased expression of GSK3B mRNA CTD PMID:21795629 GSK3B Human sodium arsenite multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased phosphorylation of GSK3B protein] more ... CTD PMID:12614848 more ... GSK3B Human sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of GSK3B protein CTD PMID:29107899 and PMID:30528433 GSK3B Human sodium arsenite multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of GSK3B protein]] more ... CTD PMID:27966075 more ... GSK3B Human sodium arsenite decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 sodium arsenite results in decreased phosphorylation of GSK3B protein CTD PMID:27966075 more ... GSK3B Human sodium arsenite increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 sodium arsenite results in increased phosphorylation of GSK3B protein CTD PMID:12529330 GSK3B Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of GSK3B mRNA and sodium arsenite results in increased expression of GSK3B protein modified form CTD PMID:16054901 and PMID:38568856 GSK3B Human sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of GSK3B protein CTD PMID:17849503 more ... GSK3B Human sodium arsenite decreases phosphorylation EXP 6480464 sodium arsenite results in decreased phosphorylation of GSK3B protein CTD PMID:20043101 and PMID:33256086 GSK3B Human sodium dichromate decreases expression ISO Gsk3b (Mus musculus) 6480464 sodium bichromate results in decreased expression of GSK3B mRNA CTD PMID:22155349 GSK3B Human sodium dichromate multiple interactions EXP 6480464 [sodium bichromate co-treated with isorhapontigenin] results in increased phosphorylation of GSK3B protein CTD PMID:37619952 GSK3B Human sodium fluoride multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 DKK1 protein inhibits the reaction [Sodium Fluoride results in increased phosphorylation of GSK3B protein] CTD PMID:24300170 GSK3B Human sodium fluoride increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Sodium Fluoride results in increased phosphorylation of GSK3B protein CTD PMID:24300170 GSK3B Human sorafenib multiple interactions EXP 6480464 arsenic trioxide inhibits the reaction [sorafenib results in increased phosphorylation of GSK3B protein] more ... CTD PMID:17991738 and PMID:25416439 GSK3B Human sorafenib increases phosphorylation EXP 6480464 sorafenib results in increased phosphorylation of GSK3B protein CTD PMID:25416439 GSK3B Human sphingosine 1-phosphate multiple interactions EXP 6480464 sphingosine 1-phosphate affects the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein] and Wortmannin affects the reaction [sphingosine 1-phosphate affects the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein]] CTD PMID:25769802 GSK3B Human streptozocin increases expression ISO Gsk3b (Rattus norvegicus) 6480464 Streptozocin results in increased expression of GSK3B mRNA CTD PMID:27038876 GSK3B Human streptozocin decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Streptozocin results in decreased phosphorylation of GSK3B protein CTD PMID:28422052 more ... GSK3B Human streptozocin multiple interactions ISO Gsk3b (Mus musculus) 6480464 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] more ... CTD PMID:33484791 more ... GSK3B Human streptozocin decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Streptozocin results in decreased phosphorylation of GSK3B protein CTD PMID:25541178 more ... GSK3B Human streptozocin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein more ... CTD PMID:25541178 more ... GSK3B Human succimer multiple interactions ISO Gsk3b (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of GSK3B mRNA and [Succimer co-treated with Magnetite Nanoparticles] affects the expression of GSK3B mRNA CTD PMID:21641980 and PMID:26378955 GSK3B Human sulfasalazine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of GSK3B protein] CTD PMID:26165751 GSK3B Human sulforaphane multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased phosphorylation of and results in decreased activity of GSK3B protein] and sulforaphane results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:29353218 GSK3B Human sulforaphane multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased phosphorylation of and results in decreased activity of GSK3B protein] and sulforaphane results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:29353218 GSK3B Human sulindac decreases phosphorylation EXP 6480464 Sulindac results in decreased phosphorylation of GSK3B protein CTD PMID:11593435 GSK3B Human syringic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 syringic acid inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of and results in decreased phosphorylation of GSK3B protein] CTD PMID:31586550 GSK3B Human T-2 toxin decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 T-2 Toxin results in decreased expression of GSK3B mRNA CTD PMID:26141394 GSK3B Human T-2 toxin increases expression ISO Gsk3b (Mus musculus) 6480464 T-2 Toxin results in increased expression of GSK3B protein CTD PMID:35289972 and PMID:36402210 GSK3B Human T-2 toxin multiple interactions ISO Gsk3b (Mus musculus) 6480464 3-methyladenine promotes the reaction [T-2 Toxin results in increased expression of GSK3B protein] CTD PMID:36402210 GSK3B Human tacrolimus hydrate multiple interactions EXP 6480464 [GSK3A protein co-treated with GSK3B protein] affects the reaction [Tacrolimus results in increased expression of SNAI1 protein] CTD PMID:22416070 GSK3B Human tacrolimus hydrate increases phosphorylation EXP 6480464 Tacrolimus results in increased phosphorylation of GSK3B protein CTD PMID:22416070 GSK3B Human tadalafil multiple interactions ISO Gsk3b (Mus musculus) 6480464 Tadalafil inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] and Tadalafil inhibits the reaction [Thioacetamide results in decreased phosphorylation of GSK3B protein] CTD PMID:31323263 and PMID:34428446 GSK3B Human tamibarotene affects expression EXP 6480464 tamibarotene affects the expression of GSK3B mRNA CTD PMID:15498508 GSK3B Human tamoxifen multiple interactions EXP 6480464 Tamoxifen promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] and Tamoxifen results in decreased phosphorylation of and results in increased expression of GSK3B protein CTD PMID:22046442 and PMID:23921149 GSK3B Human tamoxifen affects phosphorylation EXP 6480464 Tamoxifen affects the phosphorylation of GSK3B protein CTD PMID:34463000 GSK3B Human tanespimycin decreases expression EXP 6480464 tanespimycin results in decreased expression of GSK3B protein modified form CTD PMID:20090934 GSK3B Human Tanshinone I decreases expression ISO Gsk3b (Mus musculus) 6480464 tanshinone results in decreased expression of GSK3B mRNA CTD PMID:25186638 GSK3B Human taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] CTD PMID:30362509 GSK3B Human taurine multiple interactions ISO Gsk3b (Mus musculus) 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein] CTD PMID:30362509 GSK3B Human taurochenodeoxycholic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 Taurochenodeoxycholic Acid results in increased phosphorylation of and results in decreased activity of GSK3B protein CTD PMID:20512997 GSK3B Human temozolomide multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Temozolomide results in increased phosphorylation of GSK3B protein] CTD PMID:31758290 GSK3B Human temozolomide increases phosphorylation EXP 6480464 Temozolomide results in increased phosphorylation of GSK3B protein CTD PMID:31758290 GSK3B Human temozolomide increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Temozolomide results in increased phosphorylation of GSK3B protein CTD PMID:31758290 GSK3B Human temozolomide multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Temozolomide results in increased phosphorylation of GSK3B protein] CTD PMID:31758290 GSK3B Human tert-butyl hydroperoxide decreases phosphorylation EXP 6480464 tert-Butylhydroperoxide results in decreased phosphorylation of GSK3B protein CTD PMID:29128606 GSK3B Human tert-butyl hydroperoxide multiple interactions EXP 6480464 3 and 4-dihydroxyphenyllactic acid inhibits the reaction [tert-Butylhydroperoxide results in decreased phosphorylation of GSK3B protein] CTD PMID:29128606 GSK3B Human tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of GSK3B mRNA CTD PMID:15336504 GSK3B Human testosterone increases expression EXP 6480464 Testosterone results in increased expression of GSK3B mRNA CTD PMID:21880219 GSK3B Human testosterone multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein and Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein] CTD PMID:25164625 GSK3B Human testosterone enanthate affects expression EXP 6480464 testosterone enanthate affects the expression of GSK3B mRNA CTD PMID:17440010 GSK3B Human tetrachloromethane multiple interactions ISO Gsk3b (Mus musculus) 6480464 Carbon Tetrachloride inhibits the reaction [Nicotine results in decreased expression of GSK3B mRNA] more ... CTD PMID:33640489 and PMID:35411647 GSK3B Human tetrachloromethane increases expression ISO Gsk3b (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of GSK3B mRNA CTD PMID:35411647 GSK3B Human tetrachloromethane decreases expression ISO Gsk3b (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of GSK3B mRNA and Carbon Tetrachloride results in decreased expression of GSK3B protein CTD PMID:33640489 and PMID:35411647 GSK3B Human tetrahydropalmatine decreases expression ISO Gsk3b (Mus musculus) 6480464 tetrahydropalmatine results in decreased expression of GSK3B mRNA CTD PMID:37606869 GSK3B Human theophylline increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Theophylline results in increased phosphorylation of GSK3B protein CTD PMID:32001318 GSK3B Human thioacetamide multiple interactions ISO Gsk3b (Mus musculus) 6480464 Tadalafil inhibits the reaction [Thioacetamide results in decreased phosphorylation of GSK3B protein] CTD PMID:31323263 GSK3B Human thioacetamide decreases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Thioacetamide results in decreased phosphorylation of GSK3B protein CTD PMID:31323263 GSK3B Human thiram increases expression EXP 6480464 Thiram results in increased expression of GSK3B mRNA CTD PMID:38568856 GSK3B Human thymoquinone multiple interactions EXP 6480464 Lithium Chloride inhibits the reaction [thymoquinone results in decreased phosphorylation of GSK3B protein] and XAV939 promotes the reaction [thymoquinone results in decreased phosphorylation of GSK3B protein] CTD PMID:32112862 GSK3B Human thymoquinone multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 thymoquinone inhibits the reaction [bisphenol A results in decreased phosphorylation of GSK3B protein] CTD PMID:33315269 GSK3B Human thymoquinone decreases phosphorylation EXP 6480464 thymoquinone results in decreased phosphorylation of GSK3B protein CTD PMID:32112862 GSK3B Human tideglusib increases expression EXP 6480464 tideglusib results in increased expression of GSK3B protein modified form CTD PMID:30965670 GSK3B Human tideglusib decreases activity EXP 6480464 tideglusib results in decreased activity of GSK3B protein CTD PMID:30965670 GSK3B Human titanium dioxide decreases methylation ISO Gsk3b (Mus musculus) 6480464 titanium dioxide results in decreased methylation of GSK3B gene CTD PMID:35295148 GSK3B Human tolonium chloride increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Tolonium Chloride results in increased phosphorylation of GSK3B protein CTD PMID:36027949 GSK3B Human tolonium chloride decreases expression ISO Gsk3b (Mus musculus) 6480464 Tolonium Chloride results in decreased expression of GSK3B protein CTD PMID:36027949 GSK3B Human toluene 2,4-diisocyanate multiple interactions ISO Gsk3b (Mus musculus) 6480464 2-(1 more ... CTD PMID:26089345 and PMID:30517707 GSK3B Human toluene 2,4-diisocyanate increases phosphorylation ISO Gsk3b (Mus musculus) 6480464 Toluene 2 and 4-Diisocyanate results in increased phosphorylation of GSK3B protein CTD PMID:26089345 and PMID:30517707 GSK3B Human topiramate multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 topiramate inhibits the reaction [3-nitropropionic acid results in decreased phosphorylation of GSK3B protein] CTD PMID:29753867 GSK3B Human topotecan multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of GSK3B mRNA CTD PMID:25729387 GSK3B Human trametinib multiple interactions ISO Gsk3b (Mus musculus) 6480464 [trametinib co-treated with 6-bromoindirubin-3'-oxime] affects the phosphorylation of GSK3B protein CTD PMID:37116855 GSK3B Human trichloroethene multiple interactions EXP 6480464 11-(2-pyrrolidin-1-ylethoxy)-14 more ... CTD PMID:34233590 GSK3B Human trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of GSK3B protein CTD PMID:34233590 GSK3B Human Triptolide increases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 triptolide results in increased phosphorylation of GSK3B protein CTD PMID:30926361 GSK3B Human Triptolide multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Lithium Chloride inhibits the reaction [triptolide results in increased phosphorylation of GSK3B protein] CTD PMID:30926361 GSK3B Human troglitazone multiple interactions EXP 6480464 [N-(4-methoxybenzyl)-N'-(5-nitro-1 more ... CTD PMID:20540935 GSK3B Human troglitazone decreases activity EXP 6480464 troglitazone results in decreased activity of GSK3B protein CTD PMID:20540935 GSK3B Human troglitazone affects response to substance EXP 6480464 GSK3B protein affects the susceptibility to troglitazone CTD PMID:20540935 GSK3B Human tungsten decreases expression ISO Gsk3b (Mus musculus) 6480464 Tungsten results in decreased expression of GSK3B mRNA CTD PMID:30912803 GSK3B Human urethane increases expression EXP 6480464 Urethane results in increased expression of GSK3B mRNA CTD PMID:28818685 GSK3B Human Ursonic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 ursonic acid promotes the reaction [INS1 protein results in decreased phosphorylation of GSK3B protein] CTD PMID:36933777 GSK3B Human valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:19328817 and PMID:27188386 GSK3B Human valproic acid increases expression ISO Gsk3b (Mus musculus) 6480464 Valproic Acid results in increased expression of GSK3B mRNA CTD PMID:31445079 GSK3B Human valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of GSK3B mRNA CTD PMID:26272509 GSK3B Human valproic acid multiple interactions ISO Gsk3b (Mus musculus) 6480464 4-benzyl-2-methyl-1 more ... CTD PMID:25453207 GSK3B Human valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of GSK3B mRNA CTD PMID:25979313 GSK3B Human valproic acid decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 Valproic Acid results in decreased expression of GSK3B mRNA CTD PMID:19359144 GSK3B Human valproic acid increases phosphorylation EXP 6480464 Valproic Acid results in increased phosphorylation of GSK3B protein CTD PMID:19440698 GSK3B Human valproic acid decreases activity EXP 6480464 Valproic Acid results in decreased activity of GSK3B protein CTD PMID:19101580 GSK3B Human valsartan multiple interactions ISO Gsk3b (Mus musculus) 6480464 Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:31009642 GSK3B Human valsartan multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Valsartan inhibits the reaction [Isoproterenol results in increased phosphorylation of GSK3B protein] CTD PMID:31009642 GSK3B Human vanillic acid multiple interactions EXP 6480464 Vanillic Acid inhibits the reaction [INS protein results in increased expression of GSK3B protein] CTD PMID:33651899 GSK3B Human vinclozolin affects expression ISO Gsk3b (Rattus norvegicus) 6480464 vinclozolin affects the expression of GSK3B mRNA CTD PMID:19015723 GSK3B Human vitamin E multiple interactions EXP 6480464 [Selenium co-treated with Vitamin E] results in increased expression of GSK3B mRNA CTD PMID:19244175 GSK3B Human vitamin E decreases expression EXP 6480464 Vitamin E results in decreased expression of GSK3B mRNA CTD PMID:19244175 GSK3B Human vitamin E multiple interactions ISO Gsk3b (Mus musculus) 6480464 Vitamin E inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form] CTD PMID:15842767 GSK3B Human vitamin K multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein and Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein] CTD PMID:23117658 GSK3B Human warfarin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein and Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased phosphorylation of GSK3B protein] CTD PMID:23117658 GSK3B Human wogonin decreases expression EXP 6480464 wogonin results in decreased expression of GSK3B protein modified form CTD PMID:23872260 GSK3B Human wogonin increases expression ISO Gsk3b (Rattus norvegicus) 6480464 wogonin results in increased expression of GSK3B protein CTD PMID:23872260 GSK3B Human wogonin decreases expression ISO Gsk3b (Rattus norvegicus) 6480464 wogonin results in decreased expression of GSK3B protein modified form CTD PMID:23872260 GSK3B Human wortmannin multiple interactions EXP 6480464 Wortmannin affects the reaction [sphingosine 1-phosphate affects the reaction [beta-N-methylamino-L-alanine results in increased expression of GSK3B protein]] more ... CTD PMID:12614848 more ... GSK3B Human wortmannin decreases phosphorylation EXP 6480464 wortmannin results in decreased phosphorylation of GSK3B protein CTD PMID:20090934 and PMID:23178381 GSK3B Human wortmannin multiple interactions ISO Gsk3b (Mus musculus) 6480464 Melatonin inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form] more ... CTD PMID:15842767 and PMID:23170834 GSK3B Human wortmannin decreases expression ISO Gsk3b (Mus musculus) 6480464 wortmannin results in decreased expression of GSK3B protein modified form CTD PMID:15842767 GSK3B Human wortmannin multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 wortmannin inhibits the reaction [chaetoglobosins results in increased phosphorylation of GSK3B protein] more ... CTD PMID:18040759 more ... GSK3B Human xanthosine multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 xanthosine inhibits the reaction [Palmitates results in decreased phosphorylation of GSK3B protein] CTD PMID:36627075 GSK3B Human XAV939 multiple interactions EXP 6480464 XAV939 promotes the reaction [thymoquinone results in decreased phosphorylation of GSK3B protein] CTD PMID:32112862 GSK3B Human XAV939 decreases phosphorylation EXP 6480464 XAV939 results in decreased phosphorylation of GSK3B protein CTD PMID:32112862 GSK3B Human zinc atom multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein more ... CTD PMID:17098228 GSK3B Human zinc atom decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Zinc deficiency results in decreased phosphorylation of GSK3B protein CTD PMID:21893222 GSK3B Human zinc atom increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of GSK3B protein CTD PMID:17513037 GSK3B Human zinc atom multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein] and Wortmannin inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein] CTD PMID:17513037 GSK3B Human zinc sulfate multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 Melatonin promotes the reaction [Zinc Sulfate inhibits the reaction [Aluminum Chloride results in increased expression of GSK3B protein modified form]] more ... CTD PMID:35526705 GSK3B Human zinc(0) multiple interactions ISO Gsk3b (Rattus norvegicus) 6480464 [Zinc co-treated with pyrithione] results in increased phosphorylation of and results in increased activity of GSK3B protein more ... CTD PMID:17098228 GSK3B Human zinc(0) multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein] and Wortmannin inhibits the reaction [Zinc results in increased phosphorylation of GSK3B protein] CTD PMID:17513037 GSK3B Human zinc(0) increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of GSK3B protein CTD PMID:17513037 GSK3B Human zinc(0) decreases phosphorylation ISO Gsk3b (Rattus norvegicus) 6480464 Zinc deficiency results in decreased phosphorylation of GSK3B protein CTD PMID:21893222
