GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GSK3B | decreases phosphorylation | EXP | | 6480464 | CTD | celastrol results in decreased phosphorylation of GSK3B protein | PMID:31715269 | GSK3B | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [celastrol results in decreased phosphorylation of GSK3B protein]; GSK3B protein affects the reaction [celastrol results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [celastrol results in decreased phosphorylation of GSK3B protein] | PMID:31715269 | GSK3B | multiple interactions | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | celastrol affects the reaction [APC protein mutant form affects the phosphorylation of GSK3B protein] | PMID:31715269 | |
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