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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733891
Species: Homo sapiens
RGD Object: Gene
Symbol: GSK3B
Name: glycogen synthase kinase 3 beta
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSK3Bdecreases expressionEXP 6480464CTDmethylmercuric chloride results in decreased expression of GSK3B mRNAPMID:28001369
GSK3Bincreases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of GSK3B mRNAPMID:28001369
GSK3Bdecreases phosphorylationISOGsk3b (Rattus norvegicus)6480464CTDmethylmercuric chloride results in decreased phosphorylation of GSK3B proteinPMID:29258870
GSK3Bincreases expressionISOGsk3b (Mus musculus)6480464CTDmethylmercuric chloride results in increased expression of GSK3B mRNAPMID:20061341
GSK3Bincreases phosphorylationISOGsk3b (Rattus norvegicus)6480464CTDmethylmercuric chloride results in increased phosphorylation of GSK3B proteinPMID:28736149
GSK3Bmultiple interactionsISOGsk3b (Rattus norvegicus)6480464CTDmethylmercuric chloride results in decreased phosphorylation of and results in increased activity of GSK3B proteinPMID:28821999
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