GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GSK3B | affects response to substance | EXP | | 6480464 | CTD | GSK3B protein affects the susceptibility to cinobufagin | PMID:23164673 | GSK3B | increases expression | EXP | | 6480464 | CTD | cinobufagin results in increased expression of GSK3B protein modified form | PMID:23164673 | GSK3B | multiple interactions | EXP | | 6480464 | CTD | GSK3B protein mutant form inhibits the reaction [cinobufagin results in decreased expression of RELA protein]; GSK3B protein mutant form inhibits the reaction [cinobufagin results in increased expression of PARP1 protein modified form]; SB 216763 inhibits the reaction [cinobufagin results in increased expression of GSK3B protein modified form] | PMID:23164673 | | ||||||||||||||||||||||
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