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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733891
Species: Homo sapiens
RGD Object: Gene
Symbol: GSK3B
Name: glycogen synthase kinase 3 beta
Acc ID: CHEBI:44915
Term: propofol
Definition: A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Chemical ID: MESH:D015742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSK3Bmultiple interactionsISOGsk3b (Rattus norvegicus)6480464CTDDexmedetomidine inhibits the reaction [Propofol results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Propofol results in decreased phosphorylation of and results in increased activity of GSK3B proteinPMID:31187143
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