GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | GSK3B | decreases expression | EXP | | 6480464 | CTD | sodium arsenite results in decreased expression of GSK3B protein | PMID:29107899 PMID:30528433 | GSK3B | decreases phosphorylation | EXP | | 6480464 | CTD | sodium arsenite results in decreased phosphorylation of GSK3B protein | PMID:20043101 PMID:33256086 | GSK3B | increases expression | EXP | | 6480464 | CTD | sodium arsenite results in increased expression of GSK3B protein modified form | PMID:16054901 | GSK3B | increases phosphorylation | EXP | | 6480464 | CTD | sodium arsenite results in increased phosphorylation of GSK3B protein | PMID:17849503 PMID:22859221 PMID:26220687 | GSK3B | multiple interactions | EXP | | 6480464 | CTD | [Ethanol co-treated with sodium arsenite] results in increased phosphorylation of GSK3B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with INS protein co-treated with sodium arsenite] results in decreased phosphorylation of GSK3B protein; GSDMD protein affects the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with INS protein co-treated with sodium arsenite] results in decreased phosphorylation of GSK3B protein]; Lithium promotes the reaction [sodium arsenite results in increased phosphorylation of GSK3B protein]; sodium arsenite inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; sodium arsenite promotes the reaction [IRS1 protein binds to GSK3B protein]; sodium arsenite results in increased phosphorylation of and results in increased activity of GSK3B protein; Wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of GSK3B protein] | PMID:12614848 PMID:17849503 PMID:26220687 PMID:29526746 PMID:34920032 | GSK3B | decreases phosphorylation | ISO | Gsk3b (Rattus norvegicus) | 6480464 | CTD | sodium arsenite results in decreased phosphorylation of GSK3B protein | PMID:27966075 PMID:29723552 PMID:34920032 | GSK3B | increases phosphorylation | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | sodium arsenite results in increased phosphorylation of GSK3B protein | PMID:12529330 | GSK3B | multiple interactions | ISO | Gsk3b (Rattus norvegicus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of GSK3B protein]]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of GSK3B protein]; [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of GSK3B protein; Curcumin inhibits the reaction [sodium arsenite results in decreased phosphorylation of GSK3B protein]; IL1RN protein inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of GSK3B protein] | PMID:27966075 PMID:29723552 PMID:35993674 | | ||||||||||||||||||||||
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