MIR155 (microRNA 155) - Rat Genome Database

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Gene: MIR155 (microRNA 155) Homo sapiens
Analyze
Symbol: MIR155
Name: microRNA 155
RGD ID: 2299183
HGNC Page HGNC
Description: Predicted to act upstream of or within several processes, including cellular response to cytokine stimulus; cellular response to lipid; and regulation of gene expression. Implicated in colon adenocarcinoma; hepatocellular carcinoma; oropharynx cancer; and type 1 diabetes mellitus. Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and pancreatic carcinoma (multiple).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-155; MIRN155; miRNA155
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2125,573,980 - 25,574,044 (+)EnsemblGRCh38hg38GRCh38
GRCh382125,573,980 - 25,574,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372126,946,292 - 26,946,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera2112,129,700 - 12,129,764 (+)NCBI
Cytogenetic Map21q21.3NCBI
HuRef2112,349,435 - 12,349,499 (+)NCBIHuRef
CHM1_12126,506,960 - 26,507,024 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (ISO)
Acute Lung Injury  (ISO)
acute myeloid leukemia  (IEP)
acute myocardial infarction  (IEP)
acute pancreatitis  (IEP)
adult respiratory distress syndrome  (IEP)
Albuminuria  (EXP)
Alcoholic Fatty Liver  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (IAGP)
Angina Pectoris  (IEP)
Arsenic Poisoning  (IEP)
atherosclerosis  (IEP,ISO)
atrophic gastritis  (ISO)
autoimmune hepatitis  (IEP,ISO)
Behcet's disease  (IEP)
biliary atresia  (IEP)
Brain Injuries, Traumatic  (ISO)
Carcinoid Tumor  (EXP)
Chemical and Drug Induced Liver Injury  (ISO)
cholangiocarcinoma  (IEP)
cholera  (IEP)
Chronic Hepatitis B  (IEP)
Chronic Hepatitis C  (IEP)
chronic lymphocytic leukemia  (IEP)
Chronic Periodontitis  (IEP)
colon adenocarcinoma  (IMP)
colon cancer  (IEP,ISO)
Colonic Polyps  (ISO)
colorectal cancer  (IEP)
coronary artery disease  (IEP)
Crohn's disease  (IEP)
cystic fibrosis  (IEP)
Down syndrome  (EXP)
encephalomyelitis  (ISO)
Endotoxemia  (ISO)
Endotoxin Hyporesponsiveness  (ISO)
esophageal cancer  (IEP)
Experimental Colitis  (ISO)
familial adenomatous polyposis  (IEP)
Fibrosis  (ISO)
Flaviviridae Infections  (IEP)
gallbladder carcinoma  (IEP)
gastritis  (IEP)
head and neck squamous cell carcinoma  (IEP)
Helicobacter Infections  (IEP,ISO)
hepatitis B  (IEP)
hepatocellular carcinoma  (IAGP,IEP,IMP)
hyperglycemia  (ISO)
Insulin Resistance  (IEP,ISO)
Intervertebral Disc Disease  (IEP,ISO)
Intestinal Reperfusion Injury  (ISO)
liposarcoma  (IEP)
liver cirrhosis  (IEP)
Liver Injury  (ISO)
Liver Metastasis  (IEP)
Liver Reperfusion Injury  (ISO)
Lung Neoplasms  (EXP)
Lymphatic Metastasis  (IEP)
lymphoma  (ISS)
Mammary Neoplasms, Experimental  (IDA,IMP)
Microsatellite Instability  (EXP)
multiple myeloma  (IEP)
myocardial infarction  (ISO)
Neoplasm Invasiveness  (EXP)
Neoplasm Metastasis  (EXP,IEP)
Neoplastic Cell Transformation  (EXP)
Neurodevelopmental Disorders  (IAGP)
non-alcoholic fatty liver disease  (IEP,ISO)
obesity  (IEP,ISO)
Oral Lichen Planus  (IEP)
oral squamous cell carcinoma  (IEP)
oropharynx cancer  (IDA)
pancreatic carcinoma  (IEP)
pancreatic ductal adenocarcinoma  (IEP)
pancreatitis  (EXP)
Parkinson's disease  (ISO)
Pediatric Crohn's Disease  (IEP)
peritonitis  (ISO)
primary sclerosing cholangitis  (IEP)
prostate cancer  (IEP)
salivary gland adenoid cystic carcinoma  (IEP)
Sepsis  (IEP,ISO)
Septic Peritonitis  (IEP)
stomach cancer  (IEP)
tongue cancer  (IEP)
toxic shock syndrome  (IEP)
type 1 diabetes mellitus  (IAGP)
type 2 diabetes mellitus  (IEP)
ulcerative colitis  (IEP)
visceral leishmaniasis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
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Additional References at PubMed
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PMID:24362029   PMID:24376632   PMID:24387321   PMID:24391808   PMID:24403198   PMID:24403554   PMID:24447044   PMID:24460255   PMID:24494749   PMID:24519663   PMID:24522920   PMID:24525789  
PMID:24551280   PMID:24554510   PMID:24562503   PMID:24571026   PMID:24583476   PMID:24591085   PMID:24604078   PMID:24616504   PMID:24623016   PMID:24657879   PMID:24692283   PMID:24708856  
PMID:24743332   PMID:24789113   PMID:24793496   PMID:24804980   PMID:24805774   PMID:24806148   PMID:24824925   PMID:24840899   PMID:24854560   PMID:24856900   PMID:24876105   PMID:24877885  
PMID:24885259   PMID:24888652   PMID:24905663   PMID:24909288   PMID:24910152   PMID:24914134   PMID:24930753   PMID:24960647   PMID:24963214   PMID:24969405   PMID:25092123   PMID:25092144  
PMID:25128227   PMID:25142507   PMID:25143000   PMID:25155037   PMID:25157366   PMID:25175984   PMID:25180620   PMID:25182190   PMID:25185784   PMID:25197634   PMID:25211095   PMID:25219837  
PMID:25253569   PMID:25261908   PMID:25265435   PMID:25283550   PMID:25295729   PMID:25315114   PMID:25339368   PMID:25355421   PMID:25401928   PMID:25413124   PMID:25420938   PMID:25456009  
PMID:25480585   PMID:25484137   PMID:25486872   PMID:25503185   PMID:25522282   PMID:25528214   PMID:25535908   PMID:25601564   PMID:25614225   PMID:25630602   PMID:25633840   PMID:25666090  
PMID:25672593   PMID:25672607   PMID:25720442   PMID:25730818   PMID:25740880   PMID:25753878   PMID:25760478   PMID:25761610   PMID:25772938   PMID:25820993   PMID:25823817   PMID:25829072  
PMID:25850724   PMID:25853464   PMID:25869329   PMID:25872580   PMID:25873391   PMID:25888631   PMID:25910754   PMID:25916938   PMID:25918190   PMID:25929465   PMID:25953724   PMID:25965824  
PMID:25971362   PMID:25972604   PMID:25998827   PMID:26012521   PMID:26020803   PMID:26055806   PMID:26055960   PMID:26056431   PMID:26064968   PMID:26068396   PMID:26072128   PMID:26156524  
PMID:26159489   PMID:26176991   PMID:26188366   PMID:26191144   PMID:26195069   PMID:26211004   PMID:26223652   PMID:26261072   PMID:26261588   PMID:26307116   PMID:26317550   PMID:26324048  
PMID:26337206   PMID:26339601   PMID:26425555   PMID:26433115   PMID:26497687   PMID:26539029   PMID:26543233   PMID:26548866   PMID:26589288   PMID:26589478   PMID:26594049   PMID:26620207  
PMID:26621153   PMID:26624800   PMID:26646931   PMID:26657502   PMID:26752469   PMID:26779627   PMID:26780942   PMID:26795347   PMID:26823719   PMID:26829440   PMID:26831604   PMID:26841929  
PMID:26842862   PMID:26850462   PMID:26855180   PMID:26889816   PMID:26899994   PMID:26911687   PMID:26921773   PMID:26931072   PMID:26934326   PMID:26935979   PMID:26955820   PMID:26967247  
PMID:26986233   PMID:27009385   PMID:27014996   PMID:27016615   PMID:27028953   PMID:27041566   PMID:27064870   PMID:27065318   PMID:27079198   PMID:27086919   PMID:27110708   PMID:27113301  
PMID:27160903   PMID:27185878   PMID:27246008   PMID:27246706   PMID:27284727   PMID:27294145   PMID:27296000   PMID:27306418   PMID:27310932   PMID:27315591   PMID:27320691   PMID:27377409  
PMID:27411480   PMID:27412942   PMID:27420617   PMID:27462776   PMID:27470551   PMID:27473081   PMID:27497617   PMID:27530922   PMID:27534887   PMID:27535005   PMID:27565163   PMID:27601730  
PMID:27602769   PMID:27619068   PMID:27635110   PMID:27643599   PMID:27646435   PMID:27671860   PMID:27692344   PMID:27706699   PMID:27717891   PMID:27731397   PMID:27740637   PMID:27746237  
PMID:27751368   PMID:27761889   PMID:27783037   PMID:27786352   PMID:27796698   PMID:27811366   PMID:27872469   PMID:27880937   PMID:27885839   PMID:27903673   PMID:27981414   PMID:28006785  
PMID:28018919   PMID:28031239   PMID:28087411   PMID:28118944   PMID:28130497   PMID:28132399   PMID:28140712   PMID:28146070   PMID:28146427   PMID:28148469   PMID:28164567   PMID:28214207  
PMID:28240738   PMID:28247149   PMID:28251496   PMID:28259135   PMID:28281962   PMID:28301819   PMID:28316102   PMID:28371892   PMID:28402921   PMID:28407320   PMID:28407516   PMID:28408180  
PMID:28423578   PMID:28423722   PMID:28431233   PMID:28468592   PMID:28471953   PMID:28562349   PMID:28569050   PMID:28593612   PMID:28607031   PMID:28612526   PMID:28618412   PMID:28623945  
PMID:28627655   PMID:28628920   PMID:28642130   PMID:28647559   PMID:28662100   PMID:28664228   PMID:28664667   PMID:28683581   PMID:28685309   PMID:28688901   PMID:28700503   PMID:28720071  
PMID:28727276   PMID:28731457   PMID:28748483   PMID:28782994   PMID:28790455   PMID:28842954   PMID:28870579   PMID:28880456   PMID:28885613   PMID:28910312   PMID:28939896   PMID:28962081  
PMID:28967703   PMID:28994735   PMID:29017169   PMID:29066622   PMID:29103027   PMID:29115566   PMID:29146158   PMID:29191771   PMID:29240254   PMID:29247570   PMID:29249119   PMID:29281614  
PMID:29300789   PMID:29328396   PMID:29333944   PMID:29339071   PMID:29364476   PMID:29385860   PMID:29411649   PMID:29463948   PMID:29467762   PMID:29471005   PMID:29517281   PMID:29545091  
PMID:29550489   PMID:29582620   PMID:29601851   PMID:29620202   PMID:29627439   PMID:29654787   PMID:29658868   PMID:29661714   PMID:29693176   PMID:29751003   PMID:29752719   PMID:29767259  
PMID:29785488   PMID:29790117   PMID:29803178   PMID:29807272   PMID:29848325   PMID:29863307   PMID:29885519   PMID:29901087   PMID:29901097   PMID:29936517   PMID:29945912   PMID:29949145  
PMID:29981742   PMID:29991021   PMID:30006293   PMID:30015881   PMID:30031401   PMID:30032344   PMID:30046360   PMID:30049532   PMID:30091834   PMID:30125933   PMID:30171379   PMID:30201497  
PMID:30209639   PMID:30297336   PMID:30299211   PMID:30302809   PMID:30335891   PMID:30362157   PMID:30365045   PMID:30398001   PMID:30399324   PMID:30401711   PMID:30414370   PMID:30430204  
PMID:30458743   PMID:30465177   PMID:30468477   PMID:30478850   PMID:30482883   PMID:30485839   PMID:30515165   PMID:30536304   PMID:30554090   PMID:30621915   PMID:30670568   PMID:30692098  
PMID:30721153   PMID:30734973   PMID:30779069   PMID:30820789   PMID:30825229   PMID:30837408   PMID:30839051   PMID:30878390   PMID:30898623   PMID:30915770   PMID:30925928   PMID:30928987  
PMID:30950329   PMID:30962309   PMID:30968694   PMID:30998152   PMID:30998423   PMID:31009294   PMID:31016751   PMID:31036495   PMID:31081043   PMID:31090940   PMID:31162747   PMID:31173279  
PMID:31250987   PMID:31252530   PMID:31282135   PMID:31338876   PMID:31364113   PMID:31404910   PMID:31414764   PMID:31424663   PMID:31469179   PMID:31484730   PMID:31485611   PMID:31485649  
PMID:31487655   PMID:31502418   PMID:31505404   PMID:31531958   PMID:31570669   PMID:31599418   PMID:31601967   PMID:31603116   PMID:31628193   PMID:31657855   PMID:31669646   PMID:31696995  
PMID:31709859   PMID:31718618   PMID:31721599   PMID:31726271   PMID:31727002   PMID:31744065   PMID:31752013   PMID:31770330   PMID:31771044   PMID:31773704   PMID:31801218   PMID:31810510  
PMID:31819170   PMID:31849465   PMID:31851829   PMID:31852252   PMID:31856677   PMID:31872268   PMID:31880114   PMID:31907159   PMID:31907997   PMID:31909418   PMID:31910343   PMID:31918270  
PMID:31930529   PMID:31942966   PMID:31945413   PMID:31945658   PMID:31948758   PMID:31959117   PMID:32027250   PMID:32051698   PMID:32090104   PMID:32096299   PMID:32102529   PMID:32124227  
PMID:32151564   PMID:32196916   PMID:32215174   PMID:32220051   PMID:32227733   PMID:32237066   PMID:32243922   PMID:32248286   PMID:32289665   PMID:32323747   PMID:32323857   PMID:32331943  
PMID:32359033   PMID:32372074   PMID:32415722   PMID:32417393   PMID:32432745   PMID:32460356   PMID:32484820   PMID:32485219   PMID:32527448   PMID:32556361   PMID:32562373   PMID:32573268  
PMID:32580736   PMID:32587662   PMID:32602388   PMID:32614381   PMID:32634427   PMID:32666270   PMID:32696744   PMID:32702393   PMID:32707293   PMID:32720541   PMID:32770080   PMID:32798423  
PMID:32823863   PMID:32853020   PMID:32868076   PMID:32889908   PMID:32902755   PMID:32908449   PMID:32938348   PMID:32946865   PMID:32991030   PMID:33000196   PMID:33006449   PMID:33068176  
PMID:33081305   PMID:33090390   PMID:33121529   PMID:33125052   PMID:33134385   PMID:33174061   PMID:33179091   PMID:33221530   PMID:33268675   PMID:33283723   PMID:33287921   PMID:33317369  
PMID:33357126   PMID:33391256   PMID:33481955   PMID:33494773   PMID:33500248   PMID:33506901   PMID:33540559   PMID:33714739   PMID:33760254   PMID:33800594   PMID:33830643   PMID:33895969  
PMID:33919306   PMID:33957967   PMID:34022359   PMID:34024195   PMID:34105469   PMID:34171684  


Genomics

Comparative Map Data
MIR155
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2125,573,980 - 25,574,044 (+)EnsemblGRCh38hg38GRCh38
GRCh382125,573,980 - 25,574,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372126,946,292 - 26,946,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera2112,129,700 - 12,129,764 (+)NCBI
Cytogenetic Map21q21.3NCBI
HuRef2112,349,435 - 12,349,499 (+)NCBIHuRef
CHM1_12126,506,960 - 26,507,024 (+)NCBICHM1_1
Mir155
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391684,511,028 - 84,511,092 (+)NCBIGRCm39mm39
GRCm39 Ensembl1684,511,028 - 84,511,092 (+)Ensembl
GRCm381684,714,140 - 84,714,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1684,714,140 - 84,714,204 (+)EnsemblGRCm38mm10GRCm38
MGSCv371684,714,385 - 84,714,449 (+)NCBIGRCm37mm9NCBIm37
Celera1684,918,138 - 84,918,202 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
Mir155
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21123,774,654 - 23,774,718 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1123,774,654 - 23,774,718 (+)Ensembl
Rnor_6.01124,176,603 - 24,176,667 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,176,603 - 24,176,667 (+)EnsemblRnor6.0rn6Rnor6.0
Celera1123,614,233 - 23,614,297 (+)NCBICelera
Cytogenetic Map11q11NCBI
MIR155
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13121,078,768 - 21,078,828 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3121,078,758 - 21,078,833 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3121,138,038 - 21,138,098 (+)NCBI
ROS_Cfam_1.03121,132,843 - 21,132,903 (+)NCBI
UMICH_Zoey_3.13121,151,558 - 21,151,618 (+)NCBI
UNSW_CanFamBas_1.03121,152,631 - 21,152,691 (+)NCBI
UU_Cfam_GSD_1.03121,627,607 - 21,627,667 (+)NCBI
MIR155
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13189,138,822 - 189,138,902 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113189,138,822 - 189,138,902 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213199,063,344 - 199,063,424 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
TCF4hsa-miR-155-5pOncomiRDBexternal_infoNANA21460854
WEE1hsa-miR-155-5pOncomiRDBexternal_infoNANA20668041
FOXO3hsa-miR-155-5pOncomiRDBexternal_infoNANA20371610
SOCS1hsa-miR-155-5pOncomiRDBexternal_infoNANA20354188
MLH1hsa-miR-155-5pOncomiRDBexternal_infoNANA20351277
SMAD5hsa-miR-155-5pOncomiRDBexternal_infoNANA20133617
INPP5Dhsa-miR-155-5pOncomiRDBexternal_infoNANA19890474
CEBPBhsa-miR-155-5pOncomiRDBexternal_infoNANA19711427
AGTR1hsa-miR-155-5pOncomiRDBexternal_infoNANA19177201
TP53INP1hsa-miR-155-5pOncomiRDBexternal_infoNANA17911264
IRAK3hsa-miR-155-3pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI20852130
AGTR1hsa-miR-155-3pMirecordsexternal_info{unchanged}NA16675453
BACH1hsa-miR-155-3pMirecordsexternal_infoNANA17881434
AGTR1hsa-miR-155-3pMirecordsexternal_info{unchanged}{unchanged}NA17588946
AGTR1hsa-miR-155-3pMirecordsexternal_infoNANA17668390
RHOAhsa-miR-155-3pMirecordsexternal_info{unchanged}NA18794355
ETS1hsa-miR-155-3pMirecordsexternal_infoNANA18950466
MEIS1hsa-miR-155-3pMirecordsexternal_info{unchanged}NA18950466
TAB2hsa-miR-155-3pMirecordsexternal_infoNANA19193853
CCN1hsa-miR-155-3pMirecordsexternal_info{changed}NA20452491
MYD88hsa-miR-155-3pMirecordsexternal_info{unchanged}NA20219467
FOXO3hsa-miR-155-3pMirecordsexternal_info{unchanged}NA20371610
SOCS1hsa-miR-155-3pMirecordsexternal_info{changed}NA20354188
FGF7hsa-miR-155-3pMirecordsexternal_infoNANA19701459
IKBKEhsa-miR-155-3pMirecordsexternal_info{changed}NA19650740
FADDhsa-miR-155-3pMirecordsexternal_info{unchanged}NA19650740
MECP2hsa-miR-155-3pMirecordsexternal_info{changed}NA19897480
CCND1hsa-miR-155-3pMirecordsexternal_infoNANA19538740
SPI1hsa-miR-155-3pMirecordsexternal_infoNANA19386588
UQCRFS1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI20550618
MEIS1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI18950466
MEIS1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)18668040
TAB2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI19193853
TAB2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI20852130
TAB2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23449975
TAB2hsa-miR-155-5pMirtarbaseexternal_infoReporter assayFunctional MTI20680360
TAB2hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherNon-Functional MTI20584899
MECP2hsa-miR-155-5pMirtarbaseexternal_infoImmunohistochemistry//Luciferase reporter assay//qFunctional MTI19897480
MECP2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//MicroarrayFunctional MTI20388499
SOCS1hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI20354188
SOCS1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI22387553
SOCS1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22771905
MSH6hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blot//Northern Functional MTI20351277
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI19890474
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blot//Reporter Functional MTI20041145
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;Western Functional MTI19359473
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoGFP reporter assay//Luciferase reporter assay//NorFunctional MTI19641183
DET1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI18367535
DET1hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI20584899
SMAD5hsa-miR-155-5pMirtarbaseexternal_infoimmunoblot//Luciferase reporter assay//qRT-PCR//WeFunctional MTI20133617
SMAD5hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI20427544
ZIC3hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19177201
BACH1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCRFunctional MTI19193853
BACH1hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assayFunctional MTI18299402
BACH1hsa-miR-155-5pMirtarbaseexternal_infoImmunohistochemistry//In situ hybridization//LucifFunctional MTI21541331
BACH1hsa-miR-155-5pMirtarbaseexternal_infoReporter assayFunctional MTI17881434
ARNTLhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)20584899
CSF1Rhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)20452491
CEBPBhsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI18299402
JARID2hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assayFunctional MTI19759154
JARID2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23185331
CSNK1A1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22350414
APChsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19136465
WDFY1hsa-miR-155-5pMirtarbaseexternal_infopSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
UBE2J1hsa-miR-155-5pMirtarbaseexternal_infopSILAC//ProteomicsFunctional MTI (Weak)18668040
PRAF2hsa-miR-155-5pMirtarbaseexternal_infopSILACFunctional MTI (Weak)18668040
PDLIM5hsa-miR-155-5pMirtarbaseexternal_infoWestern blotFunctional MTI20584899
MSI2hsa-miR-155-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI20584899
DNAJC19hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)20584899
CEBPBhsa-miR-155-5pMirtarbaseexternal_infoMicroarray//qRT-PCR//Western blotFunctional MTI19193853
CEBPBhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19596814
CEBPBhsa-miR-155-5pMirtarbaseexternal_infoELISA//Immunoblot//Immunocytochemistry//ImmunofluoFunctional MTI19887047
CDK5RAP3hsa-miR-155-5pMirtarbaseexternal_infoProteomics;OtherFunctional MTI (Weak)20584899
BRPF3hsa-miR-155-5pMirtarbaseexternal_infoProteomics//Western blotFunctional MTI17668390
BRPF3hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)17588946
BRPF3hsa-miR-155-5pMirtarbaseexternal_infoProteomics;OtherFunctional MTI (Weak)16675453
TM6SF1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI17881434
JADE1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherNon-Functional MTI17881434
RHOAhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI18794355
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assayFunctional MTI17668390
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Real time PCR//ReporterFunctional MTI17588946
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Quantitative pFunctional MTI20735984
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blot//Functional MTI16675453
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoWestern blotFunctional MTI21310411
PKIAhsa-miR-155-5pMirtarbaseexternal_infoChIP-seq//Immunoblot//Luciferase reporter assay//qFunctional MTI22473996
TP53INP1hsa-miR-155-5pMirtarbaseexternal_infoWestern blot//Luciferase reporter assay//Reporter Functional MTI17911264
TP53INP1hsa-miR-155-5pMirtarbaseexternal_infoMicroarray//qRT-PCR//Western blotFunctional MTI21093163
IKBKEhsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI18753206
FGF7hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19701459
KDM3Ahsa-miR-155-5pMirtarbaseexternal_infoIn situ hybridization//Luciferase reporter assay//Functional MTI21541331
NFATC2IPhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayNon-Functional MTI17881434
CUX1hsa-miR-155-5pMirtarbaseexternal_infoMicroarray//qRT-PCRFunctional MTI (Weak)19193853
BCAT1hsa-miR-155-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)19193853
SPI1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19386588
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI19359473
EDN1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19783678
FOXO3hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI20371610
FOXO3hsa-miR-155-5pMirtarbaseexternal_infoFlow//Immunoblot//Immunofluorescence//ImmunohistocFunctional MTI21304824
FOXO3hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19650740
JUNhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI22508041
IFNGR1hsa-miR-155-5pMirtarbaseexternal_infoFlow//Luciferase reporter assay//Northern blotFunctional MTI19877012
ETS1hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;Western blot;qRT-PCRFunctional MTI21310411
FLI1hsa-miR-155-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI18950466
CCN1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI20452491
ICAM1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayNon-Functional MTI19949084
ICAM1hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)21310411
SMAD2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blot//Functional MTI21036908
MYBhsa-miR-155-5pMirtarbaseexternal_infoImmunohistochemistry//Luciferase reporter assay//NFunctional MTI21062812
SKIhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21466664
GCSAMhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI22096245
IL13RA1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21097505
BCL6hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23041630
MAP3K10hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23189122
MAP3K10hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23555551
NOS3hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI23108656
MYD88hsa-miR-155-5pMirtarbaseexternal_infoWestern blotFunctional MTI21030878
SMAD4hsa-miR-155-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI21036908
MAP3K14hsa-miR-155-5pMirtarbaseexternal_infoReporter assayFunctional MTI20584899
EEF1E1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19136465
AGRNhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)17881434
CCR9hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19193853
RSF1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)20209161
PDPRhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)20371610
FAM120Ahsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)18262046
CDH2hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19386588
TNPO1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)21310411
GSK3Bhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19289835
ADAM10hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)21030878
NSD3hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI21030878
MASTLhsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI18668040
E2F2hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherNon-Functional MTI19759154
FAM135Ahsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI18950466
FAM135Ahsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherNon-Functional MTI21310411
C3orf18hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI21036908
C3orf18hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;Western blotFunctional MTI20584899
SYPL1hsa-miR-155-5pTarbaseexternal_infoProteomicsPOSITIVE
TM6SF1hsa-miR-155-5pTarbaseexternal_infoReporter GenePOSITIVE
JADE1hsa-miR-155-5pTarbaseexternal_infoReporter GeneNEGATIVE
XAF1hsa-miR-155-5pTarbaseexternal_infoOtherPOSITIVE
SMAD3hsa-miR-155-5pTarbaseexternal_infoWesternblitNEGATIVE
ICAM1hsa-miR-155-5pTarbaseexternal_infoqPCRPOSITIVE
CD36hsa-miR-155-5pTarbaseexternal_infoWesternblitPOSITIVE
HDAC4hsa-miR-155-5pOncomiRDBexternal_infoNANA23169640
CDC73hsa-miR-155-5pOncomiRDBexternal_infoNANA23166327
APAF1hsa-miR-155-5pOncomiRDBexternal_infoNANA22996741
PIK3R1hsa-miR-155-5pOncomiRDBexternal_infoNANA22609116
SMAD2hsa-miR-155-5pOncomiRDBexternal_infoNANA22426647
CSNK1A1hsa-miR-155-5pOncomiRDBexternal_infoNANA22350414
BCL2hsa-miR-155-5pOncomiRDBexternal_infoNANA22139839
GCSAMhsa-miR-155-5pOncomiRDBexternal_infoNANA22096245
SOX6hsa-miR-155-5pOncomiRDBexternal_infoNANA21989846
PPP2CAhsa-miR-155-5pOncomiRDBexternal_infoNANA21806946
STAB1hsa-miR-155-5pOncomiRDBexternal_infoNANA21743493
KDM3Ahsa-miR-155-5pOncomiRDBexternal_infoNANA21541331
SKIhsa-miR-155-5pOncomiRDBexternal_infoNANA21466664

Predicted Targets
Summary Value
Count of predictions:21661
Count of gene targets:8369
Count of transcripts:15886
Interacting mature miRNAs:hsa-miR-155-3p, hsa-miR-155-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENST00000385060
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl2125,573,980 - 25,574,044 (+)Ensembl
RefSeq Acc Id: NR_030784
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382125,573,980 - 25,574,044 (+)NCBI
GRCh372126,946,292 - 26,946,356 (+)ENTREZGENE
HuRef2112,349,435 - 12,349,499 (+)ENTREZGENE
CHM1_12126,506,960 - 26,507,024 (+)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000050445] Chr21:7749532..46670405 [GRCh38]
Chr21:15499847..48090317 [GRCh37]
Chr21:14421718..46914745 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic|conflicting interpretations of pathogenicity|conflicting data from submitters
GRCh38/hg38 21q11.2-21.3(chr21:13194345-29257208)x1 copy number loss See cases [RCV000052798] Chr21:13194345..29257208 [GRCh38]
Chr21:14566666..30629529 [GRCh37]
Chr21:13488537..29551400 [NCBI36]
Chr21:21q11.2-21.3
pathogenic
GRCh38/hg38 21q11.2-22.11(chr21:14000720-30903065)x1 copy number loss See cases [RCV000052799] Chr21:14000720..30903065 [GRCh38]
Chr21:15373041..32275384 [GRCh37]
Chr21:14294912..31197255 [NCBI36]
Chr21:21q11.2-22.11
pathogenic
GRCh38/hg38 21q21.2-21.3(chr21:24292832-27046585)x1 copy number loss See cases [RCV000052804] Chr21:24292832..27046585 [GRCh38]
Chr21:25665145..28418904 [GRCh37]
Chr21:24587016..27340775 [NCBI36]
Chr21:21q21.2-21.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46653090)x3 copy number gain See cases [RCV000053040] Chr21:7749532..46653090 [GRCh38]
Chr21:14539679..48073002 [GRCh37]
Chr21:13461550..46897430 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053042] Chr21:7749532..46623792 [GRCh38]
Chr21:14595524..48043704 [GRCh37]
Chr21:13517395..46868132 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053043] Chr21:7749532..46623792 [GRCh38]
Chr21:14629063..48043704 [GRCh37]
Chr21:13550934..46868132 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670546)x3 copy number gain See cases [RCV000053045] Chr21:7749532..46670546 [GRCh38]
Chr21:15499647..48090458 [GRCh37]
Chr21:14421518..46914886 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46661140)x3 copy number gain See cases [RCV000053065] Chr21:7749532..46661140 [GRCh38]
Chr21:15499647..48081052 [GRCh37]
Chr21:14421518..46905480 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46661140)x3 copy number gain See cases [RCV000053067] Chr21:7749532..46661140 [GRCh38]
Chr21:15499847..48081052 [GRCh37]
Chr21:14421718..46905480 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000053068] Chr21:7749532..46670405 [GRCh38]
Chr21:20655360..48090317 [GRCh37]
Chr21:19577231..46914745 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053039] Chr21:7749532..46623792 [GRCh38]
Chr21:14524963..48043704 [GRCh37]
Chr21:13446834..46868132 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q22.11-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000135310] Chr21:7749532..46670346 [GRCh38]
Chr21:34111831..48090258 [GRCh37]
Chr21:33033702..46914686 [NCBI36]
Chr21:21q22.11-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-42971047)x3 copy number gain See cases [RCV000133676] Chr21:7749532..42971047 [GRCh38]
Chr21:15499847..44391157 [GRCh37]
Chr21:14421718..43264226 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46653084)x3 copy number gain See cases [RCV000134727] Chr21:7749532..46653084 [GRCh38]
Chr21:15485038..48072996 [GRCh37]
Chr21:14406909..46897424 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46649831)x3 copy number gain See cases [RCV000134509] Chr21:7749532..46649831 [GRCh38]
Chr21:14577835..48069743 [GRCh37]
Chr21:13499706..46894171 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670440)x3 copy number gain See cases [RCV000134119] Chr21:7749532..46670440 [GRCh38]
Chr21:15485038..48090352 [GRCh37]
Chr21:14406909..46914780 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46664250)x3 copy number gain See cases [RCV000134836] Chr21:7749532..46664250 [GRCh38]
Chr21:15485038..48084162 [GRCh37]
Chr21:14406909..46908590 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670440)x3 copy number gain See cases [RCV000134842] Chr21:7749532..46670440 [GRCh38]
Chr21:15513244..48090352 [GRCh37]
Chr21:14435115..46914780 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46660999)x3 copy number gain See cases [RCV000135448] Chr21:7749532..46660999 [GRCh38]
Chr21:15499847..48080911 [GRCh37]
Chr21:14421718..46905339 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000137255] Chr21:7749532..46671060 [GRCh38]
Chr21:35319225..48090972 [GRCh37]
Chr21:34241095..46915400 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000137337] Chr21:7749532..46671060 [GRCh38]
Chr21:10697897..48090972 [GRCh37]
Chr21:1..46915400 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.13(chr21:7749532-37653653)x1 copy number loss See cases [RCV000138095] Chr21:7749532..37653653 [GRCh38]
Chr21:15451032..39025955 [GRCh37]
Chr21:14372903..37947825 [NCBI36]
Chr21:21p11.2-q22.13
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000138216] Chr21:7749532..46671060 [GRCh38]
Chr21:10944001..48090972 [GRCh37]
Chr21:9965872..46915400 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000138436] Chr21:7749532..46671060 [GRCh38]
Chr21:15451032..48090972 [GRCh37]
Chr21:14372903..46915400 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic|conflicting data from submitters
GRCh38/hg38 21q21.1-21.3(chr21:22270514-27695129)x1 copy number loss See cases [RCV000138937] Chr21:22270514..27695129 [GRCh38]
Chr21:23642834..29067448 [GRCh37]
Chr21:22564705..27989319 [NCBI36]
Chr21:21q21.1-21.3
likely pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000140103] Chr21:7749532..46670346 [GRCh38]
Chr21:14577894..48090258 [GRCh37]
Chr21:13499765..46914686 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46698247)x3 copy number gain See cases [RCV000141346] Chr21:7749532..46698247 [GRCh38]
Chr21:14577835..48118159 [GRCh37]
Chr21:13499706..46942587 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7817158-46670440)x1 copy number loss See cases [RCV000142427] Chr21:7817158..46670440 [GRCh38]
Chr21:15485038..48090352 [GRCh37]
Chr21:14406909..46914780 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q21.1-22.11(chr21:19423169-31841150)x1 copy number loss See cases [RCV000142217] Chr21:19423169..31841150 [GRCh38]
Chr21:20795486..33213462 [GRCh37]
Chr21:19717357..32135333 [NCBI36]
Chr21:21q21.1-22.11
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000143376] Chr21:7749532..46677460 [GRCh38]
Chr21:15006458..48097372 [GRCh37]
Chr21:13928329..46921800 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460) copy number gain See cases [RCV000143160] Chr21:7749532..46677460 [GRCh38]
Chr21:14386013..48097372 [GRCh37]
Chr21:13307884..46921800 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000143120] Chr21:7749532..46677460 [GRCh38]
Chr21:15006457..48097372 [GRCh37]
Chr21:13928328..46921800 [NCBI36]
Chr21:21q11.2-22.3
pathogenic
GRCh38/hg38 21q11.2-21.3(chr21:13634137-27862841)x1 copy number loss See cases [RCV000143749] Chr21:13634137..27862841 [GRCh38]
Chr21:15006458..29235160 [GRCh37]
Chr21:13928329..28157031 [NCBI36]
Chr21:21q11.2-21.3
pathogenic
NC_000021.7:g.13636378_28138533dup duplication Alzheimer disease [RCV000148341] Chr21:14714507..29216662 [GRCh37]
Chr21:13636378..28138533 [NCBI36]
Chr21:21q11.2-21.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000148131] Chr21:7749532..46670405 [GRCh38]
Chr21:15499847..48090317 [GRCh37]
Chr21:14421718..46914745 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000053069] Chr21:7749532..46670405 [GRCh38]
Chr21:34423268..48090317 [GRCh37]
Chr21:33345138..46914745 [NCBI36]
Chr21:21p11.2-q22.3
pathogenic
GRCh38/hg38 21q21.3-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000141827] Chr21:7749532..46677460 [GRCh38]
Chr21:28285299..48097372 [GRCh37]
Chr21:27207170..46921800 [NCBI36]
Chr21:21q21.3-22.3
uncertain significance
GRCh38/hg38 21q11.2-21.3(chr21:14000146-27785985) copy number loss Monosomy 21 [RCV000225561] Chr21:14000146..27785985 [GRCh38]
Chr21:21q11.2-21.3
pathogenic
GRCh38/hg38 21p11.2-q21.3(chr21:13048294-27532614) copy number loss Monosomy 21 [RCV000225452] Chr21:13048294..27532614 [GRCh38]
Chr21:21p11.2-q21.3
pathogenic
GRCh38/hg38 21q21.1-22.11(chr21:21754822-32380347) copy number loss Monosomy 21 [RCV000225665] Chr21:21754822..32380347 [GRCh38]
Chr21:21q21.1-22.11
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15538655-48080926)x1 copy number loss See cases [RCV000239948] Chr21:15538655..48080926 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15410701-48090317)x3 copy number gain See cases [RCV000240397] Chr21:15410701..48090317 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-43598570)x3 copy number gain See cases [RCV000446716] Chr21:15006457..43598570 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:14771770-48080867)x3 copy number gain See cases [RCV000447884] Chr21:14771770..48080867 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-44827632)x3 copy number gain See cases [RCV000448199] Chr21:15006457..44827632 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15285841-48097372)x3 copy number gain See cases [RCV000447729] Chr21:15285841..48097372 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain See cases [RCV000447749] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q11.2-21.3(chr21:15006457-29225300)x1 copy number loss See cases [RCV000510539] Chr21:15006457..29225300 [GRCh37]
Chr21:21q11.2-21.3
pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006458-48097372) copy number gain See cases [RCV000511589] Chr21:15006458..48097372 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10827533-48100155)x3 copy number gain not provided [RCV000741419] Chr21:10827533..48100155 [GRCh37]
Chr21:21p11.2-q22.3
pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10699330-48117896)x3 copy number gain not provided [RCV000741413] Chr21:10699330..48117896 [GRCh37]
Chr21:21p11.2-q22.3
pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10704198-48117896)x3 copy number gain not provided [RCV000741415] Chr21:10704198..48117896 [GRCh37]
Chr21:21p11.2-q22.3
pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10824040-48090629)x3 copy number gain not provided [RCV000741418] Chr21:10824040..48090629 [GRCh37]
Chr21:21p11.2-q22.3
pathogenic
GRCh37/hg19 21q11.2-21.3(chr21:15006457-29325923)x1 copy number loss not provided [RCV001007109] Chr21:15006457..29325923 [GRCh37]
Chr21:21q11.2-21.3
pathogenic
Single allele duplication Neurodevelopmental disorder [RCV000787411] Chr21:14374186..29305180 [GRCh37]
Chr21:21q11.2-21.3
likely pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain not provided [RCV000846937] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3
pathogenic
GRCh37/hg19 21q21.3(chr21:26908459-27358327)x3 copy number gain not provided [RCV000848217] Chr21:26908459..27358327 [GRCh37]
Chr21:21q21.3
uncertain significance
GRCh37/hg19 21q11.2-22.3(chr21:14629063-48090317)x3 copy number gain See cases [RCV001263025] Chr21:14629063..48090317 [GRCh37]
Chr21:21q11.2-22.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31542 AgrOrtholog
COSMIC MIR155 COSMIC
Ensembl Genes ENSG00000283904 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000385060 ENTREZGENE
GTEx ENSG00000283904 GTEx
HGNC ID HGNC:31542 ENTREZGENE
Human Proteome Map MIR155 Human Proteome Map
miRBase MI0000681 ENTREZGENE
NCBI Gene 406947 ENTREZGENE
OMIM 609337 OMIM
PharmGKB PA164722515 PharmGKB
RNAcentral URS000034309A RNACentral
  URS000062749E RNACentral
  URS0000D54CAD RNACentral