MIR155 (microRNA 155) - Rat Genome Database

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Gene: MIR155 (microRNA 155) Homo sapiens
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Symbol: MIR155
Name: microRNA 155
RGD ID: 2299183
HGNC Page HGNC:31542
Description: Enables mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Involved in miRNA-mediated post-transcriptional gene silencing. Predicted to be part of RISC complex. Implicated in colon adenocarcinoma; hepatocellular carcinoma; oropharynx cancer; and type 1 diabetes mellitus. Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and pancreatic carcinoma (multiple).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-155; MIRN155; miRNA155
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382125,573,980 - 25,574,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2125,573,980 - 25,574,044 (+)EnsemblGRCh38hg38GRCh38
GRCh372126,946,292 - 26,946,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera2112,129,700 - 12,129,764 (+)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2112,349,435 - 12,349,499 (+)NCBIHuRef
CHM1_12126,506,960 - 26,507,024 (+)NCBICHM1_1
T2T-CHM13v2.02123,931,556 - 23,931,620 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (ISO)
Acute Lung Injury  (ISO)
acute myeloid leukemia  (IEP)
acute myocardial infarction  (IEP)
acute pancreatitis  (IEP)
adult respiratory distress syndrome  (IEP)
Albuminuria  (EXP)
Alcoholic Fatty Liver  (ISO)
alcoholic hepatitis  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic contact dermatitis  (ISO)
Alzheimer's disease  (IAGP)
Alzheimer's Disease, Early-Onset, with Cerebral Amyloid Angiopathy  (IAGP)
Angina Pectoris  (IEP)
Arsenic Poisoning  (IEP)
atherosclerosis  (IEP,ISO)
atrophic gastritis  (ISO)
autoimmune hepatitis  (IEP,ISO)
Behcet's disease  (IEP)
biliary atresia  (IEP)
Carcinoid Tumor  (EXP)
Chemical and Drug Induced Liver Injury  (ISO)
cholangiocarcinoma  (IEP)
cholera  (IEP)
Chronic Hepatitis B  (IEP)
Chronic Hepatitis C  (IEP)
chronic lymphocytic leukemia  (IEP)
Chronic Periodontitis  (IEP)
colon adenocarcinoma  (IMP)
colon cancer  (IEP,ISO)
Colonic Polyps  (ISO)
colorectal cancer  (IEP)
coronary artery disease  (IEP)
Crohn's disease  (IEP)
cystic fibrosis  (IEP)
Down syndrome  (EXP)
encephalomyelitis  (ISO)
Endotoxemia  (ISO)
Endotoxin Hyporesponsiveness  (ISO)
esophageal cancer  (IEP)
Experimental Colitis  (ISO)
Experimental Mammary Neoplasms  (IDA,IMP)
familial adenomatous polyposis  (IEP)
Fibrosis  (ISO)
Flaviviridae Infections  (IEP)
gallbladder carcinoma  (IEP)
gastritis  (IEP)
head and neck squamous cell carcinoma  (IEP)
Helicobacter Infections  (IEP,ISO)
hepatitis B  (IEP)
hepatocellular carcinoma  (IAGP,IEP,IMP)
hyperglycemia  (ISO)
Insulin Resistance  (IEP,ISO)
Intervertebral Disc Disease  (IEP,ISO)
Intestinal Reperfusion Injury  (ISO)
liposarcoma  (IEP)
liver cirrhosis  (IEP)
Liver Injury  (ISO)
Liver Metastasis  (IEP)
Liver Reperfusion Injury  (ISO)
Lung Neoplasms  (EXP)
Lymphatic Metastasis  (IEP)
lymphoma  (ISS)
metabolic dysfunction-associated steatotic liver disease  (IEP,ISO)
Microsatellite Instability  (EXP)
multiple myeloma  (IEP)
myocardial infarction  (ISO)
Neoplasm Invasiveness  (EXP)
Neoplasm Metastasis  (EXP,IEP)
Neoplastic Cell Transformation  (EXP)
Neurodevelopmental Disorders  (IAGP)
obesity  (IEP,ISO)
Oral Lichen Planus  (IEP)
oral squamous cell carcinoma  (IEP)
oropharynx cancer  (IDA)
pancreatic carcinoma  (IEP)
pancreatic ductal adenocarcinoma  (IEP)
pancreatitis  (EXP)
Parkinson's disease  (ISO)
Pediatric Crohn's Disease  (IEP)
peritonitis  (ISO)
pre-eclampsia  (IEP)
primary sclerosing cholangitis  (IEP)
prostate cancer  (IEP)
rheumatic heart disease  (ISO)
salivary gland adenoid cystic carcinoma  (IEP)
Sepsis  (IEP,ISO)
Septic Peritonitis  (IEP)
severe pre-eclampsia  (IEP)
stomach cancer  (IEP)
tongue cancer  (IEP)
toxic shock syndrome  (IEP)
transient cerebral ischemia  (ISO)
traumatic brain injury  (ISO)
type 1 diabetes mellitus  (IAGP)
type 2 diabetes mellitus  (IEP)
ulcerative colitis  (IEP)
visceral leishmaniasis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,5-hexanedione  (ISO)
2-acetamidofluorene  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
all-trans-retinoic acid  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
Bandrowski's base  (EXP)
benzo[a]pyrene diol epoxide I  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP)
cannabidiol  (ISO)
carbamazepine  (EXP)
carbon atom  (EXP)
carboplatin  (EXP)
chloroquine  (EXP)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clopidogrel  (EXP)
cypermethrin  (ISO)
Deoxycorticosterone acetate  (ISO)
desferrioxamine B  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
doxorubicin  (EXP)
elemental carbon  (EXP)
fluoranthene  (ISO)
folic acid  (ISO)
galaxolide  (EXP)
gentamycin  (ISO)
hydrogen peroxide  (EXP)
hydroquinone  (EXP)
isoprenaline  (ISO)
isorhamnetin  (ISO)
L-methionine  (ISO)
lamotrigine  (EXP)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
mechlorethamine  (ISO)
metformin  (ISO)
methamidophos  (EXP)
methanol  (ISO)
morphine  (EXP)
Octicizer  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
piperacillin  (EXP)
poly(I:C)  (ISO)
progesterone  (EXP,ISO)
propofol  (ISO)
puromycin  (ISO)
quercetin  (ISO)
resveratrol  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
Sinomenine  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
streptozocin  (ISO)
sulfamethoxazole  (EXP)
sulfur dioxide  (EXP)
T-2 toxin  (ISO)
tert-butyl hydroperoxide  (EXP)
tetrachloromethane  (ISO)
trichostatin A  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Evaluation of the miRNA-146a and miRNA-155 Expression Levels in Patients with Oral Lichen Planus. Ahmadi-Motamayel F, etal., Iran J Immunol. 2017 Dec;14(4):316-324. doi: IJIv14i4A6.
2. Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli. Alexander M, etal., J Immunol. 2017 Nov 15;199(10):3559-3570. doi: 10.4049/jimmunol.1700904. Epub 2017 Oct 4.
3. Long non-coding RNA CCAT1 is overexpressed in oral squamous cell carcinomas and predicts poor prognosis. Arunkumar G, etal., Biomed Rep. 2017 Apr;6(4):455-462. doi: 10.3892/br.2017.876. Epub 2017 Mar 17.
4. Polymorphisms in genes encoding miR-155 and miR-146a are associated with protection to type 1 diabetes mellitus. Assmann TS, etal., Acta Diabetol. 2017 May;54(5):433-441. doi: 10.1007/s00592-016-0961-y. Epub 2017 Jan 19.
5. The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis. Bala S, etal., J Hepatol. 2016 Jun;64(6):1378-87. doi: 10.1016/j.jhep.2016.01.035. Epub 2016 Feb 8.
6. MicroRNA-155, -185 and -193b as biomarkers in human papillomavirus positive and negative tonsillar and base of tongue squamous cell carcinoma. Bersani C, etal., Oral Oncol. 2018 Jul;82:8-16. doi: 10.1016/j.oraloncology.2018.04.021. Epub 2018 May 4.
7. MicroRNA-155 potentiates the inflammatory response in hypothermia by suppressing IL-10 production. Billeter AT, etal., FASEB J. 2014 Dec;28(12):5322-36. doi: 10.1096/fj.14-258335. Epub 2014 Sep 17.
8. Induction of immunomodulatory miR-146a and miR-155 in small intestinal epithelium of Vibrio cholerae infected patients at acute stage of cholera. Bitar A, etal., PLoS One. 2017 Mar 20;12(3):e0173817. doi: 10.1371/journal.pone.0173817. eCollection 2017.
9. Expression of microRNA-155 in inflammatory cells modulates liver injury. Blaya D, etal., Hepatology. 2018 Aug;68(2):691-706. doi: 10.1002/hep.29833. Epub 2018 May 2.
10. Up-regulated expression of miR-155 in human colonic cancer. Cao H, etal., J Cancer Res Ther. 2018 Apr-Jun;14(3):604-607. doi: 10.4103/0973-1482.175432.
11. MiR-155 controls follicular Treg cell-mediated humoral autoimmune intestinal injury by inhibiting CTLA-4 expression. Chao G, etal., Int Immunopharmacol. 2019 Jun;71:267-276. doi: 10.1016/j.intimp.2019.03.009. Epub 2019 Mar 28.
12. Inhibition of miR‑155‑5p attenuates the valvular damage induced by rheumatic heart disease. Chen A, etal., Int J Mol Med. 2020 Feb;45(2):429-440. doi: 10.3892/ijmm.2019.4420. Epub 2019 Dec 6.
13. NF-kB-regulated exosomal miR-155 promotes the inflammation associated with arsenite carcinogenesis. Chen C, etal., Cancer Lett. 2017 Mar 1;388:21-33. doi: 10.1016/j.canlet.2016.11.027. Epub 2016 Nov 30.
14. Long Non-Coding RNA CCAT1 Acts as a Competing Endogenous RNA to Regulate Cell Growth and Differentiation in Acute Myeloid Leukemia. Chen L, etal., Mol Cells. 2016 Apr 30;39(4):330-6. doi: 10.14348/molcells.2016.2308. Epub 2016 Feb 26.
15. Overexpression of IL-9 induced by STAT3 phosphorylation is mediated by miR-155 and miR-21 in chronic lymphocytic leukemia. Chen N, etal., Oncol Rep. 2018 Jun;39(6):3064-3072. doi: 10.3892/or.2018.6367. Epub 2018 Apr 12.
16. Differential Expression of MicroRNAs in Hepatitis C Virus-Mediated Liver Disease Between African Americans and Caucasians: Implications for Racial Health Disparities. Devhare PB, etal., Gene Expr. 2017 Feb 10;17(2):89-98. doi: 10.3727/105221616X693594. Epub 2016 Oct 19.
17. MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic disease. Dickey LL, etal., J Neuroinflammation. 2016 Sep 7;13(1):240. doi: 10.1186/s12974-016-0699-z.
18. Circulating microRNA-155 is associated with insulin resistance in chronic hepatitis C patients. El Samaloty NM, etal., Arab J Gastroenterol. 2019 Mar;20(1):1-7. doi: 10.1016/j.ajg.2019.01.011. Epub 2019 Mar 7.
19. Increased Levels of miR-155 are Related to Higher T-Cell Activation in the Peripheral Blood of Patients with Chronic Hepatitis B. Fang J, etal., Genet Test Mol Biomarkers. 2019 Feb;23(2):118-123. doi: 10.1089/gtmb.2018.0092.
20. MicroRNA Profiling and Target Genes Related to Metastasis of Salivary Adenoid Cystic Carcinoma. Feng X, etal., Anticancer Res. 2017 Jul;37(7):3473-3481. doi: 10.21873/anticanres.11715.
21. Deregulation of MicroRNAs in Gastric Lymphomagenesis Induced in the d3Tx Mouse Model of Helicobacter pylori Infection. Floch P, etal., Front Cell Infect Microbiol. 2017 May 16;7:185. doi: 10.3389/fcimb.2017.00185. eCollection 2017.
22. MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies. Gan L, etal., Medicine (Baltimore). 2017 Jul;96(28):e7515. doi: 10.1097/MD.0000000000007515.
23. MicroRNA-155 increases colon cancer chemoresistance to cisplatin by targeting forkhead box O3. Gao Y, etal., Oncol Lett. 2018 Apr;15(4):4781-4788. doi: 10.3892/ol.2018.7976. Epub 2018 Feb 7.
24. Early diagnostic role of PSA combined miR-155 detection in prostate cancer. Guo T, etal., Eur Rev Med Pharmacol Sci. 2018 Mar;22(6):1615-1621. doi: 10.26355/eurrev_201803_14568.
25. MicroRNA-31 and MicroRNA-155 Are Overexpressed in Ulcerative Colitis and Regulate IL-13 Signaling by Targeting Interleukin 13 Receptor α-1. Gwiggner M, etal., Genes (Basel). 2018 Feb 13;9(2). pii: genes9020085. doi: 10.3390/genes9020085.
26. Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect. Harrison EB, etal., Front Mol Neurosci. 2017 Jul 28;10:228. doi: 10.3389/fnmol.2017.00228. eCollection 2017.
27. MiR-200b and miR-155 as predictive biomarkers for the efficacy of chemoradiation in locally advanced head and neck squamous cell carcinoma. Hess AK, etal., Eur J Cancer. 2017 May;77:3-12. doi: 10.1016/j.ejca.2017.02.018. Epub 2017 Mar 26.
28. Effect of microRNA-155 on the interferon-gamma signaling pathway in biliary atresia. Hsu YA, etal., Chin J Physiol. 2016 Dec 31;59(6):315-322. doi: 10.4077/CJP.2016.BAE419.
29. MicroRNA-155 inhibition attenuates endoplasmic reticulum stress-induced cardiomyocyte apoptosis following myocardial infarction via reducing macrophage inflammation. Hu J, etal., Eur J Pharmacol. 2019 Aug 15;857:172449. doi: 10.1016/j.ejphar.2019.172449. Epub 2019 Jun 14.
30. MiR-155 and its functional variant rs767649 contribute to the susceptibility and survival of hepatocellular carcinoma. Ji J, etal., Oncotarget. 2016 Sep 13;7(37):60303-60309. doi: 10.18632/oncotarget.11206.
31. MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene. Jiang S, etal., Cancer Res. 2010 Apr 15;70(8):3119-27. doi: 10.1158/0008-5472.CAN-09-4250. Epub 2010 Mar 30.
32. MicroRNA-155 as a proinflammatory regulator via SHIP-1 down-regulation in acute gouty arthritis. Jin HM, etal., Arthritis Res Ther. 2014 Apr 7;16(2):R88. doi: 10.1186/ar4531.
33. [In vivo imaging of breast tumors by a 99mTc radiolabeled probe targeting microRNA-155 in mice models]. Kang L, etal., Beijing Da Xue Xue Bao Yi Xue Ban. 2018 Apr 18;50(2):326-330.
34. Assessing the clinical value of microRNAs in formalin-fixed paraffin-embedded liposarcoma tissues: Overexpressed miR-155 is an indicator of poor prognosis. Kapodistrias N, etal., Oncotarget. 2017 Jan 24;8(4):6896-6913. doi: 10.18632/oncotarget.14320.
35. Potential Oncogenic Role and Prognostic Implication of MicroRNA-155-5p in Oral Squamous Cell Carcinoma. Kim H, etal., Anticancer Res. 2018 Sep;38(9):5193-5200. doi: 10.21873/anticanres.12842.
36. Determination of mir-155 and mir-146a expression rates and its association with expression level of TNF-α and CTLA4 genes in patients with Behcet's disease. Kolahi S, etal., Immunol Lett. 2018 Dec;204:55-59. doi: 10.1016/j.imlet.2018.10.012. Epub 2018 Oct 23.
37. Insights into epigenetic regulation of microRNA-155 expression in multiple myeloma. Krzeminski P, etal., Biochim Biophys Acta. 2015 Mar;1849(3):353-66. doi: 10.1016/j.bbagrm.2014.12.002. Epub 2014 Dec 11.
38. [Value of serum miR-155-5p and miR-133a-3p expression for the diagnosis and prognosis evaluation of sepsis]. Lan C, etal., Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2016 Aug;28(8):694-8. doi: 10.3760/cma.j.issn.2095-4352.2016.08.005.
39. The tumor suppressor role of miR-155-5p in gastric cancer. Li S, etal., Oncol Lett. 2018 Aug;16(2):2709-2714. doi: 10.3892/ol.2018.8932. Epub 2018 Jun 8.
40. Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy. Li Y, etal., Int J Nanomedicine. 2018 Mar 1;13:1241-1256. doi: 10.2147/IJN.S158290. eCollection 2018.
41. MicroRNA-155 Deficiency in Kupffer Cells Ameliorates Liver Ischemia-Reperfusion Injury in Mice. Li Y, etal., Transplantation. 2017 Jul;101(7):1600-1608. doi: 10.1097/TP.0000000000001765.
42. Rituximab May Cause Increased Hepatitis C Virus Viremia in Rheumatoid Arthritis Patients Through Declining Exosomal MicroRNA-155. Liao TL, etal., Arthritis Rheumatol. 2018 Aug;70(8):1209-1219. doi: 10.1002/art.40495. Epub 2018 Jun 27.
43. MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice. Lin X, etal., PLoS Genet. 2016 Oct 6;12(10):e1006308. doi: 10.1371/journal.pgen.1006308. eCollection 2016 Oct.
44. microRNA-155 Modulates Hepatic Stellate Cell Proliferation, Apoptosis, and Cell Cycle Progression in Rats With Alcoholic Hepatitis via the MAPK Signaling Pathway Through Targeting SOCS1. Liu D, etal., Front Pharmacol. 2020 Apr 7;11:270. doi: 10.3389/fphar.2020.00270. eCollection 2020.
45. MiR-155 Alleviates Septic Lung Injury by Inducing Autophagy Via Inhibition of Transforming Growth Factor-β-Activated Binding Protein 2. Liu F, etal., Shock. 2017 Jul;48(1):61-68. doi: 10.1097/SHK.0000000000000839.
46. The miR-124-p63 feedback loop modulates colorectal cancer growth. Liu K, etal., Oncotarget. 2017 Apr 25;8(17):29101-29115. doi: 10.18632/oncotarget.16248.
47. miR-155-5p is Negatively Associated with Acute Pancreatitis and Inversely Regulates Pancreatic Acinar Cell Progression by Targeting Rela and Traf3. Liu S, etal., Cell Physiol Biochem. 2018;51(4):1584-1599. doi: 10.1159/000495648. Epub 2018 Nov 29.
48. MiR-155 inhibition ameliorates 2, 4, 6-Trinitrobenzenesulfonic acid (TNBS)-induced experimental colitis in rat via influencing the differentiation of Th17 cells by Jarid2. Liu Y, etal., Int Immunopharmacol. 2018 Nov;64:401-410. doi: 10.1016/j.intimp.2018.09.007. Epub 2018 Sep 22.
49. Serum levels of miR-29, miR-122, miR-155 and miR-192 are elevated in patients with cholangiocarcinoma. Loosen SH, etal., PLoS One. 2019 Jan 17;14(1):e0210944. doi: 10.1371/journal.pone.0210944. eCollection 2019.
50. MicroRNA-155 promotes the pathogenesis of experimental colitis by repressing SHIP-1 expression. Lu ZJ, etal., World J Gastroenterol. 2017 Feb 14;23(6):976-985. doi: 10.3748/wjg.v23.i6.976.
51. MicroRNA-155 is upregulated in ascites in patients with spontaneous bacterial peritonitis. Lutz P, etal., Sci Rep. 2017 Jan 11;7:40556. doi: 10.1038/srep40556.
52. Anti-inflammatory effects of curcumin are associated with down regulating microRNA-155 in LPS-treated macrophages and mice. Ma F, etal., Pharm Biol. 2017 Dec;55(1):1263-1273. doi: 10.1080/13880209.2017.1297838.
53. Decreased Serum Level of miR-155 is Associated with Obesity and its Related Metabolic Traits. Mahdavi R, etal., Clin Lab. 2018 Jan 1;64(1):77-84. doi: 10.7754/Clin.Lab.2017.170618.
54. MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma. Mikamori M, etal., Sci Rep. 2017 Feb 15;7:42339. doi: 10.1038/srep42339.
55. miR-146a, miR-155, miR-370, and miR-708 Are CFTR-Dependent, Predicted FOXO1 Regulators and Change at Onset of CFRDs. Montanini L, etal., J Clin Endocrinol Metab. 2016 Dec;101(12):4955-4963. doi: 10.1210/jc.2016-2431. Epub 2016 Sep 30.
56. MicroRNA-155 regulates the Th17 immune response by targeting Ets-1 in Behçet's disease. Na SY, etal., Clin Exp Rheumatol. 2016 Sep-Oct;34(6 Suppl 102):S56-S63. Epub 2016 Apr 18.
57. MicroRNA-155 is essential for the T cell-mediated control of Helicobacter pylori infection and for the induction of chronic Gastritis and Colitis. Oertli M, etal., J Immunol. 2011 Oct 1;187(7):3578-86. doi: 10.4049/jimmunol.1101772. Epub 2011 Aug 31.
58. miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4. Prossomariti A, etal., Mol Cancer Res. 2018 Dec;16(12):1965-1976. doi: 10.1158/1541-7786.MCR-18-0115. Epub 2018 Aug 2.
59. MicroRNA-146a and microRNA-155 as novel crevicular fluid biomarkers for periodontitis in non-diabetic and type 2 diabetic patients. Radović N, etal., J Clin Periodontol. 2018 Jun;45(6):663-671. doi: 10.1111/jcpe.12888. Epub 2018 May 15.
60. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
61. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
62. Differential intestinal anti-inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and microbiota composition. Rodríguez-Nogales A, etal., Mol Nutr Food Res. 2017 Nov;61(11). doi: 10.1002/mnfr.201700144. Epub 2017 Aug 29.
63. Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson's Disease. Sancandi M, etal., Int J Mol Sci. 2020 Apr 15;21(8). pii: ijms21082743. doi: 10.3390/ijms21082743.
64. Role of 3-Acetyl-11-Keto-Beta-Boswellic Acid in Counteracting LPS-Induced Neuroinflammation via Modulation of miRNA-155. Sayed AS, etal., Mol Neurobiol. 2018 Jul;55(7):5798-5808. doi: 10.1007/s12035-017-0801-2. Epub 2017 Oct 27.
65. Circulating and Fecal microRNAs as Biomarkers for Inflammatory Bowel Diseases. Schönauen K, etal., Inflamm Bowel Dis. 2018 Jun 8;24(7):1547-1557. doi: 10.1093/ibd/izy046.
66. Serum MicroRNA-122 and MicroRNA-155: Markers of Disease Progression in Hepatitis C viral infection. Sheneef A, etal., Egypt J Immunol. 2017 Jun;24(2):33-46.
67. Increased duodenal expression of miR-146a and -155 in pediatric Crohn's disease. Szűcs D, etal., World J Gastroenterol. 2016 Jul 14;22(26):6027-35. doi: 10.3748/wjg.v22.i26.6027.
68. [Protective effect of microRNA-155 antisense oligonucleotid on lipopolysaccharide-induced acute lung injury in mice]. Tang J, etal., Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Aug;30(8):743-747. doi: 10.3760/cma.j.issn.2095-4352.2018.08.006.
69. Downregulation of miR-155 attenuates sepsis-induced acute lung injury by targeting SIRT1. Tuerdi B, etal., Int J Clin Exp Pathol. 2018 Sep 1;11(9):4483-4492. eCollection 2018.
70. Circulating Plasma Levels of miR-20b, miR-29b and miR-155 as Predictors of Bevacizumab Efficacy in Patients with Metastatic Colorectal Cancer. Ulivi P, etal., Int J Mol Sci. 2018 Jan 20;19(1). pii: ijms19010307. doi: 10.3390/ijms19010307.
71. MicroRNA 155 Contributes to Host Immunity against Leishmania donovani but Is Not Essential for Resolution of Infection. Varikuti S, etal., Infect Immun. 2019 Jul 23;87(8). pii: IAI.00307-19. doi: 10.1128/IAI.00307-19. Print 2019 Aug.
72. MicroRNA-155 Amplifies Nitric Oxide/cGMP Signaling and Impairs Vascular Angiotensin II Reactivity in Septic Shock. Vasques-Nóvoa F, etal., Crit Care Med. 2018 Sep;46(9):e945-e954. doi: 10.1097/CCM.0000000000003296.
73. MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer. Velazquez KT, etal., Am J Physiol Gastrointest Liver Physiol. 2016 Mar 15;310(6):G347-58. doi: 10.1152/ajpgi.00326.2015. Epub 2016 Jan 7.
74. miR155 deficiency aggravates high-fat diet-induced adipose tissue fibrosis in male mice. Velázquez KT, etal., Physiol Rep. 2017 Sep;5(18). pii: 5/18/e13412. doi: 10.14814/phy2.13412.
75. MicroRNA-155 Deficiency Leads to Decreased Atherosclerosis, Increased White Adipose Tissue Obesity, and Non-alcoholic Fatty Liver Disease: A NOVEL MOUSE MODEL OF OBESITY PARADOX. Virtue A, etal., J Biol Chem. 2017 Jan 27;292(4):1267-1287. doi: 10.1074/jbc.M116.739839. Epub 2016 Nov 17.
76. MiRNA-155 Regulates the Th17/Treg Ratio by Targeting SOCS1 in Severe Acute Pancreatitis. Wang D, etal., Front Physiol. 2018 Jun 8;9:686. doi: 10.3389/fphys.2018.00686. eCollection 2018.
77. Decreased MiR-155 Level in the Peripheral Blood of Non-Alcoholic Fatty Liver Disease Patients may Serve as a Biomarker and may Influence LXR Activity. Wang L, etal., Cell Physiol Biochem. 2016;39(6):2239-2248. doi: 10.1159/000447917. Epub 2016 Nov 7.
78. MicroRNA Microarray-Based Identification of Involvement of miR-155 and miR-19a in Development of Oral Lichen Planus (OLP) by Modulating Th1/Th2 Balance via Targeting eNOS and Toll-Like Receptor 2 (TLR2). Wang L, etal., Med Sci Monit. 2018 May 29;24:3591-3603. doi: 10.12659/MSM.907497.
79. MicroRNA-155 inversely correlates with esophageal cancer progression through regulating tumor-associated macrophage FGF2 expression. Wang P, etal., Biochem Biophys Res Commun. 2018 Sep 5;503(2):452-458. doi: 10.1016/j.bbrc.2018.04.094. Epub 2018 Jun 30.
80. Macrophage micro-RNA-155 promotes lipopolysaccharide-induced acute lung injury in mice and rats. Wang W, etal., Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L494-506. doi: 10.1152/ajplung.00001.2016. Epub 2016 Jul 1.
81. HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines. Wang W, etal., Cell Mol Life Sci. 2018 Jul;75(14):2627-2641. doi: 10.1007/s00018-018-2753-8. Epub 2018 Jan 18.
82. Involvement of the Negative Feedback of IL-33 Signaling in the Anti-Inflammatory Effect of Electro-acupuncture on Allergic Contact Dermatitis via Targeting MicroRNA-155 in Mast Cells. Wang Z, etal., Inflammation. 2018 Jun;41(3):859-869. doi: 10.1007/s10753-018-0740-8.
83. Inhibition of microRNA-155 attenuates concanavalin-A-induced autoimmune hepatitis by regulating Treg/Th17 cell differentiation. Xia G, etal., Can J Physiol Pharmacol. 2018 Dec;96(12):1293-1300. doi: 10.1139/cjpp-2018-0467. Epub 2018 Oct 5.
84. MiR-155 contributes to Th17 cells differentiation in dextran sulfate sodium (DSS)-induced colitis mice via Jarid2. Xu M, etal., Biochem Biophys Res Commun. 2017 Jun 17;488(1):6-14. doi: 10.1016/j.bbrc.2017.04.143. Epub 2017 Apr 28.
85. [Circulating Serum MicroRNA as Diagnostic Biomarkers for Multiple Myeloma]. Xu YN, etal., Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Apr;25(2):471-475. doi: 10.7534/j.issn.1009-2137.2017.02.029.
86. Tanshinone IIA Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice Infected with Porphyromonas gingivalis. Xuan Y, etal., Inflammation. 2017 Oct;40(5):1631-1642. doi: 10.1007/s10753-017-0603-8.
87. Repression of lncRNA NEAT1 enhances the antitumor activity of CD8+T cells against hepatocellular carcinoma via regulating miR-155/Tim-3. Yan K, etal., Int J Biochem Cell Biol. 2019 May;110:1-8. doi: 10.1016/j.biocel.2019.01.019. Epub 2019 Jan 30.
88. The inhibitory effect of Gualou Guizhi Decoction on post-ischemic neuroinflammation via miR-155 in MCAO rats. Yang J, etal., Ann Palliat Med. 2021 Feb;10(2):1370-1379. doi: 10.21037/apm-20-518. Epub 2020 Oct 16.
89. Visualizing the Conversion Process of Alcohol-Induced Fatty Liver to Steatohepatitis in Vivo with a Fluorescent Nanoprobe. Yang L, etal., Anal Chem. 2017 Jun 6;89(11):6196-6201. doi: 10.1021/acs.analchem.7b01144. Epub 2017 May 17.
90. MiR-155 aggravated septic liver injury by oxidative stress-mediated ER stress and mitochondrial dysfunction via targeting Nrf-2. Yang ZB, etal., Exp Mol Pathol. 2018 Dec;105(3):387-394. doi: 10.1016/j.yexmp.2018.09.003. Epub 2018 Sep 13.
91. [Expression of microRNA-155 in inflammatory bowel disease and its clinical significance]. Ye YL, etal., Zhonghua Yi Xue Za Zhi. 2017 Dec 19;97(47):3716-3719. doi: 10.3760/cma.j.issn.0376-2491.2017.47.007.
92. Association of MicroRNA-210 and MicroRNA-155 with severity of preeclampsia. Youssef HMG and Marei ES, Pregnancy Hypertens. 2019 Jul;17:49-53. doi: 10.1016/j.preghy.2019.05.010. Epub 2019 May 10.
93. Fine-tuning the expression of microRNA-155 controls acetaminophen-induced liver inflammation. Yuan K, etal., Int Immunopharmacol. 2016 Nov;40:339-346. doi: 10.1016/j.intimp.2016.09.011. Epub 2016 Sep 24.
94. Expression of miRNA-146a, miRNA-155, IL-2, and TNF-α in inflammatory response to Helicobacter pylori infection associated with cancer progression. Zabaglia LM, etal., Ann Hum Genet. 2018 May;82(3):135-142. doi: 10.1111/ahg.12234. Epub 2017 Dec 18.
95. Decreased miR-155-5p, miR-15a, and miR-186 Expression in Gastric Cancer Is Associated with Advanced Tumor Grade and Metastasis Zare A, etal., Iran Biomed J. 2019 Sep;23(5):338-343. Epub 2019 May 19.
96. A Feedback Loop between MicroRNA 155 (miR-155), Programmed Cell Death 4, and Activation Protein 1 Modulates the Expression of miR-155 and Tumorigenesis in Tongue Cancer. Zargar S, etal., Mol Cell Biol. 2019 Mar 1;39(6). pii: MCB.00410-18. doi: 10.1128/MCB.00410-18. Print 2019 Mar 15.
97. DNA Tetrahedral Nanostructure-Based Electrochemical miRNA Biosensor for Simultaneous Detection of Multiple miRNAs in Pancreatic Carcinoma. Zeng D, etal., ACS Appl Mater Interfaces. 2017 Jul 19;9(28):24118-24125. doi: 10.1021/acsami.7b05981. Epub 2017 Jul 5.
98. Investigating the microRNA-mRNA regulatory network in acute myeloid leukemia. Zhang H, etal., Oncol Lett. 2017 Oct;14(4):3981-3988. doi: 10.3892/ol.2017.6686. Epub 2017 Jul 28.
99. Acupuncture Decreases NF-κB p65, miR-155, and miR-21 and Increases miR-146a Expression in Chronic Atrophic Gastritis Rats. Zhang J, etal., Evid Based Complement Alternat Med. 2016;2016:9404629. doi: 10.1155/2016/9404629. Epub 2016 May 18.
100. MicroRNA-155 promotes tumor growth of human hepatocellular carcinoma by targeting ARID2. Zhang L, etal., Int J Oncol. 2016 Jun;48(6):2425-34. doi: 10.3892/ijo.2016.3465. Epub 2016 Mar 30.
101. Role of miR-155 in the regulation of MMP-16 expression in intervertebral disc degeneration. Zhang WL, etal., J Orthop Res. 2017 Jun;35(6):1323-1334. doi: 10.1002/jor.23313. Epub 2017 Apr 24.
102. MicroRNA-155 expression as a prognostic factor in patients with gallbladder carcinoma after surgical resection. Zhang XL, etal., Int J Clin Exp Med. 2015 Nov 15;8(11):21241-6. eCollection 2015.
103. Activation of PD-1 Protects Intestinal Immune Defense Through IL-10/miR-155 Pathway After Intestinal Ischemia Reperfusion. Zhang XY, etal., Dig Dis Sci. 2018 Dec;63(12):3307-3316. doi: 10.1007/s10620-018-5282-2. Epub 2018 Sep 12.
104. MicroRNA-155 modulates bile duct inflammation by targeting the suppressor of cytokine signaling 1 in biliary atresia. Zhao R, etal., Pediatr Res. 2017 Dec;82(6):1007-1016. doi: 10.1038/pr.2017.87. Epub 2017 Sep 6.
105. Inflammation-Related MicroRNAs Are Associated with Plaque Stability Calculated by IVUS in Coronary Heart Disease Patients. Zhu GF, etal., J Interv Cardiol. 2019 Dec 1;2019:9723129. doi: 10.1155/2019/9723129. eCollection 2019.
106. Hyperlipidemia-Induced MicroRNA-155-5p Improves β-Cell Function by Targeting Mafb. Zhu M, etal., Diabetes. 2017 Dec;66(12):3072-3084. doi: 10.2337/db17-0313. Epub 2017 Sep 29.
Additional References at PubMed
PMID:12007417   PMID:14695998   PMID:15325244   PMID:15634332   PMID:15738415   PMID:16041695   PMID:16252262   PMID:16381832   PMID:17604727   PMID:17616659   PMID:17668390   PMID:17989717  
PMID:18048365   PMID:18055230   PMID:18191785   PMID:18354490   PMID:18383392   PMID:18753206   PMID:18759964   PMID:18926796   PMID:18940871   PMID:19106647   PMID:19136465   PMID:19193853  
PMID:19234151   PMID:19268705   PMID:19289845   PMID:19386588   PMID:19446359   PMID:19538740   PMID:19551852   PMID:19578755   PMID:19641183   PMID:19701459   PMID:19777054   PMID:19887047  
PMID:19890474   PMID:19954362   PMID:20041145   PMID:20133617   PMID:20201617   PMID:20209161   PMID:20219467   PMID:20332664   PMID:20351277   PMID:20370992   PMID:20388420   PMID:20427544  
PMID:20452491   PMID:20550618   PMID:20673989   PMID:20844043   PMID:20889907   PMID:20947507   PMID:20950585   PMID:20952466   PMID:20966899   PMID:21030878   PMID:21036908   PMID:21037258  
PMID:21097505   PMID:21176560   PMID:21195055   PMID:21219656   PMID:21234519   PMID:21282106   PMID:21296997   PMID:21304824   PMID:21310411   PMID:21355095   PMID:21383199   PMID:21385848  
PMID:21412018   PMID:21466664   PMID:21515911   PMID:21541331   PMID:21690378   PMID:21703910   PMID:21706480   PMID:21750860   PMID:21756067   PMID:21762537   PMID:21762626   PMID:21802214  
PMID:21806946   PMID:21807897   PMID:21813606   PMID:21831295   PMID:21863027   PMID:21982894   PMID:21987229   PMID:21989846   PMID:22006119   PMID:22037148   PMID:22048267   PMID:22071603  
PMID:22096245   PMID:22105810   PMID:22113482   PMID:22122052   PMID:22139425   PMID:22139839   PMID:22182977   PMID:22245916   PMID:22249254   PMID:22268450   PMID:22272099   PMID:22307849  
PMID:22348515   PMID:22350414   PMID:22354042   PMID:22378844   PMID:22387553   PMID:22426647   PMID:22445295   PMID:22470130   PMID:22508041   PMID:22511990   PMID:22541087   PMID:22558995  
PMID:22562822   PMID:22578600   PMID:22609116   PMID:22652783   PMID:22681934   PMID:22715471   PMID:22728346   PMID:22736789   PMID:22797073   PMID:22815348   PMID:22823535   PMID:22891887  
PMID:22919664   PMID:22924844   PMID:22942255   PMID:22957494   PMID:22982040   PMID:22996741   PMID:23028330   PMID:23047434   PMID:23050614   PMID:23065188   PMID:23071695   PMID:23108656  
PMID:23166327   PMID:23166356   PMID:23174997   PMID:23185331   PMID:23209550   PMID:23246696   PMID:23250986   PMID:23264052   PMID:23288924   PMID:23302469   PMID:23312020   PMID:23316018  
PMID:23334650   PMID:23353819   PMID:23428672   PMID:23437123   PMID:23454155   PMID:23462458   PMID:23509825   PMID:23523916   PMID:23524258   PMID:23568502   PMID:23580661   PMID:23588589  
PMID:23601686   PMID:23616185   PMID:23616573   PMID:23650424   PMID:23660842   PMID:23661430   PMID:23676217   PMID:23693020   PMID:23711069   PMID:23750211   PMID:23774697   PMID:23796566  
PMID:23817566   PMID:23818336   PMID:23821659   PMID:23827206   PMID:23949802   PMID:23955085   PMID:23967196   PMID:23970205   PMID:24007214   PMID:24033365   PMID:24037889   PMID:24059932  
PMID:24080728   PMID:24120842   PMID:24151514   PMID:24152184   PMID:24177167   PMID:24227772   PMID:24241359   PMID:24252850   PMID:24262949   PMID:24283299   PMID:24311783   PMID:24332164  
PMID:24362029   PMID:24376632   PMID:24387321   PMID:24391808   PMID:24403198   PMID:24403554   PMID:24447044   PMID:24460255   PMID:24494749   PMID:24519663   PMID:24522920   PMID:24525789  
PMID:24551280   PMID:24554510   PMID:24562503   PMID:24571026   PMID:24583476   PMID:24591085   PMID:24604078   PMID:24616504   PMID:24623016   PMID:24657879   PMID:24692283   PMID:24708856  
PMID:24743332   PMID:24789113   PMID:24793496   PMID:24804980   PMID:24805774   PMID:24806148   PMID:24824925   PMID:24840899   PMID:24854560   PMID:24856900   PMID:24876105   PMID:24877885  
PMID:24885259   PMID:24888652   PMID:24905663   PMID:24909288   PMID:24910152   PMID:24914134   PMID:24930753   PMID:24960647   PMID:24963214   PMID:24969405   PMID:25092123   PMID:25092144  
PMID:25128227   PMID:25142507   PMID:25143000   PMID:25155037   PMID:25157366   PMID:25175984   PMID:25180620   PMID:25182190   PMID:25185784   PMID:25197634   PMID:25211095   PMID:25219837  
PMID:25253569   PMID:25261908   PMID:25265435   PMID:25283550   PMID:25295729   PMID:25315114   PMID:25339368   PMID:25355421   PMID:25401928   PMID:25413124   PMID:25420938   PMID:25456009  
PMID:25480585   PMID:25484137   PMID:25486872   PMID:25503185   PMID:25522282   PMID:25528214   PMID:25535908   PMID:25601564   PMID:25614225   PMID:25630602   PMID:25633840   PMID:25666090  
PMID:25672593   PMID:25672607   PMID:25720442   PMID:25730818   PMID:25740880   PMID:25753878   PMID:25760478   PMID:25761610   PMID:25772938   PMID:25820993   PMID:25823817   PMID:25829072  
PMID:25850724   PMID:25853464   PMID:25869329   PMID:25872580   PMID:25873391   PMID:25888631   PMID:25910754   PMID:25916938   PMID:25918190   PMID:25929465   PMID:25953724   PMID:25965824  
PMID:25971362   PMID:25972604   PMID:25998827   PMID:26012521   PMID:26020803   PMID:26055806   PMID:26055960   PMID:26056431   PMID:26064968   PMID:26068396   PMID:26072128   PMID:26156524  
PMID:26159489   PMID:26176991   PMID:26188366   PMID:26191144   PMID:26195069   PMID:26211004   PMID:26223652   PMID:26261072   PMID:26261588   PMID:26307116   PMID:26317550   PMID:26324048  
PMID:26337206   PMID:26339601   PMID:26425555   PMID:26433115   PMID:26497687   PMID:26539029   PMID:26543233   PMID:26548866   PMID:26589288   PMID:26589478   PMID:26594049   PMID:26620207  
PMID:26621153   PMID:26624800   PMID:26646931   PMID:26657502   PMID:26752469   PMID:26779627   PMID:26795347   PMID:26823719   PMID:26829440   PMID:26831604   PMID:26841929   PMID:26842862  
PMID:26850462   PMID:26855180   PMID:26889816   PMID:26899994   PMID:26911687   PMID:26921773   PMID:26931072   PMID:26934326   PMID:26935979   PMID:26955820   PMID:26967247   PMID:26986233  
PMID:27009385   PMID:27014996   PMID:27016615   PMID:27028953   PMID:27041566   PMID:27064870   PMID:27065318   PMID:27079198   PMID:27086919   PMID:27110708   PMID:27113301   PMID:27160903  
PMID:27185878   PMID:27246008   PMID:27246706   PMID:27284727   PMID:27294145   PMID:27296000   PMID:27306418   PMID:27310932   PMID:27315591   PMID:27320691   PMID:27377409   PMID:27411480  
PMID:27412942   PMID:27420617   PMID:27462776   PMID:27470551   PMID:27473081   PMID:27497617   PMID:27530922   PMID:27534887   PMID:27535005   PMID:27565163   PMID:27601730   PMID:27602769  
PMID:27619068   PMID:27635110   PMID:27643599   PMID:27646435   PMID:27671860   PMID:27692344   PMID:27706699   PMID:27717891   PMID:27731397   PMID:27740637   PMID:27746237   PMID:27751368  
PMID:27761889   PMID:27783037   PMID:27786352   PMID:27796698   PMID:27811366   PMID:27872469   PMID:27880937   PMID:27885839   PMID:27903673   PMID:27981414   PMID:28006785   PMID:28018919  
PMID:28031239   PMID:28087411   PMID:28118944   PMID:28130497   PMID:28132399   PMID:28140712   PMID:28146070   PMID:28146427   PMID:28148469   PMID:28164567   PMID:28214207   PMID:28240738  
PMID:28247149   PMID:28251496   PMID:28259135   PMID:28281962   PMID:28301819   PMID:28316102   PMID:28371892   PMID:28402921   PMID:28407320   PMID:28407516   PMID:28423578   PMID:28423722  
PMID:28431233   PMID:28468592   PMID:28471953   PMID:28562349   PMID:28569050   PMID:28593612   PMID:28607031   PMID:28612526   PMID:28618412   PMID:28623945   PMID:28627655   PMID:28628920  
PMID:28642130   PMID:28647559   PMID:28662100   PMID:28664228   PMID:28664667   PMID:28683581   PMID:28685309   PMID:28688901   PMID:28720071   PMID:28727276   PMID:28731457   PMID:28748483  
PMID:28782994   PMID:28790455   PMID:28842954   PMID:28870579   PMID:28880456   PMID:28885613   PMID:28910312   PMID:28939896   PMID:28962081   PMID:28967703   PMID:28994735   PMID:29017169  
PMID:29066622   PMID:29103027   PMID:29115566   PMID:29146158   PMID:29191771   PMID:29240254   PMID:29247570   PMID:29249119   PMID:29281614   PMID:29300789   PMID:29328396   PMID:29333944  
PMID:29339071   PMID:29364476   PMID:29385860   PMID:29411649   PMID:29463948   PMID:29467762   PMID:29471005   PMID:29517281   PMID:29545091   PMID:29550489   PMID:29582620   PMID:29601851  
PMID:29620202   PMID:29627439   PMID:29654787   PMID:29658868   PMID:29661714   PMID:29693176   PMID:29751003   PMID:29752719   PMID:29767259   PMID:29785488   PMID:29790117   PMID:29803178  
PMID:29807272   PMID:29848325   PMID:29863307   PMID:29885519   PMID:29901087   PMID:29901097   PMID:29936517   PMID:29945912   PMID:29949145   PMID:29981742   PMID:29991021   PMID:30006293  
PMID:30015881   PMID:30031401   PMID:30032344   PMID:30046360   PMID:30049532   PMID:30091834   PMID:30125933   PMID:30171379   PMID:30201497   PMID:30209639   PMID:30297336   PMID:30299211  
PMID:30302809   PMID:30335891   PMID:30362157   PMID:30365045   PMID:30398001   PMID:30399324   PMID:30401711   PMID:30414370   PMID:30430204   PMID:30458743   PMID:30465177   PMID:30468477  
PMID:30478850   PMID:30482883   PMID:30485839   PMID:30515165   PMID:30536304   PMID:30554090   PMID:30621915   PMID:30670568   PMID:30692098   PMID:30721153   PMID:30734973   PMID:30820789  
PMID:30825229   PMID:30837408   PMID:30839051   PMID:30878390   PMID:30898623   PMID:30915770   PMID:30925928   PMID:30928987   PMID:30950329   PMID:30962309   PMID:30968694   PMID:30998152  
PMID:30998423   PMID:31009294   PMID:31016751   PMID:31036495   PMID:31081043   PMID:31090940   PMID:31162747   PMID:31173279   PMID:31252530   PMID:31282135   PMID:31338876   PMID:31355605  
PMID:31364113   PMID:31404910   PMID:31414764   PMID:31424663   PMID:31469179   PMID:31481696   PMID:31484730   PMID:31485611   PMID:31485649   PMID:31502418   PMID:31505404   PMID:31531958  
PMID:31570669   PMID:31599418   PMID:31601967   PMID:31603116   PMID:31628193   PMID:31657855   PMID:31669646   PMID:31696995   PMID:31709859   PMID:31718618   PMID:31721599   PMID:31726271  
PMID:31727002   PMID:31744065   PMID:31752013   PMID:31770330   PMID:31773704   PMID:31801218   PMID:31810510   PMID:31819170   PMID:31833346   PMID:31849465   PMID:31851829   PMID:31852252  
PMID:31856677   PMID:31872268   PMID:31880114   PMID:31907159   PMID:31907997   PMID:31910343   PMID:31918270   PMID:31930529   PMID:31942966   PMID:31945413   PMID:31945658   PMID:31948758  
PMID:31959117   PMID:31986951   PMID:32027250   PMID:32051698   PMID:32090104   PMID:32096299   PMID:32102529   PMID:32124227   PMID:32151564   PMID:32196916   PMID:32215174   PMID:32220051  
PMID:32227733   PMID:32237066   PMID:32243922   PMID:32248286   PMID:32289665   PMID:32323747   PMID:32323857   PMID:32331943   PMID:32359033   PMID:32372074   PMID:32415722   PMID:32417393  
PMID:32432745   PMID:32460356   PMID:32472715   PMID:32484820   PMID:32485219   PMID:32527448   PMID:32556361   PMID:32562373   PMID:32573268   PMID:32579760   PMID:32580736   PMID:32587662  
PMID:32602388   PMID:32614381   PMID:32623835   PMID:32634427   PMID:32666270   PMID:32696744   PMID:32702393   PMID:32707293   PMID:32720541   PMID:32725652   PMID:32757734   PMID:32770080  
PMID:32798423   PMID:32823863   PMID:32853020   PMID:32868076   PMID:32889908   PMID:32902755   PMID:32908449   PMID:32938348   PMID:32941675   PMID:32946865   PMID:32991030   PMID:33000196  
PMID:33006449   PMID:33068176   PMID:33081305   PMID:33090390   PMID:33099657   PMID:33121529   PMID:33125052   PMID:33134385   PMID:33148068   PMID:33174061   PMID:33179091   PMID:33221530  
PMID:33268675   PMID:33283723   PMID:33287921   PMID:33294082   PMID:33317369   PMID:33357126   PMID:33391256   PMID:33480329   PMID:33481955   PMID:33486545   PMID:33494773   PMID:33500248  
PMID:33506901   PMID:33540559   PMID:33622174   PMID:33629312   PMID:33636223   PMID:33714739   PMID:33719773   PMID:33760254   PMID:33769664   PMID:33790910   PMID:33800594   PMID:33827350  
PMID:33830643   PMID:33835399   PMID:33841404   PMID:33862068   PMID:33862181   PMID:33888045   PMID:33895969   PMID:33919306   PMID:33957967   PMID:33993032   PMID:33999777   PMID:34022359  
PMID:34024195   PMID:34105469   PMID:34155822   PMID:34171684   PMID:34180348   PMID:34192708   PMID:34221208   PMID:34274194   PMID:34294459   PMID:34348591   PMID:34382731   PMID:34399118  
PMID:34437653   PMID:34449559   PMID:34470679   PMID:34479599   PMID:34482266   PMID:34482798   PMID:34611142   PMID:34626873   PMID:34698413   PMID:34731784   PMID:34753061   PMID:34775495  
PMID:34815425   PMID:34821091   PMID:34824176   PMID:34831066   PMID:34835072   PMID:34838331   PMID:34850769   PMID:34865098   PMID:34905088   PMID:34913612   PMID:34921979   PMID:34950438  
PMID:34981333   PMID:34983581   PMID:35015112   PMID:35020867   PMID:35064409   PMID:35078194   PMID:35098407   PMID:35132337   PMID:35157721   PMID:35164998   PMID:35196550   PMID:35253975  
PMID:35264708   PMID:35277868   PMID:35395973   PMID:35395974   PMID:35411714   PMID:35412895   PMID:35434143   PMID:35500644   PMID:35511436   PMID:35524373   PMID:35534864   PMID:35545774  
PMID:35563301   PMID:35611851   PMID:35707883   PMID:35733067   PMID:35777901   PMID:35809285   PMID:35845734   PMID:35885930   PMID:35925680   PMID:35928925   PMID:35949047   PMID:35986010  
PMID:35993471   PMID:35999071   PMID:36139455   PMID:36142173   PMID:36153499   PMID:36155522   PMID:36206922   PMID:36308539   PMID:36329419   PMID:36499743   PMID:36613718   PMID:36623778  
PMID:36688191   PMID:36693551   PMID:36696711   PMID:36750001   PMID:36753984   PMID:36766808   PMID:36916095   PMID:36923408   PMID:36939982   PMID:37070646   PMID:37142295   PMID:37175531  
PMID:37197667   PMID:37307689   PMID:37327858   PMID:37639012   PMID:37661808   PMID:37720228   PMID:37843075   PMID:37914735   PMID:37925110   PMID:37942654   PMID:37945677   PMID:37953568  
PMID:37974134   PMID:38005883   PMID:38050671   PMID:38063105   PMID:38221897   PMID:38325118   PMID:38396844   PMID:38400867   PMID:38508350  


Genomics

Comparative Map Data
MIR155
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382125,573,980 - 25,574,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2125,573,980 - 25,574,044 (+)EnsemblGRCh38hg38GRCh38
GRCh372126,946,292 - 26,946,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera2112,129,700 - 12,129,764 (+)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2112,349,435 - 12,349,499 (+)NCBIHuRef
CHM1_12126,506,960 - 26,507,024 (+)NCBICHM1_1
T2T-CHM13v2.02123,931,556 - 23,931,620 (+)NCBIT2T-CHM13v2.0
Mir155
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391684,511,028 - 84,511,092 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1684,511,028 - 84,511,092 (+)EnsemblGRCm39 Ensembl
GRCm381684,714,140 - 84,714,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1684,714,140 - 84,714,204 (+)EnsemblGRCm38mm10GRCm38
MGSCv371684,714,385 - 84,714,449 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1684,918,138 - 84,918,202 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1646.92NCBI
Mir155
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,261,114 - 37,261,178 (+)NCBIGRCr8
mRatBN7.21123,774,654 - 23,774,718 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1123,774,654 - 23,774,718 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1132,481,023 - 32,481,087 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01125,181,422 - 25,181,486 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01124,370,128 - 24,370,192 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01124,176,603 - 24,176,667 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,176,603 - 24,176,667 (+)EnsemblRnor6.0rn6Rnor6.0
Celera1123,614,233 - 23,614,297 (+)NCBICelera
Cytogenetic Map11q11NCBI
MIR155
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13121,078,768 - 21,078,828 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3121,078,758 - 21,078,833 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3121,138,038 - 21,138,098 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03121,132,843 - 21,132,903 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13121,151,558 - 21,151,618 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03121,152,631 - 21,152,691 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03121,627,607 - 21,627,667 (+)NCBIUU_Cfam_GSD_1.0
MIR155
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13189,138,822 - 189,138,902 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113189,138,822 - 189,138,902 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213199,063,344 - 199,063,424 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000050445] Chr21:7749532..46670405 [GRCh38]
Chr21:15499847..48090317 [GRCh37]
Chr21:14421718..46914745 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic|conflicting interpretations of pathogenicity|conflicting data from submitters
GRCh38/hg38 21q11.2-21.3(chr21:13194345-29257208)x1 copy number loss See cases [RCV000052798] Chr21:13194345..29257208 [GRCh38]
Chr21:14566666..30629529 [GRCh37]
Chr21:13488537..29551400 [NCBI36]
Chr21:21q11.2-21.3		 pathogenic
GRCh38/hg38 21q11.2-22.11(chr21:14000720-30903065)x1 copy number loss See cases [RCV000052799] Chr21:14000720..30903065 [GRCh38]
Chr21:15373041..32275384 [GRCh37]
Chr21:14294912..31197255 [NCBI36]
Chr21:21q11.2-22.11		 pathogenic
GRCh38/hg38 21q21.2-21.3(chr21:24292832-27046585)x1 copy number loss See cases [RCV000052804] Chr21:24292832..27046585 [GRCh38]
Chr21:25665145..28418904 [GRCh37]
Chr21:24587016..27340775 [NCBI36]
Chr21:21q21.2-21.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46653090)x3 copy number gain See cases [RCV000053040] Chr21:7749532..46653090 [GRCh38]
Chr21:14539679..48073002 [GRCh37]
Chr21:13461550..46897430 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053042] Chr21:7749532..46623792 [GRCh38]
Chr21:14595524..48043704 [GRCh37]
Chr21:13517395..46868132 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053043] Chr21:7749532..46623792 [GRCh38]
Chr21:14629063..48043704 [GRCh37]
Chr21:13550934..46868132 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670546)x3 copy number gain See cases [RCV000053045] Chr21:7749532..46670546 [GRCh38]
Chr21:15499647..48090458 [GRCh37]
Chr21:14421518..46914886 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46661140)x3 copy number gain See cases [RCV000053065] Chr21:7749532..46661140 [GRCh38]
Chr21:15499647..48081052 [GRCh37]
Chr21:14421518..46905480 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46661140)x3 copy number gain See cases [RCV000053067] Chr21:7749532..46661140 [GRCh38]
Chr21:15499847..48081052 [GRCh37]
Chr21:14421718..46905480 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000053068] Chr21:7749532..46670405 [GRCh38]
Chr21:20655360..48090317 [GRCh37]
Chr21:19577231..46914745 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46623792)x3 copy number gain See cases [RCV000053039] Chr21:7749532..46623792 [GRCh38]
Chr21:14524963..48043704 [GRCh37]
Chr21:13446834..46868132 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q22.11-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000135310] Chr21:7749532..46670346 [GRCh38]
Chr21:34111831..48090258 [GRCh37]
Chr21:33033702..46914686 [NCBI36]
Chr21:21q22.11-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-42971047)x3 copy number gain See cases [RCV000133676] Chr21:7749532..42971047 [GRCh38]
Chr21:15499847..44391157 [GRCh37]
Chr21:14421718..43264226 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46653084)x3 copy number gain See cases [RCV000134727] Chr21:7749532..46653084 [GRCh38]
Chr21:15485038..48072996 [GRCh37]
Chr21:14406909..46897424 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46649831)x3 copy number gain See cases [RCV000134509] Chr21:7749532..46649831 [GRCh38]
Chr21:14577835..48069743 [GRCh37]
Chr21:13499706..46894171 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670440)x3 copy number gain See cases [RCV000134119] Chr21:7749532..46670440 [GRCh38]
Chr21:15485038..48090352 [GRCh37]
Chr21:14406909..46914780 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46664250)x3 copy number gain See cases [RCV000134836] Chr21:7749532..46664250 [GRCh38]
Chr21:15485038..48084162 [GRCh37]
Chr21:14406909..46908590 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670440)x3 copy number gain See cases [RCV000134842] Chr21:7749532..46670440 [GRCh38]
Chr21:15513244..48090352 [GRCh37]
Chr21:14435115..46914780 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46660999)x3 copy number gain See cases [RCV000135448] Chr21:7749532..46660999 [GRCh38]
Chr21:15499847..48080911 [GRCh37]
Chr21:14421718..46905339 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000137255] Chr21:7749532..46671060 [GRCh38]
Chr21:35319225..48090972 [GRCh37]
Chr21:34241095..46915400 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000137337] Chr21:7749532..46671060 [GRCh38]
Chr21:10697897..48090972 [GRCh37]
Chr21:1..46915400 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.13(chr21:7749532-37653653)x1 copy number loss See cases [RCV000138095] Chr21:7749532..37653653 [GRCh38]
Chr21:15451032..39025955 [GRCh37]
Chr21:14372903..37947825 [NCBI36]
Chr21:21p11.2-q22.13		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000138216] Chr21:7749532..46671060 [GRCh38]
Chr21:10944001..48090972 [GRCh37]
Chr21:9965872..46915400 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46671060)x3 copy number gain See cases [RCV000138436] Chr21:7749532..46671060 [GRCh38]
Chr21:15451032..48090972 [GRCh37]
Chr21:14372903..46915400 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic|conflicting data from submitters
GRCh38/hg38 21q21.1-21.3(chr21:22270514-27695129)x1 copy number loss See cases [RCV000138937] Chr21:22270514..27695129 [GRCh38]
Chr21:23642834..29067448 [GRCh37]
Chr21:22564705..27989319 [NCBI36]
Chr21:21q21.1-21.3		 likely pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46670346)x3 copy number gain See cases [RCV000140103] Chr21:7749532..46670346 [GRCh38]
Chr21:14577894..48090258 [GRCh37]
Chr21:13499765..46914686 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46698247)x3 copy number gain See cases [RCV000141346] Chr21:7749532..46698247 [GRCh38]
Chr21:14577835..48118159 [GRCh37]
Chr21:13499706..46942587 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7817158-46670440)x1 copy number loss See cases [RCV000142427] Chr21:7817158..46670440 [GRCh38]
Chr21:15485038..48090352 [GRCh37]
Chr21:14406909..46914780 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q21.1-22.11(chr21:19423169-31841150)x1 copy number loss See cases [RCV000142217] Chr21:19423169..31841150 [GRCh38]
Chr21:20795486..33213462 [GRCh37]
Chr21:19717357..32135333 [NCBI36]
Chr21:21q21.1-22.11		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000143376] Chr21:7749532..46677460 [GRCh38]
Chr21:15006458..48097372 [GRCh37]
Chr21:13928329..46921800 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460) copy number gain See cases [RCV000143160] Chr21:7749532..46677460 [GRCh38]
Chr21:14386013..48097372 [GRCh37]
Chr21:13307884..46921800 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21q11.2-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000143120] Chr21:7749532..46677460 [GRCh38]
Chr21:15006457..48097372 [GRCh37]
Chr21:13928328..46921800 [NCBI36]
Chr21:21q11.2-22.3		 pathogenic
GRCh38/hg38 21q11.2-21.3(chr21:13634137-27862841)x1 copy number loss See cases [RCV000143749] Chr21:13634137..27862841 [GRCh38]
Chr21:15006458..29235160 [GRCh37]
Chr21:13928329..28157031 [NCBI36]
Chr21:21q11.2-21.3		 pathogenic
NC_000021.7:g.13636378_28138533dup duplication Alzheimer disease [RCV000148341] Chr21:14714507..29216662 [GRCh37]
Chr21:13636378..28138533 [NCBI36]
Chr21:21q11.2-21.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000148131] Chr21:7749532..46670405 [GRCh38]
Chr21:15499847..48090317 [GRCh37]
Chr21:14421718..46914745 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21p11.2-q22.3(chr21:7749532-46670405)x3 copy number gain See cases [RCV000053069] Chr21:7749532..46670405 [GRCh38]
Chr21:34423268..48090317 [GRCh37]
Chr21:33345138..46914745 [NCBI36]
Chr21:21p11.2-q22.3		 pathogenic
GRCh38/hg38 21q21.3-22.3(chr21:7749532-46677460)x3 copy number gain See cases [RCV000141827] Chr21:7749532..46677460 [GRCh38]
Chr21:28285299..48097372 [GRCh37]
Chr21:27207170..46921800 [NCBI36]
Chr21:21q21.3-22.3		 uncertain significance
GRCh38/hg38 21q11.2-21.3(chr21:14000146-27785985) copy number loss Monosomy 21 [RCV000225561] Chr21:14000146..27785985 [GRCh38]
Chr21:21q11.2-21.3		 pathogenic
GRCh38/hg38 21p11.2-q21.3(chr21:13048294-27532614) copy number loss Monosomy 21 [RCV000225452] Chr21:13048294..27532614 [GRCh38]
Chr21:21p11.2-q21.3		 pathogenic
GRCh38/hg38 21q21.1-22.11(chr21:21754822-32380347) copy number loss Monosomy 21 [RCV000225665] Chr21:21754822..32380347 [GRCh38]
Chr21:21q21.1-22.11		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15538655-48080926)x1 copy number loss See cases [RCV000239948] Chr21:15538655..48080926 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15410701-48090317)x3 copy number gain See cases [RCV000240397] Chr21:15410701..48090317 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-43598570)x3 copy number gain See cases [RCV000446716] Chr21:15006457..43598570 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:14771770-48080867)x3 copy number gain See cases [RCV000447884] Chr21:14771770..48080867 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-44827632)x3 copy number gain See cases [RCV000448199] Chr21:15006457..44827632 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15285841-48097372)x3 copy number gain See cases [RCV000447729] Chr21:15285841..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain See cases [RCV000447749] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-21.3(chr21:15006457-29225300)x1 copy number loss See cases [RCV000510539] Chr21:15006457..29225300 [GRCh37]
Chr21:21q11.2-21.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006458-48097372) copy number gain See cases [RCV000511589] Chr21:15006458..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10827533-48100155)x3 copy number gain not provided [RCV000741419] Chr21:10827533..48100155 [GRCh37]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10699330-48117896)x3 copy number gain not provided [RCV000741413] Chr21:10699330..48117896 [GRCh37]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10704198-48117896)x3 copy number gain not provided [RCV000741415] Chr21:10704198..48117896 [GRCh37]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21p11.2-q22.3(chr21:10824040-48090629)x3 copy number gain not provided [RCV000741418] Chr21:10824040..48090629 [GRCh37]
Chr21:21p11.2-q22.3		 pathogenic
GRCh37/hg19 21q11.2-21.3(chr21:15006457-29325923)x1 copy number loss not provided [RCV001007109] Chr21:15006457..29325923 [GRCh37]
Chr21:21q11.2-21.3		 pathogenic
Single allele duplication Neurodevelopmental disorder [RCV000787411] Chr21:14374186..29305180 [GRCh37]
Chr21:21q11.2-21.3		 likely pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain not provided [RCV000846937] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q21.3(chr21:26908459-27358327)x3 copy number gain not provided [RCV000848217] Chr21:26908459..27358327 [GRCh37]
Chr21:21q21.3		 uncertain significance
GRCh37/hg19 21q11.2-22.3(chr21:14629063-48090317)x3 copy number gain See cases [RCV001263025] Chr21:14629063..48090317 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:14420615-48080926)x3 copy number gain Complete trisomy 21 syndrome [RCV002284306] Chr21:14420615..48080926 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21p13-q22.3(chr21:1-48129895)x3 copy number gain See cases [RCV001780078] Chr21:1..48129895 [GRCh37]
Chr21:21p13-q22.3		 pathogenic
Single allele duplication Alzheimer disease [RCV001810749] Chr21:26253828..30011000 [GRCh37]
Chr21:21q21.2-21.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15041209-48097372) copy number gain not specified [RCV002052724] Chr21:15041209..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-21.3(chr21:15006457-27430623) copy number gain not specified [RCV002052721] Chr21:15006457..27430623 [GRCh37]
Chr21:21q11.2-21.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15285841-48097372) copy number gain not specified [RCV002052725] Chr21:15285841..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-21.3(chr21:15006457-28820583) copy number gain not specified [RCV002052722] Chr21:15006457..28820583 [GRCh37]
Chr21:21q11.2-21.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372)x3 copy number gain not provided [RCV001829203] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15006457-48097372) copy number gain not specified [RCV002052723] Chr21:15006457..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q11.2-21.3(chr21:15006457-29046428)x3 copy number gain See cases [RCV002287838] Chr21:15006457..29046428 [GRCh37]
Chr21:21q11.2-21.3		 pathogenic
GRCh37/hg19 21q21.1-21.3(chr21:21596314-26986899)x1 copy number loss not provided [RCV003483373] Chr21:21596314..26986899 [GRCh37]
Chr21:21q21.1-21.3		 uncertain significance
GRCh37/hg19 21q11.2-22.3(chr21:15006458-45674637)x3 copy number gain not provided [RCV003485218] Chr21:15006458..45674637 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q21.1-22.11(chr21:20408138-32852758)x3 copy number gain not provided [RCV003485220] Chr21:20408138..32852758 [GRCh37]
Chr21:21q21.1-22.11		 pathogenic
GRCh37/hg19 21q21.1-21.3(chr21:21437700-30474088)x3 copy number gain not provided [RCV003485221] Chr21:21437700..30474088 [GRCh37]
Chr21:21q21.1-21.3		 pathogenic
NC_000021.9:g.(25431701_?)_(?_26466216)dup duplication Alzheimer disease, early-onset, with cerebral amyloid angiopathy [RCV000019732] Chr21:25431701..26466216 [GRCh38]
Chr21:21q21.2-21.3		 pathogenic
GRCh37/hg19 21q11.2-22.3(chr21:15023401-48097372)x3 copy number gain not specified [RCV003986160] Chr21:15023401..48097372 [GRCh37]
Chr21:21q11.2-22.3		 pathogenic
GRCh37/hg19 21q21.3-22.3(chr21:26929299-48097372)x3 copy number gain not specified [RCV003986152] Chr21:26929299..48097372 [GRCh37]
Chr21:21q21.3-22.3		 pathogenic
miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
TCF4hsa-miR-155-5pOncomiRDBexternal_infoNANA21460854
WEE1hsa-miR-155-5pOncomiRDBexternal_infoNANA20668041
FOXO3hsa-miR-155-5pOncomiRDBexternal_infoNANA20371610
SOCS1hsa-miR-155-5pOncomiRDBexternal_infoNANA20354188
MLH1hsa-miR-155-5pOncomiRDBexternal_infoNANA20351277
SMAD5hsa-miR-155-5pOncomiRDBexternal_infoNANA20133617
INPP5Dhsa-miR-155-5pOncomiRDBexternal_infoNANA19890474
CEBPBhsa-miR-155-5pOncomiRDBexternal_infoNANA19711427
AGTR1hsa-miR-155-5pOncomiRDBexternal_infoNANA19177201
TP53INP1hsa-miR-155-5pOncomiRDBexternal_infoNANA17911264
IRAK3hsa-miR-155-3pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI20852130
AGTR1hsa-miR-155-3pMirecordsexternal_info{unchanged}NA16675453
BACH1hsa-miR-155-3pMirecordsexternal_infoNANA17881434
AGTR1hsa-miR-155-3pMirecordsexternal_info{unchanged}{unchanged}NA17588946
AGTR1hsa-miR-155-3pMirecordsexternal_infoNANA17668390
RHOAhsa-miR-155-3pMirecordsexternal_info{unchanged}NA18794355
ETS1hsa-miR-155-3pMirecordsexternal_infoNANA18950466
MEIS1hsa-miR-155-3pMirecordsexternal_info{unchanged}NA18950466
TAB2hsa-miR-155-3pMirecordsexternal_infoNANA19193853
CCN1hsa-miR-155-3pMirecordsexternal_info{changed}NA20452491
MYD88hsa-miR-155-3pMirecordsexternal_info{unchanged}NA20219467
FOXO3hsa-miR-155-3pMirecordsexternal_info{unchanged}NA20371610
SOCS1hsa-miR-155-3pMirecordsexternal_info{changed}NA20354188
FGF7hsa-miR-155-3pMirecordsexternal_infoNANA19701459
IKBKEhsa-miR-155-3pMirecordsexternal_info{changed}NA19650740
FADDhsa-miR-155-3pMirecordsexternal_info{unchanged}NA19650740
MECP2hsa-miR-155-3pMirecordsexternal_info{changed}NA19897480
CCND1hsa-miR-155-3pMirecordsexternal_infoNANA19538740
SPI1hsa-miR-155-3pMirecordsexternal_infoNANA19386588
UQCRFS1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI20550618
MEIS1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI18950466
MEIS1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)18668040
TAB2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI19193853
TAB2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCR//WeFunctional MTI20852130
TAB2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23449975
TAB2hsa-miR-155-5pMirtarbaseexternal_infoReporter assayFunctional MTI20680360
TAB2hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherNon-Functional MTI20584899
MECP2hsa-miR-155-5pMirtarbaseexternal_infoImmunohistochemistry//Luciferase reporter assay//qFunctional MTI19897480
MECP2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//MicroarrayFunctional MTI20388499
SOCS1hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI20354188
SOCS1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI22387553
SOCS1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22771905
MSH6hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blot//Northern Functional MTI20351277
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI19890474
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blot//Reporter Functional MTI20041145
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;Western Functional MTI19359473
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoGFP reporter assay//Luciferase reporter assay//NorFunctional MTI19641183
DET1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI18367535
DET1hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI20584899
SMAD5hsa-miR-155-5pMirtarbaseexternal_infoimmunoblot//Luciferase reporter assay//qRT-PCR//WeFunctional MTI20133617
SMAD5hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI20427544
ZIC3hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19177201
BACH1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//qRT-PCRFunctional MTI19193853
BACH1hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assayFunctional MTI18299402
BACH1hsa-miR-155-5pMirtarbaseexternal_infoImmunohistochemistry//In situ hybridization//LucifFunctional MTI21541331
BACH1hsa-miR-155-5pMirtarbaseexternal_infoReporter assayFunctional MTI17881434
BMAL1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)20584899
CSF1Rhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)20452491
CEBPBhsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI18299402
JARID2hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assayFunctional MTI19759154
JARID2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23185331
CSNK1A1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22350414
APChsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19136465
WDFY1hsa-miR-155-5pMirtarbaseexternal_infopSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
UBE2J1hsa-miR-155-5pMirtarbaseexternal_infopSILAC//ProteomicsFunctional MTI (Weak)18668040
PRAF2hsa-miR-155-5pMirtarbaseexternal_infopSILACFunctional MTI (Weak)18668040
PDLIM5hsa-miR-155-5pMirtarbaseexternal_infoWestern blotFunctional MTI20584899
MSI2hsa-miR-155-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI20584899
DNAJC19hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)20584899
CEBPBhsa-miR-155-5pMirtarbaseexternal_infoMicroarray//qRT-PCR//Western blotFunctional MTI19193853
CEBPBhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19596814
CEBPBhsa-miR-155-5pMirtarbaseexternal_infoELISA//Immunoblot//Immunocytochemistry//ImmunofluoFunctional MTI19887047
CDK5RAP3hsa-miR-155-5pMirtarbaseexternal_infoProteomics;OtherFunctional MTI (Weak)20584899
BRPF3hsa-miR-155-5pMirtarbaseexternal_infoProteomics//Western blotFunctional MTI17668390
BRPF3hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)17588946
BRPF3hsa-miR-155-5pMirtarbaseexternal_infoProteomics;OtherFunctional MTI (Weak)16675453
TM6SF1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI17881434
JADE1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherNon-Functional MTI17881434
RHOAhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI18794355
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assayFunctional MTI17668390
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Real time PCR//ReporterFunctional MTI17588946
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Quantitative pFunctional MTI20735984
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blot//Functional MTI16675453
AGTR1hsa-miR-155-5pMirtarbaseexternal_infoWestern blotFunctional MTI21310411
PKIAhsa-miR-155-5pMirtarbaseexternal_infoChIP-seq//Immunoblot//Luciferase reporter assay//qFunctional MTI22473996
TP53INP1hsa-miR-155-5pMirtarbaseexternal_infoWestern blot//Luciferase reporter assay//Reporter Functional MTI17911264
TP53INP1hsa-miR-155-5pMirtarbaseexternal_infoMicroarray//qRT-PCR//Western blotFunctional MTI21093163
IKBKEhsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI18753206
FGF7hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19701459
KDM3Ahsa-miR-155-5pMirtarbaseexternal_infoIn situ hybridization//Luciferase reporter assay//Functional MTI21541331
NFATC2IPhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayNon-Functional MTI17881434
CUX1hsa-miR-155-5pMirtarbaseexternal_infoMicroarray//qRT-PCRFunctional MTI (Weak)19193853
BCAT1hsa-miR-155-5pMirtarbaseexternal_infoMicroarrayFunctional MTI (Weak)19193853
SPI1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19386588
INPP5Dhsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI19359473
EDN1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19783678
FOXO3hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI20371610
FOXO3hsa-miR-155-5pMirtarbaseexternal_infoFlow//Immunoblot//Immunofluorescence//ImmunohistocFunctional MTI21304824
FOXO3hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19650740
JUNhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI22508041
IFNGR1hsa-miR-155-5pMirtarbaseexternal_infoFlow//Luciferase reporter assay//Northern blotFunctional MTI19877012
ETS1hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;Western blot;qRT-PCRFunctional MTI21310411
FLI1hsa-miR-155-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI18950466
CCN1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI20452491
ICAM1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayNon-Functional MTI19949084
ICAM1hsa-miR-155-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)21310411
SMAD2hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blot//Functional MTI21036908
MYBhsa-miR-155-5pMirtarbaseexternal_infoImmunohistochemistry//Luciferase reporter assay//NFunctional MTI21062812
SKIhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21466664
GCSAMhsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI22096245
IL13RA1hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21097505
BCL6hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23041630
MAP3K10hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23189122
MAP3K10hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23555551
NOS3hsa-miR-155-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI23108656
MYD88hsa-miR-155-5pMirtarbaseexternal_infoWestern blotFunctional MTI21030878
SMAD4hsa-miR-155-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI21036908
MAP3K14hsa-miR-155-5pMirtarbaseexternal_infoReporter assayFunctional MTI20584899
EEF1E1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19136465
AGRNhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)17881434
CCR9hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19193853
RSF1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)20209161
PDPRhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)20371610
FAM120Ahsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)18262046
CDH2hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19386588
TNPO1hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)21310411
GSK3Bhsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)19289835
ADAM10hsa-miR-155-5pMirtarbaseexternal_infoProteomicsFunctional MTI (Weak)21030878
NSD3hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI21030878
MASTLhsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI18668040
E2F2hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherNon-Functional MTI19759154
FAM135Ahsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI18950466
FAM135Ahsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherNon-Functional MTI21310411
C3orf18hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;OtherFunctional MTI21036908
C3orf18hsa-miR-155-5pMirtarbaseexternal_infoReporter assay;Western blotFunctional MTI20584899
SYPL1hsa-miR-155-5pTarbaseexternal_infoProteomicsPOSITIVE
TM6SF1hsa-miR-155-5pTarbaseexternal_infoReporter GenePOSITIVE
JADE1hsa-miR-155-5pTarbaseexternal_infoReporter GeneNEGATIVE
XAF1hsa-miR-155-5pTarbaseexternal_infoOtherPOSITIVE
SMAD3hsa-miR-155-5pTarbaseexternal_infoWesternblitNEGATIVE
ICAM1hsa-miR-155-5pTarbaseexternal_infoqPCRPOSITIVE
CD36hsa-miR-155-5pTarbaseexternal_infoWesternblitPOSITIVE
HDAC4hsa-miR-155-5pOncomiRDBexternal_infoNANA23169640
CDC73hsa-miR-155-5pOncomiRDBexternal_infoNANA23166327
APAF1hsa-miR-155-5pOncomiRDBexternal_infoNANA22996741
PIK3R1hsa-miR-155-5pOncomiRDBexternal_infoNANA22609116
SMAD2hsa-miR-155-5pOncomiRDBexternal_infoNANA22426647
CSNK1A1hsa-miR-155-5pOncomiRDBexternal_infoNANA22350414
BCL2hsa-miR-155-5pOncomiRDBexternal_infoNANA22139839
GCSAMhsa-miR-155-5pOncomiRDBexternal_infoNANA22096245
SOX6hsa-miR-155-5pOncomiRDBexternal_infoNANA21989846
PPP2CAhsa-miR-155-5pOncomiRDBexternal_infoNANA21806946
STAB1hsa-miR-155-5pOncomiRDBexternal_infoNANA21743493
KDM3Ahsa-miR-155-5pOncomiRDBexternal_infoNANA21541331
SKIhsa-miR-155-5pOncomiRDBexternal_infoNANA21466664

Predicted Targets
Summary Value
Count of predictions:21661
Count of gene targets:8369
Count of transcripts:15886
Interacting mature miRNAs:hsa-miR-155-3p, hsa-miR-155-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENST00000385060
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2125,573,980 - 25,574,044 (+)Ensembl
RefSeq Acc Id: NR_030784
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382125,573,980 - 25,574,044 (+)NCBI
GRCh372126,946,292 - 26,946,356 (+)ENTREZGENE
HuRef2112,349,435 - 12,349,499 (+)ENTREZGENE
CHM1_12126,506,960 - 26,507,024 (+)NCBI
T2T-CHM13v2.02123,931,556 - 23,931,620 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31542 AgrOrtholog
COSMIC MIR155 COSMIC
Ensembl Genes ENSG00000283904 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000385060 ENTREZGENE
GTEx ENSG00000283904 GTEx
HGNC ID HGNC:31542 ENTREZGENE
Human Proteome Map MIR155 Human Proteome Map
miRBase MI0000681 ENTREZGENE
NCBI Gene 406947 ENTREZGENE
OMIM 609337 OMIM
PharmGKB PA164722515 PharmGKB
RNAcentral URS000034309A RNACentral
  URS000062749E RNACentral
  URS0000D54CAD RNACentral