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Gene: FLI1 (Fli-1 proto-oncogene, ETS transcription factor) Homo sapiens
Symbol: FLI1
Name: Fli-1 proto-oncogene, ETS transcription factor
Description: Exhibits sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription, DNA-templated. Localizes to cytosol and nuclear body. Implicated in blood platelet disease and thrombocytopenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BDPLT21; Ewing sarcoma breakpoint region 2; EWSR2; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; proto-oncogene Fli-1; SIC-1; transcription factor ERGB
Mus musculus (house mouse) : Fli1 (Friend leukemia integration 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fli1 (Fli-1 proto-oncogene, ETS transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fli1 (Fli-1 proto-oncogene, ETS transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : FLI1 (Fli-1 proto-oncogene, ETS transcription factor)
Canis lupus familiaris (dog) : FLI1 (Fli-1 proto-oncogene, ETS transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fli1 (Fli-1 proto-oncogene, ETS transcription factor)
Sus scrofa (pig) : FLI1 (Fli-1 proto-oncogene, ETS transcription factor)
Chlorocebus sabaeus (African green monkey) : FLI1 (Fli-1 proto-oncogene, ETS transcription factor)
Heterocephalus glaber (naked mole-rat) : Fli1 (Fli-1 proto-oncogene, ETS transcription factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: FLI1 (Gene ID: 2313) and FLII (Gene ID: 2314) share the FLI1 symbol/alias in common. FLI1 is a widely used alternative name for FLII, actin remodeling protein (FLII), which can be confused with the official symbol for FLI1 (Fli-1 proto-oncogene, ETS transcription factor, GeneID 2313). [01 Jun 2018]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl11128,686,535 - 128,813,267 (+)EnsemblGRCh38hg38GRCh38
GRCh3811128,685,263 - 128,813,267 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711128,556,430 - 128,683,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611128,069,199 - 128,187,521 (+)NCBINCBI36hg18NCBI36
Build 3411128,069,198 - 128,187,520NCBI
Celera11125,728,561 - 125,849,286 (+)NCBI
Cytogenetic Map11q24.3NCBI
HuRef11124,504,750 - 124,631,960 (+)NCBIHuRef
CHM1_111128,442,436 - 128,569,169 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FLI1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320394
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.