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Gene: E2F2 (E2F transcription factor 2) Homo sapiens
Symbol: E2F2
Name: E2F transcription factor 2
Description: Exhibits proximal promoter sequence-specific DNA binding activity and transcription factor binding activity. Contributes to DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of sprouting angiogenesis and positive regulation of transcription by RNA polymerase II. Localizes to the RNA polymerase II transcription factor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E2F-2; transcription factor E2F2
Mus musculus (house mouse) : E2f2 (E2F transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : E2f2 (E2F transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f2 (E2F transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F2 (E2F transcription factor 2)
Canis lupus familiaris (dog) : E2F2 (E2F transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f2 (E2F transcription factor 2)
Sus scrofa (pig) : E2F2 (E2F transcription factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl123,506,438 - 23,531,233 (-)Ensembl
GRCh38123,505,696 - 23,531,250 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37123,832,920 - 23,857,712 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36123,705,509 - 23,730,300 (-)NCBINCBI36hg18NCBI36
Build 34123,578,227 - 23,603,019NCBI
Celera122,162,636 - 22,187,415 (-)NCBI
Cytogenetic Map1p36.12NCBI
HuRef122,083,477 - 22,108,254 (-)NCBIHuRef
CHM1_1123,945,595 - 23,970,369 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on E2F2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348982
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.