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Gene: CCND1 (cyclin D1) Homo sapiens
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Symbol: CCND1
Name: cyclin D1
Description: Exhibits several functions, including enzyme binding activity; proline-rich region binding activity; and transcription corepressor activity. Predicted to contribute to protein kinase activity. Involved in several processes, including mitotic G1 DNA damage checkpoint; positive regulation of cell cycle; and response to UV-A. Localizes to the cyclin-dependent protein kinase holoenzyme complex; nucleoplasm; and transcriptional repressor complex. Implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); invasive lobular carcinoma; pancreatic cancer (multiple); and von Hippel-Lindau disease. Biomarker of several diseases, including carcinoma (multiple); cervix uteri carcinoma in situ; hematologic cancer (multiple); invasive lobular carcinoma; and malignant glioma (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL-1 oncogene; BCL1; D11S287E; G1/S-specific cyclin D1; G1/S-specific cyclin-D1; PRAD1; PRAD1 oncogene; U21B31
Orthologs:
Mus musculus (house mouse) : Ccnd1 (cyclin D1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccnd1 (cyclin D1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccnd1 (cyclin D1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCND1 (cyclin D1)
Canis lupus familiaris (dog) : CCND1 (cyclin D1)
Sus scrofa (pig) : CCND1 (cyclin D1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381169,641,156 - 69,654,474 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371169,455,873 - 69,469,242 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,165,054 - 69,178,423 (+)NCBINCBI36hg18NCBI36
Build 341169,165,053 - 69,178,422NCBI
Celera1166,752,901 - 66,766,272 (+)NCBI
Cytogenetic Map11q13.3NCBI
HuRef1165,748,357 - 65,761,725 (+)NCBIHuRef
CHM1_11169,338,874 - 69,352,243 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations