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Gene: CEBPB (CCAAT enhancer binding protein beta) Homo sapiens
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Symbol: CEBPB
Name: CCAAT enhancer binding protein beta
RGD ID: 736208
Description: Exhibits RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of biomineral tissue development; positive regulation of sodium-dependent phosphate transport; and positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress. Localizes to nucleoplasm. Biomarker of Alzheimer's disease and rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c/EBP beta; C/EBP-beta; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer binding protein beta; CCAAT/enhancer-binding protein beta; CRP2; IL6DBP; interleukin 6-dependent DNA-binding protein; LAP; LIP; liver activator protein; liver-enriched inhibitory protein; liver-enriched transcriptional activator protein; MGC32080; NF-IL6; nuclear factor NF-IL6; nuclear factor of interleukin 6; TCF-5; TCF5; transcription factor 5; transcription factor C/EBP beta
Orthologs:
Mus musculus (house mouse) : Cebpb (CCAAT/enhancer binding protein (C/EBP), beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cebpb (CCAAT/enhancer binding protein beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cebpb (CCAAT enhancer binding protein beta)
Pan paniscus (bonobo/pygmy chimpanzee) : CEBPB (CCAAT enhancer binding protein beta)
Canis lupus familiaris (dog) : CEBPB (CCAAT enhancer binding protein beta)
Sus scrofa (pig) : CEBPB (CCAAT enhancer binding protein beta)
Chlorocebus sabaeus (African green monkey) : CEBPB (CCAAT enhancer binding protein beta)
Heterocephalus glaber (naked mole-rat) : Cebpb (CCAAT enhancer binding protein beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2050,190,830 - 50,192,668 (+)EnsemblGRCh38hg38GRCh38
GRCh382050,190,583 - 50,192,690 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372048,807,120 - 48,809,227 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362048,240,783 - 48,242,619 (+)NCBINCBI36hg18NCBI36
Build 342048,240,782 - 48,242,619NCBI
Celera2045,511,633 - 45,513,469 (+)NCBI
Cytogenetic Map20q13.13NCBI
HuRef2045,555,433 - 45,557,595 (+)NCBIHuRef
CHM1_12048,711,778 - 48,713,885 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CEBPB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736208
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.