(R)-noradrenaline increases expression ISO RGD:731721 6480464 Norepinephrine results in increased expression of CCN1 mRNA CTD PMID:15117851 (S)-nicotine increases expression ISO RGD:731721 6480464 Nicotine results in increased expression of CCN1 mRNA CTD PMID:17456735 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases expression ISO RGD:731721 6480464 2 more ... CTD PMID:20826375 1,2,4-trimethylbenzene increases expression ISO RGD:620763 6480464 pseudocumene results in increased expression of CCN1 protein CTD PMID:17337753 1,2-dimethylhydrazine multiple interactions ISO RGD:620763 6480464 [APC protein affects the susceptibility to 1, 2-Dimethylhydrazine] which results in decreased expression of CCN1 mRNA CTD PMID:27840820 1,2-dimethylhydrazine increases expression ISO RGD:731721 6480464 1, 2-Dimethylhydrazine results in increased expression of CYR61 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate increases expression ISO RGD:620763 6480464 1-Naphthylisothiocyanate results in increased expression of CCN1 mRNA CTD PMID:30723492 1-octadec-9-enoylglycero-3-phosphate increases expression ISO RGD:731721 6480464 lysophosphatidic acid results in increased expression of CCN1 protein CTD PMID:25822713 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RGD:731721 6480464 3-4-4-1-2-chlorophenylethoxycarbonyl amino-3-methyl-5-isoxazolyl benzylsulfanyl propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCN1 protein] CTD PMID:25822713 17alpha-ethynylestradiol affects expression ISO RGD:731721 6480464 Ethinyl Estradiol affects the expression of CCN1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:731721 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CCN1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:731721 6480464 Ethinyl Estradiol results in increased expression of CCN1 mRNA CTD PMID:14976129 , PMID:17942748 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of CCN1 mRNA CTD PMID:19153601 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of CCN1 mRNA CTD PMID:30165855 17beta-estradiol increases expression ISO RGD:731721 6480464 Estradiol results in increased expression of CCN1 mRNA, Estradiol results in increased expression of CYR61 mRNA CTD PMID:19484750 more ... 17beta-estradiol multiple interactions ISO RGD:731721 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of CCN1 mRNA] CTD PMID:20667977 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of CCN1 mRNA CTD PMID:19167446 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of CCN1 mRNA CTD PMID:22574217 17beta-estradiol affects expression ISO RGD:731721 6480464 Estradiol affects the expression of CCN1 mRNA CTD PMID:15598610 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:19095052 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731721 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CCN1 mRNA, Tetrachlorodibenzodioxin affects the reaction [AHR protein binds to CCN1 promoter] CTD PMID:17942748 , PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid 2-methyl-4-o-tolylazophenylamide] results in increased expression of CCN1 mRNA CTD PMID:29704546 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:731721 6480464 Tetrachlorodibenzodioxin results in decreased expression of CCN1 mRNA CTD PMID:19770486 , PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CCN1 mRNA CTD PMID:15056799 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731721 6480464 Tetrachlorodibenzodioxin results in increased expression of CCN1 mRNA CTD PMID:21496263 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731721 6480464 Tetrachlorodibenzodioxin affects the expression of CCN1 mRNA CTD PMID:16611356 , PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:620763 6480464 Tetrachlorodibenzodioxin affects the expression of CCN1 mRNA CTD PMID:22298810 2,4-diaminotoluene decreases expression ISO RGD:731721 6480464 2, 4-diaminotoluene results in decreased expression of CCN1 mRNA CTD PMID:20713471 2-butoxyethanol increases expression ISO RGD:731721 6480464 n-butoxyethanol results in increased expression of CCN1 mRNA CTD PMID:19812364 2-hydroxypropanoic acid increases expression EXP 6480464 Lactic Acid results in increased expression of CCN1 mRNA CTD PMID:30851411 2-methylcholine affects expression EXP 6480464 beta-methylcholine affects the expression of CCN1 mRNA CTD PMID:21179406 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:620763 6480464 3 more ... CTD PMID:23196670 3,3'-diindolylmethane affects methylation EXP 6480464 3, 3'-diindolylmethane affects the methylation of CCN1 promoter CTD PMID:24466240 3,4-dichloroaniline decreases expression EXP 6480464 3, 4-dichloroaniline results in decreased expression of CCN1 mRNA CTD PMID:24172598 3,4-methylenedioxymethamphetamine increases expression ISO RGD:731721 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of CCN1 mRNA CTD PMID:20188158 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:731721 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of CCN1 mRNA CTD PMID:20188158 3-methylcholanthrene increases expression ISO RGD:731721 6480464 Methylcholanthrene results in increased expression of CCN1 mRNA CTD PMID:20713471 4,4'-diaminodiphenylmethane increases expression ISO RGD:620763 6480464 4, 4'-diaminodiphenylmethane results in increased expression of CCN1 mRNA CTD PMID:30723492 4,4'-sulfonyldiphenol increases expression ISO RGD:731721 6480464 bis4-hydroxyphenylsulfone results in increased expression of CYR61 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol multiple interactions ISO RGD:731721 6480464 [bis4-hydroxyphenylsulfone co-treated with Tretinoin] results in decreased expression of CYR61 mRNA CTD PMID:30951980 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression EXP 6480464 Oxazolone results in increased expression of CCN1 mRNA CTD PMID:23999411 4-hydroxyphenyl retinamide increases expression ISO RGD:731721 6480464 Fenretinide results in increased expression of CCN1 mRNA CTD PMID:28973697 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of CCN1 mRNA, Fluorouracil results in increased expression of CCN1 protein CTD PMID:17699798 , PMID:24737281 5-fluorouracil affects response to substance EXP 6480464 CCN1 affects the susceptibility to Fluorouracil CTD PMID:15067352 6-propyl-2-thiouracil increases expression ISO RGD:620763 6480464 Propylthiouracil results in increased expression of CCN1 mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression ISO RGD:620763 6480464 Propylthiouracil results in decreased expression of CCN1 mRNA CTD PMID:25825206 6alpha-methylprednisolone increases expression EXP 6480464 Methylprednisolone results in increased expression of CCN1 mRNA CTD PMID:19192274 acetamide increases expression ISO RGD:620763 6480464 acetamide results in increased expression of CCN1 mRNA CTD PMID:31881176 acrylamide decreases expression ISO RGD:731721 6480464 Acrylamide results in decreased expression of CCN1 mRNA CTD PMID:30807115 afimoxifene multiple interactions EXP 6480464 GPER1 protein affects the reaction [afimoxifene results in increased expression of CCN1 mRNA] CTD PMID:19153601 afimoxifene increases expression EXP 6480464 afimoxifene results in increased expression of CCN1 mRNA CTD PMID:19153601 aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of CCN1 protein CTD PMID:20106945 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CCN1 mRNA CTD PMID:21632981 more ... aldehydo-D-glucose increases expression ISO RGD:731721 6480464 Glucose results in increased expression of CCN1 mRNA CTD PMID:17178593 aldrin increases expression ISO RGD:731721 6480464 Aldrin results in increased expression of CCN1 mRNA CTD PMID:18579281 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of CCN1 mRNA CTD PMID:21934132 all-trans-retinoic acid multiple interactions ISO RGD:731721 6480464 [bis4-hydroxyphenylsulfone co-treated with Tretinoin] results in decreased expression of CYR61 mRNA more ... CTD PMID:30951980 ammonium chloride affects expression ISO RGD:620763 6480464 Ammonium Chloride affects the expression of CCN1 mRNA CTD PMID:16483693 ampicillin increases expression EXP 6480464 Ampicillin results in increased expression of CCN1 mRNA CTD PMID:21632981 arsane increases expression ISO RGD:731721 6480464 Arsenic results in increased expression of CCN1 mRNA CTD PMID:23942117 arsenic atom increases expression ISO RGD:731721 6480464 Arsenic results in increased expression of CCN1 mRNA CTD PMID:23942117 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of CCN1 mRNA CTD PMID:20458559 avobenzone increases expression EXP 6480464 avobenzone results in increased expression of CCN1 mRNA CTD PMID:31016361 azathioprine increases expression EXP 6480464 Azathioprine results in increased expression of CCN1 mRNA CTD PMID:19192274 bacitracin affects expression ISO RGD:620763 6480464 Bacitracin affects the expression of CCN1 mRNA CTD PMID:18289764 bazedoxifene increases expression EXP 6480464 bazedoxifene results in increased expression of CCN1 mRNA CTD PMID:19914376 belinostat increases expression EXP 6480464 belinostat results in increased expression of CCN1 mRNA CTD PMID:23671600 benzo[a]pyrene decreases expression ISO RGD:731721 6480464 Benzoapyrene results in decreased expression of CCN1 mRNA CTD PMID:19770486 benzo[a]pyrene decreases methylation EXP 6480464 Benzoapyrene results in decreased methylation of CYR61 promoter CTD PMID:27901495 benzo[a]pyrene increases expression EXP 6480464 Benzoapyrene results in increased expression of CCN1 mRNA CTD PMID:19181443 more ... benzo[a]pyrene increases expression ISO RGD:731721 6480464 Benzoapyrene results in increased expression of CCN1 mRNA CTD PMID:20713471 more ... benzo[a]pyrene multiple interactions ISO RGD:731721 6480464 Benzoapyrene promotes the reaction [AHR protein binds to CCN1 promoter] CTD PMID:19654925 benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7 more ... CTD PMID:19150397 benzo[a]pyrene diol epoxide I increases expression EXP 6480464 7 more ... CTD PMID:26238291 benzo[b]fluoranthene increases expression ISO RGD:731721 6480464 benzobfluoranthene results in increased expression of CCN1 mRNA CTD PMID:26377693 beta-naphthoflavone multiple interactions ISO RGD:620763 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN1 mRNA CTD PMID:18164116 bexarotene decreases expression EXP 6480464 Bexarotene results in decreased expression of CCN1 mRNA CTD PMID:17178900 bisphenol A increases expression ISO RGD:731721 6480464 bisphenol A results in increased expression of CCN1 mRNA, bisphenol A results in increased expression of CYR61 mRNA CTD PMID:20826375 , PMID:30951980 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CCN1 mRNA CTD PMID:29275510 , PMID:29718440 bisphenol A multiple interactions ISO RGD:731721 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of CYR61 mRNA CTD PMID:30951980 bisphenol A increases methylation ISO RGD:620763 6480464 bisphenol A results in increased methylation of CCN1 gene CTD PMID:28505145 bisphenol A decreases expression ISO RGD:731721 6480464 bisphenol A results in decreased expression of CCN1 mRNA CTD PMID:25594700 bisphenol A increases expression ISO RGD:620763 6480464 bisphenol A results in increased expression of CCN1 mRNA CTD PMID:25181051 bisphenol F increases expression ISO RGD:731721 6480464 bisphenol F results in increased expression of CYR61 mRNA CTD PMID:30951980 bisphenol F multiple interactions ISO RGD:731721 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of CYR61 mRNA CTD PMID:30951980 buta-1,3-diene decreases expression ISO RGD:731721 6480464 1, 3-butadiene results in decreased expression of CCN1 mRNA CTD PMID:29038090 butan-1-ol multiple interactions EXP 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of CCN1 mRNA CTD PMID:29432896 C60 fullerene increases expression ISO RGD:620763 6480464 fullerene C60 results in increased expression of CCN1 mRNA CTD PMID:19167457 cadmium dichloride affects expression ISO RGD:620763 6480464 Cadmium Chloride affects the expression of CCN1 mRNA CTD PMID:22110744 cadmium dichloride decreases expression ISO RGD:620763 6480464 Cadmium Chloride results in decreased expression of CCN1 mRNA CTD PMID:25993096 cadmium sulfate decreases expression EXP 6480464 cadmium sulfate results in decreased expression of CCN1 mRNA CTD PMID:21783983 calciol increases expression ISO RGD:731721 6480464 Cholecalciferol results in increased expression of CCN1 mRNA CTD PMID:17170073 calciol decreases expression ISO RGD:731721 6480464 Cholecalciferol results in decreased expression of CCN1 mRNA CTD PMID:16508948 calcitriol decreases expression EXP 6480464 Calcitriol results in decreased expression of CCN1 mRNA CTD PMID:16002434 capecitabine decreases response to substance EXP 6480464 CCN1 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of CCN1 mRNA CTD PMID:24752500 , PMID:25979313 carbon nanotube increases expression ISO RGD:731721 6480464 Nanotubes, Carbon analog results in increased expression of CCN1 mRNA CTD PMID:25554681 carbon nanotube decreases expression ISO RGD:731721 6480464 Nanotubes, Carbon results in decreased expression of CCN1 mRNA CTD PMID:25620056 carbon nanotube affects expression ISO RGD:731721 6480464 Nanotubes, Carbon affects the expression of CCN1 mRNA CTD PMID:25554681 carbonyl sulfide increases expression ISO RGD:620763 6480464 carbonyl sulfide results in increased expression of CCN1 mRNA CTD PMID:19395590 casticin increases expression ISO RGD:731721 6480464 casticin results in increased expression of CCN1 mRNA CTD PMID:28444820 chelerythrine multiple interactions ISO RGD:731721 6480464 chelerythrine inhibits the reaction [Phenylephrine results in increased expression of CCN1 mRNA] CTD PMID:15117851 chloroprene decreases expression ISO RGD:731721 6480464 Chloroprene results in decreased expression of CCN1 mRNA CTD PMID:23125180 chloroquine increases expression ISO RGD:620763 6480464 Chloroquine results in increased expression of CCN1 mRNA CTD PMID:19393257 choline multiple interactions ISO RGD:731721 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCN1 gene CTD PMID:20938992 ciguatoxin CTX1B affects expression ISO RGD:731721 6480464 Ciguatoxins affects the expression of CCN1 mRNA CTD PMID:18353800 cisplatin increases expression ISO RGD:731721 6480464 Cisplatin results in increased expression of CCN1 mRNA CTD PMID:21151649 cisplatin multiple interactions EXP 6480464 Cisplatin promotes the reaction [jinfukang results in decreased expression of CCN1 mRNA], jinfukang promotes the reaction [Cisplatin results in decreased expression of CCN1 mRNA] CTD PMID:27392435 cisplatin decreases expression ISO RGD:620763 6480464 Cisplatin results in decreased expression of CCN1 mRNA CTD PMID:18289764 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of CCN1 mRNA CTD PMID:19320972 copper atom increases expression EXP 6480464 Copper results in increased expression of CCN1 mRNA CTD PMID:19747488 copper atom multiple interactions EXP 6480464 [NSC 689534 binds to Copper] which results in increased expression of CCN1 mRNA CTD PMID:20971185 copper(0) increases expression EXP 6480464 Copper results in increased expression of CCN1 mRNA CTD PMID:19747488 copper(0) multiple interactions EXP 6480464 [NSC 689534 binds to Copper] which results in increased expression of CCN1 mRNA CTD PMID:20971185 copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of CCN1 mRNA CTD PMID:17211630 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of CCN1 mRNA CTD PMID:19549813 coumestrol multiple interactions EXP 6480464 [Coumestrol co-treated with 2, 3-bis3'-hydroxybenzylbutyrolactone] results in decreased expression of CCN1 mRNA CTD PMID:19167446 crocidolite asbestos increases expression EXP 6480464 Asbestos, Crocidolite results in increased expression of CCN1 mRNA CTD PMID:18687144 , PMID:25351596 cumene multiple interactions ISO RGD:731721 6480464 [cumene co-treated with KRAS gene mutant form] results in decreased expression of CCN1 mRNA CTD PMID:18648096 cyanidin cation multiple interactions ISO RGD:731721 6480464 cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein] CTD PMID:32044269 cyanidin cation multiple interactions ISO RGD:620763 6480464 cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CCN1 protein] CTD PMID:32044269 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein] CTD PMID:21055460 cyclosporin A affects expression EXP 6480464 Cyclosporine affects the expression of CCN1 mRNA CTD PMID:20106945 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of CCN1 mRNA CTD PMID:21632981 , PMID:25562108 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of CCN1 mRNA CTD PMID:22147139 cyclosporin A increases expression ISO RGD:731721 6480464 Cyclosporine results in increased expression of CCN1 mRNA CTD PMID:19770486 cylindrospermopsin increases expression EXP 6480464 cylindrospermopsin results in increased expression of CCN1 mRNA CTD PMID:24921660 D-glucose increases expression ISO RGD:731721 6480464 Glucose results in increased expression of CCN1 mRNA CTD PMID:17178593 deoxynivalenol increases expression ISO RGD:731721 6480464 deoxynivalenol results in increased expression of CCN1 mRNA CTD PMID:15371230 dexamethasone increases expression ISO RGD:731721 6480464 Dexamethasone results in increased expression of CCN1 mRNA CTD PMID:22733784 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of CCN1 mRNA CTD PMID:20458559 dibenz[a,h]anthracene increases expression ISO RGD:731721 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate increases expression ISO RGD:731721 6480464 Dibutyl Phthalate results in increased expression of CCN1 mRNA CTD PMID:17361019 , PMID:21266533 diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of CCN1 mRNA CTD PMID:19192274 diclofenac affects expression EXP 6480464 Diclofenac affects the expression of CCN1 mRNA CTD PMID:24752500 diethylstilbestrol increases expression ISO RGD:620763 6480464 Diethylstilbestrol results in increased expression of CCN1 mRNA CTD PMID:21658437 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of CCN1 mRNA CTD PMID:24236059 dioxygen multiple interactions ISO RGD:731721 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CCN1 mRNA, [Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CCN1 mRNA CTD PMID:19640911 , PMID:30529165 diuron decreases expression EXP 6480464 Diuron metabolite results in decreased expression of CCN1 mRNA CTD PMID:24172598 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 doxifluridine decreases response to substance EXP 6480464 CCN1 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 doxorubicin increases expression ISO RGD:731721 6480464 Doxorubicin results in increased expression of CCN1 mRNA CTD PMID:25896364 endosulfan decreases expression ISO RGD:620763 6480464 Endosulfan results in decreased expression of CCN1 mRNA CTD PMID:29391264 Enterolactone multiple interactions EXP 6480464 [Coumestrol co-treated with 2, 3-bis3'-hydroxybenzylbutyrolactone] results in decreased expression of CCN1 mRNA CTD PMID:19167446 estriol increases expression ISO RGD:731721 6480464 Estriol results in increased expression of CCN1 mRNA CTD PMID:25575267 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of CCN1 mRNA CTD PMID:31059573 fenamidone increases expression ISO RGD:731721 6480464 fenamidone results in increased expression of CCN1 mRNA CTD PMID:27029645 fenofibrate decreases expression EXP 6480464 Fenofibrate results in decreased expression of CCN1 mRNA CTD PMID:25572481 fluoranthene multiple interactions ISO RGD:731721 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of CCN1 mRNA CTD PMID:28329830 folic acid multiple interactions ISO RGD:731721 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCN1 gene CTD PMID:20938992 formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of CCN1 mRNA CTD PMID:23416264 , PMID:23649840 furan decreases methylation ISO RGD:620763 6480464 furan results in decreased methylation of CCN1 gene CTD PMID:27387713 genistein decreases expression EXP 6480464 Genistein results in decreased expression of CCN1 mRNA CTD PMID:20884965 , PMID:22228119 gentamycin affects expression ISO RGD:620763 6480464 Gentamicins affects the expression of CCN1 mRNA CTD PMID:18289764 geranylgeraniol multiple interactions EXP 6480464 geranylgeraniol inhibits the reaction [Zoledronic Acid results in decreased expression of CCN1 protein] CTD PMID:19530242 glucose increases expression ISO RGD:731721 6480464 Glucose results in increased expression of CCN1 mRNA CTD PMID:17178593 glycidol decreases expression ISO RGD:620763 6480464 glycidol results in decreased expression of CCN1 mRNA CTD PMID:24915197 hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of CCN1 mRNA CTD PMID:20044591 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of CCN1 mRNA CTD PMID:12414654 hydrogen sulfide increases expression ISO RGD:731721 6480464 Hydrogen Sulfide results in increased expression of CYR61 mRNA CTD PMID:31843631 hydroquinone affects expression EXP 6480464 hydroquinone affects the expression of CCN1 mRNA CTD PMID:15452088 indole-3-methanol affects expression ISO RGD:620763 6480464 indole-3-carbinol affects the expression of CCN1 mRNA CTD PMID:21396975 irinotecan decreases response to substance EXP 6480464 CCN1 protein results in decreased susceptibility to Irinotecan CTD PMID:16734730 jaspamide multiple interactions EXP 6480464 jasplakinolide results in increased expression of and results in increased secretion of CCN1 protein, YAP1 protein affects the reaction [jasplakinolide results in increased expression of CCN1 protein] CTD PMID:24040060 jaspamide increases expression EXP 6480464 jasplakinolide results in increased expression of CCN1 mRNA CTD PMID:24040060 L-methionine multiple interactions ISO RGD:731721 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCN1 gene CTD PMID:20938992 lead diacetate affects expression ISO RGD:620763 6480464 lead acetate affects the expression of CCN1 mRNA CTD PMID:22641619 leflunomide increases expression EXP 6480464 Leflunomide results in increased expression of CCN1 mRNA CTD PMID:28988120 lipopolysaccharide multiple interactions EXP 6480464 Plant Extracts affects the reaction [Lipopolysaccharides affects the expression of CCN1 mRNA] CTD PMID:28070326 lipopolysaccharide decreases expression ISO RGD:731721 6480464 Lipopolysaccharides results in decreased expression of CCN1 mRNA CTD PMID:27339419 lipopolysaccharide affects expression EXP 6480464 Lipopolysaccharides affects the expression of CCN1 mRNA CTD PMID:28070326 LY294002 multiple interactions EXP 6480464 2-4-morpholinyl-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein] CTD PMID:21055460 menadione increases expression EXP 6480464 Vitamin K 3 results in increased expression of CCN1 mRNA CTD PMID:12414654 mercury dibromide increases expression EXP 6480464 mercuric bromide results in increased expression of CCN1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of CCN1 mRNA CTD PMID:27188386 methamphetamine multiple interactions ISO RGD:620763 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA CTD PMID:19564919 methamphetamine increases expression ISO RGD:620763 6480464 Methamphetamine results in increased expression of CCN1 mRNA CTD PMID:19564919 methapyrilene increases expression ISO RGD:620763 6480464 Methapyrilene results in increased expression of CCN1 mRNA CTD PMID:30467583 methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of CCN1 mRNA CTD PMID:19192274 methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of CCN1 mRNA CTD PMID:23649840 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of CCN1 mRNA CTD PMID:28001369 methylparaben decreases expression EXP 6480464 methylparaben results in decreased expression of CCN1 mRNA CTD PMID:31745603 mono(2-ethylhexyl) phthalate increases expression ISO RGD:620763 6480464 mono-2-ethylhexylphthalate results in increased expression of CCN1 mRNA CTD PMID:16809437 N-acetyl-L-cysteine multiple interactions EXP 6480464 2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein] more ... CTD PMID:21055460 N-acetyl-L-cysteine increases expression EXP 6480464 Acetylcysteine results in increased expression of CCN1 mRNA, Acetylcysteine results in increased expression of CCN1 protein CTD PMID:21055460 N-methyl-4-phenylpyridinium decreases expression ISO RGD:620763 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of CCN1 mRNA CTD PMID:28801915 N-nitrosodiethylamine multiple interactions ISO RGD:620763 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN1 mRNA CTD PMID:18164116 naphthalene increases expression ISO RGD:731721 6480464 naphthalene results in increased expression of CCN1 mRNA CTD PMID:18978301 naphthalenes increases expression ISO RGD:620763 6480464 Naphthalenes results in increased expression of CCN1 protein CTD PMID:17337753 nickel atom increases expression ISO RGD:731721 6480464 Nickel results in increased expression of CCN1 mRNA CTD PMID:12540486 nickel atom increases expression EXP 6480464 Nickel results in increased expression of CCN1 mRNA CTD PMID:24768652 , PMID:25583101 nicotine increases expression ISO RGD:731721 6480464 Nicotine results in increased expression of CCN1 mRNA CTD PMID:17456735 orphenadrine affects expression ISO RGD:620763 6480464 Orphenadrine affects the expression of CCN1 mRNA CTD PMID:23665939 oxaliplatin multiple interactions ISO RGD:620763 6480464 [Oxaliplatin co-treated with Topotecan] results in increased expression of CCN1 mRNA CTD PMID:25729387 p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of CCN1 mRNA CTD PMID:27188386 paclitaxel increases response to substance EXP 6480464 CCN1 protein results in increased susceptibility to Paclitaxel CTD PMID:16734730 palbociclib increases expression EXP 6480464 palbociclib results in increased expression of CCN1 mRNA CTD PMID:22869556 paracetamol affects expression ISO RGD:731721 6480464 Acetaminophen affects the expression of CCN1 mRNA CTD PMID:17562736 paracetamol multiple interactions ISO RGD:731721 6480464 PANX1 gene mutant form promotes the reaction [Acetaminophen results in increased expression of CCN1 mRNA] CTD PMID:29246445 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CCN1 mRNA CTD PMID:21420995 , PMID:29067470 paracetamol increases expression ISO RGD:731721 6480464 Acetaminophen results in increased expression of CCN1 mRNA CTD PMID:11264010 more ... paraquat increases expression ISO RGD:731721 6480464 Paraquat results in increased expression of CCN1 mRNA CTD PMID:12595580 perfluorononanoic acid increases expression EXP 6480464 perfluorononanoic acid results in increased expression of CCN1 mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of CCN1 mRNA CTD PMID:27153767 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of CCN1 protein CTD PMID:26879310 phenobarbital multiple interactions ISO RGD:731721 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CCN1 mRNA] CTD PMID:19482888 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of CCN1 mRNA CTD PMID:19084549 phenobarbital decreases expression ISO RGD:731721 6480464 Phenobarbital results in decreased expression of CCN1 mRNA CTD PMID:25270620 phenobarbital increases expression ISO RGD:731721 6480464 Phenobarbital results in increased expression of CCN1 mRNA CTD PMID:19482888 phenylephrine multiple interactions ISO RGD:731721 6480464 2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of CCN1 mRNA] more ... CTD PMID:15117851 phenylephrine increases expression ISO RGD:731721 6480464 Phenylephrine results in increased expression of CCN1 mRNA, Phenylephrine results in increased expression of CCN1 protein CTD PMID:15117851 phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of CCN1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of CCN1 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:731721 6480464 2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCN1 mRNA] CTD PMID:15117851 phorbol 13-acetate 12-myristate increases expression ISO RGD:731721 6480464 Tetradecanoylphorbol Acetate results in increased expression of CCN1 mRNA CTD PMID:15117851 phosgene affects expression ISO RGD:731721 6480464 Phosgene affects the expression of CCN1 mRNA CTD PMID:16300373 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CCN1 mRNA CTD PMID:19710929 piroxicam increases expression EXP 6480464 Piroxicam results in increased expression of CCN1 mRNA CTD PMID:19192274 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of CCN1 protein CTD PMID:23718831 prednisolone increases expression EXP 6480464 Prednisolone results in increased expression of CCN1 mRNA CTD PMID:19192274 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:731721 6480464 Pregnenolone Carbonitrile results in decreased expression of CCN1 mRNA CTD PMID:28903501 propiconazole decreases expression ISO RGD:731721 6480464 propiconazole results in decreased expression of CCN1 mRNA CTD PMID:21278054 quercetin increases expression EXP 6480464 Quercetin results in increased expression of CCN1 mRNA CTD PMID:21632981 quinolin-8-ol increases expression EXP 6480464 Oxyquinoline results in increased expression of CCN1 mRNA CTD PMID:21632981 rac-lactic acid increases expression EXP 6480464 Lactic Acid results in increased expression of CCN1 mRNA CTD PMID:30851411 rifampicin multiple interactions EXP 6480464 [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA CTD PMID:21127053 ritodrine increases expression ISO RGD:731721 6480464 Ritodrine results in increased expression of CCN1 mRNA CTD PMID:23370008 rotenone increases expression ISO RGD:620763 6480464 Rotenone results in increased expression of CYR61 mRNA CTD PMID:28374803 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-5-benzo1 more ... CTD PMID:27188386 SCH 23390 multiple interactions ISO RGD:620763 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA CTD PMID:19564919 silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of CCN1 mRNA, Silicon Dioxide results in increased expression of CCN1 mRNA CTD PMID:25351596 , PMID:25895662 silicon dioxide decreases expression ISO RGD:731721 6480464 Silicon Dioxide results in decreased expression of CYR61 mRNA CTD PMID:29341224 silver atom increases expression EXP 6480464 Silver results in increased expression of CCN1 mRNA CTD PMID:26014281 , PMID:28959546 silver(0) increases expression EXP 6480464 Silver results in increased expression of CCN1 mRNA CTD PMID:26014281 , PMID:28959546 simvastatin multiple interactions EXP 6480464 Simvastatin inhibits the reaction [CCN1 results in increased expression of IL1B] more ... CTD PMID:20191585 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of CCN1 mRNA CTD PMID:17428261 sodium arsenate decreases expression ISO RGD:731721 6480464 sodium arsenate results in decreased expression of CCN1 mRNA CTD PMID:21795629 sodium arsenite decreases expression ISO RGD:731721 6480464 sodium arsenite results in decreased expression of CCN1 mRNA CTD PMID:18812580 sodium arsenite affects methylation EXP 6480464 sodium arsenite affects the methylation of CCN1 gene CTD PMID:28589171 sodium arsenite affects expression ISO RGD:731721 6480464 sodium arsenite affects the expression of CCN1 mRNA CTD PMID:16507464 sodium arsenite increases expression ISO RGD:731721 6480464 sodium arsenite results in increased expression of CCN1 mRNA CTD PMID:25270620 sodium aurothiomalate increases expression EXP 6480464 Gold Sodium Thiomalate results in increased expression of CCN1 mRNA CTD PMID:19192274 sodium dodecyl sulfate increases expression EXP 6480464 Sodium Dodecyl Sulfate results in increased expression of CCN1 mRNA CTD PMID:31734321 Soman increases expression ISO RGD:620763 6480464 Soman results in increased expression of CCN1 mRNA CTD PMID:19281266 succimer multiple interactions EXP 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of CCN1 mRNA CTD PMID:26378955 succimer multiple interactions ISO RGD:731721 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CCN1 mRNA CTD PMID:26378955 tamoxifen increases expression ISO RGD:731721 6480464 Tamoxifen results in increased expression of CCN1 mRNA CTD PMID:25123088 tamoxifen affects expression ISO RGD:731721 6480464 Tamoxifen affects the expression of CCN1 mRNA CTD PMID:17555576 , PMID:20937368 tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of CCN1 mRNA CTD PMID:12414654 , PMID:15336504 testosterone increases expression ISO RGD:731721 6480464 Testosterone results in increased expression of CCN1 mRNA CTD PMID:15788153 tetrachloromethane increases expression ISO RGD:731721 6480464 Carbon Tetrachloride results in increased expression of CCN1 mRNA CTD PMID:31919559 tetradecane increases expression ISO RGD:620763 6480464 n-tetradecane results in increased expression of CCN1 protein CTD PMID:17337753 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of CCN1 mRNA CTD PMID:29453283 thimerosal increases expression EXP 6480464 Thimerosal results in increased expression of CCN1 mRNA CTD PMID:16870260 thioacetamide increases expression ISO RGD:620763 6480464 Thioacetamide results in increased expression of CCN1 mRNA CTD PMID:23411599 titanium dioxide increases expression ISO RGD:731721 6480464 titanium dioxide results in increased expression of CCN1 mRNA CTD PMID:23557971 , PMID:27760801 titanium dioxide decreases expression ISO RGD:620763 6480464 titanium dioxide results in decreased expression of CCN1 mRNA CTD PMID:30012374 topotecan increases expression ISO RGD:620763 6480464 Topotecan results in increased expression of CCN1 mRNA CTD PMID:25729387 topotecan multiple interactions ISO RGD:620763 6480464 [Oxaliplatin co-treated with Topotecan] results in increased expression of CCN1 mRNA CTD PMID:25729387 torcetrapib increases expression EXP 6480464 torcetrapib results in increased expression of CCN1 mRNA CTD PMID:19164467 , PMID:23228038 trichloroethene decreases expression ISO RGD:731721 6480464 Trichloroethylene results in decreased expression of CCN1 mRNA CTD PMID:25549359 trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of CCN1 mRNA CTD PMID:26705709 troglitazone decreases expression EXP 6480464 Troglitazone results in decreased expression of CCN1 mRNA CTD PMID:19140230 , PMID:25572481 undecane increases expression ISO RGD:620763 6480464 undecane results in increased expression of CCN1 protein CTD PMID:17337753 urethane decreases expression EXP 6480464 Urethane results in decreased expression of CCN1 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:731721 6480464 Valproic Acid affects the expression of CCN1 mRNA CTD PMID:17292431 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of CCN1 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of CCN1 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:731721 6480464 Valproic Acid results in increased expression of CCN1 mRNA CTD PMID:24896083 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of CCN1 mRNA CTD PMID:25979313 vanadium atom decreases expression EXP 6480464 Vanadium results in decreased expression of CCN1 mRNA CTD PMID:19000753 vanadium(0) decreases expression EXP 6480464 Vanadium results in decreased expression of CCN1 mRNA CTD PMID:19000753 vancomycin decreases expression ISO RGD:620763 6480464 Vancomycin results in decreased expression of CCN1 mRNA CTD PMID:18289764 verteporfin decreases expression EXP 6480464 Verteporfin results in decreased expression of CCN1 mRNA CTD PMID:29725256 verteporfin multiple interactions ISO RGD:731721 6480464 Verteporfin inhibits the reaction [1 more ... CTD PMID:29893953 verteporfin multiple interactions EXP 6480464 Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN1 mRNA] CTD PMID:29725256 vinclozolin increases expression ISO RGD:620763 6480464 vinclozolin results in increased expression of CCN1 mRNA CTD PMID:23555832 vinclozolin decreases expression ISO RGD:620763 6480464 vinclozolin results in decreased expression of CCN1 mRNA CTD PMID:23034163 zoledronic acid multiple interactions EXP 6480464 CCN1 protein affects the reaction [Zoledronic Acid results in decreased phosphorylation of and results in decreased activity of AKT1 protein] more ... CTD PMID:19530242 zoledronic acid decreases expression EXP 6480464 Zoledronic Acid results in decreased expression of CCN1 mRNA, Zoledronic Acid results in decreased expression of CCN1 protein CTD PMID:19530242
