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Gene: NSD3 (nuclear receptor binding SET domain protein 3) Homo sapiens
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Symbol: NSD3
Name: nuclear receptor binding SET domain protein 3
Description: Exhibits histone-lysine N-methyltransferase activity and transcription coactivator activity. Involved in histone methylation; positive regulation of histone H3-K36 trimethylation; and positive regulation of transcription, DNA-templated. Localizes to the nucleus. Implicated in myeloid leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp667H044; FLJ20353; histone-lysine N-methyltransferase NSD3; KMT3F; KMT3G; MGC126766; MGC142029; nuclear SET domain-containing protein 3; pp14328; whistle; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; WHSC1-like protein 1; WHSC1L1; Wolf-Hirschhorn syndrome candidate 1-like 1; Wolf-Hirschhorn syndrome candidate 1-like 1 protein; wolf-Hirschhorn syndrome candidate 1-like protein 1
Orthologs:
Mus musculus (house mouse) : Nsd3 (nuclear receptor binding SET domain protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nsd3 (nuclear receptor binding SET domain protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nsd3 (nuclear receptor binding SET domain protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NSD3 (nuclear receptor binding SET domain protein 3)
Canis lupus familiaris (dog) : NSD3 (nuclear receptor binding SET domain protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nsd3 (nuclear receptor binding SET domain protein 3)
Sus scrofa (pig) : NSD3 (nuclear receptor binding SET domain protein 3)
Chlorocebus sabaeus (African green monkey) : NSD3 (nuclear receptor binding SET domain protein 3)
Heterocephalus glaber (naked mole-rat) : Nsd3 (nuclear receptor binding SET domain protein 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl838,269,704 - 38,382,272 (-)Ensembl
GRCh38838,269,704 - 38,382,272 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37838,127,217 - 38,239,872 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36838,251,717 - 38,358,947 (-)NCBINCBI36hg18NCBI36
Build 34838,251,716 - 38,358,947NCBI
Celera837,085,612 - 37,192,859 (-)NCBI
Cytogenetic Map8p11.23NCBI
HuRef836,666,622 - 36,774,003 (-)NCBIHuRef
CHM1_1838,334,565 - 38,441,681 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NSD3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319069
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.