CYP4A22 (cytochrome P450 family 4 subfamily A member 22) - Rat Genome Database
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Gene: CYP4A22 (cytochrome P450 family 4 subfamily A member 22) Homo sapiens
Analyze
Symbol: CYP4A22
Name: cytochrome P450 family 4 subfamily A member 22
RGD ID: 1603864
HGNC Page HGNC
Description: Exhibits 16-hydroxypalmitate dehydrogenase activity and laurate hydroxylase activity. Involved in lipid hydroxylation. Localizes to extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CYPIVA22; cytochrome P450 4A22; cytochrome P450 4A22K; cytochrome P450, family 4, subfamily A, polypeptide 22; fatty acid omega-hydroxylase; lauric acid omega-hydroxylase; long-chain fatty acid omega-monooxygenase
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl147,137,435 - 47,149,735 (+)EnsemblGRCh38hg38GRCh38
GRCh38147,137,441 - 47,149,738 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37147,603,113 - 47,615,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36147,375,694 - 47,387,113 (+)NCBINCBI36hg18NCBI36
Cytogenetic Map1p33NCBI
HuRef145,718,762 - 45,730,181 (+)NCBIHuRef
CHM1_1147,719,831 - 47,731,260 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1-benzylpiperazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-dinitrotoluene  (ISO)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (ISO)
20-HETE  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-phenoxybenzoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-tert-Octylphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
Aroclor 1254  (ISO)
atrazine  (ISO)
barium sulfate  (ISO)
benoxaprofen  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
buspirone  (ISO)
Butylbenzyl phthalate  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
ciprofibrate  (ISO)
climbazole  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cortisol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
dehydroepiandrosterone  (ISO)
dehydroepiandrosterone sulfate  (ISO)
deoxycholic acid  (ISO)
Diallyl sulfide  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
diquat  (ISO)
dodecanoic acid  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
farnesol  (ISO)
felbamate  (ISO)
fenofibrate  (EXP,ISO)
fenvalerate  (ISO)
fipronil  (EXP,ISO)
flutamide  (ISO)
fomepizole  (ISO)
fructose  (ISO)
furan  (ISO)
gabapentin  (ISO)
gadolinium trichloride  (ISO)
gemfibrozil  (ISO)
glafenine  (ISO)
GW 4064  (ISO)
GW 6471  (ISO)
GW 7647  (ISO)
Heliotrine  (EXP)
hexadecanoic acid  (ISO)
indole-3-methanol  (ISO)
kojic acid  (ISO)
lansoprazole  (ISO)
lead nitrate  (ISO)
leflunomide  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
nafenopin  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
O-methyleugenol  (EXP)
okadaic acid  (ISO)
oleic acid  (ISO)
orotic acid  (ISO)
orphenadrine  (ISO)
p-tert-Amylphenol  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
pent-4-enoic acid  (ISO)
pentachlorophenol  (ISO)
perfluorobutyric acid  (ISO)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorohexanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (ISO)
phenobarbital  (ISO)
phenylephrine  (ISO)
phenytoin  (ISO)
pirinixic acid  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propyzamide  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
Senkirkine  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
simazine  (ISO)
soybean oil  (ISO)
streptozocin  (ISO)
sucrose  (ISO)
Sudan III  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
Tautomycin  (ISO)
Tesaglitazar  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
zaragozic acid A  (ISO)

References

Additional References at PubMed
PMID:10860550   PMID:12464262   PMID:12477932   PMID:15128046   PMID:15611369   PMID:16806293   PMID:20079672   PMID:21820496   PMID:21873635   PMID:25187353   PMID:28514442   PMID:31199497  


Genomics

Comparative Map Data
CYP4A22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl147,137,435 - 47,149,735 (+)EnsemblGRCh38hg38GRCh38
GRCh38147,137,441 - 47,149,738 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37147,603,113 - 47,615,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36147,375,694 - 47,387,113 (+)NCBINCBI36hg18NCBI36
Cytogenetic Map1p33NCBI
HuRef145,718,762 - 45,730,181 (+)NCBIHuRef
CHM1_1147,719,831 - 47,731,260 (+)NCBICHM1_1
Cyp4a31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394115,420,824 - 115,436,212 (+)NCBIGRCm39mm39
GRCm39 Ensembl4115,420,846 - 115,436,212 (+)Ensembl
GRCm384115,563,627 - 115,579,015 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4115,563,649 - 115,579,015 (+)EnsemblGRCm38mm10GRCm38
MGSCv374115,236,322 - 115,251,619 (+)NCBIGRCm37mm9NCBIm37
MGSCv364115,061,581 - 115,076,946 (+)NCBImm8
Celera4114,302,851 - 114,318,308 (+)NCBICelera
Cytogenetic Map4D1NCBI
Cyp4a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25129,123,323 - 129,137,464 (+)NCBI
Rnor_6.0 Ensembl5134,492,756 - 134,507,154 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05134,492,734 - 134,507,158 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05138,283,577 - 138,297,981 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45135,901,653 - 135,915,754 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15135,906,849 - 135,920,979 (+)NCBI
Celera5127,661,027 - 127,675,153 (+)NCBICelera
Cytogenetic Map5q35NCBI
CYP4A22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1147,958,331 - 47,970,288 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl147,958,368 - 47,970,230 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0146,442,854 - 46,455,153 (+)NCBIMhudiblu_PPA_v0panPan3
CYP4A11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1513,604,130 - 13,676,344 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11513,663,337 - 13,676,350 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CYP4A90
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.16128,704,964 - 128,722,878 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26119,141,289 - 119,159,198 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
SHGC-74787  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37147,608,330 - 47,608,464UniSTSGRCh37
GRCh37147,401,778 - 47,401,912UniSTSGRCh37
Build 36147,174,365 - 47,174,499RGDNCBI36
Celera145,688,968 - 45,689,102RGD
Cytogenetic Map1p33UniSTS
HuRef145,517,911 - 45,518,045UniSTS
HuRef145,723,985 - 45,724,119UniSTS
TNG Radiation Hybrid Map126082.0UniSTS
GeneMap99-GB4 RH Map1145.5UniSTS
GDB:226298  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37147,610,296 - 47,611,579UniSTSGRCh37
GRCh37147,398,678 - 47,399,964UniSTSGRCh37
Build 36147,171,265 - 47,172,551RGDNCBI36
Celera145,685,871 - 45,687,154RGD
Cytogenetic Map1p33UniSTS
HuRef145,514,811 - 45,516,097UniSTS
HuRef145,725,951 - 45,727,234UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1562
Count of miRNA genes:552
Interacting mature miRNAs:580
Transcripts:ENST00000294337, ENST00000371890, ENST00000371891, ENST00000485117, ENST00000490948
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 383 383 1 383 106
Low 51 96 68 47 20 46 967 40 464 115 71 242 1 490 569
Below cutoff 1921 2328 1098 168 674 9 3064 1997 2973 78 1073 1024 160 711 2161

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000294337   ⟹   ENSP00000294337
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl147,137,455 - 47,146,483 (+)Ensembl
RefSeq Acc Id: ENST00000371890   ⟹   ENSP00000360957
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl147,137,450 - 47,149,275 (+)Ensembl
RefSeq Acc Id: ENST00000371891   ⟹   ENSP00000360958
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl147,137,441 - 47,149,727 (+)Ensembl
RefSeq Acc Id: ENST00000485117
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl147,137,435 - 47,148,864 (+)Ensembl
RefSeq Acc Id: ENST00000490948
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl147,137,435 - 47,148,864 (+)Ensembl
RefSeq Acc Id: ENST00000619754   ⟹   ENSP00000482952
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl147,137,454 - 47,147,402 (+)Ensembl
RefSeq Acc Id: ENST00000620131   ⟹   ENSP00000479019
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl147,137,463 - 47,149,735 (+)Ensembl
RefSeq Acc Id: NM_001010969   ⟹   NP_001010969
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,137,441 - 47,149,727 (+)NCBI
GRCh37147,603,107 - 47,614,528 (+)NCBI
Build 36147,375,694 - 47,387,113 (+)NCBI Archive
HuRef145,718,762 - 45,730,181 (+)ENTREZGENE
CHM1_1147,719,831 - 47,731,260 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001308102   ⟹   NP_001295031
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,137,441 - 47,147,482 (+)NCBI
CHM1_1147,719,831 - 47,729,888 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005270767   ⟹   XP_005270824
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,137,443 - 47,149,738 (+)NCBI
GRCh37147,603,107 - 47,614,528 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005270770   ⟹   XP_005270827
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,137,443 - 47,144,680 (+)NCBI
GRCh37147,603,107 - 47,614,528 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001737122
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,137,443 - 47,149,738 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001010969   ⟸   NM_001010969
- Peptide Label: isoform 1
- UniProtKB: Q5TCH4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005270824   ⟸   XM_005270767
- Peptide Label: isoform X1
- UniProtKB: Q5TCH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005270827   ⟸   XM_005270770
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001295031   ⟸   NM_001308102
- Peptide Label: isoform 2
- UniProtKB: Q5TCH4 (UniProtKB/Swiss-Prot),   A0A087WZX9 (UniProtKB/TrEMBL),   A5PKT5 (UniProtKB/TrEMBL),   A5PL05 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000479019   ⟸   ENST00000620131
RefSeq Acc Id: ENSP00000360957   ⟸   ENST00000371890
RefSeq Acc Id: ENSP00000360958   ⟸   ENST00000371891
RefSeq Acc Id: ENSP00000294337   ⟸   ENST00000294337
RefSeq Acc Id: ENSP00000482952   ⟸   ENST00000619754

Promoters
RGD ID:6855460
Promoter ID:EPDNEW_H895
Type:initiation region
Name:CYP4A22_1
Description:cytochrome P450 family 4 subfamily A member 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38147,137,459 - 47,137,519EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p34.3-33(chr1:39479787-47688131)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051817]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051817]|See cases [RCV000051817] Chr1:39479787..47688131 [GRCh38]
Chr1:39945459..48153803 [GRCh37]
Chr1:39718046..47926390 [NCBI36]
Chr1:1p34.3-33
pathogenic
NM_001010969.3(CYP4A22):c.1357G>A (p.Gly453Arg) single nucleotide variant Malignant melanoma [RCV000064803] Chr1:47146146 [GRCh38]
Chr1:47611818 [GRCh37]
Chr1:47384405 [NCBI36]
Chr1:1p33
not provided
NM_001010969.3(CYP4A22):c.1358G>A (p.Gly453Glu) single nucleotide variant Malignant melanoma [RCV000064804] Chr1:47146147 [GRCh38]
Chr1:47611819 [GRCh37]
Chr1:47384406 [NCBI36]
Chr1:1p33
not provided
NM_001010969.3(CYP4A22):c.1364+3G>A single nucleotide variant Malignant melanoma [RCV000064805] Chr1:47146156 [GRCh38]
Chr1:47611828 [GRCh37]
Chr1:47384415 [NCBI36]
Chr1:1p33
not provided
NM_001010969.3(CYP4A22):c.597G>A (p.Lys199=) single nucleotide variant Malignant melanoma [RCV000060207] Chr1:47143355 [GRCh38]
Chr1:47609027 [GRCh37]
Chr1:47381614 [NCBI36]
Chr1:1p33
not provided
NM_001010969.3(CYP4A22):c.987G>A (p.Gly329=) single nucleotide variant Malignant melanoma [RCV000060208] Chr1:47144639 [GRCh38]
Chr1:47610311 [GRCh37]
Chr1:47382898 [NCBI36]
Chr1:1p33
not provided
GRCh38/hg38 1p33(chr1:46969963-47200507)x3 copy number gain See cases [RCV000139371] Chr1:46969963..47200507 [GRCh38]
Chr1:47435635..47666179 [GRCh37]
Chr1:47208222..47438766 [NCBI36]
Chr1:1p33
likely benign
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3 copy number loss not provided [RCV000762767] Chr1:20608823..120546301 [GRCh37]
Chr1:1p36.12-12
likely benign
GRCh37/hg19 1p34.1-32.3(chr1:45303358-52157856)x1 copy number loss See cases [RCV000448358] Chr1:45303358..52157856 [GRCh37]
Chr1:1p34.1-32.3
likely pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p33-32.3(chr1:47272184-52505405)x1 copy number loss not provided [RCV001005086] Chr1:47272184..52505405 [GRCh37]
Chr1:1p33-32.3
pathogenic
GRCh37/hg19 1p36.22-21.1(chr1:103343285-103455144)x3 copy number gain Global developmental delay [RCV000787285] Chr1:103343285..103455144 [GRCh37]
Chr1:1p36.22-21.1
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:20575 AgrOrtholog
COSMIC CYP4A22 COSMIC
Ensembl Genes ENSG00000162365 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000294337 UniProtKB/TrEMBL
  ENSP00000360957 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000360958 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000479019 UniProtKB/TrEMBL
  ENSP00000482952 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENST00000294337 UniProtKB/TrEMBL
  ENST00000371890 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000371891 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000619754 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000620131 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000162365 GTEx
HGNC ID HGNC:20575 ENTREZGENE
Human Proteome Map CYP4A22 Human Proteome Map
InterPro Cyt_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_E_grp-II UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:284541 UniProtKB/Swiss-Prot
NCBI Gene 284541 ENTREZGENE
OMIM 615341 OMIM
Pfam p450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134979692 PharmGKB
PRINTS EP450I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EP450II UniProtKB/TrEMBL
  P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WUY4_HUMAN UniProtKB/TrEMBL
  A0A087WZX9 ENTREZGENE, UniProtKB/TrEMBL
  A0A0C4DFN9_HUMAN UniProtKB/TrEMBL
  A5PKT5 ENTREZGENE, UniProtKB/TrEMBL
  A5PL05 ENTREZGENE, UniProtKB/TrEMBL
  CP4AM_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q5TCH5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q5TCH3 UniProtKB/Swiss-Prot
  Q6JXK7 UniProtKB/Swiss-Prot
  Q6JXK8 UniProtKB/Swiss-Prot
  Q9NRM4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-15 CYP4A22  cytochrome P450 family 4 subfamily A member 22    cytochrome P450, family 4, subfamily A, polypeptide 22  Symbol and/or name change 5135510 APPROVED
2011-09-01 CYP4A22  cytochrome P450, family 4, subfamily A, polypeptide 22  CYP4A22  cytochrome P450, family 4, subfamily A, polypeptide 22  Symbol and/or name change 5135510 APPROVED