ADRB2 (adrenoceptor beta 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ADRB2 (adrenoceptor beta 2) Homo sapiens
Analyze
Symbol: ADRB2
Name: adrenoceptor beta 2
RGD ID: 733595
HGNC Page HGNC
Description: Enables several functions, including amyloid-beta binding activity; beta2-adrenergic receptor activity; and norepinephrine binding activity. Involved in several processes, including activation of adenylate cyclase activity; positive regulation of macroautophagy; and regulation of signal transduction. Located in Golgi apparatus and plasma membrane. Is integral component of plasma membrane. Part of receptor complex. Implicated in several diseases, including autoimmune disease (multiple); disease of metabolism (multiple); kidney failure (multiple); lung disease (multiple); and open-angle glaucoma (multiple). Biomarker of cholangiocarcinoma; chronic obstructive pulmonary disease; cystic fibrosis; and psoriasis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADRB2R; ADRBR; adrenergic receptor, beta 2; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2 surface; adrenoceptor beta 2, surface; B2AR; BAR; beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor; BETA2AR; catecholamine receptor
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5148,826,611 - 148,828,623 (+)EnsemblGRCh38hg38GRCh38
GRCh385148,826,611 - 148,828,623 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375148,206,174 - 148,208,186 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365148,186,349 - 148,188,381 (+)NCBINCBI36hg18NCBI36
Build 345148,186,368 - 148,188,379NCBI
Celera5144,288,206 - 144,290,248 (+)NCBI
Cytogenetic Map5q32NCBI
HuRef5143,352,751 - 143,354,793 (+)NCBIHuRef
CHM1_15147,638,640 - 147,640,684 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (IMP,ISO)
AIDS Dementia Complex  (EXP)
Angina Pectoris  (IMP)
asthma  (EXP,IAGP,IDA,IEA,ISO)
autistic disorder  (EXP)
Breast Neoplasms  (IEA)
bronchiolitis  (IDA)
cardiomyopathy  (EXP)
cardiovascular system disease  (IEA)
cholangiocarcinoma  (IEP)
chronic obstructive pulmonary disease  (IAGP,IDA,IEP,IMP)
congestive heart failure  (IAGP,ISO)
Coronary Disease  (IAGP)
cystic fibrosis  (IAGP,IEP)
dermatitis  (IAGP)
dilated cardiomyopathy  (EXP,ISO)
disease of metabolism  (IAGP)
end stage renal disease  (IDA)
Experimental Liver Cirrhosis  (ISO)
familial adenomatous polyposis 1  (IAGP)
familial hyperlipidemia  (EXP)
fatty liver disease  (IAGP)
Fibrosis  (EXP)
Graves' disease  (IAGP)
Hereditary Neoplastic Syndromes  (IAGP)
human immunodeficiency virus infectious disease  (EXP)
Hyperlipoproteinemia Type II  (IAGP)
hypertension  (IAGP,IEA,ISO)
Hypertriglyceridemia  (IEA)
hypokalemia  (EXP)
hypothyroidism  (ISO)
Insulin Resistance  (EXP,IAGP,ISO)
interstitial cystitis  (IAGP)
kidney disease  (ISO)
Left Ventricular Hypertrophy  (IAGP)
Liver Injury  (ISO)
lung disease  (EXP)
Metabolic Syndrome  (IAGP,IEA)
myasthenia gravis  (IAGP)
myocardial infarction  (IAGP,ISO)
Myocardial Ischemia  (EXP)
Myocardial Reperfusion Injury  (ISO)
myocarditis  (ISO)
Nasal Polyps  (IAGP)
nervous system disease  (EXP)
Neurodevelopmental Disorders  (IAGP)
obesity  (EXP,IAGP,IEA,ISO)
open-angle glaucoma  (IAGP)
Paroxysmal Dyspnea  (IAGP)
pneumonia  (ISO)
polycystic ovary syndrome  (ISO)
primary open angle glaucoma  (IAGP)
Prostatic Neoplasms  (EXP)
psoriasis  (IAGP,IEP)
pulmonary edema  (IAGP,ISO)
Reperfusion Injury  (ISO)
sciatic neuropathy  (ISO)
Sepsis  (ISO)
Stomach Neoplasms  (EXP)
toxic shock syndrome  (IAGP,IDA)
Tremor  (EXP)
type 2 diabetes mellitus  (IAGP,IEA)
ulcerative colitis  (ISO)
urticaria  (IAGP)
Ventricular Dysfunction, Left  (EXP)
Vestibulocochlear Nerve Injuries  (ISO)
viral encephalitis  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
(5-hydroxyindol-3-yl)acetic acid  (ISO)
(R)-adrenaline  (EXP,ISO)
(R)-noradrenaline  (EXP,ISO)
(R)-octopamine  (EXP)
(S)-nicotine  (EXP)
(S)-timolol (anhydrous)  (EXP)
1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol  (EXP)
1-nitropyrene  (EXP)
15-acetyldeoxynivalenol  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
1H-imidazole  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-(tert-butylamino)-1-(2-chlorophenyl)ethanol  (EXP)
2-hydroxypropanoic acid  (EXP)
3',5'-cyclic AMP  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol  (EXP)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (EXP,ISO)
acebutolol  (EXP)
acetamide  (ISO)
acetylsalicylic acid  (EXP)
acrylamide  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (EXP,ISO)
albuterol  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP)
alprenolol  (EXP,ISO)
amiodarone  (EXP)
ammonium chloride  (ISO)
aristolochic acid  (EXP)
arsenite(3-)  (EXP,ISO)
asbestos  (EXP)
atenolol  (EXP,ISO)
beclomethasone  (EXP)
befunolol  (EXP)
benazepril  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
Benzo[k]fluoranthene  (ISO)
betaxolol  (EXP)
bexarotene  (EXP)
bicalutamide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisoprolol  (EXP,ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
bosentan  (EXP)
budesonide  (ISO)
busulfan  (ISO)
butanal  (EXP)
cadmium dichloride  (EXP)
calcitriol  (EXP)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
carbon nanotube  (ISO)
carteolol  (EXP)
carvedilol  (EXP,ISO)
CGP 12177  (EXP,ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (EXP)
clenbuterol  (ISO)
clobenpropit  (EXP)
clofibrate  (ISO)
clorgyline  (EXP)
clothianidin  (EXP)
cobalt atom  (EXP)
colforsin daropate hydrochloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
corticosterone  (ISO)
crocidolite asbestos  (EXP)
crotonaldehyde  (EXP)
cycloheximide  (EXP)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
DDT  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (ISO)
dichlorine  (ISO)
diclofenac  (ISO)
dieldrin  (ISO)
dioxygen  (EXP,ISO)
dobutamine  (EXP)
dopamine  (ISO)
dorsomorphin  (EXP)
doxazosin  (ISO)
doxorubicin  (ISO)
enalaprilat dihydrate  (ISO)
endosulfan  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
fenoterol  (EXP,ISO)
fipronil  (EXP)
folic acid  (ISO)
fonofos  (EXP)
formoterol fumarate  (EXP,ISO)
furan  (ISO)
glucose  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hexane  (EXP)
histamine  (EXP,ISO)
ICI 118551  (EXP,ISO)
imipramine  (EXP)
Immepip  (EXP)
iodocyanopindolol  (EXP,ISO)
isoprenaline  (EXP,ISO)
ketotifen  (EXP)
L-methionine  (ISO)
labetalol  (EXP,ISO)
Licochalcone B  (EXP)
lipopolysaccharide  (EXP,ISO)
losartan  (ISO)
metaproterenol  (EXP)
methotrexate  (EXP)
methoxychlor  (ISO)
methylisothiazolinone  (EXP)
metoprolol  (EXP,ISO)
mifepristone  (ISO)
miquelianin  (EXP)
N,N-diethyl-m-toluamide  (EXP)
nadolol  (EXP)
nickel atom  (ISO)
nicotine  (EXP)
nitric oxide  (ISO)
octopamine  (EXP)
olodaterol  (EXP)
orciprenaline  (EXP)
orphenadrine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (EXP)
pentanal  (EXP)
perfluorooctanoic acid  (ISO)
phenylephrine  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
picrotoxin  (ISO)
pindolol  (EXP,ISO)
pirinixic acid  (ISO)
potassium atom  (EXP)
potassium chromate  (EXP)
practolol  (EXP)
progesterone  (ISO)
propafenone  (EXP)
propanal  (EXP)
propranolol  (EXP,ISO)
propranolol hydrochloride  (ISO)
prostaglandin E1  (EXP)
prostaglandin E2  (EXP)
putrescine  (EXP)
rac-lactic acid  (EXP)
reserpine  (ISO)
Salmeterol xinafoate  (EXP,ISO)
SB 431542  (EXP)
silicon dioxide  (EXP,ISO)
sodium atom  (ISO)
sodium dodecyl sulfate  (EXP)
sotalol  (EXP)
spermidine  (EXP)
spermine  (EXP)
streptozocin  (ISO)
sunitinib  (EXP)
synephrine  (ISO)
tamoxifen  (ISO)
terbufos  (EXP)
terbutaline  (EXP,ISO)
tetrachloroethene  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
tributylstannane  (EXP)
trichostatin A  (EXP)
triclosan  (EXP)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (EXP)
vincristine  (EXP)
vorinostat  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of adenylate cyclase activity  (IDA)
activation of transmembrane receptor protein tyrosine kinase activity  (TAS)
adenylate cyclase-activating adrenergic receptor signaling pathway  (IBA)
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (ISO)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (TAS)
adrenergic receptor signaling pathway  (IDA)
aging  (ISO)
associative learning  (ISO)
bone resorption  (IEA,ISO)
brown fat cell differentiation  (IEA,ISO)
cell surface receptor signaling pathway  (TAS)
cellular response to amyloid-beta  (IGI)
cellular response to hypoxia  (ISO)
desensitization of G protein-coupled receptor signaling pathway by arrestin  (IDA)
diaphragm contraction  (ISO)
diet induced thermogenesis  (IEA,ISO)
endosome to lysosome transport  (TAS)
estrous cycle  (ISO)
excitatory postsynaptic potential  (ISO)
female pregnancy  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
heat generation  (IEA,ISO)
liver development  (ISO)
liver regeneration  (ISO)
negative regulation of angiogenesis  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of interleukin-6 production  (ISO)
negative regulation of multicellular organism growth  (IEA,ISO)
negative regulation of ossification  (ISO)
negative regulation of platelet aggregation  (ISO)
negative regulation of smooth muscle contraction  (IBA,ISO)
negative regulation of tumor necrosis factor production  (ISO)
negative regulation of urine volume  (ISO)
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure  (IBA,ISO)
positive regulation of AMPA receptor activity  (IGI)
positive regulation of apoptotic process  (ISO)
positive regulation of ATPase activity  (ISO)
positive regulation of autophagosome maturation  (IDA)
positive regulation of bone mineralization  (IEA,ISO)
positive regulation of calcium ion import across plasma membrane  (ISO)
positive regulation of cAMP-dependent protein kinase activity  (TAS)
positive regulation of cell population proliferation  (ISO)
positive regulation of cold-induced thermogenesis  (ISS)
positive regulation of heart contraction  (ISO)
positive regulation of lipophagy  (IDA)
positive regulation of MAPK cascade  (IDA)
positive regulation of mini excitatory postsynaptic potential  (IEA)
positive regulation of potassium ion transport  (ISO)
positive regulation of protein kinase A signaling  (IGI)
positive regulation of protein serine/threonine kinase activity  (IGI)
positive regulation of skeletal muscle tissue growth  (ISO)
positive regulation of sodium ion transport  (ISO)
positive regulation of the force of heart contraction by epinephrine  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
receptor-mediated endocytosis  (IDA)
regulation of calcium ion transport  (ISO)
regulation of sensory perception of pain  (ISO)
regulation of sodium ion transport  (IEA,ISO)
regulation of synaptic vesicle exocytosis  (ISO)
regulation of systemic arterial blood pressure by norepinephrine-epinephrine  (ISO)
regulation of vein smooth muscle contraction  (ISO)
response to catecholamine  (ISO)
response to cold  (IEA,ISO)
response to dexamethasone  (ISO)
response to estrogen  (ISO)
response to hypoxia  (ISO)
response to monoamine  (ISO)
response to progesterone  (ISO)
response to psychosocial stress  (TAS)
response to testosterone  (ISO)
synaptic transmission, glutamatergic  (ISO)
vasodilation  (ISO)
wound healing  (ISO)

References

References - curated
1. Ahmet I, etal., J Pharmacol Exp Ther. 2008 May;325(2):491-9. Epub 2008 Feb 20.
2. Ahmet I, etal., J Pharmacol Exp Ther. 2009 Oct;331(1):178-85. Epub 2009 Jul 8.
3. Bachman ES, etal., Science 2002 Aug 2;297(5582):843-5.
4. Basu K, etal., J Allergy Clin Immunol. 2009 Dec;124(6):1188-94.e3. Epub .
5. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
6. Bossard F, etal., Am J Respir Cell Mol Biol. 2011 Jan;44(1):91-8. Epub 2010 Mar 4.
7. Bussu F, etal., Am J Rhinol. 2007 May-Jun;21(3):378-82.
8. Carroll CL, etal., Chest. 2009 May;135(5):1186-92. Epub 2008 Nov 24.
9. Castle A, etal., Life Sci. 2001 Jun 22;69(5):599-611.
10. Chen Y, etal., Am J Nephrol. 2010;32(1):23-30. Epub 2010 May 19.
11. Choucair-Jaafar N, etal., Br J Pharmacol. 2009 Dec;158(7):1683-94. doi: 10.1111/j.1476-5381.2009.00510.x. Epub .
12. Communal C, etal., Circulation. 1999 Nov 30;100(22):2210-2.
13. Dallongeville J, etal., J Clin Endocrinol Metab. 2003 Oct;88(10):4862-6.
14. Dedoussis GV, etal., Genet Test. 2006 Fall;10(3):192-9.
15. Donohue JF Respir Care. 2008 May;53(5):618-22; discussion 623-4.
16. Dorow P, etal., J Cardiovasc Pharmacol. 1990;16 Suppl 5:S36-44.
17. El-Armouche A and Eschenhagen T, Heart Fail Rev. 2009 Dec;14(4):225-41.
18. Fan H, etal., Chin J Integr Med. 2012 Jul;18(7):514-21. Epub 2012 Jul 7.
19. Feldman G, etal., BMC Pulm Med. 2010 Mar 8;10:11.
20. Ferchland A, etal., Nephron. 1998 Sep;80(1):46-50.
21. Frishman WH Am J Ther. 2008 Nov-Dec;15(6):565-76.
22. Ghanei M, etal., Inhal Toxicol. 2007 Aug;19(10):889-94.
23. Gjesing AP, etal., Diabetologia. 2007 Mar;50(3):563-8. Epub 2007 Jan 13.
24. GOA_HUMAN data from the GO Consortium
25. Guo X, etal., Hypertension. 2005 Apr;45(4):799-803. Epub 2005 Feb 7.
26. Heckbert SR, etal., Circulation. 2003 Apr 22;107(15):2021-4. Epub 2003 Apr 7.
27. Hewitt M, etal., Am J Respir Cell Mol Biol. 2010 Feb;42(2):243-9. Epub 2009 May 7.
28. Iaccarino G, etal., Clin Pharmacol Ther. 2006 Dec;80(6):633-45.
29. Inagaki Y, etal., Mol Vis. 2006 Jun 12;12:673-80.
30. Isaza C, etal., Methods Find Exp Clin Pharmacol. 2005 May;27(4):237-44.
31. Ito T, etal., Life Sci. 2006 Jul 24;79(9):905-12. Epub 2006 Apr 17.
32. Iwamoto N, etal., Clin Chim Acta. 2001 Dec;314(1-2):85-91.
33. Jazdzewski K, etal., Int J Mol Med. 2007 Jan;19(1):181-6.
34. Jiang L, etal., Biochemistry. 1996 Oct 8;35(40):13136-46.
35. Jindal DP, etal., Farmaco. 2003 Aug;58(8):557-62.
36. Kassahun WT, etal., Naunyn Schmiedebergs Arch Pharmacol. 2005 Nov;372(3):171-81. Epub 2005 Nov 15.
37. Kim HA, etal., Yonsei Med J. 2007 Dec 31;48(6):1079-81.
38. Kim WJ, etal., Eur Respir J. 2010 Jun 4.
39. Kim WJ, etal., Respir Med. 2009 Jan;103(1):98-103. Epub 2008 Sep 11.
40. Kitahara T, etal., Neurosci Res. 2012 Mar;72(3):221-6. doi: 10.1016/j.neures.2011.11.007. Epub 2011 Dec 8.
41. Liu N, etal., Zhonghua Gan Zang Bing Za Zhi. 2009 Sep;17(9):653-6.
42. Lou Y, etal., Hypertens Res. 2010 Aug 26.
43. Lu HL and Chiang CH, Injury. 2008 Sep;39(9):1062-70. Epub 2008 Mar 11.
44. Ma G, etal., Tohoku J Exp Med. 2008 Nov;216(3):223-30.
45. Manni L, etal., Auton Neurosci. 2005 Mar 31;118(1-2):79-87.
46. Martin AC, etal., J Asthma. 2008 Jun;45(5):383-8.
47. Masuo K, etal., Am J Hypertens. 2006 Oct;19(10):1084-91.
48. Michel MC, etal., J Cardiovasc Pharmacol. 1989 Mar;13(3):421-31.
49. Mieno S, etal., Ann Thorac Surg. 2002 Oct;74(4):1213-8.
50. Mieno S, etal., Scand Cardiovasc J. 2005 Oct;39(5):313-9.
51. Mokry M, etal., Med Sci Monit. 2008 Aug;14(8):CR392-8.
52. Moore PE, etal., Clin Transl Sci. 2008 Sep;1(2):155-61.
53. Nakada TA, etal., Am J Respir Crit Care Med. 2010 Jan 15;181(2):143-9. doi: 10.1164/rccm.200903-0332OC. Epub 2009 Oct 22.
54. Nakamura A, etal., Clin Sci (Lond). 2005 Dec;109(6):503-11.
55. Nakamura A, etal., Inflammation. 2009 Feb;32(1):12-9.
56. Nakamura A, etal., J Am Soc Nephrol. 2004 Feb;15(2):316-25.
57. Nakamura A, etal., J Nephrol. 2010 May-Jun;23(3):341-9.
58. Nakamura A, etal., Nephrol Dial Transplant. 2010 Mar;25(3):730-7. Epub 2009 Nov 3.
59. Nikolaev VO, etal., Science. 2010 Mar 26;327(5973):1653-7. Epub 2010 Feb 25.
60. Nishii M, etal., Circulation. 2006 Aug 29;114(9):936-44. Epub 2006 Aug 14.
61. O'Byrne PM, etal., J Allergy Clin Immunol. 2009 Dec;124(6):1217-21.
62. OMIM Disease Annotation Pipeline
63. Ozkur M, etal., J Dermatol Sci. 2004 Aug;35(2):162-4.
64. Papatheodorou A, etal., Clin Biochem. 2010 Jan;43(1-2):43-50. Epub 2009 Sep 10.
65. Pipeline to import KEGG annotations from KEGG into RGD
66. Qiu YY and Yin KS, Zhonghua Jie He He Hu Xi Za Zhi. 2008 Mar;31(3):201-5.
67. Rami A, etal., Neurosci Res. 2003 Dec;47(4):373-82.
68. Revelli JP, etal., Biochem J. 1991 Aug 1;277 ( Pt 3):625-9.
69. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
70. RGD automated import pipeline for gene-chemical interactions
71. Roguedas AM, etal., Acta Derm Venereol. 2006;86(5):447-8.
72. Sethi AA, etal., Pharmacogenet Genomics. 2005 Sep;15(9):633-45.
73. Steagall WK, etal., Pharmacogenet Genomics. 2007 Jun;17(6):425-30.
74. Stobdan T, etal., Respirology. 2010 May;15(4):651-8.
75. Sugaya K, etal., J Urol. 2002 Dec;168(6):2668-71.
76. Szczepankiewicz A, etal., J Appl Genet. 2009;50(3):275-81.
77. Takahashi H, etal., Br J Dermatol. 1996 Jun;134(6):1065-9.
78. Vacca G, etal., Ther Adv Respir Dis. 2009 Feb;3(1):3-10.
79. Wallukat G and Wollenberger A, J Allergy Clin Immunol. 1991 Oct;88(4):581-7.
80. Wu H, etal., J Hypertens. 2006 Jun;24(6):1041-7.
81. Xu BY, etal., Clin Exp Immunol. 2000 Jan;119(1):156-60.
82. Yang J, etal., Am J Physiol. 1999 Jul;277(1 Pt 2):R132-9.
83. Zee RY, etal., Genetics. 2005 Mar;169(3):1583-7. Epub 2004 Nov 1.
84. Zhang W, etal., Eur J Pharmacol. 2010 Feb 25;628(1-3):171-8. Epub 2009 Nov 24.
85. Zhang ZS, etal., J Pharmacol Exp Ther. 2001 Jul;298(1):188-96.
86. Zhu WJ, etal., Zhonghua Yi Xue Za Zhi. 2008 Aug 5;88(30):2099-102.
Additional References at PubMed
PMID:154   PMID:1371121   PMID:1663718   PMID:1848190   PMID:2154750   PMID:2470898   PMID:2471981   PMID:2540197   PMID:2541947   PMID:2564629   PMID:2823249   PMID:2831218  
PMID:2837466   PMID:3025863   PMID:3034889   PMID:7608160   PMID:7680566   PMID:7706471   PMID:7797501   PMID:7901205   PMID:7915137   PMID:8125298   PMID:8308019   PMID:8383511  
PMID:8386307   PMID:8557631   PMID:8662852   PMID:8672451   PMID:8892658   PMID:9228019   PMID:9235896   PMID:9399946   PMID:9507004   PMID:9560162   PMID:9671706   PMID:9819198  
PMID:9830057   PMID:9880537   PMID:9924018   PMID:10499588   PMID:10734107   PMID:10753752   PMID:10858453   PMID:11013230   PMID:11039642   PMID:11146000   PMID:11147800   PMID:11192234  
PMID:11214319   PMID:11229437   PMID:11230287   PMID:11238007   PMID:11246467   PMID:11246538   PMID:11258696   PMID:11278447   PMID:11278940   PMID:11288039   PMID:11306963   PMID:11309381  
PMID:11371409   PMID:11380082   PMID:11434877   PMID:11441182   PMID:11466580   PMID:11526121   PMID:11588219   PMID:11706779   PMID:11713122   PMID:11713125   PMID:11735081   PMID:11739457  
PMID:11775126   PMID:11775127   PMID:11778498   PMID:11785682   PMID:11798553   PMID:11798846   PMID:11809767   PMID:11809992   PMID:11821698   PMID:11821707   PMID:11836685   PMID:11854867  
PMID:11877451   PMID:11879211   PMID:11882399   PMID:11882663   PMID:11884023   PMID:11921496   PMID:11941312   PMID:11941588   PMID:11942593   PMID:11956670   PMID:12008746   PMID:12023679  
PMID:12030897   PMID:12036966   PMID:12065131   PMID:12075579   PMID:12077726   PMID:12080445   PMID:12082592   PMID:12083963   PMID:12083965   PMID:12106601   PMID:12111048   PMID:12140284  
PMID:12142540   PMID:12142723   PMID:12142724   PMID:12163475   PMID:12164325   PMID:12167654   PMID:12184796   PMID:12215468   PMID:12244098   PMID:12297500   PMID:12361188   PMID:12387862  
PMID:12390345   PMID:12391272   PMID:12394950   PMID:12409304   PMID:12422339   PMID:12428391   PMID:12429837   PMID:12436935   PMID:12439523   PMID:12441217   PMID:12474986   PMID:12477932  
PMID:12502697   PMID:12519093   PMID:12527744   PMID:12544508   PMID:12563174   PMID:12569260   PMID:12574108   PMID:12605574   PMID:12621035   PMID:12628991   PMID:12629568   PMID:12716862  
PMID:12727985   PMID:12740450   PMID:12807170   PMID:12822042   PMID:12824951   PMID:12832031   PMID:12835612   PMID:12869379   PMID:12885990   PMID:12888635   PMID:12900437   PMID:12905693  
PMID:13680034   PMID:14500986   PMID:14510910   PMID:14510956   PMID:14553962   PMID:14557486   PMID:14573333   PMID:14610472   PMID:14610528   PMID:14615367   PMID:14650112   PMID:14654844  
PMID:14655898   PMID:14657864   PMID:14665698   PMID:14678342   PMID:14678347   PMID:14693408   PMID:14709719   PMID:14715679   PMID:14734649   PMID:14748897   PMID:14981238   PMID:14981808  
PMID:15016730   PMID:15069780   PMID:15079793   PMID:15123695   PMID:15126009   PMID:15147203   PMID:15153795   PMID:15155261   PMID:15166301   PMID:15170877   PMID:15212591   PMID:15245435  
PMID:15248848   PMID:15249444   PMID:15282385   PMID:15284533   PMID:15297801   PMID:15323067   PMID:15329337   PMID:15334382   PMID:15342173   PMID:15355441   PMID:15364898   PMID:15388645  
PMID:15452121   PMID:15464701   PMID:15479221   PMID:15480094   PMID:15480095   PMID:15492118   PMID:15493717   PMID:15498794   PMID:15506640   PMID:15518545   PMID:15542284   PMID:15554460  
PMID:15557128   PMID:15563584   PMID:15578262   PMID:15596681   PMID:15618708   PMID:15634674   PMID:15638826   PMID:15644445   PMID:15687340   PMID:15703163   PMID:15719258   PMID:15782186  
PMID:15794198   PMID:15797659   PMID:15806595   PMID:15817484   PMID:15817638   PMID:15824464   PMID:15833737   PMID:15833937   PMID:15840289   PMID:15853829   PMID:15861037   PMID:15867853  
PMID:15879435   PMID:15896782   PMID:15917856   PMID:15920038   PMID:15931235   PMID:15932670   PMID:15939803   PMID:15946904   PMID:15956122   PMID:15959859   PMID:15976384   PMID:15987731  
PMID:15994241   PMID:16004558   PMID:16009000   PMID:16027244   PMID:16027735   PMID:16054001   PMID:16100145   PMID:16142389   PMID:16153394   PMID:16164442   PMID:16172412   PMID:16188057  
PMID:16189366   PMID:16197474   PMID:16205624   PMID:16207148   PMID:16227135   PMID:16251889   PMID:16280290   PMID:16280323   PMID:16286511   PMID:16289313   PMID:16301860   PMID:16322642  
PMID:16338281   PMID:16339181   PMID:16344560   PMID:16369119   PMID:16369120   PMID:16374847   PMID:16395068   PMID:16407241   PMID:16409205   PMID:16412099   PMID:16417856   PMID:16420563  
PMID:16448568   PMID:16449022   PMID:16461848   PMID:16467650   PMID:16493638   PMID:16537879   PMID:16551744   PMID:16554384   PMID:16563272   PMID:16569551   PMID:16571957   PMID:16573811  
PMID:16585076   PMID:16596417   PMID:16615274   PMID:16618831   PMID:16636198   PMID:16651467   PMID:16670773   PMID:16672841   PMID:16683069   PMID:16714291   PMID:16728691   PMID:16740612  
PMID:16741943   PMID:16754519   PMID:16763224   PMID:16771114   PMID:16772309   PMID:16779985   PMID:16783489   PMID:16849635   PMID:16873402   PMID:16875498   PMID:16893516   PMID:16894395  
PMID:16899844   PMID:16907703   PMID:16920721   PMID:16931635   PMID:16935688   PMID:16946993   PMID:16971769   PMID:16996249   PMID:17003099   PMID:17036337   PMID:17054017   PMID:17068824  
PMID:17075257   PMID:17077128   PMID:17094995   PMID:17099033   PMID:17117186   PMID:17130852   PMID:17132602   PMID:17138565   PMID:17148612   PMID:17150099   PMID:17159089   PMID:17170700  
PMID:17198546   PMID:17199132   PMID:17200117   PMID:17210860   PMID:17223428   PMID:17243909   PMID:17255556   PMID:17267840   PMID:17270896   PMID:17292646   PMID:17297203   PMID:17303378  
PMID:17329986   PMID:17336757   PMID:17345787   PMID:17347382   PMID:17356698   PMID:17374341   PMID:17378367   PMID:17383306   PMID:17428813   PMID:17439327   PMID:17460547   PMID:17493936  
PMID:17510209   PMID:17512307   PMID:17531924   PMID:17561373   PMID:17569809   PMID:17573413   PMID:17591269   PMID:17595424   PMID:17600229   PMID:17621313   PMID:17635908   PMID:17644825  
PMID:17664853   PMID:17666399   PMID:17667029   PMID:17673687   PMID:17700364   PMID:17703412   PMID:17716866   PMID:17824821   PMID:17845212   PMID:17883727   PMID:17885618   PMID:17890463  
PMID:17893006   PMID:17907319   PMID:17919552   PMID:17925066   PMID:17952055   PMID:17962519   PMID:17962520   PMID:17963627   PMID:17993585   PMID:17996646   PMID:17998016   PMID:17998459  
PMID:18024720   PMID:18029348   PMID:18034461   PMID:18059015   PMID:18065472   PMID:18068431   PMID:18075464   PMID:18086673   PMID:18156033   PMID:18156980   PMID:18193079   PMID:18199683  
PMID:18219297   PMID:18238958   PMID:18239290   PMID:18240029   PMID:18247304   PMID:18249219   PMID:18253135   PMID:18267980   PMID:18303970   PMID:18311486   PMID:18316360   PMID:18331634  
PMID:18334922   PMID:18362692   PMID:18379861   PMID:18383333   PMID:18393130   PMID:18399855   PMID:18413308   PMID:18413560   PMID:18423577   PMID:18426866   PMID:18440968   PMID:18454446  
PMID:18473266   PMID:18479335   PMID:18484422   PMID:18492292   PMID:18498711   PMID:18513389   PMID:18534365   PMID:18540901   PMID:18544533   PMID:18547522   PMID:18558635   PMID:18566454  
PMID:18579897   PMID:18589597   PMID:18591903   PMID:18611262   PMID:18615004   PMID:18622265   PMID:18625943   PMID:18636124   PMID:18640383   PMID:18647184   PMID:18678875   PMID:18679149  
PMID:18691306   PMID:18691971   PMID:18702008   PMID:18702968   PMID:18709160   PMID:18714823   PMID:18753860   PMID:18758858   PMID:18772317   PMID:18801735   PMID:18818748   PMID:18821565  
PMID:18841999   PMID:18849614   PMID:18855131   PMID:18931892   PMID:18936436   PMID:18937294   PMID:18940527   PMID:18974840   PMID:18977990   PMID:18996102   PMID:19019335   PMID:19028820  
PMID:19033440   PMID:19034036   PMID:19056482   PMID:19056576   PMID:19086053   PMID:19088492   PMID:19102885   PMID:19111454   PMID:19131662   PMID:19148102   PMID:19176359   PMID:19177262  
PMID:19183167   PMID:19186333   PMID:19190821   PMID:19238444   PMID:19247692   PMID:19254291   PMID:19258923   PMID:19263529   PMID:19264973   PMID:19275519   PMID:19284637   PMID:19301767  
PMID:19326508   PMID:19334040   PMID:19336370   PMID:19367093   PMID:19373110   PMID:19378229   PMID:19378975   PMID:19420105   PMID:19422106   PMID:19422388   PMID:19424180   PMID:19430548  
PMID:19441602   PMID:19450127   PMID:19474452   PMID:19476811   PMID:19477270   PMID:19479237   PMID:19491387   PMID:19514054   PMID:19527514   PMID:19538012   PMID:19553224   PMID:19555572  
PMID:19559392   PMID:19565482   PMID:19576569   PMID:19578796   PMID:19581316   PMID:19584355   PMID:19623647   PMID:19626351   PMID:19665031   PMID:19689078   PMID:19706446   PMID:19706508  
PMID:19710023   PMID:19723516   PMID:19729601   PMID:19730237   PMID:19745160   PMID:19763081   PMID:19779464   PMID:19779622   PMID:19781422   PMID:19783788   PMID:19832974   PMID:19862939  
PMID:19874574   PMID:19883298   PMID:19886995   PMID:19887115   PMID:19905915   PMID:19910613   PMID:19913121   PMID:19927042   PMID:19929724   PMID:19932356   PMID:19933216   PMID:19948975  
PMID:19956569   PMID:19956635   PMID:20023040   PMID:20044476   PMID:20044737   PMID:20054398   PMID:20067119   PMID:20078877   PMID:20087642   PMID:20119640   PMID:20129829   PMID:20135061  
PMID:20140262   PMID:20144152   PMID:20167428   PMID:20173430   PMID:20175796   PMID:20175803   PMID:20193676   PMID:20201926   PMID:20210814   PMID:20215008   PMID:20230274   PMID:20235788  
PMID:20237834   PMID:20300048   PMID:20308035   PMID:20335826   PMID:20345371   PMID:20352314   PMID:20353789   PMID:20374546   PMID:20384434   PMID:20395454   PMID:20395963   PMID:20399803  
PMID:20401689   PMID:20413987   PMID:20416077   PMID:20424170   PMID:20431605   PMID:20452482   PMID:20459474   PMID:20467565   PMID:20468064   PMID:20503287   PMID:20515505   PMID:20519311  
PMID:20519561   PMID:20521014   PMID:20523301   PMID:20536507   PMID:20537417   PMID:20537997   PMID:20538960   PMID:20544957   PMID:20546196   PMID:20559325   PMID:20565774   PMID:20590567  
PMID:20602615   PMID:20603037   PMID:20628086   PMID:20673868   PMID:20682155   PMID:20686604   PMID:20703737   PMID:20705341   PMID:20708651   PMID:20726983   PMID:20727557   PMID:20733053  
PMID:20734064   PMID:20736788   PMID:20738880   PMID:20739277   PMID:20803192   PMID:20816195   PMID:20829805   PMID:20831043   PMID:20885911   PMID:20929600   PMID:20930716   PMID:20981007  
PMID:21034538   PMID:21038778   PMID:21044781   PMID:21054877   PMID:21059181   PMID:21183077   PMID:21200338   PMID:21215823   PMID:21228869   PMID:21228876   PMID:21233811   PMID:21233812  
PMID:21262196   PMID:21289629   PMID:21298476   PMID:21330366   PMID:21337626   PMID:21362625   PMID:21385652   PMID:21394004   PMID:21406495   PMID:21414566   PMID:21426793   PMID:21436355  
PMID:21448689   PMID:21450583   PMID:21481814   PMID:21483652   PMID:21488193   PMID:21541288   PMID:21573230   PMID:21599570   PMID:21600547   PMID:21605442   PMID:21621562   PMID:21622536  
PMID:21626217   PMID:21703359   PMID:21722392   PMID:21772288   PMID:21801278   PMID:21807569   PMID:21816540   PMID:21829036   PMID:21857662   PMID:21868355   PMID:21868357   PMID:21868359  
PMID:21873635   PMID:21883537   PMID:21889352   PMID:21905268   PMID:21916780   PMID:21956331   PMID:21959333   PMID:21963428   PMID:21964067   PMID:21982743   PMID:21990357   PMID:22010988  
PMID:22020285   PMID:22031696   PMID:22048503   PMID:22075484   PMID:22115535   PMID:22167199   PMID:22179058   PMID:22190857   PMID:22192964   PMID:22194601   PMID:22199155   PMID:22210825  
PMID:22241475   PMID:22267580   PMID:22297552   PMID:22299391   PMID:22328447   PMID:22383665   PMID:22399228   PMID:22416031   PMID:22441538   PMID:22447021   PMID:22466342   PMID:22483689  
PMID:22495178   PMID:22500016   PMID:22552340   PMID:22559839   PMID:22564389   PMID:22582545   PMID:22584966   PMID:22613709   PMID:22624056   PMID:22628317   PMID:22647787   PMID:22683571  
PMID:22731644   PMID:22742717   PMID:22743651   PMID:22748765   PMID:22759790   PMID:22763735   PMID:22772314   PMID:22793522   PMID:22796455   PMID:22817959   PMID:22821646   PMID:22862293  
PMID:22864926   PMID:22881137   PMID:22883364   PMID:22884155   PMID:22900502   PMID:22948827   PMID:22950544   PMID:22985077   PMID:22994654   PMID:23020224   PMID:23056231   PMID:23151510  
PMID:23166351   PMID:23208550   PMID:23229623   PMID:23229733   PMID:23236378   PMID:23243208   PMID:23245479   PMID:23261005   PMID:23266473   PMID:23267209   PMID:23291003   PMID:23302795  
PMID:23318885   PMID:23330094   PMID:23374348   PMID:23382219   PMID:23384627   PMID:23438238   PMID:23448263   PMID:23463918   PMID:23515162   PMID:23527545   PMID:23548523   PMID:23548524  
PMID:23557075   PMID:23631811   PMID:23708524   PMID:23724117   PMID:23729404   PMID:23760429   PMID:23786226   PMID:23798571   PMID:23875540   PMID:23879802   PMID:23911093   PMID:23936460  
PMID:23964556   PMID:23989552   PMID:24003153   PMID:24012958   PMID:24016068   PMID:24056936   PMID:24114717   PMID:24131275   PMID:24182991   PMID:24190883   PMID:24206668   PMID:24228710  
PMID:24265091   PMID:24279851   PMID:24322328   PMID:24342311   PMID:24366725   PMID:24373571   PMID:24405750   PMID:24559182   PMID:24561123   PMID:24614156   PMID:24621682   PMID:24623205  
PMID:24681963   PMID:24691493   PMID:24714117   PMID:24722188   PMID:24727057   PMID:24749907   PMID:24760207   PMID:24782128   PMID:24823730   PMID:24831005   PMID:24885710   PMID:24889093  
PMID:24890187   PMID:24960039   PMID:24966013   PMID:24992184   PMID:25050597   PMID:25050782   PMID:25074500   PMID:25102170   PMID:25111792   PMID:25159081   PMID:25162199   PMID:25179535  
PMID:25186548   PMID:25203160   PMID:25220262   PMID:25233048   PMID:25260632   PMID:25342155   PMID:25362359   PMID:25366745   PMID:25408348   PMID:25418299   PMID:25425623   PMID:25501358  
PMID:25537131   PMID:25537861   PMID:25600430   PMID:25639860   PMID:25666616   PMID:25673629   PMID:25730298   PMID:25740347   PMID:25824473   PMID:25857770   PMID:25872592   PMID:25876703  
PMID:25893811   PMID:25894531   PMID:25910744   PMID:25979592   PMID:25985706   PMID:25993632   PMID:26031147   PMID:26058426   PMID:26071206   PMID:26098693   PMID:26109805   PMID:26161982  
PMID:26235677   PMID:26248277   PMID:26339405   PMID:26369942   PMID:26409918   PMID:26475619   PMID:26526356   PMID:26571351   PMID:26578769   PMID:26587832   PMID:26596834   PMID:26613553  
PMID:26633084   PMID:26646591   PMID:26684442   PMID:26719551   PMID:26739946   PMID:26771271   PMID:26774659   PMID:26803058   PMID:26880163   PMID:26888112   PMID:26922685   PMID:26994621  
PMID:27029682   PMID:27153462   PMID:27169346   PMID:27226565   PMID:27330078   PMID:27338803   PMID:27342779   PMID:27362234   PMID:27385593   PMID:27400929   PMID:27421901   PMID:27450915  
PMID:27481942   PMID:27485115   PMID:27587791   PMID:27632347   PMID:27701011   PMID:27703221   PMID:27887991   PMID:27900465   PMID:27993566   PMID:28024151   PMID:28093224   PMID:28165045  
PMID:28235084   PMID:28262783   PMID:28275305   PMID:28287890   PMID:28298427   PMID:28300321   PMID:28327457   PMID:28442571   PMID:28467637   PMID:28476886   PMID:28506092   PMID:28557859  
PMID:28569760   PMID:28607487   PMID:28634209   PMID:28692628   PMID:28733084   PMID:28753063   PMID:28756611   PMID:28813418   PMID:28824322   PMID:28860381   PMID:28933308   PMID:29061864  
PMID:29132297   PMID:29138797   PMID:29197114   PMID:29255305   PMID:29257221   PMID:29262264   PMID:29331538   PMID:29335412   PMID:29371726   PMID:29404926   PMID:29424570   PMID:29507755  
PMID:29535353   PMID:29581292   PMID:29588580   PMID:29620176   PMID:29670675   PMID:29703608   PMID:29757443   PMID:30069878   PMID:30131371   PMID:30157263   PMID:30172948   PMID:30178312  
PMID:30267546   PMID:30423370   PMID:30468638   PMID:30591486   PMID:30600959   PMID:30668166   PMID:30862702   PMID:30953343   PMID:31023336   PMID:31068382   PMID:31104300   PMID:31115019  
PMID:31142730   PMID:31264537   PMID:31285095   PMID:31290053   PMID:31356401   PMID:31364142   PMID:31395667   PMID:31425733   PMID:31481635   PMID:31604529   PMID:31619245   PMID:31620969  
PMID:31624248   PMID:31685439   PMID:31699066   PMID:31743087   PMID:31786502   PMID:31812970   PMID:31855300   PMID:31915906   PMID:31978323   PMID:32034992   PMID:32101872   PMID:32185627  
PMID:32229175   PMID:32530095   PMID:32624423   PMID:32814053   PMID:32828531   PMID:32918113   PMID:33181690   PMID:33257561   PMID:33356961   PMID:33451866   PMID:33526736   PMID:34090290  


Genomics

Candidate Gene Status
ADRB2 is a candidate Gene for QTL BW456_H
ADRB2 is a candidate Gene for QTL BW455_H
Comparative Map Data
ADRB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5148,826,611 - 148,828,623 (+)EnsemblGRCh38hg38GRCh38
GRCh385148,826,611 - 148,828,623 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375148,206,174 - 148,208,186 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365148,186,349 - 148,188,381 (+)NCBINCBI36hg18NCBI36
Build 345148,186,368 - 148,188,379NCBI
Celera5144,288,206 - 144,290,248 (+)NCBI
Cytogenetic Map5q32NCBI
HuRef5143,352,751 - 143,354,793 (+)NCBIHuRef
CHM1_15147,638,640 - 147,640,684 (+)NCBICHM1_1
Adrb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391862,310,784 - 62,313,052 (-)NCBIGRCm39mm39
GRCm39 Ensembl1862,310,887 - 62,313,030 (-)Ensembl
GRCm381862,177,713 - 62,179,981 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1862,177,816 - 62,179,959 (-)EnsemblGRCm38mm10GRCm38
MGSCv371862,337,470 - 62,339,613 (-)NCBIGRCm37mm9NCBIm37
MGSCv361862,303,185 - 62,305,328 (-)NCBImm8
Celera1863,462,804 - 63,464,949 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1835.1NCBI
Adrb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21855,642,459 - 55,644,501 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1855,502,903 - 55,644,512 (-)Ensembl
Rnor_6.01857,513,792 - 57,515,834 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1857,513,793 - 57,515,834 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01856,739,990 - 56,742,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41858,174,958 - 58,177,000 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11858,247,190 - 58,249,232 (-)NCBI
Celera1853,789,848 - 53,791,890 (-)NCBICelera
RH 3.4 Map18542.9RGD
Cytogenetic Map18q12.1NCBI
Adrb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554155,515,697 - 5,516,980 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554155,515,157 - 5,517,198 (-)NCBIChiLan1.0ChiLan1.0
ADRB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15150,267,321 - 150,269,339 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5150,267,554 - 150,315,892 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05144,259,756 - 144,398,421 (+)NCBIMhudiblu_PPA_v0panPan3
ADRB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1460,048,502 - 60,050,447 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl459,941,517 - 60,050,298 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha459,812,943 - 59,814,888 (-)NCBI
ROS_Cfam_1.0460,537,283 - 60,539,228 (-)NCBI
UMICH_Zoey_3.1460,317,278 - 60,319,223 (-)NCBI
UNSW_CanFamBas_1.0460,444,286 - 60,446,231 (-)NCBI
UU_Cfam_GSD_1.0460,962,485 - 60,964,430 (-)NCBI
Adrb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213144,411,444 - 144,414,154 (-)NCBI
SpeTri2.0NW_0049365045,985,407 - 5,987,453 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADRB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2150,032,782 - 150,035,591 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12150,032,649 - 150,035,591 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ADRB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12351,445,920 - 51,447,942 (+)NCBI
ChlSab1.1 Ensembl2351,446,154 - 51,447,401 (+)Ensembl
Vero_WHO_p1.0NW_02366603426,307,284 - 26,309,305 (-)NCBI
Adrb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247748,211,723 - 8,215,962 (+)NCBI

Position Markers
RH79898  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,206,371 - 148,206,581UniSTSGRCh37
Build 365148,186,564 - 148,186,774RGDNCBI36
Celera5144,288,421 - 144,288,631RGD
Cytogenetic Map5q31-q32UniSTS
HuRef5143,352,966 - 143,353,176UniSTS
GDB:294209  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,207,675 - 148,207,961UniSTSGRCh37
Build 365148,187,868 - 148,188,154RGDNCBI36
Celera5144,289,726 - 144,290,012RGD
Cytogenetic Map5q31-q32UniSTS
HuRef5143,354,271 - 143,354,557UniSTS
GDB:606222  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,206,421 - 148,207,333UniSTSGRCh37
Build 365148,186,614 - 148,187,526RGDNCBI36
Celera5144,288,471 - 144,289,383RGD
Cytogenetic Map5q31-q32UniSTS
HuRef5143,353,016 - 143,353,928UniSTS
GDB:606238  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,206,454 - 148,206,873UniSTSGRCh37
Build 365148,186,647 - 148,187,066RGDNCBI36
Celera5144,288,504 - 144,288,923RGD
Cytogenetic Map5q31-q32UniSTS
HuRef5143,353,049 - 143,353,468UniSTS
GDB:606265  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,206,866 - 148,207,527UniSTSGRCh37
Build 365148,187,059 - 148,187,720RGDNCBI36
Celera5144,288,916 - 144,289,577RGD
Cytogenetic Map5q31-q32UniSTS
HuRef5143,353,461 - 143,354,122UniSTS
ADRB2sts1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,206,811 - 148,207,265UniSTSGRCh37
Build 365148,187,004 - 148,187,458RGDNCBI36
Celera5144,288,861 - 144,289,315RGD
HuRef5143,353,406 - 143,353,860UniSTS
PMC109640P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,207,045 - 148,207,443UniSTSGRCh37
Build 365148,187,238 - 148,187,636RGDNCBI36
Celera5144,289,095 - 144,289,493RGD
Cytogenetic Map5q31-q32UniSTS
HuRef5143,353,640 - 143,354,038UniSTS
PMC115184P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,206,240 - 148,206,576UniSTSGRCh37
Build 365148,186,433 - 148,186,769RGDNCBI36
Celera5144,288,290 - 144,288,626RGD
Cytogenetic Map5q31-q32UniSTS
HuRef5143,352,835 - 143,353,171UniSTS
ADRB2_1263  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,207,612 - 148,208,281UniSTSGRCh37
Build 365148,187,805 - 148,188,474RGDNCBI36
Celera5144,289,662 - 144,290,332RGD
HuRef5143,354,207 - 143,354,877UniSTS
WI-19151  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,207,839 - 148,208,101UniSTSGRCh37
Build 365148,188,032 - 148,188,294RGDNCBI36
Celera5144,289,890 - 144,290,152RGD
Cytogenetic Map5q31-q32UniSTS
HuRef5143,354,435 - 143,354,697UniSTS
GeneMap99-GB4 RH Map5571.96UniSTS
Whitehead-RH Map5486.1UniSTS
NCBI RH Map5891.6UniSTS
ADRB2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,206,521 - 148,207,408UniSTSGRCh37
GRCh375148,207,000 - 148,207,207UniSTSGRCh37
Celera5144,288,571 - 144,289,458UniSTS
Celera5144,289,050 - 144,289,257UniSTS
HuRef5143,353,595 - 143,353,802UniSTS
HuRef5143,353,116 - 143,354,003UniSTS
ADRB2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375148,206,521 - 148,207,408UniSTSGRCh37
GRCh375148,207,000 - 148,207,207UniSTSGRCh37
Celera5144,288,571 - 144,289,458UniSTS
Celera5144,289,050 - 144,289,257UniSTS
HuRef5143,353,595 - 143,353,802UniSTS
HuRef5143,353,116 - 143,354,003UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:275
Count of miRNA genes:221
Interacting mature miRNAs:254
Transcripts:ENST00000305988
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 99 109 85 105 222 81 1885 99 72 52 225 543 37 1 1063 700 3 2
Low 2238 2843 1338 504 1553 368 2407 2062 2989 293 997 975 138 141 2074 1
Below cutoff 77 39 298 12 133 13 60 28 663 73 230 64 14 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_016421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA886615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC011354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF022953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF022954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF022955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF022956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF169225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF202305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF203386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK223025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY011291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY136741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC073856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA440083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA705141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ094845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU332834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC295426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KJ534762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC633338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC633339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC633340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X04827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000305988   ⟹   ENSP00000305372
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5148,826,611 - 148,828,623 (+)Ensembl
RefSeq Acc Id: NM_000024   ⟹   NP_000015
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385148,826,611 - 148,828,623 (+)NCBI
GRCh375148,206,156 - 148,254,628 (+)NCBI
Build 365148,186,349 - 148,188,381 (+)NCBI Archive
HuRef5143,352,751 - 143,354,793 (+)ENTREZGENE
CHM1_15147,638,640 - 147,640,684 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_000015   ⟸   NM_000024
- Sequence:
RefSeq Acc Id: ENSP00000305372   ⟸   ENST00000305988
Protein Domains
G_PROTEIN_RECEP_F1_2

Promoters
RGD ID:6802826
Promoter ID:HG_KWN:51472
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000252189
Position:
Human AssemblyChrPosition (strand)Source
Build 365148,186,009 - 148,186,509 (+)MPROMDB
RGD ID:6850194
Promoter ID:EP25039
Type:multiple initiation site
Name:HS_ADRB2
Description:beta 2-Adrenergic receptor, ADRB2, ADRB2R or B2AR gene
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 159; Mammalian beta 2-adrenergic receptor
Experiment Methods:Nuclease protection; Primer extension with homologous sequence ladder
Regulation:various tissues; (induced by or strongly expressed in) hydrocortisone
Position:
Human AssemblyChrPosition (strand)Source
Build 365148,186,379 - 148,186,439EPD
RGD ID:6871190
Promoter ID:EPDNEW_H8760
Type:initiation region
Name:ADRB2_1
Description:adrenoceptor beta 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385148,826,623 - 148,826,683EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_000024.5(ADRB2):c.46A>G (p.Arg16Gly) single nucleotide variant Asthma, nocturnal, susceptibility to [RCV000019316]|not provided [RCV000873016] Chr5:148826877 [GRCh38]
Chr5:148206440 [GRCh37]
Chr5:5q32
risk factor|benign
NM_000024.5(ADRB2):c.79C>G (p.Gln27Glu) single nucleotide variant ADRB2 POLYMORPHISM [RCV000033191]|not provided [RCV000873015] Chr5:148826910 [GRCh38]
Chr5:148206473 [GRCh37]
Chr5:5q32
risk factor|benign
NM_000024.5(ADRB2):c.491C>T (p.Thr164Ile) single nucleotide variant Beta-2-adrenoreceptor agonist, reduced response to [RCV000019320] Chr5:148827322 [GRCh38]
Chr5:148206885 [GRCh37]
Chr5:5q32
drug response
ADRB2, -47C-T single nucleotide variant Beta-2-adrenoreceptor agonist, reduced response to [RCV000019321] Chr5:5q32-q34 pathogenic|drug response
GRCh38/hg38 5q23.3-33.2(chr5:130860928-155321811)x3 copy number gain See cases [RCV000051193] Chr5:130860928..155321811 [GRCh38]
Chr5:130196621..154701371 [GRCh37]
Chr5:130224520..154681564 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2
pathogenic
NM_000024.5(ADRB2):c.46= (p.Arg16=) single nucleotide variant salbutamol response - Efficacy [RCV000211205]|salmeterol response - Efficacy [RCV000211334] Chr5:148826877 [GRCh38]
Chr5:148206440 [GRCh37]
Chr5:5q32
drug response
GRCh38/hg38 5q23.3-33.2(chr5:129847794-153353546)x3 copy number gain See cases [RCV000138808] Chr5:129847794..153353546 [GRCh38]
Chr5:129183487..152733106 [GRCh37]
Chr5:129211386..152713299 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh38/hg38 5q31.3-32(chr5:141089988-149530678)x3 copy number gain See cases [RCV000139504] Chr5:141089988..149530678 [GRCh38]
Chr5:140469572..148910241 [GRCh37]
Chr5:140449756..148890434 [NCBI36]
Chr5:5q31.3-32
pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3
likely benign
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Familial adenomatous polyposis 1 [RCV001381154]|Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2
pathogenic
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910)x3 copy number gain See cases [RCV000449349] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3
pathogenic
GRCh37/hg19 5q31.3-32(chr5:141113273-149154835)x1 copy number loss See cases [RCV000510497] Chr5:141113273..149154835 [GRCh37]
Chr5:5q31.3-32
pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
NM_000024.6(ADRB2):c.*34del deletion not provided [RCV001534572] Chr5:148828097 [GRCh38]
Chr5:148207660 [GRCh37]
Chr5:5q32
benign
NM_000024.5(ADRB2):c.771A>T (p.Gly257=) single nucleotide variant not provided [RCV000966605] Chr5:148827602 [GRCh38]
Chr5:148207165 [GRCh37]
Chr5:5q32
likely benign
NM_000024.5(ADRB2):c.990A>C (p.Pro330=) single nucleotide variant not provided [RCV000966817] Chr5:148827821 [GRCh38]
Chr5:148207384 [GRCh37]
Chr5:5q32
likely benign
NM_000024.5(ADRB2):c.560A>G (p.Asn187Ser) single nucleotide variant not provided [RCV000873923] Chr5:148827391 [GRCh38]
Chr5:148206954 [GRCh37]
Chr5:5q32
likely benign
NM_000024.5(ADRB2):c.1179T>C (p.Thr393=) single nucleotide variant not provided [RCV000874253] Chr5:148828010 [GRCh38]
Chr5:148207573 [GRCh37]
Chr5:5q32
benign
NM_000024.5(ADRB2):c.66C>T (p.His22=) single nucleotide variant not provided [RCV000873645] Chr5:148826897 [GRCh38]
Chr5:148206460 [GRCh37]
Chr5:5q32
benign
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32
uncertain significance
NM_000024.5(ADRB2):c.659C>G (p.Ser220Cys) single nucleotide variant not provided [RCV000873803] Chr5:148827490 [GRCh38]
Chr5:148207053 [GRCh37]
Chr5:5q32
benign
GRCh37/hg19 5q31.3-32(chr5:140424333-148985999)x3 copy number gain not provided [RCV000848228] Chr5:140424333..148985999 [GRCh37]
Chr5:5q31.3-32
uncertain significance
NM_000024.5(ADRB2):c.206A>G (p.Asn69Ser) single nucleotide variant not provided [RCV000876878] Chr5:148827037 [GRCh38]
Chr5:148206600 [GRCh37]
Chr5:5q32
benign
NM_000024.5(ADRB2):c.276C>G (p.Ala92=) single nucleotide variant not provided [RCV000923156] Chr5:148827107 [GRCh38]
Chr5:148206670 [GRCh37]
Chr5:5q32
likely benign
NM_000024.5(ADRB2):c.1098T>C (p.Tyr366=) single nucleotide variant not provided [RCV000874830] Chr5:148827929 [GRCh38]
Chr5:148207492 [GRCh37]
Chr5:5q32
benign
NM_000024.5(ADRB2):c.492C>A (p.Thr164=) single nucleotide variant not provided [RCV000935134] Chr5:148827323 [GRCh38]
Chr5:148206886 [GRCh37]
Chr5:5q32
likely benign
Single allele single nucleotide variant not provided [RCV001537123] Chr5:148826178 [GRCh38]
Chr5:148205741 [GRCh37]
Chr5:5q32
benign
NM_000024.6(ADRB2):c.*25_*26insG insertion not provided [RCV001541383] Chr5:148828098..148828099 [GRCh38]
Chr5:148207661..148207662 [GRCh37]
Chr5:5q32
benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:286 AgrOrtholog
COSMIC ADRB2 COSMIC
Ensembl Genes ENSG00000169252 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000305372 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000305988 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000169252 GTEx
HGNC ID HGNC:286 ENTREZGENE
Human Proteome Map ADRB2 Human Proteome Map
InterPro ADR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADRB2_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:154 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 154 ENTREZGENE
OMIM 109690 OMIM
  600807 OMIM
  601665 OMIM
PANTHER PTHR24248:SF21 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ADRB2 RGD, PharmGKB
PRINTS ADRENERGICR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADRENRGCB2AR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2N4T7_HUMAN UniProtKB/TrEMBL
  ADRB2_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q9BYZ0_HUMAN UniProtKB/TrEMBL
  X5DQM5_HUMAN UniProtKB/TrEMBL
UniProt Secondary B0LPE4 UniProtKB/Swiss-Prot
  B2R7X2 UniProtKB/Swiss-Prot
  O14823 UniProtKB/Swiss-Prot
  O14824 UniProtKB/Swiss-Prot
  O14825 UniProtKB/Swiss-Prot
  O14826 UniProtKB/Swiss-Prot
  Q4JG18 UniProtKB/Swiss-Prot
  Q53GA6 UniProtKB/Swiss-Prot
  Q6GMT4 UniProtKB/Swiss-Prot
  Q6P4D8 UniProtKB/Swiss-Prot
  Q8NEQ9 UniProtKB/Swiss-Prot
  Q96EC3 UniProtKB/Swiss-Prot
  Q9UCZ0 UniProtKB/Swiss-Prot
  Q9UCZ1 UniProtKB/Swiss-Prot
  Q9UCZ2 UniProtKB/Swiss-Prot
  Q9UCZ3 UniProtKB/Swiss-Prot
  Q9UH95 UniProtKB/Swiss-Prot
  Q9UHA1 UniProtKB/Swiss-Prot
  Q9UMZ5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-01 ADRB2  adrenoceptor beta 2  ADRB2  adrenoceptor beta 2, surface  Symbol and/or name change 5135510 APPROVED
2015-12-01 ADRB2  adrenoceptor beta 2    adrenoceptor beta 2, surface  Symbol and/or name change 5135510 APPROVED
2012-05-15 ADRB2  adrenoceptor beta 2, surface  ADRB2  adrenergic, beta-2-, receptor, surface  Symbol and/or name change 5135510 APPROVED
2011-08-16 ADRB2  adrenergic, beta-2-, receptor, surface  ADRB2  adrenergic, beta-2-, receptor, surface  Symbol and/or name change 5135510 APPROVED