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Gene: ADM (adrenomedullin) Homo sapiens
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Symbol: ADM
Name: adrenomedullin
Description: Exhibits adrenomedullin receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; defense response to bacterium; and regulation of blood circulation. Localizes to cytoplasm and extracellular space. Implicated in brain infarction; breast cancer; pancreatic cancer; and pulmonary hypertension. Biomarker of several diseases, including artery disease (multiple); diabetic retinopathy; glucose metabolism disease (multiple); insulinoma; and obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AM; PAMP; preproadrenomedullin; proadrenomedullin N-20 terminal peptide
Orthologs:
Mus musculus (house mouse) : Adm (adrenomedullin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adm (adrenomedullin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adm (adrenomedullin)
Pan paniscus (bonobo/pygmy chimpanzee) : ADM (adrenomedullin)
Canis lupus familiaris (dog) : ADM (adrenomedullin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adm (adrenomedullin)
Sus scrofa (pig) : ADM (adrenomedullin)
Chlorocebus sabaeus (African green monkey) : ADM (adrenomedullin)
Heterocephalus glaber (naked mole-rat) : Adm (adrenomedullin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1110,305,073 - 10,307,397 (+)EnsemblGRCh38hg38GRCh38
GRCh381110,305,073 - 10,307,397 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371110,326,642 - 10,328,923 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361110,283,218 - 10,285,499 (+)NCBINCBI36hg18NCBI36
Build 341110,283,217 - 10,285,499NCBI
Celera1110,448,490 - 10,450,771 (+)NCBI
Cytogenetic Map11p15.4NCBI
HuRef119,999,508 - 10,001,789 (+)NCBIHuRef
CHM1_11110,324,643 - 10,327,066 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ADM
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730917
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-05-19
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.