MYC (MYC proto-oncogene, bHLH transcription factor) - Rat Genome Database

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Gene: MYC (MYC proto-oncogene, bHLH transcription factor) Homo sapiens
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Symbol: MYC
Name: MYC proto-oncogene, bHLH transcription factor
RGD ID: 731438
HGNC Page HGNC:7553
Description: Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; SCF ubiquitin ligase complex binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including positive regulation of macromolecule metabolic process; regulation of DNA-templated transcription; and regulation of fibroblast proliferation. Acts upstream of with a positive effect on negative regulation of gene expression via chromosomal CpG island methylation. Acts upstream of or within positive regulation of cell population proliferation and regulation of gene expression. Located in chromatin; nucleus; and rough endoplasmic reticulum. Part of Myc-Max complex and RNA polymerase II transcription repressor complex. Implicated in several diseases, including angiosarcoma; demyelinating disease; hematologic cancer (multiple); lung adenocarcinoma; and prostate cancer (multiple). Biomarker of several diseases, including hepatitis C; leukemia (multiple); liver disease (multiple); polycystic kidney disease 1; and urinary system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: avian myelocytomatosis viral oncogene homolog; bHLHe39; c-Myc; class E basic helix-loop-helix protein 39; cMyc; MRTL; myc proto-oncogene protein; myc-related translation/localization regulatory factor; MYCC; proto-oncogene c-Myc; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Candidate Gene For: PRSTS2_H PRSTS136_H PRSTS140_H PRSTS139_H PRSTS141_H PRSTS137_H PRSTS138_H PRSTS135_H
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388127,735,434 - 127,742,951 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8127,735,434 - 127,742,951 (+)EnsemblGRCh38hg38GRCh38
GRCh378128,747,680 - 128,755,197 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368128,817,498 - 128,822,856 (+)NCBINCBI36Build 36hg18NCBI36
Build 348128,817,685 - 128,822,853NCBI
Celera8124,928,812 - 124,934,177 (+)NCBICelera
Cytogenetic Map8q24.21NCBI
HuRef8124,069,829 - 124,075,195 (+)NCBIHuRef
CHM1_18128,788,551 - 128,793,916 (+)NCBICHM1_1
T2T-CHM13v2.08128,862,888 - 128,870,405 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Aberrant Crypt Foci  (ISO)
acute kidney failure  (ISO)
acute lymphoblastic leukemia  (IEP)
acute myeloid leukemia  (EXP)
acute promyelocytic leukemia  (IEP,IMP)
adenocarcinoma  (EXP)
Alcoholic Liver Diseases  (IEP,ISO)
angiosarcoma  (EXP,IAGP)
Animal Disease Models  (EXP)
atherosclerosis  (ISO)
autosomal dominant polycystic kidney disease  (EXP,ISO,ISS)
autosomal recessive polycystic kidney disease  (ISO)
B-lymphoblastic leukemia/lymphoma  (ISO)
breast cancer  (IAGP,ISO,ISS)
Breast Neoplasms  (ISO)
Burkitt lymphoma  (EXP,IAGP,ISS)
carcinoma  (EXP)
Cardiomegaly  (ISO)
Carotid Artery Injuries  (ISO)
cholesteatoma of middle ear  (IAGP)
Chromosome Breakage  (EXP)
chronic lymphocytic leukemia  (IEP)
clear cell renal cell carcinoma  (IEP)
cleft lip  (EXP)
cleft palate  (EXP)
Colonic Neoplasms  (EXP,ISO)
Colorectal Neoplasms  (EXP)
coronary restenosis  (ISO)
COVID-19  (HEP)
demyelinating disease  (IAGP)
diffuse large B-cell lymphoma  (EXP)
disease of cellular proliferation  (EXP,IAGP)
Disease Progression  (EXP)
Ductal Carcinoma  (EXP)
Endometrial Neoplasms  (EXP)
esophageal carcinoma  (IAGP)
Esophageal Neoplasms  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (EXP)
Experimental Liver Neoplasms  (EXP,ISO)
Experimental Mammary Neoplasms  (ISO)
glioblastoma  (EXP)
Hemorrhagic Shock  (ISO)
hepatitis C  (IEP)
hepatocellular carcinoma  (EXP,IEP,ISO,ISS)
Hodgkin's lymphoma  (IAGP)
hyperparathyroidism  (IEP)
hypertrophic cardiomyopathy  (EXP)
Kidney Reperfusion Injury  (ISO)
Left Ventricular Hypertrophy  (EXP)
leiomyoma  (ISO)
liver cirrhosis  (IEP)
Liver Injury  (ISO)
Liver Neoplasms  (EXP)
lung adenocarcinoma  (EXP,IAGP,IDA)
lung cancer  (IEP)
Lung Neoplasms  (EXP)
lung non-small cell carcinoma  (EXP)
Lung Reperfusion Injury  (ISO)
lung small cell carcinoma  (ISO)
medulloblastoma  (EXP)
Merkel cell carcinoma  (EXP)
myelodysplastic syndrome  (EXP)
Neoplasm Metastasis  (EXP)
Neoplastic Cell Transformation  (EXP)
nephroblastoma  (IEP,ISO)
neuroblastoma  (EXP,IAGP)
neuroectodermal tumor  (EXP)
non-Hodgkin lymphoma  (IAGP)
obesity  (ISO)
osteoporosis  (ISO)
osteosarcoma  (EXP)
Ovarian Neoplasms  (EXP)
pancreatic cancer  (EXP,ISO)
pancreatic carcinoma  (ISS)
papillary thyroid carcinoma  (IEP)
polycystic kidney disease  (ISO)
polycystic kidney disease 1  (IEP,ISO)
primary ovarian insufficiency  (IAGP)
prolactinoma  (ISO)
prostate adenocarcinoma  (IMP)
prostate cancer  (IAGP,IEP)
prostate carcinoma in situ  (ISO)
prostatic hypertrophy  (ISO)
Prostatic Neoplasms  (EXP)
pulmonary hypertension  (ISO)
renal cell carcinoma  (IEP,ISO)
renal fibrosis  (ISO)
rhabdoid cancer  (IEP)
skin melanoma  (IAGP)
Sporadic Papillary Renal Cell Carcinoma  (IEP)
squamous cell carcinoma  (EXP)
steatotic liver disease  (EXP)
Stomach Neoplasms  (EXP)
thyroid cancer  (ISO)
Transplant Rejection  (ISO)
trichorhinophalangeal syndrome type I  (IAGP)
urinary bladder cancer  (EXP,IAGP,IEP,ISO)
Uterine Cervical Neoplasms  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (ISO)
(+)-schisandrin B  (ISO)
(-)-anisomycin  (EXP)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-selegiline  (EXP)
(1->4)-beta-D-glucan  (ISO)
(20S)-ginsenoside Rg3  (EXP)
(25R)-cholest-5-ene-3beta,26-diol  (EXP)
(R)-lipoic acid  (EXP)
(R)-noradrenaline  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-colchicine  (ISO)
(S)-nicotine  (EXP,ISO)
1'-acetoxychavicol acetate  (EXP)
1,1-dichloroethene  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dichlorobenzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-benzothiazole-2-thiol  (EXP)
1,4-dichlorobenzene  (ISO)
1,8-cineole  (EXP)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (ISO)
1-nitropyrene  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
1D-myo-inositol 1,4,5-trisphosphate  (ISO)
2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-D  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-butoxyethanol  (ISO)
2-hydroxy-17beta-estradiol  (EXP)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (EXP)
2-hydroxypropanoic acid  (EXP)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (ISO)
2-nitrofluorene  (ISO)
2-nitrotoluene  (ISO)
2-palmitoylglycerol  (EXP)
26-hydroxycholesterol  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3'-diindolylmethane  (EXP,ISO)
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol  (ISO)
3-aminobenzamide  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenylprop-2-enal  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP,ISO)
4-hydroxy-17beta-estradiol  (EXP)
4-Hydroxy-N-desmethyltamoxifen  (EXP)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (EXP)
5-bromo-2'-deoxyuridine  (ISO)
5-fluorouracil  (EXP,ISO)
5-nitroso-8-quinolinol  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7beta-aminocephalosporanic acid  (EXP)
8-Br-cAMP  (EXP)
8-bromo-3',5'-cyclic GMP  (EXP)
abexinostat  (EXP)
acetaldehyde  (ISO)
acetohydrazide  (ISO)
acetylleucyl-leucyl-norleucinal  (EXP)
acetylsalicylic acid  (EXP,ISO)
aconitine  (EXP,ISO)
acrolein  (EXP,ISO)
acrylamide  (EXP)
actinomycin D  (EXP,ISO)
adenosine  (EXP)
Aeroplysinin 1  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
AH23848  (EXP)
alachlor  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP)
allethrin  (EXP)
alpha-hexachlorocyclohexane  (ISO)
alpha-naphthoflavone  (EXP,ISO)
alpha-pinene  (EXP)
alpha-Zearalanol  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amifostine  (EXP)
amiodarone  (ISO)
ammonium chloride  (ISO)
ammonium hexachloroplatinate  (EXP)
amsacrine  (EXP)
andrographolide  (EXP)
androstane  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antimycin A  (EXP)
antirheumatic drug  (EXP)
Antrocin  (EXP)
aprepitant  (EXP)
aristolochic acid A  (EXP)
aristolochic acids  (ISO)
arsenic acid  (EXP,ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
ARV-825  (EXP)
Asimicin  (ISO)
aspartame  (EXP,ISO)
atorvastatin calcium  (EXP)
atrazine  (EXP)
Azaspiracid  (EXP)
bathocuproine disulfonic acid  (EXP)
benazepril  (ISO)
benzamide  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP,ISO)
Benzo[b]fluorene  (ISO)
benzoates  (EXP)
benzoic acid  (EXP)
benzylpenicillin  (ISO)
berberine  (ISO)
beryllium difluoride  (ISO)
beryllium sulfate  (ISO)
betulin  (EXP)
betulinic acid  (EXP)
bicalutamide  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (EXP)
bisphenol F  (EXP,ISO)
bleomycin A2  (ISO)
bleomycin A5  (EXP)
bortezomib  (EXP)
bromobenzene  (ISO)
bromochloroacetic acid  (ISO)
bromodichloromethane  (ISO)
bromoform  (ISO)
bucladesine  (EXP)
budesonide  (ISO)
bufalin  (EXP)
busulfan  (EXP)
Butylbenzyl phthalate  (EXP)
Butylparaben  (EXP)
butyric acid  (EXP,ISO)
C.I. Natural Red 20  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (EXP)
caffeine  (EXP,ISO)
calcein am  (EXP)
calcitriol  (EXP)
calcium dichloride  (ISO)
calmidazolium  (ISO)
camptothecin  (EXP)
cannabidiol  (EXP,ISO)
capsaicin  (EXP)
captan  (ISO)
carbamazepine  (EXP)
carbofuran  (EXP,ISO)
carbon nanotube  (EXP,ISO)
carbonyl sulfide  (ISO)
carboplatin  (EXP)
carboxy-PTIO  (EXP)
carvedilol  (ISO)
catechol  (EXP)
celastrol  (EXP,ISO)
celecoxib  (EXP)
CGP 52608  (EXP)
chalcone  (EXP)
chelerythrine  (EXP)
CHIR 99021  (EXP)
chlorambucil  (EXP)
Chlorodibromomethane  (ISO)
chloroform  (ISO)
chlorohydrocarbon  (EXP)
chloropicrin  (EXP)
chlorpromazine  (EXP)
chlorpyrifos  (EXP,ISO)
Cholestane-3,5,6-triol  (ISO)
choline  (ISO)
chromium(6+)  (EXP,ISO)
ciglitazone  (EXP)
ciguatoxin CTX1B  (ISO)
cilostazol  (EXP)
Cinobufagin  (EXP)
cisplatin  (EXP,ISO)
clofarabine  (EXP)
clofibrate  (EXP,ISO)
clotrimazole  (EXP)
cobalt dichloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cordycepin  (EXP)
coumarin  (EXP)
coumestrol  (EXP)
crocidolite asbestos  (EXP,ISO)
crocin-1  (EXP)
CU-O LINKAGE  (EXP)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
cyanamide  (ISO)
cycloheximide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyproterone acetate  (ISO)
D-glucose  (EXP,ISO)
daidzein  (EXP)
DDE  (EXP)
DDT  (EXP,ISO)
deguelin  (EXP,ISO)
deoxynivalenol  (EXP)
desferrioxamine B  (EXP)
Destruxin B  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP,ISO)
diarylheptanoid  (EXP)
diazinon  (ISO)
dibenziodolium  (EXP)
dibenzoylmethane  (EXP)
dibromoacetic acid  (ISO)
Dibromoacetonitrile  (ISO)
Dibutyl phosphate  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (EXP,ISO)
dicrotophos  (EXP)
Dictamnine  (EXP)
dieldrin  (ISO)
diethylstilbestrol  (EXP,ISO)
dihydroartemisinin  (EXP)
Dimaprit  (EXP)
dimethyl sulfoxide  (EXP)
dimethylarsinic acid  (EXP)
diminazene diaceturate  (EXP)
dinaciclib  (EXP)
diosgenin  (EXP)
dioxygen  (EXP,ISO)
diquat  (ISO)
disodium selenite  (EXP,ISO)
disulfiram  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
elemental selenium  (EXP,ISO)
emodin  (ISO)
endosulfan  (EXP,ISO)
enzalutamide  (EXP,ISO)
epichlorohydrin  (EXP)
epoxiconazole  (ISO)
erlotinib hydrochloride  (EXP)
erythromycin estolate  (ISO)
estra-1,3,5(10)-triene-3,16beta-diol  (ISO)
estriol  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (EXP)
etoposide  (EXP)
eugenol  (ISO)
everolimus  (EXP)
Evodiamine  (EXP)
fenofibrate  (ISO)
fenthion  (EXP)
fipronil  (ISO)
fluoranthene  (ISO)
fluoxetine  (EXP)
flusilazole  (ISO)
flutamide  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
FR900359  (EXP)
fructose  (EXP)
fucoidan  (EXP)
fulvestrant  (EXP,ISO)
furan  (ISO)
galangin  (ISO)
gallium nitrate  (EXP)
gamma-aminobutyric acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gamma-linolenic acid  (EXP)
gamma-tocopherol  (ISO)
gefitinib  (EXP)
gemcitabine  (EXP,ISO)
gemfibrozil  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
glucaric acid  (ISO)
glucose  (EXP,ISO)
glutathione  (EXP,ISO)
Glutethimide  (ISO)
glycerol  (EXP,ISO)
glycidol  (ISO)
glycine betaine  (ISO)
glyphosate  (EXP,ISO)
guanosine  (EXP)
guggulsterone  (EXP)
GW 4064  (EXP)
GW 7647  (ISO)
harmine  (EXP)
hemin  (EXP)
heparin  (EXP,ISO)
hesperetin  (ISO)
hexachlorophene  (EXP)
hexadecanoic acid  (ISO)
hexamethylene diisocyanate  (EXP)
hexanal  (EXP)
Honokiol  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (EXP)
hydroxamic acid  (EXP)
Indeno[1,2,3-cd]pyrene  (EXP)
indirubin  (ISO)
indole-3-methanol  (ISO)
indometacin  (EXP,ISO)
inulin  (ISO)
ionomycin  (EXP)
iron atom  (EXP)
iron(0)  (EXP)
iron(III) nitrilotriacetate  (ISO)
isoprenaline  (ISO)
ketamine  (ISO)
KT 5823  (EXP)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead nitrate  (ISO)
leflunomide  (EXP)
letrozole  (EXP)
limonene  (ISO)
linalool  (EXP)
linuron  (ISO)
lipoic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
lithium chloride  (EXP,ISO)
Lobetyolin  (EXP)
losartan  (ISO)
lupeol  (ISO)
LY294002  (EXP)
m-xylene  (ISO)
mancozeb  (ISO)
maneb  (ISO)
masoprocol  (EXP)
mebendazole  (EXP)
melatonin  (EXP)
meloxicam  (EXP)
memantine  (EXP)
menadione  (EXP)
mercury atom  (EXP,ISO)
mercury dichloride  (ISO)
mercury(0)  (EXP,ISO)
meso-tetrakis(N-methyl-4-pyridyl)porphine(4+)  (EXP)
mestranol  (ISO)
metformin  (EXP,ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methotrexate  (EXP,ISO)
methoxyacetic acid  (EXP)
methyl methanesulfonate  (EXP)
methylarsonic acid  (EXP)
methylmercury chloride  (EXP,ISO)
methylseleninic acid  (EXP)
metoprolol  (ISO)
microcystin-LR  (EXP,ISO)
mifepristone  (EXP,ISO)
mitoxantrone  (EXP)
ML-7  (EXP)
molibresib  (EXP)
monensin A  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
myricetin  (EXP)
N(4)-hydroxycytidine  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N,N-bis(2-hydroxypropyl)nitrosamine  (ISO)
N,N-dimethylaniline  (EXP)
N-(6-acetamidohexyl)acetamide  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-methylnicotinate  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nafenopin  (ISO)
naloxone  (ISO)
naphthalene  (ISO)
naphthalenes  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel subsulfide  (EXP)
nickel sulfate  (EXP,ISO)
niclosamide  (EXP,ISO)
nicotinamide  (ISO)
nicotine  (EXP,ISO)
nifedipine  (EXP)
nirogacestat  (EXP)
nitrofurazone  (ISO)
nitroprusside  (EXP)
Nodularin  (EXP)
NS-398  (EXP)
o-anisidine  (EXP)
obeticholic acid  (EXP)
ochratoxin A  (EXP,ISO)
okadaic acid  (EXP)
oleanolic acid  (EXP,ISO)
oridonin  (EXP)
ortho-Aminoazotoluene  (ISO)
ouabain  (EXP)
oxaliplatin  (EXP)
oxidopamine  (ISO)
ozone  (EXP,ISO)
paclitaxel  (EXP,ISO)
palbociclib  (EXP)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PD 0325901  (EXP)
Pentoxifylline  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
pevonedistat  (EXP)
phenethyl isothiocyanate  (EXP)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
phenol  (EXP)
phenylhydrazine  (ISO)
phenytoin  (EXP,ISO)
PhIP  (EXP,ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phorone  (ISO)
phosgene  (ISO)
picene  (EXP)
pinosylvin  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
platycodin D  (EXP)
poly(I:C)  (EXP)
ponatinib  (EXP)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
proanthocyanidin  (EXP)
progesterone  (EXP,ISO)
promegestone  (EXP)
promethazine  (ISO)
propiconazole  (ISO)
propylparaben  (EXP)
prostaglandin D2  (ISO)
prostaglandin E2  (EXP,ISO)
pterostilbene  (EXP)
puerarin  (EXP)
putrescine  (ISO)
pyrrolidine dithiocarbamate  (EXP)
pyrvinium  (EXP)
quartz  (EXP)
quercetin  (EXP)
quinacrine  (EXP)
quinapril hydrochloride  (ISO)
quinidine  (ISO)
quinolone  (EXP)
quizartinib  (EXP)
rac-lactic acid  (EXP)
raloxifene  (EXP)
ranitidine  (ISO)
reactive oxygen species  (EXP)
Rebamipide  (ISO)
reserpine  (EXP,ISO)
resveratrol  (EXP,ISO)
ribavirin  (EXP)
riboflavin  (EXP)
ritonavir  (EXP)
rotenone  (ISO)
royal jelly  (ISO)
ruxolitinib  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
saccharin  (ISO)
Salinomycin  (EXP)
salvianolic acid B  (ISO)
sapanisertib  (EXP)
SB 431542  (EXP)
Securinine  (EXP)
selenium atom  (EXP,ISO)
selinexor  (EXP)
selumetinib  (ISO)
serpentine asbestos  (EXP)
sertraline  (EXP)
sevoflurane  (EXP)
Shikonin  (EXP)
sildenafil citrate  (ISO)
silibinin  (EXP)
silicon dioxide  (EXP)
sirolimus  (EXP)
sirtinol  (ISO)
sodium arsenite  (EXP,ISO)
sodium chromate  (EXP)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
Soman  (ISO)
sorafenib  (EXP)
staurosporine  (EXP)
styrene oxide  (EXP)
SU6656  (EXP)
succimer  (ISO)
succinic acid  (EXP)
sulfates  (EXP)
sulforaphane  (ISO)
sulfur dioxide  (ISO)
sulindac  (EXP,ISO)
sunitinib  (EXP)
T-2 toxin  (ISO)
tacrolimus hydrate  (ISO)
tadalafil  (ISO)
taiwanin C  (EXP)
tamibarotene  (EXP)
tamoxifen  (EXP,ISO)
Tanshinone I  (EXP,ISO)
taurocholic acid  (EXP,ISO)
tebufenpyrad  (EXP)
temozolomide  (EXP)
teniposide  (EXP)
terbufos  (EXP)
terbutylazine  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (EXP,ISO)
Tetrachlorobisphenol A  (EXP,ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thapsigargin  (EXP)
theaflavin  (ISO)
theophylline  (EXP,ISO)
thiamine(1+) chloride  (ISO)
thifluzamide  (EXP)
thioacetamide  (ISO)
thiophenes  (EXP)
thiram  (EXP)
thymidine  (EXP)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
thymoquinone  (EXP)
tiazofurine  (EXP)
titanium dioxide  (EXP,ISO)
tocopherol  (ISO)
toxaphene  (ISO)
trametinib  (EXP)
trans-chalcone  (EXP)
trans-pinosylvin  (EXP)
Tributyltin oxide  (EXP)
trichloroacetic acid  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP,ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (EXP,ISO)
troglitazone  (EXP)
trovafloxacin  (ISO)
tubastatin A  (EXP)
tunicamycin  (EXP)
undecane  (ISO)
urethane  (EXP,ISO)
uridine  (EXP)
valproic acid  (EXP,ISO)
vemurafenib  (EXP)
venetoclax  (EXP)
vincaleukoblastine  (EXP,ISO)
vincristine  (EXP,ISO)
vinyl carbamate  (ISO)
vorinostat  (EXP,ISO)
WIN 55212-2  (ISO)
wortmannin  (EXP,ISO)
WR-1065  (EXP)
xanthohumol  (ISO)
zearalenone  (EXP,ISO)
zerumbone  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acinar cell proliferation  (ISO)
amino acid transport  (ISO)
B cell apoptotic process  (ISO)
branching involved in ureteric bud morphogenesis  (ISS)
cell population proliferation  (ISO)
cellular response to angiotensin  (ISO)
cellular response to arsenite(3-)  (ISO)
cellular response to carbohydrate stimulus  (ISO)
cellular response to cycloheximide  (ISO)
cellular response to cytokine stimulus  (ISO)
cellular response to dimethyl sulfoxide  (ISO)
cellular response to endothelin  (ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to estrogen stimulus  (ISO)
cellular response to fibroblast growth factor stimulus  (ISO)
cellular response to growth hormone stimulus  (ISO)
cellular response to hydrostatic pressure  (ISO)
cellular response to hypoxia  (IDA)
cellular response to insulin stimulus  (ISO)
cellular response to interferon-alpha  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to lectin  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to phorbol 13-acetate 12-myristate  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
cellular response to prolactin  (ISO)
cellular response to putrescine  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to testosterone stimulus  (ISO)
cellular response to type II interferon  (ISO)
cellular response to UV  (IEP)
cellular response to xenobiotic stimulus  (IDA,ISO)
chromatin remodeling  (IDA)
chromosome organization  (IDA)
detection of mechanical stimulus involved in sensory perception of sound  (ISO)
DNA damage response  (IDA,ISO)
DNA-templated transcription  (ISO)
DNA-templated transcription initiation  (ISO)
ERK1 and ERK2 cascade  (IDA)
fibroblast apoptotic process  (TAS)
G0 to G1 transition  (ISO)
G1/S transition of mitotic cell cycle  (IDA)
glucose metabolic process  (ISO)
hypothalamus development  (ISO)
in utero embryonic development  (ISO)
inner mitochondrial membrane organization  (ISO)
intracellular iron ion homeostasis  (IDA)
intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
lactic acid secretion  (ISO)
liver regeneration  (ISO)
MAPK cascade  (IMP)
middle ear morphogenesis  (ISO)
myoblast proliferation  (ISO)
myotube differentiation  (ISO)
negative regulation of apoptotic process  (ISS)
negative regulation of cell division  (IDA)
negative regulation of D-glucose import  (ISO)
negative regulation of epithelial cell apoptotic process  (ISO)
negative regulation of fibroblast proliferation  (IDA)
negative regulation of gene expression  (ISO)
negative regulation of gene expression via chromosomal CpG island methylation  (IMP)
negative regulation of monocyte differentiation  (IMP)
negative regulation of stress-activated MAPK cascade  (ISS)
negative regulation of transcription by RNA polymerase II  (IDA,IMP,ISO)
negative regulation of transcription initiation by RNA polymerase II  (IDA)
NK T cell proliferation  (ISO)
ovarian follicle development  (ISO)
pigmentation  (ISO)
positive regulation of acinar cell proliferation  (ISO)
positive regulation of apoptotic signaling pathway  (ISO)
positive regulation of ATP biosynthetic process  (ISO)
positive regulation of B cell apoptotic process  (ISO)
positive regulation of catalytic activity  (ISO)
positive regulation of cell cycle  (ISO)
positive regulation of cell population proliferation  (IBA,IDA,ISO)
positive regulation of cellular respiration  (ISO)
positive regulation of cysteine-type endopeptidase activity  (IDA,ISO)
positive regulation of DNA binding  (ISO)
positive regulation of DNA-templated transcription  (IDA)
positive regulation of epithelial cell proliferation  (IDA)
positive regulation of fibroblast proliferation  (IDA,IMP,ISO)
positive regulation of gene expression  (IDA,IGI)
positive regulation of glial cell proliferation  (ISO)
positive regulation of glycolytic process  (ISO)
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator  (IDA)
positive regulation of mesenchymal cell proliferation  (ISS)
positive regulation of metanephric cap mesenchymal cell proliferation  (ISS)
positive regulation of miRNA transcription  (IDA)
positive regulation of mitochondrial membrane potential  (ISO)
positive regulation of oxidative phosphorylation  (ISO)
positive regulation of smooth muscle cell migration  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of telomere maintenance  (ISS)
positive regulation of transcription by RNA polymerase II  (IDA,IMP,ISO,ISS)
positive regulation of transcription initiation by RNA polymerase II  (ISO)
positive regulation of translation  (NAS)
protein processing  (ISO)
protein-DNA complex disassembly  (IDA)
pyruvate transport  (ISO)
re-entry into mitotic cell cycle  (ISO)
regulation of apoptotic process  (ISO)
regulation of cell cycle process  (IDA)
regulation of DNA-templated transcription  (IEA,ISO,NAS)
regulation of gene expression  (IDA)
regulation of mitotic cell cycle  (ISO)
regulation of oxidative phosphorylation  (ISO)
regulation of somatic stem cell population maintenance  (ISS)
regulation of telomere maintenance  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
response to alkaloid  (ISO)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to gamma radiation  (IDA)
response to growth factor  (TAS)
response to human chorionic gonadotropin  (ISO)
response to radiation  (ISO)
response to xenobiotic stimulus  (IEP)
rRNA metabolic process  (IMP)
skeletal muscle cell differentiation  (ISO)
skeletal system morphogenesis  (ISO)
transcription by RNA polymerase II  (ISO)
transformation of host cell by virus  (ISO)
Wnt signaling pathway  (ISO)

Cellular Component

References

References - curated
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48. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
49. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
50. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
51. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
52. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
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69. Pim1 kinase synergizes with c-MYC to induce advanced prostate carcinoma. Wang J, etal., Oncogene. 2010 Apr 29;29(17):2477-87. doi: 10.1038/onc.2010.10. Epub 2010 Feb 8.
70. Inhibitory effects of lupeal acetate of Cortex periplocae on N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. Wang L, etal., Oncol Lett. 2012 Aug;4(2):231-236. Epub 2012 May 16.
71. Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing. Wen W, etal., Cell Discov. 2020 May 4;6:31. doi: 10.1038/s41421-020-0168-9. eCollection 2020.
72. New prognostic markers revealed by evaluation of genes correlated with clinical parameters in Wilms tumors. Wittmann S, etal., Genes Chromosomes Cancer. 2008 May;47(5):386-95. doi: 10.1002/gcc.20544.
73. The effect of 2,3,4',5-tetrahydroxystilbene-2-0-beta-D glucoside on neointima formation in a rat artery balloon injury model and its possible mechanisms. Xu XL, etal., Eur J Pharmacol. 2013 Jan 5;698(1-3):370-8. doi: 10.1016/j.ejphar.2012.11.019. Epub 2012 Nov 21.
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PMID:31142360   PMID:31142587   PMID:31152129   PMID:31155734   PMID:31164413   PMID:31171361   PMID:31173259   PMID:31175057   PMID:31212712   PMID:31221783   PMID:31229266   PMID:31248836  
PMID:31257571   PMID:31259656   PMID:31262163   PMID:31262817   PMID:31264378   PMID:31266538   PMID:31266772   PMID:31266951   PMID:31271881   PMID:31284776   PMID:31285543   PMID:31292158  
PMID:31296583   PMID:31298382   PMID:31300448   PMID:31300834   PMID:31309249   PMID:31315646   PMID:31321444   PMID:31326549   PMID:31332168   PMID:31348551   PMID:31350286   PMID:31357093  
PMID:31361039   PMID:31375671   PMID:31385458   PMID:31391242   PMID:31391552   PMID:31397502   PMID:31399522   PMID:31402220   PMID:31410206   PMID:31415393   PMID:31416966   PMID:31431461  
PMID:31432128   PMID:31432134   PMID:31439946   PMID:31447321   PMID:31462708   PMID:31467179   PMID:31488218   PMID:31498031   PMID:31501275   PMID:31501481   PMID:31511647   PMID:31519704  
PMID:31541338   PMID:31549316   PMID:31557193   PMID:31560094   PMID:31566109   PMID:31569395   PMID:31582185   PMID:31591389   PMID:31591481   PMID:31595558   PMID:31604907   PMID:31623618  
PMID:31638140   PMID:31648989   PMID:31662451   PMID:31677785   PMID:31677796   PMID:31685988   PMID:31686052   PMID:31690832   PMID:31694914   PMID:31701767   PMID:31703161   PMID:31706988  
PMID:31709636   PMID:31715291   PMID:31718704   PMID:31727874   PMID:31734356   PMID:31739577   PMID:31740732   PMID:31744448   PMID:31751121   PMID:31753913   PMID:31763993   PMID:31767764  
PMID:31771040   PMID:31776900   PMID:31784729   PMID:31790145   PMID:31792212   PMID:31804603   PMID:31815296   PMID:31820036   PMID:31833571   PMID:31844144   PMID:31862696   PMID:31870116  
PMID:31870402   PMID:31874204   PMID:31886177   PMID:31888761   PMID:31894125   PMID:31894338   PMID:31894346   PMID:31930333   PMID:31932576   PMID:31932969   PMID:31933479   PMID:31941709  
PMID:31941754   PMID:31944568   PMID:31960388   PMID:31960591   PMID:31983137   PMID:31990416   PMID:31991488   PMID:31999378   PMID:32001555   PMID:32011831   PMID:32021252   PMID:32029551  
PMID:32047362   PMID:32053284   PMID:32054096   PMID:32059763   PMID:32071334   PMID:32071436   PMID:32074595   PMID:32075881   PMID:32086391   PMID:32094301   PMID:32101329   PMID:32101699  
PMID:32103167   PMID:32115405   PMID:32116112   PMID:32140074   PMID:32145111   PMID:32160543   PMID:32167787   PMID:32179097   PMID:32198408   PMID:32203166   PMID:32222109   PMID:32255563  
PMID:32273477   PMID:32273478   PMID:32275943   PMID:32281291   PMID:32286143   PMID:32296183   PMID:32297641   PMID:32313135   PMID:32316188   PMID:32319562   PMID:32334477   PMID:32345600  
PMID:32350066   PMID:32354864   PMID:32356386   PMID:32373977   PMID:32377743   PMID:32391636   PMID:32410663   PMID:32416067   PMID:32420596   PMID:32432756   PMID:32434218   PMID:32439170  
PMID:32445454   PMID:32453420   PMID:32460013   PMID:32460775   PMID:32462905   PMID:32473656   PMID:32482868   PMID:32497402   PMID:32503978   PMID:32513696   PMID:32517717   PMID:32518154  
PMID:32533239   PMID:32549409   PMID:32549753   PMID:32566654   PMID:32576198   PMID:32581080   PMID:32584426   PMID:32591507   PMID:32592588   PMID:32594835   PMID:32609742   PMID:32611766  
PMID:32627175   PMID:32632092   PMID:32651356   PMID:32659596   PMID:32681068   PMID:32684624   PMID:32685003   PMID:32685545   PMID:32703045   PMID:32705157   PMID:32715994   PMID:32722781  
PMID:32728938   PMID:32730779   PMID:32732221   PMID:32753382   PMID:32796813   PMID:32811853   PMID:32812335   PMID:32814053   PMID:32814769   PMID:32833271   PMID:32843613   PMID:32859605  
PMID:32889391   PMID:32921221   PMID:32929371   PMID:32933752   PMID:32962742   PMID:32962858   PMID:32971884   PMID:32973789   PMID:32980885   PMID:32981916   PMID:32991338   PMID:33008815  
PMID:33009488   PMID:33014186   PMID:33020477   PMID:33024116   PMID:33031101   PMID:33037978   PMID:33046535   PMID:33051558   PMID:33078202   PMID:33079728   PMID:33086033   PMID:33092025  
PMID:33097685   PMID:33099868   PMID:33111613   PMID:33113263   PMID:33120427   PMID:33125136   PMID:33128283   PMID:33128474   PMID:33143224   PMID:33168821   PMID:33170359   PMID:33187130  
PMID:33199826   PMID:33208877   PMID:33228517   PMID:33234576   PMID:33293694   PMID:33298911   PMID:33301029   PMID:33303756   PMID:33318499   PMID:33336736   PMID:33340428   PMID:33340617  
PMID:33347625   PMID:33355622   PMID:33361851   PMID:33374332   PMID:33381997   PMID:33387362   PMID:33404608   PMID:33420360   PMID:33421273   PMID:33430425   PMID:33453168   PMID:33461590  
PMID:33462212   PMID:33472061   PMID:33472888   PMID:33476486   PMID:33480087   PMID:33483421   PMID:33494392   PMID:33527629   PMID:33528622   PMID:33533494   PMID:33537096   PMID:33541412  
PMID:33546726   PMID:33601056   PMID:33626175   PMID:33648560   PMID:33686491   PMID:33689920   PMID:33718387   PMID:33727660   PMID:33759958   PMID:33760210   PMID:33771538   PMID:33782411  
PMID:33785835   PMID:33798549   PMID:33799592   PMID:33821962   PMID:33849634   PMID:33856031   PMID:33894159   PMID:33896016   PMID:33914337   PMID:33931740   PMID:33954904   PMID:33961781  
PMID:33964277   PMID:33969640   PMID:33988072   PMID:34049792   PMID:34078046   PMID:34088288   PMID:34116677   PMID:34118203   PMID:34131801   PMID:34145038   PMID:34147029   PMID:34155628  
PMID:34168109   PMID:34168116   PMID:34192548   PMID:34196212   PMID:34233596   PMID:34257619   PMID:34274028   PMID:34283887   PMID:34310776   PMID:34319618   PMID:34321275   PMID:34325590  
PMID:34339013   PMID:34372899   PMID:34373451   PMID:34380369   PMID:34404765   PMID:34406978   PMID:34438040   PMID:34445161   PMID:34445233   PMID:34465901   PMID:34499581   PMID:34510316  
PMID:34512173   PMID:34528662   PMID:34534637   PMID:34584081   PMID:34591642   PMID:34601505   PMID:34610962   PMID:34612761   PMID:34650217   PMID:34671012   PMID:34671019   PMID:34688842  
PMID:34696771   PMID:34706096   PMID:34714590   PMID:34723715   PMID:34727403   PMID:34728235   PMID:34739417   PMID:34741373   PMID:34749168   PMID:34755101   PMID:34761308   PMID:34767926  
PMID:34788382   PMID:34803166   PMID:34843906   PMID:34849865   PMID:34850609   PMID:34862309   PMID:34864816   PMID:34890565   PMID:34911936   PMID:34930932   PMID:34967583   PMID:34980601  
PMID:35008557   PMID:35013218   PMID:35013227   PMID:35017527   PMID:35039060   PMID:35044719   PMID:35045798   PMID:35073601   PMID:35076962   PMID:35078507   PMID:35086951   PMID:35089787  
PMID:35130122   PMID:35140242   PMID:35149590   PMID:35152630   PMID:35167621   PMID:35182388   PMID:35195778   PMID:35210568   PMID:35216153   PMID:35216159   PMID:35217790   PMID:35231992  
PMID:35260179   PMID:35269569   PMID:35271311   PMID:35296779   PMID:35296795   PMID:35339800   PMID:35339914   PMID:35343073   PMID:35367823   PMID:35379056   PMID:35388487   PMID:35395974  
PMID:35397617   PMID:35411936   PMID:35414777   PMID:35428760   PMID:35438057   PMID:35475703   PMID:35511691   PMID:35522362   PMID:35546072   PMID:35562350   PMID:35593463   PMID:35596973  
PMID:35604033   PMID:35645127   PMID:35687110   PMID:35690961   PMID:35794848   PMID:35832114   PMID:35834140   PMID:35844805   PMID:35857872   PMID:35864508   PMID:35921902   PMID:35925524  
PMID:35933409   PMID:35940521   PMID:35963793   PMID:36002342   PMID:36003390   PMID:36033372   PMID:36051358   PMID:36059274   PMID:36077796   PMID:36153370   PMID:36155135   PMID:36156093  
PMID:36163081   PMID:36199071   PMID:36219392   PMID:36222892   PMID:36305094   PMID:36306337   PMID:36321415   PMID:36324030   PMID:36333840   PMID:36352191   PMID:36355424   PMID:36368728  
PMID:36369791   PMID:36395886   PMID:36403194   PMID:36403281   PMID:36424410   PMID:36433941   PMID:36433943   PMID:36442624   PMID:36473131   PMID:36474192   PMID:36525476   PMID:36528490  
PMID:36552889   PMID:36555426   PMID:36560881   PMID:36581205   PMID:36602428   PMID:36610315   PMID:36624401   PMID:36629054   PMID:36631007   PMID:36631876   PMID:36635500   PMID:36639831  
PMID:36672841   PMID:36692844   PMID:36708875   PMID:36721232   PMID:36746261   PMID:36765885   PMID:36803548   PMID:36893517   PMID:36893894   PMID:36906109   PMID:36907504   PMID:36963166  
PMID:36999462   PMID:37017854   PMID:37040401   PMID:37044092   PMID:37052757   PMID:37087547   PMID:37105715   PMID:37105989   PMID:37115490   PMID:37118982   PMID:37147437   PMID:37158894  
PMID:37167062   PMID:37201439   PMID:37202187   PMID:37212463   PMID:37219487   PMID:37224019   PMID:37225855   PMID:37236124   PMID:37236926   PMID:37280393   PMID:37301535   PMID:37317656  
PMID:37347737   PMID:37393598   PMID:37422352   PMID:37428010   PMID:37478862   PMID:37481674   PMID:37486991   PMID:37490552   PMID:37517480   PMID:37578465   PMID:37596667   PMID:37598282  
PMID:37656618   PMID:37685841   PMID:37704631   PMID:37713993   PMID:37739936   PMID:37788092   PMID:37797796   PMID:37815914   PMID:37827180   PMID:37828515   PMID:37833558   PMID:37848444  
PMID:37852796   PMID:37858127   PMID:37859625   PMID:37864183   PMID:37897298   PMID:37925449   PMID:37926284   PMID:37931534   PMID:37934799   PMID:37935302   PMID:37936306   PMID:37973687  
PMID:37980563   PMID:37983720   PMID:38003498   PMID:38031136   PMID:38031763   PMID:38037834   PMID:38039509   PMID:38050242   PMID:38082402   PMID:38093312   PMID:38101156   PMID:38115228  
PMID:38139353   PMID:38141607   PMID:38166947   PMID:38182548   PMID:38207206   PMID:38216914   PMID:38225354   PMID:38227944   PMID:38247322   PMID:38266312   PMID:38301392   PMID:38301858  
PMID:38315865   PMID:38318177   PMID:38335255   PMID:38408587   PMID:38426579   PMID:38454021   PMID:38457494   PMID:38532359   PMID:38547933   PMID:38553452   PMID:38578825   PMID:38620028  
PMID:38622518   PMID:38654006   PMID:38677725   PMID:38701261   PMID:38729555   PMID:38734194   PMID:38749608   PMID:38821916   PMID:38834613   PMID:38842567   PMID:38843019   PMID:38848040  
PMID:38862581   PMID:38877600   PMID:38881003   PMID:38911853   PMID:38967522   PMID:38971196   PMID:38981022   PMID:38982480   PMID:39003255   PMID:39018261   PMID:39085875   PMID:39110589  
PMID:39117654   PMID:39122009   PMID:39160158   PMID:39193992   PMID:39230995   PMID:39327253   PMID:39357549   PMID:39396848   PMID:39415271   PMID:39432777  


Genomics

Comparative Map Data
MYC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388127,735,434 - 127,742,951 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8127,735,434 - 127,742,951 (+)EnsemblGRCh38hg38GRCh38
GRCh378128,747,680 - 128,755,197 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368128,817,498 - 128,822,856 (+)NCBINCBI36Build 36hg18NCBI36
Build 348128,817,685 - 128,822,853NCBI
Celera8124,928,812 - 124,934,177 (+)NCBICelera
Cytogenetic Map8q24.21NCBI
HuRef8124,069,829 - 124,075,195 (+)NCBIHuRef
CHM1_18128,788,551 - 128,793,916 (+)NCBICHM1_1
T2T-CHM13v2.08128,862,888 - 128,870,405 (+)NCBIT2T-CHM13v2.0
Myc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391561,857,190 - 61,862,210 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1561,857,240 - 61,862,223 (+)EnsemblGRCm39 Ensembl
GRCm381561,985,341 - 61,990,361 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1561,985,391 - 61,990,374 (+)EnsemblGRCm38mm10GRCm38
MGSCv371561,816,896 - 61,821,916 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361561,815,052 - 61,820,027 (+)NCBIMGSCv36mm8
Celera1563,490,745 - 63,495,748 (+)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1526.19NCBI
Myc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8795,483,105 - 95,488,031 (+)NCBIGRCr8
mRatBN7.2793,593,705 - 93,598,633 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl793,593,705 - 93,598,630 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx795,416,828 - 95,421,746 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0797,619,124 - 97,624,042 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0797,498,652 - 97,503,571 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07102,586,313 - 102,591,240 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7102,586,313 - 102,591,240 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07103,157,452 - 103,162,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4798,953,142 - 98,958,060 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1798,987,371 - 98,992,287 (+)NCBI
Celera790,263,903 - 90,268,823 (+)NCBICelera
Cytogenetic Map7q33NCBI
Myc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554612,714,022 - 2,718,982 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554612,714,022 - 2,718,872 (+)NCBIChiLan1.0ChiLan1.0
MYC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27145,127,238 - 145,132,177 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18120,636,992 - 120,641,918 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08124,387,561 - 124,393,551 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18127,130,877 - 127,136,861 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8127,131,512 - 127,136,863 (+)Ensemblpanpan1.1panPan2
MYC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11325,200,772 - 25,205,309 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1325,200,577 - 25,205,309 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1325,169,176 - 25,173,718 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01325,544,697 - 25,549,239 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1325,539,647 - 25,549,749 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11325,260,451 - 25,264,991 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01325,374,618 - 25,379,158 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01325,629,077 - 25,633,621 (+)NCBIUU_Cfam_GSD_1.0
Myc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530313,054,869 - 13,059,826 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647020,480,829 - 20,485,965 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647020,480,844 - 20,485,955 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl412,455,122 - 12,461,078 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1412,455,141 - 12,460,360 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2412,778,452 - 12,783,667 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap4p13NCBI
MYC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18122,282,989 - 122,288,392 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8122,282,630 - 122,288,384 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603917,837,088 - 17,843,111 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473527,780,037 - 27,784,806 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473527,780,338 - 27,784,714 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MYC
31 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_002467.6(MYC):c.214C>T (p.Pro72Ser) single nucleotide variant Burkitt lymphoma [RCV000013402] Chr8:127738431 [GRCh38]
Chr8:128750677 [GRCh37]
Chr8:8q24.21
pathogenic
NM_002467.6(MYC):c.302A>C (p.Asn101Thr) single nucleotide variant Burkitt lymphoma [RCV000013403]|Neoplasm [RCV000431563] Chr8:127738519 [GRCh38]
Chr8:128750765 [GRCh37]
Chr8:8q24.21
pathogenic|likely pathogenic
NM_002467.6(MYC):c.162G>C (p.Glu54Asp) single nucleotide variant Burkitt lymphoma [RCV000013404] Chr8:127738379 [GRCh38]
Chr8:128750625 [GRCh37]
Chr8:8q24.21
pathogenic
NM_002467.6(MYC):c.220C>G (p.Pro74Ala) single nucleotide variant Burkitt lymphoma [RCV000013405]|Cholesteatoma of middle ear [RCV003159073] Chr8:127738437 [GRCh38]
Chr8:128750683 [GRCh37]
Chr8:8q24.21
pathogenic|other
GRCh38/hg38 8q24.21(chr8:127118340-127858575)x3 copy number gain See cases [RCV000050763] Chr8:127118340..127858575 [GRCh38]
Chr8:128130585..128870821 [GRCh37]
Chr8:128199767..128940003 [NCBI36]
Chr8:8q24.21
pathogenic
GRCh38/hg38 8q23.3-24.3(chr8:113580402-145054634)x3 copy number gain See cases [RCV000050638] Chr8:113580402..145054634 [GRCh38]
Chr8:114592631..146280020 [GRCh37]
Chr8:114661807..146250824 [NCBI36]
Chr8:8q23.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:95606052-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053677]|See cases [RCV000053677] Chr8:95606052..145054775 [GRCh38]
Chr8:96618280..146280161 [GRCh37]
Chr8:96687456..146250965 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124514090-145054634)x3 copy number gain See cases [RCV000053678] Chr8:124514090..145054634 [GRCh38]
Chr8:125526331..146280020 [GRCh37]
Chr8:125595512..146250824 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:244417-145054775)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053604]|See cases [RCV000053604] Chr8:244417..145054775 [GRCh38]
Chr8:194417..146280161 [GRCh37]
Chr8:184417..146250965 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q24.21-24.23(chr8:126626164-137169427)x1 copy number loss See cases [RCV000054306] Chr8:126626164..137169427 [GRCh38]
Chr8:127638409..138181670 [GRCh37]
Chr8:127707591..138250852 [NCBI36]
Chr8:8q24.21-24.23
pathogenic
NM_002467.6(MYC):c.223C>A (p.Pro75Thr) single nucleotide variant Cholesteatoma of middle ear [RCV003159078] Chr8:127738440 [GRCh38]
Chr8:128750686 [GRCh37]
Chr8:8q24.21
other
GRCh38/hg38 8q24.13-24.21(chr8:122454392-128513076)x3 copy number gain See cases [RCV000133620] Chr8:122454392..128513076 [GRCh38]
Chr8:123466631..129525322 [GRCh37]
Chr8:123535812..129594504 [NCBI36]
Chr8:8q24.13-24.21
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:94682154-145068656)x3 copy number gain See cases [RCV000134353] Chr8:94682154..145068656 [GRCh38]
Chr8:95694382..146294042 [GRCh37]
Chr8:95763558..146264846 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q21.3-24.23(chr8:86300584-137022587)x3 copy number gain See cases [RCV000135621] Chr8:86300584..137022587 [GRCh38]
Chr8:87312813..138034830 [GRCh37]
Chr8:87381929..138104012 [NCBI36]
Chr8:8q21.3-24.23
pathogenic|likely pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124498498-145068712)x3 copy number gain See cases [RCV000137346] Chr8:124498498..145068712 [GRCh38]
Chr8:125510739..146294098 [GRCh37]
Chr8:125579920..146264902 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
GRCh38/hg38 8q21.3-24.3(chr8:87931152-145068712)x3 copy number gain See cases [RCV000138551] Chr8:87931152..145068712 [GRCh38]
Chr8:88943380..146294098 [GRCh37]
Chr8:89012496..146264902 [NCBI36]
Chr8:8q21.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8q22.1-24.3(chr8:97382873-145070385)x3 copy number gain See cases [RCV000140447] Chr8:97382873..145070385 [GRCh38]
Chr8:98395101..146295771 [GRCh37]
Chr8:98464277..146266575 [NCBI36]
Chr8:8q22.1-24.3
pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:100867343-145070385)x3 copy number gain See cases [RCV000141694] Chr8:100867343..145070385 [GRCh38]
Chr8:101879571..146295771 [GRCh37]
Chr8:101948747..146266575 [NCBI36]
Chr8:8q22.3-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3
pathogenic
GRCh38/hg38 8q22.3-24.3(chr8:103306336-145068712)x3 copy number gain See cases [RCV000142810] Chr8:103306336..145068712 [GRCh38]
Chr8:104318564..146294098 [GRCh37]
Chr8:104387740..146264902 [NCBI36]
Chr8:8q22.3-24.3
pathogenic|likely pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3
pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000148092] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3
pathogenic
GRCh38/hg38 8q21.2-24.3(chr8:85765999-145070385)x3 copy number gain See cases [RCV000143659] Chr8:85765999..145070385 [GRCh38]
Chr8:86778228..146295771 [GRCh37]
Chr8:86863079..146266575 [NCBI36]
Chr8:8q21.2-24.3
pathogenic
GRCh38/hg38 8q24.13-24.3(chr8:124514090-145054634)x3 copy number gain See cases [RCV000148117] Chr8:124514090..145054634 [GRCh38]
Chr8:125526331..146280020 [GRCh37]
Chr8:125595512..146250824 [NCBI36]
Chr8:8q24.13-24.3
pathogenic
NM_002467.6(MYC):c.478G>A (p.Val160Ile) single nucleotide variant Premature ovarian failure [RCV001270210] Chr8:127738695 [GRCh38]
Chr8:128750941 [GRCh37]
Chr8:8q24.21
uncertain significance
GRCh37/hg19 8p23.3-q24.3(chr8:158991-146280828)x3 copy number gain See cases [RCV000447507] Chr8:158991..146280828 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
NM_002467.6(MYC):c.230C>T (p.Ser77Phe) single nucleotide variant Neoplasm [RCV000424357] Chr8:127738447 [GRCh38]
Chr8:128750693 [GRCh37]
Chr8:8q24.21
likely pathogenic
NM_002467.6(MYC):c.169C>T (p.Pro57Ser) single nucleotide variant Neoplasm [RCV000429575] Chr8:127738386 [GRCh38]
Chr8:128750632 [GRCh37]
Chr8:8q24.21
likely pathogenic
NM_002467.6(MYC):c.176C>T (p.Ala59Val) single nucleotide variant Neoplasm [RCV000440255] Chr8:127738393 [GRCh38]
Chr8:128750639 [GRCh37]
Chr8:8q24.21
likely pathogenic
NM_002467.6(MYC):c.173C>T (p.Pro58Leu) single nucleotide variant Carcinoma of esophagus [RCV000428982]|Lung adenocarcinoma [RCV000427867]|Malignant melanoma of skin [RCV000438593]|Neuroblastoma [RCV000436178]|Non-Hodgkin lymphoma [RCV000418915] Chr8:127738390 [GRCh38]
Chr8:128750636 [GRCh37]
Chr8:8q24.21
likely pathogenic
NM_002467.6(MYC):c.218C>T (p.Thr73Ile) single nucleotide variant Carcinoma of esophagus [RCV000434207]|Lung adenocarcinoma [RCV000430246]|Malignant melanoma of skin [RCV000440950]|Neoplasm [RCV000423713]|Neuroblastoma [RCV000441422]|Non-Hodgkin lymphoma [RCV000419562] Chr8:127738435 [GRCh38]
Chr8:128750681 [GRCh37]
Chr8:8q24.21
likely pathogenic
NM_002467.6(MYC):c.217A>C (p.Thr73Pro) single nucleotide variant Carcinoma of esophagus [RCV000438328]|Lung adenocarcinoma [RCV000445053]|Malignant melanoma of skin [RCV000437207]|Neuroblastoma [RCV000420006]|Non-Hodgkin lymphoma [RCV000426528] Chr8:127738434 [GRCh38]
Chr8:128750680 [GRCh37]
Chr8:8q24.21
likely pathogenic
NM_002467.6(MYC):c.778C>G (p.Pro260Ala) single nucleotide variant Neoplasm [RCV000444724] Chr8:127738995 [GRCh38]
Chr8:128751241 [GRCh37]
Chr8:8q24.21
likely pathogenic
GRCh37/hg19 8q22.1-24.3(chr8:98432250-146222672)x4 copy number gain See cases [RCV000448954] Chr8:98432250..146222672 [GRCh37]
Chr8:8q22.1-24.3
pathogenic
GRCh37/hg19 8q24.21-24.22(chr8:128295596-133200773)x1 copy number loss See cases [RCV000448960] Chr8:128295596..133200773 [GRCh37]
Chr8:8q24.21-24.22
likely pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771) copy number gain See cases [RCV000510234] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.3-24.3(chr8:93047482-141355635)x3 copy number gain See cases [RCV000511761] Chr8:93047482..141355635 [GRCh37]
Chr8:8q21.3-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158049-146295771)x3 copy number gain See cases [RCV000511095] Chr8:158049..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841154-146295771)x3 copy number gain See cases [RCV000511002] Chr8:86841154..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:86841228-142689874)x3 copy number gain See cases [RCV000510854] Chr8:86841228..142689874 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q23.3-24.3(chr8:114853126-146295771)x3 copy number gain See cases [RCV000512401] Chr8:114853126..146295771 [GRCh37]
Chr8:8q23.3-24.3
pathogenic
GRCh37/hg19 8p23.1-q24.3(chr8:12490999-146295771)x3 copy number gain See cases [RCV000512169] Chr8:12490999..146295771 [GRCh37]
Chr8:8p23.1-q24.3
pathogenic
GRCh37/hg19 8q24.12-24.3(chr8:121694649-146295771)x3 copy number gain not provided [RCV000683044] Chr8:121694649..146295771 [GRCh37]
Chr8:8q24.12-24.3
pathogenic
Single allele deletion Trichorhinophalangeal dysplasia type I [RCV000735900] Chr8:114508086..129040004 [GRCh37]
Chr8:8q23.3-24.21
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:164984-146293414)x3 copy number gain not provided [RCV000747254] Chr8:164984..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:10213-146293414)x3 copy number gain not provided [RCV000747248] Chr8:10213..146293414 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q24.21(chr8:128750260-128758861)x3 copy number gain not provided [RCV000747835] Chr8:128750260..128758861 [GRCh37]
Chr8:8q24.21
benign
GRCh37/hg19 8q24.21(chr8:128750494-128753204)x3 copy number gain not provided [RCV000999115] Chr8:128750494..128753204 [GRCh37]
Chr8:8q24.21
likely pathogenic
NM_002467.6(MYC):c.144G>A (p.Gln48=) single nucleotide variant not provided [RCV000974095] Chr8:127738361 [GRCh38]
Chr8:128750607 [GRCh37]
Chr8:8q24.21
benign
GRCh37/hg19 8q24.13-24.3(chr8:126892814-143750028)x1 copy number loss not provided [RCV001006144] Chr8:126892814..143750028 [GRCh37]
Chr8:8q24.13-24.3
pathogenic
GRCh37/hg19 8q24.13-24.22(chr8:124120772-135265846)x1 copy number loss not provided [RCV000848438] Chr8:124120772..135265846 [GRCh37]
Chr8:8q24.13-24.22
pathogenic
GRCh37/hg19 8q24.12-24.3(chr8:122193546-146295771)x3 copy number gain not provided [RCV000849762] Chr8:122193546..146295771 [GRCh37]
Chr8:8q24.12-24.3
pathogenic
GRCh37/hg19 8q24.13-24.3(chr8:125496223-146295771)x3 copy number gain not provided [RCV000845705] Chr8:125496223..146295771 [GRCh37]
Chr8:8q24.13-24.3
pathogenic
GRCh37/hg19 8q24.13-24.21(chr8:123074293-131113892)x1 copy number loss not provided [RCV000848164] Chr8:123074293..131113892 [GRCh37]
Chr8:8q24.13-24.21
pathogenic
GRCh37/hg19 8p12-q24.3(chr8:31936551-146295771)x3 copy number gain not provided [RCV000848192] Chr8:31936551..146295771 [GRCh37]
Chr8:8p12-q24.3
pathogenic
NM_002467.6(MYC):c.1085C>T (p.Ser362Phe) single nucleotide variant not provided [RCV000892872] Chr8:127740678 [GRCh38]
Chr8:128752924 [GRCh37]
Chr8:8q24.21
benign|likely benign
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not provided [RCV000848478] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
NM_002467.6(MYC):c.64T>C (p.Phe22Leu) single nucleotide variant not provided [RCV000896531] Chr8:127738281 [GRCh38]
Chr8:128750527 [GRCh37]
Chr8:8q24.21
benign|likely benign
NM_002467.6(MYC):c.409G>C (p.Glu137Gln) single nucleotide variant not specified [RCV004138944] Chr8:127738626 [GRCh38]
Chr8:128750872 [GRCh37]
Chr8:8q24.21
uncertain significance
GRCh37/hg19 8q24.12-24.3(chr8:121042467-146295771)x3 copy number gain not provided [RCV001006140] Chr8:121042467..146295771 [GRCh37]
Chr8:8q24.12-24.3
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771) copy number gain Polydactyly [RCV002280629] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q21.2-24.3(chr8:84712253-146295771)x3 copy number gain See cases [RCV002285066] Chr8:84712253..146295771 [GRCh37]
Chr8:8q21.2-24.3
pathogenic
GRCh37/hg19 8q24.21(chr8:128717255-128918996)x3 copy number gain not provided [RCV001834390] Chr8:128717255..128918996 [GRCh37]
Chr8:8q24.21
likely benign
NM_002467.6(MYC):c.77A>G (p.Asn26Ser) single nucleotide variant Classic Hodgkin lymphoma [RCV002227948]|MYC-related disorder [RCV003971198]|not provided [RCV004694177] Chr8:127738294 [GRCh38]
Chr8:127738294..127738295 [GRCh38]
Chr8:128750540 [GRCh37]
Chr8:128750540..128750541 [GRCh37]
Chr8:8q24.21
benign|uncertain significance
GRCh37/hg19 8q13.2-24.3(chr8:70382990-146295771) copy number gain not specified [RCV002053772] Chr8:70382990..146295771 [GRCh37]
Chr8:8q13.2-24.3
pathogenic
GRCh37/hg19 8q22.1-24.3(chr8:96496503-146295711) copy number gain not provided [RCV002221452] Chr8:96496503..146295711 [GRCh37]
Chr8:8q22.1-24.3
pathogenic
GRCh37/hg19 8q13.2-24.3(chr8:68912432-146295771)x2 copy number gain See cases [RCV002292707] Chr8:68912432..146295771 [GRCh37]
Chr8:8q13.2-24.3
pathogenic
NM_002467.6(MYC):c.671C>T (p.Ala224Val) single nucleotide variant not specified [RCV004282123] Chr8:127738888 [GRCh38]
Chr8:128751134 [GRCh37]
Chr8:8q24.21
uncertain significance
GRCh37/hg19 8q23.3-24.22(chr8:112234557-133668379)x1 copy number loss not provided [RCV002474553] Chr8:112234557..133668379 [GRCh37]
Chr8:8q23.3-24.22
pathogenic
GRCh38/hg38 8q23.3-24.23(chr8:115586904-135607135)x3 copy number gain Neurodevelopmental disorder [RCV003327615] Chr8:115586904..135607135 [GRCh38]
Chr8:8q23.3-24.23
pathogenic
NM_002467.6(MYC):c.909C>G (p.Ser303Arg) single nucleotide variant not specified [RCV004258900] Chr8:127740502 [GRCh38]
Chr8:128752748 [GRCh37]
Chr8:8q24.21
uncertain significance
NM_002467.6(MYC):c.31-172G>A single nucleotide variant not provided [RCV003440641] Chr8:127738076 [GRCh38]
Chr8:128750322 [GRCh37]
Chr8:8q24.21
benign
NM_002467.6(MYC):c.30+600C>T single nucleotide variant not provided [RCV003440640] Chr8:127737223 [GRCh38]
Chr8:128749469 [GRCh37]
Chr8:8q24.21
benign
NM_002467.6(MYC):c.30+4A>T single nucleotide variant not provided [RCV003440639] Chr8:127736627 [GRCh38]
Chr8:128748873 [GRCh37]
Chr8:8q24.21
uncertain significance
NM_002467.6(MYC):c.217A>G (p.Thr73Ala) single nucleotide variant not provided [RCV003440642] Chr8:127738434 [GRCh38]
Chr8:128750680 [GRCh37]
Chr8:8q24.21
pathogenic
NM_002467.6(MYC):c.-96C>T single nucleotide variant not provided [RCV003440638] Chr8:127736498 [GRCh38]
Chr8:128748744 [GRCh37]
Chr8:8q24.21
benign
NM_002467.6(MYC):c.-263G>A single nucleotide variant not provided [RCV003440637] Chr8:127736331 [GRCh38]
Chr8:128748577 [GRCh37]
Chr8:8q24.21
likely benign
GRCh37/hg19 8q24.13-24.21(chr8:124534271-129054138)x4 copy number gain Distal trisomy 8q [RCV003458956] Chr8:124534271..129054138 [GRCh37]
Chr8:8q24.13-24.21
pathogenic
GRCh37/hg19 8p23.3-q24.3(chr8:158048-146295771)x3 copy number gain not specified [RCV003986742] Chr8:158048..146295771 [GRCh37]
Chr8:8p23.3-q24.3
pathogenic
GRCh37/hg19 8q24.11-24.22(chr8:118071721-132774256)x1 copy number loss not specified [RCV003986782] Chr8:118071721..132774256 [GRCh37]
Chr8:8q24.11-24.22
pathogenic
GRCh37/hg19 8q23.3-24.3(chr8:113392581-146364022)x3 copy number gain not provided [RCV003885521] Chr8:113392581..146364022 [GRCh37]
Chr8:8q23.3-24.3
pathogenic
NM_002467.6(MYC):c.438G>A (p.Gln146=) single nucleotide variant MYC-related disorder [RCV003977180] Chr8:127738655 [GRCh38]
Chr8:128750901 [GRCh37]
Chr8:8q24.21
likely benign
NM_002467.6(MYC):c.738G>A (p.Pro246=) single nucleotide variant MYC-related disorder [RCV003974054] Chr8:127738955 [GRCh38]
Chr8:128751201 [GRCh37]
Chr8:8q24.21
benign
NM_002467.6(MYC):c.1297G>C (p.Asp433His) single nucleotide variant not specified [RCV004451812] Chr8:127740890 [GRCh38]
Chr8:128753136 [GRCh37]
Chr8:8q24.21
uncertain significance
NM_002467.6(MYC):c.544G>A (p.Gly182Ser) single nucleotide variant not specified [RCV004649609] Chr8:127738761 [GRCh38]
Chr8:128751007 [GRCh37]
Chr8:8q24.21
uncertain significance
NM_002467.6(MYC):c.1228A>G (p.Ile410Val) single nucleotide variant not specified [RCV004451809] Chr8:127740821 [GRCh38]
Chr8:128753067 [GRCh37]
Chr8:8q24.21
uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR212hsa-miR-212-3pOncomiRDBexternal_infoNANA21053104
MIR98hsa-miR-98-5pMirtarbaseexternal_infoLuciferase reporter assay//Northern blot//qRT-PCR/Functional MTI19528081
MIR98hsa-miR-98-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)17942906
MIR429hsa-miR-429Tarbaseexternal_infoOtherPOSITIVE
MIR34Chsa-miR-34c-5pMirecordsexternal_info{changed}NA20212154
MIR429hsa-miR-429Mirtarbaseexternal_infoReporter assay;Western blot;OtherFunctional MTI21684154
MIR429hsa-miR-429Tarbaseexternal_infoWesternblitPOSITIVE
MIR20Ahsa-miR-20a-5pMirtarbaseexternal_infoWestern blotFunctional MTI18695042
MIR429hsa-miR-429OncomiRDBexternal_infoNANA21684154
MIR26A1hsa-miR-26a-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI19524505
MIRLET7Ehsa-let-7e-5pOncomiRDBexternal_infoNANA20525879
MIRLET7A2hsa-let-7a-5pOncomiRDBexternal_infoNANA20525879
MIRLET7Bhsa-let-7b-5pOncomiRDBexternal_infoNANA20525879
MIR451Ahsa-miR-451aMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21464222
MIRLET7Dhsa-let-7d-5pOncomiRDBexternal_infoNANA20525879
MIRLET7Chsa-let-7c-5pMirtarbaseexternal_infoLuciferase reporter assay//Northern blot//Western Functional MTI17877811
MIR378Ahsa-miR-378a-3pMirtarbaseexternal_infoImmunoblot//Luciferase reporter assay//qRT-PCRFunctional MTI21242960
MIRLET7Chsa-let-7c-5pOncomiRDBexternal_infoNANA20525879
MIRLET7Chsa-let-7c-3pMirecordsexternal_info{changed}NA17877811
MIR335hsa-miR-335-5pMirtarbaseexternal_infoWestern blotFunctional MTI21618216
MIR34Ahsa-miR-34a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blot//Reporter Functional MTI19696787
MIR34Ahsa-miR-34a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21294122
MIR34Ahsa-miR-34a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22159222
MIR34Ahsa-miR-34a-5pMirtarbaseexternal_infoSequencingFunctional MTI (Weak)20371350
MIR145hsa-miR-145-5pOncomiRDBexternal_infoNANA21075312
MIR145hsa-miR-145-5pOncomiRDBexternal_infoNANA19202062
MIR145hsa-miR-145-3pMirecordsexternal_info{changed}NA19202062
MIRLET7F2hsa-let-7f-5pOncomiRDBexternal_infoNANA20525879
MIRLET7F1hsa-let-7f-5pOncomiRDBexternal_infoNANA20525879
MIR26A2hsa-miR-26a-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI19524505
MIR145hsa-miR-145-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI19202062
MIR145hsa-miR-145-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21092188
MIR145hsa-miR-145-5pOncomiRDBexternal_infoNANA21092188
MIR34Ahsa-miR-34a-5pTarbaseexternal_infoMicroarrayNEGATIVE
MIR34Ahsa-miR-34a-5pOncomiRDBexternal_infoNANA22235332
MIR34Ahsa-miR-34a-5pOncomiRDBexternal_infoNANA22159222
MIR34Ahsa-miR-34a-5pOncomiRDBexternal_infoNANA21297663
MIR34Ahsa-miR-34a-3pMirecordsexternal_info{changed}NA20212154
MIRLET7Ihsa-let-7i-5pOncomiRDBexternal_infoNANA20525879
MIR449Chsa-miR-449c-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23507140
MIR34Bhsa-miR-34b-3pMirtarbaseexternal_infoImmunohistochemistry//qRT-PCRFunctional MTI (Weak)18802929
MIR34Bhsa-miR-34b-3pMirecordsexternal_info{changed}NA18802929
MIR135A2hsa-miR-135a-5pOncomiRDBexternal_infoNANA23176581
MIR34Ahsa-miR-34a-5pOncomiRDBexternal_infoNANA19696787
MIRLET7A2hsa-let-7a-5pMirtarbaseexternal_infoWestern blotFunctional MTI20033209
MIRLET7A2hsa-let-7a-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)17942906
MIRLET7A2hsa-let-7a-5pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI16651716
MIRLET7Ghsa-let-7g-5pTarbaseexternal_infoqPCRNEGATIVE
MIRLET7Ghsa-let-7g-5pOncomiRDBexternal_infoNANA20525879
MIRLET7Ghsa-let-7g-5pOncomiRDBexternal_infoNANA20309945
MIR17hsa-miR-17-5pMirtarbaseexternal_infoWestern blotFunctional MTI18695042
MIR135A1hsa-miR-135a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI23176581
MIR135A1hsa-miR-135a-5pOncomiRDBexternal_infoNANA23176581
MIRLET7A1hsa-let-7a-5pMirtarbaseexternal_infoWestern blotFunctional MTI20033209
MIRLET7A1hsa-let-7a-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)17942906
MIRLET7A1hsa-let-7a-5pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI16651716
MIRLET7A1hsa-let-7a-5pOncomiRDBexternal_infoNANA20525879
MIRLET7A1hsa-let-7a-3pTarbaseexternal_infoWesternblitPOSITIVE
MIRLET7Ghsa-let-7g-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blot//Functional MTI20309945
MIRLET7Ghsa-let-7g-5pMirtarbaseexternal_infoqRT-PCRNon-Functional MTI (Weak)21618519
MIR135A2hsa-miR-135a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI23176581

Predicted Target Of
Summary Value
Count of predictions:958
Count of miRNA genes:645
Interacting mature miRNAs:724
Transcripts:ENST00000259523, ENST00000377970, ENST00000517291, ENST00000520751, ENST00000524013
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407266342GWAS915318_Hbody height QTL GWAS915318 (human)2e-11body height (VT:0001253)body height (CMO:0000106)8127736252127736253Human
407266349GWAS915325_Hbody height QTL GWAS915325 (human)8e-15body height (VT:0001253)body height (CMO:0000106)8127738294127738295Human

Markers in Region
WI-19203  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,753,274 - 128,753,536UniSTSGRCh37
Build 368128,822,456 - 128,822,718RGDNCBI36
Celera8124,933,771 - 124,934,033RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,074,789 - 124,075,051UniSTS
GeneMap99-GB4 RH Map8490.78UniSTS
Whitehead-RH Map8655.6UniSTS
GDB:178394  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,752,072 - 128,752,547UniSTSGRCh37
Build 368128,821,254 - 128,821,729RGDNCBI36
Celera8124,932,569 - 124,933,044RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,073,587 - 124,074,062UniSTS
UniSTS:256954  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,750,637 - 128,750,913UniSTSGRCh37
Build 368128,819,819 - 128,820,095RGDNCBI36
Celera8124,931,134 - 124,931,410RGD
HuRef8124,072,151 - 124,072,427UniSTS
PMC102803P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,753,205 - 128,753,643UniSTSGRCh37
Build 368128,822,387 - 128,822,825RGDNCBI36
Celera8124,933,702 - 124,934,140RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,074,720 - 124,075,158UniSTS
PMC108928P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,746,751 - 128,747,122UniSTSGRCh37
Build 368128,815,933 - 128,816,304RGDNCBI36
Celera8124,927,248 - 124,927,619RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,068,264 - 124,068,636UniSTS
PMC127396P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,749,023 - 128,749,276UniSTSGRCh37
Build 368128,818,205 - 128,818,458RGDNCBI36
Celera8124,929,520 - 124,929,773RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,070,537 - 124,070,790UniSTS
PMC127396P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,748,659 - 128,749,060UniSTSGRCh37
Build 368128,817,841 - 128,818,242RGDNCBI36
Celera8124,929,156 - 124,929,557RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,070,173 - 124,070,574UniSTS
PMC127396P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,748,253 - 128,748,733UniSTSGRCh37
Build 368128,817,435 - 128,817,915RGDNCBI36
Celera8124,928,750 - 124,929,230RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,069,767 - 124,070,247UniSTS
PMC129440P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,748,075 - 128,748,935UniSTSGRCh37
Build 368128,817,257 - 128,818,117RGDNCBI36
Celera8124,928,572 - 124,929,432RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,069,589 - 124,070,449UniSTS
PMC134733P6  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,747,429 - 128,747,728UniSTSGRCh37
Build 368128,816,611 - 128,816,910RGDNCBI36
Celera8124,927,926 - 124,928,225RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,068,943 - 124,069,242UniSTS
PMC140827P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,750,525 - 128,750,921UniSTSGRCh37
Build 368128,819,707 - 128,820,103RGDNCBI36
Celera8124,931,022 - 124,931,418RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,072,039 - 124,072,435UniSTS
PMC150726P6  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,752,699 - 128,753,150UniSTSGRCh37
Build 368128,821,881 - 128,822,332RGDNCBI36
Celera8124,933,196 - 124,933,647RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,074,214 - 124,074,665UniSTS
PMC150726P9  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,750,642 - 128,751,041UniSTSGRCh37
Build 368128,819,824 - 128,820,223RGDNCBI36
Celera8124,931,139 - 124,931,538RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,072,156 - 124,072,555UniSTS
PMC156147P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,750,533 - 128,750,675UniSTSGRCh37
Build 368128,819,715 - 128,819,857RGDNCBI36
Celera8124,931,030 - 124,931,172RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,072,047 - 124,072,189UniSTS
PMC193934P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,746,659 - 128,746,969UniSTSGRCh37
Build 368128,815,841 - 128,816,151RGDNCBI36
Celera8124,927,156 - 124,927,466RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,068,172 - 124,068,482UniSTS
PMC209426P2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,752,774 - 128,752,854UniSTSGRCh37
Build 368128,821,956 - 128,822,036RGDNCBI36
Celera8124,933,271 - 124,933,351RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,074,289 - 124,074,369UniSTS
PMC303366P10  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,752,720 - 128,752,945UniSTSGRCh37
Build 368128,821,902 - 128,822,127RGDNCBI36
Celera8124,933,217 - 124,933,442RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,074,235 - 124,074,460UniSTS
PMC309637P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,746,700 - 128,747,027UniSTSGRCh37
Build 368128,815,882 - 128,816,209RGDNCBI36
Celera8124,927,197 - 124,927,524RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,068,213 - 124,068,541UniSTS
RH78926  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,751,095 - 128,751,238UniSTSGRCh37
Build 368128,820,277 - 128,820,420RGDNCBI36
Celera8124,931,592 - 124,931,735RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,072,609 - 124,072,752UniSTS
GeneMap99-GB4 RH Map8493.51UniSTS
D8S1980  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,753,205 - 128,753,538UniSTSGRCh37
Build 368128,822,387 - 128,822,720RGDNCBI36
Celera8124,933,702 - 124,934,035RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,074,720 - 124,075,053UniSTS
TNG Radiation Hybrid Map862704.0UniSTS
Stanford-G3 RH Map83919.0UniSTS
Whitehead-YAC Contig Map8 UniSTS
GeneMap99-G3 RH Map84009.0UniSTS
G15987  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,750,542 - 128,750,662UniSTSGRCh37
Build 368128,819,724 - 128,819,844RGDNCBI36
Celera8124,931,039 - 124,931,159RGD
Cytogenetic Map8q24.21UniSTS
HuRef8124,072,056 - 124,072,176UniSTS
MARC_31575-31576:1045674460:1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,752,673 - 128,753,189UniSTSGRCh37
Build 368128,821,855 - 128,822,371RGDNCBI36
Celera8124,933,170 - 124,933,686RGD
HuRef8124,074,188 - 124,074,704UniSTS
MYC_3297  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,752,650 - 128,753,485UniSTSGRCh37
Build 368128,821,832 - 128,822,667RGDNCBI36
Celera8124,933,147 - 124,933,982RGD
HuRef8124,074,165 - 124,075,000UniSTS
MYC  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,751,097 - 128,752,765UniSTSGRCh37
GRCh378128,750,838 - 128,751,041UniSTSGRCh37
Celera8124,931,594 - 124,933,262UniSTS
Celera8124,931,335 - 124,931,538UniSTS
HuRef8124,072,352 - 124,072,555UniSTS
HuRef8124,072,611 - 124,074,280UniSTS
MYC  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh378128,751,097 - 128,752,765UniSTSGRCh37
GRCh378128,750,838 - 128,751,041UniSTSGRCh37
Celera8124,931,594 - 124,933,262UniSTS
Celera8124,931,335 - 124,931,538UniSTS
HuRef8124,072,352 - 124,072,555UniSTS
HuRef8124,072,611 - 124,074,280UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
1204 2434 2788 2246 4946 1723 2346 4 623 1951 464 2268 7286 6458 53 3711 1 849 1735 1612 173

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_007161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001354870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA807892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB303308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC103819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF002859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002904 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ586971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ586972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ601396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ601397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ601398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ601399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ601405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM287187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX057136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY214166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG499628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BK006467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT019768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS542411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS566150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D10493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EH335289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC084226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI519542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI574342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JB171960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JB741130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  K02276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC782559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT583952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX302150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC164671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M12026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M12027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M19724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M20605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OK335781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OK335782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S65124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V00568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X00676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X53248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X54629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000259523   ⟹   ENSP00000259523
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,735,434 - 127,740,477 (+)Ensembl
Ensembl Acc Id: ENST00000377970   ⟹   ENSP00000367207
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,736,084 - 127,741,434 (+)Ensembl
Ensembl Acc Id: ENST00000517291   ⟹   ENSP00000429441
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,735,519 - 127,738,772 (+)Ensembl
Ensembl Acc Id: ENST00000520751
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,736,231 - 127,738,475 (+)Ensembl
Ensembl Acc Id: ENST00000524013   ⟹   ENSP00000430235
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,736,220 - 127,741,372 (+)Ensembl
Ensembl Acc Id: ENST00000621592   ⟹   ENSP00000478887
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,736,231 - 127,742,951 (+)Ensembl
Ensembl Acc Id: ENST00000641036   ⟹   ENSP00000493145
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,736,046 - 127,736,612 (+)Ensembl
Ensembl Acc Id: ENST00000641252   ⟹   ENSP00000493139
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,735,473 - 127,735,817 (+)Ensembl
Ensembl Acc Id: ENST00000651626   ⟹   ENSP00000499182
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,735,659 - 127,741,434 (+)Ensembl
Ensembl Acc Id: ENST00000652288   ⟹   ENSP00000499105
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,737,621 - 127,741,434 (+)Ensembl
Ensembl Acc Id: ENST00000707113   ⟹   ENSP00000516742
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,736,958 - 127,741,434 (+)Ensembl
Ensembl Acc Id: ENST00000707114   ⟹   ENSP00000516743
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,737,724 - 127,741,434 (+)Ensembl
Ensembl Acc Id: ENST00000707115   ⟹   ENSP00000516744
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,737,737 - 127,741,434 (+)Ensembl
Ensembl Acc Id: ENST00000707116   ⟹   ENSP00000516745
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,737,745 - 127,741,434 (+)Ensembl
Ensembl Acc Id: ENST00000707117
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl8127,739,073 - 127,741,434 (+)Ensembl
RefSeq Acc Id: NM_001354870   ⟹   NP_001341799
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388127,735,434 - 127,742,951 (+)NCBI
T2T-CHM13v2.08128,862,888 - 128,870,405 (+)NCBI
Sequence:
RefSeq Acc Id: NM_002467   ⟹   NP_002458
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh388127,736,231 - 127,742,951 (+)NCBI
GRCh378128,748,315 - 128,753,680 (+)ENTREZGENE
Build 368128,817,498 - 128,822,856 (+)NCBI Archive
HuRef8124,069,829 - 124,075,195 (+)ENTREZGENE
CHM1_18128,788,551 - 128,793,916 (+)NCBI
T2T-CHM13v2.08128,863,685 - 128,870,405 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001341799 (Get FASTA)   NCBI Sequence Viewer  
  NP_002458 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA36340 (Get FASTA)   NCBI Sequence Viewer  
  AAA59880 (Get FASTA)   NCBI Sequence Viewer  
  AAA59881 (Get FASTA)   NCBI Sequence Viewer  
  AAA59882 (Get FASTA)   NCBI Sequence Viewer  
  AAA59884 (Get FASTA)   NCBI Sequence Viewer  
  AAA59886 (Get FASTA)   NCBI Sequence Viewer  
  AAA88090 (Get FASTA)   NCBI Sequence Viewer  
  AAA88091 (Get FASTA)   NCBI Sequence Viewer  
  AAA88092 (Get FASTA)   NCBI Sequence Viewer  
  AAA88093 (Get FASTA)   NCBI Sequence Viewer  
  AAA88094 (Get FASTA)   NCBI Sequence Viewer  
  AAA88095 (Get FASTA)   NCBI Sequence Viewer  
  AAH00141 (Get FASTA)   NCBI Sequence Viewer  
  AAH00917 (Get FASTA)   NCBI Sequence Viewer  
  AAH58901 (Get FASTA)   NCBI Sequence Viewer  
  AAO31951 (Get FASTA)   NCBI Sequence Viewer  
  AAV38573 (Get FASTA)   NCBI Sequence Viewer  
  ABW69847 (Get FASTA)   NCBI Sequence Viewer  
  AGV06354 (Get FASTA)   NCBI Sequence Viewer  
  BAG35731 (Get FASTA)   NCBI Sequence Viewer  
  BAG64849 (Get FASTA)   NCBI Sequence Viewer  
  BBA22644 (Get FASTA)   NCBI Sequence Viewer  
  CAA23831 (Get FASTA)   NCBI Sequence Viewer  
  CAA25095 (Get FASTA)   NCBI Sequence Viewer  
  CAA25288 (Get FASTA)   NCBI Sequence Viewer  
  CAA46984 (Get FASTA)   NCBI Sequence Viewer  
  CAC22425 (Get FASTA)   NCBI Sequence Viewer  
  CAL18306 (Get FASTA)   NCBI Sequence Viewer  
  CAL18307 (Get FASTA)   NCBI Sequence Viewer  
  CAL18308 (Get FASTA)   NCBI Sequence Viewer  
  CAL18309 (Get FASTA)   NCBI Sequence Viewer  
  CAL18310 (Get FASTA)   NCBI Sequence Viewer  
  CAL18311 (Get FASTA)   NCBI Sequence Viewer  
  CAL18312 (Get FASTA)   NCBI Sequence Viewer  
  CAL18313 (Get FASTA)   NCBI Sequence Viewer  
  CAL18314 (Get FASTA)   NCBI Sequence Viewer  
  CAL18315 (Get FASTA)   NCBI Sequence Viewer  
  CAL18316 (Get FASTA)   NCBI Sequence Viewer  
  CAL18317 (Get FASTA)   NCBI Sequence Viewer  
  CAL18318 (Get FASTA)   NCBI Sequence Viewer  
  CAL18319 (Get FASTA)   NCBI Sequence Viewer  
  CAL18320 (Get FASTA)   NCBI Sequence Viewer  
  CAL18321 (Get FASTA)   NCBI Sequence Viewer  
  CAL18322 (Get FASTA)   NCBI Sequence Viewer  
  CAL18323 (Get FASTA)   NCBI Sequence Viewer  
  CAL18324 (Get FASTA)   NCBI Sequence Viewer  
  CAL18325 (Get FASTA)   NCBI Sequence Viewer  
  CAL18326 (Get FASTA)   NCBI Sequence Viewer  
  CAL18327 (Get FASTA)   NCBI Sequence Viewer  
  CAL18328 (Get FASTA)   NCBI Sequence Viewer  
  CAL18329 (Get FASTA)   NCBI Sequence Viewer  
  CAL18330 (Get FASTA)   NCBI Sequence Viewer  
  CAL18331 (Get FASTA)   NCBI Sequence Viewer  
  CAL18332 (Get FASTA)   NCBI Sequence Viewer  
  CAL18333 (Get FASTA)   NCBI Sequence Viewer  
  CAL18334 (Get FASTA)   NCBI Sequence Viewer  
  CAL18335 (Get FASTA)   NCBI Sequence Viewer  
  CAL18336 (Get FASTA)   NCBI Sequence Viewer  
  CAL18337 (Get FASTA)   NCBI Sequence Viewer  
  CAL18338 (Get FASTA)   NCBI Sequence Viewer  
  CAL18340 (Get FASTA)   NCBI Sequence Viewer  
  CAL18341 (Get FASTA)   NCBI Sequence Viewer  
  CAL18342 (Get FASTA)   NCBI Sequence Viewer  
  CAL18343 (Get FASTA)   NCBI Sequence Viewer  
  CAL18344 (Get FASTA)   NCBI Sequence Viewer  
  CAL18345 (Get FASTA)   NCBI Sequence Viewer  
  CAL18346 (Get FASTA)   NCBI Sequence Viewer  
  CAL18347 (Get FASTA)   NCBI Sequence Viewer  
  CAL18348 (Get FASTA)   NCBI Sequence Viewer  
  CAL18349 (Get FASTA)   NCBI Sequence Viewer  
  CAL18350 (Get FASTA)   NCBI Sequence Viewer  
  CAL18351 (Get FASTA)   NCBI Sequence Viewer  
  CAL18352 (Get FASTA)   NCBI Sequence Viewer  
  CAL18353 (Get FASTA)   NCBI Sequence Viewer  
  CAL18354 (Get FASTA)   NCBI Sequence Viewer  
  CAL18355 (Get FASTA)   NCBI Sequence Viewer  
  CAL18356 (Get FASTA)   NCBI Sequence Viewer  
  CAL18357 (Get FASTA)   NCBI Sequence Viewer  
  CAL18358 (Get FASTA)   NCBI Sequence Viewer  
  CAL18359 (Get FASTA)   NCBI Sequence Viewer  
  CAL18360 (Get FASTA)   NCBI Sequence Viewer  
  CAL18361 (Get FASTA)   NCBI Sequence Viewer  
  CAL18362 (Get FASTA)   NCBI Sequence Viewer  
  CAL18363 (Get FASTA)   NCBI Sequence Viewer  
  CAL18364 (Get FASTA)   NCBI Sequence Viewer  
  CAL18365 (Get FASTA)   NCBI Sequence Viewer  
  CAL18366 (Get FASTA)   NCBI Sequence Viewer  
  CAL18367 (Get FASTA)   NCBI Sequence Viewer  
  CAL18368 (Get FASTA)   NCBI Sequence Viewer  
  CAL18369 (Get FASTA)   NCBI Sequence Viewer  
  CAL18370 (Get FASTA)   NCBI Sequence Viewer  
  CAL18371 (Get FASTA)   NCBI Sequence Viewer  
  CAL18372 (Get FASTA)   NCBI Sequence Viewer  
  CAL18373 (Get FASTA)   NCBI Sequence Viewer  
  CAL18374 (Get FASTA)   NCBI Sequence Viewer  
  CAL18375 (Get FASTA)   NCBI Sequence Viewer  
  CAL18376 (Get FASTA)   NCBI Sequence Viewer  
  CAL18377 (Get FASTA)   NCBI Sequence Viewer  
  CAL18378 (Get FASTA)   NCBI Sequence Viewer  
  CAL18379 (Get FASTA)   NCBI Sequence Viewer  
  CAL18380 (Get FASTA)   NCBI Sequence Viewer  
  CAL18619 (Get FASTA)   NCBI Sequence Viewer  
  CAL18620 (Get FASTA)   NCBI Sequence Viewer  
  CAL18621 (Get FASTA)   NCBI Sequence Viewer  
  CAL18622 (Get FASTA)   NCBI Sequence Viewer  
  CAL18623 (Get FASTA)   NCBI Sequence Viewer  
  CAL18624 (Get FASTA)   NCBI Sequence Viewer  
  CAM91152 (Get FASTA)   NCBI Sequence Viewer  
  CAN37626 (Get FASTA)   NCBI Sequence Viewer  
  CBI12209 (Get FASTA)   NCBI Sequence Viewer  
  CBX47660 (Get FASTA)   NCBI Sequence Viewer  
  CBX54352 (Get FASTA)   NCBI Sequence Viewer  
  CCW44111 (Get FASTA)   NCBI Sequence Viewer  
  CDI30193 (Get FASTA)   NCBI Sequence Viewer  
  DAA06340 (Get FASTA)   NCBI Sequence Viewer  
  EAW92098 (Get FASTA)   NCBI Sequence Viewer  
  EAW92099 (Get FASTA)   NCBI Sequence Viewer  
  EAW92100 (Get FASTA)   NCBI Sequence Viewer  
  EAW92101 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000259523.6
  ENSP00000367207.3
  ENSP00000429441.2
  ENSP00000430235
  ENSP00000430235.2
  ENSP00000478887
  ENSP00000478887.2
  ENSP00000493139.1
  ENSP00000493145.1
  ENSP00000499105.1
  ENSP00000499182.1
  ENSP00000516742.1
  ENSP00000516743.1
  ENSP00000516744.1
  ENSP00000516745.1
GenBank Protein P01106 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_002458   ⟸   NM_002467
- Peptide Label: isoform 1
- UniProtKB: P01107 (UniProtKB/Swiss-Prot),   H0YBT0 (UniProtKB/Swiss-Prot),   A8WFE7 (UniProtKB/Swiss-Prot),   A0A087WUS5 (UniProtKB/Swiss-Prot),   A0A024R9L7 (UniProtKB/Swiss-Prot),   Q14026 (UniProtKB/Swiss-Prot),   P01106 (UniProtKB/Swiss-Prot),   B4E1N7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001341799   ⟸   NM_001354870
- Peptide Label: isoform 2
- UniProtKB: B4E1N7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000429441   ⟸   ENST00000517291
Ensembl Acc Id: ENSP00000478887   ⟸   ENST00000621592
Ensembl Acc Id: ENSP00000499182   ⟸   ENST00000651626
Ensembl Acc Id: ENSP00000259523   ⟸   ENST00000259523
Ensembl Acc Id: ENSP00000499105   ⟸   ENST00000652288
Ensembl Acc Id: ENSP00000367207   ⟸   ENST00000377970
Ensembl Acc Id: ENSP00000493145   ⟸   ENST00000641036
Ensembl Acc Id: ENSP00000493139   ⟸   ENST00000641252
Ensembl Acc Id: ENSP00000430235   ⟸   ENST00000524013
Ensembl Acc Id: ENSP00000516742   ⟸   ENST00000707113
Ensembl Acc Id: ENSP00000516745   ⟸   ENST00000707116
Ensembl Acc Id: ENSP00000516743   ⟸   ENST00000707114
Ensembl Acc Id: ENSP00000516744   ⟸   ENST00000707115
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P01106-F1-model_v2 AlphaFold P01106 1-439 view protein structure

Promoters
RGD ID:7214171
Promoter ID:EPDNEW_H12831
Type:initiation region
Name:MYC_5
Description:MYC proto-oncogene, bHLH transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12833  EPDNEW_H12832  EPDNEW_H12834  EPDNEW_H12835  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388127,735,433 - 127,735,493EPDNEW
RGD ID:7214175
Promoter ID:EPDNEW_H12832
Type:initiation region
Name:MYC_3
Description:MYC proto-oncogene, bHLH transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12831  EPDNEW_H12833  EPDNEW_H12834  EPDNEW_H12835  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388127,735,608 - 127,735,668EPDNEW
RGD ID:7214173
Promoter ID:EPDNEW_H12833
Type:multiple initiation site
Name:MYC_2
Description:MYC proto-oncogene, bHLH transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12831  EPDNEW_H12832  EPDNEW_H12834  EPDNEW_H12835  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388127,736,070 - 127,736,130EPDNEW
RGD ID:7214177
Promoter ID:EPDNEW_H12834
Type:initiation region
Name:MYC_1
Description:MYC proto-oncogene, bHLH transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12831  EPDNEW_H12833  EPDNEW_H12832  EPDNEW_H12835  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388127,736,231 - 127,736,291EPDNEW
RGD ID:7214179
Promoter ID:EPDNEW_H12835
Type:initiation region
Name:MYC_4
Description:MYC proto-oncogene, bHLH transcription factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H12831  EPDNEW_H12833  EPDNEW_H12832  EPDNEW_H12834  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh388127,736,625 - 127,736,685EPDNEW
RGD ID:6806719
Promoter ID:HG_KWN:62084
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000259523,   ENST00000391671,   NM_002467,   UC003YSH.1
Position:
Human AssemblyChrPosition (strand)Source
Build 368128,816,751 - 128,817,857 (+)MPROMDB
RGD ID:6850236
Promoter ID:EP11146
Type:single initiation site
Name:HS_MYC_1
Description:c-myc (cellular homologue of myelocytomatosis virus 29 oncogene),promoter 1.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 52; Mammalian c-myc proto-oncogene, promoter 1.
Alternative Promoters:alternative promoter #1 of 2; 5' exon 1; site 1.; see alsoEP11148  
Experiment Methods:Nuclease protection; Nuclease protection; transfected or transformed cells; Primer extension
Regulation:(induced by or strongly expressed in) mitogen; (induced by or strongly expressed in) IL (repressed by or weakly expressed in) 2
Position:
Human AssemblyChrPosition (strand)Source
Build 368128,817,498 - 128,817,558EPD
RGD ID:6850242
Promoter ID:EP11148
Type:single initiation site
Name:HS_MYC_2
Description:c-myc (cellular homologue of myelocytomatosis virus 29 oncogene),promoter 2.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 53; Mammalian c-myc proto-oncogene, promoter 2.
Alternative Promoters:alternative promoter #2 of 2; 5' exon 1; site 2; major promoter.; see alsoEP11146  
Experiment Methods:Nuclease protection; Nuclease protection; transfected or transformed cells; Length measurement of an RNA product; low-precision data
Regulation:(induced by or strongly expressed in) mitogen
Position:
Human AssemblyChrPosition (strand)Source
Build 368128,817,660 - 128,817,720EPD
RGD ID:6814821
Promoter ID:HG_XEF:8093
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001013163,   NM_001030952,   NM_001037875,   NM_001085896,   NM_001090653,   NM_001124622,   NM_001124699,   NM_001142873,   NM_001173446,   NM_023326,   NM_131412,   NM_200172,   NM_204059
Position:
Human AssemblyChrPosition (strand)Source
Build 368128,818,771 - 128,820,302 (+)MPROMDB
RGD ID:6813459
Promoter ID:HG_ACW:78838
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:MYC.HAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 368128,820,631 - 128,821,572 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:7553 AgrOrtholog
COSMIC MYC COSMIC
Ensembl Genes ENSG00000136997 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000259523.10 UniProtKB/TrEMBL
  ENST00000377970.6 UniProtKB/Swiss-Prot
  ENST00000517291.2 UniProtKB/TrEMBL
  ENST00000524013 ENTREZGENE
  ENST00000524013.2 UniProtKB/Swiss-Prot
  ENST00000621592 ENTREZGENE
  ENST00000621592.8 UniProtKB/Swiss-Prot
  ENST00000641036.1 UniProtKB/TrEMBL
  ENST00000641252.1 UniProtKB/TrEMBL
  ENST00000651626.1 UniProtKB/TrEMBL
  ENST00000652288.1 UniProtKB/Swiss-Prot
  ENST00000707113.1 UniProtKB/Swiss-Prot
  ENST00000707114.1 UniProtKB/Swiss-Prot
  ENST00000707115.1 UniProtKB/Swiss-Prot
  ENST00000707116.1 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000136997 GTEx
HGNC ID HGNC:7553 ENTREZGENE
Human Proteome Map MYC Human Proteome Map
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myc-LZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myc_transcription_factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tscrpt_reg_Myc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tscrpt_reg_Myc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:4609 UniProtKB/Swiss-Prot
NCBI Gene 4609 ENTREZGENE
OMIM 190080 OMIM
PANTHER MYC PROTO-ONCOGENE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYC PROTO-ONCOGENE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myc-LZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA31353 PharmGKB
PIRSF Myc_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS LEUZIPPRMYC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024R9L7 ENTREZGENE
  A0A087WUS5 ENTREZGENE
  A0A0B4J1R1_HUMAN UniProtKB/TrEMBL
  A0A224B085_HUMAN UniProtKB/TrEMBL
  A0A494C1T8_HUMAN UniProtKB/TrEMBL
  A0N2G3_HUMAN UniProtKB/TrEMBL
  A8WFE7 ENTREZGENE
  B0B0N9_HUMAN UniProtKB/TrEMBL
  B3CJ63_HUMAN UniProtKB/TrEMBL
  B3CJ64_HUMAN UniProtKB/TrEMBL
  B3CJ65_HUMAN UniProtKB/TrEMBL
  B3CJ66_HUMAN UniProtKB/TrEMBL
  B3CJ69_HUMAN UniProtKB/TrEMBL
  B3CJ71_HUMAN UniProtKB/TrEMBL
  B3CJ72_HUMAN UniProtKB/TrEMBL
  B3CJ73_HUMAN UniProtKB/TrEMBL
  B3CJ74_HUMAN UniProtKB/TrEMBL
  B3CJ75_HUMAN UniProtKB/TrEMBL
  B3CJ76_HUMAN UniProtKB/TrEMBL
  B3CJ77_HUMAN UniProtKB/TrEMBL
  B3CJ78_HUMAN UniProtKB/TrEMBL
  B3CJ81_HUMAN UniProtKB/TrEMBL
  B3CJ82_HUMAN UniProtKB/TrEMBL
  B3CJ86_HUMAN UniProtKB/TrEMBL
  B3CJ87_HUMAN UniProtKB/TrEMBL
  B3CJ88_HUMAN UniProtKB/TrEMBL
  B3CJ89_HUMAN UniProtKB/TrEMBL
  B3CJ90_HUMAN UniProtKB/TrEMBL
  B3CJ91_HUMAN UniProtKB/TrEMBL
  B3CJ92_HUMAN UniProtKB/TrEMBL
  B3CJ93_HUMAN UniProtKB/TrEMBL
  B3CJ94_HUMAN UniProtKB/TrEMBL
  B3CJA1_HUMAN UniProtKB/TrEMBL
  B3CJA3_HUMAN UniProtKB/TrEMBL
  B3CJA4_HUMAN UniProtKB/TrEMBL
  B3CJA7_HUMAN UniProtKB/TrEMBL
  B3CJA8_HUMAN UniProtKB/TrEMBL
  B3CJA9_HUMAN UniProtKB/TrEMBL
  B3CJB0_HUMAN UniProtKB/TrEMBL
  B3CJB1_HUMAN UniProtKB/TrEMBL
  B3CJB2_HUMAN UniProtKB/TrEMBL
  B3CJB3_HUMAN UniProtKB/TrEMBL
  B3CJB8_HUMAN UniProtKB/TrEMBL
  B3CJB9_HUMAN UniProtKB/TrEMBL
  B3CJC0_HUMAN UniProtKB/TrEMBL
  B3CJC6_HUMAN UniProtKB/TrEMBL
  B3CJC7_HUMAN UniProtKB/TrEMBL
  B3CJC8_HUMAN UniProtKB/TrEMBL
  B3CJD1_HUMAN UniProtKB/TrEMBL
  B3CJD2_HUMAN UniProtKB/TrEMBL
  B3CJD3_HUMAN UniProtKB/TrEMBL
  B3CJD5_HUMAN UniProtKB/TrEMBL
  B3CJD6_HUMAN UniProtKB/TrEMBL
  B3CJD7_HUMAN UniProtKB/TrEMBL
  B3CJD8_HUMAN UniProtKB/TrEMBL
  B3CJD9_HUMAN UniProtKB/TrEMBL
  B3CJE0_HUMAN UniProtKB/TrEMBL
  B4E1N7 ENTREZGENE, UniProtKB/TrEMBL
  H0YBG3_HUMAN UniProtKB/TrEMBL
  H0YBT0 ENTREZGENE
  MYC_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  P01107 ENTREZGENE
  Q14026 ENTREZGENE
  Q14899_HUMAN UniProtKB/TrEMBL
  Q14901_HUMAN UniProtKB/TrEMBL
  Q16591_HUMAN UniProtKB/TrEMBL
UniProt Secondary A0A024R9L7 UniProtKB/Swiss-Prot
  A0A087WUS5 UniProtKB/Swiss-Prot
  A8WFE7 UniProtKB/Swiss-Prot
  H0YBT0 UniProtKB/Swiss-Prot
  P01107 UniProtKB/Swiss-Prot
  Q14026 UniProtKB/Swiss-Prot
  Q14898 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-07 MYC  MYC proto-oncogene, bHLH transcription factor  MYC  v-myc avian myelocytomatosis viral oncogene homolog  Symbol and/or name change 5135510 APPROVED
2013-07-16 MYC  v-myc avian myelocytomatosis viral oncogene homolog  MYC  v-myc myelocytomatosis viral oncogene homolog (avian)  Symbol and/or name change 5135510 APPROVED