MIR20A (microRNA 20a) - Rat Genome Database

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Gene: MIR20A (microRNA 20a) Homo sapiens
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Symbol: MIR20A
Name: microRNA 20a
RGD ID: 1352718
HGNC Page HGNC:31577
Description: Enables mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Involved in several processes, including negative regulation of macromolecule metabolic process; negative regulation of signal transduction; and regulation of angiogenesis. Located in extracellular space and extracellular vesicle. Biomarker of several diseases, including Human papillomavirus infectious disease; IgA glomerulonephritis; gastrointestinal system cancer (multiple); lung disease (multiple); and metabolic dysfunction-associated steatotic liver disease.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: C13orf25; hsa-mir-20; hsa-mir-20a; microrna 20; miR-20; mir-20a; MIR17HG; MIR20; MIRH1; MIRHG1; MIRN20; MIRN20A; miRNA20A
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381391,351,065 - 91,351,135 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1391,351,065 - 91,351,135 (+)EnsemblGRCh38hg38GRCh38
GRCh371392,003,319 - 92,003,389 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361390,801,319 - 90,801,389 (+)NCBINCBI36Build 36hg18NCBI36
Celera1372,850,290 - 72,850,360 (+)NCBICelera
Cytogenetic Map13q31.3NCBI
HuRef1372,599,154 - 72,599,224 (+)NCBIHuRef
CHM1_11391,971,959 - 91,972,029 (+)NCBICHM1_1
T2T-CHM13v2.01390,553,641 - 90,553,711 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell apoptotic process  (ISO)
cellular response to forskolin  (ISO)
cellular response to hypoxia  (IDA)
cellular response to lipopolysaccharide  (ISS)
cellular response to oxidised low-density lipoprotein particle stimulus  (IDA)
cellular response to vascular endothelial growth factor stimulus  (IDA)
embryo implantation  (ISO)
in utero embryonic development  (ISO)
inflammatory response  (IDA)
long-term synaptic potentiation  (ISO)
lung development  (ISO)
miRNA-mediated gene silencing by inhibition of translation  (IDA,IMP)
miRNA-mediated gene silencing by mRNA destabilization  (IDA)
miRNA-mediated post-transcriptional gene silencing  (HDA,IDA,IEA,IMP)
negative regulation of amyloid precursor protein biosynthetic process  (IDA)
negative regulation of apoptotic process  (ISO)
negative regulation of BMP signaling pathway  (IGI)
negative regulation of cardiac muscle cell apoptotic process  (ISS)
negative regulation of cardioblast proliferation  (ISS)
negative regulation of cell adhesion molecule production  (IMP)
negative regulation of cell migration involved in sprouting angiogenesis  (IDA)
negative regulation of chemokine-mediated signaling pathway  (IDA)
negative regulation of cytokine-mediated signaling pathway  (IDA)
negative regulation of gene expression  (IGI,IMP)
negative regulation of inflammatory response  (IDA)
negative regulation of interleukin-17 production  (IDA)
negative regulation of p38MAPK cascade  (IDA)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IDA)
negative regulation of protein kinase activity  (IDA)
negative regulation of protein serine/threonine kinase activity  (IDA)
negative regulation of sprouting angiogenesis  (IDA)
negative regulation of stress fiber assembly  (IDA)
negative regulation of toll-like receptor 4 signaling pathway  (IDA)
negative regulation of transforming growth factor beta receptor signaling pathway  (IDA,IGI)
negative regulation of vascular endothelial growth factor production  (HMP)
ossification  (ISO)
outflow tract morphogenesis  (ISS)
positive regulation of angiogenesis  (IDA)
positive regulation of BMP signaling pathway  (IDA)
positive regulation of cardiac muscle hypertrophy in response to stress  (ISS)
positive regulation of osteoblast differentiation  (IDA)
positive regulation of phagocytosis  (ISS)
positive regulation of pulmonary blood vessel remodeling  (ISS)
positive regulation of vascular associated smooth muscle cell migration  (IDA)
positive regulation of vascular associated smooth muscle cell proliferation  (IDA)
pre-B cell differentiation  (ISO)
regulation of cardiac muscle hypertrophy  (ISS)
regulation of gene expression  (ISO)
response to bacterium  (ISO)
response to wounding  (ISO)
sensory perception of sound  (ISO)
spinal cord motor neuron differentiation  (ISO)
ventricular septum morphogenesis  (ISO)
Wnt signaling pathway  (ISO)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. miR-20a regulates expression of the iron exporter ferroportin in lung cancer. Babu KR and Muckenthaler MU, J Mol Med (Berl). 2016 Mar;94(3):347-59. doi: 10.1007/s00109-015-1362-3. Epub 2015 Nov 12.
2. Association between polymorphisms of MIR17HG and risk of colorectal cancer in the Chinese Han population. Chen P, etal., Mol Genet Genomic Med. 2019 Jun;7(6):e667. doi: 10.1002/mgg3.667. Epub 2019 Apr 3.
3. MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4. Cheng D, etal., Oncotarget. 2016 Jul 19;7(29):45199-45213. doi: 10.18632/oncotarget.9900.
4. Expression of miR-20a: A serum biomarker in the diagnostic approach for hepatocellular carcinoma. Fahim A, etal., J Pak Med Assoc. 2019 Jan;69(1):29-33.
5. HPV 16 E7 inhibits OSCC cell proliferation, invasion, and metastasis by upregulating the expression of miR-20a. Hu J, etal., Tumour Biol. 2016 Jul;37(7):9433-40. doi: 10.1007/s13277-016-4817-4. Epub 2016 Jan 19.
6. Six Serum-Based miRNAs as Potential Diagnostic Biomarkers for Gastric Cancer. Huang Z, etal., Cancer Epidemiol Biomarkers Prev. 2017 Feb;26(2):188-196. doi: 10.1158/1055-9965.EPI-16-0607. Epub 2016 Oct 18.
7. Expression profile of miR-17/92 cluster is predictive of treatment response in rectal cancer. Kral J, etal., Carcinogenesis. 2018 Dec 13;39(11):1359-1367. doi: 10.1093/carcin/bgy100.
8. MicroRNA‑20a promotes inflammation via the nuclear factor‑κB signaling pathway in pediatric pneumonia. Liu Z, etal., Mol Med Rep. 2018 Jan;17(1):612-617. doi: 10.3892/mmr.2017.7899. Epub 2017 Oct 26.
9. The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer. Ottman R, etal., Oncotarget. 2016 Nov 8;7(45):73739-73753. doi: 10.18632/oncotarget.12061.
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA in human colorectal cancer by repressing RAS p21 GTPase activating protein 1 (RASA1). Sun D, etal., J Biol Chem. 2013 Mar 29;288(13):9508-18. doi: 10.1074/jbc.M112.367763. Epub 2013 Jan 15.
12. Plasma microRNA signature of patients with IgA nephropathy. Wu J, etal., Gene. 2018 Apr 5;649:80-86. doi: 10.1016/j.gene.2018.01.050. Epub 2018 Feb 6.
13. Long Noncoding RNA MIR17HG Promotes Colorectal Cancer Progression via miR-17-5p. Xu J, etal., Cancer Res. 2019 Oct 1;79(19):4882-4895. doi: 10.1158/0008-5472.CAN-18-3880. Epub 2019 Aug 13.
14. Serum miR-20a and miR-486 are potential biomarkers for discriminating colorectal neoplasia: A pilot study. Yang Q, etal., J Cancer Res Ther. 2018;14(7):1572-1577. doi: 10.4103/jcrt.JCRT_1198_16.
15. Knockdown of lncRNA H19 alleviates ox-LDL-induced HCAECs inflammation and injury by mediating miR-20a-5p/HDAC4 axis. Yang Y, etal., Inflamm Res. 2022 Sep;71(9):1109-1121. doi: 10.1007/s00011-022-01604-z. Epub 2022 Jul 19.
16. Plasma miR-17, miR-20a, miR-20b and miR-122 as potential biomarkers for diagnosis of NAFLD in type 2 diabetes mellitus patients. Ye D, etal., Life Sci. 2018 Sep 1;208:201-207. doi: 10.1016/j.lfs.2018.07.029. Epub 2018 Jul 17.
Additional References at PubMed
PMID:11679670   PMID:12554860   PMID:14573789   PMID:15126345   PMID:15325244   PMID:15944709   PMID:15978578   PMID:16381832   PMID:17135249   PMID:17205120   PMID:17604727   PMID:17616659  
PMID:18320040   PMID:18632605   PMID:18695042   PMID:18766170   PMID:18773208   PMID:18836483   PMID:19048628   PMID:19390056   PMID:19893619   PMID:20089119   PMID:20167074   PMID:20190813  
PMID:20299512   PMID:20406904   PMID:20485376   PMID:20583868   PMID:20711463   PMID:20944140   PMID:21037258   PMID:21067317   PMID:21145484   PMID:21242194   PMID:21283765   PMID:21743293  
PMID:21816922   PMID:21982160   PMID:22186140   PMID:22381757   PMID:22438230   PMID:22449978   PMID:22450430   PMID:22648654   PMID:22682761   PMID:22696064   PMID:22751500   PMID:22785209  
PMID:22825541   PMID:22901144   PMID:23056289   PMID:23059786   PMID:23087182   PMID:23203215   PMID:23246221   PMID:23285084   PMID:23307259   PMID:23308108   PMID:23333058   PMID:23515710  
PMID:23562609   PMID:23594563   PMID:23602254   PMID:23665284   PMID:23681423   PMID:23725129   PMID:23768492   PMID:23819812   PMID:23911400   PMID:23924943   PMID:23969726   PMID:24194900  
PMID:24236097   PMID:24378993   PMID:24397367   PMID:24412053   PMID:24464651   PMID:24704830   PMID:24722426   PMID:24737193   PMID:24801835   PMID:24813230   PMID:24858712   PMID:24920276  
PMID:24972566   PMID:25019203   PMID:25115392   PMID:25210495   PMID:25336585   PMID:25447536   PMID:25760688   PMID:25803820   PMID:25884400   PMID:25914476   PMID:25960225   PMID:25991015  
PMID:26012475   PMID:26031366   PMID:26032093   PMID:26097563   PMID:26117336   PMID:26165754   PMID:26238942   PMID:26286834   PMID:26318586   PMID:26337869   PMID:26498464   PMID:26525353  
PMID:26600038   PMID:26617873   PMID:26621842   PMID:26646931   PMID:26755399   PMID:26829385   PMID:27019188   PMID:27142968   PMID:27356499   PMID:27357419   PMID:27494776   PMID:27748919  
PMID:28004114   PMID:28097093   PMID:28383557   PMID:28431233   PMID:28537677   PMID:28542387   PMID:28621051   PMID:28628113   PMID:28786072   PMID:28798470   PMID:28888922   PMID:28972028  
PMID:28987542   PMID:28987820   PMID:29040713   PMID:29079708   PMID:29266846   PMID:29327611   PMID:29450946   PMID:29556924   PMID:29617404   PMID:29625108   PMID:29653364   PMID:29685003  
PMID:29710555   PMID:29864933   PMID:29886071   PMID:29940575   PMID:30092355   PMID:30227213   PMID:30249397   PMID:30268547   PMID:30336537   PMID:30452398   PMID:30497428   PMID:30513279  
PMID:30612066   PMID:30684894   PMID:30777929   PMID:30883341   PMID:30883936   PMID:30988067   PMID:31127907   PMID:31196157   PMID:31257511   PMID:31295012   PMID:31368060   PMID:31368162  
PMID:31385464   PMID:31490024   PMID:31545439   PMID:31827150   PMID:31883454   PMID:31885737   PMID:32176569   PMID:32196605   PMID:32206115   PMID:32212290   PMID:32271413   PMID:32319789  
PMID:32406197   PMID:32410584   PMID:32608284   PMID:32661238   PMID:32720422   PMID:32868134   PMID:32949564   PMID:33032635   PMID:33125611   PMID:33129959   PMID:33169883   PMID:33275223  
PMID:33275232   PMID:33349227   PMID:33385712   PMID:33773561   PMID:33788053   PMID:33821429   PMID:34108230   PMID:34183642   PMID:34187571   PMID:34197720   PMID:34235224   PMID:34237654  
PMID:34282279   PMID:34294156   PMID:34313894   PMID:34360679   PMID:34362313   PMID:34383404   PMID:34383714   PMID:34537058   PMID:34587164   PMID:34695805   PMID:34990753   PMID:35143426  
PMID:35351042   PMID:35490164   PMID:35527493   PMID:35917232   PMID:35957556   PMID:36142220   PMID:36497115   PMID:36722424   PMID:36765482   PMID:36901753   PMID:37166421   PMID:37258792  
PMID:37279073   PMID:38063098   PMID:38129137   PMID:38158676   PMID:38561726   PMID:38937450   PMID:39010137  


Genomics

Comparative Map Data
MIR20A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381391,351,065 - 91,351,135 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1391,351,065 - 91,351,135 (+)EnsemblGRCh38hg38GRCh38
GRCh371392,003,319 - 92,003,389 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361390,801,319 - 90,801,389 (+)NCBINCBI36Build 36hg18NCBI36
Celera1372,850,290 - 72,850,360 (+)NCBICelera
Cytogenetic Map13q31.3NCBI
HuRef1372,599,154 - 72,599,224 (+)NCBIHuRef
CHM1_11391,971,959 - 91,972,029 (+)NCBICHM1_1
T2T-CHM13v2.01390,553,641 - 90,553,711 (+)NCBIT2T-CHM13v2.0
Mir20a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914115,281,589 - 115,281,695 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14115,281,589 - 115,281,695 (+)EnsemblGRCm39 Ensembl
GRCm3814115,044,157 - 115,044,263 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14115,044,157 - 115,044,263 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714115,443,379 - 115,443,485 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera14113,634,725 - 113,634,831 (+)NCBICelera
Cytogenetic Map14E4NCBI
cM Map1459.4NCBI
Mir20a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81598,588,303 - 98,588,387 (+)NCBIGRCr8
mRatBN7.21592,181,084 - 92,181,168 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1592,181,084 - 92,181,168 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1596,087,873 - 96,087,957 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01597,220,739 - 97,220,823 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01594,128,145 - 94,128,229 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015100,180,334 - 100,180,418 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15100,180,334 - 100,180,418 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015103,641,357 - 103,641,441 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1591,045,764 - 91,045,848 (+)NCBICelera
Cytogenetic Map15q23NCBI
MIR20A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12242,478,462 - 42,478,520 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2242,478,462 - 42,478,520 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2242,334,150 - 42,334,208 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02242,879,711 - 42,879,769 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2242,879,711 - 42,879,769 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12242,562,184 - 42,562,242 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02242,616,563 - 42,616,621 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02242,617,626 - 42,617,684 (+)NCBIUU_Cfam_GSD_1.0
MIR20A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1160,735,099 - 60,735,196 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11160,735,109 - 60,735,179 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21166,610,513 - 66,610,583 (+)NCBISscrofa10.2Sscrofa10.2susScr3


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh37/hg19 13q11-34(chr13:19053605-115108528)x3 copy number gain See cases [RCV001353184] Chr13:19053605..115108528 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q14.12-31.3(chr13:44967523-92738168)x1 copy number loss See cases [RCV000050891] Chr13:44967523..92738168 [GRCh38]
Chr13:45541658..93390421 [GRCh37]
Chr13:44439658..92188422 [NCBI36]
Chr13:13q14.12-31.3		 pathogenic
GRCh38/hg38 13q22.3-32.1(chr13:78349126-94701844)x1 copy number loss See cases [RCV000051379] Chr13:78349126..94701844 [GRCh38]
Chr13:78923261..95354098 [GRCh37]
Chr13:77821262..94152099 [NCBI36]
Chr13:13q22.3-32.1		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:82581008-114327173)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051380]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051380]|See cases [RCV000051380] Chr13:82581008..114327173 [GRCh38]
Chr13:83155143..115085141 [GRCh37]
Chr13:82053144..114110750 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q31.1-32.1(chr13:83947821-95128969)x1 copy number loss See cases [RCV000051414] Chr13:83947821..95128969 [GRCh38]
Chr13:84521956..95781223 [GRCh37]
Chr13:83419957..94579224 [NCBI36]
Chr13:13q31.1-32.1		 pathogenic
GRCh38/hg38 13q31.2-32.1(chr13:88260962-97285754)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051415]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051415]|See cases [RCV000051415] Chr13:88260962..97285754 [GRCh38]
Chr13:88913217..97938008 [GRCh37]
Chr13:87711218..96736009 [NCBI36]
Chr13:13q31.2-32.1		 pathogenic
GRCh38/hg38 13q31.2-32.3(chr13:88323009-98888644)x1 copy number loss See cases [RCV000051416] Chr13:88323009..98888644 [GRCh38]
Chr13:88975264..99540898 [GRCh37]
Chr13:87773265..98338899 [NCBI36]
Chr13:13q31.2-32.3		 pathogenic
GRCh38/hg38 13q31.3-32.1(chr13:89549510-96657834)x1 copy number loss See cases [RCV000051417] Chr13:89549510..96657834 [GRCh38]
Chr13:90201764..97310088 [GRCh37]
Chr13:88999765..96108089 [NCBI36]
Chr13:13q31.3-32.1		 pathogenic
GRCh38/hg38 13q31.1-33.2(chr13:82032938-106082542)x3 copy number gain See cases [RCV000051179] Chr13:82032938..106082542 [GRCh38]
Chr13:82607073..106734891 [GRCh37]
Chr13:81505074..105532892 [NCBI36]
Chr13:13q31.1-33.2		 pathogenic
GRCh38/hg38 13q31.3(chr13:90215412-91366486)x1 copy number loss See cases [RCV000051921] Chr13:90215412..91366486 [GRCh38]
Chr13:90867666..92018740 [GRCh37]
Chr13:89665667..90816741 [NCBI36]
Chr13:13q31.3		 uncertain significance
GRCh38/hg38 13q31.3(chr13:90973752-93097331)x1 copy number loss See cases [RCV000051922] Chr13:90973752..93097331 [GRCh38]
Chr13:91626006..93749584 [GRCh37]
Chr13:90424007..92547585 [NCBI36]
Chr13:13q31.3		 uncertain significance
GRCh38/hg38 13q12.11-34(chr13:18946182-114304628)x3 copy number gain See cases [RCV000053726] Chr13:18946182..114304628 [GRCh38]
Chr13:19520322..115070103 [GRCh37]
Chr13:18418322..114088205 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000053731] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18565048-114327173)x3 copy number gain See cases [RCV000053719] Chr13:18565048..114327173 [GRCh38]
Chr13:19139188..115085141 [GRCh37]
Chr13:18037188..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18850545-114327173)x3 copy number gain See cases [RCV000053723] Chr13:18850545..114327173 [GRCh38]
Chr13:19296527..115085141 [GRCh37]
Chr13:18194527..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q13.2-34(chr13:33528097-114327173)x3 copy number gain See cases [RCV000053759] Chr13:33528097..114327173 [GRCh38]
Chr13:34102234..115085141 [GRCh37]
Chr13:33000234..114110750 [NCBI36]
Chr13:13q13.2-34		 pathogenic
GRCh38/hg38 13q14.11-34(chr13:43219125-114327314)x3 copy number gain See cases [RCV000053762] Chr13:43219125..114327314 [GRCh38]
Chr13:43793261..115085141 [GRCh37]
Chr13:42691261..114110891 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q14.11-34(chr13:44164751-114327173)x3 copy number gain See cases [RCV000053764] Chr13:44164751..114327173 [GRCh38]
Chr13:44738887..115085141 [GRCh37]
Chr13:43636887..114110750 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q14.12-34(chr13:44733046-114327173)x3 copy number gain See cases [RCV000053767] Chr13:44733046..114327173 [GRCh38]
Chr13:45307182..115085141 [GRCh37]
Chr13:44205182..114110750 [NCBI36]
Chr13:13q14.12-34		 pathogenic
GRCh38/hg38 13q22.1-34(chr13:74345951-114327314)x3 copy number gain See cases [RCV000053770] Chr13:74345951..114327314 [GRCh38]
Chr13:74920088..115085141 [GRCh37]
Chr13:73818089..114110891 [NCBI36]
Chr13:13q22.1-34		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:80628584-114327173)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053772]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053772]|See cases [RCV000053772] Chr13:80628584..114327173 [GRCh38]
Chr13:81202719..115085141 [GRCh37]
Chr13:80100720..114110750 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q31.3(chr13:90644219-92557099)x1 copy number loss See cases [RCV000234861] Chr13:90644219..92557099 [GRCh37]
Chr13:13q31.3		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114298614)x3 copy number gain See cases [RCV000134104] Chr13:19833130..114298614 [GRCh38]
Chr13:20407270..115064089 [GRCh37]
Chr13:19305270..114082191 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18445862-114327173)x1 copy number loss See cases [RCV000135610] Chr13:18445862..114327173 [GRCh38]
Chr13:19020001..115085141 [GRCh37]
Chr13:10098739..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q22.3-31.3(chr13:77061780-92460406)x1 copy number loss See cases [RCV000136886] Chr13:77061780..92460406 [GRCh38]
Chr13:77635915..93112659 [GRCh37]
Chr13:76533916..91910660 [NCBI36]
Chr13:13q22.3-31.3		 pathogenic
GRCh38/hg38 13q31.2-34(chr13:88937651-114327173)x3 copy number gain See cases [RCV000137102] Chr13:88937651..114327173 [GRCh38]
Chr13:89589905..115085141 [GRCh37]
Chr13:88387906..114110750 [NCBI36]
Chr13:13q31.2-34		 pathogenic
GRCh38/hg38 13q31.1-31.3(chr13:84005264-92784013)x1 copy number loss See cases [RCV000137272] Chr13:84005264..92784013 [GRCh38]
Chr13:84579399..93436266 [GRCh37]
Chr13:83477400..92234267 [NCBI36]
Chr13:13q31.1-31.3		 likely pathogenic
GRCh38/hg38 13q14.11-34(chr13:40942298-114340331)x1 copy number loss See cases [RCV000137893] Chr13:40942298..114340331 [GRCh38]
Chr13:41516434..115085141 [GRCh37]
Chr13:40414434..114123908 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:78999318-114327106)x3 copy number gain See cases [RCV000138742] Chr13:78999318..114327106 [GRCh38]
Chr13:79573453..115085141 [GRCh37]
Chr13:78471454..114110683 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:86788927-114340331)x1 copy number loss See cases [RCV000138340] Chr13:86788927..114340331 [GRCh38]
Chr13:87441182..115085141 [GRCh37]
Chr13:86239183..114123908 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114327106)x3 copy number gain See cases [RCV000139078] Chr13:19833130..114327106 [GRCh38]
Chr13:20407270..115085141 [GRCh37]
Chr13:19305270..114110683 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q31.2-32.3(chr13:87944479-99866542)x1 copy number loss See cases [RCV000139047] Chr13:87944479..99866542 [GRCh38]
Chr13:88596734..100518796 [GRCh37]
Chr13:87394735..99316797 [NCBI36]
Chr13:13q31.2-32.3		 pathogenic
GRCh38/hg38 13q11-34(chr13:18456040-114340285)x3 copy number gain See cases [RCV000140004] Chr13:18456040..114340285 [GRCh38]
Chr13:19030180..115105760 [GRCh37]
Chr13:17928180..114123862 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:78964223-114340331)x3 copy number gain See cases [RCV000141248] Chr13:78964223..114340331 [GRCh38]
Chr13:79538358..115085141 [GRCh37]
Chr13:78436359..114123908 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q31.1-31.3(chr13:84052824-91838339)x3 copy number gain See cases [RCV000141994] Chr13:84052824..91838339 [GRCh38]
Chr13:84626959..92490593 [GRCh37]
Chr13:83524960..91288594 [NCBI36]
Chr13:13q31.1-31.3		 uncertain significance
GRCh38/hg38 13q31.1-34(chr13:83288131-114342258)x3 copy number gain See cases [RCV000141804] Chr13:83288131..114342258 [GRCh38]
Chr13:83862266..115107733 [GRCh37]
Chr13:82760267..114125835 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19671934-114340331)x3 copy number gain See cases [RCV000142924] Chr13:19671934..114340331 [GRCh38]
Chr13:20246074..115085141 [GRCh37]
Chr13:19144074..114123908 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q31.3(chr13:91283077-91394459)x1 copy number loss See cases [RCV000143094] Chr13:91283077..91394459 [GRCh38]
Chr13:91935331..92046713 [GRCh37]
Chr13:90733332..90844714 [NCBI36]
Chr13:13q31.3		 pathogenic
GRCh38/hg38 13q31.3(chr13:91282882-91394459)x1 copy number loss See cases [RCV000143162] Chr13:91282882..91394459 [GRCh38]
Chr13:91935136..92046713 [GRCh37]
Chr13:90733137..90844714 [NCBI36]
Chr13:13q31.3		 pathogenic
GRCh38/hg38 13q11-34(chr13:18862146-114342258)x3 copy number gain See cases [RCV000143462] Chr13:18862146..114342258 [GRCh38]
Chr13:19436286..115107733 [GRCh37]
Chr13:18334286..114125835 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000148126] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q31.2-34(chr13:89796110-115083342)x1 copy number loss See cases [RCV000240161] Chr13:89796110..115083342 [GRCh37]
Chr13:13q31.2-34		 pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092569)x3 copy number gain See cases [RCV000240150] Chr13:19571503..115092569 [GRCh37]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q31.3(chr13:91209639-94704856)x3 copy number gain See cases [RCV000240035] Chr13:91209639..94704856 [GRCh37]
Chr13:13q31.3		 uncertain significance
GRCh37/hg19 13q31.3(chr13:91284502-92325104)x1 copy number loss See cases [RCV002285045] Chr13:91284502..92325104 [GRCh37]
Chr13:13q31.3		 pathogenic
GRCh37/hg19 13q22.1-31.3(chr13:74459395-93481294)x1 copy number loss See cases [RCV000598789] Chr13:74459395..93481294 [GRCh37]
Chr13:13q22.1-31.3		 pathogenic
GRCh37/hg19 13q14.3-33.3(chr13:53551300-109850651)x1 copy number loss See cases [RCV000449272] Chr13:53551300..109850651 [GRCh37]
Chr13:13q14.3-33.3		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61424168-115107733)x3 copy number gain See cases [RCV000449118] Chr13:61424168..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092510) copy number gain See cases [RCV000449142] Chr13:19571503..115092510 [GRCh37]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q31.1-31.3(chr13:86963003-93390362)x3 copy number gain See cases [RCV000446248] Chr13:86963003..93390362 [GRCh37]
Chr13:13q31.1-31.3		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:82221361-115092569)x3 copy number gain See cases [RCV000447429] Chr13:82221361..115092569 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q21.1-34(chr13:56431743-115107733) copy number gain See cases [RCV000510722] Chr13:56431743..115107733 [GRCh37]
Chr13:13q21.1-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain See cases [RCV000445886] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q31.1-33.1(chr13:81851091-102864674)x1 copy number loss See cases [RCV000448988] Chr13:81851091..102864674 [GRCh37]
Chr13:13q31.1-33.1		 pathogenic
GRCh37/hg19 13q31.2-34(chr13:88073140-115107733)x1 copy number loss See cases [RCV000448405] Chr13:88073140..115107733 [GRCh37]
Chr13:13q31.2-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733) copy number gain See cases [RCV000510405] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.33-34(chr13:71871468-115107733)x4 copy number gain See cases [RCV000510281] Chr13:71871468..115107733 [GRCh37]
Chr13:13q21.33-34		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:80058840-115107733)x3 copy number gain See cases [RCV000510566] Chr13:80058840..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733)x3 copy number gain See cases [RCV000511880] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q31.1-33.3(chr13:80572498-108719528)x1 copy number loss See cases [RCV000510890] Chr13:80572498..108719528 [GRCh37]
Chr13:13q31.1-33.3		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:83435292-115107733)x3 copy number gain See cases [RCV000512605] Chr13:83435292..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q14.3-32.1(chr13:53932358-96586363)x3 copy number gain See cases [RCV000512571] Chr13:53932358..96586363 [GRCh37]
Chr13:13q14.3-32.1		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:85176519-115107733)x3 copy number gain See cases [RCV000512242] Chr13:85176519..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
Single allele duplication not provided [RCV000678035] Chr13:91209639..94704856 [GRCh37]
Chr13:13q31.3		 likely pathogenic
GRCh37/hg19 13q22.3-34(chr13:78590089-115107733)x3 copy number gain not provided [RCV000683571] Chr13:78590089..115107733 [GRCh37]
Chr13:13q22.3-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19058717-115103529)x3 copy number gain not provided [RCV000738115] Chr13:19058717..115103529 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q31.1-31.3(chr13:85005334-92461147)x1 copy number loss not provided [RCV000738268] Chr13:85005334..92461147 [GRCh37]
Chr13:13q31.1-31.3		 pathogenic
GRCh37/hg19 13q11-34(chr13:19031237-115107157)x3 copy number gain not provided [RCV000750643] Chr13:19031237..115107157 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.1-31.3(chr13:57058434-94684615)x1 copy number loss not provided [RCV000750731] Chr13:57058434..94684615 [GRCh37]
Chr13:13q21.1-31.3		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61775567-115107733)x3 copy number gain not provided [RCV000848025] Chr13:61775567..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV000849129] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q31.3(chr13:91460305-92069153)x3 copy number gain not provided [RCV001006582] Chr13:91460305..92069153 [GRCh37]
Chr13:13q31.3		 likely pathogenic
GRCh37/hg19 13q14.3-34(chr13:53262013-115107733)x1 copy number loss not provided [RCV001006567] Chr13:53262013..115107733 [GRCh37]
Chr13:13q14.3-34		 pathogenic
NC_000013.10:g.(?_92002837)_(103343314_?)del deletion Holoprosencephaly 5 [RCV001388033] Chr13:92002837..103343314 [GRCh37]
Chr13:13q31.3-33.1		 pathogenic
GRCh37/hg19 13p13-q34(chr13:1-115169878)x3 copy number gain See cases [RCV001780076] Chr13:1..115169878 [GRCh37]
Chr13:13p13-q34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733) copy number gain not specified [RCV002053036] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q14.11-33.3(chr13:42504540-108206269)x3 copy number gain not provided [RCV001829235] Chr13:42504540..108206269 [GRCh37]
Chr13:13q14.11-33.3		 pathogenic
GRCh37/hg19 13q22.3-34(chr13:78514567-115107733) copy number gain not specified [RCV002053071] Chr13:78514567..115107733 [GRCh37]
Chr13:13q22.3-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV001834436] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-114981726) copy number gain not specified [RCV002053035] Chr13:19436286..114981726 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:79370012-115107733) copy number loss not specified [RCV002053072] Chr13:79370012..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61424168-115107733) copy number gain not specified [RCV002053063] Chr13:61424168..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:85037147-115107733) copy number gain not specified [RCV002053073] Chr13:85037147..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q31.2-34(chr13:88073140-115107733) copy number loss not specified [RCV002053074] Chr13:88073140..115107733 [GRCh37]
Chr13:13q31.2-34		 pathogenic
GRCh37/hg19 13q31.2-34(chr13:89490345-115062235)x3 copy number gain See cases [RCV002286354] Chr13:89490345..115062235 [GRCh37]
Chr13:13q31.2-34		 pathogenic
GRCh37/hg19 13p13-q34(chr13:1-115169878) copy number gain Complete trisomy 13 syndrome [RCV002280659] Chr13:1..115169878 [GRCh37]
Chr13:13p13-q34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19253848-115108937)x3 copy number gain not provided [RCV002291540] Chr13:19253848..115108937 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q22.1-34(chr13:75268539-115107733)x3 copy number gain not provided [RCV002472537] Chr13:75268539..115107733 [GRCh37]
Chr13:13q22.1-34		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:82131211-115107733)x1 copy number loss not provided [RCV003483192] Chr13:82131211..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61534068-115107733)x3 copy number gain not provided [RCV003484899] Chr13:61534068..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
GRCh37/hg19 13q21.33-33.1(chr13:73132193-104595598)x1 copy number loss not provided [RCV003483190] Chr13:73132193..104595598 [GRCh37]
Chr13:13q21.33-33.1		 pathogenic
GRCh37/hg19 13q22.1-34(chr13:73488238-115107733)x3 copy number gain not provided [RCV003484901] Chr13:73488238..115107733 [GRCh37]
Chr13:13q22.1-34		 pathogenic
GRCh37/hg19 13q31.2-33.2(chr13:89012420-106371634)x1 copy number loss not provided [RCV003483195] Chr13:89012420..106371634 [GRCh37]
Chr13:13q31.2-33.2		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:84669397-115107733)x1 copy number loss not specified [RCV003987038] Chr13:84669397..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q14.2-32.2(chr13:49547974-98214905)x1 copy number loss not specified [RCV003987008] Chr13:49547974..98214905 [GRCh37]
Chr13:13q14.2-32.2		 pathogenic
GRCh37/hg19 13q21.1-31.3(chr13:56450978-93582180)x1 copy number loss not specified [RCV003987013] Chr13:56450978..93582180 [GRCh37]
Chr13:13q21.1-31.3		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:82876219-115107733)x3 copy number gain not specified [RCV003987023] Chr13:82876219..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q21.31-33.1(chr13:64825656-103641349)x1 copy number loss not specified [RCV003987009] Chr13:64825656..103641349 [GRCh37]
Chr13:13q21.31-33.1		 pathogenic
miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
HIF1Ahsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blot//Northern Functional MTI18632605
CCND1hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI18695042
CCND1hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21283765
E2F1hsa-miR-20a-5pMirtarbaseexternal_infoWestern blotFunctional MTI19110058
E2F1hsa-miR-20a-5pMirtarbaseexternal_infoWestern blotFunctional MTI18025036
E2F1hsa-miR-20a-5pMirtarbaseexternal_infoWestern blotFunctional MTI18836483
E2F1hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//Northern blot//Western Functional MTI15944709
BMPR2hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19390056
CDKN1Ahsa-miR-20a-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI20190813
CDKN1Ahsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR;OtherFunctional MTI18941111
EGLN3hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI22182733
TGFBR2hsa-miR-20a-5pMirtarbaseexternal_infoImmunoblot//Luciferase reporter assay//Microarray/Functional MTI20940405
TGFBR2hsa-miR-20a-5pMirtarbaseexternal_infoMicroarray//qRT-PCRFunctional MTI (Weak)19435428
TGFBR2hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//Microarray//Reporter asFunctional MTI16461460
MAP3K12hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19666108
PTENhsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotNon-Functional MTI20008935
APPhsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19110058
APPhsa-miR-20a-5pMirtarbaseexternal_infoGFP reporter assay//qRT-PCR//Western blotFunctional MTI20458444
RUNX1hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI17589498
NRAShsa-miR-20a-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI19110058
VEGFAhsa-miR-20a-5pMirtarbaseexternal_infoELISA//Luciferase reporter assayFunctional MTI18320040
MUC17hsa-miR-20a-5pMirtarbaseexternal_infoImmunohistochemistry//Microarray//qRT-PCRFunctional MTI (Weak)20926598
MYChsa-miR-20a-5pMirtarbaseexternal_infoWestern blotFunctional MTI18695042
BNIP2hsa-miR-20a-5pMirtarbaseexternal_infoqRT-PCR//Western blotFunctional MTI21242194
BNIP2hsa-miR-20a-5pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248
THBS1hsa-miR-20a-5pMirtarbaseexternal_infoMicroarray//qRT-PCRNon-Functional MTI (Weak)20940405
SMAD4hsa-miR-20a-5pMirtarbaseexternal_infoMicroarrayNon-Functional MTI (Weak)20940405
E2F3hsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assayNon-Functional MTI21283765
PURAhsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI22835829
ARHGAP12hsa-miR-20a-5pMirtarbaseexternal_infoReporter assayFunctional MTI21751348
SIRPAhsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23562609
E2F1hsa-miR-20a-5pTarbaseexternal_infoReporter GenePOSITIVE
CDKN1Ahsa-miR-20a-5pTarbaseexternal_infoqPCRPOSITIVE
CDKN1Ahsa-miR-20a-5pOncomiRDBexternal_infoNANA23333058
CDKN1Ahsa-miR-20a-5pOncomiRDBexternal_infoNANA23059786
GJA1hsa-miR-20a-5pOncomiRDBexternal_infoNANA22785209
TNKS2hsa-miR-20a-5pOncomiRDBexternal_infoNANA22449978
FAShsa-miR-20a-5pOncomiRDBexternal_infoNANA22186140
ZBTB4hsa-miR-20a-5pOncomiRDBexternal_infoNANA21765466
BNIP2hsa-miR-20a-5pOncomiRDBexternal_infoNANA21242194
CDKN1Ahsa-miR-20a-5pOncomiRDBexternal_infoNANA20851997
STAT3hsa-miR-20a-5pOncomiRDBexternal_infoNANA20583868
APPhsa-miR-20a-5pOncomiRDBexternal_infoNANA20458444
CXCL8hsa-miR-20a-5pOncomiRDBexternal_infoNANA20406904
CCND1hsa-miR-20a-5pOncomiRDBexternal_infoNANA18695042
E2F2hsa-miR-20a-5pOncomiRDBexternal_infoNANA17135249
YTHDC1hsa-miR-20a-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248
E2F1hsa-miR-20a-3pMirecordsexternal_infoNANA15944709
RUNX1hsa-miR-20a-3pMirecordsexternal_info{unchanged}{unchanged}NA17589498
CCND1hsa-miR-20a-3pMirecordsexternal_info{unchanged}NA18695042
JAK1hsa-miR-20a-3pMirecordsexternal_info{changed}NA20299512
BCL2hsa-miR-20a-3pMirecordsexternal_info{changed}NA19666108
CCND1hsa-miR-20a-3pMirecordsexternal_info{unchanged}NA19823025
BMPR2hsa-miR-20a-3pMirecordsexternal_info{changed}NA19390056

Predicted Targets
Summary Value
Count of predictions:40722
Count of gene targets:12918
Count of transcripts:26192
Interacting mature miRNAs:hsa-miR-20a-3p, hsa-miR-20a-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289426BW213_HBody weight QTL 213 (human)2.780.0002Body weightBMI1384267977110267977Human
2289433BW340_HBody weight QTL 340 (human)3.11Body morphometrywaist circumference1384267977110267977Human


Sequence


Ensembl Acc Id: ENST00000362279
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1391,351,065 - 91,351,135 (+)Ensembl
RefSeq Acc Id: NR_029492
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381391,351,065 - 91,351,135 (+)NCBI
GRCh371392,003,319 - 92,003,389 (+)ENTREZGENE
HuRef1372,599,154 - 72,599,224 (+)ENTREZGENE
CHM1_11391,971,959 - 91,972,029 (+)NCBI
T2T-CHM13v2.01390,553,641 - 90,553,711 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31577 AgrOrtholog
COSMIC MIR20A COSMIC
Ensembl Genes ENSG00000283762 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000362279 ENTREZGENE
GTEx ENSG00000283762 GTEx
HGNC ID HGNC:31577 ENTREZGENE
Human Proteome Map MIR20A Human Proteome Map
miRBase MI0000076 ENTREZGENE
NCBI Gene 406982 ENTREZGENE
OMIM 609420 OMIM
PharmGKB PA164722588 PharmGKB
RNAcentral URS0000042E1F RNACentral
  URS0000507C9B RNACentral
  URS0000574A2C RNACentral