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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731438
Species: Homo sapiens
RGD Object: Gene
Symbol: MYC
Name: MYC proto-oncogene, bHLH transcription factor
Acc ID: CHEBI:88542
Term: Butylparaben
Definition: null
Chemical ID: MESH:C038091
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MYCincreases expressionEXP 6480464CTDbutylparaben results in increased expression of MYC mRNAPMID:26502914
MYCmultiple interactionsEXP 6480464CTD[butylparaben co-treated with NRG1 protein] promotes the reaction [ESR1 protein binds to MYC enhancer]; [NRG1 protein co-treated with butylparaben] results in increased expression of MYC protein; butylparaben promotes the reaction [NRG1 protein results in increased expression of MYC mRNA]; NRG1 protein promotes the reaction [butylparaben results in increased expression of MYC mRNA]PMID:26502914
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