Symbol:
MIR378A
Name:
microRNA 378a
RGD ID:
1345940
HGNC Page
HGNC:31871
Description:
Enables mRNA base-pairing translational repressor activity. Involved in negative regulation of gene expression and negative regulation of monooxygenase activity. Located in extracellular space.
Type:
ncrna (Ensembl: miRNA)
RefSeq Status:
PROVISIONAL
Previously known as:
hsa-mir-378; hsa-mir-378a; MIR378; MIRN378; miRNA378
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 5 149,732,825 - 149,732,890 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 5 149,732,825 - 149,732,890 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 5 149,112,388 - 149,112,453 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 5 149,092,580 - 149,092,645 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 5 145,193,831 - 145,193,896 (+) NCBI Celera Cytogenetic Map 5 q32 NCBI HuRef 5 144,259,553 - 144,259,618 (+) NCBI HuRef CHM1_1 5 148,544,808 - 148,544,873 (+) NCBI CHM1_1 T2T-CHM13v2.0 5 150,269,381 - 150,269,446 (+) NCBI T2T-CHM13v2.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
MIR378A Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 5 149,732,825 - 149,732,890 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 5 149,732,825 - 149,732,890 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 5 149,112,388 - 149,112,453 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 5 149,092,580 - 149,092,645 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 5 145,193,831 - 145,193,896 (+) NCBI Celera Cytogenetic Map 5 q32 NCBI HuRef 5 144,259,553 - 144,259,618 (+) NCBI HuRef CHM1_1 5 148,544,808 - 148,544,873 (+) NCBI CHM1_1 T2T-CHM13v2.0 5 150,269,381 - 150,269,446 (+) NCBI T2T-CHM13v2.0
Mir378a Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 18 61,530,906 - 61,530,971 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 18 61,530,906 - 61,530,971 (-) Ensembl GRCm39 Ensembl GRCm38 18 61,397,835 - 61,397,900 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 18 61,397,835 - 61,397,900 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 18 61,557,489 - 61,557,554 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 Celera 18 62,681,400 - 62,681,465 (-) NCBI Celera Cytogenetic Map 18 E1 NCBI cM Map 18 34.62 NCBI
MIR378 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 4 59,276,347 - 59,276,406 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 4 59,276,336 - 59,276,417 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 4 59,042,100 - 59,042,159 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 4 59,758,554 - 59,758,613 (-) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 4 59,545,644 - 59,545,703 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 4 59,660,139 - 59,660,198 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 4 60,191,371 - 60,191,430 (-) NCBI UU_Cfam_GSD_1.0
MIR378-1 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 2 150,825,865 - 150,825,944 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 2 150,825,865 - 150,825,944 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 2 157,640,353 - 157,640,432 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
.
Confirmed Targets
SUFU hsa-miR-378a-5p Mirtarbase external_info Luciferase reporter assay//Western blot//qRT-PCR Functional MTI 18077375 PPARGC1A hsa-miR-378a-5p Mirtarbase external_info CLASH Functional MTI (Weak) 23622248 SUFU hsa-miR-378a-3p Mirtarbase external_info Reporter assay Functional MTI 18077375 VEGFA hsa-miR-378a-3p Mirtarbase external_info ELISA//Luciferase reporter assay Non-Functional MTI 18320040 NPNT hsa-miR-378a-3p Mirtarbase external_info GFP reporter assay//Luciferase reporter assay//Wes Functional MTI 19844573 MYC hsa-miR-378a-3p Mirtarbase external_info Immunoblot//Luciferase reporter assay//qRT-PCR Functional MTI 21242960 MSC hsa-miR-378a-3p Mirtarbase external_info Luciferase reporter assay Functional MTI 21471220 GRB2 hsa-miR-378a-3p Mirtarbase external_info Luciferase reporter assay Functional MTI 23447532 VPS37B hsa-miR-378a-3p Mirtarbase external_info Sequencing Functional MTI (Weak) 20371350 LAMP1 hsa-miR-378a-3p Mirtarbase external_info CLASH Functional MTI (Weak) 23622248 SUFU hsa-miR-378a-3p Tarbase external_info Reporter Gene POSITIVE DDX39A hsa-miR-378a-3p Tarbase external_info Sequencing POSITIVE
Predicted Targets
Count of predictions: 30498 Count of gene targets: 11828 Count of transcripts: 23105 Interacting mature miRNAs: hsa-miR-378a-3p, hsa-miR-378a-5p Prediction methods: Microtar, Miranda, Pita, Rnahybrid, Targetscan Result types: miRGate_prediction
1357314 AASTH54_H Allergic/atopic asthma related QTL 54 (human) 3.56 0.0003 Reversible airflow obstruction total serum IgE 5 135892246 150155845 Human
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
entire extraembryonic component
8
167
42
59
196
144
328
3
121
387
123
140
856
495
42
77
182
193
191
5
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENST00000362177
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 5 149,732,825 - 149,732,890 (+) Ensembl
RefSeq Acc Id:
NR_029870
RefSeq Status:
PROVISIONAL
Type:
NON-CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38 5 149,732,825 - 149,732,890 (+) NCBI GRCh37 5 149,112,388 - 149,112,453 (+) RGD Celera 5 145,193,831 - 145,193,896 (+) RGD HuRef 5 144,259,553 - 144,259,618 (+) ENTREZGENE CHM1_1 5 148,544,808 - 148,544,873 (+) NCBI T2T-CHM13v2.0 5 150,269,381 - 150,269,446 (+) NCBI
Sequence:
AGGGCTCCTGACTCCAGGTCCTGTGTGTTACCTAGAAATAGCACTGGACTTGGAGTCAGAAGGCCT
hide sequence
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2011-11-22
MIR378A
microRNA 378a
MIR378
microRNA 378
Symbol and/or name change
5135510 APPROVED
