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Gene: LAMP1 (lysosomal associated membrane protein 1) Homo sapiens
Symbol: LAMP1
Name: lysosomal associated membrane protein 1
Description: Exhibits enzyme binding activity. Involved in several processes, including Golgi to lysosome transport; granzyme-mediated apoptotic signaling pathway; and positive regulation of natural killer cell degranulation. Localizes to several cellular components, including late endosome; lysosome; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD107 antigen-like family member A; CD107a; LAMP-1; LAMPA; LGP120; lysosomal membrane glycoprotein 1; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; lysosome-associated membrane protein 1
Mus musculus (house mouse) : Lamp1 (lysosomal-associated membrane protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lamp1 (lysosomal-associated membrane protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lamp1 (lysosomal associated membrane protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LAMP1 (lysosomal associated membrane protein 1)
Canis lupus familiaris (dog) : LAMP1 (lysosomal associated membrane protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lamp1 (lysosomal associated membrane protein 1)
Sus scrofa (pig) : LAMP1 (lysosomal associated membrane protein 1)
Chlorocebus sabaeus (African green monkey) : LAMP1 (lysosomal associated membrane protein 1)
Heterocephalus glaber (naked mole-rat) : Lamp1 (lysosomal associated membrane protein 1)
more info ...
Related Pseudogenes: AC090415.1   AL050305.1   LAMP1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl13113,297,239 - 113,323,672 (+)EnsemblGRCh38hg38GRCh38
GRCh3813113,297,239 - 113,323,672 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3713113,951,436 - 113,977,746 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613112,999,470 - 113,025,742 (+)NCBINCBI36hg18NCBI36
Build 3413112,999,602 - 113,025,741NCBI
Celera1394,778,100 - 94,804,252 (+)NCBI
Cytogenetic Map13q34NCBI
HuRef1394,390,382 - 94,416,378 (+)NCBIHuRef
CHM1_113113,920,516 - 113,946,732 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LAMP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737544
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.