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Gene: VPS37B (VPS37B subunit of ESCRT-I) Homo sapiens
Symbol: VPS37B
Name: VPS37B subunit of ESCRT-I
Description: Exhibits calcium-dependent protein binding activity. Involved in positive regulation of viral budding via host ESCRT complex and positive regulation of viral release from host cell. Localizes to ESCRT I complex; midbody; and plasma membrane; PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2-methylcholine; aflatoxin B1; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ESCRT-I complex subunit VPS37B; FLJ12750; hVps37B; vacuolar protein sorting 37 homolog B; vacuolar protein sorting 37B; vacuolar protein sorting-associated protein 37B; VPS37B, ESCRT-I subunit
Mus musculus (house mouse) : Vps37b (vacuolar protein sorting 37B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Vps37b (VPS37B subunit of ESCRT-I)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vps37b (VPS37B subunit of ESCRT-I)
Pan paniscus (bonobo/pygmy chimpanzee) : VPS37B (VPS37B subunit of ESCRT-I)
Canis lupus familiaris (dog) : VPS37B (VPS37B subunit of ESCRT-I)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vps37b (VPS37B subunit of ESCRT-I)
Sus scrofa (pig) : VPS37B (VPS37B subunit of ESCRT-I)
Chlorocebus sabaeus (African green monkey) : VPS37B (VPS37B subunit of ESCRT-I)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl12122,865,330 - 122,896,127 (-)EnsemblGRCh38hg38GRCh38
GRCh3812122,865,330 - 122,896,143 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712123,349,875 - 123,380,712 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612121,915,835 - 121,946,665 (-)NCBINCBI36hg18NCBI36
Celera12122,941,170 - 122,971,994 (-)NCBI
Cytogenetic Map12q24.31NCBI
HuRef12120,309,887 - 120,340,737 (-)NCBIHuRef
CHM1_112123,318,165 - 123,349,007 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on VPS37B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605953
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.